Paper: epigenetic landscape during mushroom development

Posted on: April 16, 2021

Peter Jan Vonk published a new paper about the epigenetic landscape during mushroom development. He performed ChIP-Seq on lysine 4 dimethylated histone H3, which is a marker for transcriptionally active DNA. Overall, the epigenetic landscape is similar between monokaryons (a lifestage that does not form mushrooms) and primordia (early mushroom development). However, clear differences were also seen. For example in the case of two transcription factors. Indeed, when these TFs were deleted, mushroom development was stalled.

Associated with this News:

• Mushroom development (Project)
• Robin Ohm (Lab member)
• Peter Jan Vonk (Lab member)
• H3K4me2 ChIP-Seq reveals the epigenetic landscape during mushroom formation and novel developmental regulators of Schizophyllum commune.
  Vonk PJ, Ohm RA
  Sci Rep. 2021 Apr; 11(1): 8178. doi: 10.1038/s41598-021-87635-8
  

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