Fungal Genomics

at Utrecht University

Lignocellulose degradation by mushrooms

Project description

Mushroom-forming fungi are among the most potent wood-degraders. In contrast to ascomycete fungi, many of these basidiomycete mushroom-forming fungi can degrade all the components of wood (including cellulose, lignin, hemicellulose and pectin). Many enzymes have been identified that can degrade the various components of wood, but little is known about the regulation of this process.

The aim of this project is to identify the genes involved in this process, especially regarding their regulation.


Figure. The mushroom-forming fungus Schizophyllum commune growing on wood.

Lab members currently working on this project

Genome portals


The Transcription Factor Roc1 Is a Key Regulator of Cellulose Degradation in the Wood-Decaying Mushroom Schizophyllum commune.
Marian IM, Vonk PJ, Valdes ID, Barry K, Bostock B, Carver A, Daum C, Lerner H, Lipzen A, Park H, Schuller MBP, Tegelaar M, Tritt A, Schmutz J, Grimwood J, Lugones LG, Choi IG, Wosten HAB, Grigoriev IV, Ohm RA
mBio. 2022 Jun; 13(3): e0062822. doi: 10.1128/mbio.00628-22

Cycling in degradation of organic polymers and uptake of nutrients by a litter-degrading fungus.
Vos AM, Bleichrodt RJ, Herman KC, Ohm RA, Scholtmeijer K, Schmitt H, Lugones LG, Wosten HAB
Environ Microbiol. 2021 Jan; 23(1): 224-238. doi: 10.1111/1462-2920.15297

Degradative Capacity of Two Strains of Rhodonia placenta: From Phenotype to Genotype.
Kolle M, Horta MAC, Nowrousian M, Ohm RA, Benz JP, Pilgard A
Front Microbiol. 2020 Jul; 11: 1338. doi: 10.3389/fmicb.2020.01338

© 2023 - Robin Ohm - Utrecht University - The Netherlands

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