© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Pro_DTO377G3_2|g9087.t1 |
| Gene name | |
| Location | scaffold_41:90891..94853 |
| Strand | - |
| Gene length (bp) | 3962 |
| Transcript length (bp) | 3828 |
| Coding sequence length (bp) | 3828 |
| Protein length (aa) | 1276 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF16414 | NPC1_N | Niemann-Pick C1 N terminus | 7.1E-86 | 32 | 268 |
| PF02460 | Patched | Patched family | 6.1E-50 | 511 | 880 |
| PF02460 | Patched | Patched family | 6.3E-26 | 986 | 1238 |
| PF12349 | Sterol-sensing | Sterol-sensing domain of SREBP cleavage-activation | 9.9E-52 | 635 | 788 |
| PF03176 | MMPL | MMPL family | 5.7E-05 | 562 | 775 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0016021 | integral component of membrane | Yes |
| GO:0016020 | membrane | Yes |
| GO:0110165 | cellular anatomical entity | No |
| GO:0005575 | cellular_component | No |
| GO:0031224 | intrinsic component of membrane | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| Yes | 1 - 24 | 0.45 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 269 | 291 | 22 |
| 2 | 601 | 623 | 22 |
| 3 | 638 | 660 | 22 |
| 4 | 667 | 689 | 22 |
| 5 | 717 | 739 | 22 |
| 6 | 746 | 768 | 22 |
| 7 | 832 | 854 | 22 |
| 8 | 1070 | 1092 | 22 |
| 9 | 1102 | 1124 | 22 |
| 10 | 1131 | 1153 | 22 |
| 11 | 1181 | 1203 | 22 |
| 12 | 1216 | 1238 | 22 |
Expression values
| Label | Description | Expression (RPKM) | Confidence interval (low) | Confidence interval (high) |
|---|---|---|---|---|
| 3d_25C | Three days - 25 degrees Celsius | 50.56 | 30.90 | 70.22 |
| 5d_25C | Five days - 25 degrees Celsius | 58.80 | 35.66 | 81.93 |
| 7d_25C | Seven days - 25 degrees Celsius | 59.73 | 36.05 | 83.41 |
| 10d_25C | Ten days - 25 degrees Celsius | 75.27 | 44.76 | 105.79 |
| 7d_15C | Seven days - 15 degrees Celsius | 72.10 | 42.78 | 101.42 |
| 7d_30C | Seven days - 30 degrees Celsius | 56.99 | 34.69 | 79.30 |
Differential expression
| Label1 | Label2 | Q-value | Significant difference |
|---|---|---|---|
| 3d_25C | 5d_25C | 0.564424 | no |
| 3d_25C | 7d_25C | 0.525663 | no |
| 3d_25C | 7d_15C | 0.103838 | no |
| 3d_25C | 7d_30C | 0.666419 | no |
| 3d_25C | 10d_25C | 0.065810 | no |
| 5d_25C | 7d_25C | 0.965608 | no |
| 5d_25C | 7d_15C | 0.413772 | no |
| 5d_25C | 7d_30C | 0.927469 | no |
| 5d_25C | 10d_25C | 0.298911 | no |
| 7d_25C | 7d_15C | 0.471009 | no |
| 7d_25C | 7d_30C | 0.887876 | no |
| 7d_25C | 10d_25C | 0.351618 | no |
| 7d_15C | 7d_30C | 0.325823 | no |
| 7d_15C | 10d_25C | 0.899576 | no |
| 7d_30C | 10d_25C | 0.230447 | no |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Pro_DTO377G3_2|g9087.t1 MRLPRALALIVGLGSFAPTLVGAQGETKIHEKGRCAIRGHCGKQSIFGGELPCPDNDLAQQPEDAVRQKLVNLCG SKWSEGPVCCRDEQIDALSSNLKLAEGIIASCPACRDNFFNIFCTFTCSPDQSLFINVTKTEENRSGKRLVTELD NIWSEEYQNGFYDSCKNVKNGASGGKAIDFIGGGAKDAPHFMKFLGDKKFLGSPFQINYHTEPTGPDPQGMKALS IKPKACNDEDKSFRCSCVDCPEVCPELPAISPHKICHVGLLPCLSFAVILVYSVFLLFVIALASYVTYKERRFRK PERVRLLQDPTPSDDEDEGEVMHRGGYMERSHGVYKLNSVLSAMFYRIGGACARFPAITIFSSVTGVVLLSLGWL NFTVETDPVQLWVSPSSAAAQEKDFFDQSFGPFFRAEQAFLVNNRPDNDSRPLLDYETLTWWFDVESRVRRVISL DQALNFDDVCFKPTGEACVVQSFTGYFGGSVSNLDPDTWKDRLSHCTKSPGDPSCLPDFSQPLKPEMILGGYEDT GNVLDAQALIVTWVVNNYDQGTEEEAKAIDWENTFQAVLGVVQEEAAERGLRVSFNSEVSLEQELNKSTNTDAKI VVISYLIMFFYVSMALGSVTVTWRSLLTNPSNALVQSKFTLGIVGIIIVLMSVSASVGLFSAAGVKVTLIIAEVI PFLVLAVGVDNIFLIVHEFERVNISHPDEEIDERVARAVGRIGPSIFLSALTETVAFALGIFVGMPAVKNFAAYA AGAVFINAILQITMFISVLALNQRRVQSLRADCIPCLTVRKANSFGFPGENYDGQEAESTLQVFIRRVYAPFLLD RRVKVGVVIFFLGLLTAGLAFIPEVPLGLDQRIALPSDSYLISYFNDLDSYFDTGPPVYFVTRNVNVTERSHQQQ LCGRFTTCEEYSLPFILEQESKRPNVSYLAGSAASWIDDFFYWLNPQQDCCKENGKLCFEDRVPAWNISLSGMPE GSEFVHYAQKWIDAPTDASCPLGGKAPYSNALVIDDKYKTINASHFRTSHTPLRSQNEFIEAYIAARRIADDISR EHDIDVFPYSKFYIFFDQYVSIVRLTGTLLGSAVAIIFVLTSVILGSIATGAVITTTVVMIVVDIIGTMAIAGVS LNAVSLVNLVICVGIGVEFCAHIARAFMFPARPIMDKVPAEFRGKDARAWAALVNVGGTVFSGITVTKLLGVCVL AFTRSKIFEIYYFRVWLALVIFAATHALIFLPVALSYFGGGGYFDPASEGGLEANLASRGYRSSLLHDEYESDEY * |
| Coding | >Pro_DTO377G3_2|g9087.t1 ATGCGGTTGCCTAGGGCTCTCGCCCTGATCGTTGGGCTGGGCTCTTTTGCACCTACCCTTGTCGGTGCACAGGGC GAAACTAAAATCCACGAAAAGGGCCGTTGTGCTATTCGAGGTCATTGTGGAAAGCAATCCATTTTTGGAGGTGAA CTACCCTGTCCAGATAATGACCTGGCGCAACAACCAGAAGACGCAGTACGCCAAAAGTTGGTAAATCTGTGTGGC AGCAAATGGAGCGAAGGGCCGGTCTGTTGTCGAGATGAACAGATCGATGCGCTTTCCAGTAACCTCAAACTAGCA GAGGGAATTATCGCGTCCTGCCCTGCCTGCCGAGACAACTTCTTCAACATATTCTGTACCTTTACATGCTCCCCC GATCAATCTCTTTTCATCAATGTCACCAAAACAGAAGAAAACAGATCTGGTAAAAGACTTGTGACCGAGTTGGAC AATATTTGGTCCGAGGAGTACCAGAACGGCTTCTACGATAGCTGCAAGAACGTAAAGAACGGTGCCTCGGGCGGG AAAGCCATTGACTTCATCGGCGGTGGTGCGAAAGACGCTCCCCATTTCATGAAGTTTTTAGGTGATAAGAAGTTT CTCGGGAGCCCGTTCCAGATTAACTATCACACAGAGCCCACTGGGCCTGACCCGCAAGGAATGAAGGCTTTGTCA ATAAAGCCGAAAGCCTGCAATGACGAGGACAAATCATTCCGATGTTCTTGTGTCGACTGCCCGGAAGTGTGTCCG GAGTTGCCTGCCATCTCCCCCCACAAGATATGTCATGTAGGACTTCTACCATGTCTATCGTTTGCCGTCATTCTC GTTTATTCCGTCTTTCTATTATTTGTCATTGCTCTCGCGAGCTATGTCACATACAAGGAACGCCGTTTCCGCAAA CCAGAGCGGGTGCGGTTGCTACAAGATCCCACGCCCAGCGATGACGAAGATGAAGGGGAAGTCATGCACCGTGGA GGATATATGGAAAGATCACATGGAGTATACAAGCTCAACTCTGTGTTGTCAGCTATGTTCTATCGAATCGGTGGT GCTTGTGCGCGGTTCCCAGCAATAACAATATTCTCCAGCGTCACCGGAGTGGTGCTGCTGAGCCTAGGGTGGCTA AATTTCACCGTTGAAACGGATCCGGTGCAACTCTGGGTGAGTCCGTCATCTGCGGCCGCCCAGGAGAAGGATTTC TTCGATCAGAGCTTTGGTCCATTCTTCCGAGCCGAGCAGGCATTTTTGGTGAATAACCGCCCAGATAATGACTCA CGTCCGCTCTTGGACTACGAAACCCTTACTTGGTGGTTTGACGTCGAATCTCGTGTGCGACGCGTGATCTCGTTG GACCAGGCTCTCAATTTCGATGACGTTTGTTTCAAGCCGACTGGAGAAGCTTGTGTCGTGCAATCCTTCACTGGG TATTTCGGCGGTTCCGTCTCAAACCTTGACCCAGATACATGGAAGGACAGACTTAGCCACTGCACAAAGTCGCCT GGCGACCCTAGCTGTCTCCCCGACTTCTCGCAGCCCCTCAAGCCCGAAATGATTCTTGGTGGATATGAAGACACA GGGAATGTTCTGGATGCCCAGGCACTCATTGTGACCTGGGTGGTAAATAATTACGACCAGGGAACAGAAGAAGAA GCAAAAGCCATTGACTGGGAGAACACTTTCCAGGCCGTTCTCGGGGTAGTCCAAGAAGAGGCTGCCGAGCGAGGC CTTCGCGTATCTTTTAATTCCGAGGTCAGCTTGGAACAGGAACTGAACAAGTCTACCAACACAGATGCGAAGATT GTTGTCATCAGTTACCTGATCATGTTCTTCTACGTCTCAATGGCCCTGGGCTCGGTCACAGTTACCTGGAGGTCT CTGCTGACCAATCCGTCCAATGCTCTTGTTCAGTCTAAATTTACACTGGGGATCGTCGGGATCATCATTGTCCTG ATGTCTGTTTCTGCATCGGTCGGACTGTTCTCGGCAGCGGGCGTCAAGGTGACCTTGATCATTGCTGAAGTAATT CCATTCTTGGTCCTGGCAGTCGGTGTAGACAACATTTTCTTGATCGTCCACGAATTCGAGCGAGTCAATATCAGC CATCCCGATGAAGAAATCGACGAGCGAGTTGCCCGTGCGGTTGGTCGAATCGGACCTAGCATCTTCCTGTCTGCT CTGACGGAGACAGTAGCCTTTGCCCTGGGCATCTTTGTTGGTATGCCCGCTGTCAAGAATTTTGCCGCATACGCC GCTGGTGCTGTCTTCATTAACGCCATCCTGCAAATCACCATGTTCATCTCCGTCTTGGCTCTGAACCAGAGACGG GTGCAGAGTCTCCGTGCGGACTGTATCCCTTGTCTTACTGTACGCAAAGCAAATTCGTTCGGCTTCCCTGGGGAG AACTACGACGGCCAGGAAGCAGAGAGCACTTTGCAGGTCTTCATTCGTCGGGTCTATGCGCCTTTCCTCCTGGAT CGTCGGGTGAAAGTTGGCGTTGTTATATTTTTCTTGGGTCTTTTGACTGCCGGTCTAGCCTTCATCCCCGAGGTT CCTCTTGGGTTAGATCAGCGTATCGCGCTCCCTAGCGACTCGTATCTGATTTCGTATTTCAACGACCTAGATTCA TACTTTGACACAGGGCCTCCGGTCTATTTCGTGACTCGGAATGTGAATGTTACCGAACGAAGCCACCAACAACAG CTCTGTGGACGGTTCACCACTTGCGAGGAGTATTCACTTCCCTTTATTCTTGAGCAAGAGTCTAAGCGTCCGAAT GTTTCTTATCTTGCAGGCTCTGCCGCCAGCTGGATTGATGATTTCTTCTATTGGCTGAACCCCCAGCAAGACTGT TGCAAAGAAAACGGCAAGCTTTGTTTTGAGGACCGCGTTCCTGCCTGGAACATCTCTCTTTCGGGAATGCCGGAA GGATCTGAATTTGTCCATTACGCCCAAAAATGGATCGATGCTCCCACCGATGCATCCTGCCCCCTCGGTGGTAAA GCGCCCTACAGCAATGCTTTGGTCATTGATGACAAGTATAAAACGATCAACGCCAGTCATTTCCGTACTAGCCAC ACGCCTCTTCGGAGCCAGAATGAATTTATCGAGGCATATATTGCAGCTCGCCGGATTGCAGATGACATCTCACGG GAACATGATATCGACGTCTTCCCATATTCCAAATTCTACATCTTCTTTGATCAATACGTTTCCATTGTGCGACTT ACTGGTACCCTCCTTGGGTCGGCCGTGGCCATCATCTTCGTCTTGACCTCTGTGATATTGGGGTCTATAGCCACG GGCGCTGTCATTACAACCACAGTGGTTATGATAGTGGTCGATATCATTGGCACTATGGCGATCGCTGGCGTCTCC TTGAATGCGGTATCTCTTGTCAACTTGGTCATTTGTGTCGGCATTGGTGTTGAGTTCTGTGCTCATATTGCCCGA GCATTCATGTTCCCCGCTCGACCCATCATGGATAAGGTGCCCGCCGAATTCCGTGGTAAGGACGCTCGAGCATGG GCGGCCTTGGTCAATGTTGGTGGGACTGTCTTCAGTGGTATTACCGTGACAAAACTTCTCGGGGTTTGCGTCCTG GCGTTCACTCGAAGCAAGATCTTCGAGATCTACTACTTCCGGGTTTGGCTAGCCCTGGTGATTTTTGCTGCTACG CATGCTCTCATCTTCTTACCAGTGGCTCTCAGCTACTTTGGCGGCGGTGGCTACTTTGACCCTGCCTCCGAAGGT GGCCTAGAGGCCAATCTCGCTTCACGTGGCTACCGCTCATCGCTACTCCATGATGAATATGAGTCTGATGAATAT TAA |
| Transcript | >Pro_DTO377G3_2|g9087.t1 ATGCGGTTGCCTAGGGCTCTCGCCCTGATCGTTGGGCTGGGCTCTTTTGCACCTACCCTTGTCGGTGCACAGGGC GAAACTAAAATCCACGAAAAGGGCCGTTGTGCTATTCGAGGTCATTGTGGAAAGCAATCCATTTTTGGAGGTGAA CTACCCTGTCCAGATAATGACCTGGCGCAACAACCAGAAGACGCAGTACGCCAAAAGTTGGTAAATCTGTGTGGC AGCAAATGGAGCGAAGGGCCGGTCTGTTGTCGAGATGAACAGATCGATGCGCTTTCCAGTAACCTCAAACTAGCA GAGGGAATTATCGCGTCCTGCCCTGCCTGCCGAGACAACTTCTTCAACATATTCTGTACCTTTACATGCTCCCCC GATCAATCTCTTTTCATCAATGTCACCAAAACAGAAGAAAACAGATCTGGTAAAAGACTTGTGACCGAGTTGGAC AATATTTGGTCCGAGGAGTACCAGAACGGCTTCTACGATAGCTGCAAGAACGTAAAGAACGGTGCCTCGGGCGGG AAAGCCATTGACTTCATCGGCGGTGGTGCGAAAGACGCTCCCCATTTCATGAAGTTTTTAGGTGATAAGAAGTTT CTCGGGAGCCCGTTCCAGATTAACTATCACACAGAGCCCACTGGGCCTGACCCGCAAGGAATGAAGGCTTTGTCA ATAAAGCCGAAAGCCTGCAATGACGAGGACAAATCATTCCGATGTTCTTGTGTCGACTGCCCGGAAGTGTGTCCG GAGTTGCCTGCCATCTCCCCCCACAAGATATGTCATGTAGGACTTCTACCATGTCTATCGTTTGCCGTCATTCTC GTTTATTCCGTCTTTCTATTATTTGTCATTGCTCTCGCGAGCTATGTCACATACAAGGAACGCCGTTTCCGCAAA CCAGAGCGGGTGCGGTTGCTACAAGATCCCACGCCCAGCGATGACGAAGATGAAGGGGAAGTCATGCACCGTGGA GGATATATGGAAAGATCACATGGAGTATACAAGCTCAACTCTGTGTTGTCAGCTATGTTCTATCGAATCGGTGGT GCTTGTGCGCGGTTCCCAGCAATAACAATATTCTCCAGCGTCACCGGAGTGGTGCTGCTGAGCCTAGGGTGGCTA AATTTCACCGTTGAAACGGATCCGGTGCAACTCTGGGTGAGTCCGTCATCTGCGGCCGCCCAGGAGAAGGATTTC TTCGATCAGAGCTTTGGTCCATTCTTCCGAGCCGAGCAGGCATTTTTGGTGAATAACCGCCCAGATAATGACTCA CGTCCGCTCTTGGACTACGAAACCCTTACTTGGTGGTTTGACGTCGAATCTCGTGTGCGACGCGTGATCTCGTTG GACCAGGCTCTCAATTTCGATGACGTTTGTTTCAAGCCGACTGGAGAAGCTTGTGTCGTGCAATCCTTCACTGGG TATTTCGGCGGTTCCGTCTCAAACCTTGACCCAGATACATGGAAGGACAGACTTAGCCACTGCACAAAGTCGCCT GGCGACCCTAGCTGTCTCCCCGACTTCTCGCAGCCCCTCAAGCCCGAAATGATTCTTGGTGGATATGAAGACACA GGGAATGTTCTGGATGCCCAGGCACTCATTGTGACCTGGGTGGTAAATAATTACGACCAGGGAACAGAAGAAGAA GCAAAAGCCATTGACTGGGAGAACACTTTCCAGGCCGTTCTCGGGGTAGTCCAAGAAGAGGCTGCCGAGCGAGGC CTTCGCGTATCTTTTAATTCCGAGGTCAGCTTGGAACAGGAACTGAACAAGTCTACCAACACAGATGCGAAGATT GTTGTCATCAGTTACCTGATCATGTTCTTCTACGTCTCAATGGCCCTGGGCTCGGTCACAGTTACCTGGAGGTCT CTGCTGACCAATCCGTCCAATGCTCTTGTTCAGTCTAAATTTACACTGGGGATCGTCGGGATCATCATTGTCCTG ATGTCTGTTTCTGCATCGGTCGGACTGTTCTCGGCAGCGGGCGTCAAGGTGACCTTGATCATTGCTGAAGTAATT CCATTCTTGGTCCTGGCAGTCGGTGTAGACAACATTTTCTTGATCGTCCACGAATTCGAGCGAGTCAATATCAGC CATCCCGATGAAGAAATCGACGAGCGAGTTGCCCGTGCGGTTGGTCGAATCGGACCTAGCATCTTCCTGTCTGCT CTGACGGAGACAGTAGCCTTTGCCCTGGGCATCTTTGTTGGTATGCCCGCTGTCAAGAATTTTGCCGCATACGCC GCTGGTGCTGTCTTCATTAACGCCATCCTGCAAATCACCATGTTCATCTCCGTCTTGGCTCTGAACCAGAGACGG GTGCAGAGTCTCCGTGCGGACTGTATCCCTTGTCTTACTGTACGCAAAGCAAATTCGTTCGGCTTCCCTGGGGAG AACTACGACGGCCAGGAAGCAGAGAGCACTTTGCAGGTCTTCATTCGTCGGGTCTATGCGCCTTTCCTCCTGGAT CGTCGGGTGAAAGTTGGCGTTGTTATATTTTTCTTGGGTCTTTTGACTGCCGGTCTAGCCTTCATCCCCGAGGTT CCTCTTGGGTTAGATCAGCGTATCGCGCTCCCTAGCGACTCGTATCTGATTTCGTATTTCAACGACCTAGATTCA TACTTTGACACAGGGCCTCCGGTCTATTTCGTGACTCGGAATGTGAATGTTACCGAACGAAGCCACCAACAACAG CTCTGTGGACGGTTCACCACTTGCGAGGAGTATTCACTTCCCTTTATTCTTGAGCAAGAGTCTAAGCGTCCGAAT GTTTCTTATCTTGCAGGCTCTGCCGCCAGCTGGATTGATGATTTCTTCTATTGGCTGAACCCCCAGCAAGACTGT TGCAAAGAAAACGGCAAGCTTTGTTTTGAGGACCGCGTTCCTGCCTGGAACATCTCTCTTTCGGGAATGCCGGAA GGATCTGAATTTGTCCATTACGCCCAAAAATGGATCGATGCTCCCACCGATGCATCCTGCCCCCTCGGTGGTAAA GCGCCCTACAGCAATGCTTTGGTCATTGATGACAAGTATAAAACGATCAACGCCAGTCATTTCCGTACTAGCCAC ACGCCTCTTCGGAGCCAGAATGAATTTATCGAGGCATATATTGCAGCTCGCCGGATTGCAGATGACATCTCACGG GAACATGATATCGACGTCTTCCCATATTCCAAATTCTACATCTTCTTTGATCAATACGTTTCCATTGTGCGACTT ACTGGTACCCTCCTTGGGTCGGCCGTGGCCATCATCTTCGTCTTGACCTCTGTGATATTGGGGTCTATAGCCACG GGCGCTGTCATTACAACCACAGTGGTTATGATAGTGGTCGATATCATTGGCACTATGGCGATCGCTGGCGTCTCC TTGAATGCGGTATCTCTTGTCAACTTGGTCATTTGTGTCGGCATTGGTGTTGAGTTCTGTGCTCATATTGCCCGA GCATTCATGTTCCCCGCTCGACCCATCATGGATAAGGTGCCCGCCGAATTCCGTGGTAAGGACGCTCGAGCATGG GCGGCCTTGGTCAATGTTGGTGGGACTGTCTTCAGTGGTATTACCGTGACAAAACTTCTCGGGGTTTGCGTCCTG GCGTTCACTCGAAGCAAGATCTTCGAGATCTACTACTTCCGGGTTTGGCTAGCCCTGGTGATTTTTGCTGCTACG CATGCTCTCATCTTCTTACCAGTGGCTCTCAGCTACTTTGGCGGCGGTGGCTACTTTGACCCTGCCTCCGAAGGT GGCCTAGAGGCCAATCTCGCTTCACGTGGCTACCGCTCATCGCTACTCCATGATGAATATGAGTCTGATGAATAT TAA |
| Gene | >Pro_DTO377G3_2|g9087.t1 ATGCGGTTGCCTAGGGCTCTCGCCCTGATCGTTGGGCTGGGCTCTTTTGCACCTACCCTTGTCGGTGCACAGGGC GAAACTAAAATCCACGAAAAGGGCCGTTGTGCTATTCGAGGTCATTGTGGAAAGCAATCCATTTTTGGAGGTGAA CTACCCTGTCCAGATAATGACCTGGCGCAACAACCAGAAGACGCAGTACGCCAAAAGTTGGTAAATCTGTGTGGC AGCAAATGGAGCGAAGGGCCGGTCTGTTGTCGAGATGAACAGGTGAGAGATCCCGGCCTCTGTTTTCGTCAACGA TAGTATCACTATATTTATAATTCTATCATGCTGATAACCCATAGATCGATGCGCTTTCCAGTAACCTCAAACTAG CAGAGGGAATTATCGCGTCCTGCCCTGCCTGCCGAGACAACTTCTTCAACATATTCTGTACCTTTACATGCTCCC CCGATCAATCTCTTTTCATCAATGTCACCAAAACAGAAGAAAACAGATCTGGTAAAAGACTTGTGACCGAGTTGG ACAATATTTGGTCCGAGGAGTACCAGAACGGCTTCTACGATAGCTGCAAGAACGTAAAGAACGGTGCCTCGGGCG GGAAAGCCATTGACTTCATCGGCGGTGGTGCGAAAGACGCTCCCCATTTCATGAAGTTTTTAGGTGATAAGAAGT TTCTCGGGAGCCCGTTCCAGATTAACTATCACACAGAGCCCACTGGGCCTGACCCGCAAGGAATGAAGGCTTTGT CAATAAAGCCGAAAGCCTGCAATGACGAGGACAAATCATTCCGATGTTCTTGTGTCGACTGCCCGGAAGTGTGTC CGGAGTTGCCTGCCATCTCCCCCCACAAGATATGTCATGTAGGACTTCTACCATGTCTATCGTTTGCCGTCATTC TCGTTTATTCCGTCTTTCTATTATTTGTCATTGCTCTCGCGAGCTATGTCACATACAAGGAACGCCGTTTCCGCA AACCAGAGCGGGTGCGGTTGCTACAAGATCCCACGCCCAGCGATGACGAAGATGAAGGGGAAGTCATGCACCGTG GAGGATATATGGAAAGATCACATGGAGTATACAAGCTCAACTCTGTGTTGTCAGCTATGTTCTATCGAATCGGTG GTGCTTGTGCGCGGTTCCCAGCAATAACAATATTCTCCAGCGTCACCGGAGTGGTGCTGCTGAGCCTAGGGTGGC TAAATTTCACCGTTGAAACGGATCCGGTGCAACTCTGGGTGAGTCCGTCATCTGCGGCCGCCCAGGAGAAGGATT TCTTCGATCAGAGCTTTGGTCCATTCTTCCGAGCCGAGCAGGCATTTTTGGTGAATAACCGCCCAGATAATGACT CACGTCCGCTCTTGGACTACGAAACCCTTACTTGGTGGTTTGACGTCGAATCTCGTGTGCGACGCGTGATCTCGT TGGACCAGGCTCTCAATTTCGATGACGTTTGTTTCAAGCCGACTGGAGAAGCTTGTGTCGTGCAATCCTTCACTG GGTATTTCGGCGGTTCCGTCTCAAACCTTGACCCAGATACATGGAAGGACAGACTTAGCCACTGCACAAAGTCGC CTGGCGACCCTAGCTGTCTCCCCGACTTCTCGCAGCCCCTCAAGCCCGAAATGATTCTTGGTGGATATGAAGACA CAGGGAATGTTCTGGATGCCCAGGCACTCATTGTGACCTGGGTGGTAAATAATTACGACCAGGGAACAGAAGAAG AAGCAAAAGCCATTGACTGGGAGAACACTTTCCAGGCCGTTCTCGGGGTAGTCCAAGAAGAGGCTGCCGAGCGAG GCCTTCGCGTATCTTTTAATTCCGAGGTCAGCTTGGAACAGGAACTGAACAAGTCTACCAACACAGATGCGAAGA TTGTTGTCATCAGTTACCTGATCATGTTCTTCTACGTCTCAATGGCCCTGGGCTCGGTCACAGTTACCTGGAGGT CTCTGCTGACCAATCCGTCCAATGCTCTTGTTCAGTCTAAATTTACACTGGGGATCGTCGGGATCATCATTGTCC TGATGTCTGTTTCTGCATCGGTCGGACTGTTCTCGGCAGCGGGCGTCAAGGTGACCTTGATCATTGCTGAAGTAA TTCCATTCTTGGTCCTGGCAGTCGGTGTAGACAACATTTTCTTGATCGTCCACGAATTCGAGCGAGTCAATATCA GCCATCCCGATGAAGAAATCGACGAGCGAGTTGCCCGTGCGGTTGGTCGAATCGGACCTAGCATCTTCCTGTCTG CTCTGACGGAGACAGTAGCCTTTGCCCTGGGCATCTTTGTTGGTATGCCCGCTGTCAAGAATTTTGCCGCATACG CCGCTGGTGCTGTCTTCATTAACGCCATCCTGCAAATCACCATGTTCATCTCCGTCTTGGCTCTGAACCAGAGAC GGGTGCAGAGTCTCCGTGCGGACTGTATCCCTTGTCTTACTGTACGCAAAGCAAATTCGTTCGGCTTCCCTGGGG AGAACTACGACGGCCAGGAAGCAGAGAGCACTTTGCAGGTCTTCATTCGTCGGGTCTATGCGCCTTTCCTCCTGG ATCGTCGGGTGAAAGTTGGCGTTGTTATATTTTTCTTGGGTCTTTTGACTGCCGGTCTAGCCTTCATCCCCGAGG TTCCTCTTGGGTTAGATCAGCGTATCGCGCTCCCTAGCGACTCGTATCTGATTTCGTATTTCAACGACCTAGATT CATACTTTGACACAGGGCCTCCGGTCTATTTCGTGACTCGGAATGTGAATGTTACCGAACGAAGCCACCAACAAC AGCTCTGTGGACGGTTCACCACTTGCGAGGAGTATTCACTTCCCTTTATTCTTGAGCAAGAGTCTAAGCGTCCGA ATGTTTCTTATCTTGCAGGCTCTGCCGCCAGCTGGATTGATGATTTCTTCTATTGGCTGAACCCCCAGCAAGACT GTTGCAAAGAAAACGGCAAGCTTTGTTTTGAGGACCGCGTTCCTGCCTGGAACATCTCTCTTTCGGGAATGCCGG AAGGATCTGAATTTGTCCATTACGCCCAAAAATGGATCGATGCTCCCACCGATGCATCCTGCCCCCTCGGTGGTA AAGCGCCCTACAGCAATGCTTTGGTCATTGATGACAAGTATAAAACGATCAACGCCAGTCATTTCCGTACTAGCC ACACGCCTCTTCGGAGCCAGAATGAATTTATCGAGGCATATATTGCAGCTCGCCGGATTGCAGATGACATCTCAC GGGAACATGATATCGACGTCTTCCCATATTCCAAATTCTACATCTTCTTTGATCAATACGTTTCCATTGTGCGAC TTACTGGTACCCTCCTTGGGTCGGCCGTGGCCATCATCTTCGTCTTGACCTCTGTGATATTGGGGTCTATAGCCA CGGGCGCTGTCATTACAACCACAGTGGTTATGATAGTGGTCGATATCATTGGCACTATGGCGATCGCTGGCGTCT CCTTGAATGCGGTATCTCTTGTCAACTTGGTCATTTGTGTCGGCATTGGTGTTGAGTTCTGTGCTCATATTGCCC GAGCATTCATGTTCCCCGCTCGACCCATCATGGATAAGGTGCCCGCCGAATTCCGTGGTAAGGACGCTCGAGCAT GGGCGGCCTTGGTCAATGTTGGTGGGACTGTCTTCAGTGGTATTACCGTGACAAAACTTCTCGGGGTTTGCGTCC TGGCGTTCACTCGAAGCAAGATCTTCGAGATCTACTACTTCCGGGTTTGGCTAGCCCTGGTGATTTTTGCTGCTA CGCATGCTCTCATCTTCTTACCAGTGGCTCTCAGCTACTTTGGCGGCGGTGGTACGTGCAAATTGACCCATCGCT ATTGAATAAGGAGAACTCTACTGACTTATTTAGGCTACTTTGACCCTGCCTCCGAAGGTGGCCTAGAGGCCAATC TCGCTTCACGTGGCTACCGCTCATCGCTACTCCATGATGAATATGAGTCTGATGAATATTAA |