Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g8740.t1
Gene name
Location	scaffold_36:172676..176551
Strand	-
Gene length (bp)	3875
Transcript length (bp)	3585
Coding sequence length (bp)	3585
Protein length (aa)	1195

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00620	RhoGAP	RhoGAP domain	8.6E-33	864	1013
PF00412	LIM	LIM domain	1.4E-08	107	166
PF00412	LIM	LIM domain	5.8E-11	171	226

GO

GO Term	Description	Terminal node
GO:0007165	signal transduction	Yes
GO:0008150	biological_process	No
GO:0050789	regulation of biological process	No
GO:0009987	cellular process	No
GO:0050794	regulation of cellular process	No
GO:0065007	biological regulation	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g8740.t1 MPPGGLPASLVAGNPSGRPTVDTSGYGASYTKNTPTSPEDSLIPFESPSTRTAGPSPISPANQEDGGRSGRGLGP DQAGFRDRSAPRDRSRVNGRQNKSPGGSSRLCQKCGETLTGQFVRALGGTFHLECFKCEDCGEIVASKFFPVDSE DSSCQFPLCETDYFRRLGLLCHECGGALRGSYITALDRKYHIEHFTCSVCPTVFGAQDSYYEHESKVYCHFHYST QFAQRCHGCHTAILKQFVEIFRNGQNQHWHPECYMIHKFWNVRLSPAGQTWEPPPVDEDASEDERKHIRDEEDLM EEKVFNIWNTLSTFEESSAACISDMLLHVSNGAYIDGVLVAKRFIEHVEILFGAVDQLADYIKSHELKELSYGRE AKLLCKKIVAFFALLSKTQETGVRKLGVTQELLSLVTGLAHYLKLLIRIGLQGALKLEREKSAPDGLQNFLERLR DLESLADEDDDTPVDLMAGVEGLADQLSDCCIACKEPIDDECVQLGQSRWHIKPPHLSCKSCEKDLTADFQDALW SGSEEKVYCGACARQMKLGPTVKGGFTPVSKLQQFVFLLKVALARLLAVLRSGGTLPHTSDDPNLNDYDNNDGYR VTSQVRRANTRSQSYGGSSRDGLEETSLEQTVGEMRRLRSIRNERTLSTTYKRARASRIIDGPEGRSARPGSSGN DGGDPRSHGFQIVEERDANGEPVTDLTFGAQDALTLDDIPRIVAAEQAKEQRPNAYRHAGTKLIGGTEMPRYNQG HQRGVSCGNMEAMMEPTRTKRYFSELTALEYFIVRHVAVLQMEPLVEGYFTMEELLSLIESRKPTIWNIFGRAFK DNKKGNKKKGVFGVSLDYLVEKEGTESSHGVGPGALRIPTLVDDSVCAMRQMDMSVEGVFRKNGNIRRLKDTAEL IDTKYEQVDLTKETPVQIAALLKKFLREMPDPLLTFKLHRLFVISQKMDDTEKQRRLLHLTCCLLPKAHRDTMEV LFAFLNWTSSFSHVDEESGSKMDVHNLATVITPNILYPNVKNSTVEESFLAIEAVNALITYNDAFCEIPEDLQSV LGDPTLFRENAEVTTKEILKRYGDIGRGSFAQRPENGGETFTITTPNRNNSTPASARIETDPSQDAAWQMQSSVR HVVGPSGHAHSSSTNIQAGLDFGPPPPAAYRRDRSTSNGSQPIAGAPDGQPSNVAYRPRPNAGAMGVTG*
Coding	>Pro_DTO377G3_2|g8740.t1 ATGCCCCCCGGTGGACTCCCAGCCAGCCTGGTCGCAGGTAATCCCAGCGGCCGTCCCACCGTCGACACCTCTGGC TACGGGGCTAGCTATACGAAAAACACACCCACATCTCCCGAAGATAGTTTGATTCCATTCGAGTCACCGTCAACA CGAACGGCAGGCCCAAGCCCCATCAGTCCGGCGAACCAGGAGGATGGTGGCCGCTCGGGTCGTGGTCTGGGTCCT GACCAGGCCGGCTTCCGCGACCGCTCCGCGCCCCGAGATCGCTCGCGAGTAAACGGGCGTCAGAACAAGTCTCCA GGTGGTTCATCGCGACTGTGTCAAAAGTGCGGCGAAACTCTCACTGGCCAGTTTGTTCGAGCATTAGGGGGAACT TTTCATCTAGAGTGTTTCAAGTGCGAAGACTGTGGCGAGATCGTTGCTTCGAAGTTTTTCCCCGTCGATTCAGAA GATTCAAGCTGCCAGTTTCCGCTTTGTGAAACCGATTACTTTAGACGACTGGGTCTCCTATGCCATGAGTGCGGC GGCGCACTACGCGGATCATACATTACAGCGTTGGACCGGAAGTATCATATTGAACACTTCACCTGTTCCGTTTGC CCGACCGTCTTTGGTGCGCAGGACTCTTACTATGAACACGAGAGCAAGGTCTACTGCCACTTTCACTACTCAACA CAGTTTGCCCAGCGGTGCCATGGATGTCACACAGCAATCCTGAAACAGTTTGTCGAAATCTTCCGCAACGGTCAA AATCAACATTGGCACCCCGAATGTTATATGATTCACAAGTTCTGGAATGTCCGGTTATCCCCTGCCGGTCAAACA TGGGAGCCTCCGCCCGTGGATGAGGATGCCAGCGAAGATGAGCGCAAGCATATTCGCGACGAAGAAGATTTAATG GAAGAAAAGGTCTTCAATATTTGGAACACCCTTTCTACCTTTGAAGAATCATCCGCCGCTTGCATCTCAGACATG CTACTTCATGTGAGTAACGGCGCTTACATCGATGGTGTTCTCGTAGCAAAGCGCTTCATCGAACATGTGGAAATC CTCTTCGGTGCAGTCGATCAGTTGGCAGACTACATCAAATCCCACGAGTTAAAAGAACTTTCCTATGGCCGCGAA GCCAAACTTCTTTGCAAAAAGATTGTCGCTTTCTTCGCCCTTCTATCGAAAACCCAGGAAACTGGGGTACGCAAA CTTGGCGTCACCCAGGAACTCCTGTCTCTGGTGACTGGTCTCGCTCATTACCTCAAACTCCTTATCCGCATCGGT CTACAAGGTGCACTGAAACTTGAACGCGAGAAGTCTGCGCCAGATGGTTTACAAAACTTCCTAGAGCGTCTCCGT GATCTGGAGTCATTAGCAGACGAGGATGACGATACGCCAGTCGACCTGATGGCTGGAGTGGAAGGCTTGGCCGAT CAACTTTCAGATTGTTGCATTGCCTGTAAAGAACCAATTGACGACGAATGTGTTCAGTTGGGACAGAGTCGTTGG CACATCAAGCCGCCTCATCTTTCATGCAAATCATGTGAGAAGGACTTAACCGCTGATTTCCAAGACGCATTGTGG AGCGGCAGCGAGGAAAAAGTCTACTGCGGCGCTTGCGCCCGCCAGATGAAACTTGGCCCCACCGTGAAGGGTGGT TTCACTCCAGTCTCAAAATTGCAGCAATTCGTTTTCTTGCTGAAAGTGGCACTCGCACGGCTTCTCGCCGTACTG CGATCCGGGGGAACCTTGCCTCATACCTCAGACGACCCCAACCTTAATGATTACGACAACAATGACGGCTATCGA GTCACTTCCCAGGTTCGCCGGGCGAACACACGCTCCCAGTCATATGGCGGTTCCTCGCGAGATGGCCTCGAAGAA ACATCGCTCGAGCAGACCGTTGGCGAGATGCGTCGGCTGCGCTCTATTCGAAATGAGCGAACCCTATCCACAACG TACAAACGAGCCCGCGCATCCAGAATCATTGATGGACCAGAAGGCAGAAGTGCTCGACCAGGGTCATCTGGCAAT GATGGCGGTGACCCGAGGAGCCACGGTTTCCAGATTGTCGAAGAACGGGATGCCAATGGCGAACCTGTTACTGAT CTGACTTTCGGGGCTCAGGATGCTTTGACGCTAGATGACATCCCCCGCATTGTTGCGGCCGAGCAAGCCAAGGAG CAGCGACCTAATGCCTACAGGCATGCTGGTACAAAACTCATTGGGGGGACCGAGATGCCCAGATATAACCAGGGT CACCAGCGGGGAGTATCGTGTGGAAATATGGAAGCGATGATGGAGCCAACCCGAACCAAGCGGTACTTCTCAGAA CTAACTGCTTTGGAATATTTCATCGTTCGCCACGTTGCTGTACTCCAAATGGAACCGTTAGTCGAGGGCTATTTC ACCATGGAAGAGCTCCTTTCCCTTATCGAGTCGCGCAAGCCTACCATATGGAACATCTTTGGCCGTGCCTTCAAG GATAACAAGAAGGGTAATAAGAAGAAGGGTGTCTTTGGTGTCAGTCTAGACTATCTGGTCGAGAAGGAGGGCACA GAGTCAAGTCACGGTGTTGGTCCTGGTGCGCTCCGCATCCCGACGCTAGTTGATGATTCTGTCTGCGCTATGCGG CAGATGGACATGTCTGTGGAGGGTGTCTTCCGAAAGAACGGAAACATCCGCCGATTGAAGGACACCGCAGAGCTA ATTGACACCAAGTACGAGCAAGTTGATCTGACAAAGGAAACTCCCGTGCAGATTGCAGCTCTTTTGAAGAAGTTC CTCCGTGAAATGCCCGATCCTCTCTTGACTTTCAAGCTGCATAGACTGTTTGTCATCTCACAAAAAATGGATGAC ACAGAGAAACAGAGGCGACTACTTCACTTGACATGCTGTCTGCTTCCCAAGGCCCATCGTGATACGATGGAAGTC CTGTTTGCCTTCTTAAACTGGACTTCATCCTTCTCACATGTGGATGAAGAGTCTGGAAGCAAGATGGACGTCCAT AATCTTGCGACTGTGATCACGCCCAATATCCTCTACCCCAATGTCAAAAACAGCACAGTGGAGGAGAGCTTCTTG GCCATCGAGGCTGTTAATGCCCTGATCACGTACAACGATGCATTCTGCGAAATTCCAGAAGACCTACAATCGGTC TTGGGTGATCCAACTCTCTTTAGGGAGAATGCCGAAGTGACAACCAAGGAAATCCTTAAAAGATATGGCGACATC GGTCGAGGCAGCTTTGCACAGCGACCGGAGAACGGTGGCGAGACATTCACCATCACCACCCCCAACCGAAACAAT AGCACTCCAGCTTCCGCGCGTATTGAGACTGATCCATCTCAGGATGCAGCTTGGCAGATGCAAAGCTCGGTTCGC CATGTGGTCGGGCCCAGCGGACACGCACACTCGTCCAGCACTAACATCCAGGCCGGACTTGATTTCGGTCCTCCT CCCCCAGCAGCGTATCGCCGTGACCGTAGCACCAGCAACGGAAGCCAGCCAATCGCAGGGGCACCTGATGGTCAA CCATCCAATGTGGCTTATAGGCCGCGCCCGAATGCGGGTGCCATGGGTGTTACTGGGTAG
Transcript	>Pro_DTO377G3_2|g8740.t1 ATGCCCCCCGGTGGACTCCCAGCCAGCCTGGTCGCAGGTAATCCCAGCGGCCGTCCCACCGTCGACACCTCTGGC TACGGGGCTAGCTATACGAAAAACACACCCACATCTCCCGAAGATAGTTTGATTCCATTCGAGTCACCGTCAACA CGAACGGCAGGCCCAAGCCCCATCAGTCCGGCGAACCAGGAGGATGGTGGCCGCTCGGGTCGTGGTCTGGGTCCT GACCAGGCCGGCTTCCGCGACCGCTCCGCGCCCCGAGATCGCTCGCGAGTAAACGGGCGTCAGAACAAGTCTCCA GGTGGTTCATCGCGACTGTGTCAAAAGTGCGGCGAAACTCTCACTGGCCAGTTTGTTCGAGCATTAGGGGGAACT TTTCATCTAGAGTGTTTCAAGTGCGAAGACTGTGGCGAGATCGTTGCTTCGAAGTTTTTCCCCGTCGATTCAGAA GATTCAAGCTGCCAGTTTCCGCTTTGTGAAACCGATTACTTTAGACGACTGGGTCTCCTATGCCATGAGTGCGGC GGCGCACTACGCGGATCATACATTACAGCGTTGGACCGGAAGTATCATATTGAACACTTCACCTGTTCCGTTTGC CCGACCGTCTTTGGTGCGCAGGACTCTTACTATGAACACGAGAGCAAGGTCTACTGCCACTTTCACTACTCAACA CAGTTTGCCCAGCGGTGCCATGGATGTCACACAGCAATCCTGAAACAGTTTGTCGAAATCTTCCGCAACGGTCAA AATCAACATTGGCACCCCGAATGTTATATGATTCACAAGTTCTGGAATGTCCGGTTATCCCCTGCCGGTCAAACA TGGGAGCCTCCGCCCGTGGATGAGGATGCCAGCGAAGATGAGCGCAAGCATATTCGCGACGAAGAAGATTTAATG GAAGAAAAGGTCTTCAATATTTGGAACACCCTTTCTACCTTTGAAGAATCATCCGCCGCTTGCATCTCAGACATG CTACTTCATGTGAGTAACGGCGCTTACATCGATGGTGTTCTCGTAGCAAAGCGCTTCATCGAACATGTGGAAATC CTCTTCGGTGCAGTCGATCAGTTGGCAGACTACATCAAATCCCACGAGTTAAAAGAACTTTCCTATGGCCGCGAA GCCAAACTTCTTTGCAAAAAGATTGTCGCTTTCTTCGCCCTTCTATCGAAAACCCAGGAAACTGGGGTACGCAAA CTTGGCGTCACCCAGGAACTCCTGTCTCTGGTGACTGGTCTCGCTCATTACCTCAAACTCCTTATCCGCATCGGT CTACAAGGTGCACTGAAACTTGAACGCGAGAAGTCTGCGCCAGATGGTTTACAAAACTTCCTAGAGCGTCTCCGT GATCTGGAGTCATTAGCAGACGAGGATGACGATACGCCAGTCGACCTGATGGCTGGAGTGGAAGGCTTGGCCGAT CAACTTTCAGATTGTTGCATTGCCTGTAAAGAACCAATTGACGACGAATGTGTTCAGTTGGGACAGAGTCGTTGG CACATCAAGCCGCCTCATCTTTCATGCAAATCATGTGAGAAGGACTTAACCGCTGATTTCCAAGACGCATTGTGG AGCGGCAGCGAGGAAAAAGTCTACTGCGGCGCTTGCGCCCGCCAGATGAAACTTGGCCCCACCGTGAAGGGTGGT TTCACTCCAGTCTCAAAATTGCAGCAATTCGTTTTCTTGCTGAAAGTGGCACTCGCACGGCTTCTCGCCGTACTG CGATCCGGGGGAACCTTGCCTCATACCTCAGACGACCCCAACCTTAATGATTACGACAACAATGACGGCTATCGA GTCACTTCCCAGGTTCGCCGGGCGAACACACGCTCCCAGTCATATGGCGGTTCCTCGCGAGATGGCCTCGAAGAA ACATCGCTCGAGCAGACCGTTGGCGAGATGCGTCGGCTGCGCTCTATTCGAAATGAGCGAACCCTATCCACAACG TACAAACGAGCCCGCGCATCCAGAATCATTGATGGACCAGAAGGCAGAAGTGCTCGACCAGGGTCATCTGGCAAT GATGGCGGTGACCCGAGGAGCCACGGTTTCCAGATTGTCGAAGAACGGGATGCCAATGGCGAACCTGTTACTGAT CTGACTTTCGGGGCTCAGGATGCTTTGACGCTAGATGACATCCCCCGCATTGTTGCGGCCGAGCAAGCCAAGGAG CAGCGACCTAATGCCTACAGGCATGCTGGTACAAAACTCATTGGGGGGACCGAGATGCCCAGATATAACCAGGGT CACCAGCGGGGAGTATCGTGTGGAAATATGGAAGCGATGATGGAGCCAACCCGAACCAAGCGGTACTTCTCAGAA CTAACTGCTTTGGAATATTTCATCGTTCGCCACGTTGCTGTACTCCAAATGGAACCGTTAGTCGAGGGCTATTTC ACCATGGAAGAGCTCCTTTCCCTTATCGAGTCGCGCAAGCCTACCATATGGAACATCTTTGGCCGTGCCTTCAAG GATAACAAGAAGGGTAATAAGAAGAAGGGTGTCTTTGGTGTCAGTCTAGACTATCTGGTCGAGAAGGAGGGCACA GAGTCAAGTCACGGTGTTGGTCCTGGTGCGCTCCGCATCCCGACGCTAGTTGATGATTCTGTCTGCGCTATGCGG CAGATGGACATGTCTGTGGAGGGTGTCTTCCGAAAGAACGGAAACATCCGCCGATTGAAGGACACCGCAGAGCTA ATTGACACCAAGTACGAGCAAGTTGATCTGACAAAGGAAACTCCCGTGCAGATTGCAGCTCTTTTGAAGAAGTTC CTCCGTGAAATGCCCGATCCTCTCTTGACTTTCAAGCTGCATAGACTGTTTGTCATCTCACAAAAAATGGATGAC ACAGAGAAACAGAGGCGACTACTTCACTTGACATGCTGTCTGCTTCCCAAGGCCCATCGTGATACGATGGAAGTC CTGTTTGCCTTCTTAAACTGGACTTCATCCTTCTCACATGTGGATGAAGAGTCTGGAAGCAAGATGGACGTCCAT AATCTTGCGACTGTGATCACGCCCAATATCCTCTACCCCAATGTCAAAAACAGCACAGTGGAGGAGAGCTTCTTG GCCATCGAGGCTGTTAATGCCCTGATCACGTACAACGATGCATTCTGCGAAATTCCAGAAGACCTACAATCGGTC TTGGGTGATCCAACTCTCTTTAGGGAGAATGCCGAAGTGACAACCAAGGAAATCCTTAAAAGATATGGCGACATC GGTCGAGGCAGCTTTGCACAGCGACCGGAGAACGGTGGCGAGACATTCACCATCACCACCCCCAACCGAAACAAT AGCACTCCAGCTTCCGCGCGTATTGAGACTGATCCATCTCAGGATGCAGCTTGGCAGATGCAAAGCTCGGTTCGC CATGTGGTCGGGCCCAGCGGACACGCACACTCGTCCAGCACTAACATCCAGGCCGGACTTGATTTCGGTCCTCCT CCCCCAGCAGCGTATCGCCGTGACCGTAGCACCAGCAACGGAAGCCAGCCAATCGCAGGGGCACCTGATGGTCAA CCATCCAATGTGGCTTATAGGCCGCGCCCGAATGCGGGTGCCATGGGTGTTACTGGGTAG
Gene	>Pro_DTO377G3_2|g8740.t1 ATGCCCCCCGGTGGACTCCCAGCCAGCCTGGTCGCAGGTAATCCCAGCGGCCGTCCCACCGTCGACACCTCTGGC TACGGGGCTAGCTATACGAAAAACACACCCACATCTCCCGAAGATAGTTTGATTCCATTCGAGTCACCGTCAACA CGAACGGCAGGCCCAAGCCCCATCAGTCCGGCGAACCAGGAGGATGGTGGCCGCTCGGGTCGTGGTCTGGGTCCT GACCAGGCCGGCTTCCGCGACCGCTCCGCGCCCCGAGATCGCTCGCGAGTAAACGGGCGTCAGAACAAGTCTCCA GGTGGTTCATCGCGACTGTGTCAAAAGTGCGGCGAAACTCTCACTGGCCAGTTTGTTCGAGCATTAGGGGGAACT TTTCATCTAGAGTGTTTCAAGTGCGAAGTAAGTTGTTTTTTCTAGCCCGCGTTTTTGGGGTCTTCTCTAACTTCC ATACTCCTCTCAGGACTGTGGCGAGATCGTTGCTTCGAAGTTTTTCCCCGTCGATTCAGAAGATTCAAGCTGCCA GTTTCCGCTTTGTGAAACCGATTACTTTAGACGACTGGGTCTCCTATGCCATGAGTGCGGCGGCGCACTACGCGG ATCATACATTACAGCGTTGGACCGGAAGTATCATATTGAACACTTCACCTGTTCCGTTTGCCCGACCGTCTTTGG TGCGCAGGACTCTTACTATGAACACGAGAGCAAGGTCTACTGCCACTTTCACTACTCAACACAGTTTGCCCAGCG GTGCCATGGATGTCACACAGCAATCCTGAAACAGTTTGTCGAAATCTTCCGCAACGGTCAAAATCAACATTGGCA CCCCGAATGTTATATGATTCACAAGTTCTGGAATGTCCGGTTATCCCCTGCCGGTCAAACATGGGAGCCTCCGCC CGTGGATGAGGATGCCAGCGAAGATGAGCGCAAGCATATTCGCGACGAAGAAGATTTAATGGAAGAAAAGGTCTT CAATATTTGGAACACCCTTTCTACCTTTGAAGAATCATCCGCCGCTTGCATCTCAGACATGCTACTTCATGTGAG TAACGGCGCTTACATCGATGGTGTTCTCGTAGCAAAGCGCTTCATCGAACATGTGGAAATCCTCTTCGGTGCAGT CGATCAGTTGGCAGACTACATCAAATCCCACGAGTTAAAAGGTAAGTCCCGCGCGGCTGGTTTTATATCATCCGG GGCGATCGCTGATCATTCAAAACCAGAACTTTCCTATGGCCGCGAAGCCAAACTTCTTTGCAAAAAGATTGTCGC TTTCTTCGCCCTTCTATCGAAAACCCAGGAAACTGGGGTACGCAAACTTGGCGTCACCCAGGAACTCCTGTCTCT GGTGACTGGTCTCGCTCATTACCTCAAACTCCTTATCCGCATCGGTCTACAAGGTGCACTGAAACTTGAACGCGA GAAGTCTGCGCCAGATGGTTTACAAAACTTCCTAGAGCGTCTCCGTGATCTGGAGTCATTAGCAGACGAGGATGA CGATACGCCAGTCGACCTGATGGCTGGAGTGGAAGGCTTGGCCGATCAACTTTCAGATTGTTGCATTGCCTGTAA AGAACCAATTGACGACGAATGTGTTCAGTTGGGACAGAGTCGTTGGCACATCAAGCCGCCTCATCTTTCATGCAA ATCATGTGAGAAGGACTTAACCGCTGATTTCCAAGACGCATTGTGGAGCGGCAGCGAGGAAAAAGTCTACTGCGG CGCTTGCGCCCGCCAGATGAAACTTGGCCCCACCGTGAAGGGTGGTTTCACTCCAGTCTCAAAATTGCAGCAATT CGTTTTCTTGCTGAAAGTGGCACTCGCACGGCTTCTCGCCGTACTGCGATCCGGGGGAACCTTGCCTCATACCTC AGGTAGGATACTCTTACATTACCCCCATGCCGCCGGCAGTCTGTCTAACTTGATTCGTCCCAGACGACCCCAACC TTAATGATTACGACAACAATGACGGCTATCGAGTCACTTCCCAGGTTCGCCGGGCGAACACACGCTCCCAGTCAT ATGGCGGTTCCTCGCGAGATGGCCTCGAAGAAACATCGCTCGAGCAGACCGTTGGCGAGATGCGTCGGCTGCGCT CTATTCGAAATGAGCGAACCCTATCCACAACGTACAAACGAGCCCGCGCATCCAGAATCATTGATGGACCAGAAG GCAGAAGTGCTCGACCAGGGTCATCTGGCAATGATGGCGGTGACCCGAGGAGCCACGGTTTCCAGATTGTCGAAG AACGGGATGCCAATGGCGAACCTGTTACTGATCTGACTTTCGGGGCTCAGGATGCTTTGACGCTAGATGACATCC CCCGCATTGTTGCGGCCGAGCAAGCCAAGGAGCAGCGACCTAATGCCTACAGGCATGCTGGTACAAAACTCATTG GGGGGACCGAGATGCCCAGATATAACCAGGGTCACCAGCGGGGAGTATCGTGTGGAAATATGGAAGCGATGATGG AGCCAACCCGAACCAAGCGGTACTTCTCAGAACTAACTGCTTTGGAATATTTCATCGTTCGCCACGTTGCTGTAC TCCAAATGGAACCGTTAGTCGAGGGCTATTTCACCATGGAAGAGCTCCTTTCCCTTATCGAGTCGCGCAAGCCTA CCATATGGAACATCTTTGGCCGTGCCTTCAAGGATAACAAGAAGGGTAATAAGAAGAAGGGTGTCTTTGGTGTCA GTCTAGACTATCTGGTCGAGAAGGAGGGCACAGAGTCAAGTCACGGTGTTGGTCCTGGTGCGCTCCGCATCCCGA CGCTAGTTGATGATTCTGTCTGCGCTATGCGGCAGATGGACATGTCTGTGGAGGGTGTCTTCCGAAAGAACGGAA ACATCCGCCGATTGAAGGACACCGCAGAGCTAATTGACACCAAGTACGAGCAAGTTGATCTGACAAAGGAAACTC CCGTGCAGATTGCAGCTCTTTTGAAGAAGTTCCTCCGTGAAATGCCCGATCCTCTCTTGACTTTCAAGCTGCATA GACTGTTTGTCATCTCACAAAGTAAGTTTTGATGTTAGGATTATCGGTCTACAAGTGCAATGCTAACTGTATCGC AGAAATGGATGACACAGAGAAACAGAGGCGACTACTTCACTTGACATGCTGTCTGCTTCCCAAGGCCCATCGTGA TACGATGGAAGTCCTGTTTGCCTTCTTAAACTGGACTTCATCCTTCTCACATGTGGATGAAGAGTCTGGAAGCAA GATGGACGTCCATAATCTTGCGACTGTGATCACGCCCAATATCCTCTACCCCAATGTCAAAAACAGCACAGTGGA GGAGAGCTTCTTGGCCATCGAGGCTGTTAATGCCCTGATCACGTACAACGATGCATTCTGCGAAGTAAATCGCCC AGGTTGAGCTTTTGCTAGGATTGTGCTGACTCTGTTCATAGATTCCAGAAGACCTACAATCGGTCTTGGGTGATC CAACTCTCTTTAGGGAGAATGCCGAAGTGACAACCAAGGAAATCCTTAAAAGATATGGCGACATCGGTCGAGGCA GCTTTGCACAGCGACCGGAGAACGGTGGCGAGACATTCACCATCACCACCCCCAACCGAAACAATAGCACTCCAG CTTCCGCGCGTATTGAGACTGATCCATCTCAGGATGCAGCTTGGCAGATGCAAAGCTCGGTTCGCCATGTGGTCG GGCCCAGCGGACACGCACACTCGTCCAGCACTAACATCCAGGCCGGACTTGATTTCGGTCCTCCTCCCCCAGCAG CGTATCGCCGTGACCGTAGCACCAGCAACGGAAGCCAGCCAATCGCAGGGGCACCTGATGGTCAACCATCCAATG TGGCTTATAGGCCGCGCCCGAATGCGGGTGCCATGGGTGTTACTGGGTAG