Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g8503.t1
Gene name
Location	scaffold_33:238788..242171
Strand	+
Gene length (bp)	3383
Transcript length (bp)	3189
Coding sequence length (bp)	3189
Protein length (aa)	1063

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00133	tRNA-synt_1	tRNA synthetases class I (I, L, M and V)	1.5E-223	113	734
PF08264	Anticodon_1	Anticodon-binding domain of tRNA	3.0E-30	779	926
PF09334	tRNA-synt_1g	tRNA synthetases class I (M)	4.0E-07	144	293
PF13603	tRNA-synt_1_2	Leucyl-tRNA synthetase, Domain 2	5.4E-06	361	419

GO

GO Term	Description	Terminal node
GO:0005524	ATP binding	Yes
GO:0002161	aminoacyl-tRNA editing activity	Yes
GO:0006418	tRNA aminoacylation for protein translation	Yes
GO:0000166	nucleotide binding	Yes
GO:0004812	aminoacyl-tRNA ligase activity	Yes
GO:0043436	oxoacid metabolic process	No
GO:0017076	purine nucleotide binding	No
GO:0006139	nucleobase-containing compound metabolic process	No
GO:0009987	cellular process	No
GO:0043170	macromolecule metabolic process	No
GO:0034641	cellular nitrogen compound metabolic process	No
GO:0043168	anion binding	No
GO:0140101	catalytic activity, acting on a tRNA	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0044238	primary metabolic process	No
GO:0003824	catalytic activity	No
GO:1901360	organic cyclic compound metabolic process	No
GO:0032553	ribonucleotide binding	No
GO:0071704	organic substance metabolic process	No
GO:0052689	carboxylic ester hydrolase activity	No
GO:0043038	amino acid activation	No
GO:0006399	tRNA metabolic process	No
GO:0019752	carboxylic acid metabolic process	No
GO:0097159	organic cyclic compound binding	No
GO:0032555	purine ribonucleotide binding	No
GO:1901363	heterocyclic compound binding	No
GO:0090304	nucleic acid metabolic process	No
GO:0046483	heterocycle metabolic process	No
GO:1901564	organonitrogen compound metabolic process	No
GO:0003674	molecular_function	No
GO:0036094	small molecule binding	No
GO:0044237	cellular metabolic process	No
GO:0034660	ncRNA metabolic process	No
GO:0016070	RNA metabolic process	No
GO:0005488	binding	No
GO:0043039	tRNA aminoacylation	No
GO:0016788	hydrolase activity, acting on ester bonds	No
GO:0006725	cellular aromatic compound metabolic process	No
GO:0016875	ligase activity, forming carbon-oxygen bonds	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0043167	ion binding	No
GO:0006807	nitrogen compound metabolic process	No
GO:1901265	nucleoside phosphate binding	No
GO:0008144	drug binding	No
GO:0008150	biological_process	No
GO:0016787	hydrolase activity	No
GO:0140098	catalytic activity, acting on RNA	No
GO:0016874	ligase activity	No
GO:0044281	small molecule metabolic process	No
GO:0008152	metabolic process	No
GO:0006082	organic acid metabolic process	No
GO:0006520	cellular amino acid metabolic process	No
GO:0030554	adenyl nucleotide binding	No
GO:0097367	carbohydrate derivative binding	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 61	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g8503.t1 MAQNSASQTPTGEPTAPTPQVDEQTRAEFADVAAKAPQNPQGGPAGAPKVKTEKELEKERKKAEKNKKFEERQAA KAKAAASKAAAPKVEKKVKPEKDKTADAYDPISIEAGRLEWWEERDLFKPEFGPDGKVKPEGSFVIPIPPPNVTG SLHMGHALTNALQDTMIRWQRMKGKTTLWLPGMDHAGISTQSVVEKMLWKKEKKTRHDIGREAMVNLIWDWKDEY HKNIKNALRRLGGSFDWSREAFTMDPNLSAAVTETFVRLHEEGIIYRANRLVNWCVALNTSLSNLEVENKEIEGR TLLDVPGYDKKVEFGVLTHFCYEVDGTTERIEIATTRPETMVGDTGIAVHPDDKRYQHLIGKNARHPFLDRLIPI FADTDVDPEFGTGAVKITPAHDFNDFNRGKAHNLEFISVMNDDGTFNKNAGPFAGMKRFDARYKVIEDLKEKGLY VKWEHNPMKVPRCAKSNDVIEPIMKPQWWMKMESLVQPAIDAVENGDIVIRPESAEKSYFRWMRNLNDWCLSRQL WWGHQAPAYFVKIEGEDGDDSDGNLWVTGRTEEDACKKAEEKFPGKKFSLVRDPDVLDTWFSSGLWPFSTLGWPR QTHDFENLYPTSVLETGWDILFFWVARMIMLGIKMTGQVPFREVYCHSLIRDSDGRKMSKSLGNVIDPLDVMEGI QLQTLHDKLQLGNIADKEIAAATRYQKKAFPKGIPECGADALRFALVSYTTGGGDIAFDIQVIHGYRKFCNKIYQ ATKFVLGKLGDDFKPQAGVKKTGHESLSERWILHKFNIAAKEMNEVLEQRDFSNSAQISYQYWYSQLCDVFIENS KYLLADDASAETKESAKQTLYTALEGGLTLIHPIMPFVTEHLWQRLPRREGDKTISIMKAKYPEYIAEFDDPAAA DAYELILNTSKAIRSILSQYDVKTQGDIIIQTYNTTSEKTVSGEMTTIKSLGGKTLGELSHLGPENKNPPSGCVV AAVGSDAAVYLRVSKEVALEQEEKAKASLAKARETVRRSQGIINGAGWKEKVKAEVREQEEKRLRDAEGEAARLE EQVKEFEKLRLE*
Coding	>Pro_DTO377G3_2|g8503.t1 ATGGCTCAAAACTCTGCCTCCCAAACCCCCACGGGTGAGCCTACGGCTCCAACCCCTCAGGTCGACGAACAGACT CGCGCCGAGTTCGCCGATGTTGCCGCAAAGGCCCCCCAGAATCCGCAGGGCGGACCGGCCGGCGCTCCCAAGGTG AAGACCGAGAAAGAGTTGGAAAAGGAACGCAAGAAGGCCGAAAAGAACAAGAAGTTCGAAGAGAGGCAGGCGGCC AAGGCCAAGGCTGCCGCCAGCAAGGCCGCAGCTCCTAAAGTCGAGAAGAAGGTGAAACCCGAGAAGGACAAGACC GCCGATGCCTACGATCCCATTTCCATCGAAGCCGGTCGTCTCGAATGGTGGGAGGAGCGTGATCTCTTCAAGCCC GAATTCGGACCTGATGGCAAGGTTAAGCCGGAAGGCTCCTTCGTCATCCCCATTCCCCCTCCCAATGTTACCGGT TCTCTTCACATGGGCCATGCCCTTACCAACGCCCTCCAGGACACCATGATCCGGTGGCAAAGAATGAAGGGCAAG ACTACCCTGTGGCTTCCCGGAATGGACCACGCCGGTATCTCGACTCAGAGCGTCGTCGAGAAGATGTTGTGGAAA AAGGAAAAGAAGACCCGTCACGATATTGGCCGAGAGGCCATGGTCAACTTGATCTGGGATTGGAAAGATGAATAC CACAAGAACATCAAGAACGCCCTGCGCAGACTTGGTGGTTCGTTCGACTGGAGCCGTGAGGCCTTCACCATGGAC CCCAACCTGTCAGCTGCTGTGACCGAGACCTTCGTTCGCCTCCACGAGGAGGGTATTATCTACCGTGCCAACCGC CTGGTCAACTGGTGTGTGGCTCTGAACACCTCTTTGTCTAACCTTGAGGTTGAGAACAAGGAAATCGAGGGCCGC ACACTTCTCGATGTGCCTGGCTACGACAAGAAGGTCGAATTCGGTGTTCTGACTCACTTCTGCTACGAGGTTGAT GGAACTACCGAGCGTATCGAGATTGCTACTACTCGTCCTGAGACCATGGTTGGTGATACCGGTATTGCCGTCCAC CCCGACGACAAGCGCTACCAGCATTTGATCGGCAAAAACGCTCGCCATCCTTTCTTGGACCGTCTGATCCCTATC TTTGCTGACACCGATGTCGACCCCGAATTCGGTACTGGTGCCGTCAAGATCACCCCCGCCCACGACTTTAACGAT TTCAACCGTGGTAAGGCCCACAACCTGGAGTTCATCTCTGTCATGAACGACGATGGTACCTTCAACAAGAATGCT GGTCCCTTTGCCGGCATGAAGCGCTTTGATGCCCGTTACAAGGTCATCGAAGACCTTAAGGAGAAGGGTCTGTAC GTCAAGTGGGAGCACAATCCCATGAAAGTGCCTCGTTGCGCCAAGTCCAACGATGTTATTGAGCCTATCATGAAG CCGCAATGGTGGATGAAGATGGAAAGCCTGGTTCAGCCTGCCATTGATGCCGTTGAGAATGGCGATATCGTTATC CGCCCCGAGTCCGCTGAGAAGAGCTACTTCCGCTGGATGCGAAACCTCAACGATTGGTGTCTGTCCCGTCAGCTC TGGTGGGGACACCAGGCTCCTGCTTACTTCGTCAAGATTGAAGGCGAGGATGGCGATGACAGTGACGGTAACCTC TGGGTCACTGGCCGTACCGAGGAGGATGCTTGCAAAAAGGCCGAGGAGAAGTTCCCCGGCAAGAAGTTTTCTCTG GTCCGTGATCCCGATGTTCTCGACACTTGGTTCTCTTCTGGCTTGTGGCCCTTCTCTACTCTGGGCTGGCCCCGC CAGACTCACGACTTCGAGAACCTATACCCCACCTCCGTTCTGGAGACTGGTTGGGATATTCTCTTCTTCTGGGTT GCCCGTATGATCATGCTGGGTATTAAGATGACTGGTCAGGTTCCTTTCCGTGAGGTTTACTGCCACTCTCTCATC AGAGATTCCGATGGCCGCAAGATGTCCAAGTCTCTGGGCAACGTTATCGATCCTCTGGATGTTATGGAGGGTATT CAGCTGCAGACTCTTCACGACAAGCTGCAGTTGGGCAACATTGCCGATAAGGAGATTGCTGCTGCTACCAGATAC CAGAAGAAGGCATTCCCCAAGGGTATCCCCGAGTGTGGCGCCGATGCTCTCCGCTTCGCCCTTGTCTCTTACACC ACCGGTGGAGGTGATATTGCTTTCGATATCCAGGTCATTCACGGCTACCGTAAGTTCTGTAACAAGATCTACCAG GCTACCAAGTTCGTCCTCGGCAAGCTTGGCGATGACTTCAAGCCCCAGGCTGGTGTTAAGAAGACTGGCCATGAA TCCCTTTCCGAGCGCTGGATTCTGCACAAGTTCAACATCGCCGCCAAGGAGATGAACGAGGTCCTTGAGCAGCGT GATTTCTCCAACTCCGCTCAGATCTCCTATCAGTACTGGTACTCCCAGCTGTGTGATGTGTTCATCGAGAACTCT AAGTACTTGCTGGCGGATGATGCCTCGGCTGAAACCAAGGAGTCTGCCAAGCAGACCCTCTACACGGCCCTTGAG GGTGGCCTGACCTTGATACACCCCATCATGCCGTTCGTCACCGAGCACCTGTGGCAGCGTCTACCCCGCCGCGAA GGTGATAAGACCATCTCGATCATGAAGGCCAAGTATCCCGAGTACATCGCCGAATTCGACGATCCGGCCGCCGCC GATGCCTACGAGCTCATTCTCAACACCTCCAAGGCCATCCGCTCGATCCTGTCTCAGTACGACGTCAAGACCCAG GGTGATATTATCATCCAGACCTACAACACTACCAGCGAAAAGACCGTGTCTGGGGAGATGACCACCATCAAGTCT CTGGGTGGTAAGACCCTCGGCGAGCTGTCTCACCTTGGCCCGGAGAACAAGAACCCTCCCTCTGGCTGCGTGGTG GCTGCTGTCGGCTCTGATGCCGCTGTCTACCTCCGTGTCTCCAAGGAGGTTGCGCTAGAGCAGGAAGAGAAGGCT AAGGCTAGCCTGGCCAAGGCCCGTGAGACTGTTCGCAGGTCTCAGGGTATTATCAACGGCGCTGGCTGGAAGGAG AAGGTCAAGGCCGAGGTCCGTGAGCAGGAGGAGAAGCGTCTGCGTGATGCTGAGGGCGAGGCTGCCCGTCTCGAG GAGCAGGTTAAGGAGTTTGAGAAGTTGCGTCTGGAGTAA
Transcript	>Pro_DTO377G3_2|g8503.t1 ATGGCTCAAAACTCTGCCTCCCAAACCCCCACGGGTGAGCCTACGGCTCCAACCCCTCAGGTCGACGAACAGACT CGCGCCGAGTTCGCCGATGTTGCCGCAAAGGCCCCCCAGAATCCGCAGGGCGGACCGGCCGGCGCTCCCAAGGTG AAGACCGAGAAAGAGTTGGAAAAGGAACGCAAGAAGGCCGAAAAGAACAAGAAGTTCGAAGAGAGGCAGGCGGCC AAGGCCAAGGCTGCCGCCAGCAAGGCCGCAGCTCCTAAAGTCGAGAAGAAGGTGAAACCCGAGAAGGACAAGACC GCCGATGCCTACGATCCCATTTCCATCGAAGCCGGTCGTCTCGAATGGTGGGAGGAGCGTGATCTCTTCAAGCCC GAATTCGGACCTGATGGCAAGGTTAAGCCGGAAGGCTCCTTCGTCATCCCCATTCCCCCTCCCAATGTTACCGGT TCTCTTCACATGGGCCATGCCCTTACCAACGCCCTCCAGGACACCATGATCCGGTGGCAAAGAATGAAGGGCAAG ACTACCCTGTGGCTTCCCGGAATGGACCACGCCGGTATCTCGACTCAGAGCGTCGTCGAGAAGATGTTGTGGAAA AAGGAAAAGAAGACCCGTCACGATATTGGCCGAGAGGCCATGGTCAACTTGATCTGGGATTGGAAAGATGAATAC CACAAGAACATCAAGAACGCCCTGCGCAGACTTGGTGGTTCGTTCGACTGGAGCCGTGAGGCCTTCACCATGGAC CCCAACCTGTCAGCTGCTGTGACCGAGACCTTCGTTCGCCTCCACGAGGAGGGTATTATCTACCGTGCCAACCGC CTGGTCAACTGGTGTGTGGCTCTGAACACCTCTTTGTCTAACCTTGAGGTTGAGAACAAGGAAATCGAGGGCCGC ACACTTCTCGATGTGCCTGGCTACGACAAGAAGGTCGAATTCGGTGTTCTGACTCACTTCTGCTACGAGGTTGAT GGAACTACCGAGCGTATCGAGATTGCTACTACTCGTCCTGAGACCATGGTTGGTGATACCGGTATTGCCGTCCAC CCCGACGACAAGCGCTACCAGCATTTGATCGGCAAAAACGCTCGCCATCCTTTCTTGGACCGTCTGATCCCTATC TTTGCTGACACCGATGTCGACCCCGAATTCGGTACTGGTGCCGTCAAGATCACCCCCGCCCACGACTTTAACGAT TTCAACCGTGGTAAGGCCCACAACCTGGAGTTCATCTCTGTCATGAACGACGATGGTACCTTCAACAAGAATGCT GGTCCCTTTGCCGGCATGAAGCGCTTTGATGCCCGTTACAAGGTCATCGAAGACCTTAAGGAGAAGGGTCTGTAC GTCAAGTGGGAGCACAATCCCATGAAAGTGCCTCGTTGCGCCAAGTCCAACGATGTTATTGAGCCTATCATGAAG CCGCAATGGTGGATGAAGATGGAAAGCCTGGTTCAGCCTGCCATTGATGCCGTTGAGAATGGCGATATCGTTATC CGCCCCGAGTCCGCTGAGAAGAGCTACTTCCGCTGGATGCGAAACCTCAACGATTGGTGTCTGTCCCGTCAGCTC TGGTGGGGACACCAGGCTCCTGCTTACTTCGTCAAGATTGAAGGCGAGGATGGCGATGACAGTGACGGTAACCTC TGGGTCACTGGCCGTACCGAGGAGGATGCTTGCAAAAAGGCCGAGGAGAAGTTCCCCGGCAAGAAGTTTTCTCTG GTCCGTGATCCCGATGTTCTCGACACTTGGTTCTCTTCTGGCTTGTGGCCCTTCTCTACTCTGGGCTGGCCCCGC CAGACTCACGACTTCGAGAACCTATACCCCACCTCCGTTCTGGAGACTGGTTGGGATATTCTCTTCTTCTGGGTT GCCCGTATGATCATGCTGGGTATTAAGATGACTGGTCAGGTTCCTTTCCGTGAGGTTTACTGCCACTCTCTCATC AGAGATTCCGATGGCCGCAAGATGTCCAAGTCTCTGGGCAACGTTATCGATCCTCTGGATGTTATGGAGGGTATT CAGCTGCAGACTCTTCACGACAAGCTGCAGTTGGGCAACATTGCCGATAAGGAGATTGCTGCTGCTACCAGATAC CAGAAGAAGGCATTCCCCAAGGGTATCCCCGAGTGTGGCGCCGATGCTCTCCGCTTCGCCCTTGTCTCTTACACC ACCGGTGGAGGTGATATTGCTTTCGATATCCAGGTCATTCACGGCTACCGTAAGTTCTGTAACAAGATCTACCAG GCTACCAAGTTCGTCCTCGGCAAGCTTGGCGATGACTTCAAGCCCCAGGCTGGTGTTAAGAAGACTGGCCATGAA TCCCTTTCCGAGCGCTGGATTCTGCACAAGTTCAACATCGCCGCCAAGGAGATGAACGAGGTCCTTGAGCAGCGT GATTTCTCCAACTCCGCTCAGATCTCCTATCAGTACTGGTACTCCCAGCTGTGTGATGTGTTCATCGAGAACTCT AAGTACTTGCTGGCGGATGATGCCTCGGCTGAAACCAAGGAGTCTGCCAAGCAGACCCTCTACACGGCCCTTGAG GGTGGCCTGACCTTGATACACCCCATCATGCCGTTCGTCACCGAGCACCTGTGGCAGCGTCTACCCCGCCGCGAA GGTGATAAGACCATCTCGATCATGAAGGCCAAGTATCCCGAGTACATCGCCGAATTCGACGATCCGGCCGCCGCC GATGCCTACGAGCTCATTCTCAACACCTCCAAGGCCATCCGCTCGATCCTGTCTCAGTACGACGTCAAGACCCAG GGTGATATTATCATCCAGACCTACAACACTACCAGCGAAAAGACCGTGTCTGGGGAGATGACCACCATCAAGTCT CTGGGTGGTAAGACCCTCGGCGAGCTGTCTCACCTTGGCCCGGAGAACAAGAACCCTCCCTCTGGCTGCGTGGTG GCTGCTGTCGGCTCTGATGCCGCTGTCTACCTCCGTGTCTCCAAGGAGGTTGCGCTAGAGCAGGAAGAGAAGGCT AAGGCTAGCCTGGCCAAGGCCCGTGAGACTGTTCGCAGGTCTCAGGGTATTATCAACGGCGCTGGCTGGAAGGAG AAGGTCAAGGCCGAGGTCCGTGAGCAGGAGGAGAAGCGTCTGCGTGATGCTGAGGGCGAGGCTGCCCGTCTCGAG GAGCAGGTTAAGGAGTTTGAGAAGTTGCGTCTGGAGTAA
Gene	>Pro_DTO377G3_2|g8503.t1 ATGGCTCAAAACTCTGCCTCCCAAACCCCCAGTGAGTTTCATGACTCATTCTCAGATGTCGCAGAAGCTTATAGT GAATAGCGGGTGAGCCTACGGCTCCAACCCCTCAGGTCGACGAACAGACTCGCGCCGAGTTCGCCGATGTTGCCG CAAAGGCCCCCCAGAATCCGCAGGGCGGACCGGCCGGCGCTCCCAAGGTGAAGACCGAGAAAGAGTGTATGTTAC CACCAAGATCTATATTCGGACCTTTCCTCGGAAGTCGTTTTTGTATAATGAGTATTTGCTGATACTGTGGGTGAT TCCTAGTGGAAAAGGAACGCAAGAAGGCCGAAAAGAACAAGAAGTTCGAAGAGAGGCAGGCGGCCAAGGCCAAGG CTGCCGCCAGCAAGGCCGCAGCTCCTAAAGTCGAGAAGAAGGTGAAACCCGAGAAGGACAAGACCGCCGATGCCT ACGATCCCATTTCCATCGAAGCCGGTCGTCTCGAATGGTGGGAGGAGCGTGATCTCTTCAAGCCCGAATTCGGAC CTGATGGCAAGGTTAAGCCGGAAGGCTCCTTCGTCATCCCCATTCCCCCTCCCAATGTTACCGGTTCTCTTCACA TGGGCCATGCCCTTACCAACGCCCTCCAGGACACCATGATCCGGTGGCAAAGAATGAAGGGCAAGACTACCCTGT GGCTTCCCGGAATGGACCACGCCGGTATCTCGACTCAGAGCGTCGTCGAGAAGATGTTGTGGAAAAAGGAAAAGA AGACCCGTCACGATATTGGCCGAGAGGCCATGGTCAACTTGATCTGGGATTGGAAAGATGAATACCACAAGAACA TCAAGAACGCCCTGCGCAGACTTGGTGGTTCGTTCGACTGGAGCCGTGAGGCCTTCACCATGGACCCCAACCTGT CAGCTGCTGTGACCGAGACCTTCGTTCGCCTCCACGAGGAGGGTATTATCTACCGTGCCAACCGCCTGGTCAACT GGTGTGTGGCTCTGAACACCTCTTTGTCTAACCTTGAGGTTGAGAACAAGGAAATCGAGGGCCGCACACTTCTCG ATGTGCCTGGCTACGACAAGAAGGTCGAATTCGGTGTTCTGACTCACTTCTGCTACGAGGTTGATGGAACTACCG AGCGTATCGAGATTGCTACTACTCGTCCTGAGACCATGGTTGGTGATACCGGTATTGCCGTCCACCCCGACGACA AGCGCTACCAGCATTTGATCGGCAAAAACGCTCGCCATCCTTTCTTGGACCGTCTGATCCCTATCTTTGCTGACA CCGATGTCGACCCCGAATTCGGTACTGGTGCCGTCAAGATCACCCCCGCCCACGACTTTAACGATTTCAACCGTG GTAAGGCCCACAACCTGGAGTTCATCTCTGTCATGAACGACGATGGTACCTTCAACAAGAATGCTGGTCCCTTTG CCGGCATGAAGCGCTTTGATGCCCGTTACAAGGTCATCGAAGACCTTAAGGAGAAGGGTCTGTACGTCAAGTGGG AGCACAATCCCATGAAAGTGCCTCGTTGCGCCAAGTCCAACGATGTTATTGAGCCTATCATGAAGCCGCAATGGT GGATGAAGATGGAAAGCCTGGTTCAGCCTGCCATTGATGCCGTTGAGAATGGCGATATCGTTATCCGCCCCGAGT CCGCTGAGAAGAGCTACTTCCGCTGGATGCGAAACCTCAACGATTGGTGTCTGTCCCGTCAGCTCTGGTGGGGAC ACCAGGCTCCTGCTTACTTCGTCAAGATTGAAGGCGAGGATGGCGATGACAGTGACGGTAACCTCTGGGTCACTG GCCGTACCGAGGAGGATGCTTGCAAAAAGGCCGAGGAGAAGTTCCCCGGCAAGAAGTTTTCTCTGGTCCGTGATC CCGATGTTCTCGACACTTGGTTCTCTTCTGGCTTGTGGCCCTTCTCTACTCTGGGCTGGCCCCGCCAGACTCACG ACTTCGAGAACCTATACCCCACCTCCGTTCTGGAGACTGGTTGGGATATTCTCTTCTTCTGGGTTGCCCGTATGA TCATGCTGGGTATTAAGATGACTGGTCAGGTTCCTTTCCGTGAGGTTTACTGCCACTCTCTCATCAGAGATTCCG ATGGCCGCAAGATGTCCAAGTCTCTGGGCAACGTTATCGATCCTCTGGATGTTATGGAGGGTATTCAGCTGCAGA CTCTTCACGACAAGCTGCAGTTGGGCAACATTGCCGATAAGGAGATTGCTGCTGCTACCAGATACCAGAAGAAGG CATTCCCCAAGGGTATCCCCGAGTGTGGCGCCGATGCTCTCCGCTTCGCCCTTGTCTCTTACACCACCGGTGGTA GGTTTCATCTCATGTCCTTGTTTGATTCCATTTACTAATCATGATTTGCAGGAGGTGATATTGCTTTCGATATCC AGGTCATTCACGGCTACCGTAAGTTCTGTAACAAGATCTACCAGGCTACCAAGTTCGTCCTCGGCAAGCTTGGCG ATGACTTCAAGCCCCAGGCTGGTGTTAAGAAGACTGGCCATGAATCCCTTTCCGAGCGCTGGATTCTGCACAAGT TCAACATCGCCGCCAAGGAGATGAACGAGGTCCTTGAGCAGCGTGATTTCTCCAACTCCGCTCAGATCTCCTATC AGTACTGGTACTCCCAGCTGTGTGATGTGTTCATCGAGAACTCTAAGTACTTGCTGGCGGATGATGCCTCGGCTG AAACCAAGGAGTCTGCCAAGCAGACCCTCTACACGGCCCTTGAGGGTGGCCTGACCTTGATACACCCCATCATGC CGTTCGTCACCGAGCACCTGTGGCAGCGTCTACCCCGCCGCGAAGGTGATAAGACCATCTCGATCATGAAGGCCA AGTATCCCGAGTACATCGCCGAATTCGACGATCCGGCCGCCGCCGATGCCTACGAGCTCATTCTCAACACCTCCA AGGCCATCCGCTCGATCCTGTCTCAGTACGACGTCAAGACCCAGGGTGATATTATCATCCAGACCTACAACACTA CCAGCGAAAAGACCGTGTCTGGGGAGATGACCACCATCAAGTCTCTGGGTGGTAAGACCCTCGGCGAGCTGTCTC ACCTTGGCCCGGAGAACAAGAACCCTCCCTCTGGCTGCGTGGTGGCTGCTGTCGGCTCTGATGCCGCTGTCTACC TCCGTGTCTCCAAGGAGGTTGCGCTAGAGCAGGAAGAGAAGGCTAAGGCTAGCCTGGCCAAGGCCCGTGAGACTG TTCGCAGGTCTCAGGGTATTATCAACGGCGCTGGCTGGAAGGAGAAGGTCAAGGCCGAGGTCCGTGAGCAGGAGG AGAAGCGTCTGCGTGATGCTGAGGGCGAGGCTGCCCGTCTCGAGGAGCAGGTTAAGGAGTTTGAGAAGTTGCGTC TGGAGTAA