Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g7531.t1
Gene name
Location	scaffold_24:57275..61309
Strand	-
Gene length (bp)	4034
Transcript length (bp)	3597
Coding sequence length (bp)	3597
Protein length (aa)	1199

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00732	GMC_oxred_N	GMC oxidoreductase	7.3E-11	106	327
PF05199	GMC_oxred_C	GMC oxidoreductase	3.6E-08	501	573
PF00890	FAD_binding_2	FAD binding domain	1.2E-04	26	63

GO

GO Term	Description	Terminal node
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	Yes
GO:0050660	flavin adenine dinucleotide binding	Yes
GO:1901265	nucleoside phosphate binding	No
GO:0016491	oxidoreductase activity	No
GO:0097159	organic cyclic compound binding	No
GO:0005488	binding	No
GO:0043167	ion binding	No
GO:0000166	nucleotide binding	No
GO:0043168	anion binding	No
GO:1901363	heterocyclic compound binding	No
GO:0003674	molecular_function	No
GO:0003824	catalytic activity	No
GO:0036094	small molecule binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 40	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	789	811	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g7531.t1 MSNFTDRTDKYPNLSRPFRSMRPEYDVVVIGSGYGAGVAASRMARAGKSVAVLELGWERRSGSFPQTFSQCLKNT SISGSSVKGSFISKWLSPGDPTRLFQVFLGDGQHSFAAHGLGGSSLINAGVFLKADRRTLQMSPWPSEIRDQPSA LDEHYARAETMLQPSTYPDDLSPNKLKHLQEELRWLGKRNNFYRVPLTIFFHNGCNNAGVPMQANRQSGHECTGL NDGSKNSVATTYLADAWNWGAEIFCGCEVRFVENMDGGGYTIHFAWHGSGRSVFADHFKEQLFWVKAKEFCFLGA GALGTTEVLLRSKQHGLHMSPLVGRNLSGNGDFLIFGYNGYANINGIAGESSRAPPGTTVTAVIDNRVVDPLDNP LSGYVIQDGCIPAMFNPVIQIMLTLQTMKSQALCCLWNPRQEAKKTLASLKSLLFGPYAYNGALQRTSTYLVMSH DSNEITLILKDDRLYLRGPGEGRSEHFKWIKNLFNESFARTGSRMGFSYFYGRHQEETTVHLLGGANMSNDGTGH GGVTNHLGEVFSGSNGEVYKGLVCCDASIIPTALGVNPLGTISALSERSVSLITERSGLSIDIETENQTLNAYCK PSISCDFQDHQDSTEKTSQSIGWKFTETMHGHISMRSDNGSFALSERVGKGSSCAMRMFLTIEICRDSQYQGICT GTISCYALSRATLKIVEGTVDFFTPIEENAESSAISYHLKLLSVEGIEYRLKGHKLINTNIAFSARKTWEATTTV NVNITRLDGTTIGAGALHISLLDFQKQMRTFRTTKDFQISLILALVWFLVSFIYHISLFFVRPFVRMRFPQISTK GTDVKQPPSTSCNVTASDGVQIHLDIYDPLPAQKTDEPGPNCNLAPVLLLPGVTGIGAMHNLYSLPFLRCNMVEY LTQRGHRCYALTPRWGCDPAVAQKSTVFDCRLDVAAAIAYIRDKERQKPYVVAHCQGSVALCMGLLDGTIQSSQL LGVTANSVFMNQVFGYWNSLKGRTTLLIQFYELLAGNYFPIVSSAKSVLLQRLLDTLLRLYPVGHTRDICTSTAC HRTSFAFGLLWNHENLDMSLHDNVHQFFAGTHTKLMKHVVRMGTRGICMDNDSCPLLTDENLQRLQGLPILFVSG TENQVFSPESTLKDYELLRRRFGERLYRRFLVEGYGHLDPIVGKDAAEDVYWRIFAHLRWCTKEAESTNLRAK*
Coding	>Pro_DTO377G3_2|g7531.t1 ATGTCAAATTTCACAGACAGGACGGACAAGTACCCGAACCTGAGTCGTCCGTTCAGATCAATGAGGCCGGAATAT GATGTCGTGGTAATAGGATCTGGCTATGGTGCTGGAGTAGCGGCAAGTCGAATGGCCCGAGCAGGGAAGAGCGTC GCAGTGCTAGAGCTTGGCTGGGAAAGAAGATCCGGTTCATTTCCACAAACGTTCTCTCAATGTCTGAAGAACACG AGCATCTCGGGGAGTTCTGTAAAGGGCTCCTTCATTTCAAAGTGGCTGTCGCCTGGAGACCCCACGCGGCTTTTC CAAGTATTCTTAGGCGATGGACAGCATTCGTTTGCTGCTCATGGACTTGGAGGATCTTCATTGATCAATGCCGGG GTTTTCCTGAAAGCGGATAGGAGAACATTGCAGATGAGTCCATGGCCGTCAGAGATCAGGGACCAGCCATCTGCG CTCGACGAACACTACGCACGCGCCGAAACAATGCTACAGCCTTCCACATACCCGGATGATTTAAGCCCAAACAAA CTCAAGCATCTCCAAGAAGAGTTGAGATGGCTAGGAAAGAGGAATAATTTCTATCGAGTACCGTTGACTATATTT TTCCACAATGGCTGCAACAATGCAGGTGTCCCTATGCAGGCAAACAGACAATCAGGCCATGAGTGCACTGGTCTC AACGATGGGTCAAAGAACTCGGTGGCGACAACATATCTTGCAGATGCCTGGAATTGGGGAGCTGAGATATTCTGC GGATGCGAAGTTCGATTTGTAGAAAATATGGACGGAGGAGGCTACACTATACACTTTGCTTGGCATGGAAGTGGG AGGTCGGTGTTTGCGGATCATTTCAAGGAACAACTCTTTTGGGTCAAAGCAAAGGAGTTCTGTTTTCTTGGGGCT GGCGCTCTAGGAACTACTGAAGTCTTGCTTCGGTCAAAGCAGCACGGCCTCCATATGTCACCGCTTGTTGGAAGG AATCTCTCTGGAAATGGGGACTTTTTGATATTTGGTTACAACGGATATGCTAATATCAACGGGATCGCCGGTGAA TCCTCGCGTGCTCCCCCTGGAACAACAGTCACTGCTGTTATTGATAACCGAGTCGTTGATCCTCTGGACAATCCT CTTTCTGGATATGTTATCCAAGATGGTTGCATTCCTGCGATGTTCAACCCGGTAATCCAAATCATGCTCACCCTG CAAACTATGAAGAGCCAGGCGCTGTGTTGTCTTTGGAACCCTCGCCAAGAAGCTAAGAAGACCCTTGCCTCTCTC AAGTCTCTGCTATTCGGTCCGTATGCATACAATGGAGCTCTTCAGCGGACTTCAACTTATCTGGTGATGTCTCAT GACAGCAACGAGATAACTTTGATCTTGAAGGATGATCGATTGTACCTCCGGGGACCGGGAGAAGGGCGATCTGAG CATTTCAAATGGATAAAGAACCTTTTCAATGAGAGTTTTGCTCGCACAGGCTCAAGGATGGGGTTTTCCTATTTT TACGGTCGTCACCAGGAGGAAACCACAGTCCATCTCCTTGGAGGAGCCAACATGAGCAACGATGGAACAGGGCAT GGGGGTGTGACAAATCATCTAGGAGAGGTTTTCAGTGGCTCTAATGGTGAAGTATACAAAGGCCTCGTGTGCTGT GATGCATCTATCATCCCGACAGCCCTGGGCGTGAACCCACTCGGCACAATATCAGCCCTCTCCGAGCGATCCGTC AGTTTGATTACCGAGAGATCTGGATTATCAATTGATATTGAGACTGAAAATCAGACTTTAAACGCCTACTGCAAG CCTAGTATATCGTGCGATTTCCAAGACCATCAAGACAGTACCGAGAAAACATCGCAGTCGATAGGATGGAAATTC ACAGAGACTATGCATGGGCACATCAGCATGCGGTCGGATAACGGAAGTTTTGCGCTTTCTGAGAGGGTAGGAAAA GGCTCATCTTGCGCGATGCGGATGTTTCTTACGATCGAAATCTGCCGAGATTCACAATACCAAGGAATATGCACC GGGACGATTTCTTGTTACGCATTATCTAGAGCCACGCTCAAGATTGTCGAAGGAACGGTAGACTTTTTCACGCCA ATAGAGGAGAATGCCGAATCATCAGCTATATCATATCACCTGAAGCTGCTATCGGTAGAGGGCATAGAGTACCGC CTGAAAGGCCACAAGCTGATCAACACAAACATAGCCTTTTCCGCCAGAAAGACCTGGGAAGCGACAACTACGGTG AATGTCAATATCACTCGACTGGACGGGACAACTATTGGAGCAGGGGCCCTTCATATCTCATTGCTAGACTTCCAA AAGCAGATGCGGACATTTCGGACGACAAAAGACTTCCAGATCAGTCTTATCTTGGCCTTGGTGTGGTTTTTGGTT TCTTTTATTTACCACATCAGTTTGTTCTTCGTTCGCCCTTTCGTCCGCATGCGCTTCCCTCAGATCTCAACTAAA GGCACCGATGTAAAACAACCACCTTCTACCTCGTGCAATGTCACCGCAAGCGATGGCGTACAGATACATCTTGAT ATATATGACCCACTCCCCGCACAAAAGACAGACGAGCCAGGACCTAACTGCAATCTTGCACCAGTCCTACTTCTA CCCGGAGTCACTGGGATCGGCGCGATGCACAATTTGTATTCACTGCCATTTTTGCGCTGCAACATGGTTGAGTAT CTCACACAGCGTGGACACCGATGCTACGCACTCACCCCTCGCTGGGGCTGTGATCCCGCGGTTGCGCAGAAAAGC ACAGTCTTCGACTGCCGTCTTGACGTTGCTGCTGCAATAGCATATATTCGCGACAAAGAGCGACAGAAGCCCTAT GTGGTAGCCCATTGCCAAGGCTCGGTGGCTCTCTGCATGGGCCTGCTGGATGGAACCATCCAAAGTAGCCAACTT CTCGGCGTTACTGCCAACTCAGTCTTCATGAATCAGGTCTTTGGGTACTGGAACTCCCTCAAGGGGAGAACGACT CTGCTGATCCAGTTCTACGAATTACTGGCTGGGAATTACTTCCCGATTGTCAGCAGTGCTAAGAGTGTTCTTCTC CAACGATTACTCGATACGCTCCTTCGTCTCTATCCTGTTGGACACACGCGGGACATCTGCACATCTACAGCGTGT CACCGGACATCTTTTGCTTTTGGGCTACTATGGAATCACGAGAACCTTGATATGAGTCTGCATGACAATGTTCAC CAATTTTTCGCGGGGACACATACGAAGCTTATGAAACACGTGGTTCGCATGGGAACTCGGGGGATTTGCATGGAT AATGATTCATGTCCTCTTCTGACAGATGAGAATTTGCAGCGACTGCAAGGGTTGCCGATTCTCTTTGTCTCGGGT ACGGAGAACCAAGTTTTCAGTCCTGAGTCTACGCTCAAGGACTACGAGTTGCTGCGACGTCGATTCGGCGAGAGA CTGTATCGCAGGTTCCTAGTCGAGGGGTATGGGCATCTTGATCCTATTGTAGGAAAGGATGCGGCCGAGGATGTA TATTGGAGGATCTTTGCGCATTTGAGATGGTGCACCAAAGAGGCGGAAAGTACGAATTTGAGAGCCAAGTAA
Transcript	>Pro_DTO377G3_2|g7531.t1 ATGTCAAATTTCACAGACAGGACGGACAAGTACCCGAACCTGAGTCGTCCGTTCAGATCAATGAGGCCGGAATAT GATGTCGTGGTAATAGGATCTGGCTATGGTGCTGGAGTAGCGGCAAGTCGAATGGCCCGAGCAGGGAAGAGCGTC GCAGTGCTAGAGCTTGGCTGGGAAAGAAGATCCGGTTCATTTCCACAAACGTTCTCTCAATGTCTGAAGAACACG AGCATCTCGGGGAGTTCTGTAAAGGGCTCCTTCATTTCAAAGTGGCTGTCGCCTGGAGACCCCACGCGGCTTTTC CAAGTATTCTTAGGCGATGGACAGCATTCGTTTGCTGCTCATGGACTTGGAGGATCTTCATTGATCAATGCCGGG GTTTTCCTGAAAGCGGATAGGAGAACATTGCAGATGAGTCCATGGCCGTCAGAGATCAGGGACCAGCCATCTGCG CTCGACGAACACTACGCACGCGCCGAAACAATGCTACAGCCTTCCACATACCCGGATGATTTAAGCCCAAACAAA CTCAAGCATCTCCAAGAAGAGTTGAGATGGCTAGGAAAGAGGAATAATTTCTATCGAGTACCGTTGACTATATTT TTCCACAATGGCTGCAACAATGCAGGTGTCCCTATGCAGGCAAACAGACAATCAGGCCATGAGTGCACTGGTCTC AACGATGGGTCAAAGAACTCGGTGGCGACAACATATCTTGCAGATGCCTGGAATTGGGGAGCTGAGATATTCTGC GGATGCGAAGTTCGATTTGTAGAAAATATGGACGGAGGAGGCTACACTATACACTTTGCTTGGCATGGAAGTGGG AGGTCGGTGTTTGCGGATCATTTCAAGGAACAACTCTTTTGGGTCAAAGCAAAGGAGTTCTGTTTTCTTGGGGCT GGCGCTCTAGGAACTACTGAAGTCTTGCTTCGGTCAAAGCAGCACGGCCTCCATATGTCACCGCTTGTTGGAAGG AATCTCTCTGGAAATGGGGACTTTTTGATATTTGGTTACAACGGATATGCTAATATCAACGGGATCGCCGGTGAA TCCTCGCGTGCTCCCCCTGGAACAACAGTCACTGCTGTTATTGATAACCGAGTCGTTGATCCTCTGGACAATCCT CTTTCTGGATATGTTATCCAAGATGGTTGCATTCCTGCGATGTTCAACCCGGTAATCCAAATCATGCTCACCCTG CAAACTATGAAGAGCCAGGCGCTGTGTTGTCTTTGGAACCCTCGCCAAGAAGCTAAGAAGACCCTTGCCTCTCTC AAGTCTCTGCTATTCGGTCCGTATGCATACAATGGAGCTCTTCAGCGGACTTCAACTTATCTGGTGATGTCTCAT GACAGCAACGAGATAACTTTGATCTTGAAGGATGATCGATTGTACCTCCGGGGACCGGGAGAAGGGCGATCTGAG CATTTCAAATGGATAAAGAACCTTTTCAATGAGAGTTTTGCTCGCACAGGCTCAAGGATGGGGTTTTCCTATTTT TACGGTCGTCACCAGGAGGAAACCACAGTCCATCTCCTTGGAGGAGCCAACATGAGCAACGATGGAACAGGGCAT GGGGGTGTGACAAATCATCTAGGAGAGGTTTTCAGTGGCTCTAATGGTGAAGTATACAAAGGCCTCGTGTGCTGT GATGCATCTATCATCCCGACAGCCCTGGGCGTGAACCCACTCGGCACAATATCAGCCCTCTCCGAGCGATCCGTC AGTTTGATTACCGAGAGATCTGGATTATCAATTGATATTGAGACTGAAAATCAGACTTTAAACGCCTACTGCAAG CCTAGTATATCGTGCGATTTCCAAGACCATCAAGACAGTACCGAGAAAACATCGCAGTCGATAGGATGGAAATTC ACAGAGACTATGCATGGGCACATCAGCATGCGGTCGGATAACGGAAGTTTTGCGCTTTCTGAGAGGGTAGGAAAA GGCTCATCTTGCGCGATGCGGATGTTTCTTACGATCGAAATCTGCCGAGATTCACAATACCAAGGAATATGCACC GGGACGATTTCTTGTTACGCATTATCTAGAGCCACGCTCAAGATTGTCGAAGGAACGGTAGACTTTTTCACGCCA ATAGAGGAGAATGCCGAATCATCAGCTATATCATATCACCTGAAGCTGCTATCGGTAGAGGGCATAGAGTACCGC CTGAAAGGCCACAAGCTGATCAACACAAACATAGCCTTTTCCGCCAGAAAGACCTGGGAAGCGACAACTACGGTG AATGTCAATATCACTCGACTGGACGGGACAACTATTGGAGCAGGGGCCCTTCATATCTCATTGCTAGACTTCCAA AAGCAGATGCGGACATTTCGGACGACAAAAGACTTCCAGATCAGTCTTATCTTGGCCTTGGTGTGGTTTTTGGTT TCTTTTATTTACCACATCAGTTTGTTCTTCGTTCGCCCTTTCGTCCGCATGCGCTTCCCTCAGATCTCAACTAAA GGCACCGATGTAAAACAACCACCTTCTACCTCGTGCAATGTCACCGCAAGCGATGGCGTACAGATACATCTTGAT ATATATGACCCACTCCCCGCACAAAAGACAGACGAGCCAGGACCTAACTGCAATCTTGCACCAGTCCTACTTCTA CCCGGAGTCACTGGGATCGGCGCGATGCACAATTTGTATTCACTGCCATTTTTGCGCTGCAACATGGTTGAGTAT CTCACACAGCGTGGACACCGATGCTACGCACTCACCCCTCGCTGGGGCTGTGATCCCGCGGTTGCGCAGAAAAGC ACAGTCTTCGACTGCCGTCTTGACGTTGCTGCTGCAATAGCATATATTCGCGACAAAGAGCGACAGAAGCCCTAT GTGGTAGCCCATTGCCAAGGCTCGGTGGCTCTCTGCATGGGCCTGCTGGATGGAACCATCCAAAGTAGCCAACTT CTCGGCGTTACTGCCAACTCAGTCTTCATGAATCAGGTCTTTGGGTACTGGAACTCCCTCAAGGGGAGAACGACT CTGCTGATCCAGTTCTACGAATTACTGGCTGGGAATTACTTCCCGATTGTCAGCAGTGCTAAGAGTGTTCTTCTC CAACGATTACTCGATACGCTCCTTCGTCTCTATCCTGTTGGACACACGCGGGACATCTGCACATCTACAGCGTGT CACCGGACATCTTTTGCTTTTGGGCTACTATGGAATCACGAGAACCTTGATATGAGTCTGCATGACAATGTTCAC CAATTTTTCGCGGGGACACATACGAAGCTTATGAAACACGTGGTTCGCATGGGAACTCGGGGGATTTGCATGGAT AATGATTCATGTCCTCTTCTGACAGATGAGAATTTGCAGCGACTGCAAGGGTTGCCGATTCTCTTTGTCTCGGGT ACGGAGAACCAAGTTTTCAGTCCTGAGTCTACGCTCAAGGACTACGAGTTGCTGCGACGTCGATTCGGCGAGAGA CTGTATCGCAGGTTCCTAGTCGAGGGGTATGGGCATCTTGATCCTATTGTAGGAAAGGATGCGGCCGAGGATGTA TATTGGAGGATCTTTGCGCATTTGAGATGGTGCACCAAAGAGGCGGAAAGTACGAATTTGAGAGCCAAGTAA
Gene	>Pro_DTO377G3_2|g7531.t1 ATGTCAAATTTCACAGACAGGACGGACAAGTACCCGAACCTGAGTCGTCCGTTCAGATCAATGAGGCCGGAATAT GATGTCGTGGTAATAGGATCTGGCTATGGTGCTGGAGTAGCGGCAAGTCGAATGGCCCGAGCAGGGAAGAGCGTC GCAGTGCTAGAGCTTGGCTGGGAAAGAAGATGTACGGATCGAGAGCGTCAAGCAAATACCATCGCTAACATTCCC ATAAGCCGGTTCATTTCCACAAACGTTCTCTCAATGTCTGAAGAACACGAGCATCTCGGGGAGTTCTGTAAAGGG CTCCTTCATTTCAAAGTGGCTGTCGCCTGGAGACCCCACGCGGCTTTTCCAAGTATTCTTAGGCGATGGACAGCA TTCGTTTGCTGCTCATGGTATGTGATACTCAACATCTCCCTAGAATTGATGATTAGGGAAACCTGACAGCCTTTT TCTATATTGCATAGGACTTGGAGGATCTTCATTGATCAATGCCGGGGTTTTCCTGAAAGCGGATAGGAGAACATT GCAGATGAGTCCATGGCCGTCAGAGATCAGGGACCAGCCATCTGCGCTCGACGAACGTGAGTTTTATATGCATGG TGGAGAACATTTCATAATAACCAATGCAGACTACGCACGCGCCGAAACAATGCTACAGCCTTCCACATACCCGGA TGATTTAAGCCCAAACAAACTCAAGCATCTCCAAGAAGAGTTGAGATGGCTAGGAAAGAGGAATAATTTCTATCG AGTACCGTTGACTATATTTTTCCACAATGGCTGCAACAATGCAGGTGTCCCTATGCAGGCAAACAGACAATCAGG CCATGAGTGCACTGGTCTCAACGATGGGTCAAAGAACTCGGTGGCGACAACATATCTTGCAGATGCCTGGAATTG GGGAGCTGAGATATTCTGCGGATGCGAAGTTCGATTTGTAGAAAATATGGACGGAGGAGGCTACACTATACACTT TGCTTGGCATGGAAGTGGGAGGTCGGTGTTTGCGGATCATTTCAAGGAACAACTCTTTTGGGTCAAAGCAGTAAG TATCGAATTCACTTCGGAAGTGGACATATCAACTCACTCTTTCTACTTCAATCACAGAAGGAGTTCTGTTTTCTT GGGGCTGGCGCTCTAGGAACTACTGAAGTCTTGCTTCGGTCAAAGCAGCACGGCCTCCATATGTCACCGCTTGTT GGAAGGAATCTCTCTGGAAATGGGGACTTTTTGATATTTGGTACGTACTTCCCCAGAATATCAGTCCGAGCACAT TTGATTTACAGATTCAAGGTTACAACGGATATGCTAATATCAACGGGATCGCCGGTGAATCCTCGCGTGCTCCCC CTGGAACAACAGTCACTGCTGTTATTGATAACCGAGTCGTTGATCCTCTGGACAATCCTCTTTCTGGATATGTTA TCCAAGATGGTTGCATTCCTGCGATGTTCAACCCGGTAATCCAAATCATGCTCACCCTGCAAACTATGAAGAGCC AGGCGCTGTGTTGTCTTTGGAACCCTCGCCAAGAAGCTAAGAAGACCCTTGCCTCTCTCAAGTCTCTGCTATTCG GTCCGTATGCATACAATGGAGCTCTTCAGCGGACTTCAACTTATCTGGTGATGTCTCATGACAGCAACGAGATAA CTTTGATCTTGAAGGATGATCGATTGTACCTCCGGGGACCGGGAGAAGGGCGATCTGAGCATTTCAAATGGATAA AGAACCTTTTCAATGAGAGTTTTGCTCGCACAGGCTCAAGGATGGGGTTTTCCTATTTTTACGGTAACAATCGAT AAAAGCCATAACAAAGCTGCGCTAAACATAGCCAAAGGTCGTCACCAGGAGGAAACCACAGTCCATCTCCTTGGA GGAGCCAACATGAGCAACGATGGAACAGGGCATGGGGGTGTGACAAATCATCTAGGAGAGGTTTTCAGTGGCTCT AATGGTGAAGTATACAAAGGCCTCGTGTGCTGTGATGCATCTATCATCCCGACAGCCCTGGGTATGTTGCAAGTA AAAATTTATGGCTTACTATGTGCTGATTCTGATAGGCGTGAACCCACTCGGCACAATATCAGCCCTCTCCGAGCG ATCCGTCAGTTTGATTACCGAGAGATCTGGATTATCAATTGATATTGAGACTGAAAATCAGACTTTAAACGCCTA CTGCAAGCCTAGTATATCGTGCGATTTCCAAGACCATCAAGACAGTACCGAGAAAACATCGCAGTCGATAGGATG GAAATTCACAGAGACTATGCATGGGCACATCAGCATGCGGTCGGATAACGGAAGTTTTGCGCTTTCTGAGAGGGT AGGAAAAGGCTCATCTTGCGCGATGCGGATGTTTCTTACGATCGAAATCTGCCGAGGTGAGAAACCGAGAGTCGA GAGAGCACTCTGGCAGTAGAATGCTCACATGTACAGATTCACAATACCAAGGAATATGCACCGGGACGATTTCTT GTTACGCATTATCTAGAGCCACGCTCAAGATTGTCGAAGGAACGGTAGACTTTTTCACGCCAATAGAGGAGAATG CCGAATCATCAGCTATATCATATCACCTGAAGCTGCTATCGGTAGAGGGCATAGAGTACCGCCTGAAAGGCCACA AGCTGATCAACACAAACATAGCCTTTTCCGCCAGAAAGACCTGGGAAGCGACAACTACGGTGAATGTCAATATCA CTCGACTGGACGGGACAACTATTGGAGCAGGGGCCCTTCATATCTCATTGCTAGACTTCCAAAAGCAGATGCGGA CATTTCGGACGACAAAAGACTTCCAGATCAGTCTTATCTTGGCCTTGGTGTGGTTTTTGGTTTCTTTTATTTACC ACATCAGTTTGTTCTTCGTTCGCCCTTTCGTCCGCATGCGCTTCCCTCAGATCTCAACTAAAGGCACCGATGTAA AACAACCACCTTCTACCTCGTGCAATGTCACCGCAAGCGATGGCGTACAGATACATCTTGATATATATGACCCAC TCCCCGCACAAAAGACAGACGAGCCAGGACCTAACTGCAATCTTGCACCAGTCCTACTTCTACCCGGAGTCACTG GGATCGGCGCGATGCACAATTTGTATTCACTGCCATTTTTGCGCTGCAACATGGTTGAGTATCTCACACAGCGTG GACACCGATGCTACGCACTCACCCCTCGCTGGGGCTGTGATCCCGCGGTTGCGCAGAAAAGCACAGTCTTCGACT GCCGTCTTGACGTTGCTGCTGCAATAGCATATATTCGCGACAAAGAGCGACAGAAGCCCTATGTGGTAGCCCATT GCCAAGGCTCGGTGGCTCTCTGCATGGGCCTGCTGGATGGAACCATCCAAAGTAGCCAACTTCTCGGCGTTACTG CCAACTCAGTCTTCATGAATCAGGTCTTTGGGTACTGGAACTCCCTCAAGGGGAGAACGACTCTGCTGATCCAGT TCTACGAATTACTGGCTGGGAATTACTTCCCGATTGTCAGCAGTGCTAAGAGTGTTCTTCTCCAACGATTACTCG ATACGCTCCTTCGTCTCTATCCTGTTGGACACACGCGGGACATCTGCACATCTACAGCGTGTCACCGGACATCTT TTGCTTTTGGGCTACTATGGAATCACGAGAACCTTGATATGAGTCTGCATGACAATGTTCACCAATTTTTCGCGG GGACACATACGAAGCTTATGAAACACGTGGTTCGCATGGGAACTCGGGGGATTTGCATGGATAATGATTCATGTC CTCTTCTGACAGATGAGAATTTGCAGCGACTGCAAGGGTTGCCGATTCTCTTTGTCTCGGGTACGGAGAACCAAG TTTTCAGTCCTGAGTCTACGCTCAAGGACTACGAGTTGCTGCGACGTCGATTCGGCGAGAGACTGTATCGCAGGT TCCTAGTCGAGGGGTATGGGCATCTTGATCCTATTGTAGGAAAGGATGCGGCCGAGGATGTATATTGGAGGATCT TTGCGCATTTGAGATGGTGCACCAAAGAGGCGGAAAGTACGAATTTGAGAGCCAAGTAA