Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g7520.t1
Gene name
Location	scaffold_24:28999..32569
Strand	+
Gene length (bp)	3570
Transcript length (bp)	3570
Coding sequence length (bp)	3570
Protein length (aa)	1190

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00403	HMA	Heavy-metal-associated domain	1.5E-10	20	80
PF00403	HMA	Heavy-metal-associated domain	4.9E-12	108	168
PF00403	HMA	Heavy-metal-associated domain	3.2E-11	199	260
PF00403	HMA	Heavy-metal-associated domain	1.4E-07	283	340
PF00122	E1-E2_ATPase	E1-E2 ATPase	9.9E-48	554	735
PF00702	Hydrolase	haloacid dehalogenase-like hydrolase	4.7E-37	753	1003

GO

GO Term	Description	Terminal node
GO:0046872	metal ion binding	Yes
GO:0005488	binding	No
GO:0043167	ion binding	No
GO:0043169	cation binding	No
GO:0003674	molecular_function	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 18	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	369	391	22
2	401	423	22
3	444	466	22
4	476	493	17
5	657	679	22
6	699	721	22
7	1049	1071	22
8	1081	1103	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g7520.t1 MLSTNPHAGGAGRPALATTTLKIDGMTCGACTSAVEGAFQGVDGAHDVSVSLIMGRATVQHDPSVLPPAKVAEMI EDRGFDATVLSTEEQRNPDSTSSSPAMRLSVTTLAIEGMTCGACTSAVESGLNDVSGVNSVDVSLLSERAVVEHD AGIITPEQIAELIEDRGFGARVLDTALVGSKEPPAPAGSEEKSGLLVTTIAIGGMTCGACTSSVQGALGSVDGVI QFNISLLAERAVVVHDPTILPASKIPELVEDAGFDASIVSSEAQASISKKTQQINLSLHGLRDGVSATALEDNIL QHSGVHSASIKMATSRMAISFDPSTIGIRSIVEIIEAAGYNALIVDSDDTNAQLQSLSKTKEIQEWRRSFIIAAS FAVPVFLISMILPMYLPGIDFGRFALVPGLYLGDVVCLALTIPVQFGIGRRFYVTSFKSLKHRSPTMDVLVMLGT SAAFFYSCFTMIMSLCSADHGRPSTVFDTSTMLITFITLGRWLENRAKGQTSAALSRLMCLTPSMTTIYEDPIAA EKLAERWTSKPVHGAPEQPTLGDDMTVNQKCIPTELIQVGDIVILHPGDKVSADGVIIRGESYVDESMISGEALP IHKKKGSQVIAGTVNGTNSIDFKVIRAGKDTQLSQIVKLVQDAQTSRAPIQRMADIVAGYFVPTIIGLGLITFFG WMFLSHVLAHPPTIFEMAGSGGRVMVCLKLCISVIVFACPCALGLSTPTAVMVGTGVGAEHGILVKGGAVLEAAT KVTHVVFDKTGTLTTGRMSVAHTRIEPQWAMNDWRRQLWWLVVGLAETGSEHPIGRAIVSAAITESGHAGEDGLP GSTGDVDNYVGKGVSAVVEPTSSGQRIRHHVLLGNARFLRSQDVPVPADADPDSAEPVEDPEADIPKPGVTGAGT TRIHVAIDNRYAGTISLRDTVKETAVAAVAALHRMGITTSMVTGDTLSTAISIATAVGIPTATIHASVSPSEKRS IVSALQEKGERVAMVGDGINDSPALATASVGIALASGTDVAVEAADIVLMRPDDLLSVPASLSLSRSVFRRIKLN LIWACMYNVIGLPFAMGLFLPFTGFMLPPMAAGGAMALSSVSVVVSSLLLKFWTRPSWMEVERLEKEVQSGAISA AGVAPRKGSWWPSTTIFSNSPRSLRRRVGNVFSSLWSLVTGKGPMPADRGDDGYVPLQTVESPV*
Coding	>Pro_DTO377G3_2|g7520.t1 ATGTTATCTACAAATCCGCACGCCGGCGGGGCCGGTCGACCCGCACTGGCCACTACAACTCTCAAGATCGACGGA ATGACTTGCGGAGCTTGCACATCAGCCGTAGAGGGCGCGTTTCAAGGGGTAGACGGTGCGCACGATGTGTCTGTC AGTCTCATCATGGGCAGGGCCACTGTACAACATGATCCGTCAGTGTTACCACCTGCGAAGGTCGCAGAGATGATT GAGGACCGCGGGTTCGATGCGACAGTACTTTCGACCGAGGAACAAAGGAACCCCGACTCTACTTCTTCTTCTCCA GCTATGAGACTATCGGTGACCACCCTAGCGATTGAGGGGATGACATGCGGGGCATGTACGTCTGCTGTGGAAAGC GGGTTGAACGATGTCAGCGGTGTGAACTCCGTAGACGTATCACTACTTTCCGAGCGCGCAGTCGTGGAACATGAT GCAGGCATCATCACCCCGGAGCAGATCGCAGAGCTCATTGAAGATCGAGGTTTTGGAGCGCGAGTGCTGGATACT GCTCTAGTGGGCTCCAAGGAGCCACCTGCACCGGCTGGCTCGGAAGAGAAATCTGGACTTCTAGTCACCACGATC GCAATCGGCGGTATGACATGCGGCGCTTGCACATCTAGCGTACAGGGTGCCTTGGGCAGTGTGGATGGGGTAATC CAGTTCAACATCAGTCTTCTGGCTGAACGAGCGGTTGTCGTGCACGACCCAACCATACTCCCTGCCAGCAAAATT CCAGAGCTTGTTGAAGATGCTGGATTTGATGCGTCAATCGTTTCATCAGAGGCGCAGGCATCAATTTCCAAAAAG ACACAGCAGATAAATTTGAGCTTGCATGGGCTGCGGGACGGCGTTTCTGCCACTGCCTTGGAGGACAATATTTTA CAGCATTCCGGTGTTCATTCAGCATCAATAAAAATGGCTACCTCTCGTATGGCCATTTCCTTCGACCCATCCACA ATCGGAATCCGGTCTATTGTGGAAATAATTGAGGCTGCTGGTTACAACGCCTTGATTGTCGACTCAGATGATACC AACGCACAGCTACAGTCATTGTCCAAAACAAAGGAAATCCAAGAATGGAGAAGATCCTTCATCATCGCCGCATCT TTTGCGGTTCCCGTGTTCCTTATCAGCATGATTCTTCCGATGTATTTGCCCGGAATTGACTTTGGCCGCTTTGCA CTCGTCCCGGGCCTATATCTCGGAGATGTAGTCTGTCTTGCTCTTACCATTCCGGTGCAATTCGGCATTGGCAGA CGATTCTATGTCACCAGCTTCAAGTCCCTCAAGCATCGGTCCCCAACCATGGACGTTCTCGTAATGCTGGGCACG TCCGCTGCCTTCTTTTACAGCTGTTTCACCATGATCATGTCTCTTTGCAGCGCGGACCACGGTCGTCCTAGCACC GTGTTCGACACCAGTACGATGCTTATCACCTTCATTACTTTGGGACGGTGGCTAGAGAACCGAGCCAAGGGCCAA ACTTCCGCTGCTCTTTCCAGGCTCATGTGTCTGACCCCGTCTATGACTACTATCTACGAAGATCCCATTGCGGCA GAGAAACTGGCTGAGCGCTGGACCTCCAAACCTGTACATGGCGCGCCTGAGCAACCCACGTTGGGTGATGATATG ACGGTGAATCAAAAGTGCATTCCCACCGAGCTGATTCAAGTCGGTGATATCGTTATCCTCCATCCAGGAGATAAG GTGTCTGCGGACGGCGTGATCATCCGGGGCGAAAGCTATGTTGATGAAAGTATGATCAGTGGAGAGGCACTACCT ATCCACAAGAAGAAAGGCAGTCAGGTCATTGCTGGAACCGTGAACGGCACAAACTCAATTGATTTCAAAGTCATT CGAGCCGGCAAGGATACCCAATTGAGCCAGATTGTAAAGTTGGTACAGGATGCGCAGACGAGCCGTGCTCCGATT CAGCGCATGGCTGATATCGTTGCTGGTTACTTTGTTCCCACCATCATCGGTCTTGGTTTGATAACATTCTTTGGT TGGATGTTCCTCAGTCATGTATTAGCTCATCCCCCTACAATATTTGAAATGGCAGGCAGTGGTGGCCGAGTCATG GTCTGCTTGAAGCTGTGCATTTCGGTCATTGTCTTTGCGTGTCCCTGTGCTTTAGGTCTGAGCACCCCGACCGCA GTCATGGTTGGAACCGGCGTCGGCGCGGAACATGGTATACTCGTCAAGGGAGGTGCCGTGCTAGAAGCTGCCACA AAAGTTACTCATGTTGTCTTTGATAAGACGGGCACCCTGACTACAGGTCGGATGAGCGTGGCTCACACCCGAATT GAACCTCAATGGGCGATGAATGACTGGCGCCGTCAGCTGTGGTGGCTTGTTGTCGGTCTCGCAGAGACAGGAAGT GAACATCCGATCGGCCGTGCGATCGTTTCTGCGGCCATAACCGAATCAGGCCACGCCGGAGAAGATGGGTTGCCA GGGAGCACGGGCGACGTTGACAACTATGTTGGTAAGGGTGTCTCCGCCGTCGTCGAACCTACATCTAGTGGCCAG CGTATCCGGCACCATGTCCTCCTTGGTAACGCCAGATTTCTCCGGTCCCAAGATGTCCCTGTACCCGCTGACGCA GATCCCGACTCTGCGGAACCTGTCGAAGACCCGGAAGCTGACATCCCCAAGCCGGGTGTCACCGGGGCCGGCACT ACACGCATCCACGTTGCAATTGACAACCGCTATGCCGGAACCATCTCCCTCCGGGATACAGTGAAAGAGACAGCC GTGGCAGCAGTAGCGGCCCTGCATCGCATGGGCATCACAACCTCCATGGTAACAGGCGACACGCTCTCAACAGCG ATCTCAATCGCCACAGCAGTCGGCATCCCAACCGCCACAATACATGCCTCCGTCTCCCCATCCGAGAAACGCTCA ATCGTCTCCGCCCTCCAAGAAAAAGGCGAGCGCGTTGCCATGGTGGGCGACGGCATCAACGACTCCCCCGCATTG GCCACAGCATCCGTCGGAATCGCCCTCGCATCCGGCACAGACGTGGCCGTCGAGGCTGCTGATATTGTCCTCATG CGCCCGGACGATCTACTCTCTGTACCAGCCAGTCTCTCCCTCTCGCGCTCGGTCTTCAGACGCATCAAGTTGAAC TTAATATGGGCTTGCATGTACAATGTCATCGGCCTTCCATTCGCCATGGGCCTTTTCCTGCCCTTCACAGGCTTC ATGCTACCCCCCATGGCCGCCGGTGGTGCCATGGCTCTTTCCAGTGTGTCTGTCGTTGTTAGTAGTCTGCTGTTG AAATTCTGGACTCGCCCATCTTGGATGGAGGTTGAGCGTCTTGAGAAGGAGGTCCAGTCCGGTGCAATCTCTGCA GCTGGTGTGGCGCCTCGTAAGGGGAGCTGGTGGCCTTCTACTACTATTTTCTCTAATAGCCCGCGCTCTCTACGT CGTCGTGTTGGGAACGTTTTCTCTTCGCTTTGGTCTCTCGTTACTGGCAAAGGACCCATGCCGGCTGACCGGGGT GATGATGGTTATGTTCCGCTGCAGACAGTTGAGTCGCCTGTTTAA
Transcript	>Pro_DTO377G3_2|g7520.t1 ATGTTATCTACAAATCCGCACGCCGGCGGGGCCGGTCGACCCGCACTGGCCACTACAACTCTCAAGATCGACGGA ATGACTTGCGGAGCTTGCACATCAGCCGTAGAGGGCGCGTTTCAAGGGGTAGACGGTGCGCACGATGTGTCTGTC AGTCTCATCATGGGCAGGGCCACTGTACAACATGATCCGTCAGTGTTACCACCTGCGAAGGTCGCAGAGATGATT GAGGACCGCGGGTTCGATGCGACAGTACTTTCGACCGAGGAACAAAGGAACCCCGACTCTACTTCTTCTTCTCCA GCTATGAGACTATCGGTGACCACCCTAGCGATTGAGGGGATGACATGCGGGGCATGTACGTCTGCTGTGGAAAGC GGGTTGAACGATGTCAGCGGTGTGAACTCCGTAGACGTATCACTACTTTCCGAGCGCGCAGTCGTGGAACATGAT GCAGGCATCATCACCCCGGAGCAGATCGCAGAGCTCATTGAAGATCGAGGTTTTGGAGCGCGAGTGCTGGATACT GCTCTAGTGGGCTCCAAGGAGCCACCTGCACCGGCTGGCTCGGAAGAGAAATCTGGACTTCTAGTCACCACGATC GCAATCGGCGGTATGACATGCGGCGCTTGCACATCTAGCGTACAGGGTGCCTTGGGCAGTGTGGATGGGGTAATC CAGTTCAACATCAGTCTTCTGGCTGAACGAGCGGTTGTCGTGCACGACCCAACCATACTCCCTGCCAGCAAAATT CCAGAGCTTGTTGAAGATGCTGGATTTGATGCGTCAATCGTTTCATCAGAGGCGCAGGCATCAATTTCCAAAAAG ACACAGCAGATAAATTTGAGCTTGCATGGGCTGCGGGACGGCGTTTCTGCCACTGCCTTGGAGGACAATATTTTA CAGCATTCCGGTGTTCATTCAGCATCAATAAAAATGGCTACCTCTCGTATGGCCATTTCCTTCGACCCATCCACA ATCGGAATCCGGTCTATTGTGGAAATAATTGAGGCTGCTGGTTACAACGCCTTGATTGTCGACTCAGATGATACC AACGCACAGCTACAGTCATTGTCCAAAACAAAGGAAATCCAAGAATGGAGAAGATCCTTCATCATCGCCGCATCT TTTGCGGTTCCCGTGTTCCTTATCAGCATGATTCTTCCGATGTATTTGCCCGGAATTGACTTTGGCCGCTTTGCA CTCGTCCCGGGCCTATATCTCGGAGATGTAGTCTGTCTTGCTCTTACCATTCCGGTGCAATTCGGCATTGGCAGA CGATTCTATGTCACCAGCTTCAAGTCCCTCAAGCATCGGTCCCCAACCATGGACGTTCTCGTAATGCTGGGCACG TCCGCTGCCTTCTTTTACAGCTGTTTCACCATGATCATGTCTCTTTGCAGCGCGGACCACGGTCGTCCTAGCACC GTGTTCGACACCAGTACGATGCTTATCACCTTCATTACTTTGGGACGGTGGCTAGAGAACCGAGCCAAGGGCCAA ACTTCCGCTGCTCTTTCCAGGCTCATGTGTCTGACCCCGTCTATGACTACTATCTACGAAGATCCCATTGCGGCA GAGAAACTGGCTGAGCGCTGGACCTCCAAACCTGTACATGGCGCGCCTGAGCAACCCACGTTGGGTGATGATATG ACGGTGAATCAAAAGTGCATTCCCACCGAGCTGATTCAAGTCGGTGATATCGTTATCCTCCATCCAGGAGATAAG GTGTCTGCGGACGGCGTGATCATCCGGGGCGAAAGCTATGTTGATGAAAGTATGATCAGTGGAGAGGCACTACCT ATCCACAAGAAGAAAGGCAGTCAGGTCATTGCTGGAACCGTGAACGGCACAAACTCAATTGATTTCAAAGTCATT CGAGCCGGCAAGGATACCCAATTGAGCCAGATTGTAAAGTTGGTACAGGATGCGCAGACGAGCCGTGCTCCGATT CAGCGCATGGCTGATATCGTTGCTGGTTACTTTGTTCCCACCATCATCGGTCTTGGTTTGATAACATTCTTTGGT TGGATGTTCCTCAGTCATGTATTAGCTCATCCCCCTACAATATTTGAAATGGCAGGCAGTGGTGGCCGAGTCATG GTCTGCTTGAAGCTGTGCATTTCGGTCATTGTCTTTGCGTGTCCCTGTGCTTTAGGTCTGAGCACCCCGACCGCA GTCATGGTTGGAACCGGCGTCGGCGCGGAACATGGTATACTCGTCAAGGGAGGTGCCGTGCTAGAAGCTGCCACA AAAGTTACTCATGTTGTCTTTGATAAGACGGGCACCCTGACTACAGGTCGGATGAGCGTGGCTCACACCCGAATT GAACCTCAATGGGCGATGAATGACTGGCGCCGTCAGCTGTGGTGGCTTGTTGTCGGTCTCGCAGAGACAGGAAGT GAACATCCGATCGGCCGTGCGATCGTTTCTGCGGCCATAACCGAATCAGGCCACGCCGGAGAAGATGGGTTGCCA GGGAGCACGGGCGACGTTGACAACTATGTTGGTAAGGGTGTCTCCGCCGTCGTCGAACCTACATCTAGTGGCCAG CGTATCCGGCACCATGTCCTCCTTGGTAACGCCAGATTTCTCCGGTCCCAAGATGTCCCTGTACCCGCTGACGCA GATCCCGACTCTGCGGAACCTGTCGAAGACCCGGAAGCTGACATCCCCAAGCCGGGTGTCACCGGGGCCGGCACT ACACGCATCCACGTTGCAATTGACAACCGCTATGCCGGAACCATCTCCCTCCGGGATACAGTGAAAGAGACAGCC GTGGCAGCAGTAGCGGCCCTGCATCGCATGGGCATCACAACCTCCATGGTAACAGGCGACACGCTCTCAACAGCG ATCTCAATCGCCACAGCAGTCGGCATCCCAACCGCCACAATACATGCCTCCGTCTCCCCATCCGAGAAACGCTCA ATCGTCTCCGCCCTCCAAGAAAAAGGCGAGCGCGTTGCCATGGTGGGCGACGGCATCAACGACTCCCCCGCATTG GCCACAGCATCCGTCGGAATCGCCCTCGCATCCGGCACAGACGTGGCCGTCGAGGCTGCTGATATTGTCCTCATG CGCCCGGACGATCTACTCTCTGTACCAGCCAGTCTCTCCCTCTCGCGCTCGGTCTTCAGACGCATCAAGTTGAAC TTAATATGGGCTTGCATGTACAATGTCATCGGCCTTCCATTCGCCATGGGCCTTTTCCTGCCCTTCACAGGCTTC ATGCTACCCCCCATGGCCGCCGGTGGTGCCATGGCTCTTTCCAGTGTGTCTGTCGTTGTTAGTAGTCTGCTGTTG AAATTCTGGACTCGCCCATCTTGGATGGAGGTTGAGCGTCTTGAGAAGGAGGTCCAGTCCGGTGCAATCTCTGCA GCTGGTGTGGCGCCTCGTAAGGGGAGCTGGTGGCCTTCTACTACTATTTTCTCTAATAGCCCGCGCTCTCTACGT CGTCGTGTTGGGAACGTTTTCTCTTCGCTTTGGTCTCTCGTTACTGGCAAAGGACCCATGCCGGCTGACCGGGGT GATGATGGTTATGTTCCGCTGCAGACAGTTGAGTCGCCTGTTTAA
Gene	>Pro_DTO377G3_2|g7520.t1 ATGTTATCTACAAATCCGCACGCCGGCGGGGCCGGTCGACCCGCACTGGCCACTACAACTCTCAAGATCGACGGA ATGACTTGCGGAGCTTGCACATCAGCCGTAGAGGGCGCGTTTCAAGGGGTAGACGGTGCGCACGATGTGTCTGTC AGTCTCATCATGGGCAGGGCCACTGTACAACATGATCCGTCAGTGTTACCACCTGCGAAGGTCGCAGAGATGATT GAGGACCGCGGGTTCGATGCGACAGTACTTTCGACCGAGGAACAAAGGAACCCCGACTCTACTTCTTCTTCTCCA GCTATGAGACTATCGGTGACCACCCTAGCGATTGAGGGGATGACATGCGGGGCATGTACGTCTGCTGTGGAAAGC GGGTTGAACGATGTCAGCGGTGTGAACTCCGTAGACGTATCACTACTTTCCGAGCGCGCAGTCGTGGAACATGAT GCAGGCATCATCACCCCGGAGCAGATCGCAGAGCTCATTGAAGATCGAGGTTTTGGAGCGCGAGTGCTGGATACT GCTCTAGTGGGCTCCAAGGAGCCACCTGCACCGGCTGGCTCGGAAGAGAAATCTGGACTTCTAGTCACCACGATC GCAATCGGCGGTATGACATGCGGCGCTTGCACATCTAGCGTACAGGGTGCCTTGGGCAGTGTGGATGGGGTAATC CAGTTCAACATCAGTCTTCTGGCTGAACGAGCGGTTGTCGTGCACGACCCAACCATACTCCCTGCCAGCAAAATT CCAGAGCTTGTTGAAGATGCTGGATTTGATGCGTCAATCGTTTCATCAGAGGCGCAGGCATCAATTTCCAAAAAG ACACAGCAGATAAATTTGAGCTTGCATGGGCTGCGGGACGGCGTTTCTGCCACTGCCTTGGAGGACAATATTTTA CAGCATTCCGGTGTTCATTCAGCATCAATAAAAATGGCTACCTCTCGTATGGCCATTTCCTTCGACCCATCCACA ATCGGAATCCGGTCTATTGTGGAAATAATTGAGGCTGCTGGTTACAACGCCTTGATTGTCGACTCAGATGATACC AACGCACAGCTACAGTCATTGTCCAAAACAAAGGAAATCCAAGAATGGAGAAGATCCTTCATCATCGCCGCATCT TTTGCGGTTCCCGTGTTCCTTATCAGCATGATTCTTCCGATGTATTTGCCCGGAATTGACTTTGGCCGCTTTGCA CTCGTCCCGGGCCTATATCTCGGAGATGTAGTCTGTCTTGCTCTTACCATTCCGGTGCAATTCGGCATTGGCAGA CGATTCTATGTCACCAGCTTCAAGTCCCTCAAGCATCGGTCCCCAACCATGGACGTTCTCGTAATGCTGGGCACG TCCGCTGCCTTCTTTTACAGCTGTTTCACCATGATCATGTCTCTTTGCAGCGCGGACCACGGTCGTCCTAGCACC GTGTTCGACACCAGTACGATGCTTATCACCTTCATTACTTTGGGACGGTGGCTAGAGAACCGAGCCAAGGGCCAA ACTTCCGCTGCTCTTTCCAGGCTCATGTGTCTGACCCCGTCTATGACTACTATCTACGAAGATCCCATTGCGGCA GAGAAACTGGCTGAGCGCTGGACCTCCAAACCTGTACATGGCGCGCCTGAGCAACCCACGTTGGGTGATGATATG ACGGTGAATCAAAAGTGCATTCCCACCGAGCTGATTCAAGTCGGTGATATCGTTATCCTCCATCCAGGAGATAAG GTGTCTGCGGACGGCGTGATCATCCGGGGCGAAAGCTATGTTGATGAAAGTATGATCAGTGGAGAGGCACTACCT ATCCACAAGAAGAAAGGCAGTCAGGTCATTGCTGGAACCGTGAACGGCACAAACTCAATTGATTTCAAAGTCATT CGAGCCGGCAAGGATACCCAATTGAGCCAGATTGTAAAGTTGGTACAGGATGCGCAGACGAGCCGTGCTCCGATT CAGCGCATGGCTGATATCGTTGCTGGTTACTTTGTTCCCACCATCATCGGTCTTGGTTTGATAACATTCTTTGGT TGGATGTTCCTCAGTCATGTATTAGCTCATCCCCCTACAATATTTGAAATGGCAGGCAGTGGTGGCCGAGTCATG GTCTGCTTGAAGCTGTGCATTTCGGTCATTGTCTTTGCGTGTCCCTGTGCTTTAGGTCTGAGCACCCCGACCGCA GTCATGGTTGGAACCGGCGTCGGCGCGGAACATGGTATACTCGTCAAGGGAGGTGCCGTGCTAGAAGCTGCCACA AAAGTTACTCATGTTGTCTTTGATAAGACGGGCACCCTGACTACAGGTCGGATGAGCGTGGCTCACACCCGAATT GAACCTCAATGGGCGATGAATGACTGGCGCCGTCAGCTGTGGTGGCTTGTTGTCGGTCTCGCAGAGACAGGAAGT GAACATCCGATCGGCCGTGCGATCGTTTCTGCGGCCATAACCGAATCAGGCCACGCCGGAGAAGATGGGTTGCCA GGGAGCACGGGCGACGTTGACAACTATGTTGGTAAGGGTGTCTCCGCCGTCGTCGAACCTACATCTAGTGGCCAG CGTATCCGGCACCATGTCCTCCTTGGTAACGCCAGATTTCTCCGGTCCCAAGATGTCCCTGTACCCGCTGACGCA GATCCCGACTCTGCGGAACCTGTCGAAGACCCGGAAGCTGACATCCCCAAGCCGGGTGTCACCGGGGCCGGCACT ACACGCATCCACGTTGCAATTGACAACCGCTATGCCGGAACCATCTCCCTCCGGGATACAGTGAAAGAGACAGCC GTGGCAGCAGTAGCGGCCCTGCATCGCATGGGCATCACAACCTCCATGGTAACAGGCGACACGCTCTCAACAGCG ATCTCAATCGCCACAGCAGTCGGCATCCCAACCGCCACAATACATGCCTCCGTCTCCCCATCCGAGAAACGCTCA ATCGTCTCCGCCCTCCAAGAAAAAGGCGAGCGCGTTGCCATGGTGGGCGACGGCATCAACGACTCCCCCGCATTG GCCACAGCATCCGTCGGAATCGCCCTCGCATCCGGCACAGACGTGGCCGTCGAGGCTGCTGATATTGTCCTCATG CGCCCGGACGATCTACTCTCTGTACCAGCCAGTCTCTCCCTCTCGCGCTCGGTCTTCAGACGCATCAAGTTGAAC TTAATATGGGCTTGCATGTACAATGTCATCGGCCTTCCATTCGCCATGGGCCTTTTCCTGCCCTTCACAGGCTTC ATGCTACCCCCCATGGCCGCCGGTGGTGCCATGGCTCTTTCCAGTGTGTCTGTCGTTGTTAGTAGTCTGCTGTTG AAATTCTGGACTCGCCCATCTTGGATGGAGGTTGAGCGTCTTGAGAAGGAGGTCCAGTCCGGTGCAATCTCTGCA GCTGGTGTGGCGCCTCGTAAGGGGAGCTGGTGGCCTTCTACTACTATTTTCTCTAATAGCCCGCGCTCTCTACGT CGTCGTGTTGGGAACGTTTTCTCTTCGCTTTGGTCTCTCGTTACTGGCAAAGGACCCATGCCGGCTGACCGGGGT GATGATGGTTATGTTCCGCTGCAGACAGTTGAGTCGCCTGTTTAA