Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g7156.t1
Gene name
Location	scaffold_21:208624..212091
Strand	-
Gene length (bp)	3467
Transcript length (bp)	3165
Coding sequence length (bp)	3165
Protein length (aa)	1055

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF10408	Ufd2P_core	Ubiquitin elongating factor core	1.8E-218	327	951
PF04564	U-box	U-box domain	2.1E-25	967	1037

GO

GO Term	Description	Terminal node
GO:0000151	ubiquitin ligase complex	Yes
GO:0016567	protein ubiquitination	Yes
GO:0004842	ubiquitin-protein transferase activity	Yes
GO:0006511	ubiquitin-dependent protein catabolic process	Yes
GO:0034450	ubiquitin-ubiquitin ligase activity	Yes
GO:0032991	protein-containing complex	No
GO:0044248	cellular catabolic process	No
GO:0009056	catabolic process	No
GO:0009057	macromolecule catabolic process	No
GO:0008152	metabolic process	No
GO:0043170	macromolecule metabolic process	No
GO:0044260	cellular macromolecule metabolic process	No
GO:0016740	transferase activity	No
GO:0005575	cellular_component	No
GO:0071704	organic substance metabolic process	No
GO:0036211	protein modification process	No
GO:0032446	protein modification by small protein conjugation	No
GO:0008150	biological_process	No
GO:0019538	protein metabolic process	No
GO:0019787	ubiquitin-like protein transferase activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0003824	catalytic activity	No
GO:0140535	intracellular protein-containing complex	No
GO:0061659	ubiquitin-like protein ligase activity	No
GO:1902494	catalytic complex	No
GO:0044238	primary metabolic process	No
GO:0051603	proteolysis involved in protein catabolic process	No
GO:0009987	cellular process	No
GO:0061630	ubiquitin protein ligase activity	No
GO:1901564	organonitrogen compound metabolic process	No
GO:0044237	cellular metabolic process	No
GO:1901575	organic substance catabolic process	No
GO:1990234	transferase complex	No
GO:0006508	proteolysis	No
GO:0019941	modification-dependent protein catabolic process	No
GO:0006807	nitrogen compound metabolic process	No
GO:0043632	modification-dependent macromolecule catabolic process	No
GO:0070647	protein modification by small protein conjugation or removal	No
GO:0003674	molecular_function	No
GO:0044265	cellular macromolecule catabolic process	No
GO:0043412	macromolecule modification	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 52	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g7156.t1 MSDTLSDADKIRNKRLAKLSNPGQSSDGASESTQSSSNTSPSQSPLSVQPPSRLFNAPPTPQQSEGKRIKITPAA ASSEQPRTAAPSAPSTPPPQKIESIEAFEDRTLSAVFRVTLKEEGHRDIHGSRTYLPGLRSELQDEGQDLRIQVE VLDQALLEAASKAEKQRPLDYLLPCWKRITKLYKGLRRTGDDDPKYQVLCEARRLCMSYCIFAITMPEMFGSEWS PQSSLASYLLIDPEDDRGIDFEFINEAVRRFDEDDSVKPAFISAVEQLSAQLSSMDVNDDYKPYAIALRNLVRHG SIAAAITESSIFNNTRDPAQFEKATLLGPWFRLSPLQANVTLSYFSSPKTRDQAYISNAQRSLRMTQQMLSSDLL DVINHLIRASKEARDRVLDWFATAMNINHKRRAMQVDPAQVSSDGFMFNITTCLDQLCEPFMDAAFTKIDRVDAD YLHRDSRVDMRDETKINADQHASDAFYSKKVEGTSNFITEVFFLTVAAHHYGSESLTSKMEQLEKDVRQMESTIT KFELERVRWLNNPQQLRTFDTALKKYKDKLELGIALKYSLQGVLFDEQWQARSMLFMRYVTVWLLRLVSGKNFPK EQVTLPLPEEQPEVFKCLPEYFLEDVVSNFKFIMWCMPQIITATQGDELVMLCITFLECSTYIKNPYLKAGLISI LFRGTWKRPGGASGVLVDLLNSMPFANEHLLHAVMKFYIEAEFTGTHSQFYDKFNIRYEIFQIIKCIWPNTLYRE KLSLQANQNLDFFVQFVNLLLNDVTYVLDESFGAFKTIHNTQTELNTQGNSMDAATRQQREENLSSAQRSAKSYM QLTNQTVAMLKLFTEALADSFTMPEIVQRLADMLDYNLDAMVGPKSSNLRVDNLQEYGFNPRALLSEIVDVYLNL IGKENFILAVARDGRSYKPANFEKAADIIRKWSLKSPEQLHHWSELQKKVQAAKEADDQAEEDMGEIPEEFLDPL MYSLMDDPVILPSSRIAIDRATIRSHLLSDPHDPFNRVPLKIEDVVADTELKAKIEAFKNEKLAGKRREMVHDRM DTSN*
Coding	>Pro_DTO377G3_2|g7156.t1 ATGTCGGACACACTTTCCGACGCAGACAAGATTCGCAACAAGCGACTTGCAAAGCTCTCAAACCCAGGCCAGTCC TCCGACGGTGCCTCCGAATCGACACAGAGCTCATCTAACACATCTCCGTCACAATCACCACTGTCGGTGCAGCCA CCGAGTCGCCTTTTCAACGCGCCACCAACCCCGCAGCAGTCAGAAGGGAAGCGGATCAAGATCACACCGGCCGCG GCTTCATCGGAGCAACCACGAACCGCCGCTCCCTCAGCCCCGAGCACCCCTCCGCCACAGAAAATCGAAAGCATA GAGGCCTTCGAAGACCGAACACTAAGTGCCGTGTTCAGAGTGACCCTCAAGGAAGAAGGGCATCGTGACATACAT GGCAGCCGTACATACTTGCCTGGGCTTCGGAGCGAACTGCAGGATGAGGGTCAGGACTTGCGCATCCAGGTTGAG GTTCTGGACCAGGCCCTCCTAGAGGCTGCGTCAAAGGCCGAGAAGCAGCGTCCACTCGACTATCTGCTGCCGTGC TGGAAGCGCATCACAAAACTGTACAAGGGATTGAGGCGGACGGGAGATGATGACCCGAAGTATCAGGTTCTGTGT GAGGCACGGCGCCTGTGTATGAGCTATTGTATCTTTGCGATTACAATGCCAGAGATGTTTGGGAGCGAATGGTCC CCTCAATCATCGTTAGCCTCGTATCTTCTCATCGACCCCGAGGATGATAGAGGAATTGATTTCGAGTTTATCAAC GAAGCTGTGAGAAGATTCGACGAAGACGACTCCGTCAAGCCTGCCTTCATCTCTGCCGTCGAGCAGTTGAGCGCG CAGCTCTCTTCTATGGACGTTAACGATGACTACAAGCCATACGCCATTGCTCTTCGAAACCTTGTTCGCCACGGT TCCATCGCGGCAGCAATCACAGAATCGTCCATTTTCAACAACACAAGGGACCCTGCTCAATTCGAGAAAGCCACT CTTTTGGGTCCATGGTTCCGCCTCTCACCCCTTCAAGCTAATGTTACCCTGTCCTATTTCTCTAGCCCCAAGACC AGGGACCAGGCATACATTTCCAATGCCCAGCGATCGCTCCGAATGACGCAGCAGATGCTCAGTTCTGATCTTCTT GATGTTATCAACCACCTGATCCGGGCTTCGAAAGAGGCTCGAGATCGTGTTTTAGATTGGTTCGCGACTGCTATG AACATCAACCACAAACGACGGGCCATGCAGGTTGACCCTGCGCAAGTATCCTCTGACGGCTTCATGTTCAATATT ACAACTTGCCTCGACCAGCTCTGTGAGCCGTTCATGGATGCAGCATTCACCAAAATCGACAGAGTTGATGCAGAT TATCTCCACCGCGATTCTCGAGTTGACATGCGGGATGAGACCAAAATCAATGCCGATCAGCATGCCTCCGACGCT TTCTATTCTAAGAAGGTTGAGGGAACTTCAAACTTTATCACCGAAGTATTCTTCCTGACTGTCGCCGCCCATCAC TACGGCAGTGAATCATTGACGTCAAAGATGGAGCAACTCGAGAAAGATGTGCGACAGATGGAGAGTACAATCACT AAATTTGAACTTGAGCGGGTTCGTTGGCTCAACAATCCACAGCAATTGCGCACCTTCGATACGGCCCTGAAGAAG TACAAAGACAAGCTCGAACTGGGCATCGCTCTCAAATACAGTCTCCAAGGTGTGTTGTTCGACGAGCAGTGGCAG GCTCGTTCTATGCTATTCATGCGATATGTTACCGTGTGGCTTCTGAGACTTGTCTCTGGAAAGAACTTCCCCAAA GAGCAAGTTACCCTGCCTCTTCCAGAGGAGCAGCCCGAAGTCTTCAAATGTCTACCAGAGTACTTCTTGGAGGAT GTTGTCAGTAACTTCAAGTTTATCATGTGGTGCATGCCACAGATCATTACGGCCACCCAGGGAGATGAGCTGGTA ATGCTGTGCATCACATTCCTAGAGTGCTCGACCTATATTAAGAATCCCTATCTGAAAGCCGGACTGATCTCCATT CTGTTCCGAGGCACCTGGAAGCGCCCTGGTGGCGCCAGTGGTGTTTTAGTCGACTTGCTCAACAGCATGCCATTT GCCAACGAACATCTCCTCCATGCGGTCATGAAATTCTATATTGAGGCAGAGTTCACGGGAACACATTCCCAATTC TACGACAAGTTTAACATCCGTTACGAGATCTTCCAGATCATCAAATGCATCTGGCCCAACACTCTGTATCGGGAG AAGTTGTCCCTTCAAGCCAATCAGAACCTGGATTTCTTCGTCCAATTCGTTAACCTTCTACTAAACGATGTGACT TACGTCCTCGATGAATCTTTCGGTGCTTTCAAGACTATCCACAACACTCAGACCGAGCTGAATACACAGGGCAAC TCAATGGATGCCGCAACCCGCCAACAGCGGGAGGAGAACCTGTCATCAGCGCAGCGCAGCGCCAAGAGCTACATG CAACTGACTAATCAAACCGTGGCAATGCTCAAGCTATTCACTGAGGCGCTTGCTGACTCGTTCACAATGCCTGAA ATTGTGCAGCGACTGGCAGACATGCTGGACTACAATCTCGACGCAATGGTGGGACCCAAGAGCTCCAATCTCCGA GTGGACAACCTGCAGGAATATGGCTTCAATCCCCGCGCTCTTCTGAGTGAGATTGTCGACGTCTATCTTAATCTG ATCGGCAAGGAAAACTTCATCCTGGCTGTTGCCCGTGATGGCCGATCCTACAAGCCAGCCAATTTCGAGAAGGCG GCTGATATTATCCGAAAGTGGTCGCTGAAATCCCCCGAGCAGCTTCACCACTGGAGTGAGCTGCAGAAGAAGGTC CAGGCTGCCAAGGAGGCCGATGATCAAGCGGAGGAAGACATGGGCGAGATCCCTGAAGAGTTCCTCGATCCTCTT ATGTATTCCCTCATGGATGATCCCGTCATACTTCCCAGCTCACGGATCGCCATCGACCGCGCTACAATTCGCTCG CATCTCCTGAGTGACCCCCACGATCCATTTAACCGTGTCCCATTGAAGATTGAAGATGTAGTAGCTGATACCGAA CTTAAAGCCAAGATTGAGGCGTTCAAAAATGAGAAATTAGCTGGCAAACGGAGGGAAATGGTGCATGATCGGATG GACACTTCAAATTAA
Transcript	>Pro_DTO377G3_2|g7156.t1 ATGTCGGACACACTTTCCGACGCAGACAAGATTCGCAACAAGCGACTTGCAAAGCTCTCAAACCCAGGCCAGTCC TCCGACGGTGCCTCCGAATCGACACAGAGCTCATCTAACACATCTCCGTCACAATCACCACTGTCGGTGCAGCCA CCGAGTCGCCTTTTCAACGCGCCACCAACCCCGCAGCAGTCAGAAGGGAAGCGGATCAAGATCACACCGGCCGCG GCTTCATCGGAGCAACCACGAACCGCCGCTCCCTCAGCCCCGAGCACCCCTCCGCCACAGAAAATCGAAAGCATA GAGGCCTTCGAAGACCGAACACTAAGTGCCGTGTTCAGAGTGACCCTCAAGGAAGAAGGGCATCGTGACATACAT GGCAGCCGTACATACTTGCCTGGGCTTCGGAGCGAACTGCAGGATGAGGGTCAGGACTTGCGCATCCAGGTTGAG GTTCTGGACCAGGCCCTCCTAGAGGCTGCGTCAAAGGCCGAGAAGCAGCGTCCACTCGACTATCTGCTGCCGTGC TGGAAGCGCATCACAAAACTGTACAAGGGATTGAGGCGGACGGGAGATGATGACCCGAAGTATCAGGTTCTGTGT GAGGCACGGCGCCTGTGTATGAGCTATTGTATCTTTGCGATTACAATGCCAGAGATGTTTGGGAGCGAATGGTCC CCTCAATCATCGTTAGCCTCGTATCTTCTCATCGACCCCGAGGATGATAGAGGAATTGATTTCGAGTTTATCAAC GAAGCTGTGAGAAGATTCGACGAAGACGACTCCGTCAAGCCTGCCTTCATCTCTGCCGTCGAGCAGTTGAGCGCG CAGCTCTCTTCTATGGACGTTAACGATGACTACAAGCCATACGCCATTGCTCTTCGAAACCTTGTTCGCCACGGT TCCATCGCGGCAGCAATCACAGAATCGTCCATTTTCAACAACACAAGGGACCCTGCTCAATTCGAGAAAGCCACT CTTTTGGGTCCATGGTTCCGCCTCTCACCCCTTCAAGCTAATGTTACCCTGTCCTATTTCTCTAGCCCCAAGACC AGGGACCAGGCATACATTTCCAATGCCCAGCGATCGCTCCGAATGACGCAGCAGATGCTCAGTTCTGATCTTCTT GATGTTATCAACCACCTGATCCGGGCTTCGAAAGAGGCTCGAGATCGTGTTTTAGATTGGTTCGCGACTGCTATG AACATCAACCACAAACGACGGGCCATGCAGGTTGACCCTGCGCAAGTATCCTCTGACGGCTTCATGTTCAATATT ACAACTTGCCTCGACCAGCTCTGTGAGCCGTTCATGGATGCAGCATTCACCAAAATCGACAGAGTTGATGCAGAT TATCTCCACCGCGATTCTCGAGTTGACATGCGGGATGAGACCAAAATCAATGCCGATCAGCATGCCTCCGACGCT TTCTATTCTAAGAAGGTTGAGGGAACTTCAAACTTTATCACCGAAGTATTCTTCCTGACTGTCGCCGCCCATCAC TACGGCAGTGAATCATTGACGTCAAAGATGGAGCAACTCGAGAAAGATGTGCGACAGATGGAGAGTACAATCACT AAATTTGAACTTGAGCGGGTTCGTTGGCTCAACAATCCACAGCAATTGCGCACCTTCGATACGGCCCTGAAGAAG TACAAAGACAAGCTCGAACTGGGCATCGCTCTCAAATACAGTCTCCAAGGTGTGTTGTTCGACGAGCAGTGGCAG GCTCGTTCTATGCTATTCATGCGATATGTTACCGTGTGGCTTCTGAGACTTGTCTCTGGAAAGAACTTCCCCAAA GAGCAAGTTACCCTGCCTCTTCCAGAGGAGCAGCCCGAAGTCTTCAAATGTCTACCAGAGTACTTCTTGGAGGAT GTTGTCAGTAACTTCAAGTTTATCATGTGGTGCATGCCACAGATCATTACGGCCACCCAGGGAGATGAGCTGGTA ATGCTGTGCATCACATTCCTAGAGTGCTCGACCTATATTAAGAATCCCTATCTGAAAGCCGGACTGATCTCCATT CTGTTCCGAGGCACCTGGAAGCGCCCTGGTGGCGCCAGTGGTGTTTTAGTCGACTTGCTCAACAGCATGCCATTT GCCAACGAACATCTCCTCCATGCGGTCATGAAATTCTATATTGAGGCAGAGTTCACGGGAACACATTCCCAATTC TACGACAAGTTTAACATCCGTTACGAGATCTTCCAGATCATCAAATGCATCTGGCCCAACACTCTGTATCGGGAG AAGTTGTCCCTTCAAGCCAATCAGAACCTGGATTTCTTCGTCCAATTCGTTAACCTTCTACTAAACGATGTGACT TACGTCCTCGATGAATCTTTCGGTGCTTTCAAGACTATCCACAACACTCAGACCGAGCTGAATACACAGGGCAAC TCAATGGATGCCGCAACCCGCCAACAGCGGGAGGAGAACCTGTCATCAGCGCAGCGCAGCGCCAAGAGCTACATG CAACTGACTAATCAAACCGTGGCAATGCTCAAGCTATTCACTGAGGCGCTTGCTGACTCGTTCACAATGCCTGAA ATTGTGCAGCGACTGGCAGACATGCTGGACTACAATCTCGACGCAATGGTGGGACCCAAGAGCTCCAATCTCCGA GTGGACAACCTGCAGGAATATGGCTTCAATCCCCGCGCTCTTCTGAGTGAGATTGTCGACGTCTATCTTAATCTG ATCGGCAAGGAAAACTTCATCCTGGCTGTTGCCCGTGATGGCCGATCCTACAAGCCAGCCAATTTCGAGAAGGCG GCTGATATTATCCGAAAGTGGTCGCTGAAATCCCCCGAGCAGCTTCACCACTGGAGTGAGCTGCAGAAGAAGGTC CAGGCTGCCAAGGAGGCCGATGATCAAGCGGAGGAAGACATGGGCGAGATCCCTGAAGAGTTCCTCGATCCTCTT ATGTATTCCCTCATGGATGATCCCGTCATACTTCCCAGCTCACGGATCGCCATCGACCGCGCTACAATTCGCTCG CATCTCCTGAGTGACCCCCACGATCCATTTAACCGTGTCCCATTGAAGATTGAAGATGTAGTAGCTGATACCGAA CTTAAAGCCAAGATTGAGGCGTTCAAAAATGAGAAATTAGCTGGCAAACGGAGGGAAATGGTGCATGATCGGATG GACACTTCAAATTAA
Gene	>Pro_DTO377G3_2|g7156.t1 ATGTCGGACACACTTTCCGACGCAGACAAGGTTAGTTTCTTGTTGTACTCGAGCTATGAAGCTATACCGCCCCCG CAGTGACTCGACTCGAGGACTGACATCTATCTTGATAAAAAAAAGATTCGCAACAAGCGACTTGCAAAGCTCTCA AACCCAGGCCAGTCCTCCGACGGTGCCTCCGAATCGACACAGAGCTCATCTAACACATCTCCGTCACAATCACCA CTGTCGGTGCAGCCACCGAGTCGCCTTTTCAACGCGCCACCAACCCCGCAGCAGTCAGAAGGGAAGCGGATCAAG ATCACACCGGCCGCGGCTTCATCGGAGCAACCACGAACCGCCGCTCCCTCAGCCCCGAGCACCCCTCCGCCACAG AAAATCGAAAGCATAGAGGCCTTCGAAGACCGAACACTAAGTGCCGTGTTCAGAGTGACCCTCAAGGAAGAAGGG CATCGTGACATACATGGCAGCCGTACATACTTGCCTGGGCTTCGGAGCGAACTGCAGGATGAGGGTCAGGACTTG CGCATCCAGGTTGAGGTTCTGGACCAGGCCCTCCTAGAGGCTGCGTCAAAGGCCGAGAAGCAGCGTCCACTCGAC TATCTGCTGCCGTGCTGGAAGCGCATCACAAAACTGTACAAGGGATTGAGGCGGACGGGAGATGATGACCCGAAG TATCAGGTTCTGTGTGAGGCACGGCGCCTGTGTATGAGCTATTGTATCTTTGCGATTACAATGCCAGAGATGTTT GGGTTCGTTCTCTGGAATGCTGCTACACTGGCACTGGATACTGACTGAACTGTAGGAGCGAATGGTCCCCTCAAT CATCGTTAGCCTCGTATCTTCTCATCGACCCCGAGGATGATAGAGGAATTGATTTCGAGTTTATCAACGAAGCTG TGAGAAGATTCGACGAAGACGACTCCGTCAAGCCTGCCTTCATCTCTGCCGTCGAGCAGTTGAGCGCGCAGCTCT CTTCTATGGACGTTAACGATGACTACAAGCCATACGCCATTGTAAGTCAAACGTCACAATTTCCCTGGACCACGT CTGACCAGTTTGTTCAGGCTCTTCGAAACCTTGTTCGCCACGGTTCCATCGCGGCAGCAATCACAGAATCGTCCA TTTTCAACAACACAAGGGACCCTGCTCAATTCGAGAAAGCCACTCTTTTGGGTCCATGGTTCCGCCTCTCACCCC TTCAAGCTAATGTTACCCTGTCCTATTTCTCTAGCCCCAAGACCAGGGACCAGGCATACATTTCCAATGCCCAGC GATCGCTCCGAATGACGCAGCAGATGCTCAGTTCTGATCTTCTTGATGTTATCAACCACCTGATCCGGGCTTCGA AAGAGGCTCGAGATCGTGTTTTAGATTGGTTCGCGACTGCTATGAACATCAACCACAAACGACGGGCCATGCAGG TTGACCCTGCGCAAGTATCCTCTGACGGCTTCATGTTCAATATTACAACTTGCCTCGACCAGCTCTGTGAGCCGT TCATGGATGCAGCATTCACCAAAATCGACAGAGTTGATGCAGATTATCTCCACCGCGATTCTCGAGTTGACATGC GGGATGAGACCAAAATCAATGCCGATCAGCATGCCTCCGACGCTTTCTATTCTAAGAAGGTTGAGGGAACTTCAA ACTTTATCACCGAAGTATTCTTCCTGACTGTCGCCGCCCATCACTACGGCAGTGAATCATTGACGTCAAAGATGG AGCAACTCGAGAAAGATGTGCGACAGATGGAGAGTACAATCACTAAATTTGAACTTGAGCGGGTTCGTTGGCTCA ACAATCCACAGCAATTGCGCACCTTCGATACGGCCCTGAAGAAGTACAAAGACAAGCTCGAACTGGGCATCGCTC TCAAATACAGTCTCCAAGGTGTGTTGTTCGACGAGCAGTGGCAGGCTCGTTCTATGCTATTCATGCGATATGTTA CCGTGTGGCTTCTGAGACTTGTCTCTGGAAAGAACTTCCCCAAAGAGCAAGTTACCCTGCCTCTTCCAGAGGAGC AGCCCGAAGTCTTCAAATGTCTACCAGAGTACTTCTTGGAGGATGTTGTCAGTAACTTCAAGTTTATCATGTGGT GCATGCCACAGATCATTACGGCCACCCAGGGAGATGAGCTGGTAATGCTGTGCATCACATTCCTAGAGTGCTCGA CCTATATTAAGAATCCCTATCTGAAAGCCGGACTGATCTCCATTCTGTTCCGAGGCACCTGGAAGCGCCCTGGTG GCGCCAGTGGTGTTTTAGTCGACTTGCTCAACAGCATGCCATTTGCCAACGAACATCTCCTCCATGCGGTCATGA AATTCTATATTGAGGCAGAGTTCACGGGAACACATTCCCAATTCTACGACAAGTTTAACATCCGTTACGAGATCT TCCAGATCATCAAATGCATCTGGCCCAACACTCTGTATCGGGAGAAGTTGTCCCTTCAAGCCAATCAGAACCTGG ATTTCTTCGTCCAATTCGTTAACCTTCTACTAAACGATGTGACTTACGTCCTCGATGAATCTTTCGGTGCTTTCA AGACTATCCACAACACTCAGACCGAGCTGAATACACAGGGCAACTCAATGGATGCCGCAACCCGCCAACAGCGGG AGGAGAACCTGTCATCAGCGCAGCGCAGCGCCAAGAGCTACATGCAACTGACTAATCAAACCGTGGCAATGCTCA AGCTATTCACTGAGGCGCTTGCTGACTCGTTCACAATGCCTGAAATTGTGCAGCGACTGGCAGACATGCTGGACT ACAATCTCGACGCAATGGTGGGACCCAAGAGCTCCAATCTCCGAGTGGACAACCTGCAGGAATATGGCTTCAATC CCCGCGCTCTTCTGAGTGAGATTGTCGACGTCTATCTTAATCTGATCGGCAAGGAAAACTTCATCCTGGCTGTTG CCCGTGATGGCCGATCCTACAAGCCAGCCAATTTCGAGAAGGCGGCTGATATTATCCGAAAGTGGTCGCTGAAAT CCCCCGAGCAGCTTCACCACTGGAGTGAGCTGCAGAAGAAGGTCCAGGCTGCCAAGGAGGCCGATGATCAAGCGG AGGAAGACATGGGCGAGATCCCTGAAGAGTTCCTCGGTATTTTTCCCTTTTTGAACTATCCCTTTTCGACAGCTG CTAATTTTTTAGATCCTCTTATGTATTCCCTCATGGATGATCCCGTCATACTTCCCAGCTCACGGATCGCCATCG ACCGCGCTACAATTCGCTCGCATCTCCTGAGTGACCCCCACGATCCATTTAACCGTGTCCCATTGAAGATTGAAG ATGTAGTAGCTGGTAAGTAATTTTCTTTCCCAGGTATTGTTCCAATACCAGTATTAACCACCTTTCTAGATACCG AACTTAAAGCCAAGATTGAGGCGTTCAAAAATGAGAAATTAGCTGGCAAACGGAGGGAAATGGTGCATGATCGGA TGGACACTTCAAATTAA