Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g7045.t1
Gene name
Location	scaffold_20:317816..322449
Strand	+
Gene length (bp)	4633
Transcript length (bp)	3090
Coding sequence length (bp)	3090
Protein length (aa)	1030

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF02190	LON_substr_bdg	ATP-dependent protease La (LON) substrate-binding domain	1.0E-25	789	1009
PF00474	SSF	Sodium:solute symporter family	6.9E-16	49	454
PF13923	zf-C3HC4_2	Zinc finger, C3HC4 type (RING finger)	1.1E-11	701	738
PF13920	zf-C3HC4_3	Zinc finger, C3HC4 type (RING finger)	2.3E-08	699	741
PF13639	zf-RING_2	Ring finger domain	2.5E-07	700	739
PF14634	zf-RING_5	zinc-RING finger domain	3.2E-07	701	740
PF13445	zf-RING_UBOX	RING-type zinc-finger	2.1E-07	701	725
PF00097	zf-C3HC4	Zinc finger, C3HC4 type (RING finger)	8.1E-07	701	738

GO

GO Term	Description	Terminal node
GO:0016020	membrane	Yes
GO:0055085	transmembrane transport	Yes
GO:0046872	metal ion binding	Yes
GO:0022857	transmembrane transporter activity	Yes
GO:0008150	biological_process	No
GO:0006810	transport	No
GO:0009987	cellular process	No
GO:0043167	ion binding	No
GO:0005488	binding	No
GO:0043169	cation binding	No
GO:0051234	establishment of localization	No
GO:0110165	cellular anatomical entity	No
GO:0005215	transporter activity	No
GO:0003674	molecular_function	No
GO:0005575	cellular_component	No
GO:0051179	localization	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 35	0.5

Transmembrane Domains

Domain #	Start	End	Length
1	10	32	22
2	59	81	22
3	91	110	19
4	131	153	22
5	163	185	22
6	197	219	22
7	255	277	22
8	290	312	22
9	359	381	22
10	402	424	22
11	428	450	22
12	457	476	19
13	496	518	22
14	564	586	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g7045.t1 MSDISPPLSQGVGYGVVIGVGLSFAAGMIFVTKALKSTVGEDNSNAETFIVANRRVSTGLVASAVVSSWLWSTAL LSAVLVAYQYGVSGPFWYGAGCSPMIVCFAYLGTVCKKRVPSAHTVLEIIKMRYGTVAHLSFTFLAVVNNLFNTI NMILGASVAITYLTGMHIMASTFLLPVGVVIYTLTGGIKATFLTDYIHTFIILILCCYLTTKALTSVEVKSIGGL YDLVIAAQPNHLVDGNYQGSLFTMTSQQGIFFGIILLVSNFGAVIMDTGYFTKAFAASPEGVVPGYVIGGLSYFS IPWALGTIMGMVALGLESTKAFPTYPRPMTSTEVTNGLALPYAAIAVAGKGGAVATLLMTFMAVTSTLSAQVIAV SSIVAFDGYRTYFNKNANNQEIIFWSRVGVIIFGLVAAGLTAMFHYVGIDMGWTLYMIGVITCPGIFPLILSILW RKQSRIAVIASAYLGLATGLAVWLGTAHHFYGAVTVSSTGQTLPCMYGTVASAVSPLLYSVLITLIAPEDFDWKS MSNNDLAIHSEGEVTEVTKERNETGQLSESSQRRWSRYALFWAVATFFGHWVLWPLPMYGARFIFSRGFFIAWVV LVGLFGEILGSEADNVPLDSSEDDGPLLRWKTDGRNKNGSGHLKRHGWLRGIYSLALEGRFPSDACEVIYGDSTT PAGSSEVQDLIHFQKLRDSLCAELDCQVCYALLLDPMTTPCGHTFCRKCVARVLNHTDLCPICRRKLGIPNDLQS EPINQPVARLVEYFFPDQISVRRETSAQDETGADYAKSLPLFVCTLSFPTMPTFLHVFEPRYRLMIQRVLASGNG KFGMVMHNRQGRVQPGQLHDAPFMQYGTLLMIERYELLPDGRSLVVATGVSRFKIVDSGMLDGYYVAKTERVDDI SLAEEERCESLETSTGGVNALSEGNEADPPLGSMPTQQLLLSAREYITNQRRYGAPWLHPRVMLAYGPIPTDAAR FPWWFASILPISEEEKYPLLAATSVRERLKLSAKWARQLEARDWSTRSSLYSVL*
Coding	>Pro_DTO377G3_2|g7045.t1 ATGTCCGACATATCTCCCCCGTTATCACAAGGTGTAGGGTATGGAGTCGTGATTGGTGTTGGGTTGTCATTTGCA GCAGGAATGATATTTGTCACCAAGGCATTGAAAAGTACAGTGGGCGAAGATAATTCGAATGCTGAAACATTTATT GTTGCCAATCGGAGAGTCAGCACGGGTTTAGTTGCCTCGGCAGTTGTATCTTCCTGGCTTTGGAGCACTGCATTG CTGAGTGCCGTATTGGTGGCCTATCAATACGGCGTAAGTGGCCCATTTTGGTATGGTGCTGGATGCTCACCTATG ATCGTCTGTTTTGCGTATCTCGGCACTGTCTGTAAAAAGCGTGTGCCCAGCGCGCACACTGTTCTGGAAATCATC AAGATGCGATATGGCACTGTCGCTCACTTAAGCTTCACCTTTCTGGCTGTGGTGAATAATCTCTTTAACACCATC AACATGATTTTAGGTGCTTCAGTCGCCATTACATATTTAACTGGGATGCACATCATGGCATCCACTTTCCTGCTG CCAGTTGGTGTGGTCATTTATACCCTCACTGGAGGTATCAAAGCAACGTTTCTAACTGATTATATTCACACTTTC ATTATTTTGATTCTGTGTTGTTATTTGACCACCAAAGCGTTGACCAGCGTGGAGGTCAAGTCGATTGGGGGTTTG TATGATCTTGTCATTGCAGCTCAGCCAAATCATCTCGTGGATGGAAATTACCAAGGCTCGCTTTTTACCATGACA TCTCAACAGGGAATTTTTTTTGGAATCATTCTTTTGGTGTCAAACTTCGGAGCTGTCATTATGGATACCGGATAC TTCACTAAGGCATTTGCTGCGTCCCCAGAAGGTGTCGTTCCTGGATACGTGATTGGGGGTTTATCTTATTTCAGT ATTCCTTGGGCTCTTGGAACTATTATGGGGATGGTTGCGTTGGGATTGGAGAGCACAAAGGCCTTCCCAACATAT CCGAGACCCATGACTAGTACTGAAGTCACGAATGGACTAGCTTTGCCTTACGCAGCCATCGCGGTAGCGGGCAAA GGTGGCGCAGTGGCTACTCTCCTGATGACTTTTATGGCTGTTACGTCTACACTGTCAGCACAGGTCATTGCTGTC TCTTCGATTGTGGCCTTTGATGGCTACCGCACCTACTTCAACAAGAATGCAAACAATCAAGAGATAATCTTCTGG AGTCGGGTGGGAGTGATTATATTCGGCCTTGTCGCGGCAGGCCTCACTGCAATGTTCCACTATGTTGGCATTGAC ATGGGCTGGACCCTTTACATGATTGGAGTGATCACCTGCCCCGGGATATTTCCCCTGATACTGTCGATTCTTTGG AGAAAGCAAAGCCGGATCGCGGTCATTGCGTCGGCGTATCTCGGTCTAGCCACGGGCCTCGCTGTCTGGCTCGGA ACAGCGCATCATTTCTATGGTGCCGTTACAGTCTCTTCAACTGGACAGACATTGCCATGCATGTACGGCACAGTG GCATCTGCAGTTAGCCCGTTACTATACTCCGTGTTGATTACATTGATTGCACCGGAAGACTTCGACTGGAAGTCG ATGAGCAATAACGACCTGGCTATCCATTCTGAGGGTGAAGTTACCGAGGTTACTAAAGAGAGAAATGAAACGGGC CAGCTTTCCGAGTCAAGCCAAAGGAGATGGTCACGATACGCGTTATTTTGGGCCGTTGCTACTTTCTTCGGCCAC TGGGTTCTCTGGCCACTTCCGATGTATGGTGCTAGGTTTATATTCAGCAGAGGATTCTTCATCGCCTGGGTTGTG CTGGTTGGCCTTTTTGGAGAAATACTGGGGTCGGAGGCAGACAACGTGCCTCTGGACTCGTCCGAGGATGACGGA CCGTTACTGCGCTGGAAAACCGACGGGCGGAATAAGAACGGAAGTGGGCATTTGAAGCGACATGGGTGGTTGAGG GGAATCTATAGCCTGGCACTGGAAGGCCGGTTCCCGTCTGATGCATGCGAAGTCATCTATGGAGATTCCACAACG CCAGCCGGAAGCTCAGAAGTTCAGGATCTCATTCACTTCCAAAAGCTGCGAGACAGTCTCTGCGCCGAGTTAGAC TGTCAGGTTTGCTATGCACTCCTTTTAGATCCGATGACGACGCCTTGTGGTCACACTTTTTGCCGAAAATGTGTC GCGCGGGTCTTAAACCATACAGATCTGTGTCCCATTTGTCGCCGAAAGCTAGGCATTCCGAATGATCTACAGTCA GAGCCCATAAACCAGCCTGTGGCACGGTTGGTCGAATACTTTTTCCCCGACCAGATCTCAGTCAGACGGGAGACC AGCGCCCAGGATGAGACAGGCGCGGATTACGCGAAGAGCTTGCCACTTTTTGTGTGCACGCTATCTTTCCCGACA ATGCCCACTTTTCTCCATGTCTTCGAGCCCAGATATCGACTTATGATTCAGCGGGTTCTCGCAAGTGGAAATGGA AAGTTCGGCATGGTCATGCACAACCGGCAAGGCCGGGTACAGCCAGGTCAATTACATGACGCACCGTTTATGCAA TACGGAACGCTATTGATGATCGAGCGATATGAGCTGCTTCCAGATGGTCGCAGTCTCGTGGTGGCTACAGGCGTA TCGCGGTTCAAGATCGTCGACTCGGGAATGCTGGATGGCTATTATGTTGCCAAAACAGAGCGCGTAGATGACATC TCGCTCGCAGAGGAGGAGCGATGTGAGTCGTTGGAGACCTCAACAGGCGGTGTAAATGCTCTGTCAGAAGGGAAT GAAGCTGATCCTCCGTTAGGCTCAATGCCAACTCAACAGCTACTCCTCTCAGCAAGAGAGTATATCACCAACCAG CGCAGATATGGGGCTCCTTGGCTGCACCCGCGCGTCATGCTAGCATATGGACCCATCCCTACAGATGCAGCCCGC TTCCCATGGTGGTTCGCAAGCATTTTGCCCATCTCCGAAGAAGAGAAATATCCCTTACTCGCCGCCACAAGTGTT CGAGAGAGACTGAAACTCTCAGCAAAATGGGCGAGACAACTTGAGGCTCGAGACTGGTCTACTCGCTCATCACTC TACTCTGTCTTATGA
Transcript	>Pro_DTO377G3_2|g7045.t1 ATGTCCGACATATCTCCCCCGTTATCACAAGGTGTAGGGTATGGAGTCGTGATTGGTGTTGGGTTGTCATTTGCA GCAGGAATGATATTTGTCACCAAGGCATTGAAAAGTACAGTGGGCGAAGATAATTCGAATGCTGAAACATTTATT GTTGCCAATCGGAGAGTCAGCACGGGTTTAGTTGCCTCGGCAGTTGTATCTTCCTGGCTTTGGAGCACTGCATTG CTGAGTGCCGTATTGGTGGCCTATCAATACGGCGTAAGTGGCCCATTTTGGTATGGTGCTGGATGCTCACCTATG ATCGTCTGTTTTGCGTATCTCGGCACTGTCTGTAAAAAGCGTGTGCCCAGCGCGCACACTGTTCTGGAAATCATC AAGATGCGATATGGCACTGTCGCTCACTTAAGCTTCACCTTTCTGGCTGTGGTGAATAATCTCTTTAACACCATC AACATGATTTTAGGTGCTTCAGTCGCCATTACATATTTAACTGGGATGCACATCATGGCATCCACTTTCCTGCTG CCAGTTGGTGTGGTCATTTATACCCTCACTGGAGGTATCAAAGCAACGTTTCTAACTGATTATATTCACACTTTC ATTATTTTGATTCTGTGTTGTTATTTGACCACCAAAGCGTTGACCAGCGTGGAGGTCAAGTCGATTGGGGGTTTG TATGATCTTGTCATTGCAGCTCAGCCAAATCATCTCGTGGATGGAAATTACCAAGGCTCGCTTTTTACCATGACA TCTCAACAGGGAATTTTTTTTGGAATCATTCTTTTGGTGTCAAACTTCGGAGCTGTCATTATGGATACCGGATAC TTCACTAAGGCATTTGCTGCGTCCCCAGAAGGTGTCGTTCCTGGATACGTGATTGGGGGTTTATCTTATTTCAGT ATTCCTTGGGCTCTTGGAACTATTATGGGGATGGTTGCGTTGGGATTGGAGAGCACAAAGGCCTTCCCAACATAT CCGAGACCCATGACTAGTACTGAAGTCACGAATGGACTAGCTTTGCCTTACGCAGCCATCGCGGTAGCGGGCAAA GGTGGCGCAGTGGCTACTCTCCTGATGACTTTTATGGCTGTTACGTCTACACTGTCAGCACAGGTCATTGCTGTC TCTTCGATTGTGGCCTTTGATGGCTACCGCACCTACTTCAACAAGAATGCAAACAATCAAGAGATAATCTTCTGG AGTCGGGTGGGAGTGATTATATTCGGCCTTGTCGCGGCAGGCCTCACTGCAATGTTCCACTATGTTGGCATTGAC ATGGGCTGGACCCTTTACATGATTGGAGTGATCACCTGCCCCGGGATATTTCCCCTGATACTGTCGATTCTTTGG AGAAAGCAAAGCCGGATCGCGGTCATTGCGTCGGCGTATCTCGGTCTAGCCACGGGCCTCGCTGTCTGGCTCGGA ACAGCGCATCATTTCTATGGTGCCGTTACAGTCTCTTCAACTGGACAGACATTGCCATGCATGTACGGCACAGTG GCATCTGCAGTTAGCCCGTTACTATACTCCGTGTTGATTACATTGATTGCACCGGAAGACTTCGACTGGAAGTCG ATGAGCAATAACGACCTGGCTATCCATTCTGAGGGTGAAGTTACCGAGGTTACTAAAGAGAGAAATGAAACGGGC CAGCTTTCCGAGTCAAGCCAAAGGAGATGGTCACGATACGCGTTATTTTGGGCCGTTGCTACTTTCTTCGGCCAC TGGGTTCTCTGGCCACTTCCGATGTATGGTGCTAGGTTTATATTCAGCAGAGGATTCTTCATCGCCTGGGTTGTG CTGGTTGGCCTTTTTGGAGAAATACTGGGGTCGGAGGCAGACAACGTGCCTCTGGACTCGTCCGAGGATGACGGA CCGTTACTGCGCTGGAAAACCGACGGGCGGAATAAGAACGGAAGTGGGCATTTGAAGCGACATGGGTGGTTGAGG GGAATCTATAGCCTGGCACTGGAAGGCCGGTTCCCGTCTGATGCATGCGAAGTCATCTATGGAGATTCCACAACG CCAGCCGGAAGCTCAGAAGTTCAGGATCTCATTCACTTCCAAAAGCTGCGAGACAGTCTCTGCGCCGAGTTAGAC TGTCAGGTTTGCTATGCACTCCTTTTAGATCCGATGACGACGCCTTGTGGTCACACTTTTTGCCGAAAATGTGTC GCGCGGGTCTTAAACCATACAGATCTGTGTCCCATTTGTCGCCGAAAGCTAGGCATTCCGAATGATCTACAGTCA GAGCCCATAAACCAGCCTGTGGCACGGTTGGTCGAATACTTTTTCCCCGACCAGATCTCAGTCAGACGGGAGACC AGCGCCCAGGATGAGACAGGCGCGGATTACGCGAAGAGCTTGCCACTTTTTGTGTGCACGCTATCTTTCCCGACA ATGCCCACTTTTCTCCATGTCTTCGAGCCCAGATATCGACTTATGATTCAGCGGGTTCTCGCAAGTGGAAATGGA AAGTTCGGCATGGTCATGCACAACCGGCAAGGCCGGGTACAGCCAGGTCAATTACATGACGCACCGTTTATGCAA TACGGAACGCTATTGATGATCGAGCGATATGAGCTGCTTCCAGATGGTCGCAGTCTCGTGGTGGCTACAGGCGTA TCGCGGTTCAAGATCGTCGACTCGGGAATGCTGGATGGCTATTATGTTGCCAAAACAGAGCGCGTAGATGACATC TCGCTCGCAGAGGAGGAGCGATGTGAGTCGTTGGAGACCTCAACAGGCGGTGTAAATGCTCTGTCAGAAGGGAAT GAAGCTGATCCTCCGTTAGGCTCAATGCCAACTCAACAGCTACTCCTCTCAGCAAGAGAGTATATCACCAACCAG CGCAGATATGGGGCTCCTTGGCTGCACCCGCGCGTCATGCTAGCATATGGACCCATCCCTACAGATGCAGCCCGC TTCCCATGGTGGTTCGCAAGCATTTTGCCCATCTCCGAAGAAGAGAAATATCCCTTACTCGCCGCCACAAGTGTT CGAGAGAGACTGAAACTCTCAGCAAAATGGGCGAGACAACTTGAGGCTCGAGACTGGTCTACTCGCTCATCACTC TACTCTGTCTTATGA
Gene	>Pro_DTO377G3_2|g7045.t1 ATGTCCGACATATCTCCCCCGTTATCACAAGGTGTAGGGTATGGAGTCGTGATTGGTGTTGGGTTGTCATTTGCA GCAGGTAGGACGTAAATACACAACTCTTCTTATGACTATGCTAAGAATAATGAAGGAATGATATTTGTCACCAAG GCATTGAAAAGTACAGTGGGCGAAGATAATTCGAATGCTGAAACGTATGTTTTTCCCCAAGCTTCTCATCTGACT CCTTTTTAATCCCAACTAGATTTATTGTTGCCAATCGGAGAGTCAGCACGGGTTTAGTTGCCTCGGCAGTTGTAT CTGTATGTGAACAAATGCTTAACAATATTCAGTGCTAACCTACAATAGTCCTGGCTTTGGAGCACTGCATTGCTG AGTGCCGTATTGGTGGCCTATCAATACGGCGTAAGTGGCCCATTTTGGTATGGTGCTGGATGCTCACCTATGATC GTCTGTTTTGCGTATCTCGGCACTGTCTGTAAAAAGCGTGTGCCCAGCGCGCACACTGTTCTGGAAATCATCAAG ATGCGATATGGTGAGGACTTTACGTGTCTGTCAGTGAAACATGAAAACTAACAATTTCAAGGCACTGTCGCTCAC TTAAGCTTCACCTTTCTGGCTGTGGTGAATAATCTCTTTAACACCATCAACATGATTTTAGGTGCTTCAGTCGCC ATTACATATTTGTAAGTCCGGTAACCGCGCTCGAAAACACTTGTGGTCAATCGGCTTACCATGAAAGAACTGGGA TGCACATCATGGCATCCACTTTCCTGCTGCCAGTTGGTGTGGTCATTTATACCCTCACTGGAGGTATCAAAGCAA CGTATGTCAGATTATTTTTCAAAATATGTCCACAGCACTAATAGGGTTTGCAGGTTTCTAACTGATTATATTCAC ACTTTCATTATTTTGATTCTGTGTTGTTATTTGACCACCAAAGCGTTGACCAGCGTGGAGGTCAAGTCGATTGGG GGTTTGTATGATCTTGTCATTGCAGCTCAGCCAAATCATCTCGTGGATGGAAATTACCAAGGCTCGCTTTTTACC ATGACATCTCAACAGGGAATTTTTTTTGGAATCATTCTTTTGGTGTCAAACTTCGGAGCTGTCATTGTAAGTGCC TCCCCGAATTACTGACGGCTTGGTGCTAATTGGGAATAGATGGATACCGGATACTTCACTAAGGCATTTGCTGCG TCCCCAGAAGGTGTCGTTCCTGGATACGTGATTGGGGGTTTATCTTATTTCAGTATTCCTTGGGCTCTTGGAACT ATTATGGGGATGGTTGCGTTGGGATTGGAGAGCACAAAGGCCTTCCCAACATATCCGAGAGTAAGTCCAGGCCAT CGATTCTCGATATTTGATCTTGAAGCTAAGATATTTCGAGCCCATGACTAGTACTGAAGTCACGAATGGACTAGC TTTGCCTTACGCAGCCATCGCGGTAGCGGGCAAAGGTGGCGCAGTGGCTACTCTCCTGATGACTTTTATGGCTGT TACGTCTACACTGTCAGCACAGGTCATTGCTGTCTCTTCGATTGTGGCCTTTGATGGCTACCGCACCTACTTCAA CAAGAATGCAAACAATCAAGAGATAATCTTCTGGAGTCGGGTGGGAGTGATTATATTCGGCCTTGTCGCGGCAGG CCTCACTGCAATGTTCCACTATGTTGGCATTGACATGGGCTGGACCCTTTACATGATTGGTAAGCTCAGGTACTT ATATCAAGGATATACTCGATGTTTCTAACATAACTCGAAGGAGTGATCACCTGCCCCGGGATATTTCCCCTGATA CTGTCGATTCTTTGGAGAAAGCAAAGCCGGATCGCGGTCATTGCGTCGGCGTATCTCGGTCTAGCCACGGGCCTC GCTGTCTGGCTCGGAACAGCGCATCATTTCTATGGTGCCGTTACAGTCTCTTCAACTGGACAGACATTGCCATGC ATGTACGGCACAGTGGCATCTGCAGTTAGCCCGTTACTATACTCCGTGTTGATTACATTGATTGCACCGGAAGAC TTCGACTGGAAGTCGATGAGCAATAACGACCTGGCTATCCATTCTGAGGGTGAAGTTACCGAGGTTACTAAAGAG AGAAATGAAACGGGCCAGCTTTCCGAGTCAAGCCAAAGGAGATGGTCACGATACGCGTTATTTTGGGCCGTTGCT ACTTTCTTCGGCCACTGGGTTCTCTGGCCACTTCCGATGTATGGTGCTAGGTTTATATTCAGCAGAGGAGTAAGT GCACTATATTTTCTCAAGGGTGGACAATGTCACTGACAAGATTTAGTTCTTCATCGCCTGGGTTGTGGTTGCTGA AATTTGGCTCTGGATCACTTTGCTGACGGTTGGATTATATCCTTTGTGGGATGGACGCCGTCGGATTCTTTTCAT CGCGCGGAGACTTGTTGGGCGTTTGGAAAATGCATAATTATTTGGTTGCCGATTGAGTGCTCACTGCTTAGCAGC ATCATCAGTTTTATTCCGCATAATTAGTATAAGAATAAGTCGGATGCATTTACAGCCTATATCATTGAGAATGAC ATCCATGGATGGTTGCAGAGCGAAGCGACTGATGATCACATGATGGCCCATTAGAACGCTATTATTTCAGCCCTG GGAGAAACTTGGCCACGTGACACGTACGTAAGACCTTTTGATTTATACTTGCTTTGCTTCGTTTCGTTACGCAAT TAATATTATTTCTTTGTATAACCACTACTATAAACGATGTACTGCGACACCGGACCTCGGGATGGTCACTGATCC GATTATCTAAAGTTGACCCACACCTGAGCACCTGCAGATAGCGGATCCCCCACCCCCCGAGCTTCATCATTTATC CTTCTACGTTTCCCTCTTATTCACTGCATTTGTACCCGTGGACTGCAGTGTAATGGAAGATGCAGCCGAGTCCCT GAGCCTGACACAAATGACCGACGCTGAACCTATCCCGACCGTAATGGAGAGCCCGGAGGACTCAAGCTCAGATGT TTCAAGCTCGGAAGAACATACACCTAGCGATACGGCAGATCTACCTCATATCGTGATCCAATTGATCCAGTGCCA ACATTGCTCCCGCCCTTTCCGAACTCCGCTCCGCCTACCATGCGGGAATTCGATCTGTCGGGAATGTTTGCCCGC CCTTCGGCCCCGGACAGGTATTACGTACCCCGTGACTGAGGGGAGGAATCAGGAATTCACATGCCTTTGGAAAGG AAATAAGACGTGTGGTGGGGGCCATTGTGTTGCAGATTGTGGCGCTGATGTGCTGCTTGGGAAGCTGGTTGGCCT TTTTGGAGAAATACTGGGGTCGGAGGCAGACAACGTGCCTCTGGACTCGTCCGAGGATGACGGACCGTTACTGCG CTGGAAAACCGACGGGCGGAATAAGAACGGAAGTGGGCATTTGAAGCGACATGGGTGGTTGAGGGGAATCTATAG CCTGGCACTGGAAGGCCGGTTCCCGTCTGATGCATGCGAAGTCATCTATGGAGATTCCACAACGCCAGCCGGAAG CTCAGAAGTTCAGGATCTCATTCACTTCCAAAAGCTGCGAGACAGTCTCTGCGCCGAGTTAGACTGTCAGGTTTG CTATGCACTCCTTTTAGATCCGATGACGACGCCTTGTGGTCACACTTTTTGCCGAAAATGTGTCGCGCGGGTCTT AAACCATACAGATCTGTGTCCCATTTGTCGCCGAAAGCTAGGCATTCCGAATGATCTACAGTCAGAGCCCATAAA CCAGCCTGTGGCACGGTTGGTCGAATACTTTTTCCCCGACCAGATCTCAGTCAGACGGGAGACCAGCGCCCAGGA TGAGACAGGCGCGGATTACGCGAAGAGCTTGCCACTTTTTGTGTGCACGCTATCTTTCCCGACAATGCCCACTTT TCTCCATGTCTTCGAGCCCAGATATCGACTTATGATTCAGCGGGTTCTCGCAAGTGGAAATGGAAAGTTCGGCAT GGTCATGCACAACCGGCAAGGCCGGGTACAGCCAGGTCAATTACATGACGCACCGTTTATGCAATACGGAACGCT ATTGATGATCGAGCGATATGAGCTGCTTCCAGATGGTCGCAGTCTCGTGGTGGCTACAGGCGTATCGCGGTTCAA GATCGTCGACTCGGGAATGCTGGATGGCTATTATGTTGCCAAAACAGAGCGCGTAGATGACATCTCGCTCGCAGA GGAGGAGCGATGTGAGTCGTTGGAGACCTCAACAGGCGGTGTAAATGCTCTGTCAGAAGGGAATGAAGCTGATCC TCCGTTAGGCTCAATGCCAACTCAACAGCTACTCCTCTCAGCAAGAGAGTATATCACCAACCAGCGCAGATATGG GGCTCCTTGGCTGCACCCGCGCGTCATGCTAGCATATGGACCCATCCCTACAGATGCAGCCCGCTTCCCATGGTG GTTCGCAAGCATTTTGCCCATCTCCGAAGAAGAGAAATATCCCTTACTCGCCGCCACAAGTGTTCGAGAGAGACT GAAACTCTCAGCAAAATGGGCGAGACAACTTGAGGCTCGAGACTGGTAGGTTCAACATCTCTTCTCCCCATTAGA TGCTATGCTGATATTTCCGATTAGGTCTACTCGCTCATCACTCTACTCTGTCTTATGA