Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g693.t1
Gene name
Location	scaffold_01:1799312..1803788
Strand	-
Gene length (bp)	4476
Transcript length (bp)	3324
Coding sequence length (bp)	3324
Protein length (aa)	1108

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF13561	adh_short_C2	Enoyl-(Acyl carrier protein) reductase	1.6E-41	10	231
PF00106	adh_short	short chain dehydrogenase	1.0E-41	5	210
PF00664	ABC_membrane	ABC transporter transmembrane region	7.0E-34	535	809
PF00005	ABC_tran	ABC transporter	1.9E-32	871	1020

GO

GO Term	Description	Terminal node
GO:0055085	transmembrane transport	Yes
GO:0016021	integral component of membrane	Yes
GO:0005524	ATP binding	Yes
GO:0140359	ABC-type transporter activity	Yes
GO:0097367	carbohydrate derivative binding	No
GO:0051234	establishment of localization	No
GO:0022857	transmembrane transporter activity	No
GO:0030554	adenyl nucleotide binding	No
GO:0005575	cellular_component	No
GO:0015399	primary active transmembrane transporter activity	No
GO:0140657	ATP-dependent activity	No
GO:0022804	active transmembrane transporter activity	No
GO:0017076	purine nucleotide binding	No
GO:0008150	biological_process	No
GO:0006810	transport	No
GO:0043167	ion binding	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0032553	ribonucleotide binding	No
GO:0000166	nucleotide binding	No
GO:1901265	nucleoside phosphate binding	No
GO:0005488	binding	No
GO:0036094	small molecule binding	No
GO:0003674	molecular_function	No
GO:0097159	organic cyclic compound binding	No
GO:0042626	ATPase-coupled transmembrane transporter activity	No
GO:0032555	purine ribonucleotide binding	No
GO:0051179	localization	No
GO:0031224	intrinsic component of membrane	No
GO:0005215	transporter activity	No
GO:0110165	cellular anatomical entity	No
GO:1901363	heterocyclic compound binding	No
GO:0043168	anion binding	No
GO:0009987	cellular process	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 22	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	246	268	22
2	311	333	22
3	343	365	22
4	378	400	22
5	425	447	22
6	651	673	22
7	677	699	22
8	764	786	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g693.t1 MFPGVAVITGAGGTGIGAATAKAFAAAGCERIAITDLNEKSLQTTAKAIASTYPKTQLLVKAGNVADDQFADSFI DAVVQQFGRVDYAVNCAGVLGKSLRSAETSLEEFDRVNNINYRGCWLSSRAELRQMVSQSELPSHDPNRPGQRGA VVNVASQLGIVSRPGAPAYCASKSAVIGMTRADGIDYSKNGIRVNCVCPGVIETPLIMENPEIRAAITPAAEIAP MKRMAMDSAIVAQELLQYLRFGYPPILLGFIFIVFLVHSSQVARNADRNIKVQYGPNGKPLPRRTRMMMAVARDL PAELARNRSKGWFVWLDLFVLATYIAEAAIHMTHAIVSKSEQWWCGQAVVFFVVGAFFTHTVIFISLLENRGPSI AQFVPWLSAIPFEIAILSTSISIYSHIHHEPTIEDPFGGRLRTKITFWEALEISAGSVRIFVLTLLVASYIFKSA RKHCAFKEAEDADAGETTSLLDSRGNANSDDGDALTDGQQTPEVEAWVRPLTTPSTNWMEYLSGYSLFFPYLWPY KSLRLQIVVVMCFAILIVQRAVNILVPYQVGVIADSLSTSDGNLKVPWMPICLYIIYRWLQGSQGFLESVRSNLW ISVSQYAYMELSTASFEHVHNLGLDFHLGKKMGEVLSALTKGNSINTFLEQVTFQVLPMFIDLTIAIGYFLIVFD VYYALAVAVMTFFYLYSTIKIASWRANMRRQMVNASRQEDAVKNDSLVSYETVKYFNAEEYEFNRYRGAVSDYLR AEWHSLFAQNLMNICQNVIFMFGLLITCFICAYQVARGQRPVGQFVTLLTYMAQLQAPLNIFGTFYRYIQSALIN AERLLELFRVQPSVVDAPSATPLAVCHGRITFNEIKFSYDTRRPALNGLTFDCKPGTTTALVGESGGGKSTIFRL LYRFYNPSSGNLLIDGYDTQTLTIDSVRRHIGVVPQDTVLFNETIMYNLKYANQNATDEEVYEACRAASVHDKIM AFPDGYETKVGDRGLRLSGGEKQRVAIARTIIKKPQIILLDEATAALDSETEQNIQEALAILSRGRTVLVIAHRL STITTADNIVVLHEGRVAETGTHEQLLAANGRYKAMWQKQIRAQTESVGLNALSGKI*
Coding	>Pro_DTO377G3_2|g693.t1 ATGTTTCCTGGCGTGGCAGTCATTACTGGTGCTGGTGGAACAGGAATCGGCGCTGCAACAGCCAAAGCCTTTGCC GCAGCAGGATGTGAGAGAATTGCTATCACAGATCTAAACGAAAAGTCTTTGCAGACAACCGCAAAAGCCATTGCT TCTACATACCCCAAGACTCAACTCCTAGTGAAAGCTGGGAATGTGGCAGATGACCAGTTCGCAGACTCGTTTATT GACGCAGTCGTACAACAATTCGGACGAGTCGACTATGCTGTCAACTGTGCAGGTGTCCTTGGGAAGTCATTGCGC TCAGCGGAAACGAGCCTCGAAGAATTTGACCGGGTCAACAATATCAACTACCGAGGCTGCTGGCTGTCTTCTCGA GCAGAGCTTAGACAGATGGTGTCTCAAAGTGAACTCCCAAGTCACGACCCTAACCGTCCTGGCCAGCGGGGCGCA GTTGTGAACGTTGCTAGTCAGTTGGGAATCGTTAGCCGTCCAGGTGCTCCTGCGTATTGTGCATCAAAATCCGCG GTCATTGGAATGACTCGGGCAGATGGTATCGATTATTCCAAGAATGGGATTCGAGTCAACTGTGTCTGTCCAGGT GTCATTGAAACACCACTCATCATGGAGAATCCCGAGATTCGCGCGGCCATCACTCCAGCAGCGGAGATAGCCCCT ATGAAGAGAATGGCCATGGATTCGGCTATCGTTGCCCAAGAATTGCTTCAATATCTTCGCTTTGGATACCCTCCG ATTTTGCTAGGGTTTATCTTTATCGTCTTTTTGGTCCATTCCTCTCAGGTGGCCAGAAATGCTGATCGCAACATT AAAGTCCAGTATGGCCCCAATGGGAAACCACTGCCTAGGCGAACCCGAATGATGATGGCGGTGGCCAGGGACTTG CCCGCGGAGCTTGCGCGGAATAGATCCAAGGGCTGGTTTGTTTGGCTGGATCTGTTTGTGCTGGCAACCTATATT GCTGAGGCAGCAATTCATATGACCCATGCCATAGTTTCAAAGTCAGAGCAGTGGTGGTGTGGTCAAGCGGTAGTG TTCTTTGTCGTCGGGGCTTTCTTCACTCATACCGTTATCTTCATCTCTTTACTCGAGAACCGTGGACCGTCAATC GCGCAATTCGTCCCATGGCTCTCGGCCATTCCCTTCGAGATAGCCATTCTCTCAACTTCAATCTCAATCTATTCC CACATCCACCATGAACCTACAATCGAAGATCCATTCGGTGGAAGATTGCGTACAAAGATCACATTTTGGGAGGCA TTGGAGATTTCCGCAGGTTCAGTGCGGATTTTTGTTCTCACACTGCTGGTCGCGTCCTACATTTTCAAATCTGCC CGCAAACATTGCGCATTCAAGGAGGCTGAGGATGCCGATGCCGGAGAGACGACTAGCCTGCTAGATTCAAGAGGC AATGCCAACTCGGATGATGGTGATGCCTTGACCGATGGTCAACAGACCCCGGAAGTAGAAGCATGGGTGCGGCCT TTGACGACCCCTTCCACCAACTGGATGGAATATCTGAGTGGCTATTCCCTATTCTTTCCATATCTGTGGCCTTAC AAGTCTCTCCGGTTGCAAATTGTCGTCGTCATGTGCTTTGCTATATTGATTGTGCAGCGAGCGGTAAATATCCTA GTCCCATATCAAGTGGGAGTGATCGCAGACTCATTGTCCACCAGCGATGGAAATCTGAAAGTGCCTTGGATGCCC ATCTGTCTGTATATCATCTACCGTTGGCTTCAAGGTAGTCAAGGTTTCCTTGAGTCGGTTCGCTCGAATCTGTGG ATCTCAGTGAGCCAGTATGCATACATGGAGTTGTCAACCGCTTCATTTGAGCATGTTCATAACCTAGGACTGGAC TTTCACCTGGGTAAAAAGATGGGCGAGGTTCTCTCTGCCCTCACCAAAGGCAACTCAATCAACACTTTTCTTGAG CAAGTGACATTTCAAGTGTTGCCGATGTTCATTGATTTGACCATCGCCATTGGTTATTTTCTAATCGTATTTGAC GTGTACTACGCGTTGGCTGTTGCTGTCATGACATTCTTCTACCTCTATTCAACCATCAAGATTGCCTCTTGGAGG GCCAATATGCGACGTCAAATGGTGAACGCTTCCAGACAGGAAGACGCTGTCAAGAATGATTCCCTTGTGTCCTAC GAAACTGTCAAATACTTCAACGCAGAGGAATACGAGTTCAATCGCTATCGAGGAGCGGTCTCAGACTACCTCCGT GCGGAATGGCATTCCCTATTCGCACAGAATCTGATGAATATTTGCCAGAATGTCATTTTCATGTTTGGCCTTCTC ATCACCTGTTTTATTTGTGCCTACCAAGTTGCTCGTGGTCAACGTCCAGTCGGCCAGTTCGTGACGCTCCTTACC TACATGGCCCAACTGCAAGCCCCATTGAACATCTTCGGAACCTTCTACCGGTACATTCAATCAGCGTTGATCAAC GCAGAGCGTCTACTCGAGCTTTTCCGCGTCCAGCCATCGGTAGTGGATGCACCGTCTGCAACACCGCTAGCAGTC TGTCACGGCCGAATCACATTTAACGAGATCAAATTCTCGTATGACACCCGACGACCTGCTCTCAACGGATTGACC TTTGACTGTAAACCGGGTACAACTACAGCTCTGGTAGGAGAATCAGGTGGCGGGAAATCGACAATCTTCCGCTTG CTCTATAGGTTCTACAATCCGAGCAGCGGAAATCTTCTTATTGACGGATACGATACGCAGACCTTGACAATTGAT TCGGTACGCAGACACATTGGCGTCGTCCCACAAGACACCGTTCTCTTCAACGAAACAATCATGTACAACCTCAAA TATGCCAACCAAAACGCCACCGACGAGGAAGTCTACGAGGCCTGCCGTGCAGCCAGTGTACACGACAAGATCATG GCGTTCCCCGACGGTTACGAAACCAAAGTGGGAGATCGTGGATTACGACTAAGTGGTGGTGAGAAACAGCGCGTC GCCATTGCCCGAACCATTATCAAGAAACCTCAGATCATCCTGCTTGATGAGGCAACGGCCGCATTAGATTCCGAG ACGGAGCAGAACATTCAAGAAGCACTAGCCATCCTGTCACGTGGGCGCACAGTGCTAGTAATTGCCCATCGGCTG AGCACCATCACCACTGCTGATAACATTGTTGTATTGCACGAAGGTCGGGTTGCAGAGACTGGGACCCATGAGCAA CTTCTGGCTGCTAATGGTCGATATAAAGCTATGTGGCAGAAGCAGATTCGTGCACAGACCGAATCTGTGGGCTTG AATGCCTTGTCAGGCAAGATATAG
Transcript	>Pro_DTO377G3_2|g693.t1 ATGTTTCCTGGCGTGGCAGTCATTACTGGTGCTGGTGGAACAGGAATCGGCGCTGCAACAGCCAAAGCCTTTGCC GCAGCAGGATGTGAGAGAATTGCTATCACAGATCTAAACGAAAAGTCTTTGCAGACAACCGCAAAAGCCATTGCT TCTACATACCCCAAGACTCAACTCCTAGTGAAAGCTGGGAATGTGGCAGATGACCAGTTCGCAGACTCGTTTATT GACGCAGTCGTACAACAATTCGGACGAGTCGACTATGCTGTCAACTGTGCAGGTGTCCTTGGGAAGTCATTGCGC TCAGCGGAAACGAGCCTCGAAGAATTTGACCGGGTCAACAATATCAACTACCGAGGCTGCTGGCTGTCTTCTCGA GCAGAGCTTAGACAGATGGTGTCTCAAAGTGAACTCCCAAGTCACGACCCTAACCGTCCTGGCCAGCGGGGCGCA GTTGTGAACGTTGCTAGTCAGTTGGGAATCGTTAGCCGTCCAGGTGCTCCTGCGTATTGTGCATCAAAATCCGCG GTCATTGGAATGACTCGGGCAGATGGTATCGATTATTCCAAGAATGGGATTCGAGTCAACTGTGTCTGTCCAGGT GTCATTGAAACACCACTCATCATGGAGAATCCCGAGATTCGCGCGGCCATCACTCCAGCAGCGGAGATAGCCCCT ATGAAGAGAATGGCCATGGATTCGGCTATCGTTGCCCAAGAATTGCTTCAATATCTTCGCTTTGGATACCCTCCG ATTTTGCTAGGGTTTATCTTTATCGTCTTTTTGGTCCATTCCTCTCAGGTGGCCAGAAATGCTGATCGCAACATT AAAGTCCAGTATGGCCCCAATGGGAAACCACTGCCTAGGCGAACCCGAATGATGATGGCGGTGGCCAGGGACTTG CCCGCGGAGCTTGCGCGGAATAGATCCAAGGGCTGGTTTGTTTGGCTGGATCTGTTTGTGCTGGCAACCTATATT GCTGAGGCAGCAATTCATATGACCCATGCCATAGTTTCAAAGTCAGAGCAGTGGTGGTGTGGTCAAGCGGTAGTG TTCTTTGTCGTCGGGGCTTTCTTCACTCATACCGTTATCTTCATCTCTTTACTCGAGAACCGTGGACCGTCAATC GCGCAATTCGTCCCATGGCTCTCGGCCATTCCCTTCGAGATAGCCATTCTCTCAACTTCAATCTCAATCTATTCC CACATCCACCATGAACCTACAATCGAAGATCCATTCGGTGGAAGATTGCGTACAAAGATCACATTTTGGGAGGCA TTGGAGATTTCCGCAGGTTCAGTGCGGATTTTTGTTCTCACACTGCTGGTCGCGTCCTACATTTTCAAATCTGCC CGCAAACATTGCGCATTCAAGGAGGCTGAGGATGCCGATGCCGGAGAGACGACTAGCCTGCTAGATTCAAGAGGC AATGCCAACTCGGATGATGGTGATGCCTTGACCGATGGTCAACAGACCCCGGAAGTAGAAGCATGGGTGCGGCCT TTGACGACCCCTTCCACCAACTGGATGGAATATCTGAGTGGCTATTCCCTATTCTTTCCATATCTGTGGCCTTAC AAGTCTCTCCGGTTGCAAATTGTCGTCGTCATGTGCTTTGCTATATTGATTGTGCAGCGAGCGGTAAATATCCTA GTCCCATATCAAGTGGGAGTGATCGCAGACTCATTGTCCACCAGCGATGGAAATCTGAAAGTGCCTTGGATGCCC ATCTGTCTGTATATCATCTACCGTTGGCTTCAAGGTAGTCAAGGTTTCCTTGAGTCGGTTCGCTCGAATCTGTGG ATCTCAGTGAGCCAGTATGCATACATGGAGTTGTCAACCGCTTCATTTGAGCATGTTCATAACCTAGGACTGGAC TTTCACCTGGGTAAAAAGATGGGCGAGGTTCTCTCTGCCCTCACCAAAGGCAACTCAATCAACACTTTTCTTGAG CAAGTGACATTTCAAGTGTTGCCGATGTTCATTGATTTGACCATCGCCATTGGTTATTTTCTAATCGTATTTGAC GTGTACTACGCGTTGGCTGTTGCTGTCATGACATTCTTCTACCTCTATTCAACCATCAAGATTGCCTCTTGGAGG GCCAATATGCGACGTCAAATGGTGAACGCTTCCAGACAGGAAGACGCTGTCAAGAATGATTCCCTTGTGTCCTAC GAAACTGTCAAATACTTCAACGCAGAGGAATACGAGTTCAATCGCTATCGAGGAGCGGTCTCAGACTACCTCCGT GCGGAATGGCATTCCCTATTCGCACAGAATCTGATGAATATTTGCCAGAATGTCATTTTCATGTTTGGCCTTCTC ATCACCTGTTTTATTTGTGCCTACCAAGTTGCTCGTGGTCAACGTCCAGTCGGCCAGTTCGTGACGCTCCTTACC TACATGGCCCAACTGCAAGCCCCATTGAACATCTTCGGAACCTTCTACCGGTACATTCAATCAGCGTTGATCAAC GCAGAGCGTCTACTCGAGCTTTTCCGCGTCCAGCCATCGGTAGTGGATGCACCGTCTGCAACACCGCTAGCAGTC TGTCACGGCCGAATCACATTTAACGAGATCAAATTCTCGTATGACACCCGACGACCTGCTCTCAACGGATTGACC TTTGACTGTAAACCGGGTACAACTACAGCTCTGGTAGGAGAATCAGGTGGCGGGAAATCGACAATCTTCCGCTTG CTCTATAGGTTCTACAATCCGAGCAGCGGAAATCTTCTTATTGACGGATACGATACGCAGACCTTGACAATTGAT TCGGTACGCAGACACATTGGCGTCGTCCCACAAGACACCGTTCTCTTCAACGAAACAATCATGTACAACCTCAAA TATGCCAACCAAAACGCCACCGACGAGGAAGTCTACGAGGCCTGCCGTGCAGCCAGTGTACACGACAAGATCATG GCGTTCCCCGACGGTTACGAAACCAAAGTGGGAGATCGTGGATTACGACTAAGTGGTGGTGAGAAACAGCGCGTC GCCATTGCCCGAACCATTATCAAGAAACCTCAGATCATCCTGCTTGATGAGGCAACGGCCGCATTAGATTCCGAG ACGGAGCAGAACATTCAAGAAGCACTAGCCATCCTGTCACGTGGGCGCACAGTGCTAGTAATTGCCCATCGGCTG AGCACCATCACCACTGCTGATAACATTGTTGTATTGCACGAAGGTCGGGTTGCAGAGACTGGGACCCATGAGCAA CTTCTGGCTGCTAATGGTCGATATAAAGCTATGTGGCAGAAGCAGATTCGTGCACAGACCGAATCTGTGGGCTTG AATGCCTTGTCAGGCAAGATATAG
Gene	>Pro_DTO377G3_2|g693.t1 ATGTTTCCTGGCGTGGCAGTCATTACTGGTGCTGGTGGAACAGGTACGTAGCATAGCCGACCGTTGTGGATATAT CACCAACATGATCTAGGAATCGGCGCTGCAACAGCCAAAGCCTTTGCCGCAGCAGGATGTGAGAGAATTGCTATC ACAGATCTAAACGAAAAGTCTTTGCAGACAACCGCAAAAGCCATTGCTTCTACATACCCCAAGACTCAACTCCTA GTGAAAGCTGGGAATGTGGCAGATGACCAGTTCGCAGACTCGTTTATTGACGCAGTCGTACAACAATTCGGACGA GTCGACTATGCTGTCAACTGTGCAGGTGTCCTTGGGAAGTCATTGCGCTCAGCGGAAACGAGCCTCGAAGAATTT GACCGGGTCAACAATATCAACTACCGAGGCTGCTGGCTGTCTTCTCGAGCAGAGCTTAGACAGATGGTGTCTCAA AGTGAACTCCCAAGTCACGACCCTAACCGTCCTGGCCAGCGGGGCGCAGTTGTGAACGTTGCTAGTCAGTTGGGA ATCGTTAGCCGTCCAGGTGCTCGTAAGTTCTGCGCTGCTGTCCATTTAAACCCACGATTGACAAGTGTTCTAGCT GCGTATTGTGCATCAAAATCCGCGGTCATTGGAATGACTCGGGCAGATGGTATCGATTATTCCAAGAATGGGATT CGAGTCAACTGTGTCTGTCCAGGTGTCATTGAAACACCACTCATCATGGAGAATCCCGAGATTCGCGCGGCCATC ACTCCAGCAGCGGAGATAGCCCCTATGAAGAGAATGGGTCAGCCAGCAGAGGTCGCCGATGCAATCCTTTTCTTA TGCTCCACGCAGGCCTCTTTTGTACAGGGTCATGCTATGGTAGTTGATGGTGGATATATTACTGTATAGTTTACC ATGAACAAGTAATGATGAGATATATTAGCCGAGAAATTAAATGAACAATTTCAATATCCCTATGCAATGCATATA TACAGTCTGCATTCCAACGGGCAACATAGGGAGCAAACCTAGCTGGATGGCCACCAATGCTCTCATGGTATCGGC GATGGGAGGCTGAGTATGAGGTCCAGCCACCTTAACTTGACCTTCAGCGGCCTACCCGGATCGTCCCAGGGAGAT TGACGTACGCAGCACCCAGCCGCTCAGCTCCTGCTCAATGGGCGAATCAGGGCACTTAAATAGGCAAATGGTCAG GTGATAGTCAGGTGATGCTGGTGTCGGTGAGCGAACCTTGAACGGCAAAGTATGTGAATTATGTAAGCATCCTGC TCAGCCCTTGATAAAAGAGCGGTAAGAGACAACGACCAAAAAGGAAGGAGAAGGTCCAGAAGGGCGGAAATCCAG TACATATATATTCGGTACGAGGTCAAGTACATACCCTGTACTCTATACTTGTCTATATACTAGATAATAGCGTCT GTCTGGAGTATACACAAGTCACTGACCCCGATCTTCAGGTCAGACATGCATCGATGGGTAACACAATCTTGGAAG TAAAGATTACTAGCCAATACAGTGGCGTTACTAGTGTCCCTCCGAGCTCCACTGATTGACAGCACCGTCGCAACT AAAATGTGAGCGCACGACAGCTCAATTGTGAACTTTCAGCTTGCGATCTCGCAGCCAACTCCTCGCATGTGAAGA CAATCACATACTTTCCCGGGCAATTCCCACTCTTCCCGTCTTGCCCGGTCAAAGCCACTTTGAGAGAGTCTTTGA TTATAAGCCTGCAGCCATGGATTCGGCTATCGTTGCCCAAGAATTGCTTCAATATCTTCGCTTTGGATACCCTCC GATTTTGCTAGGGTTTATCTTTATCGTCTTTTTGGTCCATTCCTCTCAGGTGGCCAGAAATGCTGATCGCAACAT TAAAGTCCAGTATGGCCCCAATGGGAAACCACTGCCTAGGCGAACCCGAATGATGATGGCGGTGGCCAGGGACTT GCCCGCGGAGCTTGCGCGGAATAGATCCAAGGGCTGGTTTGTTTGGCTGGATCTGTTTGTGCTGGCAACCTATAT TGCTGAGGCAGCAATTCATATGACCCATGCCATAGTTTCAAAGTCAGAGCAGTGGTGGTGTGGTCAAGCGGTAGT GGTGCGATACCTGTTTCCAAAATTGAAAGCAAAGCTAATTAAACCTAGTTCTTTGTCGTCGGGGCTTTCTTCACT CATACCGTTATCTTCATCTCTTTACTCGAGAACCGTGGACCGTCAATCGCGCAATTCGTCCCATGGCTCTCGGCC ATTCCCTTCGAGATAGCCATTCTCTCAACTTCAATCTCAATCTATTCCCACATCCACCATGAACCTACAATCGAA GATCCATTCGGTGGAAGATTGCGTACAAAGATCACATTTTGGGAGGCATTGGAGATTTCCGCAGGTTCAGTGCGG ATTTTTGTTCTCACACTGCTGGTCGCGTCCTACATTTTCAAATCTGCCCGCAAACATTGCGCATTCAAGGAGGCT GAGGATGCCGATGCCGGAGAGACGACTAGCCTGCTAGATTCAAGAGGCAATGCCAACTCGGATGATGGTGATGCC TTGACCGATGGTCAACAGACCCCGGAAGTAGAAGCATGGGTGCGGCCTTTGACGACCCCTTCCACCAACTGGATG GAATATCTGAGTGGCTATTCCCTATTCTTTCCATATCTGTGGCCTTACAAGTCTCTCCGGTTGCAAATTGTCGTC GTCATGTGCTTTGCTATATTGATTGTGCAGCGAGCGGTAAATATCCTAGTCCCATATCAAGTGGGAGTGATCGCA GACTCATTGTCCACCAGCGATGGAAATCTGAAAGTGCCTTGGATGCCCATCTGTCTGTATATCATCTACCGTTGG CTTCAAGGTAGTCAAGGTTTCCTTGAGTCGGTTCGCTCGAATCTGTGGATCTCAGTGAGCCAGTATGCATACATG GAGTTGTCAACCGCTTCATTTGAGCATGTTCATAACCTAGGACTGGACTTTCACCTGGGTAAAAAGATGGGCGAG GTTCTCTCTGCCCTCACCAAAGGCAACTCAATCAACACTTTTCTTGAGCAAGTGACATTTCAAGTGTTGCCGATG TTCATTGATTTGACCATCGCCATTGGTTATTTTCTAATCGTATTTGACGTGTACTACGCGTTGGCTGTTGCTGTC ATGACATTCTTCTACCTCTATTCAACCATCAAGATTGCCTCTTGGAGGGCCAATATGCGACGTCAAATGGTGAAC GCTTCCAGACAGGAAGACGCTGTCAAGTAAGTTTGTATTACGTCTCTGTTTATCTCATTACGCTTTACTAACCTA CACAGGAATGATTCCCTTGTGTCCTACGAAACTGTCAAATACTTCAACGCAGAGGAATACGAGTTCAATCGCTAT CGAGGAGCGGTCTCAGACTACCTCCGTGCGGAATGGCATTCCCTATTCGCACAGAATCTGATGAATATTTGCCAG AATGTCATTTTCATGTTTGGCCTTCTCATCACCTGTTTTATTTGTGCCTACCAAGTTGCTCGTGGTCAACGTCCA GTCGGCCAGTTCGTGACGCTCCTTACCTACATGGCCCAACTGCAAGCCCCATTGAACATCTTCGGAACCTTCTAC CGGTACATTCAATCAGCGTTGATCAACGCAGAGCGTCTACTCGAGCTTTTCCGCGTCCAGCCATCGGTAGTGGAT GCACCGTCTGCAACACCGCTAGCAGTCTGTCACGGCCGAATCACATTTAACGAGATCAAATTCTCGTATGACACC CGACGACCTGCTCTCAACGGATTGACCTTTGACTGTAAACCGGGTACAACTACAGCTCTGGTAGGAGAATCAGGT GGCGGGAAATCGACAATCTTCCGCTTGCTCTATAGGTTCTACAATCCGAGCAGCGGAAATCTTCTTATTGACGGA TACGATACGCAGACCTTGACAATTGATTCGGTACGCAGACACATTGGCGTCGTCCCACAAGACACCGTTCTCTTC AACGAAACAATCATGTACAACCTCAAATATGCCAACCAAAACGCCACCGACGAGGAAGTCTACGAGGCCTGCCGT GCAGCCAGTGTACACGACAAGATCATGGCGTTCCCCGACGGTTACGAAACCAAAGTGGGAGATCGTGGATTACGA CTAAGTGGTGGTGAGAAACAGCGCGTCGCCATTGCCCGAACCATTATCAAGAAACCTCAGATCATCCTGCTTGAT GAGGCAACGGCCGCATTAGATTCCGAGACGGAGCAGAACATTCAAGAAGCACTAGCCATCCTGTCACGTGGGCGC ACAGTGCTAGTAATTGCCCATCGGCTGAGCACCATCACCACTGCTGATAACATTGTTGTATTGCACGAAGGTCGG GTTGCAGAGACTGGGACCCATGAGCAACTTCTGGCTGCTAATGGTCGATATAAAGCTATGTGGCAGAAGCAGATT CGTGCACAGACCGAATCTGTGGGCTTGAATGCCTTGTCAGGCAAGATATAG