Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g6777.t1
Gene name
Location	scaffold_19:179..5855
Strand	-
Gene length (bp)	5676
Transcript length (bp)	3333
Coding sequence length (bp)	3333
Protein length (aa)	1111

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF02127	Peptidase_M18	Aminopeptidase I zinc metalloprotease (M18)	1.7E-163	13	458
PF13401	AAA_22	AAA domain	3.5E-06	753	902

GO

GO Term	Description	Terminal node
GO:0006508	proteolysis	Yes
GO:0008270	zinc ion binding	Yes
GO:0004177	aminopeptidase activity	Yes
GO:0071704	organic substance metabolic process	No
GO:0003824	catalytic activity	No
GO:0008233	peptidase activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0046872	metal ion binding	No
GO:0043167	ion binding	No
GO:0008238	exopeptidase activity	No
GO:0019538	protein metabolic process	No
GO:0008150	biological_process	No
GO:0044238	primary metabolic process	No
GO:0043170	macromolecule metabolic process	No
GO:0008152	metabolic process	No
GO:0005488	binding	No
GO:0046914	transition metal ion binding	No
GO:0003674	molecular_function	No
GO:0006807	nitrogen compound metabolic process	No
GO:0016787	hydrolase activity	No
GO:0043169	cation binding	No
GO:1901564	organonitrogen compound metabolic process	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 17	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g6777.t1 MAAKQPALDFLTFVNAAPTPFHAVHEAKQLLDKAGFQEIKERDSWASTCQPGGKYYLTRNTTTLVAFAIGKQWQP GNAISMIGAHTDSPVLRVKPVSKKSGEGFVQVGVETYGGGIWHTWFDRDLGVAGRVMTRESDGSIVQKLVKIDRP ILRVPTLAIHLDRQENFSFNKETQLFPIAGLIAAELNRNDGADTPDTDKGGELFSPLKSVTERHHSHFVELIANE AGVSPSDILDFEMILFDTQKSCLGGMLEEFIFSPRLDNLNSTFCATVGLIDSVADKSALDDEEAIRLIALFDHEE IGSRTAQGADSNILPSIIRRLSVLPSSSSKSTDLSTAYEQTLSTSFLVSADMAHSVNPNYSGKYESDHKPEMNKG LVIKINANARYATNSPGIVLLEEIARKTTKETGVHVPLQLFVVRNDSSCGSTIGPMLSAALGARTLDLGNPQLSM HSIRETGALREALIEFEGILTEEQRGLYKVSATKPDVASVIAFVTEIDANNSTTRRCVAPRLCTFLEATQQFSDV VGTFISSNPQIAALIWGGVKMAILTASNITSYFDKVTKMIMEIGRSCPTYQQFGQLYPDCISLQRELCEYYAAIV QLCTKIIEVSRRPPITQTLSSIFNPFESDFKSPLDKLKQATKDIQLQISLASKQANEETKKLLENESQNNAASRK LTNKFRKETQKEHTEAHQWRIHMMKREAASLRSSIRQNLSTIDYVKPWKQAIQQRVPSTAEWLLQEFLFHDWQDD QNTAILWCPGTMGMGKTVLISNVVAQLHASRNTNDIISYYICRADNTASLSARNIIGSLARQILDSQIKHAEDES LQRLYEDSNDLNTAEVVDFVLSRLHDDNTYYLAIDGLDECEPVEIRKVAQSVAKLCNMRVKNFKVLYTGRPELEN QLFGAMKPKYKIPVTETKVDLEMDRYIAAAIGNCLEDKQLILGDPTLIVKIFETLKKGSNGMFLWTRLFIEELCE QGSDSDILDALKHPPRGLSEIFDRKLSRVRERTLGKDAFKILQFCGVMKRPLTAMEYQEVLGLFPGQMSLDRKKL PNDMNKREMDEQRSRQQRKEVISRSWSDFSLQQQMSMRPPQRKMDEQPFKQQRKEAIFRW*
Coding	>Pro_DTO377G3_2|g6777.t1 ATGGCTGCCAAGCAACCTGCTCTGGACTTCTTGACCTTTGTCAATGCTGCTCCTACCCCTTTCCATGCCGTCCAC GAAGCGAAACAGCTTCTGGATAAGGCTGGCTTTCAAGAAATCAAGGAAAGAGACTCTTGGGCGTCGACCTGCCAA CCGGGAGGCAAGTACTACTTGACTCGCAACACTACTACCCTCGTGGCTTTTGCGATCGGCAAGCAATGGCAGCCG GGCAATGCCATCTCTATGATCGGTGCCCACACCGACTCTCCGGTGTTGAGGGTCAAACCCGTTAGCAAGAAGAGC GGGGAAGGCTTCGTCCAGGTCGGTGTAGAGACCTACGGCGGAGGCATCTGGCACACTTGGTTCGATCGTGATCTC GGTGTCGCTGGGCGGGTTATGACTCGCGAAAGCGATGGATCCATCGTGCAGAAACTGGTCAAGATTGACCGTCCC ATCCTCCGTGTTCCAACACTGGCCATCCATCTGGACCGCCAGGAAAACTTTTCATTCAATAAGGAAACACAGCTG TTCCCTATCGCTGGCCTTATTGCTGCAGAGCTTAACCGCAATGATGGAGCCGACACCCCTGATACAGACAAGGGT GGGGAATTATTCTCACCATTGAAATCTGTCACAGAACGTCACCACTCTCACTTCGTTGAGCTTATTGCTAACGAG GCTGGTGTCAGTCCCAGTGATATTCTGGACTTTGAAATGATCCTCTTCGACACTCAAAAGTCCTGTCTCGGCGGT ATGCTGGAGGAATTCATCTTCTCCCCTCGTCTAGACAACCTGAACAGCACTTTCTGTGCTACAGTTGGTCTGATT GACTCCGTGGCCGATAAATCAGCCCTCGACGACGAGGAAGCGATCCGCCTGATTGCCTTGTTTGACCACGAGGAA ATCGGAAGCCGCACAGCACAGGGTGCGGACTCGAACATTCTTCCATCGATCATTCGCCGTCTATCCGTCCTCCCA TCCTCCTCCTCCAAGAGCACCGACCTGTCAACTGCCTACGAGCAGACTCTGTCCACCTCCTTCCTTGTCTCTGCC GACATGGCTCATTCGGTCAACCCGAACTATTCGGGGAAGTACGAATCAGACCATAAGCCGGAGATGAACAAAGGC TTGGTGATTAAGATCAACGCCAACGCTCGCTATGCGACGAACTCTCCTGGAATTGTTCTCCTGGAGGAGATTGCG CGCAAGACCACCAAGGAGACTGGCGTCCACGTTCCTCTTCAGCTCTTTGTGGTCCGTAATGACTCGAGCTGTGGC AGCACCATTGGCCCTATGCTGTCTGCTGCGCTGGGCGCGCGGACACTTGATCTAGGCAATCCCCAGCTCAGTATG CACAGTATCCGTGAAACAGGTGCTCTCCGGGAGGCGTTGATTGAATTCGAGGGTATTCTGACGGAGGAGCAAAGG GGACTCTATAAAGTCAGCGCTACGAAACCAGACGTTGCGAGCGTCATCGCATTCGTGACGGAGATCGACGCCAAC AACAGCACGACAAGGAGATGTGTGGCACCGAGGTTGTGTACATTTCTGGAGGCGACACAACAGTTCAGTGATGTC GTGGGTACATTTATCAGCTCCAATCCTCAAATCGCCGCCCTAATCTGGGGCGGCGTTAAGATGGCTATATTGACG GCAAGCAATATTACATCTTACTTCGACAAGGTCACAAAAATGATTATGGAGATCGGAAGGTCGTGTCCAACCTAT CAACAATTTGGTCAACTTTATCCCGACTGTATCAGCCTTCAACGTGAGCTATGCGAGTACTATGCAGCCATCGTC CAATTGTGTACCAAGATCATCGAAGTATCAAGACGCCCGCCGATCACGCAAACTTTATCGTCTATTTTCAATCCC TTCGAGTCTGATTTCAAAAGCCCTCTCGATAAACTAAAGCAAGCTACAAAGGACATACAGCTGCAGATATCACTT GCCTCAAAGCAGGCTAACGAGGAAACAAAAAAATTGCTGGAAAACGAGAGCCAAAATAACGCAGCATCCCGAAAG TTGACAAATAAATTCCGAAAAGAAACCCAAAAGGAACACACTGAGGCGCACCAGTGGAGAATCCACATGATGAAG AGGGAAGCTGCAAGCTTGAGATCTAGCATTAGACAAAATCTTTCTACCATCGACTACGTCAAACCCTGGAAGCAA GCTATCCAACAACGCGTGCCCTCCACAGCGGAGTGGCTACTGCAAGAGTTCCTTTTCCATGATTGGCAAGATGAC CAAAATACTGCAATTCTCTGGTGCCCAGGCACGATGGGTATGGGAAAGACAGTGCTTATATCTAATGTGGTTGCC CAACTTCATGCCTCACGAAATACCAATGACATTATTTCCTATTACATTTGTCGTGCGGACAACACTGCATCTCTG TCAGCGAGAAACATTATCGGGAGTCTTGCTCGTCAAATATTAGACTCTCAGATCAAACACGCTGAAGATGAAAGT CTACAACGCCTATACGAGGATAGCAATGACCTCAATACGGCTGAAGTAGTTGATTTCGTACTGTCTCGGCTCCAC GATGACAATACATACTATCTAGCTATTGATGGACTGGATGAATGTGAACCTGTCGAGATCCGGAAGGTGGCGCAG AGTGTGGCCAAACTTTGTAACATGCGCGTTAAAAACTTCAAAGTTCTCTATACAGGCCGCCCGGAGCTTGAAAAC CAATTGTTTGGAGCCATGAAACCCAAATACAAAATCCCGGTGACCGAGACAAAAGTTGACTTGGAGATGGATCGC TATATTGCCGCGGCTATAGGCAACTGCCTAGAAGACAAACAATTGATCTTGGGGGATCCCACGCTCATTGTGAAG ATATTTGAAACCCTAAAAAAGGGATCCAACGGAATGTTCCTCTGGACGCGTCTTTTCATCGAAGAGCTCTGCGAA CAAGGCAGTGACAGCGACATCTTAGATGCATTGAAGCATCCCCCTCGTGGCCTATCTGAAATATTTGACAGAAAA CTCAGCCGTGTACGGGAGAGAACCTTGGGAAAAGACGCGTTCAAAATTCTCCAATTTTGTGGTGTGATGAAGCGG CCATTGACAGCGATGGAATACCAGGAGGTTTTAGGTCTTTTTCCTGGACAAATGTCTCTTGACCGAAAAAAGCTC CCCAACGACATGAATAAGAGGGAAATGGACGAACAGCGCTCCAGGCAGCAGCGCAAGGAGGTCATCTCAAGGTCG TGGAGCGACTTCTCGCTGCAACAGCAAATGTCAATGCGCCCGCCGCAGAGGAAAATGGACGAACAGCCCTTCAAG CAGCAGCGGAAGGAGGCCATCTTCAGGTGGTAG
Transcript	>Pro_DTO377G3_2|g6777.t1 ATGGCTGCCAAGCAACCTGCTCTGGACTTCTTGACCTTTGTCAATGCTGCTCCTACCCCTTTCCATGCCGTCCAC GAAGCGAAACAGCTTCTGGATAAGGCTGGCTTTCAAGAAATCAAGGAAAGAGACTCTTGGGCGTCGACCTGCCAA CCGGGAGGCAAGTACTACTTGACTCGCAACACTACTACCCTCGTGGCTTTTGCGATCGGCAAGCAATGGCAGCCG GGCAATGCCATCTCTATGATCGGTGCCCACACCGACTCTCCGGTGTTGAGGGTCAAACCCGTTAGCAAGAAGAGC GGGGAAGGCTTCGTCCAGGTCGGTGTAGAGACCTACGGCGGAGGCATCTGGCACACTTGGTTCGATCGTGATCTC GGTGTCGCTGGGCGGGTTATGACTCGCGAAAGCGATGGATCCATCGTGCAGAAACTGGTCAAGATTGACCGTCCC ATCCTCCGTGTTCCAACACTGGCCATCCATCTGGACCGCCAGGAAAACTTTTCATTCAATAAGGAAACACAGCTG TTCCCTATCGCTGGCCTTATTGCTGCAGAGCTTAACCGCAATGATGGAGCCGACACCCCTGATACAGACAAGGGT GGGGAATTATTCTCACCATTGAAATCTGTCACAGAACGTCACCACTCTCACTTCGTTGAGCTTATTGCTAACGAG GCTGGTGTCAGTCCCAGTGATATTCTGGACTTTGAAATGATCCTCTTCGACACTCAAAAGTCCTGTCTCGGCGGT ATGCTGGAGGAATTCATCTTCTCCCCTCGTCTAGACAACCTGAACAGCACTTTCTGTGCTACAGTTGGTCTGATT GACTCCGTGGCCGATAAATCAGCCCTCGACGACGAGGAAGCGATCCGCCTGATTGCCTTGTTTGACCACGAGGAA ATCGGAAGCCGCACAGCACAGGGTGCGGACTCGAACATTCTTCCATCGATCATTCGCCGTCTATCCGTCCTCCCA TCCTCCTCCTCCAAGAGCACCGACCTGTCAACTGCCTACGAGCAGACTCTGTCCACCTCCTTCCTTGTCTCTGCC GACATGGCTCATTCGGTCAACCCGAACTATTCGGGGAAGTACGAATCAGACCATAAGCCGGAGATGAACAAAGGC TTGGTGATTAAGATCAACGCCAACGCTCGCTATGCGACGAACTCTCCTGGAATTGTTCTCCTGGAGGAGATTGCG CGCAAGACCACCAAGGAGACTGGCGTCCACGTTCCTCTTCAGCTCTTTGTGGTCCGTAATGACTCGAGCTGTGGC AGCACCATTGGCCCTATGCTGTCTGCTGCGCTGGGCGCGCGGACACTTGATCTAGGCAATCCCCAGCTCAGTATG CACAGTATCCGTGAAACAGGTGCTCTCCGGGAGGCGTTGATTGAATTCGAGGGTATTCTGACGGAGGAGCAAAGG GGACTCTATAAAGTCAGCGCTACGAAACCAGACGTTGCGAGCGTCATCGCATTCGTGACGGAGATCGACGCCAAC AACAGCACGACAAGGAGATGTGTGGCACCGAGGTTGTGTACATTTCTGGAGGCGACACAACAGTTCAGTGATGTC GTGGGTACATTTATCAGCTCCAATCCTCAAATCGCCGCCCTAATCTGGGGCGGCGTTAAGATGGCTATATTGACG GCAAGCAATATTACATCTTACTTCGACAAGGTCACAAAAATGATTATGGAGATCGGAAGGTCGTGTCCAACCTAT CAACAATTTGGTCAACTTTATCCCGACTGTATCAGCCTTCAACGTGAGCTATGCGAGTACTATGCAGCCATCGTC CAATTGTGTACCAAGATCATCGAAGTATCAAGACGCCCGCCGATCACGCAAACTTTATCGTCTATTTTCAATCCC TTCGAGTCTGATTTCAAAAGCCCTCTCGATAAACTAAAGCAAGCTACAAAGGACATACAGCTGCAGATATCACTT GCCTCAAAGCAGGCTAACGAGGAAACAAAAAAATTGCTGGAAAACGAGAGCCAAAATAACGCAGCATCCCGAAAG TTGACAAATAAATTCCGAAAAGAAACCCAAAAGGAACACACTGAGGCGCACCAGTGGAGAATCCACATGATGAAG AGGGAAGCTGCAAGCTTGAGATCTAGCATTAGACAAAATCTTTCTACCATCGACTACGTCAAACCCTGGAAGCAA GCTATCCAACAACGCGTGCCCTCCACAGCGGAGTGGCTACTGCAAGAGTTCCTTTTCCATGATTGGCAAGATGAC CAAAATACTGCAATTCTCTGGTGCCCAGGCACGATGGGTATGGGAAAGACAGTGCTTATATCTAATGTGGTTGCC CAACTTCATGCCTCACGAAATACCAATGACATTATTTCCTATTACATTTGTCGTGCGGACAACACTGCATCTCTG TCAGCGAGAAACATTATCGGGAGTCTTGCTCGTCAAATATTAGACTCTCAGATCAAACACGCTGAAGATGAAAGT CTACAACGCCTATACGAGGATAGCAATGACCTCAATACGGCTGAAGTAGTTGATTTCGTACTGTCTCGGCTCCAC GATGACAATACATACTATCTAGCTATTGATGGACTGGATGAATGTGAACCTGTCGAGATCCGGAAGGTGGCGCAG AGTGTGGCCAAACTTTGTAACATGCGCGTTAAAAACTTCAAAGTTCTCTATACAGGCCGCCCGGAGCTTGAAAAC CAATTGTTTGGAGCCATGAAACCCAAATACAAAATCCCGGTGACCGAGACAAAAGTTGACTTGGAGATGGATCGC TATATTGCCGCGGCTATAGGCAACTGCCTAGAAGACAAACAATTGATCTTGGGGGATCCCACGCTCATTGTGAAG ATATTTGAAACCCTAAAAAAGGGATCCAACGGAATGTTCCTCTGGACGCGTCTTTTCATCGAAGAGCTCTGCGAA CAAGGCAGTGACAGCGACATCTTAGATGCATTGAAGCATCCCCCTCGTGGCCTATCTGAAATATTTGACAGAAAA CTCAGCCGTGTACGGGAGAGAACCTTGGGAAAAGACGCGTTCAAAATTCTCCAATTTTGTGGTGTGATGAAGCGG CCATTGACAGCGATGGAATACCAGGAGGTTTTAGGTCTTTTTCCTGGACAAATGTCTCTTGACCGAAAAAAGCTC CCCAACGACATGAATAAGAGGGAAATGGACGAACAGCGCTCCAGGCAGCAGCGCAAGGAGGTCATCTCAAGGTCG TGGAGCGACTTCTCGCTGCAACAGCAAATGTCAATGCGCCCGCCGCAGAGGAAAATGGACGAACAGCCCTTCAAG CAGCAGCGGAAGGAGGCCATCTTCAGGTGGTAG
Gene	>Pro_DTO377G3_2|g6777.t1 ATGGCTGCCAAGCAACCTGCTCTGGACTTCTTGACCTTTGTCAATGCTGCTCCTACCCGTATGTAGTTCTATCGA TGACGTGGAATGTCGCTGATTTGTCTTATCTCCAGCTTTCCATGCCGTCCACGAAGCGAAACAGCTTCTGGATAA GGCTGGCTTTCAAGAAATCAAGGTCGGCTCAAGCTGAATACCGGAGTAATAAATTGTGGCTCATCCATCAATAGG AAAGAGACTCTTGGGCGTCGACCTGCCAACCGGGAGGCAAGTACTACTTGACTCGCAACACTACTACCCTCGTGG CTTTTGCGATCGGCAAGCAATGGCAGGTATGTATAAATTGCGGAACTGCGTAAATGGTCTTTCAATTAATCATGT CAATGAATATAGCCGGGCAATGCCATCTCTATGATCGGTGCCCACACCGACTCTCCGGTGTTGAGGGTCAAACCC GTTAGCAAGAAGAGCGGGGAAGGCTTCGTCCAGGTCGGTGTAGAGACCTACGGCGGAGGCATCTGGCACACTTGT ACGTGCCATTGATTACCTTCAAACTATCATAGTCGCTAATTTCCTGCAGGGTTCGATCGTGATCTCGGTGTCGCT GGGCGGGTTATGACTCGCGAAAGCGATGGATCCATCGTGCAGAAACTGGTCAAGATTGACCGTCCCAGTATGTTT CATGTTGACCCAATAAATGTGCCTTGCTAACAAGGTAGTCCTCCGTGTTCCAACACTGGCCATCCATCTGGACCG CCAGGAAAACTTTTCATTCAATAAGGAAACACAGCTGTTCCCTATCGCTGGCCTTATTGCTGCAGAGCTTAACCG CAATGATGGAGCCGACACCCCTGATACAGACAAGGGTGGGGAATTATTCTCACCATTGAAATCTGTCACAGAACG TCACCACTCTCACTTCGTTGAGCTTATTGCTAACGAGGCTGGTGTCAGTCCCAGTGATATTCTGGACTTTGAAAT GATCCTCTTCGACACTCAAAAGTCCTGTCTCGGCGGTATGCTGGAGGAATTCATCTTCTCCCCTCGTCTAGACAA CCTGAACAGCACTTTCTGTGCTACAGTTGGTCTGATTGACTCCGTGGCCGATAAATCAGCCCTCGACGACGAGGA AGCGATCCGCCTGATTGCCTTGTTTGACCACGAGGAAATCGGAAGCCGCACAGCACAGGGTGCGGACTCGAACAT TCTTCCATCGATCATTCGCCGTCTATCCGTCCTCCCATCCTCCTCCTCCAAGAGCACCGACCTGTCAACTGCCTA CGAGCAGACTCTGTCCACCTCCTTCCTTGTCTCTGCCGACATGGCTCATTCGGTCAACCCGAACTATTCGGGGAA GTACGAATCAGACCATAAGCCGGAGATGAACAAAGGCTTGGTGATTAAGATCAACGCCAACGCTCGCTATGCGAC GAACTCTCCTGGAATTGTTCTCCTGGAGGAGATTGCGCGCAAGACCACCAAGGAGACTGGCGTCCACGTTCCTCT TCAGCTCTTTGTGGTCCGTAATGACTCGAGCTGTGGCAGCACCATTGGCCCTATGCTGTCTGCTGCGCTGGGCGC GCGGACACTTGATCTAGGCAATCCCCAGCTCAGTATGCACAGTATCCGTGAAACAGGTGGTACTTATGATGTTGC CCATGCCATTCGTTTGTTCACTGGCTTCTTCAAGCATTACTCAGAGCTGTCGAAGAAGATCATTGTGGATTAAGC TTACCGTGAATAAGTAGATGAAGTAGTACAATCAATACTATTCAAACAGTCCAGTATTCCATTTCCAAGCATTCG AATATAAACACTCAAACATCTTAAAATAAAACACAAACGTACTGTGCATGTACCTTGGGGAAAGCACGTGGTCCG GGCCGAGGAAAATCCACTACCCGAAGTATTAATATCCCAGATTCCCAGTAGTCTACACCAGAATATGAGGACCTG TAGAATTGACGCCAAAAACGGCCATTCTCTACCTCAAAAAGCAAAACAAAAACATACAACAGTGAGGATTCGCTG GTGGTCACCCACCCAACTACTACCCCGGACTATTCTTAGCCTCCGAATTTCTAATGCGATTGGTCTGCGATGGTC TGTCACCCCGCAACGTGATCCTTACGTAGGCGAGGAGCTTATAACTAGGTAACTCAGCGGCGTGTGGCTTATACG CAGTCGATAGTCGGGTGGGTGTCGCCCGGGTGAGAAATGGATGAGCGCCGTTTTACGGTCGCGCGACCGGGGGTG AGAAGGGTGAGTGTACTATACAATTCTTTACGCCAAGCGATACATGTACATCGTGTCTTGTTACTGTATGGAGTG GCTAGAACTTCCCATACTTTAGGCTAAGATTGTGCCGCTCTTCAGCTTGTTGCCTGACAAAACGTGGCTTAGACG TTTTACCACCCTCAGCCCCCTTCAGCTGAGGGGAATCGTATCTTTAGATTTGATCCGAACCCTCCCATCCCCTGT CCAAAAATTCGACAAATCGCAATTTCTTTGATATCAAGGCGGCCGCGGAGGACATGATGGCTTGTGTAGCATTGT CTCATTCCGGTTCGATACGGGTGCCGCATCCGACAACAGCTCTCCGGGAGGCGTTGATTGAATTCGAGGGTATTC TGACGGAGGAGCAAAGGGGACTCTATAAAGTCAGCGCTACGAAACCAGACGTTGCGAGCGTCATCGCATTCGTGA CGGAGATCGACGCCAACAACAGCACGACAAGGAGATGTGTGGCACCGAGGTTGTGTACATTTCTGGAGGCGACAC AACAGTTCAGTGATGTCGTGGGTACATTTATCAGCTCCAATCCTCAAATCGCCGCCCTAATCTGGGGCGGCGTTA AGATGGCTATATTGACGGCAAGCAATATTACATCTTACTTCGACAAGGTCACAAAAATGATTATGGAGATCGGAA GGTCGTGTCCAACCTATCAACAATTTGGTCAACTTTATCCCGACTGTATCAGCCTTCAACGTGAGCTATGCGAGT ACTATGCAGCCATCGTCCAATTGTGTACCAAGATCATCGAAGTATCAAGACGCCCGCCGATCACGCAAACTTTAT CGTCTATTTTCAATCCCTTCGAGTCTGATTTCAAAAGCCCTCTCGATAAACTAAAGCAAGCTACAAAGGACATAC AGCTGCAGATATCACTTGCCTCAAAGCAGGCTAACGAGGAAACAAAAAAATTGCTGGAAAACGAGAGCCAAAATA ACGCAGCATCCCGAAAGTTGACAAATAAATTCCGAAAAGAAACCCAAAAGGAACACACTGAGGCGCACCAGTGGA GAATCCACATGATGAAGAGGGAAGCTGCAAGCTTGAGATCTAGCATTAGACAAAATCTTTCTACCATCGACTACG TCAAACCCTGGAAGCAAGCTATCCAACAACGCGTGCCCTCCACAGCGGAGTGGCTACTGCAAGAGTTCCTTTTCC ATGATTGGCAAGATGACCAAAATACTGCAATTCTCTGGTGCCCAGGCACGATGGGTATGGGAAAGACAGTGCTTA TATCTAATGTGGTTGCCCAACTTCATGCCTCACGAAATACCAATGACATTATTTCCTATTACATTTGTCGTGCGG ACAACACTGCATCTCTGTCAGCGAGAAACATTATCGGGAGTCTTGCTCGTCAAATATTAGACTCTCAGATCAAAC ACGCTGAAGATGAAAGTCTACAACGCCTATACGAGGATAGCAATGACCTCAATACGGCTGAAGTAGTTGATTTCG TACTGTCTCGGCTCCACGATGACAATACATACTATCTAGCTATTGATGGACTGGATGAATGTGAACCTGTCGAGA TCCGGAAGGTGGCGCAGAGTGTGGCCAAACTTTGTAACATGCGCGTTAAAAACTTCAAAGTTCTCTATACAGGCC GCCCGGAGCTTGAAAACCAATTGTTTGGAGCCATGAAACCCAAATACAAAATCCCGGTGACCGAGACAAAAGTTG ACTTGGAGATGGATCGCTATATTGCCGCGGCTATAGGCAACTGCCTAGAAGACAAACAATTGATCTTGGGGGATC CCACGCTCATTGTGAAGATATTTGAAACCCTAAAAAAGGGATCCAACGGAATGTAAGTGATGAAATGATCCAATT CAAGCGACGGGATGAGGGGTTTTCCACCATCTTTATCAATCGAGCTAGGCATGAAGTCCTGGTGAATTCTTTATC ATTAGGAGTGAAAGTTGTTGGACTTTTATGTTGCAAGTATCTAGGCTGATCGATAAAGGTTCCTCTGGACGCGTC TTTTCATCGAAGAGCTCTGCGAACAAGGCAGTGACAGCGACATCTTAGATGCATTGAAGCATCCCCCTCGTGGCC TATCTGAAATATTTGACAGAAAACTCAGCCGTGTACGGGAGAGAACCTTGGGAAAAGACGCGTTCAAAATTCTCC AATTTTGTGGTGTGATGAAGCGGCCATTGACAGCGATGGAATACCAGGAGGTTTTAGGTCTTTTTCCTGGACAAA TGTCTCTTGACCGAAAAAAGCTCCCCAACGACATGAATAAGGTCATTGGTGATTGTTGTGGTCTAACATTCATCG ACGAAGAGGACAGCACTGTGCACTATGTTCATCATAGCGTGAAGAAACACCTTTTTGGCACGAACTCCCGACACT CGGAGGAATTCAATATGGCGGGACTTGATTGGCATATCGGCGTTCTTTGCATGACCTACCTCGATTTCACTGATT TTAAGCGTCAGTTGACGAAAATTCAGAATGGTTCAAATACTCCTATACGGCCTGTTCAGCTTGGAATGTCCCCCT TCGGCAGTTACAGCAGTATGACTGGTCGAATGGCACTGAGGCTACTTTCTTACCGTGAGAAGTTACGGCATCTCA GCGCTGGGGAGCTAGAGAGGAAGGCCCAACAAATACTTGGTGACAAAGAGTCTTCACGTCTAGAGATGGAACTCC AAAGCCGAGGTTTTCACTTTCTCGAATACGCCCGAAATCACTGGATCAATCACCTCACAAACCCACATCCCGAAT CTGAGGATATGGCTTGGTCATTGTTCTGCCGATGTGTAGAAGGGAATGATATTGTTGCATACAGACCATGGGAGT CAGCGCAGAAGGCCTACGAAGATAGAAACGATGTACCGCAGACGATACAATGGTTGTCAGCATATGGACATTATC ACTTGCTTTTGTACTATATAAGGCGTCAGCCTTATATTTTAACAGAGAACATCAAGCGTCATATACTTCGAAGTT CCATCACCAATGGCCATCATCGTCTCGCCAGGTGTATTATCCAACACGGACGCGATTCTCCTGCTCTCATGAATC ATGGATTGTTTTTGGTTTCGAGAGAAGGTTGCAGTGAATTACTACCAAGTCTGCTCCAAGTAGTCACCCACGTGG ATGCACGAGTGTGTGGCCAAACAGCGCTCCAAGCAGCAGCGCAAGGAGGCCATCTTCAGGTGGTAGAGCGACTTC TCGCAGCAACGGCAAATGTCAATGCACCCGCCGCAGAGGGAAATGGACGAACAGCGCTCCAGGCAGCAGCGCAAG GAGGTCATCTCAAGGTCGTGGAGCGACTTCTCGCTGCAACAGCAAATGTCAATGCGCCCGCCGCAGAGGAAAATG GACGAACAGCCCTTCAAGCAGCAGCGGAAGGAGGCCATCTTCAGGTGGTAG