Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g6593.t1
Gene name
Location	scaffold_18:6509..10249
Strand	-
Gene length (bp)	3740
Transcript length (bp)	3672
Coding sequence length (bp)	3672
Protein length (aa)	1224

Your browser does not support drawing a protein figure.

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF02518	HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	7.5E-17	794	926
PF00072	Response_reg	Response regulator receiver domain	1.6E-15	1075	1191
PF00512	HisKA	His Kinase A (phospho-acceptor) domain	1.1E-11	685	748

GO

GO Term	Description	Terminal node
GO:0007165	signal transduction	Yes
GO:0000160	phosphorelay signal transduction system	Yes
GO:0000155	phosphorelay sensor kinase activity	Yes
GO:0003824	catalytic activity	No
GO:0140299	small molecule sensor activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0004672	protein kinase activity	No
GO:0016772	transferase activity, transferring phosphorus-containing groups	No
GO:0008150	biological_process	No
GO:0016740	transferase activity	No
GO:0004673	protein histidine kinase activity	No
GO:0050789	regulation of biological process	No
GO:0016301	kinase activity	No
GO:0065007	biological regulation	No
GO:0003674	molecular_function	No
GO:0035556	intracellular signal transduction	No
GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	No
GO:0050794	regulation of cellular process	No
GO:0009987	cellular process	No
GO:0016773	phosphotransferase activity, alcohol group as acceptor	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 49	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

Click here for more information

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g6593.t1 MSDNKTEVSTVAELLSPKLKLPQLGTESAERVFPVRSVVSFDSTPSSALQTPSLDKLETPISPFSDTWSAGFSNE QAGSQQKSPPGKSTNAEDGVSKRSDHPTQPRAENEIPSVLKGQPCSSHNLDILAQLKTTVQNGGEILDIHKSTKG ICYSHEDEENIFTQSFGALVVIKESDGNFEVHIASENSKEIIQHSPDQLFGLRTFCDILPSSQHSNFLAHSKFVL SDDYSVQDSGPEVFFLCVLSPDGYIQGTWCTMHTSTVYKDYIICELQPEPRGTKVQPDLENPEIQTTKADSQTLD MTSGAFPENINPPGKDLDTRNSKFPDPSELLNTIPRILQRFATAQTLEALVQNTIATLQNIIEFDRTTMYHFDID RNGIVVADAVDGSSGLTSYEGVHFPESTFPEGLKKLYTRNTVCCSCSRSQGSSKLVYRASTNKRPLDMSNTYIHA APAPLTPHTENPVRACLSIQINVFGKLWGLISCQSYDSGQMLHPLIQKVCWFVAEAVSSNIERLSYTLPFQFREP DISLDKTRTSQAIKTPPGDLLSLFGADYAAASIMGEAKILGKPIDSQEVLALFEYMKAKENDTVFWSADIAADFR DLNYSPGFHHLSGLLYVPLSIDGRDFIIFFRADLESHNLASNSSRQHEWSSAEFGKASVLSLLYRTFTDIWQEKE VTLQNNQLMRLLLANSAHEFRTPLNAIINYLEIVLDGSLDQETRDHISRSHSASKSLVYIINDLLDLTNTENGQK LIKDEVLDLSETLTEATDIFWEEARQKHVDLQVVQHAALPPVLGDQRRVRQVITNLISNAIQHTSTGAVTIESCV VPEPLETDHICVEVAIHDTGSGMSQQTVETLFCELEQVSNKGYMQNPNSFEHTSSGRVFETESVLGLGLALVARI VRNMNGQLSLKSEEGKGSCFKIRLVFPLPGEDSIQKQNSCATSNGHVQGDERKEDTKKDTTSSNCVTNQNEGGIP CECGQSPEFESGKCVVHAEVGLKTGESRKLSLSGEQLDQSHQPQVPAAFLPKEDPGQSSEASKSPVKELFSISPP TKSPTDQPQPPQPSVSPTMDWNLHVLVAEDDPINSTIMQKRLEKFGHTVHMTSNGKECLSAYKADPTHFDAVLMD LQMPIVDGLGATQMIREYEQELANGDTPAPRIPIFAVSASLLEENRKMYMDSGFDGWVMKPIDFHRVDRLLGGVR LQWVRQEVVYRPGVWEAGGWFEA*
Coding	>Pro_DTO377G3_2|g6593.t1 ATGTCTGACAACAAGACTGAAGTATCGACGGTAGCCGAGCTGCTATCCCCGAAGTTGAAATTGCCTCAACTGGGC ACCGAATCGGCGGAAAGAGTCTTTCCTGTTCGTTCCGTCGTCTCATTTGATTCCACACCTTCATCCGCCCTGCAG ACACCTTCCCTCGATAAGCTCGAAACACCGATATCTCCTTTTTCGGACACATGGAGTGCAGGCTTCAGCAATGAA CAAGCGGGCTCTCAGCAGAAAAGTCCACCTGGGAAGAGTACGAATGCTGAGGATGGTGTCTCAAAGAGATCCGAC CATCCCACTCAACCGCGTGCTGAGAATGAAATTCCATCGGTACTCAAAGGACAACCTTGCTCCAGCCATAATCTT GACATTTTGGCACAATTGAAAACCACTGTGCAAAACGGTGGCGAAATCCTTGACATCCACAAATCAACAAAGGGG ATATGCTACTCGCATGAAGATGAAGAGAACATCTTCACTCAGTCATTCGGCGCACTGGTTGTGATAAAAGAGTCC GACGGTAACTTTGAAGTGCATATAGCAAGTGAAAACTCCAAGGAAATCATACAGCATTCTCCTGATCAACTCTTC GGGCTTCGAACATTTTGTGATATATTGCCATCATCGCAACACAGCAACTTTCTTGCTCATTCTAAATTCGTTTTG AGCGACGACTACTCAGTCCAGGACTCTGGTCCTGAGGTCTTCTTCCTTTGTGTATTGTCACCTGACGGATATATT CAGGGTACTTGGTGTACCATGCATACGAGCACAGTATATAAAGACTATATCATTTGCGAGCTTCAGCCCGAGCCT CGAGGGACAAAGGTTCAGCCCGATTTGGAGAACCCCGAAATTCAAACGACAAAAGCGGATAGCCAGACCTTGGAC ATGACCTCTGGAGCATTTCCTGAGAATATCAATCCTCCGGGAAAAGACCTTGATACCAGAAATAGCAAATTTCCC GACCCATCGGAGCTTCTCAATACCATCCCTCGAATCCTCCAGCGATTTGCAACTGCTCAAACGCTAGAAGCGCTC GTTCAAAATACCATCGCCACTCTGCAGAATATCATTGAATTTGACAGAACTACCATGTATCATTTCGATATTGAC CGCAACGGAATTGTGGTCGCCGATGCAGTTGATGGTTCGTCGGGGTTAACTTCGTACGAAGGCGTGCATTTCCCG GAATCAACCTTCCCCGAAGGATTGAAGAAACTATACACACGCAATACTGTATGCTGCTCTTGTTCTAGAAGCCAG GGCAGTTCAAAACTTGTGTATCGGGCTTCCACCAACAAAAGGCCCCTCGACATGTCAAACACCTATATCCATGCA GCACCGGCGCCCTTAACGCCGCATACCGAGAATCCCGTCAGGGCCTGTTTGTCAATCCAAATCAATGTCTTTGGT AAGCTTTGGGGTCTCATATCATGTCAGTCCTACGACAGTGGCCAAATGCTCCATCCGCTCATCCAGAAAGTGTGC TGGTTTGTAGCCGAGGCGGTTTCAAGTAACATTGAGCGTCTGTCCTACACCTTACCCTTTCAATTTCGAGAGCCG GACATCTCTTTGGATAAAACGCGCACATCTCAGGCTATAAAGACCCCACCCGGTGATCTTCTCAGTCTGTTCGGG GCAGATTACGCTGCAGCGTCGATCATGGGCGAGGCCAAAATCTTGGGGAAACCAATCGACTCGCAGGAAGTTTTG GCATTGTTCGAATACATGAAAGCCAAAGAAAATGACACGGTGTTTTGGTCTGCAGATATCGCTGCCGATTTTCGG GATCTCAATTACTCGCCCGGCTTTCATCATCTTTCTGGTTTGCTTTACGTTCCTCTTTCCATTGATGGTCGTGAT TTTATCATCTTTTTTCGGGCTGATTTAGAGAGCCATAACCTTGCTTCTAATTCAAGCCGGCAACATGAATGGTCG TCGGCAGAGTTTGGAAAGGCATCTGTACTGTCTTTGCTCTATCGCACTTTCACCGATATATGGCAAGAGAAGGAG GTTACACTGCAGAACAACCAGTTGATGAGGCTTTTACTGGCTAATTCGGCGCACGAGTTCAGAACACCTCTAAAT GCGATCATCAACTACCTGGAGATTGTTCTCGATGGTTCTCTAGATCAAGAAACACGAGATCATATTTCCAGATCT CACTCGGCTTCTAAGTCGTTGGTATACATCATCAATGACCTTCTAGATCTCACGAATACGGAAAACGGGCAAAAG TTGATAAAGGACGAGGTATTAGATCTCTCCGAGACCCTCACGGAAGCAACAGACATATTCTGGGAAGAAGCAAGA CAGAAGCATGTCGATCTACAAGTAGTCCAACACGCAGCCCTACCTCCCGTCCTCGGAGATCAACGGCGGGTACGC CAGGTGATCACAAACTTGATCAGTAATGCTATACAGCACACATCTACCGGAGCAGTGACAATCGAGTCTTGTGTT GTTCCGGAGCCGCTGGAGACAGATCATATCTGTGTCGAAGTCGCAATACATGATACCGGGTCTGGCATGTCCCAA CAGACTGTCGAAACATTGTTCTGCGAGCTGGAACAAGTATCCAACAAGGGATATATGCAGAATCCCAACTCATTT GAACATACTTCAAGTGGCCGTGTATTCGAGACGGAAAGCGTGCTTGGCCTGGGCCTCGCACTGGTCGCCCGAATC GTGCGCAATATGAACGGTCAGCTAAGCTTGAAGTCTGAAGAAGGCAAGGGAAGTTGCTTCAAGATCAGGCTTGTG TTTCCTCTTCCGGGTGAAGATAGTATTCAAAAGCAGAACTCGTGTGCTACGTCAAACGGACATGTGCAGGGGGAT GAAAGAAAAGAAGACACAAAGAAAGACACCACATCCTCGAATTGCGTAACAAACCAGAACGAAGGGGGTATTCCA TGTGAATGTGGTCAAAGTCCAGAATTCGAATCAGGAAAATGCGTCGTGCACGCCGAGGTAGGCTTGAAAACCGGG GAATCGAGAAAGCTCTCCCTTTCTGGCGAACAGCTCGATCAGAGCCACCAGCCACAGGTACCGGCCGCTTTCCTT CCAAAAGAAGATCCTGGGCAATCATCAGAAGCGTCCAAATCTCCTGTCAAAGAACTCTTCTCGATCTCACCACCC ACAAAATCCCCTACCGACCAGCCCCAACCCCCTCAACCCAGCGTCTCTCCCACGATGGACTGGAACCTCCACGTC CTCGTCGCGGAAGACGACCCAATCAATAGCACCATCATGCAAAAGCGCCTTGAGAAATTCGGCCACACAGTGCAC ATGACAAGCAACGGCAAAGAATGCCTATCTGCCTATAAAGCTGATCCCACCCACTTTGACGCAGTGCTGATGGAT CTACAAATGCCCATCGTCGATGGCCTTGGTGCAACACAGATGATACGCGAATACGAGCAAGAGCTGGCTAATGGA GACACGCCTGCGCCTCGCATTCCCATTTTTGCTGTCTCGGCTTCCTTGCTCGAGGAGAATCGGAAGATGTACATG GATTCGGGCTTTGATGGATGGGTCATGAAGCCCATTGATTTCCACAGGGTTGATCGGTTGCTTGGGGGTGTTAGG CTTCAGTGGGTACGTCAGGAGGTTGTTTACCGGCCTGGTGTGTGGGAGGCTGGAGGGTGGTTTGAGGCATAG
Transcript	>Pro_DTO377G3_2|g6593.t1 ATGTCTGACAACAAGACTGAAGTATCGACGGTAGCCGAGCTGCTATCCCCGAAGTTGAAATTGCCTCAACTGGGC ACCGAATCGGCGGAAAGAGTCTTTCCTGTTCGTTCCGTCGTCTCATTTGATTCCACACCTTCATCCGCCCTGCAG ACACCTTCCCTCGATAAGCTCGAAACACCGATATCTCCTTTTTCGGACACATGGAGTGCAGGCTTCAGCAATGAA CAAGCGGGCTCTCAGCAGAAAAGTCCACCTGGGAAGAGTACGAATGCTGAGGATGGTGTCTCAAAGAGATCCGAC CATCCCACTCAACCGCGTGCTGAGAATGAAATTCCATCGGTACTCAAAGGACAACCTTGCTCCAGCCATAATCTT GACATTTTGGCACAATTGAAAACCACTGTGCAAAACGGTGGCGAAATCCTTGACATCCACAAATCAACAAAGGGG ATATGCTACTCGCATGAAGATGAAGAGAACATCTTCACTCAGTCATTCGGCGCACTGGTTGTGATAAAAGAGTCC GACGGTAACTTTGAAGTGCATATAGCAAGTGAAAACTCCAAGGAAATCATACAGCATTCTCCTGATCAACTCTTC GGGCTTCGAACATTTTGTGATATATTGCCATCATCGCAACACAGCAACTTTCTTGCTCATTCTAAATTCGTTTTG AGCGACGACTACTCAGTCCAGGACTCTGGTCCTGAGGTCTTCTTCCTTTGTGTATTGTCACCTGACGGATATATT CAGGGTACTTGGTGTACCATGCATACGAGCACAGTATATAAAGACTATATCATTTGCGAGCTTCAGCCCGAGCCT CGAGGGACAAAGGTTCAGCCCGATTTGGAGAACCCCGAAATTCAAACGACAAAAGCGGATAGCCAGACCTTGGAC ATGACCTCTGGAGCATTTCCTGAGAATATCAATCCTCCGGGAAAAGACCTTGATACCAGAAATAGCAAATTTCCC GACCCATCGGAGCTTCTCAATACCATCCCTCGAATCCTCCAGCGATTTGCAACTGCTCAAACGCTAGAAGCGCTC GTTCAAAATACCATCGCCACTCTGCAGAATATCATTGAATTTGACAGAACTACCATGTATCATTTCGATATTGAC CGCAACGGAATTGTGGTCGCCGATGCAGTTGATGGTTCGTCGGGGTTAACTTCGTACGAAGGCGTGCATTTCCCG GAATCAACCTTCCCCGAAGGATTGAAGAAACTATACACACGCAATACTGTATGCTGCTCTTGTTCTAGAAGCCAG GGCAGTTCAAAACTTGTGTATCGGGCTTCCACCAACAAAAGGCCCCTCGACATGTCAAACACCTATATCCATGCA GCACCGGCGCCCTTAACGCCGCATACCGAGAATCCCGTCAGGGCCTGTTTGTCAATCCAAATCAATGTCTTTGGT AAGCTTTGGGGTCTCATATCATGTCAGTCCTACGACAGTGGCCAAATGCTCCATCCGCTCATCCAGAAAGTGTGC TGGTTTGTAGCCGAGGCGGTTTCAAGTAACATTGAGCGTCTGTCCTACACCTTACCCTTTCAATTTCGAGAGCCG GACATCTCTTTGGATAAAACGCGCACATCTCAGGCTATAAAGACCCCACCCGGTGATCTTCTCAGTCTGTTCGGG GCAGATTACGCTGCAGCGTCGATCATGGGCGAGGCCAAAATCTTGGGGAAACCAATCGACTCGCAGGAAGTTTTG GCATTGTTCGAATACATGAAAGCCAAAGAAAATGACACGGTGTTTTGGTCTGCAGATATCGCTGCCGATTTTCGG GATCTCAATTACTCGCCCGGCTTTCATCATCTTTCTGGTTTGCTTTACGTTCCTCTTTCCATTGATGGTCGTGAT TTTATCATCTTTTTTCGGGCTGATTTAGAGAGCCATAACCTTGCTTCTAATTCAAGCCGGCAACATGAATGGTCG TCGGCAGAGTTTGGAAAGGCATCTGTACTGTCTTTGCTCTATCGCACTTTCACCGATATATGGCAAGAGAAGGAG GTTACACTGCAGAACAACCAGTTGATGAGGCTTTTACTGGCTAATTCGGCGCACGAGTTCAGAACACCTCTAAAT GCGATCATCAACTACCTGGAGATTGTTCTCGATGGTTCTCTAGATCAAGAAACACGAGATCATATTTCCAGATCT CACTCGGCTTCTAAGTCGTTGGTATACATCATCAATGACCTTCTAGATCTCACGAATACGGAAAACGGGCAAAAG TTGATAAAGGACGAGGTATTAGATCTCTCCGAGACCCTCACGGAAGCAACAGACATATTCTGGGAAGAAGCAAGA CAGAAGCATGTCGATCTACAAGTAGTCCAACACGCAGCCCTACCTCCCGTCCTCGGAGATCAACGGCGGGTACGC CAGGTGATCACAAACTTGATCAGTAATGCTATACAGCACACATCTACCGGAGCAGTGACAATCGAGTCTTGTGTT GTTCCGGAGCCGCTGGAGACAGATCATATCTGTGTCGAAGTCGCAATACATGATACCGGGTCTGGCATGTCCCAA CAGACTGTCGAAACATTGTTCTGCGAGCTGGAACAAGTATCCAACAAGGGATATATGCAGAATCCCAACTCATTT GAACATACTTCAAGTGGCCGTGTATTCGAGACGGAAAGCGTGCTTGGCCTGGGCCTCGCACTGGTCGCCCGAATC GTGCGCAATATGAACGGTCAGCTAAGCTTGAAGTCTGAAGAAGGCAAGGGAAGTTGCTTCAAGATCAGGCTTGTG TTTCCTCTTCCGGGTGAAGATAGTATTCAAAAGCAGAACTCGTGTGCTACGTCAAACGGACATGTGCAGGGGGAT GAAAGAAAAGAAGACACAAAGAAAGACACCACATCCTCGAATTGCGTAACAAACCAGAACGAAGGGGGTATTCCA TGTGAATGTGGTCAAAGTCCAGAATTCGAATCAGGAAAATGCGTCGTGCACGCCGAGGTAGGCTTGAAAACCGGG GAATCGAGAAAGCTCTCCCTTTCTGGCGAACAGCTCGATCAGAGCCACCAGCCACAGGTACCGGCCGCTTTCCTT CCAAAAGAAGATCCTGGGCAATCATCAGAAGCGTCCAAATCTCCTGTCAAAGAACTCTTCTCGATCTCACCACCC ACAAAATCCCCTACCGACCAGCCCCAACCCCCTCAACCCAGCGTCTCTCCCACGATGGACTGGAACCTCCACGTC CTCGTCGCGGAAGACGACCCAATCAATAGCACCATCATGCAAAAGCGCCTTGAGAAATTCGGCCACACAGTGCAC ATGACAAGCAACGGCAAAGAATGCCTATCTGCCTATAAAGCTGATCCCACCCACTTTGACGCAGTGCTGATGGAT CTACAAATGCCCATCGTCGATGGCCTTGGTGCAACACAGATGATACGCGAATACGAGCAAGAGCTGGCTAATGGA GACACGCCTGCGCCTCGCATTCCCATTTTTGCTGTCTCGGCTTCCTTGCTCGAGGAGAATCGGAAGATGTACATG GATTCGGGCTTTGATGGATGGGTCATGAAGCCCATTGATTTCCACAGGGTTGATCGGTTGCTTGGGGGTGTTAGG CTTCAGTGGGTACGTCAGGAGGTTGTTTACCGGCCTGGTGTGTGGGAGGCTGGAGGGTGGTTTGAGGCATAG
Gene	>Pro_DTO377G3_2|g6593.t1 ATGTCTGACAACAAGACTGAAGTATCGACGGTAGCCGAGCTGCTATCCCCGAAGTTGAAATTGCCTCAACTGGGC ACCGAATCGGCGGAAAGAGTCTTTCCTGTTCGTTCCGTCGTCTCATTTGATTCCACACCTTCATCCGCCCTGCAG ACACCTTCCCTCGATAAGCTCGAAACACCGATATCTCCTTTTTCGGACACATGGAGTGCAGGCTTCAGCAATGAA CAAGCGGGCTCTCAGCAGAAAAGTCCACCTGGGAAGAGTACGAATGCTGAGGATGGTGTCTCAAAGAGATCCGAC CATCCCACTCAACCGCGTGCTGAGAATGAAATTCCATCGGTACTCAAAGGACAACCTTGCTCCAGCCATAATCTT GACATTTTGGCACAATTGAAAACCACTGTGCAAAACGGTGGCGAAATCCTTGACATCCACAAATCAACAAAGGGG ATATGCTACTCGCATGAAGATGAAGAGAACATCTTCACTCAGTCATTCGGCGCACTGGTTGTGATAAAAGAGTCC GACGGTAACTTTGAAGTGCATATAGCAAGTGAAAACTCCAAGGAAATCATACAGCATTCTCCTGATCAACTCTTC GGGCTTCGAACATTTTGTGATATATTGCCATCATCGCAACACAGCAACTTTCTTGCTCATTCTAAATTCGTTTTG AGCGACGACTACTCAGTCCAGGACTCTGGTCCTGAGGTCTTCTTCCTTTGTGTATTGTCACCTGACGGATATATT CAGGGTACTTGGTGTACCATGCATACGAGCACAGTATATAAAGACTATATCATTTGCGAGCTTCAGCCCGAGCCT CGAGGGACAAAGGTTCAGCCCGATTTGGAGAACCCCGAAATTCAAACGACAAAAGCGGATAGCCAGACCTTGGAC ATGACCTCTGGAGCATTTCCTGAGAATATCAATCCTCCGGGAAAAGACCTTGATACCAGAAATAGCAAATTTCCC GACCCATCGGAGCTTCTCAATACCATCCCTCGAATCCTCCAGCGATTTGCAACTGCTCAAACGCTAGAAGCGCTC GTTCAAAATACCATCGCCACTCTGCAGAATATCATTGAATTTGACAGAACTACCATGTATCATTTCGATATTGAC CGCAACGGAATTGTGGTCGCCGATGCAGTTGATGGTTCGTCGGGGTTAACTTCGTACGAAGGCGTGCATTTCCCG GAATCAACCTTCCCCGAAGGATTGAAGAAACTATACACACGCAATACTGTATGCTGCTCTTGTTCTAGAAGCCAG GGCAGTTCAAAACTTGTGTATCGGGCTTCCACCAACAAAAGGCCCCTCGACATGTCAAACACCTATATCCATGCA GCACCGGCGCCCTTAACGCCGCATACCGAGAATCCCGTCAGGGCCTGTTTGTCAATCCAAATCAATGTCTTTGGT AAGCTTTGGGGTCTCATATCATGTCAGTCCTACGACAGTGGCCAAATGCTCCATCCGCTCATCCAGAAAGTGTGC TGGTTTGTAGCCGAGGCGGTTTCAAGTAACATTGAGCGTCTGTCCTACACCTTACCCTTTCAATTTCGAGAGCCG GACATCTCTTTGGATAAAACGCGCACATCTCAGGCTATAAAGACCCCACCCGGTGATCTTCTCAGTCTGTTCGGG GCAGATTACGCTGCAGCGTCGATCATGGGCGAGGCCAAAATCTTGGGGAAACCAATCGACTCGCAGGAAGTTTTG GCATTGTTCGAATACATGAAAGCCAAAGAAAATGACACGGTGTTTTGGTCTGCAGATATCGCTGCCGATTTTCGG GATCTCAATTACTCGCCCGGCTTTCATCATCTTTCTGGTTTGCTTTACGTTCCTCTTTCCATTGATGGTCGTGAT TTTATCATCTTTTTTCGGGCTGATTTAGAGAGCCATAACCTTGCTTCTAATTCAAGCCGGCAACATGAATGGTCG TCGGCAGAGTTTGGAAAGGCATCTGTACTGTCTTTGCTCTATCGCACTTTCACCGATATATGGCAAGAGAAGGAG GTTACACTGCAGAACAACCAGTTGATGAGGCTTTTACTGGCTAATTCGGCGCACGAGTTCAGAACACCTCTAAAT GCGATCATCAACTACCTGGAGATTGTTCTCGATGGTTCTCTAGATCAAGAAACACGAGATCATATTTCCAGATCT CACTCGGCTTCTAAGTCGTTGGTATACATCATCAATGACCTTCTAGATCTCACGAATACGGAAAACGGGCAAAAG TTGATAAAGGACGAGGTATTAGATCTCTCCGAGACCCTCACGGAAGCAACAGACATATTCTGGGAAGAAGCAAGA CAGAAGCATGTCGATCTACAAGTAGTCCAACACGCAGCCCTACCTCCCGTCCTCGGAGATCAACGGCGGGTACGC CAGGTGATCACAAACTTGATCAGTAATGCTATACAGCACACATCTACCGGAGCAGTGACAATCGAGTCTTGTGTT GTTCCGGAGCCGCTGGAGACAGATCATATCTGTGTCGAAGTCGCAATACATGATACCGGGTCTGGCATGTCCCAA CAGACTGTCGAAACATTGTTCTGCGAGCTGGAACAAGTATCCAACAAGGGATATATGCAGAATCCCAACTCATTT GAACATACTTCAAGTGGCCGTGTATTCGAGACGGAAAGCGTGCTTGGCCTGGGCCTCGCACTGGTCGCCCGAATC GTGCGCAATATGAACGGTCAGCTAAGCTTGAAGTCTGAAGAAGGCAAGGGAAGTTGCTTCAAGATCAGGCTTGTG TTTCCTCTTCCGGGTGAAGATAGTATTCAAAAGCAGAACTCGTGTGCTACGTCAAACGGACATGTGCAGGGGGAT GAAAGAAAAGAAGACACAAAGAAAGACACCACATCCTCGAATTGCGTAACAAACCAGAACGAAGGGGGTATTCCA TGTGAATGTGGTCAAAGTCCAGAATTCGAATCAGGAAAATGCGTCGTGCACGCCGAGGTAGGCTTGAAAACCGGG GAATCGAGAAAGCTCTCCCTTTCTGGCGAACAGCTCGATCAGAGCCACCAGCCACAGGTACCGGCCGCTTTCCTT CCAAAAGAAGATCCTGGGCAATCATCAGAAGCGTCCAAATCTCCTGTCAAAGAACTCTTCTCGATCTCACCACCC ACAAAATCCCCTACCGACCAGCCCCAACCCCCTCAACCCAGCGTCTCTCCCACGATGGACTGGAACCTCCACGTC CTCGTCGCGGAAGACGACCCAATCAATAGCACCATCATGCAAAAGCGCCTTGAGAAATTCGGCCACACAGTGCAC ATGACAAGCAACGGCAAAGAATGCCTATCTGCCTATAAAGCTGATCCCACCCACTTTGACGCAGTGCTGATGGAT CTACAAGTATGTCAACCAAGAATTAAACAAATTCCACCTCAATGCACATACTGACACTCAATTTCTTACGGCAGA TGCCCATCGTCGATGGCCTTGGTGCAACACAGATGATACGCGAATACGAGCAAGAGCTGGCTAATGGAGACACGC CTGCGCCTCGCATTCCCATTTTTGCTGTCTCGGCTTCCTTGCTCGAGGAGAATCGGAAGATGTACATGGATTCGG GCTTTGATGGATGGGTCATGAAGCCCATTGATTTCCACAGGGTTGATCGGTTGCTTGGGGGTGTTAGGCTTCAGT GGGTACGTCAGGAGGTTGTTTACCGGCCTGGTGTGTGGGAGGCTGGAGGGTGGTTTGAGGCATAG