Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g6564.t1
Gene name
Location	scaffold_17:526553..531952
Strand	+
Gene length (bp)	5399
Transcript length (bp)	3681
Coding sequence length (bp)	3681
Protein length (aa)	1227

Your browser does not support drawing a protein figure.

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF04424	MINDY_DUB	MINDY deubiquitinase	9.0E-20	429	554
PF03442	CBM_X2	Carbohydrate binding domain X2	1.8E-16	1049	1118
PF00150	Cellulase	Cellulase (glycosyl hydrolase family 5)	3.1E-08	883	1035

GO

GO Term	Description	Terminal node
GO:0071704	organic substance metabolic process	Yes
GO:1990380	Lys48-specific deubiquitinase activity	Yes
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	Yes
GO:0004843	cysteine-type deubiquitinase activity	Yes
GO:0003824	catalytic activity	No
GO:0008233	peptidase activity	No
GO:0016798	hydrolase activity, acting on glycosyl bonds	No
GO:0008150	biological_process	No
GO:0008152	metabolic process	No
GO:0019783	ubiquitin-like protein peptidase activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0101005	deubiquitinase activity	No
GO:0003674	molecular_function	No
GO:0016787	hydrolase activity	No
GO:0008234	cysteine-type peptidase activity	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 37	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

Click here for more information

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g6564.t1 MGLRKQPPPRLENISKSNVRSDARSSKSPNSASFHRPIRLNRFPSGDPIYSPDLNTSPAFDLMPLEEAQRSPVGS PTSQPPSSWPDNNRRPEDGRSGQYNQYEGAYNEPANTNGHWVSPTLTAGQQLGAAENVWRSTTDGGRASTGELPV QLQSNNPFLKPRPAEHTQDLLDRNEWGRDSHATSNSDALSQSEGYIPMTARLSLLDEPEQESPWTEAPRPQSNSQ QRPVLGGHHLDDNSPWDSQQSAKVPVPQGVYLQGEQSNPYAPAVAVQPSGLSDWETYAGQQYKPPSNSGRLGSDA GINTPSVALSNRTSATSHELIDFGELSATGNSVGETRSPAASTAYSEPAANGARSLSEKQDFAAPVIQQLQQPQA SPILSPAEAARQKEQRSETYTIRHIRWTDQSGQLLESPILVQNQNGPCPLLALINALVLRANPNAHPPIVRALST REQISLGLLIEAMFEELTTCLGPDEEFPDIEALTQFLTMLHTGMNVNPRLTMNSTEGFGTFLETSDLGLYSTFGI PLIHGWLASWSSPTHAAMSRTAQYYEDIQMLPFRRHEFEERVARGEALEPAEENIMADIQTIQRFVEIENATQLS PFGLTQLSTKLTPGSVSILFRNDHFSTLYKHPQSHQLYTLVTDAGYAGHAEVVWESLVDVTGFNTEYYSGDFRPV GAGPSAPSGPDPAVLQASNEPATHSPEANEGSKSPELTQEQSDADYAYALSLQFQEEERRENARNEQARDRRTSA PSNSSNRPLPSPRLSNVPNRPLPSPRLSNVPNRSSSIANTIGSRPSPQPQHGPDPEDPNAPPPPYEQAAASGPRC SPPDIRPYGRAAGNQYPGNRNPRNRTSQSSHRPRPPRVSNVVDMIVARGIYAIVDVHHVAFEPINEPPCNTAVDV TESNKLNNIFLQAINDAGGFNSQRIVNLVGGGEDSVKTADWFVAPSGFWNPYAIQFHYYSPRERPFGARGSDSDK TTVQSDFQLLRNAFPDVPLLLGEYDASPTNTEPAARYKYLDFLIKTAASLDISCVLWNNGLDHLDRTAGVWRDSQ TLPFIFNGNTLSSISDSTCSALSLGTDYSVSGANIIFTASYLSKHLSSTTTPGINATLTLRFSGGDSSPAVQIVQ WKAPTLSSTSAVASTVSGSALSIPITWGGLSTVAALKALTKSGTYLVDDWTVSLSPIQQARVTYSNQYNWDDSNV ILTSSAISCHLCWPIDRVHLRVFPTG*
Coding	>Pro_DTO377G3_2|g6564.t1 ATGGGCCTGCGAAAACAGCCCCCACCGCGTCTGGAGAACATTAGCAAGTCAAATGTTCGATCGGACGCACGCTCA TCCAAGTCACCCAACTCTGCTTCCTTCCATCGCCCGATTCGTTTAAACCGATTTCCTTCTGGGGACCCTATCTAC TCTCCCGACCTCAATACTTCACCTGCGTTTGACCTGATGCCACTTGAGGAAGCACAGCGGTCGCCTGTGGGGTCT CCCACCAGCCAACCCCCGAGCTCATGGCCAGACAATAACAGAAGACCGGAAGACGGCCGCTCCGGTCAGTATAAT CAGTATGAGGGAGCATACAACGAACCTGCAAATACCAACGGACACTGGGTTTCCCCGACATTGACGGCAGGTCAA CAACTAGGAGCGGCCGAGAATGTGTGGCGGTCAACGACTGATGGCGGTCGTGCTTCGACTGGAGAGCTACCGGTA CAGCTGCAGTCGAATAACCCATTCTTGAAGCCTAGGCCGGCAGAGCATACTCAAGATCTCTTGGATCGCAATGAG TGGGGACGTGATTCACATGCGACTTCAAACAGTGACGCATTGAGCCAATCCGAAGGGTATATTCCGATGACTGCG CGGCTCTCTCTTTTAGATGAGCCCGAACAAGAATCCCCATGGACCGAGGCTCCTCGTCCTCAATCCAATTCCCAG CAACGCCCTGTATTAGGCGGTCACCACCTCGATGATAACTCACCGTGGGACTCTCAACAGTCCGCCAAGGTTCCG GTTCCCCAGGGTGTCTACCTACAAGGAGAGCAGTCTAATCCATATGCCCCAGCGGTTGCGGTGCAGCCGTCTGGC CTTTCTGATTGGGAAACCTATGCCGGCCAACAATATAAGCCTCCATCCAATTCAGGGAGACTTGGATCGGATGCT GGAATCAATACTCCATCTGTTGCTCTTTCTAATCGAACCTCTGCTACCTCTCATGAACTAATTGATTTTGGTGAA TTGAGCGCCACTGGGAATTCGGTGGGCGAGACCAGGTCTCCTGCTGCATCTACGGCGTACTCAGAACCTGCCGCG AACGGAGCAAGATCATTATCAGAAAAGCAAGACTTCGCAGCTCCCGTGATACAACAACTACAACAACCCCAAGCA AGCCCTATACTGTCTCCCGCAGAAGCTGCACGACAAAAAGAGCAAAGATCAGAAACATATACTATTCGACACATC CGATGGACCGATCAGAGTGGTCAACTGCTGGAGTCCCCGATTTTGGTCCAAAATCAAAACGGACCTTGTCCTCTG CTAGCCCTTATAAATGCATTAGTGCTACGAGCGAACCCTAACGCTCACCCACCAATCGTTAGAGCTCTGTCAACT CGCGAGCAAATCTCTCTAGGTTTGCTAATCGAGGCGATGTTTGAAGAGCTGACAACATGCCTGGGCCCTGATGAG GAGTTCCCAGACATCGAGGCCCTCACTCAATTCCTGACAATGCTGCACACGGGTATGAATGTCAATCCACGTTTG ACAATGAATTCTACTGAAGGATTTGGCACTTTCCTCGAAACCAGCGACCTCGGACTGTATAGCACGTTTGGTATA CCATTGATCCATGGCTGGCTAGCCTCATGGTCCAGTCCTACCCATGCTGCGATGTCACGCACTGCCCAGTATTAC GAGGATATTCAAATGCTTCCCTTCCGCAGACACGAGTTTGAGGAACGGGTGGCGCGGGGCGAGGCACTTGAACCT GCGGAAGAGAATATCATGGCGGATATCCAAACCATCCAGCGATTTGTGGAAATTGAGAATGCGACACAATTGAGC CCATTTGGCCTGACACAGCTCTCAACTAAGCTTACGCCCGGATCTGTCTCCATTCTTTTCCGCAACGACCATTTC TCGACATTGTATAAACACCCGCAATCCCACCAACTCTACACTTTGGTTACCGATGCTGGCTATGCGGGCCATGCC GAGGTGGTTTGGGAATCTCTAGTCGATGTGACAGGATTCAACACAGAATATTACTCAGGCGATTTTCGACCTGTA GGCGCTGGTCCTTCAGCTCCATCTGGCCCTGATCCCGCGGTCCTCCAAGCCTCTAATGAGCCAGCCACTCATTCT CCAGAGGCAAACGAAGGATCGAAATCCCCTGAGCTGACTCAAGAACAGAGTGATGCCGACTATGCATACGCGCTG TCACTTCAGTTCCAAGAAGAAGAGCGACGCGAAAATGCTAGGAATGAGCAGGCTCGTGATCGTCGCACATCTGCG CCGAGTAATTCTTCCAATCGGCCATTGCCTTCGCCTCGCTTGAGCAATGTGCCTAATCGACCATTGCCCTCGCCT CGTTTGAGCAATGTACCCAATCGATCTTCGAGCATTGCCAATACGATTGGTTCTCGGCCTAGTCCTCAGCCACAA CATGGACCCGACCCTGAGGACCCAAATGCACCCCCTCCTCCATATGAACAAGCTGCTGCTAGCGGGCCGCGTTGT TCGCCTCCTGACATAAGGCCATATGGCCGTGCCGCAGGAAATCAGTACCCTGGTAACCGGAATCCGCGGAATCGA ACCTCGCAGTCTTCTCACCGACCACGCCCGCCTCGAGTCTCTAATGTGGTTGATATGATTGTGGCTCGTGGAATC TACGCTATCGTTGATGTGCATCATGTTGCCTTTGAGCCTATCAATGAGCCTCCTTGCAATACTGCGGTCGACGTT ACCGAGTCCAACAAACTGAACAACATCTTTCTCCAGGCTATCAATGATGCTGGTGGGTTCAACTCGCAGAGAATT GTTAATCTAGTCGGAGGTGGTGAGGATAGCGTCAAGACTGCAGACTGGTTTGTAGCACCCTCTGGATTTTGGAAT CCATATGCTATTCAGTTCCACTACTACAGTCCCCGGGAAAGACCATTTGGGGCTCGGGGCTCTGACAGTGACAAG ACTACTGTGCAGTCTGACTTCCAGCTGCTGCGCAACGCTTTCCCTGATGTACCTCTCCTTTTGGGTGAATACGAT GCTTCACCCACCAACACCGAACCCGCTGCCCGATATAAGTACCTTGACTTCTTGATCAAGACTGCAGCCAGTCTC GATATCTCCTGCGTGTTGTGGAATAACGGATTGGACCACTTGGATCGAACCGCAGGAGTCTGGCGTGACTCACAA ACTCTTCCATTCATCTTCAACGGTAACACCCTCTCGTCAATCAGTGACTCCACTTGCTCGGCATTGTCGTTGGGA ACAGACTATTCTGTTTCGGGTGCAAATATAATATTCACAGCTTCGTACTTATCCAAGCATCTTTCATCTACGACA ACACCGGGTATTAATGCCACTCTAACTCTGAGATTCTCGGGGGGCGATTCGTCCCCTGCTGTCCAAATTGTTCAA TGGAAAGCCCCAACTCTGTCGTCCACATCGGCGGTGGCTTCGACTGTCTCTGGCTCTGCCCTATCAATTCCAATC ACATGGGGCGGACTATCAACCGTCGCTGCATTAAAGGCCTTGACCAAGAGTGGAACATACCTGGTCGATGACTGG ACGGTATCACTGAGCCCTATCCAGCAAGCGAGAGTTACCTACAGCAACCAGTATAACTGGGATGACTCCAATGTA ATCCTCACTTCATCTGCTATTAGCTGTCATCTCTGCTGGCCAATCGACCGTGTTCACCTTCGAGTTTTTCCCACG GGATAA
Transcript	>Pro_DTO377G3_2|g6564.t1 ATGGGCCTGCGAAAACAGCCCCCACCGCGTCTGGAGAACATTAGCAAGTCAAATGTTCGATCGGACGCACGCTCA TCCAAGTCACCCAACTCTGCTTCCTTCCATCGCCCGATTCGTTTAAACCGATTTCCTTCTGGGGACCCTATCTAC TCTCCCGACCTCAATACTTCACCTGCGTTTGACCTGATGCCACTTGAGGAAGCACAGCGGTCGCCTGTGGGGTCT CCCACCAGCCAACCCCCGAGCTCATGGCCAGACAATAACAGAAGACCGGAAGACGGCCGCTCCGGTCAGTATAAT CAGTATGAGGGAGCATACAACGAACCTGCAAATACCAACGGACACTGGGTTTCCCCGACATTGACGGCAGGTCAA CAACTAGGAGCGGCCGAGAATGTGTGGCGGTCAACGACTGATGGCGGTCGTGCTTCGACTGGAGAGCTACCGGTA CAGCTGCAGTCGAATAACCCATTCTTGAAGCCTAGGCCGGCAGAGCATACTCAAGATCTCTTGGATCGCAATGAG TGGGGACGTGATTCACATGCGACTTCAAACAGTGACGCATTGAGCCAATCCGAAGGGTATATTCCGATGACTGCG CGGCTCTCTCTTTTAGATGAGCCCGAACAAGAATCCCCATGGACCGAGGCTCCTCGTCCTCAATCCAATTCCCAG CAACGCCCTGTATTAGGCGGTCACCACCTCGATGATAACTCACCGTGGGACTCTCAACAGTCCGCCAAGGTTCCG GTTCCCCAGGGTGTCTACCTACAAGGAGAGCAGTCTAATCCATATGCCCCAGCGGTTGCGGTGCAGCCGTCTGGC CTTTCTGATTGGGAAACCTATGCCGGCCAACAATATAAGCCTCCATCCAATTCAGGGAGACTTGGATCGGATGCT GGAATCAATACTCCATCTGTTGCTCTTTCTAATCGAACCTCTGCTACCTCTCATGAACTAATTGATTTTGGTGAA TTGAGCGCCACTGGGAATTCGGTGGGCGAGACCAGGTCTCCTGCTGCATCTACGGCGTACTCAGAACCTGCCGCG AACGGAGCAAGATCATTATCAGAAAAGCAAGACTTCGCAGCTCCCGTGATACAACAACTACAACAACCCCAAGCA AGCCCTATACTGTCTCCCGCAGAAGCTGCACGACAAAAAGAGCAAAGATCAGAAACATATACTATTCGACACATC CGATGGACCGATCAGAGTGGTCAACTGCTGGAGTCCCCGATTTTGGTCCAAAATCAAAACGGACCTTGTCCTCTG CTAGCCCTTATAAATGCATTAGTGCTACGAGCGAACCCTAACGCTCACCCACCAATCGTTAGAGCTCTGTCAACT CGCGAGCAAATCTCTCTAGGTTTGCTAATCGAGGCGATGTTTGAAGAGCTGACAACATGCCTGGGCCCTGATGAG GAGTTCCCAGACATCGAGGCCCTCACTCAATTCCTGACAATGCTGCACACGGGTATGAATGTCAATCCACGTTTG ACAATGAATTCTACTGAAGGATTTGGCACTTTCCTCGAAACCAGCGACCTCGGACTGTATAGCACGTTTGGTATA CCATTGATCCATGGCTGGCTAGCCTCATGGTCCAGTCCTACCCATGCTGCGATGTCACGCACTGCCCAGTATTAC GAGGATATTCAAATGCTTCCCTTCCGCAGACACGAGTTTGAGGAACGGGTGGCGCGGGGCGAGGCACTTGAACCT GCGGAAGAGAATATCATGGCGGATATCCAAACCATCCAGCGATTTGTGGAAATTGAGAATGCGACACAATTGAGC CCATTTGGCCTGACACAGCTCTCAACTAAGCTTACGCCCGGATCTGTCTCCATTCTTTTCCGCAACGACCATTTC TCGACATTGTATAAACACCCGCAATCCCACCAACTCTACACTTTGGTTACCGATGCTGGCTATGCGGGCCATGCC GAGGTGGTTTGGGAATCTCTAGTCGATGTGACAGGATTCAACACAGAATATTACTCAGGCGATTTTCGACCTGTA GGCGCTGGTCCTTCAGCTCCATCTGGCCCTGATCCCGCGGTCCTCCAAGCCTCTAATGAGCCAGCCACTCATTCT CCAGAGGCAAACGAAGGATCGAAATCCCCTGAGCTGACTCAAGAACAGAGTGATGCCGACTATGCATACGCGCTG TCACTTCAGTTCCAAGAAGAAGAGCGACGCGAAAATGCTAGGAATGAGCAGGCTCGTGATCGTCGCACATCTGCG CCGAGTAATTCTTCCAATCGGCCATTGCCTTCGCCTCGCTTGAGCAATGTGCCTAATCGACCATTGCCCTCGCCT CGTTTGAGCAATGTACCCAATCGATCTTCGAGCATTGCCAATACGATTGGTTCTCGGCCTAGTCCTCAGCCACAA CATGGACCCGACCCTGAGGACCCAAATGCACCCCCTCCTCCATATGAACAAGCTGCTGCTAGCGGGCCGCGTTGT TCGCCTCCTGACATAAGGCCATATGGCCGTGCCGCAGGAAATCAGTACCCTGGTAACCGGAATCCGCGGAATCGA ACCTCGCAGTCTTCTCACCGACCACGCCCGCCTCGAGTCTCTAATGTGGTTGATATGATTGTGGCTCGTGGAATC TACGCTATCGTTGATGTGCATCATGTTGCCTTTGAGCCTATCAATGAGCCTCCTTGCAATACTGCGGTCGACGTT ACCGAGTCCAACAAACTGAACAACATCTTTCTCCAGGCTATCAATGATGCTGGTGGGTTCAACTCGCAGAGAATT GTTAATCTAGTCGGAGGTGGTGAGGATAGCGTCAAGACTGCAGACTGGTTTGTAGCACCCTCTGGATTTTGGAAT CCATATGCTATTCAGTTCCACTACTACAGTCCCCGGGAAAGACCATTTGGGGCTCGGGGCTCTGACAGTGACAAG ACTACTGTGCAGTCTGACTTCCAGCTGCTGCGCAACGCTTTCCCTGATGTACCTCTCCTTTTGGGTGAATACGAT GCTTCACCCACCAACACCGAACCCGCTGCCCGATATAAGTACCTTGACTTCTTGATCAAGACTGCAGCCAGTCTC GATATCTCCTGCGTGTTGTGGAATAACGGATTGGACCACTTGGATCGAACCGCAGGAGTCTGGCGTGACTCACAA ACTCTTCCATTCATCTTCAACGGTAACACCCTCTCGTCAATCAGTGACTCCACTTGCTCGGCATTGTCGTTGGGA ACAGACTATTCTGTTTCGGGTGCAAATATAATATTCACAGCTTCGTACTTATCCAAGCATCTTTCATCTACGACA ACACCGGGTATTAATGCCACTCTAACTCTGAGATTCTCGGGGGGCGATTCGTCCCCTGCTGTCCAAATTGTTCAA TGGAAAGCCCCAACTCTGTCGTCCACATCGGCGGTGGCTTCGACTGTCTCTGGCTCTGCCCTATCAATTCCAATC ACATGGGGCGGACTATCAACCGTCGCTGCATTAAAGGCCTTGACCAAGAGTGGAACATACCTGGTCGATGACTGG ACGGTATCACTGAGCCCTATCCAGCAAGCGAGAGTTACCTACAGCAACCAGTATAACTGGGATGACTCCAATGTA ATCCTCACTTCATCTGCTATTAGCTGTCATCTCTGCTGGCCAATCGACCGTGTTCACCTTCGAGTTTTTCCCACG GGATAA
Gene	>Pro_DTO377G3_2|g6564.t1 ATGGGCCTGCGAAAACAGCCCCCACCGCGTCTGGAGAACATTAGCAAGTCAAATGTTCGATCGGACGCACGCTCA TCCAAGTCACCCAACTCTGCTTCCTTCCATCGCCCGATTCGTTTAAACCGATTTCCTTCTGGGGACCCTATCTAC TCTCCCGACCTCAATACTTCACCTGCGTTTGACCTGATGCCACTTGAGGAAGCACAGCGGTCGCCTGTGGGGTCT CCCACCAGCCAACCCCCGAGCTCATGGCCAGACAATAACAGAAGACCGGAAGACGGCCGCTCCGGTCAGTATAAT CAGTATGAGGGAGCATACAACGAACCTGCAAATACCAACGGACACTGGGTTTCCCCGACATTGACGGCAGGTCAA CAACTAGGAGCGGCCGAGAATGTGTGGCGGTCAACGACTGATGGCGGTCGTGCTTCGACTGGAGAGCTACCGGTA CAGCTGCAGTCGAATAACCCATTCTTGAAGCCTAGGCCGGCAGAGCATACTCAAGATCTCTTGGATCGCAATGAG TGGGGACGTGATTCACATGCGACTTCAAACAGTGACGCATTGAGCCAATGTATGGCATTAGTTCCTTCTGAAAGT TCCCTCAAAATGATATTTGTTGCTAACAACTTGTAGCCGAAGGGTATATTCCGATGACTGCGCGGCTCTCTCTTT TAGATGAGCCCGAACAAGAATCCCCATGGACCGAGGCTCCTCGTCCTCAATCCAATTCCCAGCAACGCCCTGTAT TAGGCGGTCACCACCTCGATGATAACTCACCGTGGGACTCTCAACAGTCCGCCAAGGTTCCGGTTCCCCAGGGTG TCTACCTACAAGGAGAGCAGTCTAATCCATATGCCCCAGCGGTTGCGGTGCAGCCGTCTGGCCTTTCTGATTGGG AAACCTATGCCGGCCAACAATATAAGCCTCCATCCAATTCAGGGAGACTTGGATCGGATGCTGGAATCAATACTC CATCTGTTGCTCTTTCTAATCGAACCTCTGCTACCTCTCATGAACTAATTGATTTTGGTGAATTGAGCGCCACTG GGAATTCGGTGGGCGAGACCAGGTCTCCTGCTGCATCTACGGCGTACTCAGAACCTGCCGCGAACGGAGCAAGAT CATTATCAGAAAAGCAAGACTTCGCAGCTCCCGTGATACAACAACTACAACAACCCCAAGCAAGCCCTATACTGT CTCCCGCAGAAGCTGCACGACAAAAAGAGCAAAGATCAGAAACATATACTATTCGACACATCCGATGGACCGATC AGAGTGGTCAACTGCTGGAGTCCCCGATTTTGGTCCAAAATCAAAACGGACCTTGTCCTCTGCTAGCCCTTATAA ATGCATTAGTGCTACGAGCGAACCCTAACGCTCACCCACCAATCGTTAGAGCTCTGTCAACTCGCGAGCAAATCT CTCTAGGTTTGCTAATCGAGGCGATGTTTGAAGAGCTGACAACATGCCTGGGCCCTGATGAGGAGTTCCCAGACA TCGAGGCCCTCACTCAATTCCTGACAATGCTGCACACGGGTATGAATGTCAATCCACGTTTGACAATGGTGAGTA CATGCGATGTATCTGTCAAATATCACTTATACTAACCTAATGTCAGAATTCTACTGAAGGATTTGGCACTTTCCT CGAAACCAGCGACCTCGGACTGTATAGCACGTTTGGTATACCATTGATCCATGGCTGGCTAGCCTCATGGTCCAG TCCTACCCATGCTGCGATGTCACGCACTGCCCAGTATTACGAGGATATTCAAATGCTTCCCTTCCGCAGACACGA GTTTGAGGAACGGGTGGCGCGGGGCGAGGCACTTGAACCTGCGGAAGAGAATATCATGGCGGATATCCAAACCAT CCAGCGATTTGTGGAAATTGAGAATGCGACACAATTGAGCCCATTTGGCCTGACACAGCTCTCAACTAAGCTTAC GCCCGGATCTGTCTCCATTCTTTTCCGCAACGACCATTTCTCGACATTGTATAAACACCCGCAATCCCACCAACT CTACACTTTGGTTACCGATGCTGGCTATGCGGGCCATGCCGAGGTGGTTTGGGAATCTCTAGTCGATGTGACAGG ATTCAACACAGAATATTACTCAGGCGATTTTCGACCTGTAGGCGCTGGTCCTTCAGCTCCATCTGGCCCTGATCC CGCGGTCCTCCAAGCCTCTAATGAGCCAGCCACTCATTCTCCAGAGGCAAACGAAGGATCGAAATCCCCTGAGCT GACTCAAGAACAGAGTGATGCCGACTATGCATACGCGCTGTCACTTCAGTTCCAAGAAGAAGAGCGACGCGAAAA TGCTAGGAATGAGCAGGCTCGTGATCGTCGCACATCTGCGCCGAGTAATTCTTCCAATCGGCCATTGCCTTCGCC TCGCTTGAGCAATGTGCCTAATCGACCATTGCCCTCGCCTCGTTTGAGCAATGTACCCAATCGATCTTCGAGCAT TGCCAATACGATTGGTTCTCGGCCTAGTCCTCAGCCACAACATGGACCCGACCCTGAGGACCCAAATGCACCCCC TCCTCCATATGAACAAGCTGCTGCTAGCGGGCCGCGTTGTTCGCCTCCTGACATAAGGCCATATGGCCGTGCCGC AGGAAATCAGTACCCTGGTAACCGGAATCCGCGGAATCGAACCTCGCAGTCTTCTCACCGACCACGCCCGCCTGT ACGTGCAGGGGATCATAATATAGAAACAGAACGGAACAAAGAATGCATAGTGATGTGACCAATGTAAGATCTGGA AATGATAAGAGGCGTTGATACTTGCTTTACGCCAATGCACTGGATGGATGAATATGATGCCTACAAATGATATAT ACTATTGTAGAGAAAGAACATGTCTTTGATTGATTCGATTCCATATGGAACCTTAATTTCTTGCTCCTCGTTATC CTCATTCTCCACGGCGTTATGGAAATTAACAAGGACCTTCTCCGTGCCTCTAACAGGAGCGGGGCTAATAAGCAT ATATCAACAAAGTGACATGTGAGATAGCTACGTATGTTCGGACTTGTCACGGACTACACCTATGCCCGGAGGTTA AGTAAATTAAAGGACTCACATGAGGAAGAGGTTTCTCATTGGAGGAGTCATTATCCAGATAGCCCTAGATCTTCC CCCGGGAAAGACTAAAAAAGTGTGTATAAGCTATGTATTGCGATATATGCCGACCATATTGCCCTATAGCCTAAG TCAAAGGCGATTTGGGACGCTCTTATGTCCTGAATGATACAACCCCGGTCCACCGGCCCGTTGACTAGGATCAGG GCATACGTAGTATAAAGAATGCTGCTATGCTAAAATTGGCCTATAATCATCCTTCACGGTGCTGATTTCCTTGCG AGCCATCAGGATCTGTATATTTCCTCTGACAGTAGCTCTTGCGATGCAGATTCTTCTTTCTAGTGCTCTAGCCCT CGTTGGGATGGCCCAGGCCACTACTGTTTGCAGTGGAACATTTAGCACAATCTCAGCTGCCGAGTTTGTGTCTAA CCTGCGTCCCGGTTGGAATCTGGGAAATAATCTTGATGCTGTCCCCGATGAGGGATCTTGGAATAATATGCCAGT TGTGGCGTCGACAGTTGATACTATAAAGGATGCCGGCTTTAGGAGTGTCCGACTGCCAGTTACCTGGGCATATCA TTTCACCGGAGGCTCACCTAATTGGACTATTGACCCAGCATGATTACAGCGAGTCTCTAATGTGGTTGATATGAT TGTGGCTCGTGGAATCTACGCTATCGTTGATGTGCATCATGGTATGATATATGATCTTGTATCGGAGAAGGGCCT TTACTGATATAAAACAGATTCATGGGTTTGGGCTGATGCTACCCAGTCTGGAACCAATCTTACTATGATTGAAGA AAAATTCTATCGTCTCTGGTATCAAATTGGAACGAAGTTGGCCTGACAATCCAACCTAGTTGCCTTTGAGCCTAT CAATGAGCCTCCTTGCAATACTGCGGTCGACGTTACCGAGTCCAACAAACTGAACAACATCTTTCTCCAGGCTAT CAATGATGCTGGTGGGTTCAACTCGCAGAGAATTGTTAATCTAGTCGGAGGTGGTGAGGATAGCGTCAAGACTGC AGACTGGTTTGTAGCACCCTCTGGATTTTGGAATCCATATGCTATTCAGTTCCACTACTACAGTCCCCGTGGGCC ATAGATCAGTTTATACTTCAGGTATAATGCGTTGTGGGTTGAACTGGCCGAGTGGGCTTCTAGACGACTTGATAT TCAGCGCTTGGTAAGAGTATAGACCCAGTTTTTTTTTTTTTTTTTTTTTTTAATTTTTTTATTTTTTTTTTTTTT TTTATTTTTTTTTTTTTTTTTTTTTTTTTTTTCATTGTTTACTGATTTCAAACAGGGGAAAGACCATTTGGGGCT CGGGGCTCTGACAGTGACAAGACTACTGTGCAGTCTGACTTCCAGCTGCTGCGCAACGCTTTCCCTGATGTACCT CTCCTTTTGGGTGAATACGATGCTTCACCCACCAACACCGAACCCGCTGCCCGATATAAGTACCTTGACTTCTTG ATCAAGACTGCAGCCAGTCTCGATATCTCCTGCGTGTTGTGGAATAACGGATTGGACCACTTGGATCGAACCGCA GGAGTCTGGCGTGACTGTAACTCACTCTCGATCATCACAAAATCAACCGAGTCTACTGCCAATAGTTTACCAGAT AGTACCGAGGACGCTTCTGCAACCACACATTCATAATCAGCTTATATTTTCCATCAGTATGGAACAGTTGTGACA GCACAAACTCTTCCATTCATCTTCAACGGTAACACCCTCTCGTCAATCAGTGACTCCACTTGCTCGGCATTGTCG TTGGGAACAGACTATTCTGTTTCGGGTGCAAATATAATATTCACAGCTTCGTACTTATCCAAGCATCTTTCATCT ACGACAACACCGGGTATTAATGCCACTCTAACTCTGAGATTCTCGGGGGGCGATTCGTCCCCTGCTGTCCAAATT GTTCAATGGAAAGCCCCAACTCTGTCGTCCACATCGGCGGTGGCTTCGACTGTCTCTGGCTCTGCCCTATCAATT CCAATCACATGGGGCGGACTATCAACCGTCGCTGCATTAAAGGCCTTGACCAAGAGTGGAACATACCTGGTCGAT GACTGGACGGTATCACTGAGCCCTATCCAGCAAGCGAGAGTTGTAAGCCAAGCCCTATTTCTCTTTGTGTACCAT TTACTAATACTACTAATATATCGATCTAGACCTACAGCAACCAGTATAACTGGGATGACTCCAATGTAATCCTCA CTTCATCTGCTATTAGCTGTCATCTCTGCTGGCCAATCGACCGTGTTCACCTTCGAGTTTTTCCCACGGGATAA