Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g5886.t1
Gene name
Location	scaffold_15:70680..74049
Strand	-
Gene length (bp)	3369
Transcript length (bp)	3369
Coding sequence length (bp)	3369
Protein length (aa)	1123

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF12796	Ank_2	Ankyrin repeats (3 copies)	3.8E-14	56	143
PF12796	Ank_2	Ankyrin repeats (3 copies)	1.4E-13	231	299
PF12796	Ank_2	Ankyrin repeats (3 copies)	3.7E-08	302	357
PF00023	Ank	Ankyrin repeat	1.9E-03	82	110
PF00023	Ank	Ankyrin repeat	3.4E-06	113	143
PF00023	Ank	Ankyrin repeat	3.4E-03	188	209
PF00023	Ank	Ankyrin repeat	4.9E-03	237	265
PF00023	Ank	Ankyrin repeat	3.2E-04	270	299
PF00023	Ank	Ankyrin repeat	7.0E-04	302	323
PF13857	Ank_5	Ankyrin repeats (many copies)	2.1E-09	99	150
PF13857	Ank_5	Ankyrin repeats (many copies)	1.7E-07	289	341
PF13637	Ank_4	Ankyrin repeats (many copies)	1.4E-09	82	133
PF13637	Ank_4	Ankyrin repeats (many copies)	2.5E-06	239	278
PF13637	Ank_4	Ankyrin repeats (many copies)	5.4E-12	271	323
PF13606	Ank_3	Ankyrin repeat	3.3E-03	188	211
PF13606	Ank_3	Ankyrin repeat	5.1E-04	270	298
PF13606	Ank_3	Ankyrin repeat	5.1E-03	302	325
PF01544	CorA	CorA-like Mg2+ transporter protein	3.6E-11	856	1018

GO

GO Term	Description	Terminal node
GO:0016020	membrane	Yes
GO:0055085	transmembrane transport	Yes
GO:0005515	protein binding	Yes
GO:0030001	metal ion transport	Yes
GO:0046873	metal ion transmembrane transporter activity	Yes
GO:0003674	molecular_function	No
GO:0006810	transport	No
GO:0008150	biological_process	No
GO:0005575	cellular_component	No
GO:0022857	transmembrane transporter activity	No
GO:0051234	establishment of localization	No
GO:0005488	binding	No
GO:0008324	cation transmembrane transporter activity	No
GO:0009987	cellular process	No
GO:0022890	inorganic cation transmembrane transporter activity	No
GO:0006812	cation transport	No
GO:0006811	ion transport	No
GO:0015075	ion transmembrane transporter activity	No
GO:0051179	localization	No
GO:0015318	inorganic molecular entity transmembrane transporter activity	No
GO:0005215	transporter activity	No
GO:0110165	cellular anatomical entity	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	967	989	22
2	1001	1023	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g5886.t1 MPASSITSDSHERLEPRLLRAAESNDIDSLKKTIALAHEYNQLNDNFLRIGLMRSAERACIAATEYLLTHGAKTD VPSNRASPLLRAVERDHYEIVRLLLDHGACPNSADKEGRTALMTAAWKNHADILHLLIMRGADVNQRDLRRRNAL HNLAADRACRWGWGEEVVGLLLRTECAIDGVAGQDELGRTPLHWACATGNWRMAEMLLTRNAGEGEKEGEVRGSG LGAQIDAVELRGKTALHVATAHDRADIVQLLIAHKAAVNAASDGGWTPLHNACDKGCEAIVRILLSEGAHINAQL LNGITPLHLAAQGGHREVVQCLLEKPDLKRRVRDNFGSTPFLRAAQFKRKDIVLLLAPFNNVDSLSDGVKEACAA FDATVVDFGNFHNENRVKRMSVFNLLYGRDPENPRKQAVTTVPVDSRGTDFRWIHLPANNMAWVEALLTKSFIEE GAHDVDGFKGLEKSFNYQHRGQRTHSHFMRPLCQNTPRTMLRRHEEETPEEPASENGQVRAMDSPARKQKGTGSK PEKADSYFHDEGHGKKNKNNPKRGKSGSVPGTPKQETKGKSGQGEKQRSSLSSSTFCKDPHPLVSACNVCVFMPY LHFETTERRQQMQDAISRAETLDFIPRGIKRTRTRDEILIYAHLSSSTTSLHVRRTLDQFFYPNIDTKSRDQDQV VYRYQTKSPGMGADPKIFMVDQLWMWVLGTNLIVTAFPQRWDQPKNDPLNVLDGIIEDINSKTRDPVKSVYDLAM IITNRCSGVFDRHRLGDEEYQFLDMFESSIGIATDKETVLFNQFNHASGQASEWLKSHRKLNGSFSSPPKSYNGT DEQDQSSNYCDEDGQPLFVDRLLDIGQETNLLAETKDIRDELNMIRTVLEHQNNVLLDFQEVVCETYQGQHRSQF EVKKRFKDQQRMIDMHLKDIDRMDKQAERIYHSITDLLDLKQKHANAFEARFARDQAAGTTRQSKTIMVFTIVTI VFLPLSFIASIFTINLKEFESLNLGYVAKYTFGIGFAISIPLVWVALTVDDIGGFFRVGSRRWLSNRAKVSAKSE RSEETLQALEMEKIMSLPRMRRSVDVEYGGGLLPVSTRGTGASRRPDLYGGLSNGTMRKSYDLRPSMDSRLR*
Coding	>Pro_DTO377G3_2|g5886.t1 ATGCCAGCCTCAAGCATAACAAGCGACAGCCACGAGCGCCTGGAGCCACGGCTCCTCCGCGCCGCCGAATCCAAC GACATCGACTCCCTAAAAAAGACAATAGCCCTCGCCCACGAGTACAACCAACTAAACGACAACTTCCTCCGCATC GGCCTAATGCGCAGCGCCGAACGAGCCTGCATCGCCGCAACAGAATACCTCCTCACGCACGGCGCCAAAACCGAC GTCCCCTCCAACCGCGCCTCACCCCTCCTCCGCGCCGTCGAGCGCGACCACTACGAAATCGTCCGTCTGCTGCTC GACCACGGCGCCTGTCCCAACTCCGCCGACAAAGAAGGCCGCACGGCGCTCATGACCGCGGCGTGGAAGAACCAC GCCGATATCCTGCACCTGCTTATCATGCGGGGCGCGGACGTGAACCAGCGCGATCTGCGCCGCCGGAACGCGTTG CATAACCTCGCCGCTGATAGGGCTTGTCGGTGGGGGTGGGGGGAGGAGGTTGTGGGGTTGTTGTTGCGGACGGAG TGTGCTATTGATGGGGTTGCGGGGCAGGATGAGCTGGGGCGGACGCCGTTGCATTGGGCTTGTGCGACGGGGAAT TGGAGGATGGCGGAGATGTTGTTGACGAGGAATGCTGGCGAGGGGGAGAAAGAGGGGGAGGTGCGGGGGTCCGGG CTGGGGGCGCAGATCGATGCCGTTGAGCTGCGTGGTAAGACGGCGTTGCATGTTGCTACGGCTCATGACCGTGCG GATATCGTGCAGCTGCTGATTGCGCACAAGGCGGCGGTTAATGCTGCTAGTGATGGTGGCTGGACGCCGCTTCAT AATGCCTGTGATAAGGGGTGTGAGGCGATTGTGCGGATTCTGCTGAGCGAAGGCGCGCATATCAACGCACAGCTT TTGAATGGCATTACGCCGCTGCATCTTGCTGCGCAGGGCGGCCATCGCGAGGTCGTGCAGTGTCTTCTTGAGAAG CCTGATCTGAAACGTCGGGTTAGGGATAATTTTGGCAGTACGCCGTTTCTGCGTGCGGCGCAGTTCAAGCGGAAG GATATTGTGCTGTTGCTGGCGCCGTTTAACAATGTCGACAGTCTATCTGATGGTGTCAAGGAGGCTTGTGCGGCG TTCGATGCTACTGTTGTTGACTTTGGAAACTTCCATAATGAGAATCGGGTTAAGCGCATGTCGGTATTTAATCTG CTTTATGGGAGGGATCCGGAGAATCCTAGGAAACAGGCTGTTACCACTGTGCCGGTTGATAGTCGTGGGACTGAT TTCCGGTGGATTCACTTACCGGCGAACAATATGGCGTGGGTGGAAGCTCTGCTTACCAAGTCCTTTATTGAGGAG GGCGCACATGATGTTGATGGGTTCAAGGGGCTGGAGAAGTCTTTCAACTATCAGCATCGGGGTCAAAGGACTCAT TCGCACTTTATGCGACCGTTGTGTCAGAATACGCCGCGGACGATGCTGCGTCGACATGAAGAGGAGACTCCGGAG GAGCCTGCGTCTGAGAATGGGCAGGTAAGGGCCATGGATAGCCCTGCCCGCAAGCAAAAAGGCACAGGCAGCAAG CCTGAAAAGGCGGATTCTTATTTTCACGACGAAGGGCATGGAAAAAAGAACAAGAACAATCCGAAGCGCGGCAAG TCGGGTAGCGTACCAGGGACTCCCAAGCAGGAGACGAAGGGGAAGTCGGGCCAGGGCGAGAAACAGAGGTCATCA CTGTCTTCATCAACCTTTTGCAAAGACCCTCACCCTCTGGTTTCTGCATGTAATGTCTGCGTGTTCATGCCGTAT CTACATTTCGAGACCACAGAGCGCAGACAACAGATGCAGGATGCAATCTCCCGAGCGGAAACGCTTGATTTTATA CCCAGGGGGATAAAGAGAACGCGCACAAGAGACGAAATACTCATATATGCGCATCTATCGTCCTCAACGACCTCC CTCCATGTCCGCCGAACACTGGACCAGTTTTTCTACCCGAATATCGATACCAAGAGTCGTGATCAGGACCAAGTT GTGTACCGGTACCAAACAAAAAGCCCCGGAATGGGGGCAGACCCCAAGATATTCATGGTGGATCAACTCTGGATG TGGGTTCTAGGCACGAATCTGATTGTAACGGCCTTCCCGCAGAGATGGGACCAGCCCAAGAATGACCCGCTTAAT GTGCTGGATGGGATTATCGAGGATATCAATTCCAAAACCCGCGACCCTGTCAAATCCGTCTATGATCTAGCCATG ATAATCACCAATCGATGCTCGGGTGTCTTCGATCGACACCGCCTAGGCGACGAGGAGTACCAGTTCCTAGATATG TTCGAGTCATCTATAGGTATAGCCACGGACAAAGAGACCGTGCTTTTTAACCAATTCAACCACGCCTCCGGGCAG GCATCAGAGTGGCTGAAAAGTCACCGCAAGCTGAACGGCTCCTTCAGCTCTCCGCCAAAGTCCTACAATGGGACC GACGAGCAAGATCAAAGCAGCAACTACTGCGACGAGGACGGCCAGCCACTATTCGTCGACCGACTCCTAGACATC GGACAGGAAACCAATCTCCTAGCGGAGACAAAGGACATCAGAGACGAGCTGAACATGATCCGGACGGTGCTGGAG CACCAGAACAACGTCCTGCTCGACTTCCAAGAAGTCGTCTGCGAGACCTATCAAGGCCAGCACCGGTCCCAATTC GAAGTCAAGAAACGGTTCAAAGACCAGCAGCGCATGATCGACATGCACCTAAAGGATATTGACCGCATGGATAAA CAAGCCGAGCGCATCTACCACTCCATCACGGACCTGCTCGATCTGAAACAGAAACACGCGAACGCGTTCGAGGCC CGCTTCGCCCGTGACCAGGCTGCCGGTACAACCCGCCAGAGTAAGACAATTATGGTCTTCACTATTGTCACTATT GTCTTCCTGCCGTTGTCGTTTATCGCCTCCATCTTCACGATCAACCTGAAAGAATTCGAGAGCTTGAATCTCGGC TATGTGGCAAAGTATACCTTTGGTATTGGCTTTGCAATCTCCATCCCGCTTGTCTGGGTCGCTCTCACCGTTGAT GATATCGGGGGTTTCTTCCGCGTGGGCAGTCGACGCTGGTTGTCTAACCGGGCGAAGGTGTCTGCGAAGAGTGAA CGAAGCGAGGAAACGCTCCAGGCTTTGGAGATGGAGAAAATTATGAGTTTACCGCGCATGAGGAGGAGTGTCGAT GTGGAATATGGTGGTGGTCTGCTACCTGTTTCTACACGCGGCACGGGGGCCTCGAGGCGGCCTGATCTATATGGT GGATTGAGCAATGGCACTATGCGGAAAAGTTACGACCTGCGGCCTAGTATGGACTCCAGATTACGATGA
Transcript	>Pro_DTO377G3_2|g5886.t1 ATGCCAGCCTCAAGCATAACAAGCGACAGCCACGAGCGCCTGGAGCCACGGCTCCTCCGCGCCGCCGAATCCAAC GACATCGACTCCCTAAAAAAGACAATAGCCCTCGCCCACGAGTACAACCAACTAAACGACAACTTCCTCCGCATC GGCCTAATGCGCAGCGCCGAACGAGCCTGCATCGCCGCAACAGAATACCTCCTCACGCACGGCGCCAAAACCGAC GTCCCCTCCAACCGCGCCTCACCCCTCCTCCGCGCCGTCGAGCGCGACCACTACGAAATCGTCCGTCTGCTGCTC GACCACGGCGCCTGTCCCAACTCCGCCGACAAAGAAGGCCGCACGGCGCTCATGACCGCGGCGTGGAAGAACCAC GCCGATATCCTGCACCTGCTTATCATGCGGGGCGCGGACGTGAACCAGCGCGATCTGCGCCGCCGGAACGCGTTG CATAACCTCGCCGCTGATAGGGCTTGTCGGTGGGGGTGGGGGGAGGAGGTTGTGGGGTTGTTGTTGCGGACGGAG TGTGCTATTGATGGGGTTGCGGGGCAGGATGAGCTGGGGCGGACGCCGTTGCATTGGGCTTGTGCGACGGGGAAT TGGAGGATGGCGGAGATGTTGTTGACGAGGAATGCTGGCGAGGGGGAGAAAGAGGGGGAGGTGCGGGGGTCCGGG CTGGGGGCGCAGATCGATGCCGTTGAGCTGCGTGGTAAGACGGCGTTGCATGTTGCTACGGCTCATGACCGTGCG GATATCGTGCAGCTGCTGATTGCGCACAAGGCGGCGGTTAATGCTGCTAGTGATGGTGGCTGGACGCCGCTTCAT AATGCCTGTGATAAGGGGTGTGAGGCGATTGTGCGGATTCTGCTGAGCGAAGGCGCGCATATCAACGCACAGCTT TTGAATGGCATTACGCCGCTGCATCTTGCTGCGCAGGGCGGCCATCGCGAGGTCGTGCAGTGTCTTCTTGAGAAG CCTGATCTGAAACGTCGGGTTAGGGATAATTTTGGCAGTACGCCGTTTCTGCGTGCGGCGCAGTTCAAGCGGAAG GATATTGTGCTGTTGCTGGCGCCGTTTAACAATGTCGACAGTCTATCTGATGGTGTCAAGGAGGCTTGTGCGGCG TTCGATGCTACTGTTGTTGACTTTGGAAACTTCCATAATGAGAATCGGGTTAAGCGCATGTCGGTATTTAATCTG CTTTATGGGAGGGATCCGGAGAATCCTAGGAAACAGGCTGTTACCACTGTGCCGGTTGATAGTCGTGGGACTGAT TTCCGGTGGATTCACTTACCGGCGAACAATATGGCGTGGGTGGAAGCTCTGCTTACCAAGTCCTTTATTGAGGAG GGCGCACATGATGTTGATGGGTTCAAGGGGCTGGAGAAGTCTTTCAACTATCAGCATCGGGGTCAAAGGACTCAT TCGCACTTTATGCGACCGTTGTGTCAGAATACGCCGCGGACGATGCTGCGTCGACATGAAGAGGAGACTCCGGAG GAGCCTGCGTCTGAGAATGGGCAGGTAAGGGCCATGGATAGCCCTGCCCGCAAGCAAAAAGGCACAGGCAGCAAG CCTGAAAAGGCGGATTCTTATTTTCACGACGAAGGGCATGGAAAAAAGAACAAGAACAATCCGAAGCGCGGCAAG TCGGGTAGCGTACCAGGGACTCCCAAGCAGGAGACGAAGGGGAAGTCGGGCCAGGGCGAGAAACAGAGGTCATCA CTGTCTTCATCAACCTTTTGCAAAGACCCTCACCCTCTGGTTTCTGCATGTAATGTCTGCGTGTTCATGCCGTAT CTACATTTCGAGACCACAGAGCGCAGACAACAGATGCAGGATGCAATCTCCCGAGCGGAAACGCTTGATTTTATA CCCAGGGGGATAAAGAGAACGCGCACAAGAGACGAAATACTCATATATGCGCATCTATCGTCCTCAACGACCTCC CTCCATGTCCGCCGAACACTGGACCAGTTTTTCTACCCGAATATCGATACCAAGAGTCGTGATCAGGACCAAGTT GTGTACCGGTACCAAACAAAAAGCCCCGGAATGGGGGCAGACCCCAAGATATTCATGGTGGATCAACTCTGGATG TGGGTTCTAGGCACGAATCTGATTGTAACGGCCTTCCCGCAGAGATGGGACCAGCCCAAGAATGACCCGCTTAAT GTGCTGGATGGGATTATCGAGGATATCAATTCCAAAACCCGCGACCCTGTCAAATCCGTCTATGATCTAGCCATG ATAATCACCAATCGATGCTCGGGTGTCTTCGATCGACACCGCCTAGGCGACGAGGAGTACCAGTTCCTAGATATG TTCGAGTCATCTATAGGTATAGCCACGGACAAAGAGACCGTGCTTTTTAACCAATTCAACCACGCCTCCGGGCAG GCATCAGAGTGGCTGAAAAGTCACCGCAAGCTGAACGGCTCCTTCAGCTCTCCGCCAAAGTCCTACAATGGGACC GACGAGCAAGATCAAAGCAGCAACTACTGCGACGAGGACGGCCAGCCACTATTCGTCGACCGACTCCTAGACATC GGACAGGAAACCAATCTCCTAGCGGAGACAAAGGACATCAGAGACGAGCTGAACATGATCCGGACGGTGCTGGAG CACCAGAACAACGTCCTGCTCGACTTCCAAGAAGTCGTCTGCGAGACCTATCAAGGCCAGCACCGGTCCCAATTC GAAGTCAAGAAACGGTTCAAAGACCAGCAGCGCATGATCGACATGCACCTAAAGGATATTGACCGCATGGATAAA CAAGCCGAGCGCATCTACCACTCCATCACGGACCTGCTCGATCTGAAACAGAAACACGCGAACGCGTTCGAGGCC CGCTTCGCCCGTGACCAGGCTGCCGGTACAACCCGCCAGAGTAAGACAATTATGGTCTTCACTATTGTCACTATT GTCTTCCTGCCGTTGTCGTTTATCGCCTCCATCTTCACGATCAACCTGAAAGAATTCGAGAGCTTGAATCTCGGC TATGTGGCAAAGTATACCTTTGGTATTGGCTTTGCAATCTCCATCCCGCTTGTCTGGGTCGCTCTCACCGTTGAT GATATCGGGGGTTTCTTCCGCGTGGGCAGTCGACGCTGGTTGTCTAACCGGGCGAAGGTGTCTGCGAAGAGTGAA CGAAGCGAGGAAACGCTCCAGGCTTTGGAGATGGAGAAAATTATGAGTTTACCGCGCATGAGGAGGAGTGTCGAT GTGGAATATGGTGGTGGTCTGCTACCTGTTTCTACACGCGGCACGGGGGCCTCGAGGCGGCCTGATCTATATGGT GGATTGAGCAATGGCACTATGCGGAAAAGTTACGACCTGCGGCCTAGTATGGACTCCAGATTACGATGA
Gene	>Pro_DTO377G3_2|g5886.t1 ATGCCAGCCTCAAGCATAACAAGCGACAGCCACGAGCGCCTGGAGCCACGGCTCCTCCGCGCCGCCGAATCCAAC GACATCGACTCCCTAAAAAAGACAATAGCCCTCGCCCACGAGTACAACCAACTAAACGACAACTTCCTCCGCATC GGCCTAATGCGCAGCGCCGAACGAGCCTGCATCGCCGCAACAGAATACCTCCTCACGCACGGCGCCAAAACCGAC GTCCCCTCCAACCGCGCCTCACCCCTCCTCCGCGCCGTCGAGCGCGACCACTACGAAATCGTCCGTCTGCTGCTC GACCACGGCGCCTGTCCCAACTCCGCCGACAAAGAAGGCCGCACGGCGCTCATGACCGCGGCGTGGAAGAACCAC GCCGATATCCTGCACCTGCTTATCATGCGGGGCGCGGACGTGAACCAGCGCGATCTGCGCCGCCGGAACGCGTTG CATAACCTCGCCGCTGATAGGGCTTGTCGGTGGGGGTGGGGGGAGGAGGTTGTGGGGTTGTTGTTGCGGACGGAG TGTGCTATTGATGGGGTTGCGGGGCAGGATGAGCTGGGGCGGACGCCGTTGCATTGGGCTTGTGCGACGGGGAAT TGGAGGATGGCGGAGATGTTGTTGACGAGGAATGCTGGCGAGGGGGAGAAAGAGGGGGAGGTGCGGGGGTCCGGG CTGGGGGCGCAGATCGATGCCGTTGAGCTGCGTGGTAAGACGGCGTTGCATGTTGCTACGGCTCATGACCGTGCG GATATCGTGCAGCTGCTGATTGCGCACAAGGCGGCGGTTAATGCTGCTAGTGATGGTGGCTGGACGCCGCTTCAT AATGCCTGTGATAAGGGGTGTGAGGCGATTGTGCGGATTCTGCTGAGCGAAGGCGCGCATATCAACGCACAGCTT TTGAATGGCATTACGCCGCTGCATCTTGCTGCGCAGGGCGGCCATCGCGAGGTCGTGCAGTGTCTTCTTGAGAAG CCTGATCTGAAACGTCGGGTTAGGGATAATTTTGGCAGTACGCCGTTTCTGCGTGCGGCGCAGTTCAAGCGGAAG GATATTGTGCTGTTGCTGGCGCCGTTTAACAATGTCGACAGTCTATCTGATGGTGTCAAGGAGGCTTGTGCGGCG TTCGATGCTACTGTTGTTGACTTTGGAAACTTCCATAATGAGAATCGGGTTAAGCGCATGTCGGTATTTAATCTG CTTTATGGGAGGGATCCGGAGAATCCTAGGAAACAGGCTGTTACCACTGTGCCGGTTGATAGTCGTGGGACTGAT TTCCGGTGGATTCACTTACCGGCGAACAATATGGCGTGGGTGGAAGCTCTGCTTACCAAGTCCTTTATTGAGGAG GGCGCACATGATGTTGATGGGTTCAAGGGGCTGGAGAAGTCTTTCAACTATCAGCATCGGGGTCAAAGGACTCAT TCGCACTTTATGCGACCGTTGTGTCAGAATACGCCGCGGACGATGCTGCGTCGACATGAAGAGGAGACTCCGGAG GAGCCTGCGTCTGAGAATGGGCAGGTAAGGGCCATGGATAGCCCTGCCCGCAAGCAAAAAGGCACAGGCAGCAAG CCTGAAAAGGCGGATTCTTATTTTCACGACGAAGGGCATGGAAAAAAGAACAAGAACAATCCGAAGCGCGGCAAG TCGGGTAGCGTACCAGGGACTCCCAAGCAGGAGACGAAGGGGAAGTCGGGCCAGGGCGAGAAACAGAGGTCATCA CTGTCTTCATCAACCTTTTGCAAAGACCCTCACCCTCTGGTTTCTGCATGTAATGTCTGCGTGTTCATGCCGTAT CTACATTTCGAGACCACAGAGCGCAGACAACAGATGCAGGATGCAATCTCCCGAGCGGAAACGCTTGATTTTATA CCCAGGGGGATAAAGAGAACGCGCACAAGAGACGAAATACTCATATATGCGCATCTATCGTCCTCAACGACCTCC CTCCATGTCCGCCGAACACTGGACCAGTTTTTCTACCCGAATATCGATACCAAGAGTCGTGATCAGGACCAAGTT GTGTACCGGTACCAAACAAAAAGCCCCGGAATGGGGGCAGACCCCAAGATATTCATGGTGGATCAACTCTGGATG TGGGTTCTAGGCACGAATCTGATTGTAACGGCCTTCCCGCAGAGATGGGACCAGCCCAAGAATGACCCGCTTAAT GTGCTGGATGGGATTATCGAGGATATCAATTCCAAAACCCGCGACCCTGTCAAATCCGTCTATGATCTAGCCATG ATAATCACCAATCGATGCTCGGGTGTCTTCGATCGACACCGCCTAGGCGACGAGGAGTACCAGTTCCTAGATATG TTCGAGTCATCTATAGGTATAGCCACGGACAAAGAGACCGTGCTTTTTAACCAATTCAACCACGCCTCCGGGCAG GCATCAGAGTGGCTGAAAAGTCACCGCAAGCTGAACGGCTCCTTCAGCTCTCCGCCAAAGTCCTACAATGGGACC GACGAGCAAGATCAAAGCAGCAACTACTGCGACGAGGACGGCCAGCCACTATTCGTCGACCGACTCCTAGACATC GGACAGGAAACCAATCTCCTAGCGGAGACAAAGGACATCAGAGACGAGCTGAACATGATCCGGACGGTGCTGGAG CACCAGAACAACGTCCTGCTCGACTTCCAAGAAGTCGTCTGCGAGACCTATCAAGGCCAGCACCGGTCCCAATTC GAAGTCAAGAAACGGTTCAAAGACCAGCAGCGCATGATCGACATGCACCTAAAGGATATTGACCGCATGGATAAA CAAGCCGAGCGCATCTACCACTCCATCACGGACCTGCTCGATCTGAAACAGAAACACGCGAACGCGTTCGAGGCC CGCTTCGCCCGTGACCAGGCTGCCGGTACAACCCGCCAGAGTAAGACAATTATGGTCTTCACTATTGTCACTATT GTCTTCCTGCCGTTGTCGTTTATCGCCTCCATCTTCACGATCAACCTGAAAGAATTCGAGAGCTTGAATCTCGGC TATGTGGCAAAGTATACCTTTGGTATTGGCTTTGCAATCTCCATCCCGCTTGTCTGGGTCGCTCTCACCGTTGAT GATATCGGGGGTTTCTTCCGCGTGGGCAGTCGACGCTGGTTGTCTAACCGGGCGAAGGTGTCTGCGAAGAGTGAA CGAAGCGAGGAAACGCTCCAGGCTTTGGAGATGGAGAAAATTATGAGTTTACCGCGCATGAGGAGGAGTGTCGAT GTGGAATATGGTGGTGGTCTGCTACCTGTTTCTACACGCGGCACGGGGGCCTCGAGGCGGCCTGATCTATATGGT GGATTGAGCAATGGCACTATGCGGAAAAGTTACGACCTGCGGCCTAGTATGGACTCCAGATTACGATGA