Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g5741.t1
Gene name
Location	scaffold_14:293403..296754
Strand	+
Gene length (bp)	3351
Transcript length (bp)	3351
Coding sequence length (bp)	3351
Protein length (aa)	1117

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF12157	DUF3591	Protein of unknown function (DUF3591)	2.0E-177	464	912

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 70	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
3d_25C	Three days - 25 degrees Celsius	26.47	16.10	36.84
5d_25C	Five days - 25 degrees Celsius	25.12	15.23	35.02
7d_25C	Seven days - 25 degrees Celsius	27.00	16.42	37.59
10d_25C	Ten days - 25 degrees Celsius	28.52	17.31	39.74
7d_15C	Seven days - 15 degrees Celsius	29.40	17.91	40.88
7d_30C	Seven days - 30 degrees Celsius	23.09	13.95	32.23

Differential expression

Label1	Label2	Q-value	Significant difference
3d_25C	5d_25C	0.874848	no
3d_25C	7d_25C	0.955459	no
3d_25C	7d_15C	0.714800	no
3d_25C	7d_30C	0.617007	no
3d_25C	10d_25C	0.813829	no
5d_25C	7d_25C	0.813222	no
5d_25C	7d_15C	0.549220	no
5d_25C	7d_30C	0.777364	no
5d_25C	10d_25C	0.650009	no
7d_25C	7d_15C	0.776759	no
7d_25C	7d_30C	0.554846	no
7d_25C	10d_25C	0.869453	no
7d_15C	7d_30C	0.307219	no
7d_15C	10d_25C	0.931489	no
7d_30C	10d_25C	0.396505	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g5741.t1 MPHATPKAPGGEDDTDFDDVMRQLNNYEDTGPSLDFLSRDLEVGEKAEDAIDYEDFDDDELPEEEETTRPAPALP AVDDNQDPFANLGSDDAALFGNGDDLFGDPGEGAQTQDDNLDDLFGEGSFSPPPAGQDDPTRGLFEDEDMPLTDA PVELPPIPSAPELQPEPPIMEEDEFPDDDSIMSEDMNPVELRAWKLQQQLFAMSGVENPPAPPENHEELLHSLFP SFDRNTLPRWLELIPHKKAIFIGKQPAKPPKPVLPTKVNIELAADHERAFRTGQLLKRGLDHETHGLVMITQSDR EEEGAEGDEDTKEDIDLDDLDGDEVLPGGFTMQDLRTICVDWDVKDDVSSIDPEEQPLAQRKDDTFDEDEADWLM ETEVPNKKRKTGPTPMDVIALSHIDIPLLDDPEQATMKIAKRVTIDLNDPNILVDELRADAVANKPKHAAPRTRD EVDLNLTRRLTQRYNISNDQAYDMLKQNHQNKIRSTLGNVTLEHGLPALRLQWPYYKTELAKAEARSFHRPALAF RPGQTSWVKNPTQVRRKHLRGKDAKTIYNSTKALSMSDNSNVLLVEYSEELPMTLANFGMCNRFINYYRRKNIDD PTRPRADIGETVVLLPQDKSPYSIFGHVDPGEISPAISNSMYRAPLFPHQTKSTDFLVVRSTTGFDGSSYYLRNI ENFYVAGQQFPSVDIPGPHSRKVTTVAKNRMKMLVYRLLKKSPDERLAISDVTAHIPNTTDMQNRQKVKDFLQHD KDTKYWKPLDPILPDQDTIRSWVQPEDVCLLESMQIGQQHLHDTGYGNDAETGGDNEEDEEFESFEQQMAPWKAT RNFLLASQGKAMLKLHGEGDPTGRGEGYNFIKTSMKGGFKAIGESVEDKLDAQRLKELGGHSYNVARQQKSYETS IRRIWDAQKSSLSSTIEHSDQESDVDQEDEYQDQFNKPTPRSEAQTPGPYRRDDETTSQFSKLSFNSQRGKVLRI TRQIRQENGEILHQEQHVFDPRVIRHYIQYRHQHEAMHIKLESLEPTGDTELDARNRKLIEAELGRLNRNKERRF AREKQKGIPRSGDPDGKPAGTQRKCANCGQVGHIKTNKKLCPLLNGTMKPEDRVTDSAFSMSAPVL*
Coding	>Pro_DTO377G3_2|g5741.t1 ATGCCTCACGCAACACCAAAGGCCCCCGGGGGCGAGGATGATACCGATTTCGACGATGTGATGCGACAACTGAAC AACTACGAAGATACTGGCCCCTCTCTAGATTTCTTGTCGCGTGATCTGGAAGTTGGTGAAAAAGCCGAAGATGCA ATCGACTACGAGGACTTCGACGACGATGAACTTCCGGAGGAAGAAGAGACGACACGCCCAGCTCCAGCCCTGCCT GCAGTGGATGATAATCAAGATCCTTTCGCGAACTTGGGCTCAGACGATGCTGCTCTTTTCGGAAACGGCGACGAT CTCTTCGGCGACCCGGGAGAGGGGGCTCAGACCCAGGATGACAATCTCGATGATCTCTTTGGCGAAGGTTCTTTT TCGCCGCCTCCTGCTGGACAGGATGATCCTACCCGCGGCCTCTTCGAAGACGAAGACATGCCCTTGACAGATGCG CCCGTTGAACTACCACCCATCCCGTCGGCCCCGGAATTGCAGCCAGAGCCACCTATCATGGAGGAAGATGAATTC CCGGATGATGACAGTATCATGTCGGAAGACATGAATCCCGTCGAACTCCGCGCATGGAAACTACAGCAGCAGTTG TTCGCCATGTCAGGGGTTGAAAACCCACCTGCACCACCCGAGAACCACGAAGAGCTTTTGCATTCCTTGTTTCCC TCGTTCGACCGGAACACTCTTCCACGTTGGCTCGAGTTGATTCCCCACAAGAAGGCTATCTTCATTGGAAAACAG CCGGCCAAGCCTCCTAAGCCCGTCTTGCCCACCAAAGTGAATATTGAGCTGGCAGCTGATCATGAGCGTGCATTC AGAACCGGGCAACTCCTCAAGCGTGGCCTCGATCATGAAACTCATGGCTTGGTGATGATTACACAATCGGACCGT GAAGAGGAGGGAGCAGAGGGGGATGAGGATACGAAGGAAGACATTGACCTGGATGATCTGGATGGAGATGAGGTA CTTCCGGGTGGCTTCACCATGCAGGACCTTCGAACGATTTGTGTGGACTGGGATGTTAAGGATGACGTCTCCAGC ATTGACCCGGAAGAGCAGCCATTGGCACAAAGAAAAGATGATACATTTGATGAGGATGAAGCGGATTGGCTGATG GAAACCGAGGTTCCGAACAAGAAACGAAAGACCGGCCCGACGCCGATGGATGTCATTGCTCTATCACATATCGAT ATTCCACTATTGGATGACCCAGAACAAGCGACAATGAAAATCGCAAAGCGAGTGACAATTGATCTCAATGATCCG AACATTCTTGTGGACGAATTAAGAGCGGATGCCGTCGCAAACAAGCCGAAACACGCAGCTCCTCGCACCAGGGAT GAAGTAGACCTGAATCTGACGCGCCGTCTCACCCAGCGCTACAACATTTCGAATGATCAAGCATACGACATGCTC AAACAGAATCATCAGAACAAGATCCGCAGTACTCTTGGCAATGTGACACTTGAGCACGGTCTGCCAGCCCTGCGT TTGCAATGGCCCTACTACAAGACTGAGTTGGCCAAGGCTGAAGCTAGATCTTTCCACCGACCTGCTTTGGCCTTC CGACCTGGGCAAACGTCTTGGGTCAAGAACCCTACCCAGGTGCGACGCAAGCACTTACGTGGCAAAGATGCGAAA ACTATCTATAATTCCACAAAGGCATTGTCCATGTCAGACAACTCCAATGTCTTGCTAGTGGAGTACTCCGAGGAG CTGCCCATGACACTAGCCAACTTTGGAATGTGCAACCGTTTCATCAATTATTACCGGCGAAAGAATATTGATGAT CCCACTCGCCCAAGGGCAGATATCGGGGAAACGGTTGTTCTCTTACCTCAAGACAAGAGCCCCTACTCAATCTTT GGCCATGTCGACCCCGGCGAAATTTCCCCGGCAATTTCAAACTCCATGTACCGAGCACCGCTATTCCCGCACCAG ACCAAATCTACGGACTTCCTCGTGGTCCGCAGTACCACTGGATTCGATGGCTCTAGCTATTACCTGCGTAACATC GAAAATTTCTACGTTGCCGGACAGCAATTCCCATCTGTAGACATTCCTGGACCTCATTCGCGCAAGGTGACAACT GTCGCCAAGAATCGCATGAAGATGCTGGTATATCGTTTGTTGAAGAAGAGCCCGGATGAGCGACTTGCAATCAGC GATGTTACAGCTCACATACCAAACACCACGGATATGCAGAACCGACAGAAGGTCAAGGATTTCCTTCAACACGAC AAGGACACTAAGTATTGGAAGCCACTGGATCCAATTCTCCCCGACCAAGACACAATCCGCTCATGGGTCCAGCCC GAAGATGTTTGTCTTCTGGAATCCATGCAGATTGGACAGCAACATCTCCACGACACTGGTTATGGCAACGATGCC GAGACCGGCGGCGATAACGAAGAAGATGAAGAATTCGAGAGCTTCGAGCAGCAGATGGCTCCGTGGAAGGCAACT CGCAACTTTTTATTGGCCTCTCAAGGCAAGGCGATGCTGAAACTTCATGGCGAAGGAGATCCTACTGGCCGTGGT GAGGGTTATAACTTCATCAAAACAAGCATGAAGGGTGGTTTCAAGGCTATCGGTGAAAGTGTTGAGGATAAGCTG GACGCGCAGCGACTTAAAGAGCTTGGAGGTCACAGCTACAATGTTGCCCGCCAGCAAAAATCTTACGAAACATCC ATTCGTCGGATTTGGGATGCTCAAAAAAGCAGTCTGTCCTCCACCATCGAGCATTCCGACCAGGAAAGCGACGTG GATCAAGAAGACGAATACCAGGATCAATTCAACAAACCAACACCTCGATCCGAAGCGCAGACACCTGGACCATAT CGTCGCGACGATGAGACAACAAGTCAGTTCAGCAAACTGAGTTTCAACAGCCAGCGCGGCAAAGTGCTGCGTATC ACCCGCCAGATCAGACAGGAAAACGGCGAAATTCTTCATCAGGAACAACATGTTTTCGATCCTCGAGTGATCAGG CACTATATCCAATACCGTCACCAACACGAAGCCATGCACATAAAGCTGGAATCTCTCGAACCCACGGGCGATACA GAACTCGACGCCCGTAACCGGAAGTTGATCGAGGCCGAGCTCGGCCGTCTCAACCGCAACAAGGAGCGTCGTTTC GCCCGCGAGAAGCAAAAGGGCATCCCTCGTTCCGGTGACCCGGACGGCAAGCCTGCTGGTACTCAGCGCAAGTGT GCCAACTGCGGCCAGGTCGGGCACATCAAAACAAACAAGAAACTCTGTCCATTGCTCAATGGTACTATGAAGCCC GAGGATCGTGTCACGGATTCGGCTTTCTCCATGAGCGCGCCGGTTCTGTAA
Transcript	>Pro_DTO377G3_2|g5741.t1 ATGCCTCACGCAACACCAAAGGCCCCCGGGGGCGAGGATGATACCGATTTCGACGATGTGATGCGACAACTGAAC AACTACGAAGATACTGGCCCCTCTCTAGATTTCTTGTCGCGTGATCTGGAAGTTGGTGAAAAAGCCGAAGATGCA ATCGACTACGAGGACTTCGACGACGATGAACTTCCGGAGGAAGAAGAGACGACACGCCCAGCTCCAGCCCTGCCT GCAGTGGATGATAATCAAGATCCTTTCGCGAACTTGGGCTCAGACGATGCTGCTCTTTTCGGAAACGGCGACGAT CTCTTCGGCGACCCGGGAGAGGGGGCTCAGACCCAGGATGACAATCTCGATGATCTCTTTGGCGAAGGTTCTTTT TCGCCGCCTCCTGCTGGACAGGATGATCCTACCCGCGGCCTCTTCGAAGACGAAGACATGCCCTTGACAGATGCG CCCGTTGAACTACCACCCATCCCGTCGGCCCCGGAATTGCAGCCAGAGCCACCTATCATGGAGGAAGATGAATTC CCGGATGATGACAGTATCATGTCGGAAGACATGAATCCCGTCGAACTCCGCGCATGGAAACTACAGCAGCAGTTG TTCGCCATGTCAGGGGTTGAAAACCCACCTGCACCACCCGAGAACCACGAAGAGCTTTTGCATTCCTTGTTTCCC TCGTTCGACCGGAACACTCTTCCACGTTGGCTCGAGTTGATTCCCCACAAGAAGGCTATCTTCATTGGAAAACAG CCGGCCAAGCCTCCTAAGCCCGTCTTGCCCACCAAAGTGAATATTGAGCTGGCAGCTGATCATGAGCGTGCATTC AGAACCGGGCAACTCCTCAAGCGTGGCCTCGATCATGAAACTCATGGCTTGGTGATGATTACACAATCGGACCGT GAAGAGGAGGGAGCAGAGGGGGATGAGGATACGAAGGAAGACATTGACCTGGATGATCTGGATGGAGATGAGGTA CTTCCGGGTGGCTTCACCATGCAGGACCTTCGAACGATTTGTGTGGACTGGGATGTTAAGGATGACGTCTCCAGC ATTGACCCGGAAGAGCAGCCATTGGCACAAAGAAAAGATGATACATTTGATGAGGATGAAGCGGATTGGCTGATG GAAACCGAGGTTCCGAACAAGAAACGAAAGACCGGCCCGACGCCGATGGATGTCATTGCTCTATCACATATCGAT ATTCCACTATTGGATGACCCAGAACAAGCGACAATGAAAATCGCAAAGCGAGTGACAATTGATCTCAATGATCCG AACATTCTTGTGGACGAATTAAGAGCGGATGCCGTCGCAAACAAGCCGAAACACGCAGCTCCTCGCACCAGGGAT GAAGTAGACCTGAATCTGACGCGCCGTCTCACCCAGCGCTACAACATTTCGAATGATCAAGCATACGACATGCTC AAACAGAATCATCAGAACAAGATCCGCAGTACTCTTGGCAATGTGACACTTGAGCACGGTCTGCCAGCCCTGCGT TTGCAATGGCCCTACTACAAGACTGAGTTGGCCAAGGCTGAAGCTAGATCTTTCCACCGACCTGCTTTGGCCTTC CGACCTGGGCAAACGTCTTGGGTCAAGAACCCTACCCAGGTGCGACGCAAGCACTTACGTGGCAAAGATGCGAAA ACTATCTATAATTCCACAAAGGCATTGTCCATGTCAGACAACTCCAATGTCTTGCTAGTGGAGTACTCCGAGGAG CTGCCCATGACACTAGCCAACTTTGGAATGTGCAACCGTTTCATCAATTATTACCGGCGAAAGAATATTGATGAT CCCACTCGCCCAAGGGCAGATATCGGGGAAACGGTTGTTCTCTTACCTCAAGACAAGAGCCCCTACTCAATCTTT GGCCATGTCGACCCCGGCGAAATTTCCCCGGCAATTTCAAACTCCATGTACCGAGCACCGCTATTCCCGCACCAG ACCAAATCTACGGACTTCCTCGTGGTCCGCAGTACCACTGGATTCGATGGCTCTAGCTATTACCTGCGTAACATC GAAAATTTCTACGTTGCCGGACAGCAATTCCCATCTGTAGACATTCCTGGACCTCATTCGCGCAAGGTGACAACT GTCGCCAAGAATCGCATGAAGATGCTGGTATATCGTTTGTTGAAGAAGAGCCCGGATGAGCGACTTGCAATCAGC GATGTTACAGCTCACATACCAAACACCACGGATATGCAGAACCGACAGAAGGTCAAGGATTTCCTTCAACACGAC AAGGACACTAAGTATTGGAAGCCACTGGATCCAATTCTCCCCGACCAAGACACAATCCGCTCATGGGTCCAGCCC GAAGATGTTTGTCTTCTGGAATCCATGCAGATTGGACAGCAACATCTCCACGACACTGGTTATGGCAACGATGCC GAGACCGGCGGCGATAACGAAGAAGATGAAGAATTCGAGAGCTTCGAGCAGCAGATGGCTCCGTGGAAGGCAACT CGCAACTTTTTATTGGCCTCTCAAGGCAAGGCGATGCTGAAACTTCATGGCGAAGGAGATCCTACTGGCCGTGGT GAGGGTTATAACTTCATCAAAACAAGCATGAAGGGTGGTTTCAAGGCTATCGGTGAAAGTGTTGAGGATAAGCTG GACGCGCAGCGACTTAAAGAGCTTGGAGGTCACAGCTACAATGTTGCCCGCCAGCAAAAATCTTACGAAACATCC ATTCGTCGGATTTGGGATGCTCAAAAAAGCAGTCTGTCCTCCACCATCGAGCATTCCGACCAGGAAAGCGACGTG GATCAAGAAGACGAATACCAGGATCAATTCAACAAACCAACACCTCGATCCGAAGCGCAGACACCTGGACCATAT CGTCGCGACGATGAGACAACAAGTCAGTTCAGCAAACTGAGTTTCAACAGCCAGCGCGGCAAAGTGCTGCGTATC ACCCGCCAGATCAGACAGGAAAACGGCGAAATTCTTCATCAGGAACAACATGTTTTCGATCCTCGAGTGATCAGG CACTATATCCAATACCGTCACCAACACGAAGCCATGCACATAAAGCTGGAATCTCTCGAACCCACGGGCGATACA GAACTCGACGCCCGTAACCGGAAGTTGATCGAGGCCGAGCTCGGCCGTCTCAACCGCAACAAGGAGCGTCGTTTC GCCCGCGAGAAGCAAAAGGGCATCCCTCGTTCCGGTGACCCGGACGGCAAGCCTGCTGGTACTCAGCGCAAGTGT GCCAACTGCGGCCAGGTCGGGCACATCAAAACAAACAAGAAACTCTGTCCATTGCTCAATGGTACTATGAAGCCC GAGGATCGTGTCACGGATTCGGCTTTCTCCATGAGCGCGCCGGTTCTGTAA
Gene	>Pro_DTO377G3_2|g5741.t1 ATGCCTCACGCAACACCAAAGGCCCCCGGGGGCGAGGATGATACCGATTTCGACGATGTGATGCGACAACTGAAC AACTACGAAGATACTGGCCCCTCTCTAGATTTCTTGTCGCGTGATCTGGAAGTTGGTGAAAAAGCCGAAGATGCA ATCGACTACGAGGACTTCGACGACGATGAACTTCCGGAGGAAGAAGAGACGACACGCCCAGCTCCAGCCCTGCCT GCAGTGGATGATAATCAAGATCCTTTCGCGAACTTGGGCTCAGACGATGCTGCTCTTTTCGGAAACGGCGACGAT CTCTTCGGCGACCCGGGAGAGGGGGCTCAGACCCAGGATGACAATCTCGATGATCTCTTTGGCGAAGGTTCTTTT TCGCCGCCTCCTGCTGGACAGGATGATCCTACCCGCGGCCTCTTCGAAGACGAAGACATGCCCTTGACAGATGCG CCCGTTGAACTACCACCCATCCCGTCGGCCCCGGAATTGCAGCCAGAGCCACCTATCATGGAGGAAGATGAATTC CCGGATGATGACAGTATCATGTCGGAAGACATGAATCCCGTCGAACTCCGCGCATGGAAACTACAGCAGCAGTTG TTCGCCATGTCAGGGGTTGAAAACCCACCTGCACCACCCGAGAACCACGAAGAGCTTTTGCATTCCTTGTTTCCC TCGTTCGACCGGAACACTCTTCCACGTTGGCTCGAGTTGATTCCCCACAAGAAGGCTATCTTCATTGGAAAACAG CCGGCCAAGCCTCCTAAGCCCGTCTTGCCCACCAAAGTGAATATTGAGCTGGCAGCTGATCATGAGCGTGCATTC AGAACCGGGCAACTCCTCAAGCGTGGCCTCGATCATGAAACTCATGGCTTGGTGATGATTACACAATCGGACCGT GAAGAGGAGGGAGCAGAGGGGGATGAGGATACGAAGGAAGACATTGACCTGGATGATCTGGATGGAGATGAGGTA CTTCCGGGTGGCTTCACCATGCAGGACCTTCGAACGATTTGTGTGGACTGGGATGTTAAGGATGACGTCTCCAGC ATTGACCCGGAAGAGCAGCCATTGGCACAAAGAAAAGATGATACATTTGATGAGGATGAAGCGGATTGGCTGATG GAAACCGAGGTTCCGAACAAGAAACGAAAGACCGGCCCGACGCCGATGGATGTCATTGCTCTATCACATATCGAT ATTCCACTATTGGATGACCCAGAACAAGCGACAATGAAAATCGCAAAGCGAGTGACAATTGATCTCAATGATCCG AACATTCTTGTGGACGAATTAAGAGCGGATGCCGTCGCAAACAAGCCGAAACACGCAGCTCCTCGCACCAGGGAT GAAGTAGACCTGAATCTGACGCGCCGTCTCACCCAGCGCTACAACATTTCGAATGATCAAGCATACGACATGCTC AAACAGAATCATCAGAACAAGATCCGCAGTACTCTTGGCAATGTGACACTTGAGCACGGTCTGCCAGCCCTGCGT TTGCAATGGCCCTACTACAAGACTGAGTTGGCCAAGGCTGAAGCTAGATCTTTCCACCGACCTGCTTTGGCCTTC CGACCTGGGCAAACGTCTTGGGTCAAGAACCCTACCCAGGTGCGACGCAAGCACTTACGTGGCAAAGATGCGAAA ACTATCTATAATTCCACAAAGGCATTGTCCATGTCAGACAACTCCAATGTCTTGCTAGTGGAGTACTCCGAGGAG CTGCCCATGACACTAGCCAACTTTGGAATGTGCAACCGTTTCATCAATTATTACCGGCGAAAGAATATTGATGAT CCCACTCGCCCAAGGGCAGATATCGGGGAAACGGTTGTTCTCTTACCTCAAGACAAGAGCCCCTACTCAATCTTT GGCCATGTCGACCCCGGCGAAATTTCCCCGGCAATTTCAAACTCCATGTACCGAGCACCGCTATTCCCGCACCAG ACCAAATCTACGGACTTCCTCGTGGTCCGCAGTACCACTGGATTCGATGGCTCTAGCTATTACCTGCGTAACATC GAAAATTTCTACGTTGCCGGACAGCAATTCCCATCTGTAGACATTCCTGGACCTCATTCGCGCAAGGTGACAACT GTCGCCAAGAATCGCATGAAGATGCTGGTATATCGTTTGTTGAAGAAGAGCCCGGATGAGCGACTTGCAATCAGC GATGTTACAGCTCACATACCAAACACCACGGATATGCAGAACCGACAGAAGGTCAAGGATTTCCTTCAACACGAC AAGGACACTAAGTATTGGAAGCCACTGGATCCAATTCTCCCCGACCAAGACACAATCCGCTCATGGGTCCAGCCC GAAGATGTTTGTCTTCTGGAATCCATGCAGATTGGACAGCAACATCTCCACGACACTGGTTATGGCAACGATGCC GAGACCGGCGGCGATAACGAAGAAGATGAAGAATTCGAGAGCTTCGAGCAGCAGATGGCTCCGTGGAAGGCAACT CGCAACTTTTTATTGGCCTCTCAAGGCAAGGCGATGCTGAAACTTCATGGCGAAGGAGATCCTACTGGCCGTGGT GAGGGTTATAACTTCATCAAAACAAGCATGAAGGGTGGTTTCAAGGCTATCGGTGAAAGTGTTGAGGATAAGCTG GACGCGCAGCGACTTAAAGAGCTTGGAGGTCACAGCTACAATGTTGCCCGCCAGCAAAAATCTTACGAAACATCC ATTCGTCGGATTTGGGATGCTCAAAAAAGCAGTCTGTCCTCCACCATCGAGCATTCCGACCAGGAAAGCGACGTG GATCAAGAAGACGAATACCAGGATCAATTCAACAAACCAACACCTCGATCCGAAGCGCAGACACCTGGACCATAT CGTCGCGACGATGAGACAACAAGTCAGTTCAGCAAACTGAGTTTCAACAGCCAGCGCGGCAAAGTGCTGCGTATC ACCCGCCAGATCAGACAGGAAAACGGCGAAATTCTTCATCAGGAACAACATGTTTTCGATCCTCGAGTGATCAGG CACTATATCCAATACCGTCACCAACACGAAGCCATGCACATAAAGCTGGAATCTCTCGAACCCACGGGCGATACA GAACTCGACGCCCGTAACCGGAAGTTGATCGAGGCCGAGCTCGGCCGTCTCAACCGCAACAAGGAGCGTCGTTTC GCCCGCGAGAAGCAAAAGGGCATCCCTCGTTCCGGTGACCCGGACGGCAAGCCTGCTGGTACTCAGCGCAAGTGT GCCAACTGCGGCCAGGTCGGGCACATCAAAACAAACAAGAAACTCTGTCCATTGCTCAATGGTACTATGAAGCCC GAGGATCGTGTCACGGATTCGGCTTTCTCCATGAGCGCGCCGGTTCTGTAA