Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g5620.t1
Gene name
Location	scaffold_13:589262..593182
Strand	+
Gene length (bp)	3920
Transcript length (bp)	3621
Coding sequence length (bp)	3621
Protein length (aa)	1207

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF13087	AAA_12	AAA domain	9.1E-41	684	870
PF13086	AAA_11	AAA domain	6.1E-14	295	425
PF13086	AAA_11	AAA domain	9.6E-08	590	669
PF13604	AAA_30	AAA domain	7.7E-08	296	368
PF13245	AAA_19	AAA domain	1.0E-06	300	367

GO

GO Term	Description	Terminal node
GO:0004386	helicase activity	Yes
GO:0140657	ATP-dependent activity	No
GO:0140640	catalytic activity, acting on a nucleic acid	No
GO:0003674	molecular_function	No
GO:0003824	catalytic activity	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 23	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g5620.t1 MSHFRFQYGHRPKEQVRPVNPEIRQYFDPDLPVYGPWKLWQTKPELPSTEEILGTDVSGDIVALTPNCISEPWVS KEKYLEAHYALIREDSVAPLRNAVARVRADPFMKDTQDISIYEKVFIIGVTLARAGLALHIQFSTRRAGKNIAWT YSNRLNPGTLVALTPKRNAFLSKCVVAVVACRLLESVEKDPPEVDLFLASPEDIEVDPQQEWIMVEARAGYFEAN RHTLTALQKLSKESFPLNEQICSLEEDIDAPGYINTAPSMDFSPLSEVSGLDITNKYDILERWPSQPMGKLDASQ WSALNRMLTKKLAIIQGPPGTGKTFTSLAALRMMLSNKGPKDPPIIIAAQTNHALDQLIKHISVFEKNYVRLGGR TSDPEIRKHTPYEIRQNQGLLTIEGGLMAPMRKKQNKLAAELEKVLKPLAPSNSNKPLAVSLFLEHGLLSQEQVD SLKEAAHKWQRSNTPANADPLAAWLSDCVKEFDSEYAGDFGFIDDDIDLEYEQLKEIEVEHGRYEDDWSSFKTRY YPLSGGLCSSNTAKVSRATVENLLKENDFYKIHKRYRGAVYGYLREQLMVILGEIVQRLAQTYKKCASNFQIGRF ERDYCILQEAKIIGMTTTGLSKYRGLVSSLKPRVILIEEAAEVLEAPVAVACLPSLQHLILVGDHQQLKGQCADY ELCGHPFYLDVSMFERLMINKMPYAMLQEQRRMVPEIRELVAPIYGNLLHDHPSVGDHPFVPGMGDKRSFFFDHT AHESNDSLLSKVNDFEASMVVNLLAYLVMNKVPASSITVLTFYNGQRKLIMRKKAQNPNVAKPYVNIVTVDSYQG EENDIVILSLVRSNDHRGIGFLAQDNRVCVALSRAKYGLYIFGNARCVSKHSEFWYAVTNVMSEKKEDPRIGPAL PLYCTRHNQETLIETLKDWNTIGDGCDKPCGTNLPCGHPCPRKCHGSEHDWVSCKQRCREIRECCNTFCICVCSP PHTHDCFCGMGKDNKTQIFDGGSDWDDVDGEEDDRDEKVGPIPRTRAPTRASASASVSASTAEDTARCAEGVRQW QAFARGGGVLDDYRRAGLDASGKRPQKDAIPVEQNVVAPVQGTLIDFDDDADDADDGQVEVLGAGEDALAERGIF ARDSDGQVEAMSEVQDTPPTLDNDLINFEEDDDGYQAEGVSQPIMRLPSMRLPSMLVEVSLTSRVEEVAASPFGG DLIELS*
Coding	>Pro_DTO377G3_2|g5620.t1 ATGTCCCACTTTCGCTTTCAGTATGGTCATAGACCCAAGGAACAGGTCAGACCGGTTAATCCTGAGATCCGCCAG TACTTCGACCCAGATCTACCAGTCTACGGCCCTTGGAAGCTTTGGCAAACTAAGCCCGAGCTTCCTTCGACCGAA GAGATCCTCGGGACAGACGTATCAGGAGATATTGTCGCTCTTACCCCCAATTGCATTTCGGAGCCTTGGGTCTCC AAGGAGAAATACCTAGAGGCCCATTATGCATTGATCCGGGAAGACTCAGTTGCACCACTTCGAAATGCCGTGGCT CGGGTTCGCGCTGATCCTTTTATGAAGGATACTCAGGATATCTCCATCTATGAGAAGGTCTTCATTATCGGTGTT ACCCTAGCCCGAGCGGGTTTGGCGTTGCACATCCAATTCTCAACTCGTCGTGCGGGCAAGAATATTGCCTGGACA TACTCTAACCGTCTTAATCCTGGAACACTCGTCGCCCTTACCCCCAAGCGCAATGCATTCTTGAGCAAATGTGTT GTCGCCGTCGTAGCTTGTCGGCTGCTGGAATCGGTTGAGAAAGACCCCCCAGAGGTCGATCTCTTCTTGGCCTCA CCCGAGGATATCGAGGTTGATCCACAGCAAGAATGGATCATGGTTGAGGCTCGAGCGGGATATTTTGAAGCAAAT AGACACACCTTGACAGCACTGCAGAAGTTGTCAAAGGAAAGTTTCCCGTTGAACGAACAAATCTGCAGCCTGGAG GAAGACATTGATGCACCAGGATACATCAACACCGCACCATCCATGGACTTCTCGCCATTGTCCGAAGTCTCTGGA CTCGATATCACGAACAAATACGACATCCTCGAGAGATGGCCCTCCCAGCCAATGGGAAAGCTAGATGCATCCCAG TGGTCAGCCCTGAACCGAATGTTGACTAAAAAGCTGGCCATCATCCAGGGTCCCCCTGGAACGGGCAAAACCTTT ACCTCTCTCGCTGCTCTGAGGATGATGCTCTCGAACAAAGGGCCCAAGGATCCACCGATAATCATCGCCGCTCAA ACCAACCATGCTCTAGATCAACTTATCAAGCATATCTCGGTGTTCGAGAAGAACTATGTCCGGCTGGGTGGAAGA ACTTCCGATCCTGAGATTCGCAAGCACACTCCTTATGAGATCAGACAGAACCAGGGTCTATTGACAATTGAGGGG GGCTTGATGGCTCCAATGAGAAAGAAACAGAACAAACTCGCGGCTGAGCTTGAGAAGGTCCTAAAGCCACTTGCG CCATCAAACAGCAACAAGCCCCTTGCAGTATCTCTATTTCTGGAGCATGGTCTTTTGAGCCAAGAGCAAGTTGAT TCCTTGAAGGAAGCTGCACACAAATGGCAGCGATCCAACACTCCTGCAAATGCCGATCCTTTGGCGGCTTGGCTT TCAGACTGCGTGAAGGAGTTTGACTCCGAATACGCCGGTGACTTTGGGTTCATCGATGATGATATTGACCTGGAG TATGAGCAACTCAAAGAGATCGAAGTCGAACACGGAAGATATGAGGATGACTGGTCGTCTTTCAAAACACGCTAT TACCCCTTGTCGGGTGGTCTTTGCAGCTCCAACACCGCCAAAGTCTCTCGGGCAACAGTTGAAAATCTGCTAAAA GAGAATGACTTTTACAAAATCCACAAGAGGTATCGCGGTGCTGTCTATGGCTACCTACGTGAGCAGCTGATGGTT ATCCTGGGAGAAATTGTGCAGCGCCTCGCTCAAACCTACAAAAAATGCGCCTCCAATTTTCAAATTGGTAGGTTT GAACGGGACTACTGTATTCTCCAGGAGGCGAAGATCATTGGAATGACCACCACTGGTCTGAGCAAATACAGAGGA CTGGTCTCGAGTTTGAAACCCCGAGTCATCTTGATCGAAGAGGCAGCAGAAGTACTTGAGGCCCCAGTTGCAGTC GCTTGTCTTCCGTCACTTCAGCATCTTATCCTTGTTGGTGATCACCAGCAGCTTAAGGGTCAATGTGCGGACTAT GAACTGTGCGGGCACCCTTTCTACCTCGATGTCTCTATGTTTGAGCGTCTGATGATAAACAAAATGCCATACGCC ATGCTTCAAGAGCAGAGACGAATGGTGCCAGAAATCAGAGAGCTCGTGGCCCCCATCTATGGGAATCTTCTTCAT GACCATCCGTCTGTTGGAGATCACCCTTTTGTTCCTGGCATGGGAGACAAGCGATCATTCTTTTTCGACCACACT GCGCATGAAAGCAACGACAGTCTGCTATCCAAGGTGAATGACTTTGAGGCATCAATGGTGGTCAATCTTCTTGCC TACCTGGTGATGAACAAAGTCCCGGCATCCAGTATCACTGTCCTGACTTTCTACAATGGCCAACGGAAATTGATC ATGCGAAAGAAGGCACAGAATCCCAACGTCGCCAAACCATACGTCAATATAGTGACCGTCGACTCATACCAAGGA GAAGAGAACGATATCGTCATCCTCTCGCTTGTTCGATCCAATGATCATCGAGGTATCGGCTTTCTCGCGCAGGAC AATAGAGTTTGTGTCGCCTTGTCGCGCGCCAAATACGGTCTTTACATATTTGGCAATGCACGATGTGTTAGCAAA CACAGTGAGTTTTGGTATGCAGTTACTAATGTGATGTCGGAGAAAAAAGAAGACCCTCGTATCGGCCCGGCTCTG CCTCTGTACTGCACACGACACAACCAAGAAACCCTCATCGAGACTCTCAAGGACTGGAACACCATCGGTGACGGC TGCGACAAGCCTTGTGGCACGAATTTACCATGCGGACATCCATGTCCCCGCAAATGCCACGGTTCCGAACACGAC TGGGTCTCCTGCAAACAGCGCTGCCGTGAAATTCGCGAGTGCTGTAACACGTTCTGCATTTGTGTGTGCTCTCCA CCACACACTCACGATTGCTTCTGCGGTATGGGCAAGGACAACAAAACCCAGATCTTCGACGGCGGATCCGACTGG GATGATGTCGATGGCGAAGAAGATGATCGCGACGAAAAGGTCGGCCCCATCCCCCGGACCCGAGCCCCAACCCGT GCCTCCGCCTCTGCCTCTGTCTCTGCCTCCACCGCAGAAGATACAGCTCGTTGCGCCGAGGGTGTACGCCAATGG CAGGCGTTTGCGCGTGGTGGTGGCGTGTTGGATGATTATCGTCGGGCTGGGCTTGACGCTAGCGGGAAACGTCCT CAGAAAGATGCTATTCCAGTTGAACAGAACGTGGTTGCTCCGGTTCAAGGCACTCTTATCGACTTCGACGATGAT GCCGATGATGCCGATGATGGTCAGGTTGAAGTTCTGGGTGCAGGGGAAGACGCCCTGGCTGAGAGGGGCATCTTC GCACGTGATAGTGATGGTCAGGTCGAAGCTATGAGTGAAGTACAAGACACGCCTCCTACTCTCGACAATGACTTG ATAAACTTCGAAGAGGATGATGATGGCTACCAAGCTGAAGGTGTGAGTCAACCGATAATGCGGCTTCCTTCGATG CGGCTTCCTTCTATGTTAGTCGAAGTTTCGCTTACTTCCAGGGTCGAGGAAGTCGCGGCGTCTCCATTTGGGGGG GATCTGATCGAGCTTTCCTAG
Transcript	>Pro_DTO377G3_2|g5620.t1 ATGTCCCACTTTCGCTTTCAGTATGGTCATAGACCCAAGGAACAGGTCAGACCGGTTAATCCTGAGATCCGCCAG TACTTCGACCCAGATCTACCAGTCTACGGCCCTTGGAAGCTTTGGCAAACTAAGCCCGAGCTTCCTTCGACCGAA GAGATCCTCGGGACAGACGTATCAGGAGATATTGTCGCTCTTACCCCCAATTGCATTTCGGAGCCTTGGGTCTCC AAGGAGAAATACCTAGAGGCCCATTATGCATTGATCCGGGAAGACTCAGTTGCACCACTTCGAAATGCCGTGGCT CGGGTTCGCGCTGATCCTTTTATGAAGGATACTCAGGATATCTCCATCTATGAGAAGGTCTTCATTATCGGTGTT ACCCTAGCCCGAGCGGGTTTGGCGTTGCACATCCAATTCTCAACTCGTCGTGCGGGCAAGAATATTGCCTGGACA TACTCTAACCGTCTTAATCCTGGAACACTCGTCGCCCTTACCCCCAAGCGCAATGCATTCTTGAGCAAATGTGTT GTCGCCGTCGTAGCTTGTCGGCTGCTGGAATCGGTTGAGAAAGACCCCCCAGAGGTCGATCTCTTCTTGGCCTCA CCCGAGGATATCGAGGTTGATCCACAGCAAGAATGGATCATGGTTGAGGCTCGAGCGGGATATTTTGAAGCAAAT AGACACACCTTGACAGCACTGCAGAAGTTGTCAAAGGAAAGTTTCCCGTTGAACGAACAAATCTGCAGCCTGGAG GAAGACATTGATGCACCAGGATACATCAACACCGCACCATCCATGGACTTCTCGCCATTGTCCGAAGTCTCTGGA CTCGATATCACGAACAAATACGACATCCTCGAGAGATGGCCCTCCCAGCCAATGGGAAAGCTAGATGCATCCCAG TGGTCAGCCCTGAACCGAATGTTGACTAAAAAGCTGGCCATCATCCAGGGTCCCCCTGGAACGGGCAAAACCTTT ACCTCTCTCGCTGCTCTGAGGATGATGCTCTCGAACAAAGGGCCCAAGGATCCACCGATAATCATCGCCGCTCAA ACCAACCATGCTCTAGATCAACTTATCAAGCATATCTCGGTGTTCGAGAAGAACTATGTCCGGCTGGGTGGAAGA ACTTCCGATCCTGAGATTCGCAAGCACACTCCTTATGAGATCAGACAGAACCAGGGTCTATTGACAATTGAGGGG GGCTTGATGGCTCCAATGAGAAAGAAACAGAACAAACTCGCGGCTGAGCTTGAGAAGGTCCTAAAGCCACTTGCG CCATCAAACAGCAACAAGCCCCTTGCAGTATCTCTATTTCTGGAGCATGGTCTTTTGAGCCAAGAGCAAGTTGAT TCCTTGAAGGAAGCTGCACACAAATGGCAGCGATCCAACACTCCTGCAAATGCCGATCCTTTGGCGGCTTGGCTT TCAGACTGCGTGAAGGAGTTTGACTCCGAATACGCCGGTGACTTTGGGTTCATCGATGATGATATTGACCTGGAG TATGAGCAACTCAAAGAGATCGAAGTCGAACACGGAAGATATGAGGATGACTGGTCGTCTTTCAAAACACGCTAT TACCCCTTGTCGGGTGGTCTTTGCAGCTCCAACACCGCCAAAGTCTCTCGGGCAACAGTTGAAAATCTGCTAAAA GAGAATGACTTTTACAAAATCCACAAGAGGTATCGCGGTGCTGTCTATGGCTACCTACGTGAGCAGCTGATGGTT ATCCTGGGAGAAATTGTGCAGCGCCTCGCTCAAACCTACAAAAAATGCGCCTCCAATTTTCAAATTGGTAGGTTT GAACGGGACTACTGTATTCTCCAGGAGGCGAAGATCATTGGAATGACCACCACTGGTCTGAGCAAATACAGAGGA CTGGTCTCGAGTTTGAAACCCCGAGTCATCTTGATCGAAGAGGCAGCAGAAGTACTTGAGGCCCCAGTTGCAGTC GCTTGTCTTCCGTCACTTCAGCATCTTATCCTTGTTGGTGATCACCAGCAGCTTAAGGGTCAATGTGCGGACTAT GAACTGTGCGGGCACCCTTTCTACCTCGATGTCTCTATGTTTGAGCGTCTGATGATAAACAAAATGCCATACGCC ATGCTTCAAGAGCAGAGACGAATGGTGCCAGAAATCAGAGAGCTCGTGGCCCCCATCTATGGGAATCTTCTTCAT GACCATCCGTCTGTTGGAGATCACCCTTTTGTTCCTGGCATGGGAGACAAGCGATCATTCTTTTTCGACCACACT GCGCATGAAAGCAACGACAGTCTGCTATCCAAGGTGAATGACTTTGAGGCATCAATGGTGGTCAATCTTCTTGCC TACCTGGTGATGAACAAAGTCCCGGCATCCAGTATCACTGTCCTGACTTTCTACAATGGCCAACGGAAATTGATC ATGCGAAAGAAGGCACAGAATCCCAACGTCGCCAAACCATACGTCAATATAGTGACCGTCGACTCATACCAAGGA GAAGAGAACGATATCGTCATCCTCTCGCTTGTTCGATCCAATGATCATCGAGGTATCGGCTTTCTCGCGCAGGAC AATAGAGTTTGTGTCGCCTTGTCGCGCGCCAAATACGGTCTTTACATATTTGGCAATGCACGATGTGTTAGCAAA CACAGTGAGTTTTGGTATGCAGTTACTAATGTGATGTCGGAGAAAAAAGAAGACCCTCGTATCGGCCCGGCTCTG CCTCTGTACTGCACACGACACAACCAAGAAACCCTCATCGAGACTCTCAAGGACTGGAACACCATCGGTGACGGC TGCGACAAGCCTTGTGGCACGAATTTACCATGCGGACATCCATGTCCCCGCAAATGCCACGGTTCCGAACACGAC TGGGTCTCCTGCAAACAGCGCTGCCGTGAAATTCGCGAGTGCTGTAACACGTTCTGCATTTGTGTGTGCTCTCCA CCACACACTCACGATTGCTTCTGCGGTATGGGCAAGGACAACAAAACCCAGATCTTCGACGGCGGATCCGACTGG GATGATGTCGATGGCGAAGAAGATGATCGCGACGAAAAGGTCGGCCCCATCCCCCGGACCCGAGCCCCAACCCGT GCCTCCGCCTCTGCCTCTGTCTCTGCCTCCACCGCAGAAGATACAGCTCGTTGCGCCGAGGGTGTACGCCAATGG CAGGCGTTTGCGCGTGGTGGTGGCGTGTTGGATGATTATCGTCGGGCTGGGCTTGACGCTAGCGGGAAACGTCCT CAGAAAGATGCTATTCCAGTTGAACAGAACGTGGTTGCTCCGGTTCAAGGCACTCTTATCGACTTCGACGATGAT GCCGATGATGCCGATGATGGTCAGGTTGAAGTTCTGGGTGCAGGGGAAGACGCCCTGGCTGAGAGGGGCATCTTC GCACGTGATAGTGATGGTCAGGTCGAAGCTATGAGTGAAGTACAAGACACGCCTCCTACTCTCGACAATGACTTG ATAAACTTCGAAGAGGATGATGATGGCTACCAAGCTGAAGGTGTGAGTCAACCGATAATGCGGCTTCCTTCGATG CGGCTTCCTTCTATGTTAGTCGAAGTTTCGCTTACTTCCAGGGTCGAGGAAGTCGCGGCGTCTCCATTTGGGGGG GATCTGATCGAGCTTTCCTAG
Gene	>Pro_DTO377G3_2|g5620.t1 ATGTCCCACTTTCGCTTTCAGTATGGTCATAGACCCAAGGAACAGGTCAGACCGGTTAATCCTGAGATCCGCCAG TACTTCGACCCAGATCTACCAGTCTACGGCCCTTGGAAGCTTTGGCAAACTAAGCCCGAGCTTCCTTCGACCGAA GAGATCCTCGGGACAGACGTATCAGGAGATATTGTCGCTCTTACCCCCAATTGCATTTCGGAGCCTTGGGTCTCC AAGGAGAAATACCTAGAGGCCCATTATGCATTGATCCGGGAAGACTCAGTTGCACCACTTCGAAATGCCGTGGCT CGGGTTCGCGCTGATCCTTTTATGAAGGATACTCAGGATATCTCCATCTATGAGAAGGTGAGTACTGCTCTGTCG TTGGAATTTCTTGGATTTGGATAGTACTGACCATCTCTTTACATCAAAGGTCTTCATTATCGGTGTTACCCTAGC CCGAGCGGGTTTGGCGTTGCACATCCAATTCTCAACTCGTCGTGCGGGCAAGAATATTGCCTGGACATACTCTAA CCGTCTTAATCCTGGAACACTCGTCGCCCTTACCCCCAAGCGCAATGCATTCTTGAGCAAATGTGTTGTCGCCGT CGTAGCTTGTCGGCTGCTGGAATCGGTTGAGAAAGACCCCCCAGAGGTCGATCTCTTCTTGGCCTCACCCGAGGA TATCGAGGTTGATCCACAGTGAGCAATACTATGGTTCAGTGGTTTTGAAAGATATAACAATACTGACTAGTATAT CTCAGGCAAGAATGGATCATGGTTGAGGCTCGAGCGGGATATTTTGAAGCAAATAGACACACCTTGACAGCACTG CAGAAGTTGTCAAAGGAAAGGTCAGCGGCAAATCGTATCTCCCTTATTGAAATTTACCTGACCTTATCTAGTTTC CCGTTGAACGAACAAATCTGCAGCCTGGAGGAAGACATTGATGCACCAGGATACATCAACACCGCACCATCCATG GACTTCTCGCCATTGTCCGAAGTCTCTGGACTCGATATCACGAACAAATACGACATCCTCGAGAGATGGCCCTCC CAGCCAATGGGAAAGCTAGATGCATCCCAGTGGTCAGCCCTGAACCGAATGTTGACTAAAAAGCTGGCCATCATC CAGGGTCCCCCTGGAACGGGCAAAACCTTTACCTCTCTCGCTGCTCTGAGGATGATGCTCTCGAACAAAGGGCCC AAGGATCCACCGATAATCATCGCCGCTCAAACCAACCATGCTCTAGATCAACTTATCAAGCATATCTCGGTGTTC GAGAAGAACTATGTCCGGCTGGGTGGAAGAACTTCCGATCCTGAGATTCGCAAGCACACTCCTTATGAGATCAGA CAGAACCAGGGTCTATTGACAATTGAGGGGGGCTTGATGGCTCCAATGAGAAAGAAACAGAACAAACTCGCGGCT GAGCTTGAGAAGGTCCTAAAGCCACTTGCGCCATCAAACAGCAACAAGCCCCTTGCAGTATCTCTATTTCTGGAG CATGGTCTTTTGAGCCAAGAGCAAGTTGATTCCTTGAAGGAAGCTGCACACAAATGGCAGCGATCCAACACTCCT GCAAATGCCGATCCTTTGGCGGCTTGGCTTTCAGACTGCGTGAAGGAGTTTGACTCCGAATACGCCGGTGACTTT GGGTTCATCGATGATGATATTGACCTGGAGTATGAGCAACTCAAAGAGATCGAAGTCGAACACGGAAGATATGAG GATGACTGGTCGTCTTTCAAAACACGCTATTACCCCTTGTCGGGTGGTCTTTGCAGCTCCAACACCGCCAAAGTC TCTCGGGCAACAGTTGAAAATCTGCTAAAAGAGAATGACTTTTACAAAATCCACAAGAGGTATCGCGGTGCTGTC TATGGCTACCTACGTGAGCAGCTGATGGTTATCCTGGGAGAAATTGTGCAGCGCCTCGCTCAAACCTACAAAAAA TGCGCCTCCAATTTTCAAATTGGTAGGTTTGAACGGGACTACTGTATTCTCCAGGAGGCGAAGATCATTGGAATG ACCACCACTGGTCTGAGCAAATACAGAGGACTGGTCTCGAGTTTGAAACCCCGAGTCATCTTGATCGAAGAGGCA GCAGAAGTACTTGAGGCCCCAGTTGCAGTCGCTTGTCTTCCGTCACTTCAGCATCTTATCCTTGTTGGTGATCAC CAGCAGCTTAAGGGTCAATGTGCGGACTATGAACTGTGCGGGCACCCTTTCTACCTCGATGTCTCTATGTTTGAG CGTCTGATGATAAACAAAATGCCATACGCCATGCTTCAAGAGCAGAGACGAATGGTGCCAGAAATCAGAGAGCTC GTGGCCCCCATCTATGGGAATCTTCTTCATGACCATCCGTCTGTTGGAGATCACCCTTTTGTTCCTGGCATGGGA GACAAGCGATCATTCTTTTTCGACCACACTGCGCATGAAAGCAACGACAGTCTGCTATCCAAGGTGAATGACTTT GAGGCATCAATGGTGGTCAATCTTCTTGCCTACCTGGTGATGAACAAAGTCCCGGCATCCAGTATCACTGTCCTG ACTTTCTACAATGGCCAACGGAAATTGATCATGCGAAAGAAGGCACAGAATCCCAACGTCGCCAAACCATACGTC AATATAGTGACCGTCGACTCATACCAAGGAGAAGAGAACGATATCGTCATCCTCTCGCTTGTTCGATCCAATGAT CATCGAGGTATCGGCTTTCTCGCGCAGGACAATAGAGTTTGTGTCGCCTTGTCGCGCGCCAAATACGGTCTTTAC ATATTTGGCAATGCACGATGTGTTAGCAAACACAGTGAGTTTTGGTATGCAGTTACTAATGTGATGTCGGAGAAA AAAGAAGACCCTCGTATCGGCCCGGCTCTGCCTCTGTACTGCACACGACACAACCAAGAAACCCTCATCGAGAGT GAGTCCCTGTCCTGCCTAGTGATATCAACGGAAGAGATGATCTAACCGTTTTTCTAGCTCTCAAGGACTGGAACA CCATCGGTGACGGCTGCGACAAGCCTTGTGGCACGAATTTACCATGCGGACATCCATGTCCCCGCAAATGCCACG GGTAAGTTTCGCGAATAATGACAGTTTCCATGCACCCAATACTGACATCTTGACTCATTAGTTCCGAACACGACT GGGTCTCCTGCAAACAGCGCTGCCGTGAAATTCGCGAGTGCTGTAACACGTTCTGCATTTGTGTGTGCTCTCCAC CACACACTCACGATTGCTTCTGCGGTATGGGCAAGGACAACAAAACCCAGATCTTCGACGGCGGATCCGACTGGG ATGATGTCGATGGCGAAGAAGATGATCGCGACGAAAAGGTCGGCCCCATCCCCCGGACCCGAGCCCCAACCCGTG CCTCCGCCTCTGCCTCTGTCTCTGCCTCCACCGCAGAAGATACAGCTCGTTGCGCCGAGGGTGTACGCCAATGGC AGGCGTTTGCGCGTGGTGGTGGCGTGTTGGATGATTATCGTCGGGCTGGGCTTGACGCTAGCGGGAAACGTCCTC AGAAAGATGCTATTCCAGTTGAACAGAACGTGGTTGCTCCGGTTCAAGGCACTCTTATCGACTTCGACGATGATG CCGATGATGCCGATGATGGTCAGGTTGAAGTTCTGGGTGCAGGGGAAGACGCCCTGGCTGAGAGGGGCATCTTCG CACGTGATAGTGATGGTCAGGTCGAAGCTATGAGTGAAGTACAAGACACGCCTCCTACTCTCGACAATGACTTGA TAAACTTCGAAGAGGATGATGATGGCTACCAAGCTGAAGGTGTGAGTCAACCGATAATGCGGCTTCCTTCGATGC GGCTTCCTTCTATGTTAGTCGAAGTTTCGCTTACTTCCAGGGTCGAGGAAGTCGCGGCGTCTCCATTTGGGGGGG ATCTGATCGAGCTTTCCTAG