Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g5260.t1
Gene name
Location	scaffold_12:323549..327284
Strand	-
Gene length (bp)	3735
Transcript length (bp)	3540
Coding sequence length (bp)	3540
Protein length (aa)	1180

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00176	SNF2_N	SNF2 family N-terminal domain	1.5E-64	498	806
PF00271	Helicase_C	Helicase conserved C-terminal domain	6.1E-16	1006	1119
PF13923	zf-C3HC4_2	Zinc finger, C3HC4 type (RING finger)	4.7E-08	848	876
PF04851	ResIII	Type III restriction enzyme, res subunit	2.2E-06	486	670
PF13920	zf-C3HC4_3	Zinc finger, C3HC4 type (RING finger)	2.6E-06	845	905
PF00097	zf-C3HC4	Zinc finger, C3HC4 type (RING finger)	1.8E-04	848	879

GO

GO Term	Description	Terminal node
GO:0046872	metal ion binding	Yes
GO:0016787	hydrolase activity	Yes
GO:0003677	DNA binding	Yes
GO:0005524	ATP binding	Yes
GO:0030554	adenyl nucleotide binding	No
GO:1901363	heterocyclic compound binding	No
GO:0032555	purine ribonucleotide binding	No
GO:0097159	organic cyclic compound binding	No
GO:0032553	ribonucleotide binding	No
GO:0003824	catalytic activity	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0043168	anion binding	No
GO:1901265	nucleoside phosphate binding	No
GO:0017076	purine nucleotide binding	No
GO:0097367	carbohydrate derivative binding	No
GO:0008144	drug binding	No
GO:0000166	nucleotide binding	No
GO:0003674	molecular_function	No
GO:0043167	ion binding	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0003676	nucleic acid binding	No
GO:0005488	binding	No
GO:0043169	cation binding	No
GO:0036094	small molecule binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 41	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g5260.t1 MASSVDQSQEDKIKDLLEDLDTYRYIYDDLLATRGPCAEADELRDTIKNMEVQVATLLGDPVPTSQAAPTPQVTS PTPPVRTPAATPRKASNTFTGIPGDSFASPHWPSAAPSPFAAGSGQSILLPASSMIQPSPDNSRKRQRPLSQVSP TIQGSSKRIAPSQPKSHRSKLDEIDAAQEARLAENQRLYKHWIDAAGDDADEINELREECEEQAKLIETEFQMER DAELARALQADEDHSQLPRSNERHTWNIPDRSQPVKLEHLSSNPNRAPQAYAPIAPFNKLNPFNSDDDLQEITAD SFKDRSGKQPARPSSSYPHLPSLPSQYSKSPYTSQGLYPSRMPYPSELTYPSQLPYPSELTYPSQMSYPSQLPYP SQLAYPSQLSNSSMPYSTSAAASRNLPWSHEHPYATMPGTFEKYDKFDKFDKAFDLVRNQSEIFDDDADIVAYNE KEFPEDIKNLLSGIKDIREATKADNDETPSALRVTLMKHQKIGLRWMKAKEESNHKGGILADDMGLGKTIQAIAL MVARPFEDEDRRPTLIVAPKALMDQWRLEIQRHVKPGRHQLSVLIYHQRRRPWKELKRYDIIITTFGTITAHYKT LLQAEKLAEEGRDPSIIQDLKNAAGPLSPAAKWHRVIIDEAQNIKNPSAKSAIACCRLNATYRWCLTGTPMMNRL EDFQSLLGFLRIRPYSNPAKFKADFVRRIKSGWGGEDVMKQLRVLVKSVCLRRTKSSKIDGEPILQLPPKVTEKV HVVFDERESQVYEELNTSTQRQITRYLDSGTLGRNYSHVLVLLLRLRQACCHPLLMQDFRNEPSPSIPGVDKIAN AKLLTAAVVQRIKDNDGEEDGTCPVCMDSVKNATIYIPCGHHVCSECWIRISDSATANGAINLEDDGPAVIKCQN CRGPVDPAKLTDTNAFKQVHDPTSVPEFAAGGGDTNGPNDDEDPEATASSEESDSDSSTGEGDAESKKKTKAKSL AQLRKDALRNKAEKKKYIRRLEKGWFPSTKITKTLEILQANEDRGLEEKTIIFSQFTSLLDLLEVPLARRGWNHT RFDGSMNLKERNAAVTAFTNDPDCKIMLVSLKAGNSGLNLVAASHVIMFDPFWNPYIEDQAVDRAHRIGQVREVF VHRLLIENTVEDRIVTLQDQKRELISGALDEGGTMNVSRLDARELAYLFGVRDL*
Coding	>Pro_DTO377G3_2|g5260.t1 ATGGCTTCTTCGGTCGATCAGTCCCAAGAGGACAAGATCAAAGACCTTTTGGAGGATCTCGATACCTACAGATAC ATATACGATGATCTCCTCGCGACGCGGGGTCCTTGTGCAGAAGCAGATGAGCTTCGTGATACCATCAAAAATATG GAAGTCCAGGTTGCCACGCTCCTTGGTGATCCTGTTCCTACTTCTCAAGCCGCCCCAACACCACAAGTGACATCC CCTACTCCGCCAGTCCGGACGCCTGCGGCTACTCCACGCAAGGCGTCCAACACTTTCACTGGAATCCCCGGGGAT TCATTTGCGTCCCCTCACTGGCCTTCTGCTGCACCCTCACCTTTCGCGGCCGGATCTGGCCAATCGATATTGCTG CCAGCTTCATCAATGATACAGCCTTCTCCAGATAATTCCCGTAAACGCCAGCGTCCGCTATCTCAGGTCTCGCCC ACGATCCAGGGATCATCAAAAAGGATTGCTCCCTCGCAGCCTAAATCTCACAGATCTAAACTCGACGAGATAGAT GCTGCACAAGAAGCCCGCCTTGCCGAGAATCAGCGCTTGTACAAGCACTGGATCGATGCGGCAGGTGACGATGCA GATGAAATAAACGAACTTCGGGAAGAGTGTGAGGAGCAGGCGAAGTTGATTGAAACAGAGTTTCAAATGGAACGA GACGCGGAATTGGCTCGCGCGCTCCAAGCCGACGAGGATCATAGTCAACTCCCCCGTTCCAATGAGCGTCATACA TGGAATATTCCTGACCGCAGTCAACCGGTAAAACTCGAACATCTTTCATCAAACCCCAATCGTGCACCTCAAGCA TATGCCCCGATAGCCCCATTCAATAAACTCAATCCATTCAATTCCGACGATGATCTTCAAGAAATCACAGCCGAT TCATTCAAAGATCGATCCGGCAAGCAGCCAGCCCGCCCATCCAGTTCATATCCCCACCTGCCATCTCTCCCTTCG CAGTATTCCAAATCACCGTACACTTCACAGGGACTTTATCCCTCGCGGATGCCATATCCCTCCGAGTTGACATAC CCCTCTCAATTGCCATATCCCTCCGAGTTGACATATCCCTCCCAAATGTCATATCCTTCCCAATTGCCGTATCCT TCGCAGCTGGCCTATCCCTCCCAATTGTCAAATTCCTCAATGCCATATTCCACATCAGCAGCTGCCTCCAGAAAC CTTCCCTGGTCGCATGAGCATCCGTACGCTACAATGCCGGGTACATTTGAGAAGTATGACAAATTCGACAAGTTT GACAAGGCCTTTGACCTGGTTCGCAACCAAAGCGAAATATTCGACGACGATGCTGACATAGTGGCCTACAACGAG AAGGAGTTTCCTGAAGATATCAAGAACTTGCTCAGCGGTATCAAAGATATTCGAGAGGCAACTAAAGCGGACAAT GATGAGACACCAAGTGCTCTTCGAGTCACGTTGATGAAGCATCAGAAGATTGGCCTGAGATGGATGAAGGCCAAA GAAGAGAGCAACCACAAAGGAGGAATTCTTGCAGATGACATGGGACTTGGTAAAACCATCCAAGCGATTGCACTG ATGGTTGCTCGCCCATTCGAGGATGAAGACCGACGCCCGACTTTGATTGTCGCGCCCAAGGCACTTATGGATCAA TGGAGACTTGAAATCCAGCGTCATGTCAAGCCGGGCAGGCACCAATTATCAGTCTTGATCTACCATCAACGGCGC AGGCCCTGGAAGGAGCTCAAAAGGTATGATATCATTATCACTACGTTTGGTACAATCACTGCGCACTACAAAACA TTGCTCCAGGCGGAAAAGTTGGCAGAGGAAGGGCGGGATCCCTCGATAATCCAAGACCTCAAAAATGCGGCCGGT CCTCTCAGTCCTGCTGCCAAGTGGCATCGCGTCATCATCGATGAAGCACAGAACATCAAGAACCCAAGTGCGAAA TCGGCAATAGCATGTTGTCGACTCAATGCTACCTACCGCTGGTGTCTGACTGGTACGCCTATGATGAATCGTCTC GAAGATTTCCAGTCCCTTTTGGGATTCCTCCGGATTCGGCCTTATAGCAACCCAGCAAAGTTTAAGGCGGACTTC GTGAGACGCATTAAATCTGGTTGGGGAGGCGAAGATGTCATGAAGCAACTACGCGTTCTAGTCAAGTCTGTCTGT CTCCGACGCACAAAATCCTCCAAGATTGATGGCGAGCCCATCTTGCAACTCCCACCAAAGGTCACCGAGAAGGTC CATGTTGTGTTTGATGAGAGAGAAAGCCAGGTTTATGAGGAACTCAATACGTCCACTCAAAGGCAGATCACCCGG TACCTTGACTCAGGCACGTTGGGCAGGAACTACAGCCATGTTCTAGTTCTCCTTCTCCGTCTTCGGCAGGCATGC TGCCATCCACTTCTCATGCAGGATTTCCGAAACGAACCCTCCCCGTCTATCCCGGGGGTGGATAAGATCGCCAAC GCTAAACTTCTGACCGCTGCTGTAGTGCAACGTATCAAAGATAATGACGGCGAAGAGGATGGCACCTGCCCTGTC TGCATGGACAGTGTCAAAAATGCGACTATTTACATTCCATGTGGACACCATGTGTGCTCGGAGTGCTGGATCCGC ATTTCCGACTCTGCAACTGCAAACGGAGCCATCAACCTCGAAGACGATGGTCCAGCTGTGATTAAGTGCCAGAAC TGCCGAGGGCCCGTGGACCCTGCGAAACTCACCGACACCAATGCATTCAAGCAGGTCCACGATCCAACCTCAGTG CCCGAATTTGCCGCCGGAGGCGGTGATACCAACGGGCCCAATGACGACGAAGACCCAGAAGCAACAGCGAGCAGT GAAGAGTCTGACTCCGATAGCTCTACTGGAGAGGGCGATGCGGAATCAAAGAAGAAAACGAAGGCGAAGTCTCTA GCCCAGCTGCGCAAGGACGCTTTGAGGAACAAGGCCGAGAAGAAGAAATACATTCGCCGCCTCGAGAAGGGCTGG TTCCCCAGCACAAAAATCACAAAGACGCTGGAGATCCTCCAAGCCAATGAAGACCGCGGCTTAGAGGAGAAAACT ATCATTTTCAGCCAGTTCACCTCCCTCTTGGATCTTCTCGAAGTCCCCCTGGCCCGCCGCGGCTGGAACCACACC CGCTTCGACGGCAGCATGAATCTGAAGGAGCGCAACGCCGCTGTGACGGCTTTCACCAATGATCCTGACTGCAAG ATCATGCTCGTCTCCCTCAAGGCCGGCAACTCCGGTCTGAACCTCGTCGCCGCTTCGCATGTCATCATGTTCGAC CCCTTCTGGAACCCGTACATTGAAGACCAGGCCGTTGATCGTGCCCATCGCATCGGGCAGGTTAGAGAGGTCTTC GTTCACCGTCTGCTTATCGAGAATACTGTTGAGGACCGCATTGTTACTCTTCAGGACCAGAAGCGTGAGCTTATC AGTGGTGCTCTCGATGAGGGCGGTACCATGAATGTCTCCCGACTAGATGCGAGGGAACTTGCTTATCTCTTCGGT GTGAGAGACTTGTAA
Transcript	>Pro_DTO377G3_2|g5260.t1 ATGGCTTCTTCGGTCGATCAGTCCCAAGAGGACAAGATCAAAGACCTTTTGGAGGATCTCGATACCTACAGATAC ATATACGATGATCTCCTCGCGACGCGGGGTCCTTGTGCAGAAGCAGATGAGCTTCGTGATACCATCAAAAATATG GAAGTCCAGGTTGCCACGCTCCTTGGTGATCCTGTTCCTACTTCTCAAGCCGCCCCAACACCACAAGTGACATCC CCTACTCCGCCAGTCCGGACGCCTGCGGCTACTCCACGCAAGGCGTCCAACACTTTCACTGGAATCCCCGGGGAT TCATTTGCGTCCCCTCACTGGCCTTCTGCTGCACCCTCACCTTTCGCGGCCGGATCTGGCCAATCGATATTGCTG CCAGCTTCATCAATGATACAGCCTTCTCCAGATAATTCCCGTAAACGCCAGCGTCCGCTATCTCAGGTCTCGCCC ACGATCCAGGGATCATCAAAAAGGATTGCTCCCTCGCAGCCTAAATCTCACAGATCTAAACTCGACGAGATAGAT GCTGCACAAGAAGCCCGCCTTGCCGAGAATCAGCGCTTGTACAAGCACTGGATCGATGCGGCAGGTGACGATGCA GATGAAATAAACGAACTTCGGGAAGAGTGTGAGGAGCAGGCGAAGTTGATTGAAACAGAGTTTCAAATGGAACGA GACGCGGAATTGGCTCGCGCGCTCCAAGCCGACGAGGATCATAGTCAACTCCCCCGTTCCAATGAGCGTCATACA TGGAATATTCCTGACCGCAGTCAACCGGTAAAACTCGAACATCTTTCATCAAACCCCAATCGTGCACCTCAAGCA TATGCCCCGATAGCCCCATTCAATAAACTCAATCCATTCAATTCCGACGATGATCTTCAAGAAATCACAGCCGAT TCATTCAAAGATCGATCCGGCAAGCAGCCAGCCCGCCCATCCAGTTCATATCCCCACCTGCCATCTCTCCCTTCG CAGTATTCCAAATCACCGTACACTTCACAGGGACTTTATCCCTCGCGGATGCCATATCCCTCCGAGTTGACATAC CCCTCTCAATTGCCATATCCCTCCGAGTTGACATATCCCTCCCAAATGTCATATCCTTCCCAATTGCCGTATCCT TCGCAGCTGGCCTATCCCTCCCAATTGTCAAATTCCTCAATGCCATATTCCACATCAGCAGCTGCCTCCAGAAAC CTTCCCTGGTCGCATGAGCATCCGTACGCTACAATGCCGGGTACATTTGAGAAGTATGACAAATTCGACAAGTTT GACAAGGCCTTTGACCTGGTTCGCAACCAAAGCGAAATATTCGACGACGATGCTGACATAGTGGCCTACAACGAG AAGGAGTTTCCTGAAGATATCAAGAACTTGCTCAGCGGTATCAAAGATATTCGAGAGGCAACTAAAGCGGACAAT GATGAGACACCAAGTGCTCTTCGAGTCACGTTGATGAAGCATCAGAAGATTGGCCTGAGATGGATGAAGGCCAAA GAAGAGAGCAACCACAAAGGAGGAATTCTTGCAGATGACATGGGACTTGGTAAAACCATCCAAGCGATTGCACTG ATGGTTGCTCGCCCATTCGAGGATGAAGACCGACGCCCGACTTTGATTGTCGCGCCCAAGGCACTTATGGATCAA TGGAGACTTGAAATCCAGCGTCATGTCAAGCCGGGCAGGCACCAATTATCAGTCTTGATCTACCATCAACGGCGC AGGCCCTGGAAGGAGCTCAAAAGGTATGATATCATTATCACTACGTTTGGTACAATCACTGCGCACTACAAAACA TTGCTCCAGGCGGAAAAGTTGGCAGAGGAAGGGCGGGATCCCTCGATAATCCAAGACCTCAAAAATGCGGCCGGT CCTCTCAGTCCTGCTGCCAAGTGGCATCGCGTCATCATCGATGAAGCACAGAACATCAAGAACCCAAGTGCGAAA TCGGCAATAGCATGTTGTCGACTCAATGCTACCTACCGCTGGTGTCTGACTGGTACGCCTATGATGAATCGTCTC GAAGATTTCCAGTCCCTTTTGGGATTCCTCCGGATTCGGCCTTATAGCAACCCAGCAAAGTTTAAGGCGGACTTC GTGAGACGCATTAAATCTGGTTGGGGAGGCGAAGATGTCATGAAGCAACTACGCGTTCTAGTCAAGTCTGTCTGT CTCCGACGCACAAAATCCTCCAAGATTGATGGCGAGCCCATCTTGCAACTCCCACCAAAGGTCACCGAGAAGGTC CATGTTGTGTTTGATGAGAGAGAAAGCCAGGTTTATGAGGAACTCAATACGTCCACTCAAAGGCAGATCACCCGG TACCTTGACTCAGGCACGTTGGGCAGGAACTACAGCCATGTTCTAGTTCTCCTTCTCCGTCTTCGGCAGGCATGC TGCCATCCACTTCTCATGCAGGATTTCCGAAACGAACCCTCCCCGTCTATCCCGGGGGTGGATAAGATCGCCAAC GCTAAACTTCTGACCGCTGCTGTAGTGCAACGTATCAAAGATAATGACGGCGAAGAGGATGGCACCTGCCCTGTC TGCATGGACAGTGTCAAAAATGCGACTATTTACATTCCATGTGGACACCATGTGTGCTCGGAGTGCTGGATCCGC ATTTCCGACTCTGCAACTGCAAACGGAGCCATCAACCTCGAAGACGATGGTCCAGCTGTGATTAAGTGCCAGAAC TGCCGAGGGCCCGTGGACCCTGCGAAACTCACCGACACCAATGCATTCAAGCAGGTCCACGATCCAACCTCAGTG CCCGAATTTGCCGCCGGAGGCGGTGATACCAACGGGCCCAATGACGACGAAGACCCAGAAGCAACAGCGAGCAGT GAAGAGTCTGACTCCGATAGCTCTACTGGAGAGGGCGATGCGGAATCAAAGAAGAAAACGAAGGCGAAGTCTCTA GCCCAGCTGCGCAAGGACGCTTTGAGGAACAAGGCCGAGAAGAAGAAATACATTCGCCGCCTCGAGAAGGGCTGG TTCCCCAGCACAAAAATCACAAAGACGCTGGAGATCCTCCAAGCCAATGAAGACCGCGGCTTAGAGGAGAAAACT ATCATTTTCAGCCAGTTCACCTCCCTCTTGGATCTTCTCGAAGTCCCCCTGGCCCGCCGCGGCTGGAACCACACC CGCTTCGACGGCAGCATGAATCTGAAGGAGCGCAACGCCGCTGTGACGGCTTTCACCAATGATCCTGACTGCAAG ATCATGCTCGTCTCCCTCAAGGCCGGCAACTCCGGTCTGAACCTCGTCGCCGCTTCGCATGTCATCATGTTCGAC CCCTTCTGGAACCCGTACATTGAAGACCAGGCCGTTGATCGTGCCCATCGCATCGGGCAGGTTAGAGAGGTCTTC GTTCACCGTCTGCTTATCGAGAATACTGTTGAGGACCGCATTGTTACTCTTCAGGACCAGAAGCGTGAGCTTATC AGTGGTGCTCTCGATGAGGGCGGTACCATGAATGTCTCCCGACTAGATGCGAGGGAACTTGCTTATCTCTTCGGT GTGAGAGACTTGTAA
Gene	>Pro_DTO377G3_2|g5260.t1 ATGGCTTCTTCGGTCGATCAGTCCCAAGAGGACAAGATCAAAGACCTTTTGGAGGATCTCGATACCTACAGATAC ATATACGATGATCTCCTCGCGACGCGGGGTCCTTGTGCAGAAGCAGATGAGCTTCGTGATACCATCAAAAATATG GAAGTCCAGGTTGCCACGCTCCTTGGTGATCCTGTTCCTACTTCTCAAGCCGCCCCAACACCACAAGTGACATCC CCTACTCCGCCAGTCCGGACGCCTGCGGCTACTCCACGCAAGGCGTCCAACACTTTCACTGGAATCCCCGGGGAT TCATTTGCGTCCCCTCACTGGCCTTCTGCTGCACCCTCACCTTTCGCGGCCGGATCTGGCCAATCGATATTGCTG CCAGCTTCATCAATGATACAGCCTTCTCCAGATAATTCCCGTAAACGCCAGCGTCCGCTATCTCAGGTCTCGCCC ACGATCCAGGGATCATCAAAAAGGATTGCTCCCTCGCAGCCTAAATCTCACAGATCTAAACTCGACGAGATAGAT GCTGCACAAGAAGCCCGCCTTGCCGAGAATCAGCGCTTGTACAAGCACTGGATCGATGCGGCAGGTGACGATGCA GATGAAATAAACGAACTTCGGGAAGAGTGTGAGGAGCAGGCGAAGTTGATTGAAACAGAGTTTCAAATGGAACGA GACGCGGAATTGGCTCGCGCGCTCCAAGCCGACGAGGATCATAGTCAACTCCCCCGTTCCAATGAGCGTCATACA TGGAATATTCCTGACCGCAGTCAACCGGTAAAACTCGAACATCTTTCATCAAACCCCAATCGTGCACCTCAAGCA TATGCCCCGATAGCCCCATTCAATAAACTCAATCCATTCAATTCCGACGATGATCTTCAAGAAATCACAGCCGAT TCATTCAAAGATCGATCCGGCAAGCAGCCAGCCCGCCCATCCAGTTCATATCCCCACCTGCCATCTCTCCCTTCG CAGTATTCCAAATCACCGTACACTTCACAGGGACTTTATCCCTCGCGGATGCCATATCCCTCCGAGTTGACATAC CCCTCTCAATTGCCATATCCCTCCGAGTTGACATATCCCTCCCAAATGTCATATCCTTCCCAATTGCCGTATCCT TCGCAGCTGGCCTATCCCTCCCAATTGTCAAATTCCTCAATGCCATATTCCACATCAGCAGCTGCCTCCAGAAAC CTTCCCTGGTCGCATGAGCATCCGTACGCTACAATGCCGGGTACATTTGAGAAGTATGACAAATTCGACAAGTTT GACAAGGCCTTTGACCTGGTTCGCAACCAAAGCGAAATATTCGACGACGATGCTGACATAGTGTACGTCCGCATC CTTTGAAGCAGGTAGTTCTGATTCTAACCTCAATTAATATAGGGCCTACAACGAGAAGGAGTTTCCTGAAGATAT CAAGAACTTGCTCAGCGGTATCAAAGATATTCGAGAGGCAACTAAAGCGGACAATGATGAGACACCAAGTGCTCT TCGAGTCACGTTGATGAAGCATCAGAAGATTGGCCTGAGATGGATGAAGGCCAAAGAAGAGAGCAACCACAAAGG AGGAATTCTTGCAGATGACATGGGACTTGGTAAAACCATCCAAGCGATTGCACTGATGGTTGCTCGCCCATTCGA GGATGAAGACCGACGCCCGACTTTGATTGTCGCGCCCAAGGCACTTATGGATCAATGGAGACTTGAAATCCAGCG TCATGTCAAGCCGGGCAGGCACCAATTATCAGTCTTGATCTACCATCAACGGCGCAGGCCCTGGAAGGAGCTCAA AAGGTATGATATCATTATCACTACGTTTGGTACAATCACTGCGCACTACAAAACATTGCTCCAGGCGGAAAAGTT GGCAGAGGAAGGGCGGGATCCCTCGATAATCCAAGACCTCAAAAATGCGGCCGGTCCTCTCAGTCCTGCTGCCAA GTGGCATCGCGTCATCATCGATGAAGCACAGAACATCAAGAACCCAAGTGCGAAATCGGCAATAGCATGTTGTCG ACTCAATGCTACCTACCGCTGGTGTCTGACTGGTACGCCTATGATGAATCGTCTCGAAGATTTCCAGTCCCTTTT GGGATTCCTCCGGATTCGGCCTTATAGCAACCCAGCAAAGTTTAAGGCGGTTAGTACTCTCTATAGTTCACAATT GATGTATGCTTCTTTGGCTGACTGACATTTATATCTATCCAGGACTTCGTGAGACGCATTAAATCTGGTTGGGGA GGCGAAGATGTCATGAAGCAACTACGCGTTCTAGTCAAGTCTGTCTGTCTCCGACGCACAAAATCCTCCAAGATT GATGGCGAGCCCATCTTGCAACTCCCACCAAAGGTCACCGAGAAGGTCCATGTTGTGTTTGATGAGAGAGAAAGC CAGGTTTATGAGGAACTCAATACGTCCACTCAAAGGCAGATCACCCGGTACCTTGACTCAGGCACGTTGGGCAGG AACTACAGCCATGTTCTAGTTCTCCTTCTCCGTCTTCGGCAGGCATGCTGCCATCCACTTCTCATGCAGGATTTC CGAAACGAACCCTCCCCGTCTATCCCGGGGGTGGATAAGATCGCCAACGCTAAACTTCTGACCGCTGCTGTAGTG CAACGTATCAAAGATAATGACGGCGAAGAGGATGGCACCTGCCCTGTCTGCATGGACAGTGTCAAAAATGCGACT ATTTACATTCCATGTGGACACCATGTGTGCTCGGAGTGCTGGATCCGCATTTCCGACTCTGCAACTGCAAACGGA GCCATCAACCTCGAAGACGATGGTCCAGCTGTGATTAAGTGCCAGAACTGCCGAGGGCCCGTGGACCCTGCGAAA CTCACCGACACCAATGCATTCAAGCAGGTCCACGATCCAACCTCAGTGCCCGAATTTGCCGCCGGAGGCGGTGAT ACCAACGGGCCCAATGACGACGAAGACCCAGAAGCAACAGCGAGCAGTGAAGAGTCTGACTCCGATAGCTCTACT GGAGAGGGCGATGCGGAATCAAAGAAGAAAACGAAGGCGAAGTCTCTAGCCCAGCTGCGCAAGGACGCTTTGAGG AACAAGGCCGAGAAGAAGAAATACATTCGCCGCCTCGAGAAGGGCTGGTTCCCCAGCACAAAAATCACAAAGACG CTGGAGATCCTCCAAGCCAATGAAGACCGCGGCTTAGAGGAGAAAACTATCATTTTCAGCCAGTTCACCTCCCTC TTGGATCTTCTCGAAGTCCCCCTGGCCCGCCGCGGCTGGAACCACACCCGCTTCGACGGCAGCATGAATCTGAAG GAGCGCAACGCCGCTGTGACGGCTTTCACCAATGATCCTGACTGCAAGATCATGCTCGTCTCCCTCAAGGCCGGC AACTCCGGTCTGAACCTCGTCGCCGCTTCGCATGTCATCATGTTCGACCCCTTCTGGAACCCGTACATTGAAGAC CAGGCCGTTGATCGTGCCCATCGCATCGGGCAGGTTAGAGAGGTCTTCGTTCACCGTCTGCTTATCGAGAATACT GTTGAGGACCGCATTGTTACTCTTCAGGACCAGAAGCGTGAGCTTATCAGTGGTGCTCTCGATGAGGGCGGTACC ATGAATGTCTCCCGACTAGATGCGAGGGAACTTGCTTATCTCTTCGTATGTTTATCCCTATTTTCCTCGTTTTCT ACTTTGACTGGACTCTTTGCTAACTCCTTATCCGTTACACAGGGTGTGAGAGACTTGTAA