Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g5173.t1
Gene name
Location	scaffold_12:97622..101494
Strand	+
Gene length (bp)	3872
Transcript length (bp)	3825
Coding sequence length (bp)	3825
Protein length (aa)	1275

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF02538	Hydantoinase_B	Hydantoinase B/oxoprolinase	7.1E-213	736	1273
PF01968	Hydantoinase_A	Hydantoinase/oxoprolinase	9.2E-102	234	534
PF05378	Hydant_A_N	Hydantoinase/oxoprolinase N-terminal region	8.7E-56	9	216
PF19278	Hydant_A_C	Hydantoinase/oxoprolinase C-terminal domain	7.8E-07	547	720

GO

GO Term	Description	Terminal node
GO:0003824	catalytic activity	Yes
GO:0016787	hydrolase activity	Yes
GO:0003674	molecular_function	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 23	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g5173.t1 MSDSGKITISIDRGGTFTDVHAIQPGRPDIILKLLSVDPSHYQDAPTEGIRRILELATGEPHPRGQPLRLDRIGC LRMGTTVATNALLERKGARSALFTTKGFRDLLKIGDQSRPAIFDLSMARPGVLPESVVEVNERVLSCHPSADSAC FSDCRLVEGITGENFRVVQELDLVQVKAELQRLKEQGILSISVALLHSYAYPEHERQIGELAQEMGFSVTLSSNL QPMIKIVPRGMSAAADAYLTPVIKTYIDSISSSFEGGLESQQKCRFEFMQSDGGLVDFRKFSGLKAILSGPAAGV VGFAATSWDPTEKTPVIGFDMGGTSTDVSRFDGHFEHVFASKVAGVIIQSPQLDINTVAAGGGSILTWRNGLFYV GPESASAHPGPACYRKGGPLTVTDANLFLGRLLPEHFPKIFGPNENEALDTETTARLFNELTQKVNIERRQQGQS EFSPEEIALGFLHVADESMSRPIRNLTEARGFETASHHLACFGGAGGQHACSVAKTLGISRIIIHKYSSVLSAYG LALAEVVKESQEPVSSAYLSSQSTLLQRLDNLSASATKDMESQGFPSTQVRHEQYLNMRYEGSDTSLMIRKPENS DFLEAFRIRHRREFNFNSDRPVLVDDVRVRTIASSKVRTEQSPLVQLKEADLRDVAPALNTTSAYFGQLGRVDTP VYLLGALEKNSRIHGPAIIIDQTQTIVVAPNAVANLLDTCIVIDLNDEPTSSGSALSSEIDPIRLTIFGHRFMSI AEQMGHTLQKTSVSTNIKERLDFSCALFSPDGGLVANAPHVPVHLGSMQFAVRYQHEKWLGNLKDGDVLVANHPS CGGTHLPDITVITPVFDRPGGSEIMFYVASRGHHADIGGILPGSMPPKSTELWQEGAAIEGDKIVSDGILDEARL IELLVTKPSKYPGCVGARCISDNLSDLKAQIAANTRGISLIQTLFNEYGTQTVQKYMYAIQATAEAAVRNLLKEL YQKFNGQPLESVDYMDDGTPIRLKVTINGAEGSAIFDFEGTGPEVYGSWNAPIAITHSAIIYCLRCMINADVPLN QGCLAPIDIRVPSSSILSPSKTAAVVGGNVVTSQRITDVVFKAFQACAASQGCCNNLTFGRDAKLDSSTGAVITP GFGYYETIAGGSGAGPTWRGESGIQVHMTNTRITDPEILEKRYPTMLRQFALREGSGGQGRNPGGEGVIRDIEFL SPIQCSILSERRVHRPYGLEGGQDAQTGFNLWITRDPDTGNERRINIGGKNTVSMKTHDRVVINTPGGGGWGAV*
Coding	>Pro_DTO377G3_2|g5173.t1 ATGTCTGACTCAGGGAAGATCACCATCTCCATCGATCGTGGCGGCACATTTACTGATGTCCACGCGATTCAACCT GGCCGTCCCGACATTATCTTGAAGCTTCTCTCTGTCGATCCTTCTCATTACCAAGATGCCCCGACTGAGGGTATC CGTCGGATTCTAGAGCTTGCCACCGGGGAACCACACCCCCGAGGCCAACCATTGAGACTCGACCGTATTGGTTGC CTCCGCATGGGCACAACCGTTGCAACCAATGCCTTACTCGAGCGCAAGGGTGCCCGCTCAGCACTCTTCACGACG AAAGGGTTTCGAGATTTACTGAAAATTGGCGACCAATCTCGCCCGGCCATTTTTGACCTATCAATGGCTCGGCCC GGAGTACTCCCGGAGAGTGTCGTCGAAGTCAACGAACGTGTGCTGTCGTGCCATCCTTCTGCTGATAGCGCTTGC TTCTCCGATTGCCGCTTAGTAGAAGGAATCACCGGCGAGAATTTCCGCGTGGTGCAAGAACTAGACCTCGTTCAG GTGAAGGCAGAGCTCCAACGACTAAAGGAGCAAGGAATTCTGTCAATCTCTGTGGCGCTACTGCATTCTTACGCA TATCCTGAGCACGAGCGTCAAATCGGCGAGCTCGCTCAAGAGATGGGATTCTCGGTCACTCTCTCTTCAAACCTT CAACCCATGATCAAGATCGTGCCTCGTGGCATGTCGGCCGCTGCTGATGCCTATCTTACACCTGTTATCAAGACA TATATTGACTCTATCTCTTCCAGTTTTGAAGGTGGGTTGGAGAGTCAACAGAAATGCCGATTTGAGTTCATGCAG TCAGATGGTGGACTGGTTGATTTCCGCAAATTCAGCGGGCTGAAAGCGATTTTGTCCGGCCCCGCAGCTGGTGTG GTTGGCTTTGCAGCCACTAGCTGGGATCCCACCGAGAAGACTCCCGTCATTGGTTTCGATATGGGTGGTACTAGC ACAGATGTCTCCAGATTCGATGGCCACTTTGAGCATGTATTTGCCTCTAAGGTTGCAGGTGTGATAATCCAGTCC CCTCAACTTGATATTAACACTGTTGCTGCTGGCGGCGGCTCCATCCTCACTTGGCGTAATGGCTTGTTTTATGTC GGGCCTGAGTCAGCAAGTGCTCATCCTGGTCCGGCATGCTACCGTAAGGGTGGCCCTCTTACAGTGACAGACGCC AATCTGTTCCTAGGTCGCCTTCTGCCCGAGCACTTCCCGAAGATCTTCGGGCCGAATGAGAATGAAGCTCTAGAT ACAGAGACGACTGCACGCCTTTTCAATGAACTCACACAGAAAGTCAACATTGAACGCCGGCAGCAAGGCCAGTCG GAATTTTCCCCAGAGGAGATTGCACTTGGTTTCCTTCATGTGGCCGATGAATCTATGTCCCGGCCAATCCGTAAC CTCACGGAGGCTCGTGGCTTTGAGACAGCATCTCATCATTTGGCATGCTTCGGAGGTGCTGGTGGCCAGCACGCA TGCTCAGTGGCCAAAACGCTCGGAATATCCCGCATCATCATTCATAAGTATTCTTCCGTTCTATCAGCATACGGC CTTGCTCTGGCAGAAGTTGTCAAGGAGTCTCAGGAACCTGTTTCGTCAGCCTACCTATCTTCACAATCTACACTT CTTCAACGCCTCGATAACTTGTCAGCATCAGCAACCAAAGATATGGAATCTCAAGGTTTCCCCTCCACTCAAGTG CGCCATGAGCAGTACTTGAACATGCGCTACGAAGGTTCTGATACCAGTCTAATGATCCGGAAGCCCGAGAACTCA GACTTCCTGGAAGCATTCCGCATTCGTCATCGCCGGGAATTCAACTTCAACTCTGACCGACCTGTCCTTGTTGAT GACGTTCGAGTACGAACAATCGCCTCTTCCAAGGTGCGGACTGAGCAAAGTCCCTTGGTTCAACTGAAAGAAGCC GATCTGCGAGATGTCGCGCCGGCTTTAAATACCACTTCAGCCTACTTTGGCCAGTTGGGTCGGGTGGATACACCA GTTTACCTTCTCGGTGCATTGGAGAAGAATTCCCGCATTCATGGCCCGGCTATCATTATTGATCAAACCCAAACA ATTGTCGTGGCTCCCAACGCAGTGGCGAACCTGCTCGATACCTGCATTGTCATCGATCTCAATGACGAACCAACC TCATCTGGAAGCGCCCTGTCATCGGAAATTGACCCCATCAGGCTTACCATCTTTGGACATCGGTTCATGTCTATC GCTGAGCAGATGGGTCATACGCTACAGAAAACCTCCGTTTCAACTAACATCAAGGAGCGGCTAGATTTCTCTTGT GCTCTATTCTCCCCCGACGGAGGTTTGGTTGCCAATGCACCCCATGTTCCGGTTCATCTTGGATCTATGCAATTT GCCGTGCGTTATCAGCATGAGAAGTGGCTAGGCAACCTGAAGGATGGTGATGTTCTGGTGGCCAATCACCCCAGT TGTGGAGGCACCCATCTGCCCGATATCACAGTCATTACACCGGTCTTTGACCGACCTGGTGGCTCCGAGATCATG TTTTACGTGGCTTCCCGTGGACATCACGCTGACATTGGCGGTATATTACCTGGATCAATGCCTCCCAAATCCACC GAACTGTGGCAAGAAGGCGCCGCCATCGAAGGTGATAAGATTGTCAGTGATGGTATCTTAGATGAGGCACGGTTG ATCGAGTTGCTGGTCACAAAGCCCTCGAAATATCCCGGCTGCGTTGGAGCACGCTGCATTAGCGACAACTTGTCT GATCTGAAGGCACAGATTGCCGCCAACACTCGTGGAATCAGCTTGATTCAAACTCTGTTTAACGAATATGGAACT CAGACCGTGCAAAAGTACATGTACGCCATCCAGGCAACCGCCGAGGCTGCGGTGCGCAATCTTCTCAAGGAACTA TATCAGAAGTTCAATGGCCAGCCATTGGAGTCAGTCGACTACATGGATGACGGTACCCCCATCCGATTGAAGGTC ACCATCAACGGTGCCGAGGGATCAGCCATCTTCGACTTCGAGGGTACAGGCCCTGAGGTTTATGGTAGCTGGAAC GCTCCTATTGCCATTACTCACTCGGCTATTATCTACTGTTTACGGTGTATGATCAATGCAGACGTGCCACTGAAC CAGGGATGCTTGGCGCCAATTGACATTCGTGTTCCATCGTCCAGCATTTTGTCACCGAGCAAGACTGCTGCCGTC GTTGGTGGCAACGTTGTGACCTCACAGCGCATTACTGACGTCGTGTTCAAAGCCTTCCAGGCTTGTGCCGCGTCT CAAGGCTGCTGTAACAACCTGACCTTCGGTAGAGACGCCAAGCTCGATTCGTCCACCGGTGCTGTCATCACACCT GGATTTGGATATTACGAGACTATCGCGGGTGGCAGTGGTGCTGGCCCAACTTGGAGGGGTGAGTCTGGTATACAA GTTCATATGACCAACACGCGGATCACCGATCCTGAAATCCTGGAAAAGCGCTATCCGACGATGCTCCGTCAGTTC GCTCTACGTGAGGGCTCTGGCGGCCAGGGTAGGAACCCCGGTGGCGAGGGAGTGATTCGCGACATCGAGTTCCTT TCACCAATCCAATGTTCGATTCTGTCTGAGCGCCGTGTCCATCGGCCTTACGGACTGGAAGGTGGCCAGGATGCA CAGACCGGGTTCAATCTGTGGATCACGCGGGATCCAGATACTGGCAATGAGCGCCGTATTAACATTGGCGGCAAG AACACCGTCTCAATGAAGACACACGACCGGGTTGTGATCAACACTCCGGGTGGTGGTGGCTGGGGGGCTGTATGA
Transcript	>Pro_DTO377G3_2|g5173.t1 ATGTCTGACTCAGGGAAGATCACCATCTCCATCGATCGTGGCGGCACATTTACTGATGTCCACGCGATTCAACCT GGCCGTCCCGACATTATCTTGAAGCTTCTCTCTGTCGATCCTTCTCATTACCAAGATGCCCCGACTGAGGGTATC CGTCGGATTCTAGAGCTTGCCACCGGGGAACCACACCCCCGAGGCCAACCATTGAGACTCGACCGTATTGGTTGC CTCCGCATGGGCACAACCGTTGCAACCAATGCCTTACTCGAGCGCAAGGGTGCCCGCTCAGCACTCTTCACGACG AAAGGGTTTCGAGATTTACTGAAAATTGGCGACCAATCTCGCCCGGCCATTTTTGACCTATCAATGGCTCGGCCC GGAGTACTCCCGGAGAGTGTCGTCGAAGTCAACGAACGTGTGCTGTCGTGCCATCCTTCTGCTGATAGCGCTTGC TTCTCCGATTGCCGCTTAGTAGAAGGAATCACCGGCGAGAATTTCCGCGTGGTGCAAGAACTAGACCTCGTTCAG GTGAAGGCAGAGCTCCAACGACTAAAGGAGCAAGGAATTCTGTCAATCTCTGTGGCGCTACTGCATTCTTACGCA TATCCTGAGCACGAGCGTCAAATCGGCGAGCTCGCTCAAGAGATGGGATTCTCGGTCACTCTCTCTTCAAACCTT CAACCCATGATCAAGATCGTGCCTCGTGGCATGTCGGCCGCTGCTGATGCCTATCTTACACCTGTTATCAAGACA TATATTGACTCTATCTCTTCCAGTTTTGAAGGTGGGTTGGAGAGTCAACAGAAATGCCGATTTGAGTTCATGCAG TCAGATGGTGGACTGGTTGATTTCCGCAAATTCAGCGGGCTGAAAGCGATTTTGTCCGGCCCCGCAGCTGGTGTG GTTGGCTTTGCAGCCACTAGCTGGGATCCCACCGAGAAGACTCCCGTCATTGGTTTCGATATGGGTGGTACTAGC ACAGATGTCTCCAGATTCGATGGCCACTTTGAGCATGTATTTGCCTCTAAGGTTGCAGGTGTGATAATCCAGTCC CCTCAACTTGATATTAACACTGTTGCTGCTGGCGGCGGCTCCATCCTCACTTGGCGTAATGGCTTGTTTTATGTC GGGCCTGAGTCAGCAAGTGCTCATCCTGGTCCGGCATGCTACCGTAAGGGTGGCCCTCTTACAGTGACAGACGCC AATCTGTTCCTAGGTCGCCTTCTGCCCGAGCACTTCCCGAAGATCTTCGGGCCGAATGAGAATGAAGCTCTAGAT ACAGAGACGACTGCACGCCTTTTCAATGAACTCACACAGAAAGTCAACATTGAACGCCGGCAGCAAGGCCAGTCG GAATTTTCCCCAGAGGAGATTGCACTTGGTTTCCTTCATGTGGCCGATGAATCTATGTCCCGGCCAATCCGTAAC CTCACGGAGGCTCGTGGCTTTGAGACAGCATCTCATCATTTGGCATGCTTCGGAGGTGCTGGTGGCCAGCACGCA TGCTCAGTGGCCAAAACGCTCGGAATATCCCGCATCATCATTCATAAGTATTCTTCCGTTCTATCAGCATACGGC CTTGCTCTGGCAGAAGTTGTCAAGGAGTCTCAGGAACCTGTTTCGTCAGCCTACCTATCTTCACAATCTACACTT CTTCAACGCCTCGATAACTTGTCAGCATCAGCAACCAAAGATATGGAATCTCAAGGTTTCCCCTCCACTCAAGTG CGCCATGAGCAGTACTTGAACATGCGCTACGAAGGTTCTGATACCAGTCTAATGATCCGGAAGCCCGAGAACTCA GACTTCCTGGAAGCATTCCGCATTCGTCATCGCCGGGAATTCAACTTCAACTCTGACCGACCTGTCCTTGTTGAT GACGTTCGAGTACGAACAATCGCCTCTTCCAAGGTGCGGACTGAGCAAAGTCCCTTGGTTCAACTGAAAGAAGCC GATCTGCGAGATGTCGCGCCGGCTTTAAATACCACTTCAGCCTACTTTGGCCAGTTGGGTCGGGTGGATACACCA GTTTACCTTCTCGGTGCATTGGAGAAGAATTCCCGCATTCATGGCCCGGCTATCATTATTGATCAAACCCAAACA ATTGTCGTGGCTCCCAACGCAGTGGCGAACCTGCTCGATACCTGCATTGTCATCGATCTCAATGACGAACCAACC TCATCTGGAAGCGCCCTGTCATCGGAAATTGACCCCATCAGGCTTACCATCTTTGGACATCGGTTCATGTCTATC GCTGAGCAGATGGGTCATACGCTACAGAAAACCTCCGTTTCAACTAACATCAAGGAGCGGCTAGATTTCTCTTGT GCTCTATTCTCCCCCGACGGAGGTTTGGTTGCCAATGCACCCCATGTTCCGGTTCATCTTGGATCTATGCAATTT GCCGTGCGTTATCAGCATGAGAAGTGGCTAGGCAACCTGAAGGATGGTGATGTTCTGGTGGCCAATCACCCCAGT TGTGGAGGCACCCATCTGCCCGATATCACAGTCATTACACCGGTCTTTGACCGACCTGGTGGCTCCGAGATCATG TTTTACGTGGCTTCCCGTGGACATCACGCTGACATTGGCGGTATATTACCTGGATCAATGCCTCCCAAATCCACC GAACTGTGGCAAGAAGGCGCCGCCATCGAAGGTGATAAGATTGTCAGTGATGGTATCTTAGATGAGGCACGGTTG ATCGAGTTGCTGGTCACAAAGCCCTCGAAATATCCCGGCTGCGTTGGAGCACGCTGCATTAGCGACAACTTGTCT GATCTGAAGGCACAGATTGCCGCCAACACTCGTGGAATCAGCTTGATTCAAACTCTGTTTAACGAATATGGAACT CAGACCGTGCAAAAGTACATGTACGCCATCCAGGCAACCGCCGAGGCTGCGGTGCGCAATCTTCTCAAGGAACTA TATCAGAAGTTCAATGGCCAGCCATTGGAGTCAGTCGACTACATGGATGACGGTACCCCCATCCGATTGAAGGTC ACCATCAACGGTGCCGAGGGATCAGCCATCTTCGACTTCGAGGGTACAGGCCCTGAGGTTTATGGTAGCTGGAAC GCTCCTATTGCCATTACTCACTCGGCTATTATCTACTGTTTACGGTGTATGATCAATGCAGACGTGCCACTGAAC CAGGGATGCTTGGCGCCAATTGACATTCGTGTTCCATCGTCCAGCATTTTGTCACCGAGCAAGACTGCTGCCGTC GTTGGTGGCAACGTTGTGACCTCACAGCGCATTACTGACGTCGTGTTCAAAGCCTTCCAGGCTTGTGCCGCGTCT CAAGGCTGCTGTAACAACCTGACCTTCGGTAGAGACGCCAAGCTCGATTCGTCCACCGGTGCTGTCATCACACCT GGATTTGGATATTACGAGACTATCGCGGGTGGCAGTGGTGCTGGCCCAACTTGGAGGGGTGAGTCTGGTATACAA GTTCATATGACCAACACGCGGATCACCGATCCTGAAATCCTGGAAAAGCGCTATCCGACGATGCTCCGTCAGTTC GCTCTACGTGAGGGCTCTGGCGGCCAGGGTAGGAACCCCGGTGGCGAGGGAGTGATTCGCGACATCGAGTTCCTT TCACCAATCCAATGTTCGATTCTGTCTGAGCGCCGTGTCCATCGGCCTTACGGACTGGAAGGTGGCCAGGATGCA CAGACCGGGTTCAATCTGTGGATCACGCGGGATCCAGATACTGGCAATGAGCGCCGTATTAACATTGGCGGCAAG AACACCGTCTCAATGAAGACACACGACCGGGTTGTGATCAACACTCCGGGTGGTGGTGGCTGGGGGGCTGTATGA
Gene	>Pro_DTO377G3_2|g5173.t1 ATGTCTGACTCAGGGAAGATCACCATCTCCATCGATCGTGGCGGCACATTTACTGATGTCCACGCGATTCAACCT GGCCGTCCCGACATTATCTTGAAGCTTCTCTCTGTCGATCCTTCTCATTACCAAGATGCCCCGACTGAGGGTATC CGTCGGATTCTAGAGCTTGCCACCGGGGAACCACACCCCCGAGGCCAACCATTGAGACTCGACCGTATTGGTTGC CTCCGCATGGGCACAACCGTTGCAACCAATGCCTTACTCGAGCGCAAGGGTGCCCGCTCAGCACTCTTCACGACG AAAGGGTTTCGAGATTTACTGAAAATTGGCGACCAATCTCGCCCGGCCATTTTTGACCTATCAATGGCTCGGCCC GGAGTACTCCCGGAGAGTGTCGTCGAAGTCAACGAACGTGTGCTGTCGTGCCATCCTTCTGCTGATAGCGCTTGC TTCTCCGATTGCCGCTTAGTAGAAGGAATCACCGGCGAGAATTTCCGCGTGGTGCAAGAACTAGACCTCGTTCAG GTGAAGGCAGAGCTCCAACGACTAAAGGAGCAAGGAATTCTGTCAATCTCTGTGGCGCTACTGCATTCTTACGCA TATCCTGAGCACGAGCGTCAAATCGGCGAGCTCGCTCAAGAGATGGGATTCTCGGTCACTCTCTCTTCAAACCTT CAACCCATGATCAAGATCGTGCCTCGTGGCATGTCGGCCGCTGCTGATGCCTATCTTACACCTGTTATCAAGACA TATATTGACTCTATCTCTTCCAGTTTTGAAGGTGGGTTGGAGAGTCAACAGAAATGCCGATTTGAGTTCATGCAG TCAGATGGTGGACTGGTTGATTTCCGCAAATTCAGCGGGCTGAAAGCGATTTTGTCCGGCCCCGCAGCTGGTGTG GTTGGCTTTGCAGCCACTAGCTGGGATCCCACCGAGAAGACTCCCGTCATTGGTTTCGATATGGGTGGTACTAGC ACAGATGTCTCCAGATTCGATGGCCACTTTGAGCATGTATTTGCCTCTAAGGTTGCAGGTGTGATAATCCAGTCC CCTCAACTTGATATTAACACTGTTGCTGCTGGCGGCGGCTCCATCCTCACTTGGCGTAATGGCTTGTTTTATGTC GGGCCTGAGTCAGCAAGTGCTCATCCTGGTCCGGCATGCTACCGTAAGGGTGGCCCTCTTACAGTGACAGACGCC AATCTGTTCCTAGGTCGCCTTCTGCCCGAGCACTTCCCGAAGATCTTCGGGCCGAATGAGAATGAAGCTCTAGAT ACAGAGACGACTGCACGCCTTTTCAATGAACTCACACAGAAAGTCAACATTGAACGCCGGCAGCAAGGCCAGTCG GAATTTTCCCCAGAGGAGATTGCACTTGGTTTCCTTCATGTGGCCGATGAATCTATGTCCCGGCCAATCCGTAAC CTCACGGAGGCTCGTGGCTTTGAGACAGCATCTCATCATTTGGCATGCTTCGGAGGTGCTGGTGGCCAGCACGCA TGCTCAGTGGCCAAAACGCTCGGAATATCCCGCATCATCATTCATAAGTATTCTTCCGTTCTATCAGCATACGGC CTTGCTCTGGCAGAAGTTGTCAAGGAGTCTCAGGAACCTGTTTCGTCAGCCTACCTATCTTCACAATCTACACTT CTTCAACGCCTCGATAACTTGTCAGCATCAGCAACCAAAGATATGGAATCTCAAGGTTTCCCCTCCACTCAAGTG CGCCATGAGCAGTACTTGAACATGCGCTACGAAGGTTCTGATACCAGTCTAATGATCCGGAAGCCCGAGAACTCA GACTTCCTGGAAGCATTCCGCATTCGTCATCGCCGGGAATTCAACTTCAACTCTGACCGACCTGTCCTTGTTGAT GACGTTCGAGTACGAACAATCGCCTCTTCCAAGGTGCGGACTGAGCAAAGTCCCTTGGTTCAACTGAAAGAAGCC GATCTGCGAGATGTCGCGCCGGCTTTAAATACCACTTCAGCCTACTTTGGCCAGTTGGGTCGGGTGGATACACCA GTTTACCTTCTCGGTGCATTGGAGAAGAATTCCCGCATTCATGGCCCGGCTATCATTATTGATCAAACCCAAACA ATTGTCGTGGCTCCCAACGCAGTGGCGAACCTGCTCGATACCTGCATTGTCATCGATCTCAATGACGAACCAACC TCATCTGGAAGCGCCCTGTCATCGGAAATTGACCCCATCAGGCTTACCATCTTTGGACATCGGTTCATGTCTATC GCTGAGCAGATGGGTCATACGCTACAGAAAACCTCCGTTTCAACTAACATCAAGGAGCGGCTAGATTTCTCTTGT GCTCTATTCTCCCCCGACGGAGGTTTGGTTGCCAATGCACCCCATGTTCCGGTTCATCTTGGATCTATGCAATTT GCCGTGCGTTATCAGCATGAGAAGTGGCTAGGCAACCTGAAGGATGGTGATGTTCTGGTGGCCAATCACCCCAGT TGTGGAGGCACCCATCTGCCCGATATCACAGTAAGTCACCTTCATATTGACTACATCGAATACTAATATATCTAT AGGTCATTACACCGGTCTTTGACCGACCTGGTGGCTCCGAGATCATGTTTTACGTGGCTTCCCGTGGACATCACG CTGACATTGGCGGTATATTACCTGGATCAATGCCTCCCAAATCCACCGAACTGTGGCAAGAAGGCGCCGCCATCG AAGGTGATAAGATTGTCAGTGATGGTATCTTAGATGAGGCACGGTTGATCGAGTTGCTGGTCACAAAGCCCTCGA AATATCCCGGCTGCGTTGGAGCACGCTGCATTAGCGACAACTTGTCTGATCTGAAGGCACAGATTGCCGCCAACA CTCGTGGAATCAGCTTGATTCAAACTCTGTTTAACGAATATGGAACTCAGACCGTGCAAAAGTACATGTACGCCA TCCAGGCAACCGCCGAGGCTGCGGTGCGCAATCTTCTCAAGGAACTATATCAGAAGTTCAATGGCCAGCCATTGG AGTCAGTCGACTACATGGATGACGGTACCCCCATCCGATTGAAGGTCACCATCAACGGTGCCGAGGGATCAGCCA TCTTCGACTTCGAGGGTACAGGCCCTGAGGTTTATGGTAGCTGGAACGCTCCTATTGCCATTACTCACTCGGCTA TTATCTACTGTTTACGGTGTATGATCAATGCAGACGTGCCACTGAACCAGGGATGCTTGGCGCCAATTGACATTC GTGTTCCATCGTCCAGCATTTTGTCACCGAGCAAGACTGCTGCCGTCGTTGGTGGCAACGTTGTGACCTCACAGC GCATTACTGACGTCGTGTTCAAAGCCTTCCAGGCTTGTGCCGCGTCTCAAGGCTGCTGTAACAACCTGACCTTCG GTAGAGACGCCAAGCTCGATTCGTCCACCGGTGCTGTCATCACACCTGGATTTGGATATTACGAGACTATCGCGG GTGGCAGTGGTGCTGGCCCAACTTGGAGGGGTGAGTCTGGTATACAAGTTCATATGACCAACACGCGGATCACCG ATCCTGAAATCCTGGAAAAGCGCTATCCGACGATGCTCCGTCAGTTCGCTCTACGTGAGGGCTCTGGCGGCCAGG GTAGGAACCCCGGTGGCGAGGGAGTGATTCGCGACATCGAGTTCCTTTCACCAATCCAATGTTCGATTCTGTCTG AGCGCCGTGTCCATCGGCCTTACGGACTGGAAGGTGGCCAGGATGCACAGACCGGGTTCAATCTGTGGATCACGC GGGATCCAGATACTGGCAATGAGCGCCGTATTAACATTGGCGGCAAGAACACCGTCTCAATGAAGACACACGACC GGGTTGTGATCAACACTCCGGGTGGTGGTGGCTGGGGGGCTGTATGA