Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g5036.t1
Gene name
Location	scaffold_11:383192..387068
Strand	-
Gene length (bp)	3876
Transcript length (bp)	3267
Coding sequence length (bp)	3267
Protein length (aa)	1089

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00169	PH	PH domain	4.2E-10	825	972
PF07647	SAM_2	SAM domain (Sterile alpha motif)	3.9E-08	333	397
PF14604	SH3_9	Variant SH3 domain	2.8E-07	114	167
PF00018	SH3_1	SH3 domain	2.1E-06	114	163

GO

GO Term	Description	Terminal node
GO:0005515	protein binding	Yes
GO:0005488	binding	No
GO:0003674	molecular_function	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 22	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g5036.t1 MFAIAILYSIPLDLNLNCATSQLLSLNHGKVSQVQTFLQSHTSLSPFSSNLRLRNPIYLYKVEILPFGLLTFSPL SLTLPPNHITPESPPDTRNIKMVTMGPPKGVRPGDILEVLHEFGGRGEDELVMLPRDKIKLIELDEEFGDAWYYG QNLRTGQTGLFPANFTKVGSPRKTLAESPVLVESPIQLESLARPDSSFASAESGQSTPQASRHVSSDDMQSPQIS SPTQHRSASSPLPRPSLAADIQQAFRGSIDNHLNGEESPVMNETLSVIDEHITDMNTPRHSVSTQEPRTINDSGS EYSSHIGHRASYINGNETDDEEQSLPTEQEVRKWSPTQTSRCLRSLGIDQKHCDIFEEQEITGDVLLDMDQDFIF MKEFDFGVMGRRLKTWHKVKAFQEETKGFSQQQAPRGSISSNFSPSDERALSRAGHTGPLLPRIPTLSEKTGAGY PRGSVPVQHPRLASNSSSPMTPHTPPYSHESTRRISAASLRDLNQARRHSSIDATQRGMPDSGFVGHQQKKPSFD RSWTLNSGPQAMPARPGTSAGTSPGGFRNGPLTAESDSYNSYVTTPDQIEDLDRGYFSGTEVDSRRARRVLQKRG SAGVDVNNQSRKSSYADDSYQVISPAKRHSRIGSVDSIRDAANRVSPAAKAYHGTPPKSRLRSLSTRVLTDKSGT SSQSSTTDSKTSNGGGFFANFSRVGGKGDSEIPRASPLQFQPLKNAGPKFRRAMGLRAISDVAGKKLDTSALPDS PLESDPTSARTGSTTPSATSKSSERHSTDGSGKATTDGQGFVARPRTAKSKKETSAYTRGLEKKTPQEQMDGCDY SGWMKKRSSNLMTTWKPRLFVLRGRRLSYYYSEDDTEERGLIDITAHRVLRADQDPIIALHATITGSTALPANAN NTVDSPSGTKLTTPSVIQSLTTKDGSGPFFFKLVPPKSGNSRTVQFTKPATHFFQVDNVQQGRLWMGALMKATIE RDLGQAVETTNKQKTISLKQARLLQQRPADLVPASGSTKTAQTIDEEEEEAGLQIEGLNLSQSDVNSLEDTNGSI DINNTDEGLERPISNPLGDLDNGQSSLLPDPLAKTESK*
Coding	>Pro_DTO377G3_2|g5036.t1 ATGTTTGCTATAGCTATCCTATACTCGATTCCTCTGGATCTGAATCTCAATTGTGCCACCTCTCAGCTCCTCTCC CTCAACCACGGGAAAGTCTCCCAAGTCCAGACTTTCTTACAATCGCACACGTCACTCTCGCCTTTCTCTTCGAAT TTGCGTCTTAGAAATCCAATCTATCTCTACAAGGTCGAGATCCTTCCCTTTGGACTTCTCACATTCTCTCCCCTT TCTCTTACCCTTCCGCCAAATCACATTACTCCCGAGTCTCCCCCAGATACACGGAATATTAAGATGGTTACCATG GGCCCACCGAAGGGTGTTCGTCCAGGCGACATTCTGGAGGTTCTTCATGAATTTGGCGGGCGCGGAGAAGACGAA CTGGTCATGTTACCCCGCGACAAGATTAAACTGATCGAGTTGGATGAGGAATTTGGAGATGCCTGGTACTACGGA CAGAACCTGAGGACGGGACAAACTGGTCTCTTCCCTGCAAACTTTACCAAAGTGGGCTCCCCAAGAAAGACCCTC GCCGAGTCGCCAGTTCTGGTAGAATCGCCGATCCAATTGGAATCCCTCGCGCGCCCAGATTCATCATTCGCATCG GCTGAGAGTGGACAGAGCACCCCTCAAGCATCGCGCCACGTTAGCTCCGACGATATGCAGTCACCGCAAATCAGT TCTCCCACACAGCATCGATCCGCCTCGTCTCCGCTGCCTCGCCCCAGCCTGGCGGCCGATATTCAGCAAGCCTTT CGTGGATCGATAGACAATCATTTGAACGGCGAAGAAAGTCCGGTCATGAACGAGACCTTGAGCGTCATTGACGAG CACATCACGGATATGAACACCCCACGTCACAGCGTGTCGACCCAGGAACCCAGGACGATCAACGATTCCGGCAGC GAGTACAGCAGCCATATCGGCCACAGGGCTTCTTACATCAATGGAAATGAGACCGACGACGAGGAGCAGAGTCTT CCAACCGAGCAAGAGGTGCGGAAATGGAGTCCAACACAGACCTCAAGATGCTTGCGCAGCCTTGGCATTGATCAA AAACACTGTGACATCTTTGAAGAACAAGAGATCACCGGTGACGTGCTTCTTGATATGGATCAAGATTTTATTTTC ATGAAGGAGTTCGATTTTGGAGTCATGGGCAGGCGGCTCAAGACCTGGCACAAGGTCAAGGCCTTCCAAGAAGAG ACCAAGGGCTTCAGTCAGCAGCAAGCCCCAAGAGGCTCTATCTCCTCCAACTTCTCACCTTCCGATGAACGTGCA TTGTCTCGCGCTGGACACACCGGACCACTTCTTCCTCGGATTCCTACCTTGTCAGAAAAGACCGGCGCTGGTTAT CCACGAGGCTCTGTGCCGGTGCAGCACCCCCGACTGGCCAGCAACAGCAGCTCCCCCATGACACCGCATACCCCT CCGTACAGCCATGAATCAACGAGAAGGATTTCTGCGGCATCGCTCCGTGATCTCAACCAAGCGCGTCGTCATTCT TCCATTGACGCCACCCAACGAGGCATGCCTGATTCGGGTTTTGTTGGTCACCAGCAAAAGAAACCCTCATTCGAC CGGTCCTGGACTCTGAATTCCGGCCCCCAAGCCATGCCCGCTCGCCCAGGAACCTCCGCGGGCACTAGTCCGGGT GGCTTCCGGAATGGACCGCTGACCGCTGAGTCAGATTCTTACAACTCCTATGTCACCACCCCGGATCAGATTGAG GACCTAGATCGGGGTTATTTCTCGGGAACCGAGGTTGATTCGCGCCGGGCCCGCCGCGTTCTACAGAAACGGGGG TCGGCCGGTGTCGATGTAAACAATCAGTCACGAAAGTCAAGCTACGCAGATGATTCATACCAAGTGATATCCCCA GCGAAGCGCCACTCTCGCATTGGCAGTGTGGACTCGATACGTGACGCAGCGAATCGTGTCTCCCCCGCGGCCAAG GCCTATCACGGCACGCCACCGAAGAGTCGGCTGCGAAGCTTGAGCACGCGCGTCTTAACGGATAAAAGTGGAACC AGCTCTCAGTCGTCAACCACCGATAGCAAAACTAGTAACGGTGGTGGATTCTTCGCCAATTTCTCTCGTGTCGGT GGCAAAGGTGATTCGGAAATTCCTCGCGCTTCGCCGTTGCAATTCCAGCCACTGAAAAATGCCGGGCCCAAGTTT CGCCGAGCCATGGGCCTTCGAGCCATATCCGACGTTGCTGGAAAGAAGCTTGACACATCTGCGCTGCCTGATTCG CCGCTGGAGTCCGATCCTACCTCTGCTCGCACTGGATCCACAACTCCATCGGCGACGTCCAAGAGCTCGGAACGG CATAGTACAGATGGGTCTGGTAAGGCCACCACTGACGGACAGGGATTCGTAGCCCGTCCTCGAACGGCCAAGTCT AAGAAAGAGACTAGTGCCTATACTCGGGGTCTTGAGAAGAAGACACCGCAGGAGCAAATGGATGGTTGTGACTAC AGTGGATGGATGAAGAAGAGATCTTCCAACTTGATGACCACCTGGAAGCCCCGTCTGTTCGTCCTGCGCGGTCGT CGTCTGTCCTATTACTATTCCGAGGACGACACCGAGGAAAGAGGCTTGATCGATATCACCGCTCACCGTGTCCTA CGAGCAGATCAAGATCCGATCATTGCTCTACACGCAACCATCACCGGCTCAACCGCATTACCTGCCAATGCCAAC AACACCGTGGATAGCCCTAGCGGGACGAAACTCACCACTCCCTCGGTCATCCAATCGCTGACCACTAAGGACGGC AGTGGGCCGTTCTTCTTCAAGCTGGTGCCCCCAAAGTCAGGCAACTCGCGCACTGTGCAATTCACAAAACCAGCC ACCCACTTTTTCCAGGTTGACAATGTCCAGCAGGGTCGTCTGTGGATGGGAGCGTTGATGAAAGCGACCATCGAG CGTGACCTAGGACAGGCAGTGGAAACCACCAACAAGCAAAAGACTATTAGTCTAAAACAGGCCCGGCTGCTGCAG CAGCGGCCGGCAGATCTTGTTCCTGCTTCGGGTAGCACCAAGACCGCGCAGACCATCGATGAGGAAGAGGAAGAA GCGGGTCTGCAAATTGAGGGTTTGAACCTCAGTCAGTCTGATGTTAACTCTCTCGAGGACACGAACGGCAGTATT GATATTAACAACACAGATGAAGGCCTCGAACGACCTATCTCCAACCCCCTTGGGGATTTGGATAATGGCCAGTCG TCCTTGCTTCCGGATCCTCTAGCCAAGACGGAATCTAAGTGA
Transcript	>Pro_DTO377G3_2|g5036.t1 ATGTTTGCTATAGCTATCCTATACTCGATTCCTCTGGATCTGAATCTCAATTGTGCCACCTCTCAGCTCCTCTCC CTCAACCACGGGAAAGTCTCCCAAGTCCAGACTTTCTTACAATCGCACACGTCACTCTCGCCTTTCTCTTCGAAT TTGCGTCTTAGAAATCCAATCTATCTCTACAAGGTCGAGATCCTTCCCTTTGGACTTCTCACATTCTCTCCCCTT TCTCTTACCCTTCCGCCAAATCACATTACTCCCGAGTCTCCCCCAGATACACGGAATATTAAGATGGTTACCATG GGCCCACCGAAGGGTGTTCGTCCAGGCGACATTCTGGAGGTTCTTCATGAATTTGGCGGGCGCGGAGAAGACGAA CTGGTCATGTTACCCCGCGACAAGATTAAACTGATCGAGTTGGATGAGGAATTTGGAGATGCCTGGTACTACGGA CAGAACCTGAGGACGGGACAAACTGGTCTCTTCCCTGCAAACTTTACCAAAGTGGGCTCCCCAAGAAAGACCCTC GCCGAGTCGCCAGTTCTGGTAGAATCGCCGATCCAATTGGAATCCCTCGCGCGCCCAGATTCATCATTCGCATCG GCTGAGAGTGGACAGAGCACCCCTCAAGCATCGCGCCACGTTAGCTCCGACGATATGCAGTCACCGCAAATCAGT TCTCCCACACAGCATCGATCCGCCTCGTCTCCGCTGCCTCGCCCCAGCCTGGCGGCCGATATTCAGCAAGCCTTT CGTGGATCGATAGACAATCATTTGAACGGCGAAGAAAGTCCGGTCATGAACGAGACCTTGAGCGTCATTGACGAG CACATCACGGATATGAACACCCCACGTCACAGCGTGTCGACCCAGGAACCCAGGACGATCAACGATTCCGGCAGC GAGTACAGCAGCCATATCGGCCACAGGGCTTCTTACATCAATGGAAATGAGACCGACGACGAGGAGCAGAGTCTT CCAACCGAGCAAGAGGTGCGGAAATGGAGTCCAACACAGACCTCAAGATGCTTGCGCAGCCTTGGCATTGATCAA AAACACTGTGACATCTTTGAAGAACAAGAGATCACCGGTGACGTGCTTCTTGATATGGATCAAGATTTTATTTTC ATGAAGGAGTTCGATTTTGGAGTCATGGGCAGGCGGCTCAAGACCTGGCACAAGGTCAAGGCCTTCCAAGAAGAG ACCAAGGGCTTCAGTCAGCAGCAAGCCCCAAGAGGCTCTATCTCCTCCAACTTCTCACCTTCCGATGAACGTGCA TTGTCTCGCGCTGGACACACCGGACCACTTCTTCCTCGGATTCCTACCTTGTCAGAAAAGACCGGCGCTGGTTAT CCACGAGGCTCTGTGCCGGTGCAGCACCCCCGACTGGCCAGCAACAGCAGCTCCCCCATGACACCGCATACCCCT CCGTACAGCCATGAATCAACGAGAAGGATTTCTGCGGCATCGCTCCGTGATCTCAACCAAGCGCGTCGTCATTCT TCCATTGACGCCACCCAACGAGGCATGCCTGATTCGGGTTTTGTTGGTCACCAGCAAAAGAAACCCTCATTCGAC CGGTCCTGGACTCTGAATTCCGGCCCCCAAGCCATGCCCGCTCGCCCAGGAACCTCCGCGGGCACTAGTCCGGGT GGCTTCCGGAATGGACCGCTGACCGCTGAGTCAGATTCTTACAACTCCTATGTCACCACCCCGGATCAGATTGAG GACCTAGATCGGGGTTATTTCTCGGGAACCGAGGTTGATTCGCGCCGGGCCCGCCGCGTTCTACAGAAACGGGGG TCGGCCGGTGTCGATGTAAACAATCAGTCACGAAAGTCAAGCTACGCAGATGATTCATACCAAGTGATATCCCCA GCGAAGCGCCACTCTCGCATTGGCAGTGTGGACTCGATACGTGACGCAGCGAATCGTGTCTCCCCCGCGGCCAAG GCCTATCACGGCACGCCACCGAAGAGTCGGCTGCGAAGCTTGAGCACGCGCGTCTTAACGGATAAAAGTGGAACC AGCTCTCAGTCGTCAACCACCGATAGCAAAACTAGTAACGGTGGTGGATTCTTCGCCAATTTCTCTCGTGTCGGT GGCAAAGGTGATTCGGAAATTCCTCGCGCTTCGCCGTTGCAATTCCAGCCACTGAAAAATGCCGGGCCCAAGTTT CGCCGAGCCATGGGCCTTCGAGCCATATCCGACGTTGCTGGAAAGAAGCTTGACACATCTGCGCTGCCTGATTCG CCGCTGGAGTCCGATCCTACCTCTGCTCGCACTGGATCCACAACTCCATCGGCGACGTCCAAGAGCTCGGAACGG CATAGTACAGATGGGTCTGGTAAGGCCACCACTGACGGACAGGGATTCGTAGCCCGTCCTCGAACGGCCAAGTCT AAGAAAGAGACTAGTGCCTATACTCGGGGTCTTGAGAAGAAGACACCGCAGGAGCAAATGGATGGTTGTGACTAC AGTGGATGGATGAAGAAGAGATCTTCCAACTTGATGACCACCTGGAAGCCCCGTCTGTTCGTCCTGCGCGGTCGT CGTCTGTCCTATTACTATTCCGAGGACGACACCGAGGAAAGAGGCTTGATCGATATCACCGCTCACCGTGTCCTA CGAGCAGATCAAGATCCGATCATTGCTCTACACGCAACCATCACCGGCTCAACCGCATTACCTGCCAATGCCAAC AACACCGTGGATAGCCCTAGCGGGACGAAACTCACCACTCCCTCGGTCATCCAATCGCTGACCACTAAGGACGGC AGTGGGCCGTTCTTCTTCAAGCTGGTGCCCCCAAAGTCAGGCAACTCGCGCACTGTGCAATTCACAAAACCAGCC ACCCACTTTTTCCAGGTTGACAATGTCCAGCAGGGTCGTCTGTGGATGGGAGCGTTGATGAAAGCGACCATCGAG CGTGACCTAGGACAGGCAGTGGAAACCACCAACAAGCAAAAGACTATTAGTCTAAAACAGGCCCGGCTGCTGCAG CAGCGGCCGGCAGATCTTGTTCCTGCTTCGGGTAGCACCAAGACCGCGCAGACCATCGATGAGGAAGAGGAAGAA GCGGGTCTGCAAATTGAGGGTTTGAACCTCAGTCAGTCTGATGTTAACTCTCTCGAGGACACGAACGGCAGTATT GATATTAACAACACAGATGAAGGCCTCGAACGACCTATCTCCAACCCCCTTGGGGATTTGGATAATGGCCAGTCG TCCTTGCTTCCGGATCCTCTAGCCAAGACGGAATCTAAGTGA
Gene	>Pro_DTO377G3_2|g5036.t1 ATGTTTGCTATAGCTATCCTATACTCGATTCCTCTGGATCTGAATCTCAAGTGAATCTAATCCAATCTAATCCAT TCTAATCCTCTAATATAGATCGGGTGGACTTGGGCAAGAATGACCGGGTTCATCTGCATACAAGGCACATGTACT TCTGAAGTACTGTACGAAAACGGACCTAATTGCCCAGGTATGTTGCTAATTACTATTCAAGCTAAGCGCTAGGTA GTTGGTACTTATAGTGATTGTAATCGCAGTCCCTATATTATATGTAATCGCAGTTGTGCCACCTCTCAGCTCCTC TCCCTCAACCACGGGAAAGTCTCCCAAGTCCAGACTTTCTTACAATCGCACACGTCACTCTCGCCTTTCTCTTCG AATTTGCGTCTTAGGTTTGATATTGATTCAAATCCGAGTTCTGTCAATAATTTACCAATATTCTTGGTCGCGTTG AAAAAAGAAAAAAAAAAAGAAATCCAATCTATCTCTACAAGGTCGAGATCCTTCGTTCGTGCTCCCGAGCCCCGC GAGTTGTTTAACCTAATCCTTCTAATCTCCCGAATCTCTAGCCTTTGGACTTCTCACATTCTCTCCCCTTTCTCT TACCCTTCCGCCAAATCACATTACTCCCGAGTCTCCCCCAGTGGGATACGCAATTGCAATCTGCAATTTGCAAAT CTATCCCCAAGGGTGCCATGTTTTGTGTTGGCTCTTGACTAGGATACACGGAATATTAAGATGGTTACCATGGGC CCACCGAAGGGTGTTCGTCCAGGCGACATTCTGGAGGTTCTTCGTAAGTGACGTCGTGTGCGACACCTCGATTTC TGTGACTCCGCGTTTTTCAGGATGCGCCCGGCTTCTAACACTCCAAACTAGATGAATTTGGCGGGCGCGGAGAAG ACGAACTGGTCATGTTACCCCGCGACAAGATTAAACTGATCGAGTTGGATGAGGAATTTGGAGATGCCTGGTACT ACGGACAGAACCTGAGGACGGGACAAACTGGTCTCTTCCCTGCAAGTATGCGCCCCTTCCCCAGGACCCCCCCCC CTCTCACCACCCCCGACTATGATCCCAACTAATATTTGTTGCGCGACAGACTTTACCAAAGTGGGCTCCCCAAGA AAGACCCTCGCCGAGTCGCCAGTTCTGGTAGAATCGCCGATCCAATTGGAATCCCTCGCGCGCCCAGATTCATCA TTCGCATCGGCTGAGAGTGGACAGAGCACCCCTCAAGCATCGCGCCACGTTAGCTCCGACGATATGCAGTCACCG CAAATCAGTTCTCCCACACAGCATCGATCCGCCTCGTCTCCGCTGCCTCGCCCCAGCCTGGCGGCCGATATTCAG CAAGCCTTTCGTGGATCGATAGACAATCATTTGAACGGCGAAGAAAGTCCGGTCATGAACGAGACCTTGAGCGTC ATTGACGAGCACATCACGGATATGAACACCCCACGTCACAGCGTGTCGACCCAGGAACCCAGGACGATCAACGAT TCCGGCAGCGAGTACAGCAGCCATATCGGCCACAGGGCTTCTTACATCAATGGAAATGAGACCGACGACGAGGAG CAGAGTCTTCCAACCGAGCAAGAGGTGCGGAAATGGAGTCCAACACAGACCTCAAGATGCTTGCGCAGCCTTGGC ATTGATCAAAAACACTGTGACATCTTTGAAGAACAAGAGATCACCGGTGACGTGCTTCTTGATATGGATCAAGAT TTTATTTTCATGAAGGAGTTCGATTTTGGAGTCATGGGCAGGCGGCTCAAGACCTGGCACAAGGTCAAGGCCTTC CAAGAAGAGACCAAGGGCTTCAGTCAGCAGCAAGCCCCAAGAGGCTCTATCTCCTCCAACTTCTCACCTTCCGAT GAACGTGCATTGTCTCGCGCTGGACACACCGGACCACTTCTTCCTCGGATTCCTACCTTGTCAGAAAAGACCGGC GCTGGTTATCCACGAGGCTCTGTGCCGGTGCAGCACCCCCGACTGGCCAGCAACAGCAGCTCCCCCATGACACCG CATACCCCTCCGTACAGCCATGAATCAACGAGAAGGATTTCTGCGGCATCGCTCCGTGATCTCAACCAAGCGCGT CGTCATTCTTCCATTGACGCCACCCAACGAGGCATGCCTGATTCGGGTTTTGTTGGTCACCAGCAAAAGAAACCC TCATTCGACCGGTCCTGGACTCTGAATTCCGGCCCCCAAGCCATGCCCGCTCGCCCAGGAACCTCCGCGGGCACT AGTCCGGGTGGCTTCCGGAATGGACCGCTGACCGCTGAGTCAGATTCTTACAACTCCTATGTCACCACCCCGGAT CAGATTGAGGACCTAGATCGGGGTTATTTCTCGGGAACCGAGGTTGATTCGCGCCGGGCCCGCCGCGTTCTACAG AAACGGGGGTCGGCCGGTGTCGATGTAAACAATCAGTCACGAAAGTCAAGCTACGCAGATGATTCATACCAAGTG ATATCCCCAGCGAAGCGCCACTCTCGCATTGGCAGTGTGGACTCGATACGTGACGCAGCGAATCGTGTCTCCCCC GCGGCCAAGGCCTATCACGGCACGCCACCGAAGAGTCGGCTGCGAAGCTTGAGCACGCGCGTCTTAACGGATAAA AGTGGAACCAGCTCTCAGTCGTCAACCACCGATAGCAAAACTAGTAACGGTGGTGGATTCTTCGCCAATTTCTCT CGTGTCGGTGGCAAAGGTGATTCGGAAATTCCTCGCGCTTCGCCGTTGCAATTCCAGCCACTGAAAAATGCCGGG CCCAAGTTTCGCCGAGCCATGGGCCTTCGAGCCATATCCGACGTTGCTGGAAAGAAGCTTGACACATCTGCGCTG CCTGATTCGCCGCTGGAGTCCGATCCTACCTCTGCTCGCACTGGATCCACAACTCCATCGGCGACGTCCAAGAGC TCGGAACGGCATAGTACAGATGGGTCTGGTAAGGCCACCACTGACGGACAGGGATTCGTAGCCCGTCCTCGAACG GCCAAGTCTAAGAAAGAGACTAGTGCCTATACTCGGGGTCTTGAGAAGAAGACACCGCAGGAGCAAATGGATGGT TGTGACTACAGTGGATGGATGAAGAAGAGATCTTCCAACTTGATGACCACCTGGAAGCCCCGTCTGTTCGTCCTG CGCGGTCGTCGTCTGTCCTATTACTATTCCGAGGACGACACCGAGGAAAGAGGCTTGATCGATATCACCGCTCAC CGTGTCCTACGAGCAGATCAAGATCCGATCATTGCTCTACACGCAACCATCACCGGCTCAACCGCATTACCTGCC AATGCCAACAACACCGTGGATAGCCCTAGCGGGACGAAACTCACCACTCCCTCGGTCATCCAATCGCTGACCACT AAGGACGGCAGTGGGCCGTTCTTCTTCAAGCTGGTGCCCCCAAAGTCAGGCAACTCGCGCACTGTGCAATTCACA AAACCAGCCACCCACTTTTTCCAGGTTGACAATGTCCAGCAGGGTCGTCTGTGGATGGGAGCGTTGATGAAAGCG ACCATCGAGCGTGACCTAGGACAGGCAGTGGAAACCACCAACAAGCAAAAGACTATTAGTCTAAAACAGGCCCGG CTGCTGCAGCAGCGGCCGGCAGATCTTGTTCCTGCTTCGGGTAGCACCAAGACCGCGCAGACCATCGATGAGGAA GAGGAAGAAGCGGGTCTGCAAATTGAGGGTTTGAACCTCAGTCAGTCTGATGTTAACTCTCTCGAGGACACGAAC GGCAGTATTGATATTAACAACACAGATGAAGGCCTCGAACGACCTATCTCCAACCCCCTTGGGGATTTGGATAAT GGCCAGTCGTCCTTGCTTCCGGATCCTCTAGCCAAGACGGAATCTAAGTGA