Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g4913.t1
Gene name
Location	scaffold_11:41570..46040
Strand	-
Gene length (bp)	4470
Transcript length (bp)	4194
Coding sequence length (bp)	4194
Protein length (aa)	1398

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF16016	VASt	VAD1 Analog of StAR-related lipid transfer domain	1.4E-33	934	1078
PF16746	BAR_3	BAR domain of APPL family	6.7E-16	23	196
PF00169	PH	PH domain	4.9E-10	307	404

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 12	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g4913.t1 MSTQAQTPLPQVGKLVSVVPVGLKEAALDSPTFRATTLYFSDQIDFIEKWLDGYAKAATKLSYELTAMESVVNNF LSYSTHPLVVSEAVVDHDYTLLAMRRCGEGSKDLWSGLIATTRKLESLISEPIRDFIQEDLRQFKEIRRNLEQSQ KQYDYLQARYASQSKSKEASALREEAFQLHEAHKAYLKASMDYSVQGPQVRNALDRLLVKISCDQWREFRGFHNH NSGTFSKWSREMDRIKGWVNEMEGSEKSSKRELLATRKLIEEAAEFAARPSRELEDYNISTVPYLGSRPISALNV SKEMRPEKQGWLYLRTLSGKPTRTIWVKRWAFLKHGIFGCLVQGSRTGGVEESERIGVLLCSIRPASQEERRFCF QVKTKNNTILLQADNQKELMEWIGAFEAAKQKALENPASTDLSVSGKVTVQDPAFSISQPPAAEFAADPADSLTP HTNDESGAGDRSMTLPVPDRDGYTMRNSTDIGSSRRPTGFDSESSAREHAKEHTSRLIQKLDLHRKSNNAAPLSP SVPGPAGGIASLISASHNILPYSNAGPLNANVDGSRGRSLSNVDDPGSSLAPATLANPPAPTSMSKAAVVVSNER GIGIGVSDSTGGMPSGMMANVWGSSNWGFMNKLRRDQHQIDGVSDGPSTLGDGSTHTIAAQPDAAGTLVAPRQQS GPRHRQTVSLDGDDVKLTQVALGIGYEYPSYYPQQLRIQDAQFRLLFPDVKRVEALVLVFRATWSPNDQQEFPGR AYVTTRNIYFYSHHFGLVLTTGVSLESIKEVTAAPGRDCDFLFLHTIPPLGSDTPGRVTIKTFLEPLRLLQKRLN FLIQCSIAVEQLSLESLIKALIKMDTGSSARTSSADSWDDLSSGLAGIKHDGGKATDLGHAKDIRLPIYVDKDLE LDGGRTARGRDIAKFRLPTQPVEYVPQGDLVLVTEKILDISPKALFHILFGDKSAVWQLLLHERKALEIQQGPWA STDLRHLKRDFHYNIATTDILGRTHENAISDYQIIDVLNDHLCYVITDKKTPWHLPFRRSFRLVTKVVITFQAKS KSKLAIYTKVEWLWSPYGLKNVIDKKASEDLEQDSLDLVDLVSDQVRRLGAHSRTKKAITIFGHVGRQNNVSQFS GAGSNLKLEPRKPRTQRAMHDLLFETFLSFLETSVSFIMVWAFDVVRWSWKTMSAHKIILTMLATSAILNGYYSS RDSWDWWHERHAGNFMARLGVQPNLVMSKSIYMRDIDDAVANSTIWPGAGNASDCFATFHEQTMRYADMPLSLSP SGPRDALTKSAIKRFQQTRERLGMYRHNLLVALRVVNSIEKEVVQTEWERWLREEVRRCRQVEVLLGGEATPGDD SQTGRTTKAERVFAEHADNVKQWHEEYCSSCRMEQEHVISNNPDLIP*
Coding	>Pro_DTO377G3_2|g4913.t1 ATGTCGACTCAAGCACAAACCCCGTTACCCCAAGTTGGGAAACTTGTGAGCGTTGTCCCGGTCGGTCTCAAAGAA GCCGCTCTCGACTCGCCCACCTTTCGTGCCACCACCCTTTATTTCTCTGATCAGATCGATTTCATAGAGAAATGG CTCGACGGATATGCCAAAGCTGCAACCAAGCTCTCCTACGAGCTGACCGCTATGGAGAGTGTAGTGAACAACTTT CTTTCCTACTCGACACATCCCCTCGTGGTCTCGGAAGCGGTCGTTGACCATGATTACACACTTTTGGCTATGAGG AGATGTGGTGAGGGGTCTAAAGATCTTTGGAGTGGACTCATCGCAACAACCAGAAAGTTGGAGTCGTTGATTTCC GAACCTATTCGAGATTTCATTCAAGAGGATCTGCGGCAGTTCAAGGAAATTCGCCGCAACCTCGAGCAATCACAG AAACAGTACGATTACCTCCAAGCTCGATATGCCTCTCAGTCGAAGTCCAAGGAGGCCTCGGCCCTGAGAGAAGAA GCATTTCAGCTGCACGAAGCCCACAAGGCCTACCTGAAAGCATCAATGGACTATTCAGTACAGGGTCCTCAGGTA CGAAATGCACTGGACCGACTTCTGGTCAAAATCTCCTGCGATCAATGGAGGGAATTCCGGGGATTTCACAATCAC AACAGCGGGACCTTCTCGAAATGGTCGCGTGAGATGGATCGTATTAAGGGTTGGGTTAATGAGATGGAAGGCAGT GAGAAATCATCCAAACGAGAGCTGCTAGCCACCCGGAAGCTCATTGAGGAAGCCGCGGAGTTTGCGGCTCGACCG TCTCGTGAACTGGAGGACTACAATATTTCGACCGTTCCGTACCTTGGCTCTCGTCCTATTTCGGCACTTAATGTG AGCAAAGAGATGAGACCAGAGAAGCAAGGATGGCTGTATTTGCGCACATTGTCAGGAAAGCCTACTCGCACAATT TGGGTCAAACGGTGGGCTTTTCTCAAGCACGGCATATTTGGATGTCTTGTACAGGGCTCTCGTACTGGCGGTGTT GAAGAGAGTGAAAGAATTGGTGTATTGCTTTGCAGTATCCGTCCTGCATCACAGGAGGAACGCCGGTTCTGCTTC CAAGTGAAGACCAAGAACAACACCATTCTACTTCAGGCAGATAACCAGAAGGAGCTGATGGAATGGATTGGTGCC TTCGAGGCGGCCAAACAAAAAGCACTGGAGAACCCCGCAAGCACTGATCTCTCGGTTTCTGGAAAAGTCACAGTT CAAGACCCTGCATTTTCAATTTCTCAACCCCCGGCTGCGGAGTTCGCTGCGGATCCTGCTGACTCTCTTACCCCT CATACGAACGATGAGTCCGGAGCGGGGGATCGCAGTATGACGCTTCCTGTTCCAGACCGTGATGGATATACCATG AGAAATAGTACCGATATTGGAAGCAGCAGAAGACCAACAGGCTTCGATAGTGAGAGCTCTGCAAGAGAACATGCA AAAGAGCATACCTCTAGACTCATCCAAAAGTTGGATCTTCACCGCAAATCGAACAATGCGGCTCCACTATCTCCT TCCGTCCCTGGCCCTGCAGGTGGAATAGCCAGTCTCATCTCTGCCAGCCACAATATTCTCCCTTACAGCAACGCC GGTCCACTCAACGCCAACGTCGATGGCAGTCGAGGTCGCAGTTTAAGCAACGTGGATGATCCTGGCTCAAGTCTT GCACCTGCCACGCTCGCCAATCCCCCGGCACCCACAAGCATGAGCAAGGCGGCAGTGGTTGTGAGCAATGAAAGA GGCATTGGAATAGGCGTCTCTGATAGTACGGGTGGTATGCCTAGTGGTATGATGGCGAACGTGTGGGGTAGCTCT AACTGGGGTTTCATGAACAAGCTTCGACGGGACCAACACCAGATTGATGGAGTATCTGATGGGCCGTCTACATTG GGTGATGGCTCAACACACACGATTGCCGCACAACCCGATGCAGCGGGTACTTTAGTGGCACCCCGACAGCAATCA GGTCCACGCCACAGGCAGACAGTAAGCCTTGATGGGGACGATGTTAAGCTCACGCAAGTTGCACTGGGTATCGGG TATGAATATCCCAGCTACTACCCTCAACAATTGAGGATTCAAGATGCTCAGTTCAGATTGCTTTTCCCAGACGTC AAGAGAGTGGAAGCATTGGTCTTGGTGTTCAGAGCCACCTGGAGCCCTAACGACCAGCAAGAATTCCCCGGACGA GCTTATGTCACAACAAGGAACATTTACTTTTATAGCCATCATTTCGGACTGGTTTTGACTACCGGTGTGTCTTTG GAGAGCATTAAGGAGGTAACTGCAGCTCCTGGGCGAGACTGTGACTTCCTTTTCCTTCATACTATTCCACCCCTC GGCAGTGATACTCCTGGCCGGGTTACGATCAAAACTTTCCTTGAACCTCTCCGACTTCTTCAAAAACGACTCAAC TTCTTGATCCAATGCTCCATTGCCGTCGAGCAATTGAGTTTAGAATCCTTGATCAAAGCTTTGATCAAGATGGAC ACTGGGTCTTCAGCCCGAACTTCCAGTGCAGATAGCTGGGATGATCTTTCATCCGGACTCGCAGGCATCAAACAT GACGGGGGCAAAGCTACAGACCTGGGCCATGCGAAGGACATTCGACTGCCTATTTACGTTGACAAAGATCTTGAG CTGGATGGAGGCAGGACTGCCCGTGGTCGGGATATTGCTAAATTCAGACTTCCAACACAACCCGTGGAGTATGTT CCACAAGGCGATCTTGTCTTGGTGACCGAAAAAATTCTCGATATAAGCCCTAAAGCTTTGTTCCATATATTATTT GGCGACAAAAGCGCCGTGTGGCAGCTTCTTTTACACGAGAGGAAAGCTCTAGAGATCCAACAAGGCCCATGGGCT AGTACGGACTTGCGGCATCTGAAGCGTGACTTCCACTACAATATCGCCACGACAGATATCCTTGGTCGTACTCAC GAAAATGCGATATCGGATTATCAGATCATTGATGTTCTCAACGACCATCTGTGCTACGTGATCACAGATAAAAAG ACTCCGTGGCATCTCCCCTTCCGCCGTTCGTTCCGGTTGGTTACCAAGGTTGTCATTACATTCCAGGCCAAGTCG AAGAGCAAGCTTGCTATTTATACGAAAGTCGAGTGGCTGTGGTCTCCCTACGGCCTCAAAAACGTGATCGACAAA AAAGCAAGTGAAGATCTAGAACAAGACTCCTTGGATCTTGTCGACCTAGTCAGTGACCAAGTACGTCGATTGGGT GCACACAGTCGCACCAAAAAAGCCATCACGATCTTCGGCCATGTTGGACGCCAAAACAACGTCTCCCAATTTAGT GGCGCTGGTTCCAACCTGAAGCTGGAACCTCGCAAGCCCCGAACACAGCGTGCTATGCACGACCTTCTTTTCGAG ACCTTCTTGTCATTCCTCGAAACGAGTGTTTCCTTCATAATGGTTTGGGCGTTTGACGTAGTTCGCTGGTCTTGG AAGACCATGAGTGCTCACAAGATCATCCTGACCATGTTGGCTACAAGTGCCATTTTGAATGGATACTATTCTTCG CGGGATAGTTGGGACTGGTGGCACGAGAGACATGCAGGCAACTTCATGGCACGGCTGGGTGTACAGCCAAACCTC GTTATGAGCAAATCTATCTACATGCGGGATATTGATGACGCGGTTGCAAACTCCACAATTTGGCCCGGCGCCGGC AATGCCAGTGATTGCTTTGCTACCTTCCACGAGCAGACCATGCGGTATGCCGATATGCCTCTGTCGCTCAGTCCA TCCGGACCCCGGGATGCATTGACCAAGAGCGCCATCAAACGCTTCCAGCAAACTCGTGAGCGTCTTGGCATGTAT CGACACAACCTTCTTGTCGCATTGCGTGTCGTGAACAGTATTGAGAAAGAGGTCGTCCAGACGGAATGGGAGCGT TGGCTGCGCGAGGAGGTCCGGCGCTGTCGCCAGGTCGAGGTTCTCCTTGGCGGAGAGGCCACTCCGGGCGACGAC TCGCAGACGGGCCGAACGACCAAAGCTGAGCGTGTCTTTGCCGAGCATGCTGACAACGTCAAGCAGTGGCATGAG GAGTACTGCTCGAGTTGTCGAATGGAGCAAGAACATGTCATATCCAATAATCCTGACCTAATTCCTTGA
Transcript	>Pro_DTO377G3_2|g4913.t1 ATGTCGACTCAAGCACAAACCCCGTTACCCCAAGTTGGGAAACTTGTGAGCGTTGTCCCGGTCGGTCTCAAAGAA GCCGCTCTCGACTCGCCCACCTTTCGTGCCACCACCCTTTATTTCTCTGATCAGATCGATTTCATAGAGAAATGG CTCGACGGATATGCCAAAGCTGCAACCAAGCTCTCCTACGAGCTGACCGCTATGGAGAGTGTAGTGAACAACTTT CTTTCCTACTCGACACATCCCCTCGTGGTCTCGGAAGCGGTCGTTGACCATGATTACACACTTTTGGCTATGAGG AGATGTGGTGAGGGGTCTAAAGATCTTTGGAGTGGACTCATCGCAACAACCAGAAAGTTGGAGTCGTTGATTTCC GAACCTATTCGAGATTTCATTCAAGAGGATCTGCGGCAGTTCAAGGAAATTCGCCGCAACCTCGAGCAATCACAG AAACAGTACGATTACCTCCAAGCTCGATATGCCTCTCAGTCGAAGTCCAAGGAGGCCTCGGCCCTGAGAGAAGAA GCATTTCAGCTGCACGAAGCCCACAAGGCCTACCTGAAAGCATCAATGGACTATTCAGTACAGGGTCCTCAGGTA CGAAATGCACTGGACCGACTTCTGGTCAAAATCTCCTGCGATCAATGGAGGGAATTCCGGGGATTTCACAATCAC AACAGCGGGACCTTCTCGAAATGGTCGCGTGAGATGGATCGTATTAAGGGTTGGGTTAATGAGATGGAAGGCAGT GAGAAATCATCCAAACGAGAGCTGCTAGCCACCCGGAAGCTCATTGAGGAAGCCGCGGAGTTTGCGGCTCGACCG TCTCGTGAACTGGAGGACTACAATATTTCGACCGTTCCGTACCTTGGCTCTCGTCCTATTTCGGCACTTAATGTG AGCAAAGAGATGAGACCAGAGAAGCAAGGATGGCTGTATTTGCGCACATTGTCAGGAAAGCCTACTCGCACAATT TGGGTCAAACGGTGGGCTTTTCTCAAGCACGGCATATTTGGATGTCTTGTACAGGGCTCTCGTACTGGCGGTGTT GAAGAGAGTGAAAGAATTGGTGTATTGCTTTGCAGTATCCGTCCTGCATCACAGGAGGAACGCCGGTTCTGCTTC CAAGTGAAGACCAAGAACAACACCATTCTACTTCAGGCAGATAACCAGAAGGAGCTGATGGAATGGATTGGTGCC TTCGAGGCGGCCAAACAAAAAGCACTGGAGAACCCCGCAAGCACTGATCTCTCGGTTTCTGGAAAAGTCACAGTT CAAGACCCTGCATTTTCAATTTCTCAACCCCCGGCTGCGGAGTTCGCTGCGGATCCTGCTGACTCTCTTACCCCT CATACGAACGATGAGTCCGGAGCGGGGGATCGCAGTATGACGCTTCCTGTTCCAGACCGTGATGGATATACCATG AGAAATAGTACCGATATTGGAAGCAGCAGAAGACCAACAGGCTTCGATAGTGAGAGCTCTGCAAGAGAACATGCA AAAGAGCATACCTCTAGACTCATCCAAAAGTTGGATCTTCACCGCAAATCGAACAATGCGGCTCCACTATCTCCT TCCGTCCCTGGCCCTGCAGGTGGAATAGCCAGTCTCATCTCTGCCAGCCACAATATTCTCCCTTACAGCAACGCC GGTCCACTCAACGCCAACGTCGATGGCAGTCGAGGTCGCAGTTTAAGCAACGTGGATGATCCTGGCTCAAGTCTT GCACCTGCCACGCTCGCCAATCCCCCGGCACCCACAAGCATGAGCAAGGCGGCAGTGGTTGTGAGCAATGAAAGA GGCATTGGAATAGGCGTCTCTGATAGTACGGGTGGTATGCCTAGTGGTATGATGGCGAACGTGTGGGGTAGCTCT AACTGGGGTTTCATGAACAAGCTTCGACGGGACCAACACCAGATTGATGGAGTATCTGATGGGCCGTCTACATTG GGTGATGGCTCAACACACACGATTGCCGCACAACCCGATGCAGCGGGTACTTTAGTGGCACCCCGACAGCAATCA GGTCCACGCCACAGGCAGACAGTAAGCCTTGATGGGGACGATGTTAAGCTCACGCAAGTTGCACTGGGTATCGGG TATGAATATCCCAGCTACTACCCTCAACAATTGAGGATTCAAGATGCTCAGTTCAGATTGCTTTTCCCAGACGTC AAGAGAGTGGAAGCATTGGTCTTGGTGTTCAGAGCCACCTGGAGCCCTAACGACCAGCAAGAATTCCCCGGACGA GCTTATGTCACAACAAGGAACATTTACTTTTATAGCCATCATTTCGGACTGGTTTTGACTACCGGTGTGTCTTTG GAGAGCATTAAGGAGGTAACTGCAGCTCCTGGGCGAGACTGTGACTTCCTTTTCCTTCATACTATTCCACCCCTC GGCAGTGATACTCCTGGCCGGGTTACGATCAAAACTTTCCTTGAACCTCTCCGACTTCTTCAAAAACGACTCAAC TTCTTGATCCAATGCTCCATTGCCGTCGAGCAATTGAGTTTAGAATCCTTGATCAAAGCTTTGATCAAGATGGAC ACTGGGTCTTCAGCCCGAACTTCCAGTGCAGATAGCTGGGATGATCTTTCATCCGGACTCGCAGGCATCAAACAT GACGGGGGCAAAGCTACAGACCTGGGCCATGCGAAGGACATTCGACTGCCTATTTACGTTGACAAAGATCTTGAG CTGGATGGAGGCAGGACTGCCCGTGGTCGGGATATTGCTAAATTCAGACTTCCAACACAACCCGTGGAGTATGTT CCACAAGGCGATCTTGTCTTGGTGACCGAAAAAATTCTCGATATAAGCCCTAAAGCTTTGTTCCATATATTATTT GGCGACAAAAGCGCCGTGTGGCAGCTTCTTTTACACGAGAGGAAAGCTCTAGAGATCCAACAAGGCCCATGGGCT AGTACGGACTTGCGGCATCTGAAGCGTGACTTCCACTACAATATCGCCACGACAGATATCCTTGGTCGTACTCAC GAAAATGCGATATCGGATTATCAGATCATTGATGTTCTCAACGACCATCTGTGCTACGTGATCACAGATAAAAAG ACTCCGTGGCATCTCCCCTTCCGCCGTTCGTTCCGGTTGGTTACCAAGGTTGTCATTACATTCCAGGCCAAGTCG AAGAGCAAGCTTGCTATTTATACGAAAGTCGAGTGGCTGTGGTCTCCCTACGGCCTCAAAAACGTGATCGACAAA AAAGCAAGTGAAGATCTAGAACAAGACTCCTTGGATCTTGTCGACCTAGTCAGTGACCAAGTACGTCGATTGGGT GCACACAGTCGCACCAAAAAAGCCATCACGATCTTCGGCCATGTTGGACGCCAAAACAACGTCTCCCAATTTAGT GGCGCTGGTTCCAACCTGAAGCTGGAACCTCGCAAGCCCCGAACACAGCGTGCTATGCACGACCTTCTTTTCGAG ACCTTCTTGTCATTCCTCGAAACGAGTGTTTCCTTCATAATGGTTTGGGCGTTTGACGTAGTTCGCTGGTCTTGG AAGACCATGAGTGCTCACAAGATCATCCTGACCATGTTGGCTACAAGTGCCATTTTGAATGGATACTATTCTTCG CGGGATAGTTGGGACTGGTGGCACGAGAGACATGCAGGCAACTTCATGGCACGGCTGGGTGTACAGCCAAACCTC GTTATGAGCAAATCTATCTACATGCGGGATATTGATGACGCGGTTGCAAACTCCACAATTTGGCCCGGCGCCGGC AATGCCAGTGATTGCTTTGCTACCTTCCACGAGCAGACCATGCGGTATGCCGATATGCCTCTGTCGCTCAGTCCA TCCGGACCCCGGGATGCATTGACCAAGAGCGCCATCAAACGCTTCCAGCAAACTCGTGAGCGTCTTGGCATGTAT CGACACAACCTTCTTGTCGCATTGCGTGTCGTGAACAGTATTGAGAAAGAGGTCGTCCAGACGGAATGGGAGCGT TGGCTGCGCGAGGAGGTCCGGCGCTGTCGCCAGGTCGAGGTTCTCCTTGGCGGAGAGGCCACTCCGGGCGACGAC TCGCAGACGGGCCGAACGACCAAAGCTGAGCGTGTCTTTGCCGAGCATGCTGACAACGTCAAGCAGTGGCATGAG GAGTACTGCTCGAGTTGTCGAATGGAGCAAGAACATGTCATATCCAATAATCCTGACCTAATTCCTTGA
Gene	>Pro_DTO377G3_2|g4913.t1 ATGTCGACTCAAGCACAAACCCCGTTACCCCAAGTTGGGAAACTTGTGAGCGTTGTGTGAGTATCTCATATGCCT GATATTGGAATTCTCGTTCTTGTATACTAATGCATGCGCCCCTTTTCAGCCCGGTCGGTCTCAAAGAAGCCGCTC TCGACTCGCCCACCTTTCGTGCCACCACCCTTTATTTCTCTGATCAGATCGATTTCATAGAGAAATGGCTCGACG GATATGCCAAAGCTGCAACCAAGCTCTCCTACGAGCTGACCGCTATGGAGAGTGTAGTGAACAACTTTCTTTCCT ACTCGACACATCCCCTCGTGGTCTCGGAAGCGGTCGTTGACCATGATTACACACTTTTGGCTATGAGGAGATGTG GTGAGGGGTCTAAAGATCTTTGGAGTGGACTCATCGCAACAACCAGAAAGTTGGAGTCGTTGATTTCCGAACCTA TTCGAGATTTCATTCAAGAGGATCTGCGGCAGTTCAAGGTATTAAGAAGCCCCTCATCCAATCTGTTCTCGGATT ATCTGACACGTCCATAGGAAATTCGCCGCAACCTCGAGCAATCACAGAAACAGTACGATTACCTCCAAGCTCGAT ATGCCTCTCAGTCGAAGTCCAAGGAGGCCTCGGCCCTGAGAGAAGAAGCATTTCAGCTGCACGAAGCCCACAAGG CCTACCTGAAAGCATCAATGGACTATTCAGTACAGGGTCCTCAGGTACGAAATGCACTGGACCGACTTCTGGTCA AAATCTCCTGCGATCAATGGAGGGAATTCCGGGGATTTCACAATCACAACAGCGGGACCTTCTCGAAATGGTCGC GTGAGATGGATCGTATTAAGGGTTGGGTTAATGAGATGGAAGGCAGTGAGAAATCATCCAAACGAGAGCTGCTAG CCACCCGGAAGCTCATTGAGGAAGCCGCGGAGTTTGCGGCTCGACCGTCTCGTGAACTGGAGGACTACAATATTT CGACCGTTCCGTACCTTGGCTCTCGTCCTATTTCGGCACTTAATGTGAGCAAAGAGATGAGACCAGAGAAGCAAG GATGGCTGTATTTGCGCACATTGTCAGGAAAGCCTACTCGCACAATTTGGGTCAAACGGTGGGCTTTTCTCAAGC ACGGCATATTTGGATGTCTTGTACAGGGCTCTCGTACTGGCGGTGTTGAAGAGAGTGAAAGAATTGGTGTATTGC TTTGCAGTATCCGTCCTGCATCACAGGAGGAACGCCGGTTCTGCTTCCAAGTGAAGACCAAGAACAACACCATTC TACTTCAGGCAGATAACCAGAAGGAGCTGATGGAATGGATTGGTGCCTTCGAGGCGGCCAAACAAAAAGCACTGG AGAACCCCGCAAGCACTGATCTCTCGGTTTCTGGAAAAGTCACAGTTCAAGACCCTGCATTTTCAATTTCTCAAC CCCCGGCTGCGGAGTTCGCTGCGGATCCTGCTGACTCTCTTACCCCTCATACGAACGATGAGTCCGGAGCGGGGG ATCGCAGTATGACGCTTCCTGTTCCAGACCGTGATGGATATACCATGAGAAATAGTACCGATATTGGAAGCAGCA GAAGACCAACAGGCTTCGATAGTGAGAGCTCTGCAAGAGAACATGCAAAAGAGCATACCTCTAGACTCATCCAAA AGTTGGATCTTCACCGCAAATCGAACAATGCGGCTCCACTATCTCCTTCCGTCCCTGGCCCTGCAGGTGGAATAG CCAGTCTCATCTCTGCCAGCCACAATATTCTCCCTTACAGCAACGCCGGTCCACTCAACGCCAACGTCGATGGCA GTCGAGGTCGCAGTTTAAGCAACGTGGATGATCCTGGCTCAAGTCTTGCACCTGCCACGCTCGCCAATCCCCCGG CACCCACAAGCATGAGCAAGGCGGCAGTGGTTGTGAGCAATGAAAGAGGCATTGGAATAGGCGTCTCTGATAGTA CGGGTGGTATGCCTAGTGGTATGATGGCGAACGTGTGGGGTAGCTCTAACTGGGGTTTCATGAACAAGCTTCGAC GGGACCAACACCAGATTGATGGAGTATCTGATGGGCCGTCTACATTGGGTGATGGCTCAACACACACGATTGCCG CACAACCCGATGCAGCGGGTACTTTAGTGGCACCCCGACAGCAATCAGGTCCACGCCACAGGCAGACAGTAAGCC TTGATGGGGACGATGTTAAGCTCACGCAAGTTGCACTGGGTATCGGGTATGAATATCCCAGCTACTACCCTCAAC AATTGAGGATTCAAGATGCTCAGTTCAGATTGCTTTTCCCAGACGTCAAGAGAGTGGAAGCATTGGTCTTGGTGT TCAGAGCCACCTGGAGCCCTAACGACCAGCAAGAATTCCCCGGACGAGCTTATGTCACAACAAGGAACATTTACT TTTATAGCCATCATTTCGGACTGGTTTTGACTACCGGTGTGTCTTTGGAGAGCATTAAGGAGGTAACTGCAGCTC CTGGGCGAGACTGTGACTTCCTTTTCCTTCATACTATTCCACCCCTCGGCAGTGATACTCCTGGCCGGGTTACGA TCAAAACTTTCCTTGAACCTCTCCGACTTCTTCAAAAACGACTCAACTTCTTGATCCAATGCTCCATTGCCGTCG AGCAATTGAGTTTAGAATCCTTGATCAAAGCTTTGATCAAGATGGACACTGGGTCTTCAGCCCGAACTTCCAGTG CAGATAGCTGGGATGATCTTTCATCCGGACTCGCAGGCATCAAACATGACGGGGGCAAAGCTACAGACCTGGGCC ATGCGAAGGACATTCGACTGCCTATTTACGTTGACAAAGATCTTGAGCTGGATGGAGGCAGGACTGCCCGTGGTC GGGATATTGCTAAATTCAGACTTCCAACACAACCCGTGGAGTATGTTCCACAAGGCGATCTTGTCTTGGTGACCG AAAAAATTCTCGATATAAGCCCTAAAGCTTTGTTCCATATATTATTTGGCGACAAAAGCGCCGTGTGGCAGCTTC TTTTACACGAGAGGAAAGCTCTAGGTTCGTTTATTCTAAATCCTTAATCACTTATACATGGCTGACATTTCAAAG AGATCCAACAAGGCCCATGGGCTAGTACGGACTTGCGGCATCTGAAGCGTGACTTCCACTACAATATCGCCACGA CAGATATCCTTGGTAGGCTTGATTATTGATGATCTTGAGATCGAGCCATGACTGATTTTGTATAGGTCGTACTCA CGAAAATGCGATATCGGATTATCAGATCATTGATGTTCTCAACGACCATCTGTGCTACGTGATCACAGATAAAAA GACTCCGTGGCATCTCCCCTTCCGCCGTTCGTTCCGGTTGGTTACCAAGGTTGTCATTACATTCCAGGCCAAGTC GAAGAGCAAGCTTGCTATTTATACGAAAGTCGAGTGGCTGTGGTCTCCCTACGGCCTCAAAAGTGAGTTATCCCC TCCCATCCCTCCCATTCGAATATTCTAACATACCTAGACGTGATCGACAAAAAAGCAAGTGAAGATCTAGAACAA GACTCCTTGGATCTTGTCGACCTAGTCAGTGACCAAGTACGTCGATTGGGTGCACACAGTCGCACCAAAAAAGCC ATCACGATCTTCGGCCATGTTGGACGCCAAAACAACGTCTCCCAATTTAGTGGCGCTGGTTCCAACCTGAAGCTG GAACCTCGCAAGCCCCGAACACAGCGTGCTATGCACGACCTTCTTTTCGAGACCTTCTTGTCATTCCTCGAAACG AGTGTTTCCTTCATAATGGTTTGGGCGTTTGACGTAGTTCGCTGGTCTTGGAAGACCATGAGTGCTCACAAGATC ATCCTGACCATGTTGGCTACAAGTGCCATTTTGAATGGATACTATTCTTCGCGGGATAGTTGGGACTGGTGGCAC GAGAGACATGCAGGCAACTTCATGGCACGGCTGGGTGTACAGCCAAACCTCGTTATGAGCAAATCTATCTACATG CGGGATATTGATGACGCGGTTGCAAACTCCACAATTTGGCCCGGCGCCGGCAATGCCAGTGATTGCTTTGCTACC TTCCACGAGCAGACCATGCGGTATGCCGATATGCCTCTGTCGCTCAGTCCATCCGGACCCCGGGATGCATTGACC AAGAGCGCCATCAAACGCTTCCAGCAAACTCGTGAGCGTCTTGGCATGTATCGACACAACCTTCTTGTCGCATTG CGTGTCGTGAACAGTATTGAGAAAGAGGTCGTCCAGACGGAATGGGAGCGTTGGCTGCGCGAGGAGGTCCGGCGC TGTCGCCAGGTCGAGGTTCTCCTTGGCGGAGAGGCCACTCCGGGCGACGACTCGCAGACGGGCCGAACGACCAAA GCTGAGCGTGTCTTTGCCGAGCATGCTGACAACGTCAAGCAGTGGCATGAGGAGTACTGCTCGAGTTGTCGAATG GAGCAAGAACATGTCATATCCAATAATCCTGACCTAATTCCTTGA