Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g4563.t1
Gene name
Location	scaffold_09:567145..571374
Strand	-
Gene length (bp)	4229
Transcript length (bp)	3828
Coding sequence length (bp)	3828
Protein length (aa)	1276

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF12763	EF-hand_4	Cytoskeletal-regulatory complex EF hand	2.0E-11	137	224
PF12763	EF-hand_4	Cytoskeletal-regulatory complex EF hand	8.2E-14	290	379
PF00627	UBA	UBA/TS-N domain	9.8E-06	1239	1271

GO

GO Term	Description	Terminal node
GO:0005515	protein binding	Yes
GO:0005488	binding	No
GO:0003674	molecular_function	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 22	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g4563.t1 MADTAQRHPNLHLTPEEKRVFFQLFQAADTTNLGVITGEIAVPFFEKTHLSPDTLGLIWQIADKENRGLLTPSGF GIVLRLIGHAQAGRAPSDELALQSGPLPRFDGIVVDTTASVPESGTKSPPPGANGPIRVPPLQPDDANKFVSLFE KSDVKNGMISGEIAKQIFERARLPNEVLGRIWFLSDTKQRGALDATEFTIAMHLLTSYKSGALRGIPATLPPGLY DAAARRGPPARVSFGARPDVPPIPAIPQQFTGPQRTTSPMNQANRSPFVGSLSAQVTGGDWLITPQEKAQFDSIF ETVDTAKLGLITGDQAVSFFMKAQLPEETLAQIWDLADIDADGQLSREEFAVAMYLVRLQRSGKEPLPQVVPPAL IPPNMRRQVPAPMAAPTPPPAPAPVVRTAADDLFGLDSPAPPFAQPQMPQSTGGSNSAFQTPGSPSSRASPQTAS QTFKPFIPTSTFGQSLQPQITGASAATPRAVRSPPPPSDDLLGDNDPEESNKLTNETTELANLSNQIGSLAKEMH TVQEKRTFAEQSITQTSQQKRDFEARLAQARSMYEQEVTNFKALEERLKSSKAETQKLQQQYALLDGSRQDLQNQ YTQVSTALASDEQENSSLKEKIRQANAEVAQLKPALEKARSSARQQKGLVAINKKQLATVEGERDKLQGEIDSLA NETPQYSQESATPAGSVADVVSPAASTTSQNTNPFFRRTGSSSEQARSPDVSNDQQKAFDSLFGQPFAAFPAAGP PPTSFRSESPQVAVTSPITSAVTTPSVSPPPGSLPGAFPSGAFSEPPPASQSRQLTPNFLQFNDNQSVTSSTMVS PPASRFGGAETSGIATPSQAASSDYGPTSGPESSDYTRAPTSTFEGTPARSPFEEEGQDLSVRFPEPSKTVQQPQ SAATPVANESQVEDGKDLSFDELFGSKAHKRSESQQDNDFEEAFASMKPVPGAEQPNGAASARPSEFPPIQELHH DDDEDESSDDEGAFGFEDNFTPPAPNVQKETQQDSIDAAQLAAFPVPGTSNKPPSPGVLQSPPEYETAKEDNVHL PPQFNGLLPERGDPTVAPDAPHSVEHTTGAPVVSNETNRDSVSDAAIPPGGAKVGGPDFEAAFAGMNLAPAIEAD DDDDDEPQGQEAKNTTDFDFSFDSPSQKQQAVSGADAQSSSSQFFAFDNNIHASAAPPVGSPNGGEPKPAALHEW DTLFAPLDNAKPDIGEDANDAKSKQPGWALNNDTGDDLILQRLTGMGFTRDESLDALEKYDYNLDKAADHLTSRT *
Coding	>Pro_DTO377G3_2|g4563.t1 ATGGCTGATACCGCACAGCGACACCCGAATCTTCACCTCACTCCAGAGGAAAAGCGCGTATTCTTCCAGCTTTTC CAGGCTGCCGATACCACCAATCTCGGGGTCATTACCGGTGAAATCGCCGTTCCATTCTTTGAGAAGACTCACCTA TCCCCGGATACTCTCGGCCTGATTTGGCAAATTGCCGATAAAGAGAACAGGGGCCTCCTGACCCCATCTGGCTTC GGGATTGTTCTGCGGTTAATTGGACATGCCCAAGCTGGCCGTGCACCTTCGGACGAGTTGGCTCTGCAATCTGGC CCTCTGCCTCGTTTTGACGGAATTGTGGTCGACACAACGGCAAGCGTCCCGGAATCCGGAACCAAAAGCCCTCCA CCTGGAGCCAATGGACCTATTCGTGTTCCACCCCTTCAGCCTGATGATGCCAATAAATTCGTCTCGCTGTTCGAG AAGTCGGACGTCAAGAACGGGATGATCTCAGGCGAAATTGCAAAACAGATCTTCGAACGCGCTCGGCTCCCAAAT GAGGTTCTGGGTCGCATCTGGTTTTTGTCTGACACTAAGCAGCGAGGTGCCTTGGATGCCACTGAGTTTACCATT GCCATGCATCTACTGACATCATATAAATCTGGCGCCCTGCGCGGTATCCCTGCGACCCTCCCGCCTGGTCTGTAC GATGCGGCAGCTCGCAGGGGACCTCCTGCACGGGTGTCTTTTGGGGCGAGACCCGATGTGCCCCCCATCCCGGCC ATTCCCCAGCAATTTACTGGCCCTCAGCGAACTACAAGCCCTATGAACCAAGCCAATCGCTCCCCCTTTGTAGGC TCTCTTTCCGCCCAGGTCACCGGTGGTGACTGGTTGATTACCCCACAAGAGAAGGCCCAGTTTGATAGCATATTC GAGACTGTTGACACAGCCAAGTTGGGACTTATTACTGGAGACCAAGCTGTATCTTTCTTCATGAAGGCCCAGCTT CCTGAAGAGACGCTTGCCCAAATTTGGGACCTTGCAGATATCGACGCAGACGGCCAGCTGAGCCGGGAAGAATTT GCCGTGGCTATGTACTTGGTGAGATTGCAGCGTAGCGGCAAGGAGCCGCTGCCACAGGTGGTCCCGCCCGCGCTC ATTCCGCCCAATATGCGCCGCCAAGTGCCCGCACCAATGGCAGCCCCCACACCTCCCCCGGCTCCCGCCCCCGTT GTGCGGACAGCTGCTGATGATTTGTTCGGCCTCGATTCGCCCGCGCCGCCATTCGCCCAGCCTCAGATGCCACAG TCTACCGGAGGCTCCAATAGTGCTTTCCAGACTCCAGGCTCGCCTTCCTCTAGGGCATCCCCTCAGACAGCATCG CAAACCTTCAAGCCTTTTATTCCAACCTCTACATTTGGCCAGAGCTTGCAGCCACAGATCACCGGTGCATCGGCG GCAACCCCGAGAGCAGTTCGCTCACCCCCGCCTCCATCGGATGATCTCCTCGGTGACAATGACCCCGAAGAATCA AACAAGTTGACCAATGAGACTACTGAGCTGGCGAACTTGTCCAACCAAATAGGTTCTCTGGCCAAGGAAATGCAC ACTGTGCAGGAGAAGAGGACCTTTGCTGAACAAAGCATTACACAAACCTCGCAGCAGAAGCGTGACTTCGAGGCA CGTCTTGCGCAAGCACGGTCAATGTACGAGCAAGAGGTTACCAATTTCAAAGCACTCGAGGAGCGCCTCAAGTCA TCCAAGGCAGAGACGCAGAAACTGCAGCAGCAATATGCCTTGCTGGATGGCAGCCGCCAGGATTTGCAAAACCAA TACACGCAAGTTTCGACAGCCTTGGCTAGCGATGAGCAGGAGAATTCCAGCCTGAAGGAGAAGATCCGCCAGGCC AATGCTGAAGTTGCCCAGCTCAAGCCGGCACTGGAGAAGGCGCGATCTTCTGCGCGCCAACAGAAGGGTCTTGTT GCCATTAACAAAAAGCAATTAGCTACCGTCGAAGGCGAACGGGACAAGCTCCAGGGTGAAATTGACAGCCTGGCC AATGAGACCCCACAGTATTCCCAAGAGTCTGCAACACCAGCCGGCAGTGTGGCCGATGTTGTAAGCCCTGCTGCC TCTACGACAAGCCAAAACACCAACCCGTTTTTCCGTCGAACTGGTAGCTCGAGTGAACAGGCACGGTCCCCCGAT GTGTCAAATGATCAGCAAAAGGCATTTGACAGCCTCTTCGGACAGCCATTCGCAGCTTTCCCTGCTGCCGGACCA CCACCCACTTCGTTCCGCTCCGAGTCGCCACAGGTTGCAGTCACATCTCCTATTACCTCTGCTGTTACGACCCCA TCAGTCTCTCCTCCCCCTGGCTCTTTGCCTGGTGCATTTCCTTCTGGGGCCTTCTCTGAGCCACCGCCTGCGAGT CAGTCCCGACAACTGACCCCAAACTTCCTGCAGTTCAACGATAATCAGTCTGTGACGTCGTCTACTATGGTCTCG CCTCCTGCGAGTCGATTCGGCGGCGCTGAAACCTCTGGAATCGCTACGCCTTCCCAGGCGGCTAGCAGTGATTAT GGACCTACATCCGGGCCAGAATCTAGCGACTACACGCGTGCACCAACCTCAACTTTTGAAGGCACCCCGGCACGG TCCCCGTTTGAGGAGGAAGGACAAGACCTCTCAGTTAGGTTCCCCGAGCCATCCAAAACCGTTCAGCAGCCCCAA TCTGCAGCAACTCCTGTCGCCAATGAGAGCCAGGTCGAAGACGGCAAGGACCTAAGCTTTGACGAACTGTTCGGC AGCAAGGCACACAAACGGTCTGAATCCCAGCAAGATAACGACTTCGAGGAGGCGTTTGCTTCTATGAAGCCTGTA CCTGGAGCCGAGCAGCCAAATGGAGCTGCATCAGCACGTCCATCCGAATTCCCCCCGATTCAAGAGCTACACCAT GACGATGACGAAGATGAGAGCTCTGATGACGAGGGTGCTTTTGGATTCGAAGATAATTTCACGCCTCCCGCACCA AATGTCCAAAAGGAGACCCAACAGGATTCTATTGACGCCGCTCAGCTGGCTGCTTTCCCTGTCCCGGGAACGTCA AACAAACCCCCATCTCCTGGGGTGCTGCAGAGCCCTCCAGAGTACGAGACAGCTAAAGAAGATAACGTTCATCTT CCTCCTCAATTCAATGGCCTATTGCCCGAGCGCGGCGATCCGACTGTGGCACCGGATGCGCCTCATTCAGTGGAG CACACCACGGGTGCGCCAGTTGTAAGCAATGAGACCAACCGTGATTCTGTCTCGGATGCTGCTATCCCACCCGGT GGAGCGAAGGTGGGAGGACCGGACTTTGAGGCAGCATTTGCGGGAATGAATCTTGCGCCCGCGATCGAAGCGGAT GACGATGACGACGACGAGCCACAGGGTCAGGAGGCCAAAAACACAACTGACTTTGATTTCTCTTTCGACTCCCCG TCCCAGAAGCAGCAAGCTGTCTCCGGTGCCGATGCCCAATCCAGCTCGTCTCAGTTCTTTGCTTTCGACAACAAT ATCCATGCATCCGCCGCCCCGCCGGTCGGATCGCCCAACGGGGGAGAACCCAAGCCGGCTGCGCTGCATGAATGG GACACTCTCTTTGCGCCTCTTGACAACGCCAAGCCTGATATCGGCGAAGACGCGAACGATGCGAAATCCAAGCAG CCCGGATGGGCTCTGAACAACGACACTGGCGATGACCTGATCCTTCAGCGGCTGACCGGCATGGGCTTCACACGG GATGAGTCCTTGGATGCCTTGGAGAAGTATGACTATAACCTTGACAAGGCCGCCGACCATTTGACTTCGAGGACT TGA
Transcript	>Pro_DTO377G3_2|g4563.t1 ATGGCTGATACCGCACAGCGACACCCGAATCTTCACCTCACTCCAGAGGAAAAGCGCGTATTCTTCCAGCTTTTC CAGGCTGCCGATACCACCAATCTCGGGGTCATTACCGGTGAAATCGCCGTTCCATTCTTTGAGAAGACTCACCTA TCCCCGGATACTCTCGGCCTGATTTGGCAAATTGCCGATAAAGAGAACAGGGGCCTCCTGACCCCATCTGGCTTC GGGATTGTTCTGCGGTTAATTGGACATGCCCAAGCTGGCCGTGCACCTTCGGACGAGTTGGCTCTGCAATCTGGC CCTCTGCCTCGTTTTGACGGAATTGTGGTCGACACAACGGCAAGCGTCCCGGAATCCGGAACCAAAAGCCCTCCA CCTGGAGCCAATGGACCTATTCGTGTTCCACCCCTTCAGCCTGATGATGCCAATAAATTCGTCTCGCTGTTCGAG AAGTCGGACGTCAAGAACGGGATGATCTCAGGCGAAATTGCAAAACAGATCTTCGAACGCGCTCGGCTCCCAAAT GAGGTTCTGGGTCGCATCTGGTTTTTGTCTGACACTAAGCAGCGAGGTGCCTTGGATGCCACTGAGTTTACCATT GCCATGCATCTACTGACATCATATAAATCTGGCGCCCTGCGCGGTATCCCTGCGACCCTCCCGCCTGGTCTGTAC GATGCGGCAGCTCGCAGGGGACCTCCTGCACGGGTGTCTTTTGGGGCGAGACCCGATGTGCCCCCCATCCCGGCC ATTCCCCAGCAATTTACTGGCCCTCAGCGAACTACAAGCCCTATGAACCAAGCCAATCGCTCCCCCTTTGTAGGC TCTCTTTCCGCCCAGGTCACCGGTGGTGACTGGTTGATTACCCCACAAGAGAAGGCCCAGTTTGATAGCATATTC GAGACTGTTGACACAGCCAAGTTGGGACTTATTACTGGAGACCAAGCTGTATCTTTCTTCATGAAGGCCCAGCTT CCTGAAGAGACGCTTGCCCAAATTTGGGACCTTGCAGATATCGACGCAGACGGCCAGCTGAGCCGGGAAGAATTT GCCGTGGCTATGTACTTGGTGAGATTGCAGCGTAGCGGCAAGGAGCCGCTGCCACAGGTGGTCCCGCCCGCGCTC ATTCCGCCCAATATGCGCCGCCAAGTGCCCGCACCAATGGCAGCCCCCACACCTCCCCCGGCTCCCGCCCCCGTT GTGCGGACAGCTGCTGATGATTTGTTCGGCCTCGATTCGCCCGCGCCGCCATTCGCCCAGCCTCAGATGCCACAG TCTACCGGAGGCTCCAATAGTGCTTTCCAGACTCCAGGCTCGCCTTCCTCTAGGGCATCCCCTCAGACAGCATCG CAAACCTTCAAGCCTTTTATTCCAACCTCTACATTTGGCCAGAGCTTGCAGCCACAGATCACCGGTGCATCGGCG GCAACCCCGAGAGCAGTTCGCTCACCCCCGCCTCCATCGGATGATCTCCTCGGTGACAATGACCCCGAAGAATCA AACAAGTTGACCAATGAGACTACTGAGCTGGCGAACTTGTCCAACCAAATAGGTTCTCTGGCCAAGGAAATGCAC ACTGTGCAGGAGAAGAGGACCTTTGCTGAACAAAGCATTACACAAACCTCGCAGCAGAAGCGTGACTTCGAGGCA CGTCTTGCGCAAGCACGGTCAATGTACGAGCAAGAGGTTACCAATTTCAAAGCACTCGAGGAGCGCCTCAAGTCA TCCAAGGCAGAGACGCAGAAACTGCAGCAGCAATATGCCTTGCTGGATGGCAGCCGCCAGGATTTGCAAAACCAA TACACGCAAGTTTCGACAGCCTTGGCTAGCGATGAGCAGGAGAATTCCAGCCTGAAGGAGAAGATCCGCCAGGCC AATGCTGAAGTTGCCCAGCTCAAGCCGGCACTGGAGAAGGCGCGATCTTCTGCGCGCCAACAGAAGGGTCTTGTT GCCATTAACAAAAAGCAATTAGCTACCGTCGAAGGCGAACGGGACAAGCTCCAGGGTGAAATTGACAGCCTGGCC AATGAGACCCCACAGTATTCCCAAGAGTCTGCAACACCAGCCGGCAGTGTGGCCGATGTTGTAAGCCCTGCTGCC TCTACGACAAGCCAAAACACCAACCCGTTTTTCCGTCGAACTGGTAGCTCGAGTGAACAGGCACGGTCCCCCGAT GTGTCAAATGATCAGCAAAAGGCATTTGACAGCCTCTTCGGACAGCCATTCGCAGCTTTCCCTGCTGCCGGACCA CCACCCACTTCGTTCCGCTCCGAGTCGCCACAGGTTGCAGTCACATCTCCTATTACCTCTGCTGTTACGACCCCA TCAGTCTCTCCTCCCCCTGGCTCTTTGCCTGGTGCATTTCCTTCTGGGGCCTTCTCTGAGCCACCGCCTGCGAGT CAGTCCCGACAACTGACCCCAAACTTCCTGCAGTTCAACGATAATCAGTCTGTGACGTCGTCTACTATGGTCTCG CCTCCTGCGAGTCGATTCGGCGGCGCTGAAACCTCTGGAATCGCTACGCCTTCCCAGGCGGCTAGCAGTGATTAT GGACCTACATCCGGGCCAGAATCTAGCGACTACACGCGTGCACCAACCTCAACTTTTGAAGGCACCCCGGCACGG TCCCCGTTTGAGGAGGAAGGACAAGACCTCTCAGTTAGGTTCCCCGAGCCATCCAAAACCGTTCAGCAGCCCCAA TCTGCAGCAACTCCTGTCGCCAATGAGAGCCAGGTCGAAGACGGCAAGGACCTAAGCTTTGACGAACTGTTCGGC AGCAAGGCACACAAACGGTCTGAATCCCAGCAAGATAACGACTTCGAGGAGGCGTTTGCTTCTATGAAGCCTGTA CCTGGAGCCGAGCAGCCAAATGGAGCTGCATCAGCACGTCCATCCGAATTCCCCCCGATTCAAGAGCTACACCAT GACGATGACGAAGATGAGAGCTCTGATGACGAGGGTGCTTTTGGATTCGAAGATAATTTCACGCCTCCCGCACCA AATGTCCAAAAGGAGACCCAACAGGATTCTATTGACGCCGCTCAGCTGGCTGCTTTCCCTGTCCCGGGAACGTCA AACAAACCCCCATCTCCTGGGGTGCTGCAGAGCCCTCCAGAGTACGAGACAGCTAAAGAAGATAACGTTCATCTT CCTCCTCAATTCAATGGCCTATTGCCCGAGCGCGGCGATCCGACTGTGGCACCGGATGCGCCTCATTCAGTGGAG CACACCACGGGTGCGCCAGTTGTAAGCAATGAGACCAACCGTGATTCTGTCTCGGATGCTGCTATCCCACCCGGT GGAGCGAAGGTGGGAGGACCGGACTTTGAGGCAGCATTTGCGGGAATGAATCTTGCGCCCGCGATCGAAGCGGAT GACGATGACGACGACGAGCCACAGGGTCAGGAGGCCAAAAACACAACTGACTTTGATTTCTCTTTCGACTCCCCG TCCCAGAAGCAGCAAGCTGTCTCCGGTGCCGATGCCCAATCCAGCTCGTCTCAGTTCTTTGCTTTCGACAACAAT ATCCATGCATCCGCCGCCCCGCCGGTCGGATCGCCCAACGGGGGAGAACCCAAGCCGGCTGCGCTGCATGAATGG GACACTCTCTTTGCGCCTCTTGACAACGCCAAGCCTGATATCGGCGAAGACGCGAACGATGCGAAATCCAAGCAG CCCGGATGGGCTCTGAACAACGACACTGGCGATGACCTGATCCTTCAGCGGCTGACCGGCATGGGCTTCACACGG GATGAGTCCTTGGATGCCTTGGAGAAGTATGACTATAACCTTGACAAGGCCGCCGACCATTTGACTTCGAGGACT TGA
Gene	>Pro_DTO377G3_2|g4563.t1 ATGGCTGATACCGGTAAGTAATACTTAATATTCCTTGCTAGAGCCAATACGAATCGTGAGAGAGCTTCGGCGCAC TCAAGGGAAACGCCCGCCGACCTCCGTCATCACCACCCCTCCCCTTCTTGCACTCGCACTCTATATGCGCGATCT AGCGGAGCTGACGGAACACAATCTTTTAGCACAGCGACACCCGAATCTTCACCTCACTCCAGAGGAAAAGCGCGT ATTCTTCCAGCTTTTCCAGGCTGCCGATACCACCAATCTCGGGGTCATTACCGGTGAAATCGCCGTTCCATTCTT TGAGAAGACTCACCTATCCCCGGATACTCTCGGCCTGGTATGTGGATAGAATATGGGTGTTAGATCGCAATAGTG AGAGGGATAGCTAATGAGTGGTCTTGTAGATTTGGCAAATTGCCGATAAAGAGAACAGGGGCCTCCTGACCCCAT CTGGCTTCGGGATTGTTCTGCGGTTAATTGGACATGCCCAAGCTGGCCGTGCACCTTCGGACGAGTTGGCTCTGC AATGTGAGTGATGTTCCCTTCAGAGAAGTGGAATCCATGCTGATCGCGCACCTATTCATAGCTGGCCCTCTGCCT CGTTTTGACGGAATTGTGGTCGACACAACGGCAAGCGTCCCGGAATCCGGAACCAAAAGCCCTCCACCTGGAGCC AATGGACCTATTCGTGTTCCACCCCTTCAGCCTGATGATGCCAATAAATTCGTCTCGCTGTTCGAGAAGTCGGAC GTCAAGAACGGGATGATCTCAGGTATGTAGCTCTTCCCTGCAGATAAGGTGCCAATCTCACAAGTTCGCTGTTTG ATCTATAGGCGAAATTGCAAAACAGATCTTCGAACGCGCTCGGCTCCCAAATGAGGTTCTGGGTCGCATCTGGTT TTTGTCTGACACTAAGCAGCGAGGTGCCTTGGATGCCACTGAGTTTACCATTGCCATGCATCTACTGACATCATA TAAATCTGGCGCCCTGCGCGGTATCCCTGCGACCCTCCCGCCTGGTCTGTACGATGCGGCAGCTCGCAGGGGACC TCCTGCACGGGTGTCTTTTGGGGCGAGACCCGATGTGCCCCCCATCCCGGCCATTCCCCAGCAATTTACTGGCCC TCAGCGAACTACAAGCCCTATGAACCAAGCCAATCGCTCCCCCTTTGTAGGCTCTCTTTCCGCCCAGGTCACCGG TGGTGACTGGTTGATTACCCCACAAGAGAAGGCCCAGTTTGATAGCATATTCGAGACTGTTGACACAGCCAAGTT GGGACTTATTACTGGAGACCAAGCTGTATCTTTCTTCATGAAGGCCCAGCTTCCTGAAGAGACGCTTGCCCAAAT TTGGGACCTTGCAGATATCGACGCAGACGGCCAGCTGAGCCGGGAAGAATTTGCCGTGGCTATGTACTTGGTGAG ATTGCAGCGTAGCGGCAAGGAGCCGCTGCCACAGGTGGTCCCGCCCGCGCTCATTCCGCCCAATATGCGCCGCCA AGTGCCCGCACCAATGGCAGCCCCCACACCTCCCCCGGCTCCCGCCCCCGTTGTGCGGACAGCTGCTGATGATTT GTTCGGCCTCGATTCGCCCGCGCCGCCATTCGCCCAGCCTCAGATGCCACAGTCTACCGGAGGCTCCAATAGTGC TTTCCAGACTCCAGGCTCGCCTTCCTCTAGGGCATCCCCTCAGACAGCATCGCAAACCTTCAAGCCTTTTATTCC AACCTCTACATTTGGCCAGAGCTTGCAGCCACAGATCACCGGTGCATCGGCGGCAACCCCGAGAGCAGTTCGCTC ACCCCCGCCTCCATCGGATGATCTCCTCGGTGACAATGACCCCGAAGAATCAAACAAGTTGACCAATGAGACTAC TGAGCTGGCGAACTTGTCCAACCAAATAGGTTCTCTGGCCAAGGAAATGCACACTGTGCAGGAGAAGAGGACCTT TGCTGAACAAAGCATTACACAAACCTCGCAGCAGAAGCGTGACTTCGAGGCACGTCTTGCGCAAGCACGGTCAAT GTACGAGCAAGAGGTTACCAATTTCAAAGCACTCGAGGAGCGCCTCAAGTCATCCAAGGCAGAGACGCAGAAACT GCAGCAGCAATATGCCTTGCTGGATGGCAGCCGCCAGGATTTGCAAAACCAATACACGCAAGTTTCGACAGCCTT GGCTAGCGATGAGCAGGAGAATTCCAGCCTGAAGGAGAAGATCCGCCAGGCCAATGCTGAAGTTGCCCAGCTCAA GCCGGCACTGGAGAAGGCGCGATCTTCTGCGCGCCAACAGAAGGGTCTTGTTGCCATTAACAAAAAGCAATTAGC TACCGTCGAAGGCGAACGGGACAAGCTCCAGGGTGAAATTGACAGCCTGGCCAATGAGACCCCACAGTATTCCCA AGAGTCTGCAACACCAGCCGGCAGTGTGGCCGATGTTGTAAGCCCTGCTGCCTCTACGACAAGCCAAAACACCAA CCCGTTTTTCCGTCGAACTGGTAGCTCGAGTGAACAGGCACGGTCCCCCGATGTGTCAAATGATCAGCAAAAGGC ATTTGACAGCCTCTTCGGACAGCCATTCGCAGCTTTCCCTGCTGCCGGACCACCACCCACTTCGTTCCGCTCCGA GTCGCCACAGGTTGCAGTCACATCTCCTATTACCTCTGCTGTTACGACCCCATCAGTCTCTCCTCCCCCTGGCTC TTTGCCTGGTGCATTTCCTTCTGGGGCCTTCTCTGAGCCACCGCCTGCGAGTCAGTCCCGACAACTGACCCCAAA CTTCCTGCAGTTCAACGATAATCAGTCTGTGACGTCGTCTACTATGGTCTCGCCTCCTGCGAGTCGATTCGGCGG CGCTGAAACCTCTGGAATCGCTACGCCTTCCCAGGCGGCTAGCAGTGATTATGGACCTACATCCGGGCCAGAATC TAGCGACTACACGCGTGCACCAACCTCAACTTTTGAAGGCACCCCGGCACGGTCCCCGTTTGAGGAGGAAGGACA AGACCTCTCAGTTAGGTTCCCCGAGCCATCCAAAACCGTTCAGCAGCCCCAATCTGCAGCAACTCCTGTCGCCAA TGAGAGCCAGGTCGAAGACGGCAAGGACCTAAGCTTTGACGAACTGTTCGGCAGCAAGGCACACAAACGGTCTGA ATCCCAGCAAGATAACGACTTCGAGGAGGCGTTTGCTTCTATGAAGCCTGTACCTGGAGCCGAGCAGCCAAATGG AGCTGCATCAGCACGTCCATCCGAATTCCCCCCGATTCAAGAGCTACACCATGACGATGACGAAGATGAGAGCTC TGATGACGAGGGTGCTTTTGGATTCGAAGATAATTTCACGCCTCCCGCACCAAATGTCCAAAAGGAGACCCAACA GGATTCTATTGACGCCGCTCAGCTGGCTGCTTTCCCTGTCCCGGGAACGTCAAACAAACCCCCATCTCCTGGGGT GCTGCAGAGCCCTCCAGAGTACGAGACAGCTAAAGAAGATAACGTTCATCTTCCTCCTCAATTCAATGGCCTATT GCCCGAGCGCGGCGATCCGACTGTGGCACCGGATGCGCCTCATTCAGTGGAGCACACCACGGGTGCGCCAGTTGT AAGCAATGAGACCAACCGTGATTCTGTCTCGGATGCTGCTATCCCACCCGGTGGAGCGAAGGTGGGAGGACCGGA CTTTGAGGCAGCATTTGCGGGAATGAATCTTGCGCCCGCGATCGAAGCGGATGACGATGACGACGACGAGCCACA GGGTCAGGAGGCCAAAAACACAACTGACTTTGATTTCTCTTTCGACTCCCCGTCCCAGAAGCAGCAAGCTGTCTC CGGTGCCGATGCCCAATCCAGCTCGTCTCAGTTCTTTGCTTTCGACAACAATATCCATGCATCCGCCGCCCCGCC GGTCGGATCGCCCAACGGGGGAGAACCCAAGCCGGCTGCGCTGCATGAATGGGACACTCTCTTTGCGCCTCTTGA CAACGCCAAGCCTGATATCGGCGAAGACGCGAACGATGCGAAATCCAAGCAGCCCGGATGGGCTCTGAACAACGA CACTGGCGATGACCTGATCCTTCAGCGGCTGACCGGCATGGGCTTCACACGGGATGAGTCCTTGGATGCCTTGGA GAAGTATGACTATAACCTTGACAAGGTAAATTGCCTTCCACATTCTGTTTTACATCATACTAACTAAAGACTAGG CCGCCGACCATTTGACTTCGAGGACTTGA