Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g408.t1
Gene name
Location	scaffold_01:1036358..1040961
Strand	+
Gene length (bp)	4603
Transcript length (bp)	2619
Coding sequence length (bp)	2619
Protein length (aa)	873

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00664	ABC_membrane	ABC transporter transmembrane region	1.0E-13	604	730
PF05047	L51_S25_CI-B8	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain	7.9E-14	43	90
PF00005	ABC_tran	ABC transporter	4.4E-08	320	438

GO

GO Term	Description	Terminal node
GO:0005524	ATP binding	Yes
GO:0016021	integral component of membrane	Yes
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	Yes
GO:0016887	ATPase activity	Yes
GO:0055085	transmembrane transport	Yes
GO:0016462	pyrophosphatase activity	No
GO:1901265	nucleoside phosphate binding	No
GO:0017111	nucleoside-triphosphatase activity	No
GO:0022804	active transmembrane transporter activity	No
GO:0043168	anion binding	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0003824	catalytic activity	No
GO:0032553	ribonucleotide binding	No
GO:0097367	carbohydrate derivative binding	No
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	No
GO:0043492	ATPase activity, coupled to movement of substances	No
GO:0051234	establishment of localization	No
GO:0097159	organic cyclic compound binding	No
GO:0032555	purine ribonucleotide binding	No
GO:1901363	heterocyclic compound binding	No
GO:0051179	localization	No
GO:0005215	transporter activity	No
GO:0031224	intrinsic component of membrane	No
GO:0003674	molecular_function	No
GO:0036094	small molecule binding	No
GO:0016817	hydrolase activity, acting on acid anhydrides	No
GO:0044425	membrane part	No
GO:0005488	binding	No
GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0015399	primary active transmembrane transporter activity	No
GO:0043167	ion binding	No
GO:0042623	ATPase activity, coupled	No
GO:0017076	purine nucleotide binding	No
GO:0000166	nucleotide binding	No
GO:0008144	drug binding	No
GO:0008150	biological_process	No
GO:0016787	hydrolase activity	No
GO:0006810	transport	No
GO:0005575	cellular_component	No
GO:0030554	adenyl nucleotide binding	No
GO:0022857	transmembrane transporter activity	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	190	212	22
2	227	249	22
3	443	462	19
4	529	551	22
5	556	575	19
6	614	636	22
7	706	728	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g408.t1 MPLRGIRTSTAARNGAGAFILQCKRLDFHYCNWAGSSKGMVTFLEKHLPAFARENPQIEIRVSPRPQKHPLIKGL YINGREKPVCVRNLEPHEILKKAILLKEASGEKLKRVKKPVTMSVLGSSYIAPQMRQKQKAWVHAVQERVNFTSI MLKELRQIKMFGIESDVAFKTNGLRELELHQSKPYRSMIVGVNVLSALSTAIAPALTIAMYATTQLNLRLETPST DVAFTNLSLISLLTNPVVLLSVSLTRFTSAIGCFDRIQEFFCKKNRVHGLSSVDEYLLPENVLGMEPESVPTQSQ PLVCMTDCCFSLGLEAPAILHGLTLKIQNGFFLAVTAPLGSGKSSLLKDMLGEMHSTEGILTVRSVKQAYCQQAP WIFNGTLRTNTIGESPLDETWFKEVVYVCNLDFETTTLSLGLDTLTGSSGAELSGGQKQRVRLLDRAGLVRRLGI ATILVTTAVEHLKEADNLIVLSKDGRMECQGLFEELAKKNQYIQSLLCSPSPEDSEVEEESKDNRFQNLQGDGDT SLYTFGWWACGLTLAFTILYVFCIAFPQVMLSWWFAMGVFIGFFFVWTVPRSAVKLHEVFLGTIMRSPWPSLARI YTGSFLTCIAQGDLIATGSGFMSVIIPFCIVAVWIIQAFYLRTSRQIRLLDLEAKAPLYAHFIETTEGLTTVRAL CWQRQFADRNTELLDTSQKPFYTMYSIQQWLQVVLDLLVAGLATVLVSLAVFVTKQSSSGAVVLETSLGAIARVK QFVTDPQLQPIARREMAYLKRWPSEGRMEFRRVSASYGGHDSVPAVRDISFTLEVGRVLYLLAFSLSRRSRPAKS TLTALTSQPFPRKSFILHWSQYPKIPKSPDSSRFCSPKYFLGNIIND*
Coding	>Pro_DTO377G3_2|g408.t1 ATGCCGTTGCGCGGAATTAGAACATCTACGGCGGCCAGGAACGGCGCCGGTGCCTTCATCCTACAATGCAAACGC CTTGACTTCCATTACTGCAACTGGGCGGGCAGCTCAAAGGGCATGGTTACTTTCTTAGAGAAACACCTCCCCGCT TTCGCCCGCGAGAACCCTCAGATTGAAATCCGTGTCTCTCCCCGACCCCAGAAGCACCCCCTGATTAAGGGCCTT TATATCAATGGCCGTGAGAAGCCCGTGTGTGTACGGAACTTGGAACCTCACGAAATCCTGAAGAAGGCAATTCTC CTCAAAGAAGCTAGTGGAGAGAAGTTGAAGCGGGTCAAGAAGCCAGTCACAATGAGCGTACTAGGATCATCCTAT ATCGCCCCTCAAATGCGCCAAAAGCAAAAGGCTTGGGTACATGCTGTTCAGGAGAGAGTCAATTTTACTTCGATA ATGCTGAAAGAGCTGCGCCAGATCAAAATGTTCGGTATTGAATCAGACGTGGCATTCAAGACAAACGGTCTTCGT GAGTTGGAACTCCATCAATCAAAGCCCTACCGATCAATGATTGTCGGTGTCAATGTTTTGAGTGCGTTGTCGACT GCCATCGCCCCTGCCCTAACAATAGCCATGTACGCCACTACACAGCTGAACCTCAGGCTAGAGACACCCAGTACT GATGTTGCCTTCACAAATCTGTCCTTAATTTCTCTTTTGACAAACCCGGTAGTACTACTATCTGTCTCCTTGACT AGATTCACATCCGCTATTGGCTGTTTTGATCGGATTCAAGAATTTTTTTGCAAGAAAAACCGAGTACATGGGCTC TCATCTGTCGATGAATACTTGCTGCCTGAGAACGTGTTAGGGATGGAACCCGAATCAGTGCCGACTCAGTCACAA CCTCTTGTCTGCATGACTGATTGCTGCTTTAGCCTGGGCTTAGAGGCTCCAGCAATACTCCATGGACTAACTTTG AAGATCCAAAATGGTTTTTTTTTGGCTGTGACTGCCCCCCTTGGCTCTGGCAAGTCATCTTTACTCAAAGATATG CTGGGTGAAATGCATTCTACGGAAGGAATATTGACTGTTCGTTCGGTCAAACAGGCGTATTGCCAGCAAGCTCCA TGGATATTCAATGGCACACTAAGAACTAACACTATCGGAGAATCACCACTCGACGAAACGTGGTTCAAAGAGGTG GTATATGTCTGCAACCTGGATTTTGAAACCACAACTCTTTCTCTTGGACTTGACACACTGACTGGGAGCTCGGGA GCTGAACTTAGTGGAGGGCAGAAGCAACGAGTGCGACTCCTCGATCGTGCTGGCTTGGTCAGGAGGCTGGGTATC GCAACCATTCTTGTGACAACAGCTGTGGAACACCTCAAAGAAGCCGATAATTTGATTGTTCTTTCAAAGGACGGT CGCATGGAATGTCAAGGACTTTTCGAAGAACTGGCGAAGAAGAATCAGTACATACAGAGTCTTTTGTGTTCCCCA AGTCCGGAAGACAGTGAAGTCGAAGAAGAGAGCAAGGACAACCGTTTCCAAAATCTCCAGGGTGATGGGGACACC TCACTCTACACGTTTGGTTGGTGGGCATGTGGGCTAACGCTGGCATTCACAATTCTATACGTGTTTTGTATTGCA TTTCCGCAGGTCATGCTTAGCTGGTGGTTTGCGATGGGGGTTTTTATCGGGTTCTTTTTTGTCTGGACTGTTCCC AGATCGGCTGTTAAGCTGCATGAGGTCTTCTTGGGTACAATAATGAGATCGCCTTGGCCGAGCCTGGCTCGCATA TATACAGGAAGCTTTTTGACCTGTATTGCACAAGGGGACTTGATCGCTACTGGATCAGGCTTCATGTCTGTCATA ATACCCTTCTGCATCGTTGCGGTATGGATAATTCAGGCTTTCTACTTGCGTACTTCACGACAGATCAGACTTCTC GATCTAGAAGCAAAGGCTCCTCTGTATGCCCACTTCATAGAAACGACAGAGGGTCTAACTACTGTGCGTGCACTT TGTTGGCAGCGTCAATTTGCAGATCGGAACACCGAGCTCCTCGATACGTCCCAGAAACCATTTTACACCATGTAT TCCATTCAGCAGTGGTTGCAGGTTGTTTTGGATCTACTTGTTGCGGGCCTTGCCACCGTTCTTGTTTCCCTAGCT GTTTTTGTGACAAAGCAAAGTAGCTCTGGGGCCGTCGTTCTTGAGACTTCTCTAGGCGCAATTGCAAGGGTCAAG CAATTTGTGACTGACCCACAGCTACAACCTATTGCCAGAAGAGAGATGGCTTATCTCAAGCGCTGGCCTTCGGAA GGTCGAATGGAATTTCGAAGGGTTTCTGCTTCATATGGGGGGCATGATTCCGTTCCAGCTGTGCGGGATATCTCA TTTACACTGGAAGTGGGAAGAGTTCTTTACTTGCTTGCATTTTCTCTCTCGCGACGATCACGTCCGGCGAAATCT ACATTGACGGCATTGACATCTCAACCGTTCCCAAGGAAAAGCTTCATTCTGCATTGGTCCCAATATCCCAAAATC CCAAAATCCCCTGATTCTTCCCGGTTCTGTTCGCCAAAATATTTCCTTGGGAATATCATCAACGATTGA
Transcript	>Pro_DTO377G3_2|g408.t1 ATGCCGTTGCGCGGAATTAGAACATCTACGGCGGCCAGGAACGGCGCCGGTGCCTTCATCCTACAATGCAAACGC CTTGACTTCCATTACTGCAACTGGGCGGGCAGCTCAAAGGGCATGGTTACTTTCTTAGAGAAACACCTCCCCGCT TTCGCCCGCGAGAACCCTCAGATTGAAATCCGTGTCTCTCCCCGACCCCAGAAGCACCCCCTGATTAAGGGCCTT TATATCAATGGCCGTGAGAAGCCCGTGTGTGTACGGAACTTGGAACCTCACGAAATCCTGAAGAAGGCAATTCTC CTCAAAGAAGCTAGTGGAGAGAAGTTGAAGCGGGTCAAGAAGCCAGTCACAATGAGCGTACTAGGATCATCCTAT ATCGCCCCTCAAATGCGCCAAAAGCAAAAGGCTTGGGTACATGCTGTTCAGGAGAGAGTCAATTTTACTTCGATA ATGCTGAAAGAGCTGCGCCAGATCAAAATGTTCGGTATTGAATCAGACGTGGCATTCAAGACAAACGGTCTTCGT GAGTTGGAACTCCATCAATCAAAGCCCTACCGATCAATGATTGTCGGTGTCAATGTTTTGAGTGCGTTGTCGACT GCCATCGCCCCTGCCCTAACAATAGCCATGTACGCCACTACACAGCTGAACCTCAGGCTAGAGACACCCAGTACT GATGTTGCCTTCACAAATCTGTCCTTAATTTCTCTTTTGACAAACCCGGTAGTACTACTATCTGTCTCCTTGACT AGATTCACATCCGCTATTGGCTGTTTTGATCGGATTCAAGAATTTTTTTGCAAGAAAAACCGAGTACATGGGCTC TCATCTGTCGATGAATACTTGCTGCCTGAGAACGTGTTAGGGATGGAACCCGAATCAGTGCCGACTCAGTCACAA CCTCTTGTCTGCATGACTGATTGCTGCTTTAGCCTGGGCTTAGAGGCTCCAGCAATACTCCATGGACTAACTTTG AAGATCCAAAATGGTTTTTTTTTGGCTGTGACTGCCCCCCTTGGCTCTGGCAAGTCATCTTTACTCAAAGATATG CTGGGTGAAATGCATTCTACGGAAGGAATATTGACTGTTCGTTCGGTCAAACAGGCGTATTGCCAGCAAGCTCCA TGGATATTCAATGGCACACTAAGAACTAACACTATCGGAGAATCACCACTCGACGAAACGTGGTTCAAAGAGGTG GTATATGTCTGCAACCTGGATTTTGAAACCACAACTCTTTCTCTTGGACTTGACACACTGACTGGGAGCTCGGGA GCTGAACTTAGTGGAGGGCAGAAGCAACGAGTGCGACTCCTCGATCGTGCTGGCTTGGTCAGGAGGCTGGGTATC GCAACCATTCTTGTGACAACAGCTGTGGAACACCTCAAAGAAGCCGATAATTTGATTGTTCTTTCAAAGGACGGT CGCATGGAATGTCAAGGACTTTTCGAAGAACTGGCGAAGAAGAATCAGTACATACAGAGTCTTTTGTGTTCCCCA AGTCCGGAAGACAGTGAAGTCGAAGAAGAGAGCAAGGACAACCGTTTCCAAAATCTCCAGGGTGATGGGGACACC TCACTCTACACGTTTGGTTGGTGGGCATGTGGGCTAACGCTGGCATTCACAATTCTATACGTGTTTTGTATTGCA TTTCCGCAGGTCATGCTTAGCTGGTGGTTTGCGATGGGGGTTTTTATCGGGTTCTTTTTTGTCTGGACTGTTCCC AGATCGGCTGTTAAGCTGCATGAGGTCTTCTTGGGTACAATAATGAGATCGCCTTGGCCGAGCCTGGCTCGCATA TATACAGGAAGCTTTTTGACCTGTATTGCACAAGGGGACTTGATCGCTACTGGATCAGGCTTCATGTCTGTCATA ATACCCTTCTGCATCGTTGCGGTATGGATAATTCAGGCTTTCTACTTGCGTACTTCACGACAGATCAGACTTCTC GATCTAGAAGCAAAGGCTCCTCTGTATGCCCACTTCATAGAAACGACAGAGGGTCTAACTACTGTGCGTGCACTT TGTTGGCAGCGTCAATTTGCAGATCGGAACACCGAGCTCCTCGATACGTCCCAGAAACCATTTTACACCATGTAT TCCATTCAGCAGTGGTTGCAGGTTGTTTTGGATCTACTTGTTGCGGGCCTTGCCACCGTTCTTGTTTCCCTAGCT GTTTTTGTGACAAAGCAAAGTAGCTCTGGGGCCGTCGTTCTTGAGACTTCTCTAGGCGCAATTGCAAGGGTCAAG CAATTTGTGACTGACCCACAGCTACAACCTATTGCCAGAAGAGAGATGGCTTATCTCAAGCGCTGGCCTTCGGAA GGTCGAATGGAATTTCGAAGGGTTTCTGCTTCATATGGGGGGCATGATTCCGTTCCAGCTGTGCGGGATATCTCA TTTACACTGGAAGTGGGAAGAGTTCTTTACTTGCTTGCATTTTCTCTCTCGCGACGATCACGTCCGGCGAAATCT ACATTGACGGCATTGACATCTCAACCGTTCCCAAGGAAAAGCTTCATTCTGCATTGGTCCCAATATCCCAAAATC CCAAAATCCCCTGATTCTTCCCGGTTCTGTTCGCCAAAATATTTCCTTGGGAATATCATCAACGATTGA
Gene	>Pro_DTO377G3_2|g408.t1 ATGCCGTTGCGCGGAATTAGAACATCTACGGCGGCCAGGGTATGTGAAGTCCGAATGTTTGATATTCAATTGACG AACTGACCCAAATCTGCTTAGAACGGCGCCGGTGCCTTCATCCTACAATGCAAACGCCTTGACTTCCATTACTGC AACTGGGCGGGCAGCTCAAAGGGCATGGTGTAGGTGTATCCTAAATGGTGAAACTGAAACTTTCCAGAAACATCC GTACTAACATTGAACATCGCAGTACTTTCTTAGAGAAACACCTCCCCGCTTTCGCCCGCGAGAACCCTCAGATTG AAATCCGTGTCTCTCCCCGACCCCAGAAGCACCCCCTGATTAAGGGCCTTTATATCAATGGCCGTGAGAAGCCCG TGTGTGTACGGAACTTGGAACCTCACGAAATCCTGAAGAAGGCAATTCTCCTCAAAGAAGCTAGTGGAGAGAAGT TGAAGCGGGTCAAGAAGCCAGTCACAAGTTTGAATGAGAGTGTGCGTGGTATCTGGTCACCATACCACGGTGATC TTCGGGGAGTCTAGACGGTTGTATTTTATTATTTACGGTTCATGTTCTCTCTGCGGTGGTGACTATCAGGTATCC CCACTGCAACCTACTGTACTATTGACCTGGGTTGTGTTTATTTCTTCGTTCTTGTCTATTTGCTCCCTGGAAGCC AATGGTGTTTTGAAACCCATATTTTATGCATACAAAACTTGAGCCTATATCAATTCTCTTCCATGATTTCTCTAT ACCGGAGGTCACCGAAAGTTTGGCTTAACTCCGGACTCCGGGATACTTCTTTCATCCAAATCCGATGGTCACATA TCTTATTAGCCTGATTTGGATTTGAAAGCATACATACGTGCCTAACAAGGCTGGTGTTGGCTAGCTTATTGCATG GTTCGCAATCTACTTGACCGGGGGCTCGGCTTTTGCCAGTGTTCGCCCATCCCCTAGTTTTCTACCTGCGTAATC CTCTTCCCTCACTCTCATATTTCATATTTCATCTGAGCGCCTTACTTGCGAAAAAGTGAAGATGCAGTGTGGCAT TTCTGCCGACACTCACTTTGGACCCCGAGTGCTGCCATGCCGTCGCGATTTCGACTTTACGTTGCTCTTCGAGCA GGGCATTCTCGCTTTGGCTCCGCATCTTTTATTCCTCACTCTGTGCATTTTCAGTGGTATCATTTCCACAGAGAG CCCAGGAAAGTACACGTAGTGCTGCTGGCACTTGGAAAGTGGTAGGTCTCCCTTTTCCTTAGCTCCGAAATTAGG CTTGCAAGCTAATGTGATATTGAAATATCAAGCAGGTCATTTCCACTCTACTACTAGCTCCGAAACTTGTTCTCC TCGTTTGTGGTGTTTACCAAACTCTCCAAGAACAAAGCTCTCGGTTCCGTCTCAAAGAAAGGAACTAATCGAAAT ATAGTGAGCGTACTAGGATCATCCTATATCGCCCCTCAAATGCGCCAAAAGCAAAAGGCTTGGGTACATGCTGTT CAGGAGAGAGTCAATTTTACTTCGATAATGCTGAAAGAGCTGCGCCAGATCAAAATGTTCGGTATTGAATCAGAC GTGGCATTCAAGACAAACGGTCTTCGTGAGTTGGAACTCCATCAATCAAAGCCCTACCGATCAATGATTGTCGGT GTCAATGTTTTGAGTGCGTTGTCGACTGCCATCGCCCCTGCCCTAACAATAGCCATGTACGCCACTACACAGCTG AACCTCAGGCTAGAGACACCCAGTACTGATGTTGCCTTCACAAATCTGTCCTTAATTTCTCTTTTGACAAACCCG GTAGTACTACTATCTGTCTCCTTGACTAGATTCACATCCGCTATTGGCTGTTTTGATCGGATTCAAGAATTTTTT TGCAAGAAAAACCGAGTACATGGGCTCTCATCTGTCGATGAATACTTGCTGCCTGAGAACGTGTTAGGGATGGAA CCCGAATCAGTGCCGACTCAGTCACAACCTCTTGTCTGCATGACTGATTGCTGCTTTAGCCTGGGCTTAGAGGCT CCAGCAATACTCCATGGACTAACTTTGAAGATCCAAAATGGTTTTTTTTTGGCTGTGACTGCCCCCCTTGGCTCT GGCAAGTCATCTTTACTCAAAGATATGCTGGGTGAAATGCATTCTACGGAAGGAATATTGACTGTTCGTTCGGTC AAACAGGCGTATTGCCAGCAAGCTCCATGGATATTCAATGGCACACTAAGAACTAACACTATCGGAGAATCACCA CTCGACGAAACGTGGTTCAAAGAGGTGGTATATGTCTGCAACCTGGATTTTGAAACCACAACTCTTTCTCTTGGA CTTGACACACTGACTGGGAGCTCGGGAGCTGAACTTAGTGGAGGGCAGAAGCAACGAGTGGTAAGTATATCGGTA ATCTCATTCCATCTTAGGTACTAATTTGCGTGAGTTCAGGCTTTGGCTAGAGCAATTTATGCAAGATCATCTTTG CTGATTTTAGACGACATATTTGGCGCCTTGGACACAGTGACATCAAGGCTAATTTTCCAGCGACTCCTCGATCGT GCTGGCTTGGTCAGGAGGCTGGGTATCGCAACCATTCTTGTGACAACAGCTGGTTAGTCTAACTTGAACCCTTCA AATGCTTACGGCGCTGACCATTGCCTTTATTTCACTAGTGGAACACCTCAAAGAAGCCGATAATTTGATTGTTCT TTCAAAGGACGGTCGCATGGAATGTCAAGGACTTTTCGAAGAACTGGCGAAGAAGAATCAGTACATACAGAGTCT TTTGTGTTCCCCAAGTCCGGAAGACAGTGAAGTCGAAGAAGAGAGCAAGGACAGTAACTCCCAGGTGGGGGAAAT ACGAGAAGAGAAGAAAGAAACCAGACAAACAACTCAAACAAAGACCGTTTCCAAAATCTCCAGGGTGATGGGGAC ACCTCACTCTACACGTTTGGTTGGTGGGCATGTGGGCTAACGCTGGCATTCACAATTCTATACGTGTTTTGTATT GCATTTCCGCGTGAGTATACCCATCACTGGATATATTCAGAGACATTGTTCCTAAATCATATCGCAGAGGTCATG CTTAGCTGGTGGTGTGACTCAGCTCCTCCAAAAAAATTATATTTATCTTGGTTCCTACGTCGGCATTTCTTCCAT CGCCATAGTTGCGATGGGGGTTTTTATCGGGTATGTTCTCAGCACTGCGACGCTATATATGTATGGAGACATCTC ATATATCTTAGGTTCTTTTTTGTCTGGACTGTTCCCAGATCGGCTGTTAAGCTGCATGAGGTCTTCTTGGGTACA ATAATGAGGTCAGGAATGGGGACAGACTCCTTTTATATTAGACTGAATATGTTGCTGACGAGCTTTTCAGATCGC CTTGGCCGAGCCTGGCTCGCATATATACAGGAAGTTTGATAAATAGATAAGCCATATAATTGAGACTCAACGTTG TGATTTCATCGAAATTAACCTGAAAAATTCTAAACATCTCCAGATTTAGCCAAGACATGTCTCTTCTCGACATGC AGCTTCCTGTTGCTTTTGGCATAACTCCCCAGAGAGCGAATCTTCGTTCCCCAGCATTCACAAATTGTTAAATAC TGACTTTCTATCGAGTAGGCTTTTTGACCTGTATTGCACAAGGGGACTTGATCGCTACTGGATCAGGCTTCATGT CTGTCATAATACCCTTCTGCATCGTTGCGGTATGGATAATTCAGGCTTTCTACTTGCGTACTTCACGACAGATCA GACTTCTCGATCTAGAAGCAAAGGCTCCTCTGTATGCCCACTTCATAGAAACGACAGAGGGTCTAACTACTGTGC GTGCACTTTGTTGGCAGCGTCAATTTGCAGATCGGAACACCGAGCTCCTCGATACGTCCCAGAAACCATTTTACA CCATGTATTCCATTCAGCAGTGGTTGCAGGTTGTTTTGGATCTACTTGTTGCGGGCCTTGCCACCGTTCTTGTTT CCCTAGCTGTTTTTGTGACAAAGCAAAGTAGCTCTGGGGCCGTCGTTGTGAACTTATTTCATTCAACTCAACTTT GACATTGTTGATTACTAATTGGACACAGCTTGAGACTTCTCTAGGCGCAATTGCAAGGGTCAAGCAATTTGTGAC TGACCCACAGCTACAACCTATTGCCAGAAGAGAGATGGCTTATCTCAAGCGCTGGCCTTCGGAAGGTCGAATGGA ATTTCGAAGGGTTTCTGCTTCATATGGGTAAGTGTCTCTTTCAGCATCACTCTGTTACGCAAATAGAAATGAACC AAAGGACTAAGATTGCTATTAGGGGGCATGATTCCGTTCCAGCTGTGCGGGATATCTCATTTACACTGGAAGGTA AGGATGGATAAGCTTTATGAATGAGGCATAAGTGATAAGTTGAATAGTGGGAAGAGTTCTTTACTTGCTTGCATT TTCTCTCTCGCGACGATCACGTCCGGCGAAATCTACATTGACGGCATTGACATCTCAACCGTTCCCAAGGAAAAG CTTCATTCTGCATTGGTCCCAATATCCCAAAATCCCAAAATCCCCTGATTCTTCCCGGTTCTGTTCGCCAAAATA TTTCCTTGGGAATATCATCAACGATTGA