Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g4054.t1
Gene name
Location	scaffold_07:646780..650803
Strand	-
Gene length (bp)	4023
Transcript length (bp)	3702
Coding sequence length (bp)	3702
Protein length (aa)	1234

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00704	Glyco_hydro_18	Glycosyl hydrolases family 18	1.1E-62	159	500
PF00187	Chitin_bind_1	Chitin recognition protein	7.8E-10	114	144

GO

GO Term	Description	Terminal node
GO:0005975	carbohydrate metabolic process	Yes
GO:0008061	chitin binding	Yes
GO:0097367	carbohydrate derivative binding	No
GO:0008150	biological_process	No
GO:0044238	primary metabolic process	No
GO:0005488	binding	No
GO:0008152	metabolic process	No
GO:0003674	molecular_function	No
GO:0071704	organic substance metabolic process	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
Yes	1 - 29	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	7	26	19

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g4054.t1 MITVRPTGGALLWLLLISFCFIFTSANAQDCSALNTCATGCCNKGGYCGIGDDYCGSDCVANCDYEPECSVSKPC ASGCCNSYGYCGLGPDFCADKVCVGNCDSKAECDPGKYGDYAESSKCPLNVCCSKFGFCGTTEEFCGKTKVKRPS CDKDGSLNRVVGYYEGWSPSRRCNTFYPEQIPVGIYIHLNYAFASIDPDTFEIVAATESEKKLMTRLTDLKKVDP DLKVFIAVGGWTFNDPGATQTLFSDLAASESNQKKFFKSLQSFMSIYDFDGIDLDWEYPVADDRGGQKKDFDNFP KFLANLKKSLKSTGGRDGVSITLPASYWYLQHFDIANLQKHVDFFNIMTYDMHGKWDLGSEWVSPMLDSHTNLTE ITNALDLLWRNDIKSDKVVLGLAFYARVFTAADPSCMEPGCLFVSGGNAGKCSQEVGILLNSEIMDIMDKQSLQS TLDKEAAVKILKFDDNQWLTYENSDTFKLKADFARSQCLGGVMVWAVSHDLPQASMEVKKTHPQCKWTNCFDDCP SGWSRVRRTDDGAREGEHMWDSTACSFGQHTFCCPPDAELPKCGWYTHNNGKCNSECPSGYTEIGSNIQYCSNDF NDYQAACCTTETPSMKLYSKCDWAGKPRKCDEECPSGKSEVALSTTGSGGVYCDVTSFKYTMNGQEGTSWEERSY CCSEEDDVEWSKCEWRDDIGLMLDKSYVDGYCLPGCPDEYVRVAIDQHGGGCKGDGGRAKCCLPKYSTVSKRSYT TREQSLDDLVKGFMDDPSCGADDYNLKRDLAGFEYSVGNTSLSDLSGTRTPTTLQRRSTTKQLDAIYTVAYALAV QFTVNAAYEEIWKKRVLPSYPHLTVKAIRNYLTTSEDWAEGGISYKLEKVLCAPSIFDSKFAERSIVSCACETSD CCDANDPDSCSDLDGDDDDSTALSKRVLDKRASRTFDVDLSDGGAHATITSWTYIVRGNIRGNNPILDEGYTYDD AEDCLNTQIALMSVSMANIGRYQVEHVVELNTVAFFLRDAANGVLRSGGVMRLGRISVTFVRQALMAPVLTNPPV MTGADQSLTPMTRIMHALGSLNNQADFNLLLNRLNNLKSRLWLSKTLILDEKMEKAISADDPNRALIHLREPLTI ISYLNHLRIQPDMIDTFNTIHVEFGRADTYWVNAGHPNPQSQARWDEWVPDLLDSATQNVRTFVENWGDQMYRFW AVRTGDNVAQTLEIIMTLRRQAKTARINPNGLD*
Coding	>Pro_DTO377G3_2|g4054.t1 ATGATCACCGTACGCCCAACTGGAGGAGCCCTCCTTTGGCTCCTTTTGATCTCCTTCTGCTTTATATTTACCAGT GCCAATGCACAAGATTGCAGTGCTTTGAACACATGCGCTACTGGATGCTGCAACAAAGGCGGATACTGCGGAATC GGTGATGATTACTGCGGTTCCGACTGCGTTGCGAATTGTGATTACGAGCCAGAATGCAGTGTCTCGAAGCCCTGT GCAAGTGGATGTTGCAACAGCTATGGCTATTGTGGTCTGGGACCAGACTTTTGTGCCGATAAGGTTTGCGTGGGA AACTGCGACAGCAAGGCAGAGTGCGATCCCGGCAAATATGGTGACTATGCGGAATCTTCCAAATGTCCATTGAAT GTCTGCTGCTCGAAGTTCGGCTTCTGCGGCACTACCGAAGAATTTTGTGGCAAGACAAAAGTCAAGCGCCCTTCC TGTGACAAAGATGGATCTCTCAATCGAGTCGTAGGGTACTACGAGGGTTGGAGTCCTTCACGTCGCTGTAATACG TTCTACCCCGAACAAATCCCTGTGGGCATCTATATACACTTGAATTATGCTTTCGCGTCGATCGATCCAGATACA TTCGAGATCGTCGCGGCCACCGAGAGCGAGAAAAAGCTGATGACGCGCTTGACGGATCTTAAGAAGGTCGATCCC GATCTCAAAGTCTTCATTGCCGTTGGTGGCTGGACTTTCAATGATCCTGGAGCCACCCAAACTCTGTTCTCGGAT CTCGCTGCGTCGGAAAGCAATCAGAAGAAGTTCTTCAAGTCCCTCCAGAGTTTCATGTCTATATACGACTTTGAT GGGATTGATCTTGACTGGGAGTATCCCGTGGCGGATGACCGTGGCGGTCAAAAGAAAGATTTCGACAACTTCCCC AAGTTCTTGGCCAATTTGAAGAAATCCCTTAAGTCTACTGGTGGCCGCGATGGAGTCAGCATTACACTGCCCGCT TCTTATTGGTATCTTCAACATTTTGATATCGCAAACCTACAAAAACACGTCGACTTCTTCAACATCATGACCTAT GATATGCATGGAAAATGGGACTTGGGCAGTGAATGGGTTTCCCCTATGCTCGACTCTCATACCAACCTAACAGAG ATTACCAATGCTCTCGATTTGCTCTGGCGAAACGACATCAAGTCTGATAAGGTCGTCCTGGGTCTTGCATTCTAC GCTCGAGTATTCACTGCTGCTGACCCGAGCTGCATGGAGCCTGGTTGTTTGTTTGTTTCCGGTGGAAACGCTGGG AAATGCAGTCAAGAAGTTGGCATCTTACTGAATTCTGAAATTATGGACATCATGGATAAGCAGTCCCTACAGTCC ACGCTGGATAAGGAGGCTGCCGTGAAGATTCTCAAATTTGACGACAACCAGTGGCTTACCTACGAAAATTCAGAC ACATTTAAGCTGAAAGCCGACTTTGCCCGAAGCCAATGCCTTGGTGGTGTGATGGTGTGGGCGGTTTCCCATGAT TTACCCCAAGCGTCAATGGAGGTCAAAAAGACCCATCCGCAGTGCAAGTGGACGAATTGCTTCGACGATTGCCCT AGTGGATGGTCGCGGGTTCGCCGTACAGATGACGGTGCCCGTGAAGGCGAGCACATGTGGGATTCTACCGCATGT AGTTTTGGACAGCATACGTTCTGCTGCCCTCCTGATGCCGAACTTCCCAAATGTGGATGGTATACCCATAACAAT GGTAAATGCAATTCGGAGTGTCCTTCTGGCTACACTGAGATTGGATCCAACATACAATACTGTTCTAACGACTTT AACGACTACCAAGCTGCTTGTTGTACAACTGAAACTCCCAGTATGAAACTTTACTCCAAGTGTGACTGGGCGGGA AAACCACGGAAATGCGACGAGGAATGCCCTAGTGGCAAGTCCGAGGTGGCTCTGTCAACTACCGGCAGTGGTGGT GTATACTGCGACGTTACTTCTTTCAAATACACAATGAACGGCCAAGAGGGCACAAGTTGGGAGGAACGCAGCTAC TGCTGTAGTGAGGAAGACGATGTTGAATGGAGTAAATGCGAATGGCGTGATGACATTGGCCTGATGCTCGACAAA AGCTATGTTGACGGTTACTGTCTCCCCGGCTGTCCGGATGAATACGTGCGTGTCGCTATTGATCAACACGGTGGT GGTTGCAAAGGCGACGGTGGCCGAGCCAAATGCTGCTTGCCAAAATATTCAACAGTCAGCAAGAGATCATACACC ACGCGGGAACAGAGTCTTGATGACTTGGTTAAAGGGTTCATGGATGATCCGAGTTGTGGAGCGGACGATTACAAC TTGAAGAGGGATCTCGCGGGCTTTGAATATTCTGTGGGAAATACCTCTTTGTCCGATCTGTCTGGTACTCGAACT CCAACAACACTTCAACGCCGCTCAACAACCAAACAGCTAGATGCTATCTATACTGTTGCATACGCCCTTGCTGTG CAGTTTACAGTTAATGCAGCCTACGAAGAGATCTGGAAAAAACGTGTGCTGCCATCATACCCACATCTTACAGTC AAGGCTATTCGCAATTACCTGACTACGTCTGAGGACTGGGCTGAAGGAGGTATAAGTTATAAACTAGAGAAGGTT CTTTGCGCCCCAAGCATCTTCGACAGCAAGTTTGCAGAAAGAAGCATTGTCTCCTGCGCATGCGAAACAAGCGAT TGCTGCGATGCAAACGATCCGGATTCCTGTTCGGATCTTGACGGTGATGATGATGATTCTACTGCTCTTAGCAAA AGAGTTTTAGATAAGAGAGCCTCGCGAACGTTCGATGTCGATTTATCAGACGGTGGAGCGCATGCTACGATCACT TCTTGGACGTATATCGTGCGTGGCAACATTCGAGGAAATAATCCCATCTTGGATGAAGGTTATACCTACGATGAC GCTGAGGACTGCCTCAATACTCAAATCGCTTTGATGTCAGTTTCGATGGCGAATATCGGAAGATATCAGGTCGAA CATGTCGTTGAGTTGAACACCGTTGCCTTTTTCCTGAGAGATGCAGCCAATGGGGTCCTCAGGTCTGGTGGTGTG ATGAGACTCGGTCGAATTTCAGTGACCTTCGTTAGACAGGCTCTGATGGCGCCAGTTCTTACCAACCCACCAGTA ATGACTGGTGCCGACCAATCCTTGACTCCCATGACCCGGATTATGCATGCTTTGGGTAGCCTGAACAACCAAGCT GATTTCAACCTTTTGCTTAATCGTTTGAACAACTTAAAATCCAGGCTCTGGCTTTCAAAAACACTCATCCTTGAT GAAAAAATGGAGAAAGCAATCTCAGCCGATGACCCGAATCGCGCATTGATACATCTCCGCGAGCCCCTCACTATT ATTTCCTATCTCAACCATCTCAGAATCCAGCCTGACATGATCGACACTTTTAACACAATTCACGTAGAATTCGGT CGAGCAGATACGTACTGGGTGAATGCTGGACATCCAAACCCGCAGTCGCAAGCCAGATGGGATGAATGGGTTCCT GACTTATTAGATAGTGCCACTCAGAATGTTCGCACGTTTGTTGAAAATTGGGGGGATCAGATGTATAGGTTTTGG GCAGTCCGGACTGGTGATAACGTTGCGCAAACGCTCGAGATCATTATGACTTTGCGAAGACAGGCTAAAACTGCG AGGATTAATCCGAATGGCCTGGATTGA
Transcript	>Pro_DTO377G3_2|g4054.t1 ATGATCACCGTACGCCCAACTGGAGGAGCCCTCCTTTGGCTCCTTTTGATCTCCTTCTGCTTTATATTTACCAGT GCCAATGCACAAGATTGCAGTGCTTTGAACACATGCGCTACTGGATGCTGCAACAAAGGCGGATACTGCGGAATC GGTGATGATTACTGCGGTTCCGACTGCGTTGCGAATTGTGATTACGAGCCAGAATGCAGTGTCTCGAAGCCCTGT GCAAGTGGATGTTGCAACAGCTATGGCTATTGTGGTCTGGGACCAGACTTTTGTGCCGATAAGGTTTGCGTGGGA AACTGCGACAGCAAGGCAGAGTGCGATCCCGGCAAATATGGTGACTATGCGGAATCTTCCAAATGTCCATTGAAT GTCTGCTGCTCGAAGTTCGGCTTCTGCGGCACTACCGAAGAATTTTGTGGCAAGACAAAAGTCAAGCGCCCTTCC TGTGACAAAGATGGATCTCTCAATCGAGTCGTAGGGTACTACGAGGGTTGGAGTCCTTCACGTCGCTGTAATACG TTCTACCCCGAACAAATCCCTGTGGGCATCTATATACACTTGAATTATGCTTTCGCGTCGATCGATCCAGATACA TTCGAGATCGTCGCGGCCACCGAGAGCGAGAAAAAGCTGATGACGCGCTTGACGGATCTTAAGAAGGTCGATCCC GATCTCAAAGTCTTCATTGCCGTTGGTGGCTGGACTTTCAATGATCCTGGAGCCACCCAAACTCTGTTCTCGGAT CTCGCTGCGTCGGAAAGCAATCAGAAGAAGTTCTTCAAGTCCCTCCAGAGTTTCATGTCTATATACGACTTTGAT GGGATTGATCTTGACTGGGAGTATCCCGTGGCGGATGACCGTGGCGGTCAAAAGAAAGATTTCGACAACTTCCCC AAGTTCTTGGCCAATTTGAAGAAATCCCTTAAGTCTACTGGTGGCCGCGATGGAGTCAGCATTACACTGCCCGCT TCTTATTGGTATCTTCAACATTTTGATATCGCAAACCTACAAAAACACGTCGACTTCTTCAACATCATGACCTAT GATATGCATGGAAAATGGGACTTGGGCAGTGAATGGGTTTCCCCTATGCTCGACTCTCATACCAACCTAACAGAG ATTACCAATGCTCTCGATTTGCTCTGGCGAAACGACATCAAGTCTGATAAGGTCGTCCTGGGTCTTGCATTCTAC GCTCGAGTATTCACTGCTGCTGACCCGAGCTGCATGGAGCCTGGTTGTTTGTTTGTTTCCGGTGGAAACGCTGGG AAATGCAGTCAAGAAGTTGGCATCTTACTGAATTCTGAAATTATGGACATCATGGATAAGCAGTCCCTACAGTCC ACGCTGGATAAGGAGGCTGCCGTGAAGATTCTCAAATTTGACGACAACCAGTGGCTTACCTACGAAAATTCAGAC ACATTTAAGCTGAAAGCCGACTTTGCCCGAAGCCAATGCCTTGGTGGTGTGATGGTGTGGGCGGTTTCCCATGAT TTACCCCAAGCGTCAATGGAGGTCAAAAAGACCCATCCGCAGTGCAAGTGGACGAATTGCTTCGACGATTGCCCT AGTGGATGGTCGCGGGTTCGCCGTACAGATGACGGTGCCCGTGAAGGCGAGCACATGTGGGATTCTACCGCATGT AGTTTTGGACAGCATACGTTCTGCTGCCCTCCTGATGCCGAACTTCCCAAATGTGGATGGTATACCCATAACAAT GGTAAATGCAATTCGGAGTGTCCTTCTGGCTACACTGAGATTGGATCCAACATACAATACTGTTCTAACGACTTT AACGACTACCAAGCTGCTTGTTGTACAACTGAAACTCCCAGTATGAAACTTTACTCCAAGTGTGACTGGGCGGGA AAACCACGGAAATGCGACGAGGAATGCCCTAGTGGCAAGTCCGAGGTGGCTCTGTCAACTACCGGCAGTGGTGGT GTATACTGCGACGTTACTTCTTTCAAATACACAATGAACGGCCAAGAGGGCACAAGTTGGGAGGAACGCAGCTAC TGCTGTAGTGAGGAAGACGATGTTGAATGGAGTAAATGCGAATGGCGTGATGACATTGGCCTGATGCTCGACAAA AGCTATGTTGACGGTTACTGTCTCCCCGGCTGTCCGGATGAATACGTGCGTGTCGCTATTGATCAACACGGTGGT GGTTGCAAAGGCGACGGTGGCCGAGCCAAATGCTGCTTGCCAAAATATTCAACAGTCAGCAAGAGATCATACACC ACGCGGGAACAGAGTCTTGATGACTTGGTTAAAGGGTTCATGGATGATCCGAGTTGTGGAGCGGACGATTACAAC TTGAAGAGGGATCTCGCGGGCTTTGAATATTCTGTGGGAAATACCTCTTTGTCCGATCTGTCTGGTACTCGAACT CCAACAACACTTCAACGCCGCTCAACAACCAAACAGCTAGATGCTATCTATACTGTTGCATACGCCCTTGCTGTG CAGTTTACAGTTAATGCAGCCTACGAAGAGATCTGGAAAAAACGTGTGCTGCCATCATACCCACATCTTACAGTC AAGGCTATTCGCAATTACCTGACTACGTCTGAGGACTGGGCTGAAGGAGGTATAAGTTATAAACTAGAGAAGGTT CTTTGCGCCCCAAGCATCTTCGACAGCAAGTTTGCAGAAAGAAGCATTGTCTCCTGCGCATGCGAAACAAGCGAT TGCTGCGATGCAAACGATCCGGATTCCTGTTCGGATCTTGACGGTGATGATGATGATTCTACTGCTCTTAGCAAA AGAGTTTTAGATAAGAGAGCCTCGCGAACGTTCGATGTCGATTTATCAGACGGTGGAGCGCATGCTACGATCACT TCTTGGACGTATATCGTGCGTGGCAACATTCGAGGAAATAATCCCATCTTGGATGAAGGTTATACCTACGATGAC GCTGAGGACTGCCTCAATACTCAAATCGCTTTGATGTCAGTTTCGATGGCGAATATCGGAAGATATCAGGTCGAA CATGTCGTTGAGTTGAACACCGTTGCCTTTTTCCTGAGAGATGCAGCCAATGGGGTCCTCAGGTCTGGTGGTGTG ATGAGACTCGGTCGAATTTCAGTGACCTTCGTTAGACAGGCTCTGATGGCGCCAGTTCTTACCAACCCACCAGTA ATGACTGGTGCCGACCAATCCTTGACTCCCATGACCCGGATTATGCATGCTTTGGGTAGCCTGAACAACCAAGCT GATTTCAACCTTTTGCTTAATCGTTTGAACAACTTAAAATCCAGGCTCTGGCTTTCAAAAACACTCATCCTTGAT GAAAAAATGGAGAAAGCAATCTCAGCCGATGACCCGAATCGCGCATTGATACATCTCCGCGAGCCCCTCACTATT ATTTCCTATCTCAACCATCTCAGAATCCAGCCTGACATGATCGACACTTTTAACACAATTCACGTAGAATTCGGT CGAGCAGATACGTACTGGGTGAATGCTGGACATCCAAACCCGCAGTCGCAAGCCAGATGGGATGAATGGGTTCCT GACTTATTAGATAGTGCCACTCAGAATGTTCGCACGTTTGTTGAAAATTGGGGGGATCAGATGTATAGGTTTTGG GCAGTCCGGACTGGTGATAACGTTGCGCAAACGCTCGAGATCATTATGACTTTGCGAAGACAGGCTAAAACTGCG AGGATTAATCCGAATGGCCTGGATTGA
Gene	>Pro_DTO377G3_2|g4054.t1 ATGATCACCGTACGCCCAACTGGAGGAGCCCTCCTTTGGCTCCTTTTGATCTCCTTCTGCTTTATATTTACCAGT GCCAATGCACAAGATTGCAGTGCTTTGAACACATGCGCTACTGGATGCTGCAACAAAGGCGGATACTGCGGAATC GGTGATGATTACTGCGGTTCCGACTGCGTTGCGAATTGTGATTACGAGCCAGAATGCAGTGTCTCGAAGCCCTGT GCAAGTGGATGTTGCAACAGCTATGGCTATTGTGGTCTGGGACCAGACTGTGAGTTTCTCAATCCTCTAAAACCT AGTTACCGTGTCTTTCTAGAGCATATTTCTGACATGAAATTTCAGTTTGTGCCGATAAGGTTTGCGTGGGAAACT GCGACAGCAAGGCAGAGTGCGATCCCGGCAAATATGGTGACTATGCGGAATCTTCCAAATGTCCATTGAATGTCT GCTGCTCGAAGTTCGGCTTCTGCGGCACTACCGAAGAATTTTGTGGCAAGACAAAAGTCAAGCGCCCTTCCTGTG ACAAAGATGGATCTCTCAATCGAGTCGTAGGGTACTACGAGGGTTGGAGTCCTTCACGTCGCTGTAATACGTTCT ACCCCGAACAAATCCCTGTGGGCATCTATATACACTTGAATTATGCTTTCGCGTCGATCGATCCAGATACATTCG AGATCGTCGCGGCCACCGAGAGCGAGAAAAAGCTGATGACGCGCTTGACGGATCTTAAGAAGGTCGATCCCGATC TCAAAGTCTTCATTGCCGTTGGTGGCTGGACTTTCAATGATCCTGGAGCCACCCAAACTCTGTTCTCGGATCTCG CTGCGTCGGAAAGCAATCAGAAGAAGTTCTTCAAGTCCCTCCAGAGTTTCATGTCTATATACGACTTTGATGGGA TTGATCTTGACTGGGAGTATCCCGTGGCGGATGACCGTGGCGGTCAAAAGAAAGATTTCGACAACTTCCCCAAGT TCTTGGCCAATTTGAAGAAATCCCTTAAGTCTACTGGTGGCCGCGATGGAGTCAGCATTACACTGCCCGCTTCTT ATTGGTATCTTCAACATTTTGATATCGCAAACCTACAAAAACACGTCGACTTCTTCAACATCATGACCTATGATA TGCATGGAAAATGGGACTTGGGCAGTGAATGGGTTTCCCCTATGCTCGACTCTCATACCAACCTAACAGAGATTA CCAATGCTCTCGATTTGCTCTGGCGAAACGACATCAAGTCTGATAAGGTCGTCCTGGGTCTTGCATTCTACGCTC GAGTATTCACTGCTGCTGACCCGAGCTGCATGGAGCCTGGTTGTTTGTTTGTTTCCGGTGGAAACGCTGGGAAAT GCAGTCAAGAAGTTGGCATCTTACTGAATTCTGAAATTATGGACATCATGGATAAGCAGTCCCTACAGTCCACGC TGGATAAGGAGGCTGCCGTGAAGATTCTCAAATTTGACGACAACCAGTGGCTTACCTACGAAAATTCAGACACAT TTAAGCTGAAAGCCGACTTTGCCCGAAGCCAATGCCTTGGTGGTGTGATGGTGTGGGCGGTTTCCCATGATTTAC CCCAAGGTAACTTTTCCCGAGCCCTTGGAGATGCCGTGGGCAGAAGTGAAGTCCCTTGTCAACAGCGGTGAATTA GCGTCAATGGAGGTCAAAAAGACCCATCCGCAGTGCAAGTGGACGAATTGCTTCGACGATTGCCCTAGTGGATGG TCGCGGGTTCGCCGTACAGATGACGGTGCCCGTGAAGGCGAGCACATGTGGGATTCTACCGCATGTAGTTTTGGA CAGCATACGTTCTGCTGCCCTCCTGATGCCGAACTTCCCAAATGTGGATGGTATACCCATAACAATGGTAAATGC AATTCGGAGTGTCCTTCTGGCTACACTGAGATTGGATCCAACATACAATACTGTTCTAACGACTTTAACGACTAC CAAGCTGCTTGTTGTACAACTGAAACTCCCAGTATGAAACTTTACTCCAAGTGTGACTGGGCGGGAAAACCACGG AAATGCGACGAGGAATGCCCTAGTGGCAAGTCCGAGGTGGCTCTGTCAACTACCGGCAGTGGTGGTGTATACTGC GACGTTACTTCTTTCAAATACACAATGAACGGCCAAGAGGGCACAAGTTGGGAGGAACGCAGCTACTGCTGTAGT GAGGAAGACGATGTTGAATGGAGTAAATGCGAATGGCGTGATGACATTGGCCTGATGCTCGACAAAAGCTATGTT GACGGTTACTGTCTCCCCGGCTGTCCGGATGAATACGTGCGTGTCGCTATTGATCAACACGGTGGTGGTTGCAAA GGCGACGGTGGCCGAGCCAAATGCTGCTTGCCAAAATATTCAACAGTCAGCAAGAGATCATACACCACGCGGGAA CAGAGTCTTGATGACTTGGTTAAAGGGTTCATGGATGATCCGAGTTGTGGAGCGGACGATTACAACTTGAAGAGG GATCTCGCGGGCTTTGAATATTCTGTGGGAAATACCTCTTTGTCCGATCTGTCTGGTACTCGAACTCCAACAACA CTTCAACGCCGCTCAACAACCAAACAGCTAGATGCTATCTATACTGTTGCATACGCCCTTGCTGTGCAGTTTACA GTTAATGCAGCCTACGAAGAGATCTGGAAAAAACGTGTGCTGCCATCATACCCACATCTTACAGTCAAGGCTATT CGCAATTACCTGACTACGTCTGAGGACTGGGCTGAAGGAGGTATAAGTTATAAACTAGAGAAGGTTCTTTGCGCC CCAAGCATCTTCGACAGCAAGTTTGCAGAAAGAAGCATTGTCTCCTGCGCATGCGAAACAAGCGATTGCTGCGAT GCAAACGATCCGGATTCCTGTTCGGATCTTGACGGTGATGATGATGATTCTACTGCTCTTAGCAAAAGAGTTTTA GATAAGAGAGCCTCGCGAACGTTCGATGTCGATTTATCAGACGGTGGAGCGCATGCTACGATCACTTCTTGGACG GTATTAATCTTCAAGTCCCAATCAACGTATTTTTAGTGCTAATCAGACGATCAGTATATCGTGCGTGGCAACATT CGAGGAAATAATCCCATCTTGGATGAAGGTTATACCTACGATGACGCTGAGGACTGCCTCAATACTCAAATCGCT TTGATGTCAGTTTCGATGGCGAATATCGGAAGATATCAGGGTACGTTCTTGGTGACCTTGTTTACCCTGAAAGTT TACTCAATTTACTAATTAATCAAGTCGAACATGTCGTTGAGTTGAACACCGTTGCCTTTTTCCTGAGAGATGCAG CCAATGGGGTCCTCAGGTCTGGTGGTGTGATGAGACTCGGTCGAATTTCAGTGACCTTCGTTAGACAGGCTCTGA TGGCGCCAGTTCTTACCAACCCACCAGTAATGACTGGTGCCGACCAATCCTTGACTCCCATGACCCGGATTATGC ATGCTTTGGGTAGCCTGAACAACCAAGCTGATTTCAACCTTTTGCTTAATCGTTTGAACAACTTAAAATCCAGGG TATTTGATCATTTACAATTTTTTTTTTCTGGAGATGACCAAGTTACTTATCATTTCTTTTCTCTAGCTCTGGCTT TCAAAAACACTCATCCTTGATGAAAAAATGGAGAAAGCAATCTCAGCCGATGACCCGAATCGCGCATTGATACAT CTCCGCGAGCCCCTCACTATTATTTCCTATCTCAACCATCTCAGAATCCAGCCTGACATGATCGACACTTTTAAC ACAATTCACGTAGAATTCGGTCGAGCAGATACGTACTGGGTGAATGCTGGACATCCAAACCCGCAGTCGCAAGCC AGATGGGATGAATGGGTTCCTGACTTATTAGATAGTGCCACTCAGAATGTTCGCACGTTTGTTGAAAATTGGGGG GATCAGATGTATAGGTTTTGGGCAGTCCGGACTGGTGATAACGTTGCGCAAACGCTCGAGATCATTATGACTTTG CGAAGACAGGCTAAAACTGCGAGGATTAATCCGAATGGCCTGGATTGA