Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g3865.t1
Gene name
Location	scaffold_07:122512..126619
Strand	-
Gene length (bp)	4107
Transcript length (bp)	3429
Coding sequence length (bp)	3429
Protein length (aa)	1143

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00704	Glyco_hydro_18	Glycosyl hydrolases family 18	1.2E-72	159	508
PF00187	Chitin_bind_1	Chitin recognition protein	1.1E-11	101	140

GO

GO Term	Description	Terminal node
GO:0005975	carbohydrate metabolic process	Yes
GO:0008061	chitin binding	Yes
GO:0097367	carbohydrate derivative binding	No
GO:0008150	biological_process	No
GO:0044238	primary metabolic process	No
GO:0005488	binding	No
GO:0008152	metabolic process	No
GO:0003674	molecular_function	No
GO:0071704	organic substance metabolic process	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
Yes	1 - 33	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	12	34	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g3865.t1 MEALIARPPTRLFQAALTVFLLVCVFAAVVDASHGHSLHERHHKWHSQAKPAANLLRRDAYACDANTPCSNGACC GAGGYCGYEPTYCGTGCVSNCDATAECGQYASTVNQTCPLNVCCSQYEFCGTTEDFCDSDCQSNCVLNTKPPAGA ASLSVLENKVIGYYESWMARKKCHKVAPTDLPLDALTHLNFAFASIDPDSYTIVTMDSDTPSSLFKDATNVKSIK SDIKVFVSVGGWTFSDNGTATQPLYGEIAASATKRQTFADNVVHFLKQYGFDGLDIDWEYPGAGDRGGSAEDTAN YVLLLQTLRKTFDASGNDFGLTFTAPSSYWYLRWFDLPSMVKYADWINLMTYDLHGVWDSTDPIGSIVQAHTNLT EIKQSAELFWRVDIPPEKLVMGFGFYGRSFTLADKSCTKPGCPFKGASSPGPCSDTGGILAYYEIQAILDGTSSS SKRSTITPIHDKNDAVNYFTFDDDQWVSYDDETTFAQKVTWANEVGLGGAMIWASDLDDDKYTAHAGLTNKPIMT NPTLKTIDKALSDPKSVIQDLASFNGQNCFKYEGKCVNLNDNNAMADACGSGYTVVGWDDAGCGKSNCHCGKPIC CPTGSAPKNCNWRGDNTGDAGVSSDCNAQCKSGEINIAGIRSSWGGGFTNDGNTDKCGRGYKVFCCPDPEYKEVI DGCAYAGCGKDCPSGSTEMFNKIDTCGYKGQKYCCTSPADLSDCHWVGGSSGQDCANAKCASTELAVDRASYGDS SSLCDWSRQKVACCTVKKAAREPAKCAADLCTLFPGWCPSNSDETSVSYRKRGELNVLEKRGAREKYTLILAGVT IEVLAAAYPSIGDLFTIARAAQVQRWAFWKNKGYCNSRVLSVLSLPTGEVAKALYEGLNSEHVIDRQVIKKFIEA VISGTLTSGAQPDGLLPMSATWWATKWREANAALAGLPAVGSDNGAQPSSPNDRIMEAFGSTFNPYPLLATDAGI NGAKGKLMGLKAPFSIKNIEKLAKAAVKADTDEAVQEVLTALQSVFGMFEYFADYRVSKTYNWVLQSVGLQMAQV EYATGVQDLQKWWWAWAPDYFQTVEDYSQGWAVEAIRAVAGAYAAARADGRNLKTNDAVAAVLSEFESKIQKMSM PKITATETTISDLDSLD*
Coding	>Pro_DTO377G3_2|g3865.t1 ATGGAGGCTCTTATTGCGAGGCCACCTACAAGGCTGTTTCAAGCTGCTCTGACGGTGTTCTTACTCGTCTGTGTC TTTGCCGCCGTTGTAGATGCCTCCCATGGACATTCGCTCCATGAGAGACATCATAAATGGCATTCACAGGCAAAG CCTGCGGCTAACCTCCTCCGACGCGATGCTTATGCGTGTGACGCCAACACCCCATGCAGCAACGGCGCATGCTGC GGAGCTGGTGGCTACTGTGGTTATGAACCTACGTACTGTGGCACTGGCTGCGTGTCGAACTGCGATGCCACCGCC GAGTGTGGTCAGTATGCTAGTACAGTCAACCAAACTTGCCCTCTGAATGTGTGCTGCAGTCAGTATGAATTTTGT GGTACCACGGAAGACTTTTGTGACTCGGACTGCCAGAGCAACTGTGTTCTCAATACTAAGCCCCCAGCTGGTGCT GCATCGTTGAGCGTTCTTGAAAATAAAGTCATTGGCTACTATGAATCCTGGATGGCTCGCAAAAAATGTCACAAA GTGGCTCCTACCGACCTGCCCTTGGATGCCCTCACACATCTCAACTTTGCATTTGCGTCCATCGATCCTGACTCG TACACGATCGTGACCATGGACAGTGACACCCCGTCTAGTCTGTTCAAAGACGCAACGAATGTCAAATCCATCAAA TCTGACATAAAGGTCTTCGTCAGTGTGGGCGGCTGGACATTCTCCGATAACGGCACGGCCACCCAGCCGCTGTAC GGCGAGATTGCTGCGTCGGCCACCAAGAGACAGACATTTGCTGACAACGTCGTCCACTTCCTTAAGCAGTATGGA TTTGACGGCTTGGACATTGACTGGGAATACCCAGGCGCCGGTGACCGAGGTGGAAGTGCCGAAGACACAGCCAAC TATGTGCTCCTGCTACAGACGCTGCGCAAGACCTTCGACGCTAGCGGTAACGACTTTGGTCTGACATTTACGGCC CCGTCCTCCTACTGGTATCTGCGTTGGTTTGACTTGCCAAGCATGGTCAAGTACGCTGACTGGATCAATCTGATG ACCTATGATCTGCACGGGGTCTGGGATAGCACCGATCCCATTGGCAGTATTGTGCAAGCTCATACAAACCTGACA GAGATTAAGCAGTCTGCGGAGCTATTCTGGCGTGTAGATATCCCCCCAGAGAAGCTCGTCATGGGCTTTGGCTTC TATGGACGGTCTTTCACGCTTGCGGACAAGTCGTGCACGAAACCTGGTTGTCCATTCAAGGGTGCCTCAAGTCCA GGCCCCTGCTCCGATACTGGTGGAATCTTGGCTTACTATGAGATCCAAGCGATCTTAGATGGCACGAGTAGTTCC TCTAAGCGATCAACCATCACGCCAATTCATGACAAGAATGATGCAGTCAATTATTTCACATTCGACGACGATCAG TGGGTTTCTTATGATGATGAGACAACTTTTGCCCAAAAGGTGACGTGGGCCAACGAGGTTGGTCTTGGAGGCGCC ATGATCTGGGCTTCAGATCTGGACGACGACAAATACACGGCCCACGCAGGTCTCACCAATAAACCTATCATGACG AACCCGACCTTGAAGACCATAGACAAAGCCTTGTCCGACCCCAAGTCCGTCATTCAAGACCTAGCCAGCTTCAAC GGCCAGAACTGCTTCAAATACGAAGGTAAATGCGTCAACCTTAACGACAACAATGCCATGGCGGATGCTTGTGGC TCTGGATATACCGTTGTCGGGTGGGATGACGCTGGATGCGGCAAATCGAATTGTCACTGTGGAAAGCCCATCTGC TGTCCGACGGGCTCCGCTCCAAAGAATTGCAACTGGCGTGGCGACAACACCGGTGATGCTGGCGTCTCATCAGAC TGTAATGCGCAATGCAAATCGGGAGAAATCAACATCGCCGGCATTCGATCGTCATGGGGAGGTGGTTTTACCAAT GATGGTAACACTGACAAGTGTGGCCGCGGATACAAGGTCTTTTGCTGCCCTGATCCTGAGTATAAAGAGGTCATT GACGGATGTGCCTACGCGGGCTGCGGCAAAGATTGCCCTAGTGGAAGCACAGAGATGTTTAACAAGATCGACACT TGCGGGTACAAGGGTCAAAAATACTGCTGTACGTCTCCAGCCGACTTGTCTGACTGCCATTGGGTCGGAGGAAGT TCTGGCCAGGACTGCGCAAATGCCAAGTGCGCCTCCACGGAGCTGGCAGTTGACCGCGCTAGTTACGGTGACTCG AGCTCCTTATGCGACTGGAGCCGCCAGAAGGTCGCCTGCTGCACAGTCAAGAAGGCTGCACGGGAGCCAGCCAAG TGCGCTGCCGATCTGTGTACGCTGTTTCCCGGCTGGTGTCCAAGTAATAGCGATGAGACTTCTGTCAGCTACCGC AAGCGAGGTGAGCTCAACGTACTGGAGAAGCGTGGTGCCCGAGAGAAATATACTCTTATACTGGCCGGTGTGACT ATCGAGGTCCTCGCCGCCGCATACCCGTCAATTGGAGATCTCTTCACGATCGCCCGAGCCGCTCAAGTTCAACGA TGGGCTTTTTGGAAGAACAAAGGCTACTGCAATAGCAGAGTTCTATCCGTACTGTCTCTTCCGACTGGCGAGGTC GCCAAAGCCCTGTACGAAGGCTTGAACTCGGAGCACGTCATCGATAGGCAGGTCATTAAAAAGTTCATTGAGGCT GTGATATCGGGGACTTTGACATCCGGTGCCCAGCCAGATGGTCTCTTGCCCATGTCGGCCACCTGGTGGGCAACT AAGTGGAGGGAGGCCAATGCGGCCCTTGCAGGTCTTCCTGCGGTAGGCAGTGATAACGGAGCCCAGCCATCGAGT CCTAATGACCGAATCATGGAAGCTTTCGGGTCGACATTCAACCCGTACCCACTGCTGGCCACTGACGCTGGAATC AATGGAGCTAAGGGCAAACTCATGGGTCTCAAAGCTCCTTTTAGCATCAAAAATATAGAAAAATTGGCAAAGGCC GCTGTCAAGGCCGATACTGACGAGGCTGTGCAGGAGGTTCTAACAGCCCTTCAGAGCGTGTTTGGCATGTTCGAG TACTTCGCCGACTATCGTGTCTCCAAGACGTATAACTGGGTTCTCCAAAGCGTCGGTCTGCAGATGGCCCAAGTC GAGTATGCTACCGGCGTTCAAGATCTGCAAAAATGGTGGTGGGCGTGGGCACCAGACTACTTCCAGACGGTAGAG GACTATTCCCAAGGTTGGGCCGTCGAAGCTATTCGGGCCGTTGCAGGAGCGTACGCCGCGGCTCGTGCCGATGGG CGGAATCTGAAGACGAATGATGCCGTCGCGGCGGTGCTCAGCGAATTCGAGAGCAAGATCCAGAAGATGAGCATG CCGAAGATCACGGCGACAGAGACTACCATCTCCGACTTGGACTCTCTAGACTAG
Transcript	>Pro_DTO377G3_2|g3865.t1 ATGGAGGCTCTTATTGCGAGGCCACCTACAAGGCTGTTTCAAGCTGCTCTGACGGTGTTCTTACTCGTCTGTGTC TTTGCCGCCGTTGTAGATGCCTCCCATGGACATTCGCTCCATGAGAGACATCATAAATGGCATTCACAGGCAAAG CCTGCGGCTAACCTCCTCCGACGCGATGCTTATGCGTGTGACGCCAACACCCCATGCAGCAACGGCGCATGCTGC GGAGCTGGTGGCTACTGTGGTTATGAACCTACGTACTGTGGCACTGGCTGCGTGTCGAACTGCGATGCCACCGCC GAGTGTGGTCAGTATGCTAGTACAGTCAACCAAACTTGCCCTCTGAATGTGTGCTGCAGTCAGTATGAATTTTGT GGTACCACGGAAGACTTTTGTGACTCGGACTGCCAGAGCAACTGTGTTCTCAATACTAAGCCCCCAGCTGGTGCT GCATCGTTGAGCGTTCTTGAAAATAAAGTCATTGGCTACTATGAATCCTGGATGGCTCGCAAAAAATGTCACAAA GTGGCTCCTACCGACCTGCCCTTGGATGCCCTCACACATCTCAACTTTGCATTTGCGTCCATCGATCCTGACTCG TACACGATCGTGACCATGGACAGTGACACCCCGTCTAGTCTGTTCAAAGACGCAACGAATGTCAAATCCATCAAA TCTGACATAAAGGTCTTCGTCAGTGTGGGCGGCTGGACATTCTCCGATAACGGCACGGCCACCCAGCCGCTGTAC GGCGAGATTGCTGCGTCGGCCACCAAGAGACAGACATTTGCTGACAACGTCGTCCACTTCCTTAAGCAGTATGGA TTTGACGGCTTGGACATTGACTGGGAATACCCAGGCGCCGGTGACCGAGGTGGAAGTGCCGAAGACACAGCCAAC TATGTGCTCCTGCTACAGACGCTGCGCAAGACCTTCGACGCTAGCGGTAACGACTTTGGTCTGACATTTACGGCC CCGTCCTCCTACTGGTATCTGCGTTGGTTTGACTTGCCAAGCATGGTCAAGTACGCTGACTGGATCAATCTGATG ACCTATGATCTGCACGGGGTCTGGGATAGCACCGATCCCATTGGCAGTATTGTGCAAGCTCATACAAACCTGACA GAGATTAAGCAGTCTGCGGAGCTATTCTGGCGTGTAGATATCCCCCCAGAGAAGCTCGTCATGGGCTTTGGCTTC TATGGACGGTCTTTCACGCTTGCGGACAAGTCGTGCACGAAACCTGGTTGTCCATTCAAGGGTGCCTCAAGTCCA GGCCCCTGCTCCGATACTGGTGGAATCTTGGCTTACTATGAGATCCAAGCGATCTTAGATGGCACGAGTAGTTCC TCTAAGCGATCAACCATCACGCCAATTCATGACAAGAATGATGCAGTCAATTATTTCACATTCGACGACGATCAG TGGGTTTCTTATGATGATGAGACAACTTTTGCCCAAAAGGTGACGTGGGCCAACGAGGTTGGTCTTGGAGGCGCC ATGATCTGGGCTTCAGATCTGGACGACGACAAATACACGGCCCACGCAGGTCTCACCAATAAACCTATCATGACG AACCCGACCTTGAAGACCATAGACAAAGCCTTGTCCGACCCCAAGTCCGTCATTCAAGACCTAGCCAGCTTCAAC GGCCAGAACTGCTTCAAATACGAAGGTAAATGCGTCAACCTTAACGACAACAATGCCATGGCGGATGCTTGTGGC TCTGGATATACCGTTGTCGGGTGGGATGACGCTGGATGCGGCAAATCGAATTGTCACTGTGGAAAGCCCATCTGC TGTCCGACGGGCTCCGCTCCAAAGAATTGCAACTGGCGTGGCGACAACACCGGTGATGCTGGCGTCTCATCAGAC TGTAATGCGCAATGCAAATCGGGAGAAATCAACATCGCCGGCATTCGATCGTCATGGGGAGGTGGTTTTACCAAT GATGGTAACACTGACAAGTGTGGCCGCGGATACAAGGTCTTTTGCTGCCCTGATCCTGAGTATAAAGAGGTCATT GACGGATGTGCCTACGCGGGCTGCGGCAAAGATTGCCCTAGTGGAAGCACAGAGATGTTTAACAAGATCGACACT TGCGGGTACAAGGGTCAAAAATACTGCTGTACGTCTCCAGCCGACTTGTCTGACTGCCATTGGGTCGGAGGAAGT TCTGGCCAGGACTGCGCAAATGCCAAGTGCGCCTCCACGGAGCTGGCAGTTGACCGCGCTAGTTACGGTGACTCG AGCTCCTTATGCGACTGGAGCCGCCAGAAGGTCGCCTGCTGCACAGTCAAGAAGGCTGCACGGGAGCCAGCCAAG TGCGCTGCCGATCTGTGTACGCTGTTTCCCGGCTGGTGTCCAAGTAATAGCGATGAGACTTCTGTCAGCTACCGC AAGCGAGGTGAGCTCAACGTACTGGAGAAGCGTGGTGCCCGAGAGAAATATACTCTTATACTGGCCGGTGTGACT ATCGAGGTCCTCGCCGCCGCATACCCGTCAATTGGAGATCTCTTCACGATCGCCCGAGCCGCTCAAGTTCAACGA TGGGCTTTTTGGAAGAACAAAGGCTACTGCAATAGCAGAGTTCTATCCGTACTGTCTCTTCCGACTGGCGAGGTC GCCAAAGCCCTGTACGAAGGCTTGAACTCGGAGCACGTCATCGATAGGCAGGTCATTAAAAAGTTCATTGAGGCT GTGATATCGGGGACTTTGACATCCGGTGCCCAGCCAGATGGTCTCTTGCCCATGTCGGCCACCTGGTGGGCAACT AAGTGGAGGGAGGCCAATGCGGCCCTTGCAGGTCTTCCTGCGGTAGGCAGTGATAACGGAGCCCAGCCATCGAGT CCTAATGACCGAATCATGGAAGCTTTCGGGTCGACATTCAACCCGTACCCACTGCTGGCCACTGACGCTGGAATC AATGGAGCTAAGGGCAAACTCATGGGTCTCAAAGCTCCTTTTAGCATCAAAAATATAGAAAAATTGGCAAAGGCC GCTGTCAAGGCCGATACTGACGAGGCTGTGCAGGAGGTTCTAACAGCCCTTCAGAGCGTGTTTGGCATGTTCGAG TACTTCGCCGACTATCGTGTCTCCAAGACGTATAACTGGGTTCTCCAAAGCGTCGGTCTGCAGATGGCCCAAGTC GAGTATGCTACCGGCGTTCAAGATCTGCAAAAATGGTGGTGGGCGTGGGCACCAGACTACTTCCAGACGGTAGAG GACTATTCCCAAGGTTGGGCCGTCGAAGCTATTCGGGCCGTTGCAGGAGCGTACGCCGCGGCTCGTGCCGATGGG CGGAATCTGAAGACGAATGATGCCGTCGCGGCGGTGCTCAGCGAATTCGAGAGCAAGATCCAGAAGATGAGCATG CCGAAGATCACGGCGACAGAGACTACCATCTCCGACTTGGACTCTCTAGACTAG
Gene	>Pro_DTO377G3_2|g3865.t1 ATGGAGGCTCTTATTGCGAGGCCACCTACAAGGCTGTTTCAAGCTGCTCTGACGGTGTTCTTACTCGTCTGTGTC TTTGCCGCCGTTGTAGATGCCTCCCATGGACATTCGCTCCATGAGAGACATCATAAATGGCATTCACAGGCAAAG CCTGCGGCTAACCTCCTCCGACGCGATGCTTATGCGTGTGACGCCAACACCCCATGCAGCAACGGCGCATGCTGC GGAGCTGGTGGCTACTGTGGTTATGAACCTACGTACTGTGGCACTGGCTGCGTGTCGAACTGCGATGCCACCGCC GAGTGTGGTCAGTATGCTAGTACAGTCAACCAAACTTGCCCTCTGAATGTGTGCTGCAGTCAGTATGAATTTGTC AGTACCTCTAAGATCTGCAACATAACAAGTGAGCCCGAGACTAACTGTAACTAGTGTGGTACCACGGAAGACTTT TGTGACTGTATGTATCCCCATCTGTATACAGCATAGCTACTGGAAGCTAATTATATGATCAGCGGACTGCCAGAG CAACTGTGTTCTCAATACTAAGCCCCCAGCTGGTGCTGCATCGTTGAGCGTTCTTGAAAATAAAGTCATTGGCTA CTATGAATCCTGGATGGCTCGCAAAAAATGTCACAAAGTGGCTCCTACCGACCTGCCCTTGGATGCCCTCACACA GTGAGTCTTGAAAAACATCTCCTCATGCTGAAAAAGCGTGAAATATTGAAACGACAGAAAGAAAACAATCTAACA GAATGATGATAGTCTCAACTTTGCATTTGCGTCCATCGATCCTGACTCGTACACGATCGTGACCATGGACAGTGA CACCCCGTCTAGTCTGTTCAAAGACGCAACGAATGTCAAATCCATCAAATCTGACATAAAGGTCTTCGTCAGTGT GGGCGGCTGGACATTCTCCGATAACGGCACGGCCACCCAGCCGCTGTACGGCGAGATTGCTGCGTCGGCCACCAA GAGACAGACATTTGCTGACAACGTCGTCCACTTCCTTAAGCAGTATGGATTTGACGGCTTGGACATTGACTGGGA ATACCCAGGCGCCGGTGACCGAGGTGGAAGTGCCGAAGACACAGCCAACTATGTGCTCCTGCTACAGACGCTGCG CAAGACCTTCGACGCTAGCGGTAACGACTTTGGTCTGACATTTACGGCCCCGTCCTCCTACTGGTATCTGCGTTG GTTTGACTTGCCAAGCATGGTCAAGTACGCTGACTGGATCAATCTGATGACCTATGATCTGCACGGGGTCTGGGA TAGCACCGATCCCATTGGCAGTATTGTGCAAGCTCATACAAACCTGACAGAGATTAAGCAGTCTGCGGAGCTATT CTGGCGTGTAGATATCCCCCCAGAGAAGCTCGTCATGGGCTTTGGCTTCTATGGACGGTCTTTCACGCTTGCGGA CAAGTCGTGCACGAAACCTGGTTGTCCATTCAAGGGTGCCTCAAGTCCAGGCCCCTGCTCCGATACTGGTGGAAT CTTGGCTTACTATGAGATCCAAGCGATCTTAGATGGCACGAGTAGTTCCTCTAAGCGATCAACCATCACGCCAAT TCATGACAAGAATGATGCAGTCAATTATTTCACATTCGACGACGATCAGTGGGTTTCTTATGATGATGAGACAAC TTTTGCCCAAAAGGTGACGTGGGCCAACGAGGTTGGTCTTGGAGGCGCCATGATCTGGGCTTCAGATCTGGGTAA GATATAGCATCTGCGATTGAATATCTATTCCGCCAATAGTGAAGCATCACAGAACTAACTGGGAGCAGACGACGA CAAATACACGGCCCACGCAGGTCTCACCAATAAACCTATCATGACGAACCCGACCTTGAAGACCATAGACAAAGC CTTGTCCGACCCCAAGTCCGTCATTCAAGACCTAGCCAGCTTCAACGGCCAGAACTGCTTCAAATACGAAGGTAA ATGCGTCAACCTTAACGACAACAATGCCATGGCGGATGCTTGTGGCTCTGGATATACCGTTGTCGGGTGGGATGA CGCTGGATGCGGCAAATCGAATTGTGTAGGTTCTTACTCGTTTCCTGTCACGTTGTTATCTCTTCCACTTACACA TTTGCCTCCTATCAGCACTGTGGAAAGCCCATCTGCTGTCCGACGGGCTCCGCTCCAAAGAATTGCAACTGGCGT GGCGACAACACCGGTGATGCTGGCGTCTCATCAGACTGTAATGCGCAATGCAAATCGGGAGAAATCAACATCGCC GGCATTCGATCGTCATGGGGAGGTGGTTTTACCAATGATGGTAACACTGACAAGTGTGGCCGCGGATACAAGGTC TTTTGCTGCCCTGATCCTGAGTATAAAGAGGTCATTGACGGATGTGCCTACGCGGGCTGGTAAGTCCCGTCTTCA TGAACCTGAGAGGGATACTTCGAACGCTCAGAACCAAAGGCTAACTAGCAAACCATGGTAAATTAACAGCGGCAA AGATTGCCCTAGTGGAAGCACAGAGATGTTTAACAAGATCGACACTTGCGGGTACAAGGGTCAAAAATACTGCTG TACGTCTCCAGCCGACTTGTCTGACTGCCATTGGGTCGGAGGAAGTTCTGGCCAGGACTGCGCAAATGCCAAGTG CGCCTCCACGGAGCTGGCAGTTGACCGCGCTAGTTACGGTGACTCGAGCTCCTTATGCGACTGGAGCCGCCAGAA GGTCGCCTGCTGCACAGTCAAGAAGGCTGCACGGGAGCCAGCCAAGTGCGCTGCCGATCTGTGTACGCTGTTTCC CGGCTGGTGTCCAAGTAATAGCGATGAGACTTCTGTCAGCTACCGCAAGCGAGGTGAGCTCAACGTACTGGAGAA GCGTGGTGCCCGAGAGAAATATACTCTTATACTGGCCGGTGTGACTATCGAGGTCCTCGCCGCCGCATACCCGTC AATTGGAGATCTCTTCACGATCGCCCGAGCCGCTCAAGTTCAACGATGGGCTTTTTGGAAGAACAAAGGCTACTG CAATAGCAGAGTTCTATCCGTACTGTCTCTTCCGACTGGCGAGGTCGCCAAAGCCCTGTACGAAGGCTTGAACTC GGAGCACGTCATCGATAGGCAGGTCATTAAAAAGTTCATTGAGGCTGTGATATCGGGGACTTTGACATCCGGTGC CCAGCCAGATGGTCTCTTGCCCATGTCGGCCACCTGGTGGGCAACTAAGTGGAGGGAGGCCAATGCGGCCCTTGC AGGTCTTCCTGCGGTAGGCAGTGATAACGGAGCCCAGCCATCGAGTCCTAATGACCGAATCATGGAAGCTTTCGG GTCGACATTCAACCCGTACCCACTGCTGGCCACTGACGCTGGAATCAATGGAGCTAAGGGCAAACTCATGGGTCT CAAAGCTCCTTTTAGCATCAAAAATATAGAAAAATTGGCAAAGGCCGCTGTCAAGGCCGATACTGACGAGGCTGT GCAGGAGGTTCTAACAGCCCTTCAGAGCGTAAGGCCGCTTTTCCTTCTCGGGGGGGGGGGGGCGGGGGGGGGGGG GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGTGGGTGGGGGGGGGGGGGGGGNNNNNNNNNTAAAATTTTGA AATCCCGTGGTTTTTTCTCTTTAATCCGATGCCGTGTCTTTGGTTTTTAAAACCTCTCCTTTGGTTCCCGCGGGT TTTCTTTTCCACCCCCCCCCCCCCCCCAATCTTCTCTCGCTAACTGAATTTACCTAACAGGTGTTTGGCATGTTC GAGTACTTCGCCGACTATCGTGTCTCCAAGACGTATAACTGGGTTCTCCAAAGCGTCGGTCTGCAGATGGCCCAA GTCGAGTATGCTACCGGCGTTCAAGATCTGCAAAAATGGTGGTGGGCGTGGGCACCAGACTACTTCCAGACGGTA GAGGACTATTCCCAAGGTTGGGCCGTCGAAGCTATTCGGGCCGTTGCAGGAGCGTACGCCGCGGCTCGTGCCGAT GGGCGGAATCTGAAGACGAATGATGCCGTCGCGGCGGTGCTCAGCGAATTCGAGAGCAAGATCCAGAAGATGAGC ATGCCGAAGATCACGGCGACAGAGACTACCATCTCCGACTTGGACTCTCTAGACTAG