Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g3753.t1
Gene name
Location	scaffold_06:651597..655381
Strand	-
Gene length (bp)	3784
Transcript length (bp)	3405
Coding sequence length (bp)	3405
Protein length (aa)	1135

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF04499	SAPS	SIT4 phosphatase-associated protein	4.0E-198	172	795

GO

GO Term	Description	Terminal node
GO:0043666	regulation of phosphoprotein phosphatase activity	Yes
GO:0019903	protein phosphatase binding	Yes
GO:0065007	biological regulation	No
GO:0031323	regulation of cellular metabolic process	No
GO:0010921	regulation of phosphatase activity	No
GO:0051174	regulation of phosphorus metabolic process	No
GO:0050790	regulation of catalytic activity	No
GO:0008150	biological_process	No
GO:0019899	enzyme binding	No
GO:0060255	regulation of macromolecule metabolic process	No
GO:0019220	regulation of phosphate metabolic process	No
GO:0050789	regulation of biological process	No
GO:0005488	binding	No
GO:0031399	regulation of protein modification process	No
GO:0005515	protein binding	No
GO:0003674	molecular_function	No
GO:0065009	regulation of molecular function	No
GO:0051171	regulation of nitrogen compound metabolic process	No
GO:0051246	regulation of protein metabolic process	No
GO:0019222	regulation of metabolic process	No
GO:0051336	regulation of hydrolase activity	No
GO:0080090	regulation of primary metabolic process	No
GO:0035303	regulation of dephosphorylation	No
GO:0035304	regulation of protein dephosphorylation	No
GO:0050794	regulation of cellular process	No
GO:0019902	phosphatase binding	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 14	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g3753.t1 MFWRFGGYANLSTIDTLLDKPDLTLEELLDEPETIQELKQLNTKLIEYLREDHALKRLMEYVTAPSLVNDDEDDA KDTSEKGKDDAASAEQTDMDEEKEGDLRDILDPDDLDKVEKKRLTHAYIACEILSSETWSILESMMANPAYLGEF WGFLRRPPPLDSLQASYFTKVNETLLDKKTDEMLEFLNTLDGIVPALLQHVDNPMVMDLLLKIISLEKAEGGQGT VDWLRSQGLIPNLLSFLSPDRPASVQTSAGDFLKAIITISANASPNDQSCIGPNSLTRQLVSTECVQQLIDAMLK GGNPLTVGVGIVIEVIRKNNSDYDPESLGGPDTMLTTYDPIYLGTLLRLFAKHIPQFMALIQSSQHTIHEGNKLK TVERGKLNSAWGGQIEPLGFDRFKTCELMAELLHCSNMGLLNEPGSDEYVRQRDEERERLIREGGFDTRGFDTHQ DEHSGVDTAADFANDSALDSGSPEDAKVTEVPHVGEDDGFEDVGASGDLVSAKADADTTATANSQPTETVSETSP SEITEPEPVSSEETTDKSESSTTPIDPSSPTTGLSDQVSAMNLESEPQDEQQEPGKDNQEPVASLSQDVPAPLFS KEQASESDSAPADQSEEPSSLIEQVEETSVPNDGGDEDSAEQYIQLDTDGRPVVGDYLKIQFVENKVVPTILGFF FRFPWNNFLHNVVYDVIQQVFNGPMERGYNRALAVDVFDTGRITTAIVEGQKRSDETQRTKQIRLGYMGHLTLVA EEVVKFSERHPPELLSRSVMESVLNPDWIEYVEQTLSETRERDNAILGGVRPDISVGPRQTSLNNTNSGQGFSNS ALADVGLNGGIGGSTFQSFDLGQGGVSGGAFGGGGTSLLSGFASSSDDEDEEMEDQDERDSGNADQNDNDNCLGN VGLTKTGIMPVFTSSASQPIPILPPPPAPLSLGPSRARRQLAARLAAQKQQPSENEGDGDYRGAEGSEDRESDWP DNPFVIAGIDDPADAGSSAFPNSDFGSADGKHSPTFPESGFSPPDSLSTNSSEDEGDGHAESVRRQVRVPLEVED DDDDEMGEMVGPSGIGMMDSDDEDEAIINESLGYSNLSGPARYNNFRSRAVSSHYDDEQNDSSDGEDDGLVEIMV PGRKASTSN*
Coding	>Pro_DTO377G3_2|g3753.t1 ATGTTTTGGCGCTTTGGGGGATATGCGAATCTTTCCACCATCGATACCCTGCTCGACAAACCCGATCTCACTCTT GAGGAACTCTTAGACGAGCCCGAAACTATTCAAGAACTGAAACAGCTTAATACGAAACTCATTGAATATCTGCGC GAGGATCATGCCTTGAAACGGCTTATGGAATACGTCACGGCACCGAGCTTGGTGAATGACGACGAAGATGATGCG AAAGACACTTCAGAGAAGGGCAAGGATGATGCCGCTTCTGCGGAGCAGACAGATATGGACGAGGAGAAGGAAGGG GATCTGAGGGATATTCTTGACCCGGATGACCTAGACAAAGTCGAAAAGAAGCGTCTGACGCATGCCTATATCGCC TGTGAGATTCTCTCATCAGAGACATGGTCCATCCTCGAATCCATGATGGCCAACCCTGCATACTTGGGCGAATTC TGGGGTTTCCTGCGACGACCTCCTCCTCTTGATTCATTGCAGGCAAGCTACTTCACGAAAGTAAACGAGACTTTG CTTGATAAAAAGACCGACGAGATGCTGGAGTTTCTCAACACCCTTGATGGAATTGTCCCAGCATTGTTGCAGCAT GTTGATAACCCGATGGTCATGGATCTTCTCTTGAAAATTATCAGTCTTGAGAAGGCAGAGGGTGGCCAGGGCACT GTTGACTGGCTCAGATCCCAGGGTTTGATCCCCAATCTTCTGTCTTTCTTGTCCCCCGATCGTCCGGCGTCCGTT CAAACCTCTGCAGGTGACTTCCTGAAAGCGATCATCACTATATCTGCAAACGCAAGCCCGAACGACCAGTCATGT ATTGGTCCTAACAGTTTGACACGCCAGCTTGTCTCCACCGAGTGCGTACAGCAGCTCATCGATGCGATGCTCAAG GGTGGCAATCCCCTGACTGTGGGCGTGGGTATTGTCATCGAGGTAATTCGCAAGAACAATTCCGACTATGATCCG GAGTCCCTTGGCGGACCCGATACAATGCTCACCACTTACGACCCAATCTACCTTGGAACGTTGCTGCGTCTCTTC GCTAAACATATTCCCCAGTTCATGGCTCTCATTCAAAGTTCCCAGCACACTATTCATGAGGGAAATAAGCTCAAG ACTGTTGAGCGAGGAAAGTTGAACTCTGCTTGGGGTGGGCAAATTGAGCCTCTTGGTTTCGACCGATTCAAGACG TGTGAATTAATGGCGGAGCTGCTTCATTGCAGTAATATGGGTCTTCTGAATGAACCAGGCAGCGACGAGTATGTT AGGCAACGAGACGAGGAGCGTGAGCGGTTAATCCGTGAAGGAGGGTTCGATACGCGAGGCTTCGATACACACCAA GATGAGCATTCTGGAGTTGATACCGCGGCCGATTTTGCGAACGATTCAGCCCTCGATTCTGGATCCCCAGAAGAT GCCAAGGTCACAGAAGTGCCACACGTGGGTGAAGATGACGGATTTGAAGATGTTGGCGCATCTGGTGATTTAGTG AGTGCAAAAGCTGATGCCGACACAACGGCTACTGCAAACTCGCAGCCGACGGAAACGGTCAGCGAAACCTCTCCA TCGGAAATCACAGAGCCAGAGCCGGTGTCTTCCGAAGAAACCACGGATAAATCTGAAAGTTCCACCACACCCATT GATCCCTCGTCGCCTACTACTGGTCTCTCTGATCAAGTCAGCGCCATGAATCTTGAAAGTGAACCACAAGACGAG CAGCAGGAGCCTGGAAAGGACAACCAGGAGCCTGTGGCTTCCCTCTCCCAAGATGTTCCAGCTCCTCTCTTCTCC AAGGAACAAGCATCCGAGTCAGACTCCGCCCCAGCCGATCAATCGGAAGAACCATCTAGTCTTATTGAACAGGTC GAGGAAACGAGCGTTCCGAACGACGGAGGCGATGAGGACTCGGCCGAACAATACATCCAACTCGATACTGACGGG CGACCTGTGGTCGGCGATTACCTGAAGATCCAGTTCGTGGAGAATAAAGTTGTCCCAACGATTCTGGGCTTCTTC TTCCGCTTCCCATGGAATAACTTCCTGCACAATGTTGTTTACGATGTGATTCAACAAGTCTTTAATGGGCCCATG GAGCGTGGCTACAATCGGGCACTCGCAGTCGATGTATTTGACACCGGACGAATCACTACCGCGATTGTTGAAGGG CAGAAGCGCAGCGATGAGACCCAGCGGACTAAGCAAATCCGTCTCGGATATATGGGACACCTTACTCTTGTTGCG GAGGAGGTCGTCAAGTTCAGCGAGCGTCATCCGCCAGAGTTACTCTCACGGTCCGTTATGGAGAGCGTGTTGAAT CCCGACTGGATTGAGTACGTCGAACAAACTTTATCAGAGACTCGCGAACGCGACAATGCTATTCTCGGCGGTGTT CGTCCTGATATATCGGTTGGGCCTCGCCAGACTAGCCTTAACAACACCAACTCTGGCCAAGGCTTCTCTAACTCC GCTCTGGCGGACGTGGGATTGAATGGAGGAATCGGTGGCTCAACCTTCCAGAGTTTCGACCTCGGCCAAGGAGGT GTTTCCGGTGGAGCATTCGGCGGAGGTGGCACCTCCCTTTTGAGTGGCTTTGCCAGCTCAAGCGACGACGAGGAC GAAGAAATGGAGGACCAGGACGAGAGAGACTCCGGCAATGCCGATCAAAATGACAATGACAATTGCTTGGGCAAT GTGGGCTTGACTAAAACTGGTATCATGCCTGTGTTCACAAGTTCAGCCAGTCAACCTATTCCTATCTTACCCCCG CCACCTGCTCCATTGAGCTTGGGCCCTTCCCGCGCACGCCGTCAGTTAGCCGCACGTCTTGCCGCTCAAAAGCAA CAACCATCAGAAAATGAAGGCGACGGAGATTACAGGGGGGCCGAAGGAAGTGAGGACCGAGAGTCAGATTGGCCG GATAACCCATTCGTAATTGCAGGGATCGATGACCCCGCCGACGCAGGCAGCTCTGCGTTCCCTAATAGTGACTTT GGTTCAGCCGATGGCAAACACTCACCTACCTTCCCGGAATCAGGATTCAGCCCTCCAGACTCGCTATCAACTAAC TCATCTGAAGATGAAGGTGATGGCCACGCAGAATCCGTGAGGCGACAGGTTCGTGTCCCTCTAGAAGTCGAGGAT GACGACGATGATGAAATGGGTGAGATGGTCGGGCCGAGTGGCATTGGCATGATGGACTCCGACGACGAAGACGAG GCTATCATAAACGAATCTCTTGGTTACTCCAACCTCTCGGGCCCCGCCCGATACAACAACTTCCGATCACGAGCC GTGAGCTCCCATTATGATGATGAGCAAAACGACAGCAGTGATGGCGAAGATGATGGATTGGTGGAGATAATGGTC CCTGGCCGCAAGGCCTCGACCTCGAACTAA
Transcript	>Pro_DTO377G3_2|g3753.t1 ATGTTTTGGCGCTTTGGGGGATATGCGAATCTTTCCACCATCGATACCCTGCTCGACAAACCCGATCTCACTCTT GAGGAACTCTTAGACGAGCCCGAAACTATTCAAGAACTGAAACAGCTTAATACGAAACTCATTGAATATCTGCGC GAGGATCATGCCTTGAAACGGCTTATGGAATACGTCACGGCACCGAGCTTGGTGAATGACGACGAAGATGATGCG AAAGACACTTCAGAGAAGGGCAAGGATGATGCCGCTTCTGCGGAGCAGACAGATATGGACGAGGAGAAGGAAGGG GATCTGAGGGATATTCTTGACCCGGATGACCTAGACAAAGTCGAAAAGAAGCGTCTGACGCATGCCTATATCGCC TGTGAGATTCTCTCATCAGAGACATGGTCCATCCTCGAATCCATGATGGCCAACCCTGCATACTTGGGCGAATTC TGGGGTTTCCTGCGACGACCTCCTCCTCTTGATTCATTGCAGGCAAGCTACTTCACGAAAGTAAACGAGACTTTG CTTGATAAAAAGACCGACGAGATGCTGGAGTTTCTCAACACCCTTGATGGAATTGTCCCAGCATTGTTGCAGCAT GTTGATAACCCGATGGTCATGGATCTTCTCTTGAAAATTATCAGTCTTGAGAAGGCAGAGGGTGGCCAGGGCACT GTTGACTGGCTCAGATCCCAGGGTTTGATCCCCAATCTTCTGTCTTTCTTGTCCCCCGATCGTCCGGCGTCCGTT CAAACCTCTGCAGGTGACTTCCTGAAAGCGATCATCACTATATCTGCAAACGCAAGCCCGAACGACCAGTCATGT ATTGGTCCTAACAGTTTGACACGCCAGCTTGTCTCCACCGAGTGCGTACAGCAGCTCATCGATGCGATGCTCAAG GGTGGCAATCCCCTGACTGTGGGCGTGGGTATTGTCATCGAGGTAATTCGCAAGAACAATTCCGACTATGATCCG GAGTCCCTTGGCGGACCCGATACAATGCTCACCACTTACGACCCAATCTACCTTGGAACGTTGCTGCGTCTCTTC GCTAAACATATTCCCCAGTTCATGGCTCTCATTCAAAGTTCCCAGCACACTATTCATGAGGGAAATAAGCTCAAG ACTGTTGAGCGAGGAAAGTTGAACTCTGCTTGGGGTGGGCAAATTGAGCCTCTTGGTTTCGACCGATTCAAGACG TGTGAATTAATGGCGGAGCTGCTTCATTGCAGTAATATGGGTCTTCTGAATGAACCAGGCAGCGACGAGTATGTT AGGCAACGAGACGAGGAGCGTGAGCGGTTAATCCGTGAAGGAGGGTTCGATACGCGAGGCTTCGATACACACCAA GATGAGCATTCTGGAGTTGATACCGCGGCCGATTTTGCGAACGATTCAGCCCTCGATTCTGGATCCCCAGAAGAT GCCAAGGTCACAGAAGTGCCACACGTGGGTGAAGATGACGGATTTGAAGATGTTGGCGCATCTGGTGATTTAGTG AGTGCAAAAGCTGATGCCGACACAACGGCTACTGCAAACTCGCAGCCGACGGAAACGGTCAGCGAAACCTCTCCA TCGGAAATCACAGAGCCAGAGCCGGTGTCTTCCGAAGAAACCACGGATAAATCTGAAAGTTCCACCACACCCATT GATCCCTCGTCGCCTACTACTGGTCTCTCTGATCAAGTCAGCGCCATGAATCTTGAAAGTGAACCACAAGACGAG CAGCAGGAGCCTGGAAAGGACAACCAGGAGCCTGTGGCTTCCCTCTCCCAAGATGTTCCAGCTCCTCTCTTCTCC AAGGAACAAGCATCCGAGTCAGACTCCGCCCCAGCCGATCAATCGGAAGAACCATCTAGTCTTATTGAACAGGTC GAGGAAACGAGCGTTCCGAACGACGGAGGCGATGAGGACTCGGCCGAACAATACATCCAACTCGATACTGACGGG CGACCTGTGGTCGGCGATTACCTGAAGATCCAGTTCGTGGAGAATAAAGTTGTCCCAACGATTCTGGGCTTCTTC TTCCGCTTCCCATGGAATAACTTCCTGCACAATGTTGTTTACGATGTGATTCAACAAGTCTTTAATGGGCCCATG GAGCGTGGCTACAATCGGGCACTCGCAGTCGATGTATTTGACACCGGACGAATCACTACCGCGATTGTTGAAGGG CAGAAGCGCAGCGATGAGACCCAGCGGACTAAGCAAATCCGTCTCGGATATATGGGACACCTTACTCTTGTTGCG GAGGAGGTCGTCAAGTTCAGCGAGCGTCATCCGCCAGAGTTACTCTCACGGTCCGTTATGGAGAGCGTGTTGAAT CCCGACTGGATTGAGTACGTCGAACAAACTTTATCAGAGACTCGCGAACGCGACAATGCTATTCTCGGCGGTGTT CGTCCTGATATATCGGTTGGGCCTCGCCAGACTAGCCTTAACAACACCAACTCTGGCCAAGGCTTCTCTAACTCC GCTCTGGCGGACGTGGGATTGAATGGAGGAATCGGTGGCTCAACCTTCCAGAGTTTCGACCTCGGCCAAGGAGGT GTTTCCGGTGGAGCATTCGGCGGAGGTGGCACCTCCCTTTTGAGTGGCTTTGCCAGCTCAAGCGACGACGAGGAC GAAGAAATGGAGGACCAGGACGAGAGAGACTCCGGCAATGCCGATCAAAATGACAATGACAATTGCTTGGGCAAT GTGGGCTTGACTAAAACTGGTATCATGCCTGTGTTCACAAGTTCAGCCAGTCAACCTATTCCTATCTTACCCCCG CCACCTGCTCCATTGAGCTTGGGCCCTTCCCGCGCACGCCGTCAGTTAGCCGCACGTCTTGCCGCTCAAAAGCAA CAACCATCAGAAAATGAAGGCGACGGAGATTACAGGGGGGCCGAAGGAAGTGAGGACCGAGAGTCAGATTGGCCG GATAACCCATTCGTAATTGCAGGGATCGATGACCCCGCCGACGCAGGCAGCTCTGCGTTCCCTAATAGTGACTTT GGTTCAGCCGATGGCAAACACTCACCTACCTTCCCGGAATCAGGATTCAGCCCTCCAGACTCGCTATCAACTAAC TCATCTGAAGATGAAGGTGATGGCCACGCAGAATCCGTGAGGCGACAGGTTCGTGTCCCTCTAGAAGTCGAGGAT GACGACGATGATGAAATGGGTGAGATGGTCGGGCCGAGTGGCATTGGCATGATGGACTCCGACGACGAAGACGAG GCTATCATAAACGAATCTCTTGGTTACTCCAACCTCTCGGGCCCCGCCCGATACAACAACTTCCGATCACGAGCC GTGAGCTCCCATTATGATGATGAGCAAAACGACAGCAGTGATGGCGAAGATGATGGATTGGTGGAGATAATGGTC CCTGGCCGCAAGGCCTCGACCTCGAACTAA
Gene	>Pro_DTO377G3_2|g3753.t1 ATGTTTTGGCGCTTTGGGGGATATGCGAATCTTTCCACCATCGATACCCTGCTCGACAAACCCGATCTCACTCTT GAGGAACTCTTAGACGAGCCCGAAACTATTCAAGAACTGAAACAGCTTAATACGAAACTCATTGAATATCTGCGC GAGGATCATGCCTTGAAACGGCTTATGGAATACGTCACGGCACCGAGCTTGGTGAATGACGACGAAGATGATGCG AAAGACACTTCAGAGAAGGGCAAGGATGATGCCGCTTCTGCGGAGCAGACAGATATGGACGAGGAGAAGGAAGGG GATCTGAGGGATATTCTTGACCCGGATGACCTAGACAAAGTCGAAAAGAAGCGTCTGACGCATGCCTATATCGCC TGTGAGATTCTCTCATCAGAGACATGGTCCATCCTCGAATCCATGATGGCCAACCCTGCATACTTGGGCGAATTC TGGGGTTTCCTGCGACGACCTCCTCCTCTTGATTCATTGCAGGCAAGCTACTTCACGAAAGTAAACGAGACTTTG CTTGATAAAAAGACCGACGAGATGCTGGAGTTTCTCAACACCCTTGATGGAATTGTCCCAGCATTGTTGCAGCAT GTTGATAACCCGATGGTCATGGATCTTCTCTTGAAAATTATCAGTCTTGAGAAGGCAGAGGGTGGCCAGGGCACT GTTGACTGGCTCAGATCCCAGGGTTTGATCCCCAATCTTCTGTCTTTCTTGTCCCCCGATCGTCCGGCGTCCGTT CAAACCTCTGCAGGTGACTTCCTGAAAGCGATCATCACTATATCTGCAAACGCAAGCCCGAACGACCAGTCATGT ATTGGTCCTAACAGTTTGACACGCCAGCTTGTCTCCACCGAGTGCGTACAGCAGCTCATCGATGCGATGCTCAAG GGTGGCAATCCCCTGACTGTGGGCGTGGGTATTGTCATCGAGGTAATTCGCAAGAACAATTCCGACTATGATCCG GAGTCCCTTGGCGGACCCGATACAATGCTCACCACTTACGACCCAATCTACCTTGGAACGTTGCTGCGTCTCTTC GCTAAACATATTCCCCAGTTCATGGCTCTCATTCAAAGTTCCCAGCACACTATTCATGAGGGAAATAAGCTCAAG ACTGTTGAGCGAGGAAAGTTGAACTCTGCTTGGGGTGGGCAAATTGAGCCTCTTGGTTTCGACCGATTCAAGACG TGTGAATTAATGGCGGAGCTGCTTCATTGCAGTAATATGGGTCTTCTGAATGAACCAGGCAGCGACGAGTATGTT AGGCAACGAGACGAGGAGCGTGAGCGGTTAATCCGTGAAGGAGGGTTCGATACGCGAGGCTTCGATACACACCAA GATGAGCATTCTGGAGTTGATACCGCGGCCGATTTTGCGAACGATTCAGCCCTCGATTCTGGATCCCCAGAAGAT GCCAAGGTCACAGAAGTGCCACACGTGGGTGAAGATGACGGATTTGAAGATGTTGGCGCATCTGGTGATTTAGTG AGTGCAAAAGCTGATGCCGACACAACGGCTACTGCAAACTCGCAGCCGACGGAAACGGTCAGCGAAACCTCTCCA TCGGAAATCACAGAGCCAGAGCCGGTGTCTTCCGAAGAAACCACGGATAAATCTGAAAGTTCCACCACACCCATT GATCCCTCGTCGCCTACTACTGGTCTCTCTGATCAAGTCAGCGCCATGAATCTTGAAAGTGAACCACAAGACGAG CAGCAGGAGCCTGGAAAGGACAACCAGGAGCCTGTGGCTTCCCTCTCCCAAGATGTTCCAGCTCCTCTCTTCTCC AAGGAACAAGCATCCGAGTCAGACTCCGCCCCAGCCGATCAATCGGAAGAACCATCTAGTCTTATTGAACAGGTC GAGGAAACGAGCGTTCCGAACGACGGAGGCGATGAGGACTCGGCCGAACAATACATCCAACTCGATACTGACGGG CGACCTGTGGTCGGCGATTACCTGAAGATCCAGTTCGTGGAGAATAAAGTTGTCCCAACGATTCTGGTTTGTATT TCTTTTAGAGAACGTTGAACACCCACGCTAACCATTGATAGGGCTTCTTCTTCCGCTTCCCATGGAATAACTTCC TGCACAATGTTGTTTACGATGTGATTCAACAAGTCTTTAATGGGCCCATGGAGCGTGGCTACAATCGGGCACTCG CAGTCGATGTATTTGACACCGGACGAATCACTACCGCGATTGTTGAAGGGCAGAAGCGCAGCGATGAGACCCAGC GGACTAAGCAAATCCGTCTCGGATATATGGGACACCTTACTCTTGTTGCGGAGGAGGTCGTCAAGTTCAGCGAGC GTCATCCGCCAGAGTTACTCTCACGGTCCGTTATGGAGAGCGTGTTGAATCCCGACTGGATTGAGTACGTCGAAC AAACTTTATCAGAGACTCGCGAACGCGACAATGCTATTCTCGGCGGTGTTCGTCCTGATATATCGGTTGGGCCTC GCCAGACTAGCCTTAACAACACCAACTCTGGCCAAGGCTTCTCTAACTCCGCTCTGGCGGACGTGGGATTGAATG GAGGAATCGGTGGCTCAACCTTCCAGAGTTTCGACCTCGGCCAAGGAGGTGTTTCCGGTGGAGCATTCGGCGGAG GTGGCACCTCCCTTTTGAGTGGCTTTGCCAGCTCAAGCGACGACGAGGACGAAGAAATGGAGGACCAGGACGAGA GAGACTCCGGCAATGCCGATCAAAATGACAATGACAATGTGGGTTACCTCTTCCGATGGACATGATGGTGCACGA TCTCAACCGATTCCGTGCATCCCCCATTATCTTCACCATTCCTTCCCGGTTTACCCCTCATGTATCCCAAGCTAT AGCAAGGGCCAAAGAGCCAGAATTCCAGGTAAAGTGCTGGATCGCTAGTGCTTGGGCAATGTGGGCTTGACTAAA ACTGGTATCATGCCTGTTAGCTGATGTTCATTGCCGATATCGTGTTGCAAATCTCAGCCCAGGGGAGGGGGGATT CTCGTGTCACTTTGTCCTGAACTGGGTTTCTTATGCACTTTTCCCTTTCCCTTTACAAGGAATGGGCTGTCAGAT GTATTGTCTTTTTACTAACTGACTTTCTATTAAGGTGTTCACAAGTTCAGCCAGTCAACCTATTCCTATCTTACC CCCGCCACCTGCTCCATTGAGCTTGGGCCCTTCCCGCGCACGCCGTCAGTTAGCCGCACGTCTTGCCGCTCAAAA GCAACAACCATCAGAAAATGAAGGCGACGGAGATTACAGGGGGGCCGAAGGAAGTGAGGACCGAGAGTCAGATTG GCCGGATAACCCATTCGTAATTGCAGGGATCGATGACCCCGCCGACGCAGGCAGCTCTGCGTTCCCTAATAGTGA CTTTGGTTCAGCCGATGGCAAACACTCACCTACCTTCCCGGAATCAGGATTCAGCCCTCCAGACTCGCTATCAAC TAACTCATCTGAAGATGAAGGTGATGGCCACGCAGAATCCGTGAGGCGACAGGTTCGTGTCCCTCTAGAAGTCGA GGATGACGACGATGATGAAATGGGTGAGATGGTCGGGCCGAGTGGCATTGGCATGATGGACTCCGACGACGAAGA CGAGGCTATCATAAACGAATCTCTTGGTTACTCCAACCTCTCGGGCCCCGCCCGATACAACAACTTCCGATCACG AGCCGTGAGCTCCCATTATGATGATGAGCAAAACGACAGCAGTGATGGCGAAGATGATGGATTGGTGGAGATAAT GGTCCCTGGCCGCAAGGCCTCGACCTCGAACTAA