Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g374.t1
Gene name
Location	scaffold_01:949800..953294
Strand	-
Gene length (bp)	3494
Transcript length (bp)	3426
Coding sequence length (bp)	3426
Protein length (aa)	1142

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF18136	DNApol_Exo	DNA mitochondrial polymerase exonuclease domain	1.3E-106	117	395
PF00476	DNA_pol_A	DNA polymerase family A	2.3E-40	597	947

GO

GO Term	Description	Terminal node
GO:0003887	DNA-directed DNA polymerase activity	Yes
GO:0003677	DNA binding	Yes
GO:0006260	DNA replication	Yes
GO:0005488	binding	No
GO:0003824	catalytic activity	No
GO:0006139	nucleobase-containing compound metabolic process	No
GO:0016772	transferase activity, transferring phosphorus-containing groups	No
GO:0006259	DNA metabolic process	No
GO:0008150	biological_process	No
GO:0006725	cellular aromatic compound metabolic process	No
GO:1901360	organic cyclic compound metabolic process	No
GO:0071704	organic substance metabolic process	No
GO:0003676	nucleic acid binding	No
GO:0016740	transferase activity	No
GO:0043170	macromolecule metabolic process	No
GO:0044260	cellular macromolecule metabolic process	No
GO:0008152	metabolic process	No
GO:0140640	catalytic activity, acting on a nucleic acid	No
GO:0034641	cellular nitrogen compound metabolic process	No
GO:0046483	heterocycle metabolic process	No
GO:0003674	molecular_function	No
GO:0006807	nitrogen compound metabolic process	No
GO:0097159	organic cyclic compound binding	No
GO:1901363	heterocyclic compound binding	No
GO:0016779	nucleotidyltransferase activity	No
GO:0090304	nucleic acid metabolic process	No
GO:0044237	cellular metabolic process	No
GO:0140097	catalytic activity, acting on DNA	No
GO:0009987	cellular process	No
GO:0044238	primary metabolic process	No
GO:0034061	DNA polymerase activity	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 15	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g374.t1 MLSWKFSCTPCSKGAVESFLRRSSPFLVKPPSCYQSDRSHTRLFSTSADNVTTRRSLSVPSSSRFNDIGVQQLSD HVHAQVFPNKGRVPDPELVALSKDHLARHELLGKSQNGAGPIAFDLPALKGQTLDEHFYKLGMDSSEPYLSWAKS YAALTCPAKPRKWVQRSGWTKYHTDGTSEPVDAPNESMLTFDTEVMYKDNPFAVMACAVSPTAWYAWISPWLLGE SENQVQLIPLGDPTQSRIVVGHNIGYDRARVLEEYNMQQSQNFFLDTMSLHVAVNGMCSQQRPTWMRHKKNQDMR DKIANDHDSVELAALLENNMLREEEEELWVGRSSVNSLRDVAKFHCDVTIDKAQRDLFGELDRDSIVARLEELLD YCAADVAITHRVYRKVFPNFLETCPHPVSFGALRHLSSVILPVNESWEEYLTSAEETYHKRLDDVQSKLLALCDE ALKYKDQPDIYTIDPWLQQLDWSGQEIKMAKGKKKGDPPRPAARQKKPGMPKWYKDLFTSNAADINLTVRTRIAP ILLKLSWDNYPLVWSDLHGWTFRVPRDQIKQYENQPVVMCDMTEEKNTELRDDRKAIYFKIPHKDGPQARCTNPL GKGYMQYFERGILSSQYELAKQALDMNASCSYWISARDRIKGQIVVYEDQAQKGREKSEAGDNRIGFILPQVIPM GTITRRAVENTWLTASNAKANRVGSELKAMIKAPPGYSFVGADVDSQELWIASLVGDAPFQIHGGNAIGFMCLEG SKAEGTDLHSRSASILGISRNDAKVFNYGRIYGAGVKFAATLLRQFNPSLTEKQTQETAKNLYKETKGTRTSRRL LSETPFWRGGTESFVFNKLEEFADQERPRTPALGAGITEALMRRFINKGSFMTSRINWAIQSSGVDYLHLLIVSM DYLIRRFNIQARLAITVHDEIRYLVKDEDRYRAAMALQIANVWTRALFSQQVGIDDLPQSCAYFSAVDIDHVLRK EVDMDCVTPSHPHKIPHGETLDITQLLDKDQEAFLDPSITPQSPPNPDKYPYTPRESVMSAFQASNDIDFIKAQI TKDDKELRDIIKEKTRAAASVIAPTPRTPSTKPKGTSTNWSSAKPQRAVLMDMESGLYPDFHGSRPSFHGNKQPQ IGLHRPPWKPRAIARV*
Coding	>Pro_DTO377G3_2|g374.t1 ATGTTATCTTGGAAGTTCTCCTGCACTCCTTGTTCCAAGGGTGCCGTGGAATCTTTCTTGCGACGAAGCTCGCCG TTCCTGGTTAAGCCGCCATCGTGCTACCAGTCAGACAGAAGTCATACAAGATTATTCTCTACTTCCGCCGACAAT GTGACCACAAGACGATCTCTTTCTGTCCCTTCCTCATCCAGATTCAATGACATCGGAGTCCAACAGCTCAGCGAC CATGTCCATGCTCAAGTTTTCCCCAACAAAGGTCGCGTTCCGGACCCAGAACTAGTCGCTCTCTCGAAGGATCAT TTAGCTCGACATGAGCTCCTGGGCAAATCTCAAAATGGCGCCGGTCCTATCGCATTCGATCTTCCTGCTCTCAAG GGACAAACGTTGGACGAACACTTCTACAAACTTGGAATGGATTCTTCCGAACCATACCTGTCATGGGCTAAGTCA TATGCGGCTCTTACCTGTCCGGCCAAACCACGCAAATGGGTCCAACGCAGCGGATGGACGAAATACCACACTGAC GGAACCTCTGAACCTGTCGACGCCCCAAATGAATCAATGTTAACATTCGACACCGAGGTCATGTACAAAGATAAT CCATTTGCGGTCATGGCTTGCGCGGTAAGCCCGACAGCTTGGTATGCATGGATATCACCGTGGCTGCTTGGCGAG TCAGAGAATCAAGTACAGCTGATACCCTTGGGAGACCCCACTCAATCTCGCATTGTGGTTGGCCACAATATTGGT TACGACCGAGCCCGAGTCCTTGAGGAATACAACATGCAGCAGTCTCAAAACTTCTTTCTCGACACAATGTCCCTA CATGTGGCGGTCAACGGCATGTGTTCGCAACAGAGACCGACTTGGATGCGCCACAAAAAGAATCAGGACATGAGA GATAAAATCGCGAATGACCACGATTCTGTGGAGCTTGCCGCACTTCTCGAAAACAACATGTTGAGAGAAGAAGAG GAGGAGCTTTGGGTTGGGCGAAGCTCGGTGAACTCCCTGCGTGATGTGGCCAAATTCCATTGTGATGTCACTATC GATAAGGCGCAGAGAGATCTGTTCGGTGAACTTGATCGTGACTCTATTGTGGCCAGACTGGAGGAACTTCTCGAC TATTGTGCTGCCGATGTTGCCATCACCCACCGTGTCTACCGAAAAGTTTTCCCCAATTTTCTCGAGACTTGCCCG CATCCCGTCAGTTTCGGTGCTCTTCGACACTTATCCTCCGTCATTTTACCAGTCAATGAGTCATGGGAAGAGTAT CTTACCAGCGCAGAGGAAACATATCATAAGCGGCTGGACGATGTCCAGAGTAAACTACTAGCACTATGCGACGAA GCATTGAAGTATAAAGACCAACCAGACATTTACACGATTGATCCTTGGCTACAACAGCTGGACTGGTCCGGCCAG GAGATCAAAATGGCCAAAGGAAAGAAGAAGGGTGATCCACCTCGGCCGGCAGCGAGGCAAAAGAAACCAGGAATG CCCAAGTGGTACAAGGATCTTTTTACCTCCAACGCCGCCGATATTAACTTGACGGTGCGGACTCGCATTGCGCCA ATTCTGCTCAAACTTTCCTGGGACAACTATCCTCTTGTTTGGTCGGACCTGCACGGATGGACTTTCCGCGTTCCT CGTGATCAAATCAAACAGTATGAGAATCAGCCAGTCGTCATGTGCGATATGACCGAGGAAAAGAACACCGAGTTG CGAGACGATAGAAAAGCCATATACTTCAAAATCCCCCACAAGGACGGCCCACAAGCTAGGTGTACCAATCCGCTT GGAAAAGGGTATATGCAGTATTTCGAACGTGGGATCCTGTCATCTCAGTATGAACTTGCCAAACAAGCGCTGGAT ATGAATGCGTCATGTTCTTATTGGATCAGCGCCCGGGATCGAATCAAGGGTCAAATCGTGGTCTATGAAGATCAG GCGCAAAAAGGCAGAGAGAAAAGTGAAGCCGGCGATAATCGTATCGGATTTATTCTGCCTCAAGTCATTCCAATG GGGACCATCACTCGACGCGCCGTGGAAAATACTTGGTTGACTGCAAGTAATGCGAAGGCCAACCGTGTTGGGTCA GAGCTAAAAGCTATGATCAAAGCACCGCCGGGCTACTCGTTCGTTGGAGCCGATGTCGACTCCCAGGAATTATGG ATTGCAAGTCTTGTCGGAGATGCCCCATTCCAGATTCACGGAGGAAACGCAATCGGCTTCATGTGCTTAGAAGGG TCTAAAGCTGAGGGGACGGATCTTCACTCACGAAGTGCGTCGATTCTGGGAATCTCGCGGAATGACGCCAAGGTC TTCAACTACGGCCGAATCTACGGGGCAGGCGTCAAGTTCGCCGCTACTTTACTTCGCCAGTTCAATCCGTCTCTA ACTGAAAAGCAGACACAAGAGACTGCCAAGAACCTGTACAAAGAGACTAAGGGAACGCGCACTTCACGTCGCCTC TTGAGTGAGACGCCGTTTTGGCGAGGTGGCACTGAATCCTTTGTGTTCAATAAACTCGAAGAGTTTGCGGATCAG GAACGACCTAGAACCCCTGCTTTGGGTGCTGGGATCACTGAGGCGCTCATGCGACGTTTCATTAATAAAGGCAGC TTCATGACATCCCGAATCAATTGGGCTATTCAGTCGTCGGGTGTCGATTATCTTCACCTCTTGATCGTTAGCATG GACTATCTTATCCGACGATTCAACATTCAGGCCCGCTTGGCCATCACTGTTCACGATGAAATTCGCTACCTTGTC AAAGATGAGGATAGGTATCGCGCTGCAATGGCTTTGCAGATTGCCAACGTTTGGACTCGTGCCTTATTCTCTCAG CAAGTAGGAATTGATGACCTCCCCCAATCATGTGCCTACTTCTCCGCCGTCGACATTGACCATGTCCTTCGCAAA GAAGTCGACATGGACTGTGTGACCCCTTCTCATCCTCACAAAATTCCGCATGGTGAAACGCTGGATATTACTCAG CTCCTAGACAAGGATCAGGAAGCTTTCTTGGACCCGTCCATCACACCCCAGTCGCCTCCAAATCCCGACAAATAC CCATACACTCCACGGGAGTCGGTCATGTCCGCTTTCCAAGCTTCCAATGACATTGATTTCATCAAAGCTCAAATC ACCAAAGATGACAAAGAGCTTCGCGATATCATCAAGGAGAAGACGCGCGCAGCTGCTAGTGTCATCGCTCCTACT CCTCGCACCCCTTCTACCAAACCGAAAGGTACTTCTACCAATTGGAGCTCGGCAAAGCCCCAGCGGGCGGTTCTG ATGGACATGGAGTCAGGCCTCTATCCCGACTTCCACGGCTCCCGGCCTAGTTTTCATGGGAATAAACAGCCTCAA ATTGGACTCCACCGTCCTCCCTGGAAACCACGGGCAATAGCCCGAGTATAA
Transcript	>Pro_DTO377G3_2|g374.t1 ATGTTATCTTGGAAGTTCTCCTGCACTCCTTGTTCCAAGGGTGCCGTGGAATCTTTCTTGCGACGAAGCTCGCCG TTCCTGGTTAAGCCGCCATCGTGCTACCAGTCAGACAGAAGTCATACAAGATTATTCTCTACTTCCGCCGACAAT GTGACCACAAGACGATCTCTTTCTGTCCCTTCCTCATCCAGATTCAATGACATCGGAGTCCAACAGCTCAGCGAC CATGTCCATGCTCAAGTTTTCCCCAACAAAGGTCGCGTTCCGGACCCAGAACTAGTCGCTCTCTCGAAGGATCAT TTAGCTCGACATGAGCTCCTGGGCAAATCTCAAAATGGCGCCGGTCCTATCGCATTCGATCTTCCTGCTCTCAAG GGACAAACGTTGGACGAACACTTCTACAAACTTGGAATGGATTCTTCCGAACCATACCTGTCATGGGCTAAGTCA TATGCGGCTCTTACCTGTCCGGCCAAACCACGCAAATGGGTCCAACGCAGCGGATGGACGAAATACCACACTGAC GGAACCTCTGAACCTGTCGACGCCCCAAATGAATCAATGTTAACATTCGACACCGAGGTCATGTACAAAGATAAT CCATTTGCGGTCATGGCTTGCGCGGTAAGCCCGACAGCTTGGTATGCATGGATATCACCGTGGCTGCTTGGCGAG TCAGAGAATCAAGTACAGCTGATACCCTTGGGAGACCCCACTCAATCTCGCATTGTGGTTGGCCACAATATTGGT TACGACCGAGCCCGAGTCCTTGAGGAATACAACATGCAGCAGTCTCAAAACTTCTTTCTCGACACAATGTCCCTA CATGTGGCGGTCAACGGCATGTGTTCGCAACAGAGACCGACTTGGATGCGCCACAAAAAGAATCAGGACATGAGA GATAAAATCGCGAATGACCACGATTCTGTGGAGCTTGCCGCACTTCTCGAAAACAACATGTTGAGAGAAGAAGAG GAGGAGCTTTGGGTTGGGCGAAGCTCGGTGAACTCCCTGCGTGATGTGGCCAAATTCCATTGTGATGTCACTATC GATAAGGCGCAGAGAGATCTGTTCGGTGAACTTGATCGTGACTCTATTGTGGCCAGACTGGAGGAACTTCTCGAC TATTGTGCTGCCGATGTTGCCATCACCCACCGTGTCTACCGAAAAGTTTTCCCCAATTTTCTCGAGACTTGCCCG CATCCCGTCAGTTTCGGTGCTCTTCGACACTTATCCTCCGTCATTTTACCAGTCAATGAGTCATGGGAAGAGTAT CTTACCAGCGCAGAGGAAACATATCATAAGCGGCTGGACGATGTCCAGAGTAAACTACTAGCACTATGCGACGAA GCATTGAAGTATAAAGACCAACCAGACATTTACACGATTGATCCTTGGCTACAACAGCTGGACTGGTCCGGCCAG GAGATCAAAATGGCCAAAGGAAAGAAGAAGGGTGATCCACCTCGGCCGGCAGCGAGGCAAAAGAAACCAGGAATG CCCAAGTGGTACAAGGATCTTTTTACCTCCAACGCCGCCGATATTAACTTGACGGTGCGGACTCGCATTGCGCCA ATTCTGCTCAAACTTTCCTGGGACAACTATCCTCTTGTTTGGTCGGACCTGCACGGATGGACTTTCCGCGTTCCT CGTGATCAAATCAAACAGTATGAGAATCAGCCAGTCGTCATGTGCGATATGACCGAGGAAAAGAACACCGAGTTG CGAGACGATAGAAAAGCCATATACTTCAAAATCCCCCACAAGGACGGCCCACAAGCTAGGTGTACCAATCCGCTT GGAAAAGGGTATATGCAGTATTTCGAACGTGGGATCCTGTCATCTCAGTATGAACTTGCCAAACAAGCGCTGGAT ATGAATGCGTCATGTTCTTATTGGATCAGCGCCCGGGATCGAATCAAGGGTCAAATCGTGGTCTATGAAGATCAG GCGCAAAAAGGCAGAGAGAAAAGTGAAGCCGGCGATAATCGTATCGGATTTATTCTGCCTCAAGTCATTCCAATG GGGACCATCACTCGACGCGCCGTGGAAAATACTTGGTTGACTGCAAGTAATGCGAAGGCCAACCGTGTTGGGTCA GAGCTAAAAGCTATGATCAAAGCACCGCCGGGCTACTCGTTCGTTGGAGCCGATGTCGACTCCCAGGAATTATGG ATTGCAAGTCTTGTCGGAGATGCCCCATTCCAGATTCACGGAGGAAACGCAATCGGCTTCATGTGCTTAGAAGGG TCTAAAGCTGAGGGGACGGATCTTCACTCACGAAGTGCGTCGATTCTGGGAATCTCGCGGAATGACGCCAAGGTC TTCAACTACGGCCGAATCTACGGGGCAGGCGTCAAGTTCGCCGCTACTTTACTTCGCCAGTTCAATCCGTCTCTA ACTGAAAAGCAGACACAAGAGACTGCCAAGAACCTGTACAAAGAGACTAAGGGAACGCGCACTTCACGTCGCCTC TTGAGTGAGACGCCGTTTTGGCGAGGTGGCACTGAATCCTTTGTGTTCAATAAACTCGAAGAGTTTGCGGATCAG GAACGACCTAGAACCCCTGCTTTGGGTGCTGGGATCACTGAGGCGCTCATGCGACGTTTCATTAATAAAGGCAGC TTCATGACATCCCGAATCAATTGGGCTATTCAGTCGTCGGGTGTCGATTATCTTCACCTCTTGATCGTTAGCATG GACTATCTTATCCGACGATTCAACATTCAGGCCCGCTTGGCCATCACTGTTCACGATGAAATTCGCTACCTTGTC AAAGATGAGGATAGGTATCGCGCTGCAATGGCTTTGCAGATTGCCAACGTTTGGACTCGTGCCTTATTCTCTCAG CAAGTAGGAATTGATGACCTCCCCCAATCATGTGCCTACTTCTCCGCCGTCGACATTGACCATGTCCTTCGCAAA GAAGTCGACATGGACTGTGTGACCCCTTCTCATCCTCACAAAATTCCGCATGGTGAAACGCTGGATATTACTCAG CTCCTAGACAAGGATCAGGAAGCTTTCTTGGACCCGTCCATCACACCCCAGTCGCCTCCAAATCCCGACAAATAC CCATACACTCCACGGGAGTCGGTCATGTCCGCTTTCCAAGCTTCCAATGACATTGATTTCATCAAAGCTCAAATC ACCAAAGATGACAAAGAGCTTCGCGATATCATCAAGGAGAAGACGCGCGCAGCTGCTAGTGTCATCGCTCCTACT CCTCGCACCCCTTCTACCAAACCGAAAGGTACTTCTACCAATTGGAGCTCGGCAAAGCCCCAGCGGGCGGTTCTG ATGGACATGGAGTCAGGCCTCTATCCCGACTTCCACGGCTCCCGGCCTAGTTTTCATGGGAATAAACAGCCTCAA ATTGGACTCCACCGTCCTCCCTGGAAACCACGGGCAATAGCCCGAGTATAA
Gene	>Pro_DTO377G3_2|g374.t1 ATGTTATCTTGGAAGTTCTCCTGCACTCCTTGTTCCAAGGGTGCCGTGGAATCTTTCTTGCGACGAAGCTCGCCG TTCCTGGTTAAGCCGCCATCGTGCTACCAGTCAGACAGAAGTCATACAAGATTATTCTCTACTTCCGCCGACAAT GTGACCACAAGACGATCTCTTTCTGGTGGGTGCCCTGTCTTTTGCGCTTCTCGATAAGAAAACAATCAAATCGCA ATTACTGATCTCGCGCAGTCCCTTCCTCATCCAGATTCAATGACATCGGAGTCCAACAGCTCAGCGACCATGTCC ATGCTCAAGTTTTCCCCAACAAAGGTCGCGTTCCGGACCCAGAACTAGTCGCTCTCTCGAAGGATCATTTAGCTC GACATGAGCTCCTGGGCAAATCTCAAAATGGCGCCGGTCCTATCGCATTCGATCTTCCTGCTCTCAAGGGACAAA CGTTGGACGAACACTTCTACAAACTTGGAATGGATTCTTCCGAACCATACCTGTCATGGGCTAAGTCATATGCGG CTCTTACCTGTCCGGCCAAACCACGCAAATGGGTCCAACGCAGCGGATGGACGAAATACCACACTGACGGAACCT CTGAACCTGTCGACGCCCCAAATGAATCAATGTTAACATTCGACACCGAGGTCATGTACAAAGATAATCCATTTG CGGTCATGGCTTGCGCGGTAAGCCCGACAGCTTGGTATGCATGGATATCACCGTGGCTGCTTGGCGAGTCAGAGA ATCAAGTACAGCTGATACCCTTGGGAGACCCCACTCAATCTCGCATTGTGGTTGGCCACAATATTGGTTACGACC GAGCCCGAGTCCTTGAGGAATACAACATGCAGCAGTCTCAAAACTTCTTTCTCGACACAATGTCCCTACATGTGG CGGTCAACGGCATGTGTTCGCAACAGAGACCGACTTGGATGCGCCACAAAAAGAATCAGGACATGAGAGATAAAA TCGCGAATGACCACGATTCTGTGGAGCTTGCCGCACTTCTCGAAAACAACATGTTGAGAGAAGAAGAGGAGGAGC TTTGGGTTGGGCGAAGCTCGGTGAACTCCCTGCGTGATGTGGCCAAATTCCATTGTGATGTCACTATCGATAAGG CGCAGAGAGATCTGTTCGGTGAACTTGATCGTGACTCTATTGTGGCCAGACTGGAGGAACTTCTCGACTATTGTG CTGCCGATGTTGCCATCACCCACCGTGTCTACCGAAAAGTTTTCCCCAATTTTCTCGAGACTTGCCCGCATCCCG TCAGTTTCGGTGCTCTTCGACACTTATCCTCCGTCATTTTACCAGTCAATGAGTCATGGGAAGAGTATCTTACCA GCGCAGAGGAAACATATCATAAGCGGCTGGACGATGTCCAGAGTAAACTACTAGCACTATGCGACGAAGCATTGA AGTATAAAGACCAACCAGACATTTACACGATTGATCCTTGGCTACAACAGCTGGACTGGTCCGGCCAGGAGATCA AAATGGCCAAAGGAAAGAAGAAGGGTGATCCACCTCGGCCGGCAGCGAGGCAAAAGAAACCAGGAATGCCCAAGT GGTACAAGGATCTTTTTACCTCCAACGCCGCCGATATTAACTTGACGGTGCGGACTCGCATTGCGCCAATTCTGC TCAAACTTTCCTGGGACAACTATCCTCTTGTTTGGTCGGACCTGCACGGATGGACTTTCCGCGTTCCTCGTGATC AAATCAAACAGTATGAGAATCAGCCAGTCGTCATGTGCGATATGACCGAGGAAAAGAACACCGAGTTGCGAGACG ATAGAAAAGCCATATACTTCAAAATCCCCCACAAGGACGGCCCACAAGCTAGGTGTACCAATCCGCTTGGAAAAG GGTATATGCAGTATTTCGAACGTGGGATCCTGTCATCTCAGTATGAACTTGCCAAACAAGCGCTGGATATGAATG CGTCATGTTCTTATTGGATCAGCGCCCGGGATCGAATCAAGGGTCAAATCGTGGTCTATGAAGATCAGGCGCAAA AAGGCAGAGAGAAAAGTGAAGCCGGCGATAATCGTATCGGATTTATTCTGCCTCAAGTCATTCCAATGGGGACCA TCACTCGACGCGCCGTGGAAAATACTTGGTTGACTGCAAGTAATGCGAAGGCCAACCGTGTTGGGTCAGAGCTAA AAGCTATGATCAAAGCACCGCCGGGCTACTCGTTCGTTGGAGCCGATGTCGACTCCCAGGAATTATGGATTGCAA GTCTTGTCGGAGATGCCCCATTCCAGATTCACGGAGGAAACGCAATCGGCTTCATGTGCTTAGAAGGGTCTAAAG CTGAGGGGACGGATCTTCACTCACGAAGTGCGTCGATTCTGGGAATCTCGCGGAATGACGCCAAGGTCTTCAACT ACGGCCGAATCTACGGGGCAGGCGTCAAGTTCGCCGCTACTTTACTTCGCCAGTTCAATCCGTCTCTAACTGAAA AGCAGACACAAGAGACTGCCAAGAACCTGTACAAAGAGACTAAGGGAACGCGCACTTCACGTCGCCTCTTGAGTG AGACGCCGTTTTGGCGAGGTGGCACTGAATCCTTTGTGTTCAATAAACTCGAAGAGTTTGCGGATCAGGAACGAC CTAGAACCCCTGCTTTGGGTGCTGGGATCACTGAGGCGCTCATGCGACGTTTCATTAATAAAGGCAGCTTCATGA CATCCCGAATCAATTGGGCTATTCAGTCGTCGGGTGTCGATTATCTTCACCTCTTGATCGTTAGCATGGACTATC TTATCCGACGATTCAACATTCAGGCCCGCTTGGCCATCACTGTTCACGATGAAATTCGCTACCTTGTCAAAGATG AGGATAGGTATCGCGCTGCAATGGCTTTGCAGATTGCCAACGTTTGGACTCGTGCCTTATTCTCTCAGCAAGTAG GAATTGATGACCTCCCCCAATCATGTGCCTACTTCTCCGCCGTCGACATTGACCATGTCCTTCGCAAAGAAGTCG ACATGGACTGTGTGACCCCTTCTCATCCTCACAAAATTCCGCATGGTGAAACGCTGGATATTACTCAGCTCCTAG ACAAGGATCAGGAAGCTTTCTTGGACCCGTCCATCACACCCCAGTCGCCTCCAAATCCCGACAAATACCCATACA CTCCACGGGAGTCGGTCATGTCCGCTTTCCAAGCTTCCAATGACATTGATTTCATCAAAGCTCAAATCACCAAAG ATGACAAAGAGCTTCGCGATATCATCAAGGAGAAGACGCGCGCAGCTGCTAGTGTCATCGCTCCTACTCCTCGCA CCCCTTCTACCAAACCGAAAGGTACTTCTACCAATTGGAGCTCGGCAAAGCCCCAGCGGGCGGTTCTGATGGACA TGGAGTCAGGCCTCTATCCCGACTTCCACGGCTCCCGGCCTAGTTTTCATGGGAATAAACAGCCTCAAATTGGAC TCCACCGTCCTCCCTGGAAACCACGGGCAATAGCCCGAGTATAA