Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g2709.t1
Gene name
Location	scaffold_03:742564..746629
Strand	+
Gene length (bp)	4065
Transcript length (bp)	3756
Coding sequence length (bp)	3756
Protein length (aa)	1252

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00689	Cation_ATPase_C	Cation transporting ATPase, C-terminus	2.3E-47	969	1148
PF00122	E1-E2_ATPase	E1-E2 ATPase	5.3E-37	327	536
PF00702	Hydrolase	haloacid dehalogenase-like hydrolase	8.1E-19	555	896
PF13246	Cation_ATPase	Cation transport ATPase (P-type)	4.1E-19	616	703
PF00690	Cation_ATPase_N	Cation transporter/ATPase, N-terminus	1.2E-07	230	273

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	262	283	21
2	288	310	22
3	461	483	22
4	503	525	22
5	942	964	22
6	1020	1039	19
7	1093	1115	22
8	1125	1144	19
9	1151	1168	17

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g2709.t1 MSSSNNDPSYQGSLLSPVIVTDFSGRERSMSTASSAWSGPTDLNHSPTSPVSPDMAWNPPDPARLMVQNASHRLS QSIDGDTLRPRADSFASSADTVVRSRANSEVDPTHTSKDVYDDVSLSDALKPDPRNEADFQVEDNRFAFSPGQLN KMQNPKSLAAFHALGGLQGLERGLRTDLKAGLSIDEGCLEGNVEFQDVAPSAQHTATEKSPSKPVTSAPAPVSSG HGSPFEDRIRVFSQNKLPARKSTGFLKLFWAAYNDKIIILLTIAAVVSLSLGIYETVSEGTGVQWVEGVAICVAI LIVTIVTAANDWQKERQFAKLNKRNDDRQVQVTRSGKPDMVSIYDIMVGDILHLEAGDSIPADGILVSGYGVKCD ESSATGESDQMKKTPGHEVWQQIVDGKATKKLDPFLISGSKVLEGLGTYVVTSVGPYSTYGRILLSLQTPNDPTP LQVKLGKLADWIGYLGTAAAGILFFVLLFRFVADLPNHPERNGAVKGKEFVDILIVAVTVIVVAIPEGLPLAVTL ALAFATTRMVKENNLVRVLRACETMGNATVICSDKTGTLTQNKMTVVAGTWGSNQNFSQRTEDEDVEGSMTTSAI SQKLSAPIKDLIIKSIALNSTAFEREKDGSIDFVGSKTEVAMLQLARDYMGMDLVSERGSAEITQLIPFDSDRKC MGVVYRVPGAGYRLLVKGASELMVGVCTAEIVNIDISKERPDVEQLSDEQKKNLLEIIDNYAHKSLRTIGIVYKD FASWPPIEAKHSEDPSANFEDFFHDMTWVGVVGIQDPLRPEVPSAIRKCHSAGVQVKMVTGDNVATATAIATSCG IKTEDGLVMEGPKFRQLTNEEMDEVVPRLQVLARSSPEDKRILVERLKALGETVAVTGDGTNDGPALRTADVGFS MGIAGTEVAKEASSIILLDDNFKSIITAIAWGRAVNDAVAKFLQFQVTVNITAVILTFVSSVYSSENTSVLTAVQ LLWVNLIMDTFAALALATDAPTEKILDRKPVSKHASLFTMTMWKMILGQAVYQLAITFMLYFAGEKLLNAHLSSE PEMRAKQLSTVVFNTFVWMQIFNEFNNRRLDNKFNIFEGMFRNYWFLGINAIMIGGQVMIVFVGGQAFNVTRLNG TLWGVCLICSIACLPWAIVLRLIPDYYFGLVFNAVVGGMAVVLRPLSKGCKVIGRGIRSFFRPVKRFTRRIFNKR KSEDELELKPKSTDPEEAPERLQLNTQKPSPERLATPTPVVIPPITITTSP*
Coding	>Pro_DTO377G3_2|g2709.t1 ATGTCTTCTTCAAACAATGACCCCTCCTATCAGGGCTCGCTATTGAGTCCTGTTATAGTGACGGACTTTTCAGGC AGAGAGCGATCTATGTCTACAGCCTCTTCTGCATGGTCGGGTCCTACAGATCTAAATCACAGCCCGACTTCTCCT GTCTCACCAGATATGGCGTGGAACCCACCAGACCCAGCTCGGCTGATGGTTCAAAATGCCTCGCATCGACTGTCA CAGTCGATCGATGGCGATACATTGCGTCCGCGGGCGGATTCATTCGCTTCTTCAGCAGATACCGTAGTTCGTTCG CGGGCGAACTCCGAGGTAGACCCGACCCATACTTCCAAAGATGTCTACGACGATGTCTCGCTGTCGGATGCTTTG AAACCGGACCCGAGGAATGAAGCCGATTTCCAGGTGGAGGATAATCGGTTTGCGTTCTCCCCGGGTCAACTGAAC AAAATGCAGAACCCAAAGTCCTTGGCTGCATTCCATGCTCTTGGTGGCTTACAAGGTCTGGAGCGGGGTCTGCGA ACAGATCTCAAGGCCGGTTTGTCAATTGATGAAGGGTGTCTGGAGGGCAATGTCGAGTTCCAGGATGTGGCACCT TCAGCGCAACACACAGCTACAGAAAAATCTCCATCAAAACCTGTCACCTCGGCGCCGGCGCCGGTGTCATCTGGT CATGGTTCACCATTCGAAGACCGCATTCGTGTCTTCAGTCAGAACAAACTACCTGCTCGGAAATCGACCGGGTTC CTGAAATTATTTTGGGCTGCATATAATGACAAAATTATTATATTATTGACCATTGCCGCCGTGGTCTCGCTATCC CTGGGGATATACGAGACCGTGTCGGAAGGCACAGGCGTCCAGTGGGTGGAAGGAGTCGCCATCTGTGTAGCAATC TTGATTGTTACAATCGTTACAGCTGCGAACGATTGGCAAAAAGAGAGACAATTTGCCAAGCTCAATAAACGGAAC GATGACCGTCAAGTTCAAGTCACCCGCTCAGGCAAACCCGACATGGTTTCAATCTACGATATTATGGTCGGCGAT ATCCTCCATCTCGAGGCAGGCGATTCCATCCCAGCAGATGGAATTCTAGTTTCAGGCTACGGGGTGAAGTGCGAT GAGTCTTCCGCCACCGGCGAGTCGGATCAAATGAAGAAGACCCCTGGCCATGAAGTCTGGCAGCAAATTGTCGAC GGCAAGGCAACCAAGAAACTCGACCCGTTTCTGATCTCCGGTAGCAAGGTCCTTGAAGGGTTGGGAACTTATGTT GTCACCAGTGTTGGACCCTATTCTACCTACGGACGGATCTTGTTGTCGCTGCAGACTCCTAATGACCCAACGCCG CTTCAAGTCAAGCTGGGTAAGTTGGCGGATTGGATTGGGTATTTGGGTACAGCAGCTGCTGGTATTCTGTTCTTT GTTTTGCTATTCCGCTTTGTAGCCGATCTGCCCAATCACCCGGAAAGGAACGGTGCTGTGAAAGGCAAAGAGTTT GTGGATATTCTTATTGTTGCTGTCACGGTTATTGTTGTCGCTATTCCAGAGGGTCTCCCACTAGCAGTAACGCTG GCTTTGGCCTTCGCTACTACCCGTATGGTCAAGGAGAACAACCTAGTCCGCGTCCTTCGCGCATGCGAGACAATG GGAAACGCCACGGTCATCTGCTCTGATAAAACAGGCACATTGACACAGAACAAAATGACCGTTGTGGCCGGAACC TGGGGCTCGAACCAAAACTTCAGCCAGAGAACCGAAGATGAAGATGTGGAAGGTTCAATGACTACTTCGGCCATC TCCCAGAAACTATCAGCTCCCATCAAAGATTTGATTATCAAGAGCATCGCTTTGAACTCAACTGCGTTTGAACGG GAAAAGGACGGCTCCATCGATTTTGTCGGTAGTAAGACCGAGGTTGCGATGCTTCAGTTGGCTAGGGATTATATG GGCATGGATCTTGTCTCGGAGCGTGGCTCCGCTGAGATCACCCAATTGATTCCTTTCGACTCCGACAGGAAGTGC ATGGGTGTTGTTTACCGTGTTCCTGGAGCTGGCTACCGACTGCTTGTCAAGGGAGCGTCCGAGTTGATGGTCGGC GTCTGCACCGCAGAAATTGTCAACATTGATATTTCCAAAGAGAGACCCGATGTGGAGCAGCTTTCTGACGAACAA AAGAAAAACCTTCTGGAGATCATCGACAATTATGCCCACAAGTCTCTTCGAACGATTGGCATAGTCTACAAGGAC TTCGCAAGCTGGCCACCGATCGAAGCCAAACATTCTGAGGATCCTTCAGCAAACTTCGAGGATTTCTTCCATGAT ATGACTTGGGTTGGAGTTGTAGGTATCCAAGACCCTCTTCGCCCCGAAGTCCCATCGGCCATTCGCAAATGTCAC TCGGCAGGCGTCCAGGTCAAGATGGTGACTGGTGACAACGTTGCCACTGCCACTGCTATTGCAACTTCTTGCGGA ATCAAGACGGAAGATGGATTGGTCATGGAAGGTCCCAAGTTCCGCCAACTCACAAACGAGGAGATGGATGAAGTG GTTCCGCGCCTGCAAGTGCTGGCACGATCATCCCCCGAAGACAAGCGAATCTTGGTCGAACGTCTCAAGGCCCTC GGTGAAACGGTCGCCGTGACAGGTGATGGTACCAACGACGGACCGGCTTTGCGGACTGCAGATGTCGGCTTCTCC ATGGGTATTGCTGGTACTGAGGTCGCGAAGGAGGCGAGTTCGATTATTCTCCTGGATGATAATTTCAAGTCCATC ATCACAGCGATCGCTTGGGGACGAGCTGTTAATGACGCCGTTGCCAAGTTTTTGCAATTCCAGGTCACGGTCAAT ATCACGGCCGTGATCCTCACTTTTGTGTCATCTGTGTACAGCAGCGAGAACACCAGTGTTTTGACAGCTGTGCAG CTGCTCTGGGTGAACCTGATCATGGACACATTCGCCGCTCTCGCCTTAGCCACGGATGCCCCGACTGAAAAGATT CTCGACCGCAAGCCTGTCTCCAAACACGCCTCCCTTTTCACAATGACCATGTGGAAGATGATTCTTGGCCAAGCA GTATACCAGCTAGCCATCACATTCATGCTTTATTTCGCAGGCGAAAAGCTCCTCAACGCCCATCTCAGCTCCGAG CCCGAGATGCGCGCGAAACAACTCTCGACCGTGGTGTTCAACACGTTCGTGTGGATGCAGATCTTCAACGAATTC AACAATCGCCGCCTCGACAACAAGTTCAATATCTTCGAAGGCATGTTCCGCAATTACTGGTTCTTAGGAATCAAC GCCATCATGATCGGTGGCCAGGTCATGATCGTCTTCGTGGGCGGCCAGGCATTCAACGTGACTCGCTTGAACGGC ACCCTCTGGGGCGTGTGTTTGATCTGTTCTATTGCCTGCTTGCCCTGGGCTATCGTGCTCCGACTTATCCCAGAC TACTATTTCGGGCTTGTTTTCAATGCCGTTGTTGGCGGTATGGCTGTTGTTTTGCGCCCGCTTTCCAAGGGGTGC AAGGTAATCGGTCGAGGCATCAGGTCTTTCTTTAGGCCTGTGAAGCGTTTCACTCGCCGTATTTTCAACAAGCGG AAGTCAGAAGATGAACTCGAGTTGAAACCAAAGTCTACTGATCCTGAAGAAGCTCCTGAGAGACTACAACTGAAC ACGCAAAAGCCCTCTCCTGAGCGTCTGGCCACGCCTACTCCTGTCGTCATTCCCCCTATCACGATTACTACGTCT CCTTAG
Transcript	>Pro_DTO377G3_2|g2709.t1 ATGTCTTCTTCAAACAATGACCCCTCCTATCAGGGCTCGCTATTGAGTCCTGTTATAGTGACGGACTTTTCAGGC AGAGAGCGATCTATGTCTACAGCCTCTTCTGCATGGTCGGGTCCTACAGATCTAAATCACAGCCCGACTTCTCCT GTCTCACCAGATATGGCGTGGAACCCACCAGACCCAGCTCGGCTGATGGTTCAAAATGCCTCGCATCGACTGTCA CAGTCGATCGATGGCGATACATTGCGTCCGCGGGCGGATTCATTCGCTTCTTCAGCAGATACCGTAGTTCGTTCG CGGGCGAACTCCGAGGTAGACCCGACCCATACTTCCAAAGATGTCTACGACGATGTCTCGCTGTCGGATGCTTTG AAACCGGACCCGAGGAATGAAGCCGATTTCCAGGTGGAGGATAATCGGTTTGCGTTCTCCCCGGGTCAACTGAAC AAAATGCAGAACCCAAAGTCCTTGGCTGCATTCCATGCTCTTGGTGGCTTACAAGGTCTGGAGCGGGGTCTGCGA ACAGATCTCAAGGCCGGTTTGTCAATTGATGAAGGGTGTCTGGAGGGCAATGTCGAGTTCCAGGATGTGGCACCT TCAGCGCAACACACAGCTACAGAAAAATCTCCATCAAAACCTGTCACCTCGGCGCCGGCGCCGGTGTCATCTGGT CATGGTTCACCATTCGAAGACCGCATTCGTGTCTTCAGTCAGAACAAACTACCTGCTCGGAAATCGACCGGGTTC CTGAAATTATTTTGGGCTGCATATAATGACAAAATTATTATATTATTGACCATTGCCGCCGTGGTCTCGCTATCC CTGGGGATATACGAGACCGTGTCGGAAGGCACAGGCGTCCAGTGGGTGGAAGGAGTCGCCATCTGTGTAGCAATC TTGATTGTTACAATCGTTACAGCTGCGAACGATTGGCAAAAAGAGAGACAATTTGCCAAGCTCAATAAACGGAAC GATGACCGTCAAGTTCAAGTCACCCGCTCAGGCAAACCCGACATGGTTTCAATCTACGATATTATGGTCGGCGAT ATCCTCCATCTCGAGGCAGGCGATTCCATCCCAGCAGATGGAATTCTAGTTTCAGGCTACGGGGTGAAGTGCGAT GAGTCTTCCGCCACCGGCGAGTCGGATCAAATGAAGAAGACCCCTGGCCATGAAGTCTGGCAGCAAATTGTCGAC GGCAAGGCAACCAAGAAACTCGACCCGTTTCTGATCTCCGGTAGCAAGGTCCTTGAAGGGTTGGGAACTTATGTT GTCACCAGTGTTGGACCCTATTCTACCTACGGACGGATCTTGTTGTCGCTGCAGACTCCTAATGACCCAACGCCG CTTCAAGTCAAGCTGGGTAAGTTGGCGGATTGGATTGGGTATTTGGGTACAGCAGCTGCTGGTATTCTGTTCTTT GTTTTGCTATTCCGCTTTGTAGCCGATCTGCCCAATCACCCGGAAAGGAACGGTGCTGTGAAAGGCAAAGAGTTT GTGGATATTCTTATTGTTGCTGTCACGGTTATTGTTGTCGCTATTCCAGAGGGTCTCCCACTAGCAGTAACGCTG GCTTTGGCCTTCGCTACTACCCGTATGGTCAAGGAGAACAACCTAGTCCGCGTCCTTCGCGCATGCGAGACAATG GGAAACGCCACGGTCATCTGCTCTGATAAAACAGGCACATTGACACAGAACAAAATGACCGTTGTGGCCGGAACC TGGGGCTCGAACCAAAACTTCAGCCAGAGAACCGAAGATGAAGATGTGGAAGGTTCAATGACTACTTCGGCCATC TCCCAGAAACTATCAGCTCCCATCAAAGATTTGATTATCAAGAGCATCGCTTTGAACTCAACTGCGTTTGAACGG GAAAAGGACGGCTCCATCGATTTTGTCGGTAGTAAGACCGAGGTTGCGATGCTTCAGTTGGCTAGGGATTATATG GGCATGGATCTTGTCTCGGAGCGTGGCTCCGCTGAGATCACCCAATTGATTCCTTTCGACTCCGACAGGAAGTGC ATGGGTGTTGTTTACCGTGTTCCTGGAGCTGGCTACCGACTGCTTGTCAAGGGAGCGTCCGAGTTGATGGTCGGC GTCTGCACCGCAGAAATTGTCAACATTGATATTTCCAAAGAGAGACCCGATGTGGAGCAGCTTTCTGACGAACAA AAGAAAAACCTTCTGGAGATCATCGACAATTATGCCCACAAGTCTCTTCGAACGATTGGCATAGTCTACAAGGAC TTCGCAAGCTGGCCACCGATCGAAGCCAAACATTCTGAGGATCCTTCAGCAAACTTCGAGGATTTCTTCCATGAT ATGACTTGGGTTGGAGTTGTAGGTATCCAAGACCCTCTTCGCCCCGAAGTCCCATCGGCCATTCGCAAATGTCAC TCGGCAGGCGTCCAGGTCAAGATGGTGACTGGTGACAACGTTGCCACTGCCACTGCTATTGCAACTTCTTGCGGA ATCAAGACGGAAGATGGATTGGTCATGGAAGGTCCCAAGTTCCGCCAACTCACAAACGAGGAGATGGATGAAGTG GTTCCGCGCCTGCAAGTGCTGGCACGATCATCCCCCGAAGACAAGCGAATCTTGGTCGAACGTCTCAAGGCCCTC GGTGAAACGGTCGCCGTGACAGGTGATGGTACCAACGACGGACCGGCTTTGCGGACTGCAGATGTCGGCTTCTCC ATGGGTATTGCTGGTACTGAGGTCGCGAAGGAGGCGAGTTCGATTATTCTCCTGGATGATAATTTCAAGTCCATC ATCACAGCGATCGCTTGGGGACGAGCTGTTAATGACGCCGTTGCCAAGTTTTTGCAATTCCAGGTCACGGTCAAT ATCACGGCCGTGATCCTCACTTTTGTGTCATCTGTGTACAGCAGCGAGAACACCAGTGTTTTGACAGCTGTGCAG CTGCTCTGGGTGAACCTGATCATGGACACATTCGCCGCTCTCGCCTTAGCCACGGATGCCCCGACTGAAAAGATT CTCGACCGCAAGCCTGTCTCCAAACACGCCTCCCTTTTCACAATGACCATGTGGAAGATGATTCTTGGCCAAGCA GTATACCAGCTAGCCATCACATTCATGCTTTATTTCGCAGGCGAAAAGCTCCTCAACGCCCATCTCAGCTCCGAG CCCGAGATGCGCGCGAAACAACTCTCGACCGTGGTGTTCAACACGTTCGTGTGGATGCAGATCTTCAACGAATTC AACAATCGCCGCCTCGACAACAAGTTCAATATCTTCGAAGGCATGTTCCGCAATTACTGGTTCTTAGGAATCAAC GCCATCATGATCGGTGGCCAGGTCATGATCGTCTTCGTGGGCGGCCAGGCATTCAACGTGACTCGCTTGAACGGC ACCCTCTGGGGCGTGTGTTTGATCTGTTCTATTGCCTGCTTGCCCTGGGCTATCGTGCTCCGACTTATCCCAGAC TACTATTTCGGGCTTGTTTTCAATGCCGTTGTTGGCGGTATGGCTGTTGTTTTGCGCCCGCTTTCCAAGGGGTGC AAGGTAATCGGTCGAGGCATCAGGTCTTTCTTTAGGCCTGTGAAGCGTTTCACTCGCCGTATTTTCAACAAGCGG AAGTCAGAAGATGAACTCGAGTTGAAACCAAAGTCTACTGATCCTGAAGAAGCTCCTGAGAGACTACAACTGAAC ACGCAAAAGCCCTCTCCTGAGCGTCTGGCCACGCCTACTCCTGTCGTCATTCCCCCTATCACGATTACTACGTCT CCTTAG
Gene	>Pro_DTO377G3_2|g2709.t1 ATGTCTTCTTCAAACAATGACCCCTCCTATCAGGGCTCGCTATTGAGTCCTGTTATAGTGACGGACTTTTCAGGC AGAGAGGTAGGCCACTCAAGCTATTTCATCATTCTATAAACATCTGGAAATTTGTCGCTAATTGTTTTATTTTCT TTCTCTTCCAGCGATCTATGTCTACAGCCTCTTCTGCATGGTCGGGTCCTACAGATCTAAATCACAGCCCGACTT CTCCTGTCTCACCAGATATGGCGTGGAACCCACCAGACCCAGCTCGGCTGATGGTTCAAAATGCCTCGCATCGAC TGTCACAGTCGATCGATGGCGATACATTGCGTCCGCGGGCGGATTCATTCGCTTCTTCAGCAGATACCGTAGTTC GTTCGCGGGCGAACTCCGAGGTAGACCCGACCCATACTTCCAAAGATGTCTACGACGATGTCTCGCTGTCGGATG CTTTGAAACCGGACCCGAGGAATGAAGCCGATTTCCAGGTGGAGGATAATCGGTTTGCGTTCTCCCCGGGTCAAC TGAACAAAATGCAGAACCCAAAGTCCTTGGCTGCATTCCATGCTCTTGGTGGCTTACAAGGTCTGGAGCGGGGTC TGCGAACAGATCTCAAGGCCGGTTTGTCAATTGATGAAGGGTGTCTGGAGGGCAATGTCGAGTTCCAGGATGTGG CACCTTCAGCGCAACACACAGCTACAGAAAAATCTCCATCAAAACCTGTCACCTCGGCGCCGGCGCCGGTGTCAT CTGGTCATGGTTCACCATTCGAAGACCGCATTCGTGTCTTCAGTCAGAACAAACTACCTGCTCGGAAATCGACCG GGTTCCTGAAATTATTTTGGGCTGCATATAATGACAAAATTATTATATTATTGACCATTGCCGCCGTGGTCTCGC TATCCCTGGGGATATACGAGACCGTGTCGGAAGGCACAGGCGTCCAGTGGGTGGAAGGAGTCGCCATCTGTGTAG CAATCTTGATTGTTACAATCGTTACAGCTGCGAACGATTGGCAAAAAGAGAGACAATTTGCCAAGCTCAATAAAC GGGCAGGTCTTCCCCTATCAATCCAGAAACTGAGCACAGCTAACATGCCAACAGAACGATGACCGTCAAGTTCAA GTCACCCGCTCAGGCAAACCCGACATGGTTTCAATCTACGATATTATGGTCGGCGATATCCTCCATCTCGAGGCA GGCGATTCCATCCCAGCAGATGGAATTCTAGTTTCAGGCTACGGGGTGAAGTGCGATGAGTCTTCCGCCACCGGC GAGTCGGATCAAATGAAGAAGACCCCTGGCCATGAAGTCTGGCAGCAAATTGTCGACGGCAAGGCAACCAAGAAA CTCGACCCGTTTCTGATCTCCGGTAGCAAGGTCCTTGAAGGGTTGGGAACTTATGTTGTCACCAGTGTTGGACCC TATTCTACCTACGGACGGATCTTGTTGTCGCTGCAGACTCCTAATGACCCAACGCCGCTTCAAGTCAAGCTGGGT AAGTTGGCGGATTGGATTGGGTATTTGGGTACAGCGTGAGTTGACTTTCATACTTCCCTTTTGTTGTACAGGTTA CTGATGGTGAGACAGAGCTGCTGGTATTCTGTTCTTTGTTTTGCTATTCCGCTTTGTAGCCGATCTGCCCAATCA CCCGGAAAGGAACGGTGCTGTGAAAGGCAAAGAGTTTGTGGATATTCTTATTGTTGCTGTCACGGTTATTGTTGT CGCTATTCCAGGTAAGTGCTGATGTCTACAATCATCTGAGCCCTGCTGACATCCATGTTCTTCGCTAGAGGGTCT CCCACTAGCAGTAACGCTGGCTTTGGCCTTCGCTACTACCCGTATGGTCAAGGAGAACAACCTAGTCCGCGTCCT TCGCGCATGCGAGACAATGGGAAACGCCACGGTCATCTGCTCTGATAAAACAGGCACATTGACACAGAACAAAAT GACCGTTGTGGCCGGAACCTGGGGCTCGAACCAAAACTTCAGCCAGAGAACCGAAGATGAAGATGTGGAAGGTTC AATGACTACTTCGGCCATCTCCCAGAAACTATCAGCTCCCATCAAAGATTTGATTATCAAGAGCATCGCTTTGAA CTCAACTGCGTTTGAACGGGAAAAGGACGGCTCCATCGATTTTGTCGGTAGTAAGACCGAGGTTGCGATGCTTCA GTTGGCTAGGGATTATATGGGCATGGATCTTGTCTCGGAGCGTGGCTCCGCTGAGATCACCCAATTGATTCCTTT CGACTCCGACAGGAAGTGCATGGGTGTTGTTTACCGTGTTCCTGGAGCTGGCTACCGACTGCTTGTCAAGGGAGC GTCCGAGTTGATGGTCGGCGTCTGCACCGCAGAAATTGTCAACATTGATATTTCCAAAGAGAGACCCGATGTGGA GCAGCTTTCTGACGAACAAAAGAAAAACCTTCTGGAGATCATCGACAATTATGCCCACAAGTCTCTTCGAACGAT TGGCATAGTCTACAAGGACTTCGCAAGCTGGCCACCGATCGAAGCCAAACATTCTGAGGATCCTTCAGCAAACTT CGAGGATTTCTTCCATGATATGACTTGGGTTGGAGTTGTAGGTATCCAAGACCCTCTTCGCCCCGAAGTCCCATC GGCCATTCGCAAATGTCACTCGGCAGGCGTCCAGGTCAAGATGGTGACTGGTGACAACGTTGCCACTGCCACTGC TATTGCAACTTCTTGCGGAATCAAGACGGAAGATGGATTGGTCATGGAAGGTCCCAAGTTCCGCCAACTCACAAA CGAGGAGATGGATGAAGTGGTTCCGCGCCTGCAAGTGCTGGCACGATCATCCCCCGAAGACAAGCGAATCTTGGT CGAACGTCTCAAGGCCCTCGGTGAAACGGTCGCCGTGACAGGTGATGGTACCAACGACGGACCGGCTTTGCGGAC TGCAGATGTCGGCTTCTCCATGGGTATTGCTGGTACTGAGGTCGCGAAGGAGGCGAGTTCGATTATTCTCCTGGA TGATAATTTCAAGTCCATCATCACAGCGATCGCTTGGGGACGAGCTGTTAATGACGCCGTTGCCAAGTTTTTGCA ATTCCAGGTCACGGTCAATATCACGGCCGTGATCCTCACTTTTGTGTCATCTGTGTACAGCAGCGAGAACACCAG TGTTTTGACAGCTGTGCAGCTGCTCTGGGTGAACCTGATCATGGACACATTCGCCGCTCTCGCCTTGTAAGTTGT CGTGTTTTTCCTCTTATATTTCCCCTGGACCTCTCGCTAATGTTTTGGAAAATCAGAGCCACGGATGCCCCGACT GAAAAGATTCTCGACCGCAAGCCTGTCTCCAAACACGCCTCCCTTTTCACAATGACCATGTGGAAGATGATTCTT GGCCAAGCAGTATACCAGCTAGCCATCACATTCATGCTTTATTTCGCAGGCGAAAAGCTCCTCAACGCCCATCTC AGCTCCGAGCCCGAGATGCGCGCGAAACAACTCTCGACCGTGGTGTTCAACACGTTCGTGTGGATGCAGATCTTC AACGAATTCAACAATCGCCGCCTCGACAACAAGTTCAATATCTTCGAAGGCATGTTCCGCAATTACTGGTTCTTA GGAATCAACGCCATCATGATCGGTGGCCAGGTCATGATCGTCTTCGTGGGCGGCCAGGCATTCAACGTGACTCGC TTGAACGGCACCCTCTGGGGCGTGTGTTTGATCTGTTCTATTGCCTGCTTGCCCTGGGCTATCGTGCTCCGACTT ATCCCAGACTACTATTTCGGGCTTGTTTTCAATGCCGTTGTTGGCGGTATGGCTGTTGTTTTGCGCCCGCTTTCC AAGGGGTGCAAGGTAATCGGTCGAGGCATCAGGTCTTTCTTTAGGCCTGTGAAGCGTTTCACTCGCCGTATTTTC AACAAGCGGAAGTCAGAAGATGAACTCGAGTTGAAACCAAAGTCTACTGATCCTGAAGAAGCTCCTGAGAGACTA CAACTGAACACGCAAAAGCCCTCTCCTGAGCGTCTGGCCACGCCTACTCCTGTCGTCATTCCCCCTATCACGATT ACTACGTCTCCTTAG