Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g1908.t1
Gene name
Location	scaffold_02:1140516..1144314
Strand	+
Gene length (bp)	3798
Transcript length (bp)	3612
Coding sequence length (bp)	3612
Protein length (aa)	1204

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00072	Response_reg	Response regulator receiver domain	3.7E-20	1076	1194
PF02518	HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	8.1E-06	718	773
PF02518	HATPase_c	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	2.5E-06	771	809
PF00512	HisKA	His Kinase A (phospho-acceptor) domain	8.0E-12	549	611

GO

GO Term	Description	Terminal node
GO:0007165	signal transduction	Yes
GO:0000160	phosphorelay signal transduction system	Yes
GO:0000155	phosphorelay sensor kinase activity	Yes
GO:0003824	catalytic activity	No
GO:0140299	small molecule sensor activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0004672	protein kinase activity	No
GO:0016772	transferase activity, transferring phosphorus-containing groups	No
GO:0008150	biological_process	No
GO:0016740	transferase activity	No
GO:0004673	protein histidine kinase activity	No
GO:0050789	regulation of biological process	No
GO:0016301	kinase activity	No
GO:0065007	biological regulation	No
GO:0003674	molecular_function	No
GO:0035556	intracellular signal transduction	No
GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	No
GO:0050794	regulation of cellular process	No
GO:0009987	cellular process	No
GO:0016773	phosphotransferase activity, alcohol group as acceptor	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 21	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1908.t1 MDYEADRQKREVYRYFQPENPAALNASLFQFDEHLAAIGDFSRVTTPFVPDASASERSFVEGSSPSSPNTTLTSF AQLAALRLNAQRAFITVLNSDSQFILAEATRNTNLKSSRSSVGEGDRLFAGTSTLSDYWNICQETVAIDSDNKDG SYSFLIVNDLQREERFRGLPFVTQEPHSRFYAGTPLTSDSGINLGCLFVLDSEPRQGLSDIEKDTLGKVAELVMD YLLVSRQAAEGRRASRLSRGLHLFVDGNSSFASNAHMSSRSNSSAHSSSPQASPHLRTRQPISPQNDELEFCSAQ SGPGNASRNGDAHPMSSDSNHNEMCAPPSPTESLHSSQQDDSSSEDSSSSNHWLFQRAANLLRQSLDLDGAGGVM FLEASDNSSEYVAAGHSDSAGSTDPAPILALSTRGDPFSYQASSTLSDPAVNLDNRFLKQLTRRYPKGKLWSFHR DGTFSTSEDQSTDDSRKQRKKTKASETSKLNEFFPAASQIMFVPLWNATDSQWFAGCFCWTPRPTRVFSPAVDLS SVFAFGSSIMTEYSRVESVIADRQKGDFISSISHELRSPLHGVLAAAEFFGSTTLDQFQETLLDTINACGRTLLD TMNQVLDFSKIMSLERHKKTFRRGKDPWKPKSSEDTVPRLDTLVLTDVALLTEDVIDSVCLGHSHIQKSAISTNR ATDILSTLPSKSTSNTNKVGHISGVDVVVDIPDNDWMYKVQPGSLRRLIMNILGNALKYTEKGRISVCIEATERS KGRSRRQGLEDMVTLTVSDTGTGLGLSIVRGIVKTLNGKINIRSRQGEGTIVKVSLPLERLVGEESPQSTSEREN SDQNILTASSQPRRASCNGKRAAIWGIDLSHLGENQFWASMARYITDWYGLRLVPLSTNEPIDILFADERDLSTK EIHNFPPELPSLLVFCSETSDYGESRAQWSHLAGTLAILHRPCGPRKLSRGILSCLNTNPTAPTLKPQNPRQGLV FPERPNPTGSALPIRQSNPSLPRNLRSPDAEPPIPMAASGNCIIGLTGRSAFVSTSRTDSSGRTTSGSTDSTNPG SLSTRSSSDGSDHVTPLIGSQSRPRVLVVDDNNINLHLMMTLMNKRKVMVLDKAENGRAAVDAVERMLQGYDLIF MDMSMPVMNGFEATRAIRAIEKERSDCMPATIIALTGLSSTRDEFRALDSGVDLFLVKPVSFRELSRLIDEWEAK LPK*
Coding	>Pro_DTO377G3_2|g1908.t1 ATGGACTACGAGGCAGACCGTCAGAAACGGGAGGTATATCGATATTTCCAACCGGAAAATCCAGCGGCGCTTAAT GCATCACTTTTCCAATTTGATGAGCATCTGGCTGCAATAGGAGATTTTTCAAGAGTCACAACCCCTTTTGTACCC GATGCCTCTGCCTCAGAGAGAAGTTTTGTCGAAGGCAGCTCTCCGTCAAGCCCAAATACAACTTTGACTTCTTTT GCACAACTGGCCGCTCTACGCCTGAACGCGCAGCGTGCTTTTATTACTGTATTGAACAGCGACTCTCAGTTTATA TTGGCTGAAGCCACAAGAAACACCAATCTTAAAAGCTCAAGGTCATCCGTTGGGGAAGGGGATAGGCTCTTCGCT GGGACATCGACATTGTCAGATTATTGGAACATATGCCAGGAGACCGTTGCGATTGACTCAGACAACAAAGATGGA TCGTATTCATTTTTAATCGTCAACGATCTTCAGCGGGAAGAACGATTCAGAGGATTGCCTTTTGTGACACAAGAG CCACACTCTCGGTTTTATGCCGGAACTCCCCTAACTAGTGATAGCGGTATCAACCTGGGCTGTCTGTTTGTGCTG GATTCTGAACCCCGTCAAGGGCTATCCGATATCGAGAAGGATACATTAGGAAAAGTGGCGGAGTTGGTAATGGAC TATTTATTAGTTAGTCGTCAAGCCGCAGAAGGGCGACGGGCCTCACGGCTATCGCGTGGTCTCCATCTTTTCGTC GATGGCAACTCCAGTTTTGCCAGCAACGCTCACATGTCGTCTCGATCAAACAGCTCAGCACATAGTTCGTCTCCG CAGGCATCACCTCACCTCAGAACCCGCCAACCTATAAGCCCCCAAAATGATGAATTGGAATTTTGCTCAGCACAG TCTGGACCAGGAAATGCGTCTCGAAACGGCGATGCACATCCTATGAGCTCGGATTCTAACCATAATGAAATGTGT GCTCCCCCCAGTCCAACGGAATCGTTGCACAGCTCGCAACAGGACGACAGTAGTTCAGAGGATTCCTCGAGCAGC AACCACTGGCTTTTCCAACGTGCTGCGAACCTCTTGCGACAAAGTCTGGACTTGGACGGTGCTGGCGGTGTCATG TTCTTGGAGGCTAGTGACAACTCCTCTGAATATGTCGCAGCTGGTCATAGTGACTCTGCTGGATCCACAGATCCT GCTCCTATTCTTGCGCTGTCCACCAGAGGTGATCCGTTTTCATACCAAGCAAGCTCTACGCTGTCGGATCCAGCT GTCAATCTTGACAACAGATTCCTTAAACAGTTGACGCGTCGCTATCCTAAAGGAAAACTCTGGTCATTTCACCGC GATGGGACGTTCTCAACGTCGGAAGATCAGTCAACAGACGATTCCAGAAAGCAAAGGAAGAAGACCAAGGCTTCA GAGACCAGCAAACTTAATGAGTTCTTCCCTGCTGCATCTCAAATCATGTTTGTCCCACTGTGGAATGCCACAGAT TCCCAGTGGTTCGCTGGGTGCTTTTGTTGGACTCCCCGGCCAACGCGGGTTTTCAGTCCTGCTGTTGATTTGAGT TCAGTGTTTGCCTTCGGCTCTTCTATTATGACCGAATACAGCCGTGTTGAATCGGTCATCGCGGACCGCCAAAAA GGGGATTTTATAAGCAGCATATCCCACGAATTGCGCAGCCCGTTGCATGGTGTTTTAGCTGCAGCTGAGTTTTTC GGGAGTACTACCTTGGACCAGTTCCAAGAAACCCTCCTTGATACGATAAATGCATGTGGTCGAACTCTCTTGGAT ACAATGAACCAAGTTTTAGACTTCAGCAAAATCATGTCATTAGAAAGACACAAAAAAACCTTCAGGCGTGGAAAA GATCCATGGAAACCAAAATCATCTGAAGACACTGTGCCGCGCCTAGATACATTGGTTTTGACAGATGTGGCTCTC TTGACGGAAGATGTCATAGACAGCGTGTGCTTGGGTCATTCCCATATACAGAAGTCAGCCATATCCACCAATCGT GCCACAGATATCTTGTCAACACTGCCTTCCAAATCAACATCAAATACCAACAAAGTTGGTCATATCTCAGGAGTA GACGTCGTTGTTGACATTCCTGATAATGACTGGATGTACAAAGTCCAGCCGGGATCGCTGAGACGCTTAATTATG AATATCCTTGGCAATGCACTAAAGTATACCGAAAAGGGTCGGATCTCTGTTTGCATCGAGGCCACTGAGCGCTCA AAAGGTCGCTCTCGACGCCAAGGTCTCGAAGATATGGTGACATTGACTGTCTCAGACACAGGCACTGGTCTCGGC CTATCAATTGTTCGCGGCATTGTGAAGACTCTTAACGGAAAAATAAATATTCGGAGCCGACAGGGCGAAGGCACT ATTGTCAAAGTGTCGCTTCCTCTTGAACGTCTAGTGGGGGAGGAAAGCCCACAATCAACGTCAGAAAGAGAAAAT TCGGACCAAAATATACTCACGGCATCTTCTCAACCCCGACGTGCCAGCTGTAATGGGAAACGAGCTGCTATCTGG GGAATCGACCTGTCTCATCTTGGCGAGAATCAGTTCTGGGCTTCCATGGCTCGGTATATCACGGATTGGTATGGT CTAAGGCTTGTTCCTCTGTCTACCAATGAGCCTATAGATATTCTGTTTGCGGATGAAAGGGATTTGTCTACAAAA GAAATACACAATTTCCCACCAGAATTGCCAAGTCTACTCGTCTTTTGCAGTGAGACTAGCGATTATGGTGAGTCT AGGGCACAATGGTCGCATCTTGCTGGCACTCTGGCAATCCTACATCGGCCTTGCGGTCCACGGAAACTTTCCCGT GGTATCTTGAGCTGTCTTAATACAAATCCGACAGCCCCTACGTTGAAACCGCAGAATCCCAGGCAAGGCTTAGTA TTTCCAGAGCGACCCAATCCTACAGGCTCGGCTTTGCCAATTAGACAGTCCAATCCCTCATTACCACGAAATCTA CGATCACCAGATGCTGAACCACCAATTCCCATGGCGGCATCGGGCAATTGCATCATTGGTCTTACAGGGCGTAGC GCTTTTGTATCGACATCGCGTACCGACAGCTCTGGCCGCACAACATCCGGGAGTACTGATTCCACCAATCCTGGG TCTTTATCTACTCGGTCTTCATCTGATGGCTCTGATCATGTCACTCCCTTGATTGGGAGCCAAAGCAGGCCTCGG GTCTTGGTAGTAGATGACAACAACATCAACCTTCATCTTATGATGACTCTCATGAACAAACGAAAAGTCATGGTC CTAGATAAAGCCGAAAATGGCAGAGCGGCCGTGGATGCAGTCGAAAGGATGTTGCAGGGATATGACCTTATTTTC ATGGACATGTCTATGCCAGTTATGAACGGATTTGAGGCAACGCGCGCCATTCGTGCAATTGAGAAAGAACGGAGT GACTGTATGCCAGCCACAATAATCGCTTTGACCGGACTCAGCAGTACACGCGATGAGTTCAGGGCCCTGGACTCA GGAGTTGATCTTTTCCTTGTGAAGCCTGTTTCTTTTAGGGAGTTATCCAGGCTTATTGATGAATGGGAGGCCAAA CTGCCGAAATAA
Transcript	>Pro_DTO377G3_2|g1908.t1 ATGGACTACGAGGCAGACCGTCAGAAACGGGAGGTATATCGATATTTCCAACCGGAAAATCCAGCGGCGCTTAAT GCATCACTTTTCCAATTTGATGAGCATCTGGCTGCAATAGGAGATTTTTCAAGAGTCACAACCCCTTTTGTACCC GATGCCTCTGCCTCAGAGAGAAGTTTTGTCGAAGGCAGCTCTCCGTCAAGCCCAAATACAACTTTGACTTCTTTT GCACAACTGGCCGCTCTACGCCTGAACGCGCAGCGTGCTTTTATTACTGTATTGAACAGCGACTCTCAGTTTATA TTGGCTGAAGCCACAAGAAACACCAATCTTAAAAGCTCAAGGTCATCCGTTGGGGAAGGGGATAGGCTCTTCGCT GGGACATCGACATTGTCAGATTATTGGAACATATGCCAGGAGACCGTTGCGATTGACTCAGACAACAAAGATGGA TCGTATTCATTTTTAATCGTCAACGATCTTCAGCGGGAAGAACGATTCAGAGGATTGCCTTTTGTGACACAAGAG CCACACTCTCGGTTTTATGCCGGAACTCCCCTAACTAGTGATAGCGGTATCAACCTGGGCTGTCTGTTTGTGCTG GATTCTGAACCCCGTCAAGGGCTATCCGATATCGAGAAGGATACATTAGGAAAAGTGGCGGAGTTGGTAATGGAC TATTTATTAGTTAGTCGTCAAGCCGCAGAAGGGCGACGGGCCTCACGGCTATCGCGTGGTCTCCATCTTTTCGTC GATGGCAACTCCAGTTTTGCCAGCAACGCTCACATGTCGTCTCGATCAAACAGCTCAGCACATAGTTCGTCTCCG CAGGCATCACCTCACCTCAGAACCCGCCAACCTATAAGCCCCCAAAATGATGAATTGGAATTTTGCTCAGCACAG TCTGGACCAGGAAATGCGTCTCGAAACGGCGATGCACATCCTATGAGCTCGGATTCTAACCATAATGAAATGTGT GCTCCCCCCAGTCCAACGGAATCGTTGCACAGCTCGCAACAGGACGACAGTAGTTCAGAGGATTCCTCGAGCAGC AACCACTGGCTTTTCCAACGTGCTGCGAACCTCTTGCGACAAAGTCTGGACTTGGACGGTGCTGGCGGTGTCATG TTCTTGGAGGCTAGTGACAACTCCTCTGAATATGTCGCAGCTGGTCATAGTGACTCTGCTGGATCCACAGATCCT GCTCCTATTCTTGCGCTGTCCACCAGAGGTGATCCGTTTTCATACCAAGCAAGCTCTACGCTGTCGGATCCAGCT GTCAATCTTGACAACAGATTCCTTAAACAGTTGACGCGTCGCTATCCTAAAGGAAAACTCTGGTCATTTCACCGC GATGGGACGTTCTCAACGTCGGAAGATCAGTCAACAGACGATTCCAGAAAGCAAAGGAAGAAGACCAAGGCTTCA GAGACCAGCAAACTTAATGAGTTCTTCCCTGCTGCATCTCAAATCATGTTTGTCCCACTGTGGAATGCCACAGAT TCCCAGTGGTTCGCTGGGTGCTTTTGTTGGACTCCCCGGCCAACGCGGGTTTTCAGTCCTGCTGTTGATTTGAGT TCAGTGTTTGCCTTCGGCTCTTCTATTATGACCGAATACAGCCGTGTTGAATCGGTCATCGCGGACCGCCAAAAA GGGGATTTTATAAGCAGCATATCCCACGAATTGCGCAGCCCGTTGCATGGTGTTTTAGCTGCAGCTGAGTTTTTC GGGAGTACTACCTTGGACCAGTTCCAAGAAACCCTCCTTGATACGATAAATGCATGTGGTCGAACTCTCTTGGAT ACAATGAACCAAGTTTTAGACTTCAGCAAAATCATGTCATTAGAAAGACACAAAAAAACCTTCAGGCGTGGAAAA GATCCATGGAAACCAAAATCATCTGAAGACACTGTGCCGCGCCTAGATACATTGGTTTTGACAGATGTGGCTCTC TTGACGGAAGATGTCATAGACAGCGTGTGCTTGGGTCATTCCCATATACAGAAGTCAGCCATATCCACCAATCGT GCCACAGATATCTTGTCAACACTGCCTTCCAAATCAACATCAAATACCAACAAAGTTGGTCATATCTCAGGAGTA GACGTCGTTGTTGACATTCCTGATAATGACTGGATGTACAAAGTCCAGCCGGGATCGCTGAGACGCTTAATTATG AATATCCTTGGCAATGCACTAAAGTATACCGAAAAGGGTCGGATCTCTGTTTGCATCGAGGCCACTGAGCGCTCA AAAGGTCGCTCTCGACGCCAAGGTCTCGAAGATATGGTGACATTGACTGTCTCAGACACAGGCACTGGTCTCGGC CTATCAATTGTTCGCGGCATTGTGAAGACTCTTAACGGAAAAATAAATATTCGGAGCCGACAGGGCGAAGGCACT ATTGTCAAAGTGTCGCTTCCTCTTGAACGTCTAGTGGGGGAGGAAAGCCCACAATCAACGTCAGAAAGAGAAAAT TCGGACCAAAATATACTCACGGCATCTTCTCAACCCCGACGTGCCAGCTGTAATGGGAAACGAGCTGCTATCTGG GGAATCGACCTGTCTCATCTTGGCGAGAATCAGTTCTGGGCTTCCATGGCTCGGTATATCACGGATTGGTATGGT CTAAGGCTTGTTCCTCTGTCTACCAATGAGCCTATAGATATTCTGTTTGCGGATGAAAGGGATTTGTCTACAAAA GAAATACACAATTTCCCACCAGAATTGCCAAGTCTACTCGTCTTTTGCAGTGAGACTAGCGATTATGGTGAGTCT AGGGCACAATGGTCGCATCTTGCTGGCACTCTGGCAATCCTACATCGGCCTTGCGGTCCACGGAAACTTTCCCGT GGTATCTTGAGCTGTCTTAATACAAATCCGACAGCCCCTACGTTGAAACCGCAGAATCCCAGGCAAGGCTTAGTA TTTCCAGAGCGACCCAATCCTACAGGCTCGGCTTTGCCAATTAGACAGTCCAATCCCTCATTACCACGAAATCTA CGATCACCAGATGCTGAACCACCAATTCCCATGGCGGCATCGGGCAATTGCATCATTGGTCTTACAGGGCGTAGC GCTTTTGTATCGACATCGCGTACCGACAGCTCTGGCCGCACAACATCCGGGAGTACTGATTCCACCAATCCTGGG TCTTTATCTACTCGGTCTTCATCTGATGGCTCTGATCATGTCACTCCCTTGATTGGGAGCCAAAGCAGGCCTCGG GTCTTGGTAGTAGATGACAACAACATCAACCTTCATCTTATGATGACTCTCATGAACAAACGAAAAGTCATGGTC CTAGATAAAGCCGAAAATGGCAGAGCGGCCGTGGATGCAGTCGAAAGGATGTTGCAGGGATATGACCTTATTTTC ATGGACATGTCTATGCCAGTTATGAACGGATTTGAGGCAACGCGCGCCATTCGTGCAATTGAGAAAGAACGGAGT GACTGTATGCCAGCCACAATAATCGCTTTGACCGGACTCAGCAGTACACGCGATGAGTTCAGGGCCCTGGACTCA GGAGTTGATCTTTTCCTTGTGAAGCCTGTTTCTTTTAGGGAGTTATCCAGGCTTATTGATGAATGGGAGGCCAAA CTGCCGAAATAA
Gene	>Pro_DTO377G3_2|g1908.t1 ATGGACTACGAGGCAGACCGTCAGAAACGGGAGGTATATCGATATTTCCAACCGGAAAATCCAGCGGCGCTTAAT GCATCACTTTTCCAATTTGATGAGCATCTGGCTGCAATAGGAGATTTTTCAAGAGTCACAACCCCTTTTGTACCC GATGCCTCTGCCTCAGAGAGAAGTTTTGTCGAAGGCAGCTCTCCGTCAAGCCCAAATACAACTTTGACTTCTTTT GCACAACTGGCCGCTCTACGCCTGAACGCGCAGCGTGCTTTTATTACGTACATTACTCTCCTGCTCTAGCGTGGA TTCTGATCTGACCCTTTGCAAAGTGTATTGAACAGCGACTCTCAGTTTATATTGGCTGAAGCCACAAGAAACACC AATCTTAAAAGCTCAAGGTCATCCGTTGGGGAAGGGGATAGGCTCTTCGCTGGGACATCGACATTGTCAGATTAT TGGAACATATGCCAGGTAGGTCGATATCTGAAATACTGCGATATTTTACATACTGACGTCTACTCCTTCAAATAG GAGACCGTTGCGATTGACTCAGACAACAAAGATGGATCGTATTCATTTTTAATCGTCAACGATCTTCAGCGGGAA GAACGATTCAGAGGATTGCCTTTTGTGACACAAGAGCCACACTCTCGGTTTTATGCCGGAACTCCCCTAACTAGT GATAGCGGTATCAACCTGGGCTGTCTGTTTGTGCTGGATTCTGAACCCCGTCAAGGGCTATCCGATATCGAGAAG GATACATTAGGAAAAGTGGCGGAGTTGGTAATGGACTATTTATTAGTTAGTCGTCAAGCCGCAGAAGGGCGACGG GCCTCACGGCTATCGCGTGGTCTCCATCTTTTCGTCGATGGCAACTCCAGTTTTGCCAGCAACGCTCACATGTCG TCTCGATCAAACAGCTCAGCACATAGTTCGTCTCCGCAGGCATCACCTCACCTCAGAACCCGCCAACCTATAAGC CCCCAAAATGATGAATTGGAATTTTGCTCAGCACAGTCTGGACCAGGAAATGCGTCTCGAAACGGCGATGCACAT CCTATGAGCTCGGATTCTAACCATAATGAAATGTGTGCTCCCCCCAGTCCAACGGAATCGTTGCACAGCTCGCAA CAGGACGACAGTAGTTCAGAGGATTCCTCGAGCAGCAACCACTGGCTTTTCCAACGTGCTGCGAACCTCTTGCGA CAAAGTCTGGACTTGGACGGTGCTGGCGGTGTCATGTTCTTGGAGGCTAGTGACAACTCCTCTGAATATGTCGCA GCTGGTCATAGTGACTCTGCTGGATCCACAGATCCTGCTCCTATTCTTGCGCTGTCCACCAGAGGTGATCCGTTT TCATACCAAGCAAGCTCTACGCTGTCGGATCCAGCTGTCAATCTTGACAACAGATTCCTTAAACAGTTGACGCGT CGCTATCCTAAAGGAAAACTCTGGTCATTTCACCGCGATGGGACGTTCTCAACGTCGGAAGATCAGTCAACAGAC GATTCCAGAAAGCAAAGGAAGAAGACCAAGGCTTCAGAGACCAGCAAACTTAATGAGTTCTTCCCTGCTGCATCT CAAATCATGTTTGTCCCACTGTGGAATGCCACAGATTCCCAGTGGTTCGCTGGGTGCTTTTGTTGGACTCCCCGG CCAACGCGGGTTTTCAGTCCTGCTGTTGATTTGAGTTCAGTGTTTGCCTTCGGCTCTTCTATTATGACCGAATAC AGCCGTGTTGAATCGGTCATCGCGGACCGCCAAAAAGGGGATTTTATAAGCAGCATATCCCACGAATTGCGCAGC CCGTTGCATGGTGTTTTAGCTGCAGCTGAGTTTTTCGGGAGTACTACCTTGGACCAGTTCCAAGAAACCCTCCTT GATACGATAAATGCATGTGGTCGAACTCTCTTGGATACAATGAACCAAGTTTTAGACTTCAGCAAAATCATGTCA TTAGAAAGACACAAAAAAACCTTCAGGCGTGGAAAAGATCCATGGAAACCAAAATCATCTGAAGACACTGTGCCG CGCCTAGATACATTGGTTTTGACAGATGTGGCTCTCTTGACGGAAGATGTCATAGACAGCGTGTGCTTGGGTCAT TCCCATATACAGAAGTCAGCCATATCCACCAATCGTGCCACAGATATCTTGTCAACACTGCCTTCCAAATCAACA TCAAATACCAACAAAGTTGGTCATATCTCAGGAGTAGACGTCGTTGTTGACATTCCTGATAATGACTGGATGTAC AAAGTCCAGCCGGGATCGCTGAGACGCTTAATTATGAATATCCTTGGCAATGCACTAAAGTATACCGAAAAGGGT CGGATCTCTGTTTGCATCGAGGCCACTGAGCGCTCAAAAGGTCGCTCTCGACGCCAAGGTCTCGAAGATATGGTG ACATTGACTGTCTCAGACACAGGTAAGGGAATCTCGAAGCAATATCTTCAGAAGAACTTATTTATTCCATTCTCA CAAGAGGATCCGCTGTCAGTAGGCACTGGTCTCGGCCTATCAATTGTTCGCGGCATTGTGAAGACTCTTAACGGA AAAATAAATATTCGGAGCCGACAGGGCGAAGGCACTATTGTCAAAGTGTCGCTTCCTCTTGAACGTCTAGTGGGG GAGGAAAGCCCACAATCAACGTCAGAAAGAGAAAATTCGGACCAAAATATACTCACGGCATCTTCTCAACCCCGA CGTGCCAGCTGTAATGGGAAACGAGCTGCTATCTGGGGAATCGACCTGTCTCATCTTGGCGAGAATCAGTTCTGG GCTTCCATGGCTCGGTATATCACGGATTGGTATGGTCTAAGGCTTGTTCCTCTGTCTACCAATGAGCCTATAGAT ATTCTGTTTGCGGATGAAAGGGATTTGTCTACAAAAGAAATACACAATTTCCCACCAGAATTGCCAAGTCTACTC GTCTTTTGCAGTGAGACTAGCGATTATGGTGAGTCTAGGGCACAATGGTCGCATCTTGCTGGCACTCTGGCAATC CTACATCGGCCTTGCGGTCCACGGAAACTTTCCCGTGGTATCTTGAGCTGTCTTAATACAAATCCGACAGCCCCT ACGTTGAAACCGCAGAATCCCAGGCAAGGCTTAGTATTTCCAGAGCGACCCAATCCTACAGGCTCGGCTTTGCCA ATTAGACAGTCCAATCCCTCATTACCACGAAATCTACGATCACCAGATGCTGAACCACCAATTCCCATGGCGGCA TCGGGCAATTGCATCATTGGTCTTACAGGGCGTAGCGCTTTTGTATCGACATCGCGTACCGACAGCTCTGGCCGC ACAACATCCGGGAGTACTGATTCCACCAATCCTGGGTCTTTATCTACTCGGTCTTCATCTGATGGCTCTGATCAT GTCACTCCCTTGATTGGGAGCCAAAGCAGGCCTCGGGTCTTGGTAGTAGATGACAACAACATCAACCTTCATCTT ATGATGACTCTCATGAACAAACGAAAAGTCATGGTCCTAGATAAAGCCGAAAATGGCAGAGCGGCCGTGGATGCA GTCGAAAGGATGTTGCAGGGATATGACCTTATTTTCATGGACATGTCTATGCCAGTTATGAACGGATTTGAGGCA ACGCGCGCCATTCGTGCAATTGAGAAAGAACGGAGTGACTGTATGCCAGCCACAATAATCGCTTTGACCGGACTC AGCAGTACACGCGATGAGTTCAGGGCCCTGGACTCAGGAGTTGATCTTTTCCTTGTGAAGCCTGTTTCTTTTAGG GAGTTATCCAGGCTTATTGATGAATGGGAGGCCAAACTGCCGAAATAA