Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g188.t1
Gene name
Location	scaffold_01:490076..493893
Strand	-
Gene length (bp)	3817
Transcript length (bp)	3606
Coding sequence length (bp)	3606
Protein length (aa)	1202

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF03009	GDPD	Glycerophosphoryl diester phosphodiesterase family	2.4E-71	827	1139
PF12796	Ank_2	Ankyrin repeats (3 copies)	1.3E-06	373	444
PF12796	Ank_2	Ankyrin repeats (3 copies)	2.7E-09	466	521
PF13637	Ank_4	Ankyrin repeats (many copies)	2.9E-08	477	517
PF13637	Ank_4	Ankyrin repeats (many copies)	1.2E-06	536	587
PF03105	SPX	SPX domain	2.3E-09	1	41
PF03105	SPX	SPX domain	1.1E-09	95	145
PF13857	Ank_5	Ankyrin repeats (many copies)	7.2E-08	483	539
PF00023	Ank	Ankyrin repeat	1.7E-02	497	521

GO

GO Term	Description	Terminal node
GO:0005515	protein binding	Yes
GO:0006629	lipid metabolic process	Yes
GO:0008081	phosphoric diester hydrolase activity	Yes
GO:0008150	biological_process	No
GO:0016787	hydrolase activity	No
GO:0044238	primary metabolic process	No
GO:0005488	binding	No
GO:0008152	metabolic process	No
GO:0016788	hydrolase activity, acting on ester bonds	No
GO:0003824	catalytic activity	No
GO:0071704	organic substance metabolic process	No
GO:0003674	molecular_function	No
GO:0042578	phosphoric ester hydrolase activity	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 40	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g188.t1 MKFGRNLPQFTVPEWSGSYIKYKALKKLIKSAAEQIKSGQEPDLAGFFYNLDRNVEDVDHFYNKKYSDFARRLKL LEERYGYSMDGRHALEPEDRHDLREALLDLRYHLRRLQWYGEVNRRGFVKITKKLDKKVGAQAQKRYLETKVDPA PFASNERVFQSQDRINAWMAIITDQSKADDKASDDTSSTHSSLSLKRGPTRPYLNLPTSILTAVDDALRKDDTHV FLELLETLKATADEAGDTVYPRVLRTLIQRSILHRSRAVLNLLLNRVDTLEEDDDINRRNCLHRLVISIGRDQPT TDAEPAASMVLNFPPETTRYITPAAPPTLQPPRPVVKEEHMPQQLGREDSAVIHFQFLLDSLRPDQRESLMAKDL AGRTPLHYAAQYGFKVVCEVIIEHLKEWDMFDVSDGIDGPLWQDNDGWAPLHLSVVGGHPKTTRCLLDAEKQHGP SQGRSIIRKQVSKSSAVLVLATKANFIDIVQLLVDAGVDINYQDEQGETALHVAARFGRDECAQILLDGSDDQKA DTELAENTYSWTPLFIACVDGSLSVAKMLVSAGADVERFDSSGWTAKEHAALRGHLDIARCLAEVSPGPPATEPD FSSSTPNLTGSDSSSPPTQSSLTDRRSNAPGPTSGGPGVRSTEPIKTFGHRYLTDESMILVSLGTMDMRKPLETV SLDRIPMENAHATQLDTSLSMVITASGAHGEPEVIDLPVQDNISTEPIVFHTTDPSKVRLLFDLIPTYAGSKDKI VGRGVALLSSIKPTVGSHRINLKGDSTVPIVAANTLEVIGSVTFNFLIITPFKHPKMSIAGNQTYWRSMSSTMVI GHRGLGKNMAGRNSLQLGENTVESFIAAANLGASYVEFDVQLTKDHVPVIYHDFLVSETGIDAPVHTMTLDQFLE LGIGRYRHSLPGSVKTNGEESELGPRQRSMSVGGSEYNPAELTEKIKHTRDFKKKGFKGNTRGEHIQAPFATLEE LFRKIPKPVGFNIELKYPMLHESEEEEMDTYAVELNSFVDTILTKVYDLGGGRDILFSSFNPDICLLLSFKQPSI PVLFLTDAGASPVGDIRASSLQEAIRFASRWNLLGIVTQAEPLVLCPRLVRIVKESGLVCVSYGTLNNEGKNVDY QVSEGIDAVIVDSVLGITNGLIQRHGKGERTPGTSPNPSAVKDQITNSAKGDVIVPALERVKQTTLSPDMNPPTL L*
Coding	>Pro_DTO377G3_2|g188.t1 ATGAAATTCGGCCGCAATTTGCCGCAGTTCACGGTTCCCGAGTGGAGCGGCTCTTACATCAAGTACAAGGCCCTG AAGAAGCTGATCAAGTCTGCTGCTGAGCAGATCAAATCGGGACAGGAGCCGGATTTGGCTGGTTTCTTCTACAAC CTCGACCGAAATGTTGAAGATGTCGATCATTTCTACAACAAGAAATATTCCGACTTCGCCCGCCGTCTGAAGTTG CTCGAGGAGCGCTATGGCTACTCAATGGATGGTCGCCATGCTCTCGAGCCCGAGGATCGGCATGACCTGCGCGAG GCCCTGCTGGACCTGCGATACCACTTGCGCCGCTTACAATGGTATGGTGAAGTCAATCGACGTGGCTTCGTCAAG ATCACCAAGAAGTTGGACAAGAAGGTTGGTGCGCAGGCCCAGAAGCGCTATCTGGAGACGAAGGTCGATCCCGCC CCGTTCGCCTCCAATGAGCGCGTCTTCCAGTCTCAGGATCGCATCAATGCTTGGATGGCCATCATTACGGACCAG TCCAAGGCGGACGACAAGGCATCCGATGACACGAGCTCCACCCATTCTTCCCTTTCATTGAAGCGTGGCCCAACT AGGCCTTATCTTAATCTGCCTACGAGCATTCTCACTGCTGTGGATGATGCCCTGCGCAAGGATGACACTCATGTC TTCCTTGAACTACTCGAGACTTTGAAGGCCACTGCAGATGAAGCGGGAGACACGGTTTATCCTAGGGTTCTCAGA ACCCTGATCCAGCGCTCTATCCTTCATCGTTCTCGTGCTGTCCTGAATCTTCTCCTGAACCGGGTGGACACCCTA GAAGAGGACGATGACATCAACAGACGTAACTGCCTTCACCGTCTGGTCATTTCCATTGGTCGTGACCAGCCTACG ACTGACGCCGAGCCCGCGGCGTCAATGGTGCTCAACTTCCCTCCGGAGACTACCCGCTATATCACACCCGCGGCA CCTCCGACCCTCCAACCGCCGCGCCCCGTGGTCAAAGAGGAGCACATGCCCCAGCAGCTGGGTCGCGAGGATTCT GCTGTTATTCACTTCCAATTTCTCTTAGACTCGCTGCGCCCTGATCAGCGTGAGTCTTTGATGGCCAAAGACCTT GCTGGACGCACTCCATTGCACTATGCGGCACAGTATGGTTTCAAGGTCGTTTGTGAAGTGATCATTGAGCATCTC AAAGAATGGGACATGTTCGATGTCAGCGATGGGATCGACGGTCCTCTCTGGCAGGACAATGACGGCTGGGCCCCG CTTCATTTGAGTGTTGTGGGTGGCCACCCCAAAACCACCCGGTGTCTCTTGGATGCCGAAAAACAGCATGGTCCC TCGCAGGGGCGGAGCATCATAAGAAAACAGGTCTCGAAGTCTAGTGCAGTATTGGTATTAGCGACCAAGGCCAAC TTCATTGACATTGTCCAGCTTCTGGTGGATGCTGGTGTCGATATCAATTACCAGGATGAACAGGGAGAAACTGCA TTGCACGTTGCCGCCCGATTTGGCCGTGACGAGTGCGCCCAAATTCTGCTGGATGGTAGCGACGACCAGAAGGCA GACACAGAACTAGCTGAAAACACATATAGTTGGACTCCGCTCTTCATTGCCTGTGTGGACGGATCTCTGAGTGTG GCCAAAATGCTGGTTTCCGCTGGTGCAGATGTGGAGCGTTTCGACTCCTCTGGCTGGACGGCTAAGGAGCACGCG GCCCTCAGAGGCCATCTTGACATCGCCCGATGCTTGGCAGAAGTTAGCCCTGGCCCTCCTGCCACTGAGCCTGAT TTTTCATCGTCTACTCCAAACCTCACTGGTTCCGATTCCTCCTCGCCCCCGACTCAGTCGTCCCTCACTGATCGC CGGTCAAATGCGCCTGGCCCAACTTCTGGAGGTCCTGGCGTACGGTCCACTGAACCTATCAAGACTTTTGGACAC AGGTATCTCACCGATGAGAGCATGATCTTGGTCAGTCTGGGAACTATGGACATGCGCAAGCCGCTTGAGACAGTC AGCCTCGACCGCATTCCGATGGAGAATGCACATGCCACCCAGCTAGATACGTCTTTGTCGATGGTGATAACAGCT AGCGGTGCACATGGTGAGCCGGAGGTGATTGACTTGCCTGTGCAGGACAATATCTCAACCGAGCCAATTGTCTTC CACACTACCGATCCTAGCAAGGTGCGTCTGCTTTTCGACCTCATCCCCACCTACGCAGGATCGAAGGATAAGATT GTTGGCCGGGGTGTCGCTCTGCTTTCTAGCATCAAGCCCACTGTCGGGTCGCACCGAATCAACCTCAAAGGTGAT TCCACTGTTCCCATTGTTGCCGCGAATACCCTTGAGGTGATCGGGTCTGTGACGTTCAACTTCCTTATCATCACG CCCTTCAAGCACCCGAAAATGTCTATCGCGGGCAACCAGACCTACTGGCGCTCGATGAGCTCCACCATGGTCATT GGACACCGTGGACTAGGTAAGAATATGGCTGGCCGCAATTCGTTACAGTTGGGCGAGAATACTGTGGAGTCGTTC ATCGCTGCAGCCAACCTGGGCGCCTCATATGTCGAGTTCGATGTACAGCTCACGAAAGACCATGTGCCTGTCATC TACCACGACTTCCTGGTCAGCGAGACAGGTATAGATGCGCCTGTTCATACCATGACACTTGATCAATTCCTCGAG TTAGGCATCGGACGTTACCGTCATTCATTGCCGGGATCTGTCAAAACTAACGGCGAGGAATCTGAGCTTGGCCCG CGCCAGCGCTCAATGTCGGTCGGTGGCTCCGAGTACAACCCGGCCGAATTGACCGAAAAGATCAAGCACACACGC GACTTCAAGAAGAAGGGATTCAAGGGCAACACCCGCGGCGAGCACATTCAGGCACCATTCGCCACACTGGAGGAA TTATTCAGGAAGATCCCGAAACCTGTCGGATTTAATATTGAACTAAAATACCCCATGCTCCACGAGAGCGAGGAG GAAGAAATGGACACATACGCAGTGGAACTGAACTCCTTCGTCGACACCATCTTGACCAAGGTGTATGACCTAGGA GGCGGCCGCGACATACTGTTCTCCAGCTTCAACCCGGACATCTGTCTGCTGCTCTCTTTCAAGCAGCCTTCCATC CCCGTTCTTTTCTTGACTGACGCAGGCGCCTCCCCGGTCGGTGACATCCGTGCCAGCAGCTTGCAGGAGGCTATT CGGTTCGCCTCACGGTGGAATCTCCTTGGAATCGTCACCCAGGCTGAACCACTGGTCCTCTGCCCACGACTAGTC CGAATTGTCAAAGAGTCCGGTCTTGTGTGTGTCTCTTACGGAACACTCAACAATGAGGGCAAGAACGTCGACTAC CAAGTCTCTGAAGGAATCGACGCCGTCATTGTCGACTCTGTGCTCGGCATCACCAACGGTCTCATCCAGCGCCAT GGCAAGGGCGAACGCACACCAGGCACATCGCCTAATCCTTCGGCCGTCAAGGACCAGATCACTAACTCTGCCAAG GGCGATGTCATAGTCCCGGCTCTTGAGCGGGTGAAACAAACTACCCTCTCACCGGATATGAATCCCCCTACCCTT CTTTAA
Transcript	>Pro_DTO377G3_2|g188.t1 ATGAAATTCGGCCGCAATTTGCCGCAGTTCACGGTTCCCGAGTGGAGCGGCTCTTACATCAAGTACAAGGCCCTG AAGAAGCTGATCAAGTCTGCTGCTGAGCAGATCAAATCGGGACAGGAGCCGGATTTGGCTGGTTTCTTCTACAAC CTCGACCGAAATGTTGAAGATGTCGATCATTTCTACAACAAGAAATATTCCGACTTCGCCCGCCGTCTGAAGTTG CTCGAGGAGCGCTATGGCTACTCAATGGATGGTCGCCATGCTCTCGAGCCCGAGGATCGGCATGACCTGCGCGAG GCCCTGCTGGACCTGCGATACCACTTGCGCCGCTTACAATGGTATGGTGAAGTCAATCGACGTGGCTTCGTCAAG ATCACCAAGAAGTTGGACAAGAAGGTTGGTGCGCAGGCCCAGAAGCGCTATCTGGAGACGAAGGTCGATCCCGCC CCGTTCGCCTCCAATGAGCGCGTCTTCCAGTCTCAGGATCGCATCAATGCTTGGATGGCCATCATTACGGACCAG TCCAAGGCGGACGACAAGGCATCCGATGACACGAGCTCCACCCATTCTTCCCTTTCATTGAAGCGTGGCCCAACT AGGCCTTATCTTAATCTGCCTACGAGCATTCTCACTGCTGTGGATGATGCCCTGCGCAAGGATGACACTCATGTC TTCCTTGAACTACTCGAGACTTTGAAGGCCACTGCAGATGAAGCGGGAGACACGGTTTATCCTAGGGTTCTCAGA ACCCTGATCCAGCGCTCTATCCTTCATCGTTCTCGTGCTGTCCTGAATCTTCTCCTGAACCGGGTGGACACCCTA GAAGAGGACGATGACATCAACAGACGTAACTGCCTTCACCGTCTGGTCATTTCCATTGGTCGTGACCAGCCTACG ACTGACGCCGAGCCCGCGGCGTCAATGGTGCTCAACTTCCCTCCGGAGACTACCCGCTATATCACACCCGCGGCA CCTCCGACCCTCCAACCGCCGCGCCCCGTGGTCAAAGAGGAGCACATGCCCCAGCAGCTGGGTCGCGAGGATTCT GCTGTTATTCACTTCCAATTTCTCTTAGACTCGCTGCGCCCTGATCAGCGTGAGTCTTTGATGGCCAAAGACCTT GCTGGACGCACTCCATTGCACTATGCGGCACAGTATGGTTTCAAGGTCGTTTGTGAAGTGATCATTGAGCATCTC AAAGAATGGGACATGTTCGATGTCAGCGATGGGATCGACGGTCCTCTCTGGCAGGACAATGACGGCTGGGCCCCG CTTCATTTGAGTGTTGTGGGTGGCCACCCCAAAACCACCCGGTGTCTCTTGGATGCCGAAAAACAGCATGGTCCC TCGCAGGGGCGGAGCATCATAAGAAAACAGGTCTCGAAGTCTAGTGCAGTATTGGTATTAGCGACCAAGGCCAAC TTCATTGACATTGTCCAGCTTCTGGTGGATGCTGGTGTCGATATCAATTACCAGGATGAACAGGGAGAAACTGCA TTGCACGTTGCCGCCCGATTTGGCCGTGACGAGTGCGCCCAAATTCTGCTGGATGGTAGCGACGACCAGAAGGCA GACACAGAACTAGCTGAAAACACATATAGTTGGACTCCGCTCTTCATTGCCTGTGTGGACGGATCTCTGAGTGTG GCCAAAATGCTGGTTTCCGCTGGTGCAGATGTGGAGCGTTTCGACTCCTCTGGCTGGACGGCTAAGGAGCACGCG GCCCTCAGAGGCCATCTTGACATCGCCCGATGCTTGGCAGAAGTTAGCCCTGGCCCTCCTGCCACTGAGCCTGAT TTTTCATCGTCTACTCCAAACCTCACTGGTTCCGATTCCTCCTCGCCCCCGACTCAGTCGTCCCTCACTGATCGC CGGTCAAATGCGCCTGGCCCAACTTCTGGAGGTCCTGGCGTACGGTCCACTGAACCTATCAAGACTTTTGGACAC AGGTATCTCACCGATGAGAGCATGATCTTGGTCAGTCTGGGAACTATGGACATGCGCAAGCCGCTTGAGACAGTC AGCCTCGACCGCATTCCGATGGAGAATGCACATGCCACCCAGCTAGATACGTCTTTGTCGATGGTGATAACAGCT AGCGGTGCACATGGTGAGCCGGAGGTGATTGACTTGCCTGTGCAGGACAATATCTCAACCGAGCCAATTGTCTTC CACACTACCGATCCTAGCAAGGTGCGTCTGCTTTTCGACCTCATCCCCACCTACGCAGGATCGAAGGATAAGATT GTTGGCCGGGGTGTCGCTCTGCTTTCTAGCATCAAGCCCACTGTCGGGTCGCACCGAATCAACCTCAAAGGTGAT TCCACTGTTCCCATTGTTGCCGCGAATACCCTTGAGGTGATCGGGTCTGTGACGTTCAACTTCCTTATCATCACG CCCTTCAAGCACCCGAAAATGTCTATCGCGGGCAACCAGACCTACTGGCGCTCGATGAGCTCCACCATGGTCATT GGACACCGTGGACTAGGTAAGAATATGGCTGGCCGCAATTCGTTACAGTTGGGCGAGAATACTGTGGAGTCGTTC ATCGCTGCAGCCAACCTGGGCGCCTCATATGTCGAGTTCGATGTACAGCTCACGAAAGACCATGTGCCTGTCATC TACCACGACTTCCTGGTCAGCGAGACAGGTATAGATGCGCCTGTTCATACCATGACACTTGATCAATTCCTCGAG TTAGGCATCGGACGTTACCGTCATTCATTGCCGGGATCTGTCAAAACTAACGGCGAGGAATCTGAGCTTGGCCCG CGCCAGCGCTCAATGTCGGTCGGTGGCTCCGAGTACAACCCGGCCGAATTGACCGAAAAGATCAAGCACACACGC GACTTCAAGAAGAAGGGATTCAAGGGCAACACCCGCGGCGAGCACATTCAGGCACCATTCGCCACACTGGAGGAA TTATTCAGGAAGATCCCGAAACCTGTCGGATTTAATATTGAACTAAAATACCCCATGCTCCACGAGAGCGAGGAG GAAGAAATGGACACATACGCAGTGGAACTGAACTCCTTCGTCGACACCATCTTGACCAAGGTGTATGACCTAGGA GGCGGCCGCGACATACTGTTCTCCAGCTTCAACCCGGACATCTGTCTGCTGCTCTCTTTCAAGCAGCCTTCCATC CCCGTTCTTTTCTTGACTGACGCAGGCGCCTCCCCGGTCGGTGACATCCGTGCCAGCAGCTTGCAGGAGGCTATT CGGTTCGCCTCACGGTGGAATCTCCTTGGAATCGTCACCCAGGCTGAACCACTGGTCCTCTGCCCACGACTAGTC CGAATTGTCAAAGAGTCCGGTCTTGTGTGTGTCTCTTACGGAACACTCAACAATGAGGGCAAGAACGTCGACTAC CAAGTCTCTGAAGGAATCGACGCCGTCATTGTCGACTCTGTGCTCGGCATCACCAACGGTCTCATCCAGCGCCAT GGCAAGGGCGAACGCACACCAGGCACATCGCCTAATCCTTCGGCCGTCAAGGACCAGATCACTAACTCTGCCAAG GGCGATGTCATAGTCCCGGCTCTTGAGCGGGTGAAACAAACTACCCTCTCACCGGATATGAATCCCCCTACCCTT CTTTAA
Gene	>Pro_DTO377G3_2|g188.t1 ATGAAATTCGGCCGCAATTTGCCGCAGTTCACGGTTCCCGAGTGGAGCGGCTCTTACATCAAGTACAAGGCCCTG AAGAAGCTGATCAAGTCTGCTGCTGAGCAGATCAAATCGGGACAGGAGCCGGATTTGGCTGGTAAGTTTAATGCT TCATTTCCTTGAATTTATTATCTTGAACATTTGAGCGCTGTTCTGACCAGGCCGTTTGTGTTGCTGCCTATAGGT TTCTTCTACAACCTCGACCGAAATGTTGAAGATGTCGATCATTTCTACAACAAGAAATATTCCGACTTCGCCCGC CGTCTGAAGTTGCTCGAGGAGCGCTATGGCTACTCAATGGATGGTCGCCATGCTCTCGAGCCCGAGGATCGGCAT GACCTGCGCGAGGCCCTGCTGGACCTGCGATACCACTTGCGCCGCTTACAATGGTATGGTGAAGTCAATCGACGT GGCTTCGTCAAGATCACCAAGAAGTTGGACAAGAAGGTTGGTGCGCAGGCCCAGAAGCGCTATCTGGAGACGAAG GTCGATCCCGCCCCGTTCGCCTCCAATGAGCGCGTCTTCCAGTCTCAGGATCGCATCAATGCTTGGATGGCCATC ATTACGGACCAGTCCAAGGCGGACGACAAGGCATCCGATGACACGAGCTCCACCCATTCTTCCCTTTCATTGAAG CGTGGCCCAACTAGGCCTTATCTTAATCTGCCTACGAGCATTCTCACTGCTGTGGATGATGCCCTGCGCAAGGAT GACACTCATGTCTTCCTTGAACTACTCGAGACTTTGAAGGCCACTGCAGATGAAGCGGGAGACACGGTTTATCCT AGGGTTCTCAGAACCCTGATCCAGCGCTCTATCCTTCATCGTTCTCGTGCTGTCCTGAATCTTCTCCTGAACCGG GTGGACACCCTAGAAGAGGACGATGACATCAACAGACGTAACTGCCTTCACCGTCTGGTCATTTCCATTGGTCGT GACCAGCCTACGACTGACGCCGAGCCCGCGGCGTCAATGGTGCTCAACTTCCCTCCGGAGACTACCCGCTATATC ACACCCGCGGCACCTCCGACCCTCCAACCGCCGCGCCCCGTGGTCAAAGAGGAGCACATGCCCCAGCAGCTGGGT CGCGAGGATTCTGCTGTTATTCACTTCCAATTTCTCTTAGACTCGCTGCGCCCTGATCAGCGTGAGTCTTTGATG GCCAAAGACCTTGCTGGACGCACTCCATTGCACTATGCGGCACAGTATGGTTTCAAGGTCGTTTGTGAAGTGATC ATTGAGCATCTCAAAGAATGGGACATGTTCGATGTCAGCGATGGGATCGACGGTCCTCTCTGGCAGGACAATGAC GGCTGGGCCCCGCTTCATTTGAGTGTTGTGGGTGGCCACCCCAAAACCACCCGGTGTCTCTTGGATGCCGAAAAA CAGCATGGTCCCTCGCAGGGGCGGAGCATCATAAGAAAACAGGTCTCGAAGTCTAGTGCAGTATTGGTATTAGCG ACCAAGGCCAACTTCATTGACATTGTCCAGCTTCTGGTGGATGCTGGTGTCGATATCAATTACCAGGATGAACAG GGAGAAACTGCATTGCACGTTGCCGCCCGATTTGGCCGTGACGAGTGCGCCCAAATTCTGCTGGATGGTAGCGAC GACCAGAAGGCAGACACAGAACTAGCTGAAAACACATATAGTTGGACTCCGCTCTTCATTGCCTGTGTGGACGGA TCTCTGAGTGTGGCCAAAATGCTGGTTTCCGCTGGTGCAGATGTGGAGCGTTTCGACTCCTCTGGCTGGACGGCT AAGGAGCACGCGGCCCTCAGAGGCCATCTTGACATCGCCCGATGCTTGGCAGAAGTTAGCCCTGGCCCTCCTGCC ACTGAGCCTGATTTTTCATCGTCTACTCCAAACCTCACTGGTTCCGATTCCTCCTCGCCCCCGACTCAGTCGTCC CTCACTGATCGCCGGTCAAATGCGCCTGGCCCAACTTCTGGAGGTCCTGGCGTACGGTCCACTGAACCTATCAAG ACTTTTGGACACAGGTATCTCACCGATGAGAGCATGATCTTGGTCAGTCTGGGAACTATGGACATGCGCAAGCCG CTTGAGACAGTCAGCCTCGACCGCATTCCGATGGAGAATGCACATGCCACCCAGCTAGATACGTCTTTGTCGATG GTGATAACAGCTAGCGGTGCACATGGTGAGCCGGAGGTGATTGACTTGCCTGTGCAGGACAATATCTCAACCGAG CCAATTGTCTTCCACACTACCGATCCTAGCAAGGTGCGTCTGCTTTTCGACCTCATCCCCACCTACGCAGGATCG AAGGATAAGATTGTTGGCCGGGGTGTCGCTCTGCTTTCTAGCATCAAGCCCACTGTCGGGTCGCACCGAATCAAC CTCAAAGGTGATTCCACTGTTCCCATTGTTGCCGCGAATACCCTTGAGGTGATCGGGTCTGTGACGTTCAACTTC CTTATCATCACGCCCTTCAAGCACCCGAAAATGTCTATCGCGGGCAACCAGACCTACTGGCGCTCGATGAGCTCC ACCATGGTCATTGGACACCGTGGACTAGGTAAGAATATGGCTGGCCGCAATTCGTTACAGTTGGGCGAGAATACT GTGGAGTCGTTCATCGCTGCAGCCAACCTGGGCGCCTCATATGTCGAGTTCGATGTACAGCTCACGAAAGACCAT GTGCCTGTCATCTACCACGACTTCCTGGTCAGCGAGACAGGTATAGATGCGCCTGTTCATACCATGACACTTGAT CAATTCCTCGAGTTAGGCATCGGACGTTACCGTCATTCATTGCCGGGATCTGTCAAAACTAACGGCGAGGAATCT GAGCTTGGCCCGCGCCAGCGCTCAATGTCGGTCGGTGGCTCCGAGTACAACCCGGCCGAATTGACCGAAAAGATC AAGCACACACGCGACTTCAAGAAGAAGGGATTCAAGGGCAACACCCGCGGCGAGCACATTCAGGCACCATTCGCC ACACTGGAGGAATTATTCAGGAAGATCCCGAAACCTGTCGGATTTAATATTGAACTAAGTGAGTTACTAAAGCTT CCCAAGAACAGCTATTCCGTCGATCTAACCAAGGTCGTCAGAATACCCCATGCTCCACGAGAGCGAGGAGGAAGA AATGGACACATACGCAGTGGAACTGAACTCCTTCGTCGACACCATCTTGACCAAGGTGTATGACCTAGGAGGCGG CCGCGACATACTGTTCTCCAGCTTCAACCCGGACATCTGTCTGCTGCTCTCTTTCAAGCAGCCTTCCATCCCCGT TCTTTTCTTGACTGACGCAGGCGCCTCCCCGGTCGGTGACATCCGTGCCAGCAGCTTGCAGGAGGCTATTCGGTT CGCCTCACGGTGGAATCTCCTTGGAATCGTCACCCAGGCTGAACCACTGGTCCTCTGCCCACGACTAGTCCGAAT TGTCAAAGAGTCCGGTCTTGTGTGTGTCTCTTACGGAACACTCAACAATGAGGGCAAGAACGTCGACGTAAGTTA TGGTCTTTTCACATCCCTAGAAATCTCAAACAACCGTCTTACCACATAATCCCTACAGTACCAAGTCTCTGAAGG AATCGACGCCGTCATTGTCGACTCTGTGCTCGGCATCACCAACGGTCTCATCCAGCGCCATGGCAAGGGCGAACG CACACCAGGCACATCGCCTAATCCTTCGGCCGTCAAGGACCAGATCACTAACTCTGCCAAGGGCGATGTCATAGT CCCGGCTCTTGAGCGGGTGAAACAAACTACCCTCTCACCGGATATGAATCCCCCTACCCTTCTTTAA