Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g1858.t1
Gene name
Location	scaffold_02:1004534..1008133
Strand	-
Gene length (bp)	3599
Transcript length (bp)	3492
Coding sequence length (bp)	3492
Protein length (aa)	1164

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PFAM Domains

(None)

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
Yes	1 - 21	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
3d_25C	Three days - 25 degrees Celsius	2.56	0.90	4.22
5d_25C	Five days - 25 degrees Celsius	1.26	0.28	2.24
7d_25C	Seven days - 25 degrees Celsius	1.55	0.40	2.69
10d_25C	Ten days - 25 degrees Celsius	0.52	0.00	1.07
7d_15C	Seven days - 15 degrees Celsius	1.01	0.16	1.87
7d_30C	Seven days - 30 degrees Celsius	2.72	0.91	4.53

Differential expression

Label1	Label2	Q-value	Significant difference
3d_25C	5d_25C	0.072679	no
3d_25C	7d_25C	0.200477	no
3d_25C	7d_15C	0.028409	yes
3d_25C	7d_30C	0.913541	no
3d_25C	10d_25C	0.002761	yes
5d_25C	7d_25C	0.703224	no
5d_25C	7d_15C	0.717412	no
5d_25C	7d_30C	0.053498	no
5d_25C	10d_25C	0.102850	no
7d_25C	7d_15C	0.375285	no
7d_25C	7d_30C	0.132536	no
7d_25C	10d_25C	0.041798	yes
7d_15C	7d_30C	0.020660	yes
7d_15C	10d_25C	0.243886	no
7d_30C	10d_25C	0.002761	yes

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1858.t1 MKVTSAIVFLSLLASGQATGASWGSEKCYSSPGRSPNKCNDSQQKGFSWTDLAPGSFSSYGGFSFSGFTCGNGFG SSLGKRGTQKCISGTVSKGSSSSSSSSSGSSGSSSHSSSGSGSSSSSSSSSSAPSFSCGSDESGFSVTNFHVATD KDTDLHIIYSMPDGSTCKNTASCNSAGTVVSNDQCGGATSVHFELPDDSEHESCGLGIYSVGFDCTPGSTTTAPV VSSTSAITRVPSEQTSVSSSIVVPSLSVPGSVPGSAVTSSTAVPSLSVPGSTPGSAVSPVTTPAVSTPVQMTTST VFTTSLITITSCAPTVTNCPAGSTVVVTSTIALSTTVCPVTETTATATSSLSVPAVSSPSGVSPVSSSAGIPGVA SGTSVPGSSILPSSAISSTAGETPDVTSATSTPVITTPVQMTTSTVYTTSLVTITSCAPTVTNCPADSTTVVTST IPISTTVCPVTETTTGAVGSTPLSAVPSPSGVSPVSSSAGIPGVPSGTSVPTSSIPASSVSSAPGETPVGTSAAS TPVITTPVQMTTSTVYTTSLVTITSCAPTVTNCPAHSTTVVTSTIPVSTTVRPVTETTTAEVGSTPLSAVPTGVS PVSSSAGSPPASGTSAGTPSAPSVTSAVSSPAGTPLAPGEATTTVVTWETVTTCPVTNTVTSGSSTFVTTSSTIS TVTMTSVSTICTDCSATATSVAGQSTVAPSGTPGVSIIVVSSTGSSDTPGASSLVPSGTSEGSSPVSSSSAEASS PLPTGSDVTSLVPTGVSAETTPAIPQGSTATVVTYVTETTCPVTATVTSGSSTFVTTSSTVSTVTLTSTSNLPSS VAAGSTPAPSETGVAATTAPAVTSANSTPTIPEGATTTVVTYVTETTCPVTNTVTSGSSTFVTTSSTVSTVTLTS VATIATTATAATESQSTSVVPSGVSPVSSPAPSAPCPNTVPQCINTWLSLAPKCTSNSDASCFCPNSEFTSKVIS CIQAWGASKSEIQSALSYFTGICATWVPQNPGIVTAIPSTITLIPTVAPSVPASAAGVTGATVTAPASVVIPITS APALPVTTITYSTYTVTVPQVSFVTNTGSTAGAVPTIGLVPAAPSGTSPANTGVVPAPASATWATSSGYAYASRS ASGVVSPSASPIFNAASSVSVASSLLLASLAAFFGLMM*
Coding	>Pro_DTO377G3_2|g1858.t1 ATGAAGGTCACATCCGCTATTGTGTTTTTATCCCTTCTGGCCTCTGGCCAGGCCACCGGAGCGTCCTGGGGCTCC GAGAAATGCTACTCTAGCCCGGGTAGATCGCCTAACAAGTGTAACGACTCCCAGCAAAAGGGCTTCAGCTGGACT GATCTCGCTCCTGGCTCTTTCTCCAGCTATGGTGGCTTTTCCTTTTCGGGTTTCACTTGCGGCAATGGCTTCGGT TCTAGCCTTGGCAAGCGTGGCACCCAGAAATGTATCTCCGGTACCGTCTCCAAAGGTAGCTCCTCTAGCTCCTCC AGCTCCAGTGGCTCCAGTGGCTCCAGCTCCCACAGCTCCAGTGGCTCCGGCTCCTCTAGCTCTTCTAGCTCCTCC TCGTCGGCTCCGTCGTTCTCCTGTGGCTCGGATGAGAGCGGCTTCTCTGTGACCAACTTCCACGTTGCTACCGAT AAGGATACCGACTTGCACATCATCTACAGCATGCCCGATGGATCGACTTGCAAGAACACCGCTTCCTGCAACTCC GCTGGTACCGTGGTCAGCAACGACCAGTGTGGTGGTGCTACGTCTGTTCACTTCGAGCTGCCCGACGATAGTGAG CATGAGAGCTGCGGTTTGGGCATCTACAGCGTTGGCTTCGACTGCACTCCTGGTTCCACAACCACTGCGCCTGTC GTTTCCAGTACTTCTGCTATTACCAGAGTTCCATCTGAACAGACTTCTGTCTCCAGTTCTATCGTCGTGCCTTCG CTCTCTGTCCCAGGCTCTGTCCCAGGCTCTGCTGTCACCAGCTCTACCGCTGTGCCTTCGCTCTCTGTCCCAGGC TCTACCCCAGGCTCTGCTGTGTCTCCAGTCACCACTCCGGCAGTGAGCACACCTGTTCAGATGACTACCTCGACT GTGTTCACCACTAGTTTGATCACTATCACTAGCTGTGCTCCGACTGTCACCAATTGCCCAGCTGGATCTACCGTT GTGGTAACTTCAACTATCGCTCTTTCCACCACGGTCTGCCCCGTTACTGAGACTACTGCTACCGCTACAAGCTCG CTCTCTGTGCCTGCTGTATCTAGCCCGAGCGGTGTTTCCCCCGTCAGCTCATCGGCTGGTATTCCTGGCGTTGCT AGTGGTACATCCGTTCCTGGATCTTCGATCTTGCCTTCTTCTGCTATTTCCTCTACTGCAGGCGAGACCCCTGAT GTAACTTCTGCCACTTCGACCCCGGTGATCACCACCCCAGTCCAGATGACTACGTCGACCGTGTATACCACCAGT TTGGTTACTATCACTAGCTGTGCCCCGACTGTTACCAATTGTCCAGCAGACTCGACTACAGTGGTGACTTCGACA ATCCCTATTTCAACCACTGTCTGTCCCGTCACTGAGACTACCACAGGTGCCGTCGGCTCCACACCTCTGTCCGCA GTCCCAAGCCCGAGCGGTGTTTCCCCTGTCAGCTCATCGGCTGGTATTCCTGGTGTTCCCAGTGGCACATCCGTC CCTACATCTTCGATTCCGGCCTCTTCTGTTTCATCCGCTCCGGGCGAGACCCCTGTTGGAACTTCAGCCGCTTCA ACCCCGGTGATCACCACTCCGGTCCAGATGACTACCTCAACCGTGTATACCACCAGTTTGGTTACTATCACTAGC TGTGCTCCGACTGTTACCAACTGCCCAGCACACTCGACTACAGTGGTGACTTCGACAATCCCTGTTTCAACCACT GTCCGTCCCGTCACCGAGACTACCACAGCTGAAGTCGGTTCCACACCTCTGTCTGCAGTCCCAACAGGGGTCTCG CCCGTGAGCTCCTCGGCTGGATCACCTCCCGCCAGTGGAACTTCGGCCGGAACCCCCTCGGCTCCCAGCGTGACC TCCGCTGTCTCGTCCCCTGCTGGTACTCCCCTCGCCCCTGGAGAGGCCACTACTACTGTCGTTACTTGGGAGACT GTGACTACTTGCCCGGTGACTAACACGGTTACCTCTGGTAGCTCCACTTTCGTGACTACCTCAAGCACCATTTCA ACCGTTACTATGACTAGTGTCTCTACGATCTGCACCGACTGCTCCGCTACCGCCACCTCCGTTGCTGGTCAGAGC ACTGTTGCCCCGTCTGGTACCCCCGGTGTCTCGATCATTGTCGTTTCCAGCACTGGTTCATCTGATACACCTGGA GCTTCGAGCCTGGTCCCATCTGGAACTTCCGAGGGATCAAGCCCTGTCTCTTCTTCGTCTGCAGAGGCCTCCAGT CCCCTCCCCACCGGCTCCGATGTCACTAGCTTGGTTCCCACCGGCGTGAGCGCTGAGACAACACCTGCTATTCCC CAAGGATCGACTGCCACGGTTGTAACTTATGTAACTGAGACCACCTGTCCTGTGACTGCCACTGTCACTTCTGGG TCGTCGACTTTTGTCACCACATCCAGCACGGTTTCAACTGTTACCTTGACCTCGACTTCCAACCTCCCCAGCTCT GTCGCTGCGGGAAGCACCCCGGCTCCCTCTGAGACAGGTGTCGCTGCCACCACTGCTCCCGCTGTCACCAGTGCC AACTCCACACCCACCATTCCCGAGGGTGCCACTACCACCGTTGTGACTTATGTGACCGAGACCACCTGCCCCGTG ACCAACACCGTCACCTCGGGCTCCTCCACCTTCGTGACCACATCCAGCACAGTTTCCACAGTGACCCTCACCTCC GTCGCAACCATCGCGACTACCGCCACCGCTGCCACCGAGAGTCAATCTACATCCGTAGTCCCCAGCGGCGTGTCC CCAGTATCGAGCCCCGCTCCCTCCGCTCCCTGCCCCAACACCGTACCCCAGTGCATCAACACCTGGCTCTCGCTC GCGCCCAAGTGCACATCCAACAGCGACGCCTCCTGCTTCTGCCCCAACAGCGAGTTCACCAGCAAAGTCATCTCC TGCATCCAAGCCTGGGGTGCCTCGAAGTCCGAGATCCAATCCGCCCTCTCCTACTTCACCGGTATCTGCGCCACC TGGGTCCCCCAGAACCCAGGCATCGTAACCGCCATCCCATCAACAATCACCCTGATCCCGACAGTTGCTCCGTCC GTCCCCGCATCCGCAGCCGGTGTCACCGGCGCCACTGTGACTGCCCCCGCCAGCGTCGTCATCCCCATCACCTCC GCCCCCGCCCTCCCCGTCACCACAATCACCTACTCGACCTACACCGTCACCGTCCCGCAGGTCAGCTTCGTCACA AACACCGGCTCTACGGCCGGTGCTGTGCCGACCATCGGTCTGGTCCCGGCTGCTCCCAGCGGCACTTCCCCGGCA AACACCGGTGTTGTTCCCGCGCCCGCATCCGCAACATGGGCTACTTCGAGCGGGTACGCGTACGCCAGTCGCAGC GCCAGTGGAGTCGTCTCGCCCAGCGCGTCTCCGATCTTCAACGCGGCTTCGAGCGTGTCGGTCGCTTCCAGCCTG CTGTTGGCTTCTCTCGCTGCTTTCTTCGGCTTGATGATGTAG
Transcript	>Pro_DTO377G3_2|g1858.t1 ATGAAGGTCACATCCGCTATTGTGTTTTTATCCCTTCTGGCCTCTGGCCAGGCCACCGGAGCGTCCTGGGGCTCC GAGAAATGCTACTCTAGCCCGGGTAGATCGCCTAACAAGTGTAACGACTCCCAGCAAAAGGGCTTCAGCTGGACT GATCTCGCTCCTGGCTCTTTCTCCAGCTATGGTGGCTTTTCCTTTTCGGGTTTCACTTGCGGCAATGGCTTCGGT TCTAGCCTTGGCAAGCGTGGCACCCAGAAATGTATCTCCGGTACCGTCTCCAAAGGTAGCTCCTCTAGCTCCTCC AGCTCCAGTGGCTCCAGTGGCTCCAGCTCCCACAGCTCCAGTGGCTCCGGCTCCTCTAGCTCTTCTAGCTCCTCC TCGTCGGCTCCGTCGTTCTCCTGTGGCTCGGATGAGAGCGGCTTCTCTGTGACCAACTTCCACGTTGCTACCGAT AAGGATACCGACTTGCACATCATCTACAGCATGCCCGATGGATCGACTTGCAAGAACACCGCTTCCTGCAACTCC GCTGGTACCGTGGTCAGCAACGACCAGTGTGGTGGTGCTACGTCTGTTCACTTCGAGCTGCCCGACGATAGTGAG CATGAGAGCTGCGGTTTGGGCATCTACAGCGTTGGCTTCGACTGCACTCCTGGTTCCACAACCACTGCGCCTGTC GTTTCCAGTACTTCTGCTATTACCAGAGTTCCATCTGAACAGACTTCTGTCTCCAGTTCTATCGTCGTGCCTTCG CTCTCTGTCCCAGGCTCTGTCCCAGGCTCTGCTGTCACCAGCTCTACCGCTGTGCCTTCGCTCTCTGTCCCAGGC TCTACCCCAGGCTCTGCTGTGTCTCCAGTCACCACTCCGGCAGTGAGCACACCTGTTCAGATGACTACCTCGACT GTGTTCACCACTAGTTTGATCACTATCACTAGCTGTGCTCCGACTGTCACCAATTGCCCAGCTGGATCTACCGTT GTGGTAACTTCAACTATCGCTCTTTCCACCACGGTCTGCCCCGTTACTGAGACTACTGCTACCGCTACAAGCTCG CTCTCTGTGCCTGCTGTATCTAGCCCGAGCGGTGTTTCCCCCGTCAGCTCATCGGCTGGTATTCCTGGCGTTGCT AGTGGTACATCCGTTCCTGGATCTTCGATCTTGCCTTCTTCTGCTATTTCCTCTACTGCAGGCGAGACCCCTGAT GTAACTTCTGCCACTTCGACCCCGGTGATCACCACCCCAGTCCAGATGACTACGTCGACCGTGTATACCACCAGT TTGGTTACTATCACTAGCTGTGCCCCGACTGTTACCAATTGTCCAGCAGACTCGACTACAGTGGTGACTTCGACA ATCCCTATTTCAACCACTGTCTGTCCCGTCACTGAGACTACCACAGGTGCCGTCGGCTCCACACCTCTGTCCGCA GTCCCAAGCCCGAGCGGTGTTTCCCCTGTCAGCTCATCGGCTGGTATTCCTGGTGTTCCCAGTGGCACATCCGTC CCTACATCTTCGATTCCGGCCTCTTCTGTTTCATCCGCTCCGGGCGAGACCCCTGTTGGAACTTCAGCCGCTTCA ACCCCGGTGATCACCACTCCGGTCCAGATGACTACCTCAACCGTGTATACCACCAGTTTGGTTACTATCACTAGC TGTGCTCCGACTGTTACCAACTGCCCAGCACACTCGACTACAGTGGTGACTTCGACAATCCCTGTTTCAACCACT GTCCGTCCCGTCACCGAGACTACCACAGCTGAAGTCGGTTCCACACCTCTGTCTGCAGTCCCAACAGGGGTCTCG CCCGTGAGCTCCTCGGCTGGATCACCTCCCGCCAGTGGAACTTCGGCCGGAACCCCCTCGGCTCCCAGCGTGACC TCCGCTGTCTCGTCCCCTGCTGGTACTCCCCTCGCCCCTGGAGAGGCCACTACTACTGTCGTTACTTGGGAGACT GTGACTACTTGCCCGGTGACTAACACGGTTACCTCTGGTAGCTCCACTTTCGTGACTACCTCAAGCACCATTTCA ACCGTTACTATGACTAGTGTCTCTACGATCTGCACCGACTGCTCCGCTACCGCCACCTCCGTTGCTGGTCAGAGC ACTGTTGCCCCGTCTGGTACCCCCGGTGTCTCGATCATTGTCGTTTCCAGCACTGGTTCATCTGATACACCTGGA GCTTCGAGCCTGGTCCCATCTGGAACTTCCGAGGGATCAAGCCCTGTCTCTTCTTCGTCTGCAGAGGCCTCCAGT CCCCTCCCCACCGGCTCCGATGTCACTAGCTTGGTTCCCACCGGCGTGAGCGCTGAGACAACACCTGCTATTCCC CAAGGATCGACTGCCACGGTTGTAACTTATGTAACTGAGACCACCTGTCCTGTGACTGCCACTGTCACTTCTGGG TCGTCGACTTTTGTCACCACATCCAGCACGGTTTCAACTGTTACCTTGACCTCGACTTCCAACCTCCCCAGCTCT GTCGCTGCGGGAAGCACCCCGGCTCCCTCTGAGACAGGTGTCGCTGCCACCACTGCTCCCGCTGTCACCAGTGCC AACTCCACACCCACCATTCCCGAGGGTGCCACTACCACCGTTGTGACTTATGTGACCGAGACCACCTGCCCCGTG ACCAACACCGTCACCTCGGGCTCCTCCACCTTCGTGACCACATCCAGCACAGTTTCCACAGTGACCCTCACCTCC GTCGCAACCATCGCGACTACCGCCACCGCTGCCACCGAGAGTCAATCTACATCCGTAGTCCCCAGCGGCGTGTCC CCAGTATCGAGCCCCGCTCCCTCCGCTCCCTGCCCCAACACCGTACCCCAGTGCATCAACACCTGGCTCTCGCTC GCGCCCAAGTGCACATCCAACAGCGACGCCTCCTGCTTCTGCCCCAACAGCGAGTTCACCAGCAAAGTCATCTCC TGCATCCAAGCCTGGGGTGCCTCGAAGTCCGAGATCCAATCCGCCCTCTCCTACTTCACCGGTATCTGCGCCACC TGGGTCCCCCAGAACCCAGGCATCGTAACCGCCATCCCATCAACAATCACCCTGATCCCGACAGTTGCTCCGTCC GTCCCCGCATCCGCAGCCGGTGTCACCGGCGCCACTGTGACTGCCCCCGCCAGCGTCGTCATCCCCATCACCTCC GCCCCCGCCCTCCCCGTCACCACAATCACCTACTCGACCTACACCGTCACCGTCCCGCAGGTCAGCTTCGTCACA AACACCGGCTCTACGGCCGGTGCTGTGCCGACCATCGGTCTGGTCCCGGCTGCTCCCAGCGGCACTTCCCCGGCA AACACCGGTGTTGTTCCCGCGCCCGCATCCGCAACATGGGCTACTTCGAGCGGGTACGCGTACGCCAGTCGCAGC GCCAGTGGAGTCGTCTCGCCCAGCGCGTCTCCGATCTTCAACGCGGCTTCGAGCGTGTCGGTCGCTTCCAGCCTG CTGTTGGCTTCTCTCGCTGCTTTCTTCGGCTTGATGATGTAG
Gene	>Pro_DTO377G3_2|g1858.t1 ATGAAGGTCACATCCGCTATTGTGTTTTTATCCCTTCTGGCCTCTGGCCAGGCCACCGGAGCGGTATGCCTCAAC TGATATTTGTCGTCTCTGATATCCATCCTAACTCGAAATTCTTTAGTCCTGGGGCTCCGAGAAATGCTACTCTAG CCCGGGTAGATCGCCTAACAAGTGTAACGACTCCCAGCAAAAGGGCTTCAGCTGGACTGATCTCGCTCCTGGCTC TTTCTCCAGCTATGGTGGCTTTTCCTTTTCGGGTTTCACTTGCGGCAATGGCTTCGGTTCTAGCCTTGGCAAGCG TGGCGTGAGTAATGCATGCCTCTCTTTATCTGCACATACTGACCATGCTATAGACCCAGAAATGTATCTCCGGTA CCGTCTCCAAAGGTAGCTCCTCTAGCTCCTCCAGCTCCAGTGGCTCCAGTGGCTCCAGCTCCCACAGCTCCAGTG GCTCCGGCTCCTCTAGCTCTTCTAGCTCCTCCTCGTCGGCTCCGTCGTTCTCCTGTGGCTCGGATGAGAGCGGCT TCTCTGTGACCAACTTCCACGTTGCTACCGATAAGGATACCGACTTGCACATCATCTACAGCATGCCCGATGGAT CGACTTGCAAGAACACCGCTTCCTGCAACTCCGCTGGTACCGTGGTCAGCAACGACCAGTGTGGTGGTGCTACGT CTGTTCACTTCGAGCTGCCCGACGATAGTGAGCATGAGAGCTGCGGTTTGGGCATCTACAGCGTTGGCTTCGACT GCACTCCTGGTTCCACAACCACTGCGCCTGTCGTTTCCAGTACTTCTGCTATTACCAGAGTTCCATCTGAACAGA CTTCTGTCTCCAGTTCTATCGTCGTGCCTTCGCTCTCTGTCCCAGGCTCTGTCCCAGGCTCTGCTGTCACCAGCT CTACCGCTGTGCCTTCGCTCTCTGTCCCAGGCTCTACCCCAGGCTCTGCTGTGTCTCCAGTCACCACTCCGGCAG TGAGCACACCTGTTCAGATGACTACCTCGACTGTGTTCACCACTAGTTTGATCACTATCACTAGCTGTGCTCCGA CTGTCACCAATTGCCCAGCTGGATCTACCGTTGTGGTAACTTCAACTATCGCTCTTTCCACCACGGTCTGCCCCG TTACTGAGACTACTGCTACCGCTACAAGCTCGCTCTCTGTGCCTGCTGTATCTAGCCCGAGCGGTGTTTCCCCCG TCAGCTCATCGGCTGGTATTCCTGGCGTTGCTAGTGGTACATCCGTTCCTGGATCTTCGATCTTGCCTTCTTCTG CTATTTCCTCTACTGCAGGCGAGACCCCTGATGTAACTTCTGCCACTTCGACCCCGGTGATCACCACCCCAGTCC AGATGACTACGTCGACCGTGTATACCACCAGTTTGGTTACTATCACTAGCTGTGCCCCGACTGTTACCAATTGTC CAGCAGACTCGACTACAGTGGTGACTTCGACAATCCCTATTTCAACCACTGTCTGTCCCGTCACTGAGACTACCA CAGGTGCCGTCGGCTCCACACCTCTGTCCGCAGTCCCAAGCCCGAGCGGTGTTTCCCCTGTCAGCTCATCGGCTG GTATTCCTGGTGTTCCCAGTGGCACATCCGTCCCTACATCTTCGATTCCGGCCTCTTCTGTTTCATCCGCTCCGG GCGAGACCCCTGTTGGAACTTCAGCCGCTTCAACCCCGGTGATCACCACTCCGGTCCAGATGACTACCTCAACCG TGTATACCACCAGTTTGGTTACTATCACTAGCTGTGCTCCGACTGTTACCAACTGCCCAGCACACTCGACTACAG TGGTGACTTCGACAATCCCTGTTTCAACCACTGTCCGTCCCGTCACCGAGACTACCACAGCTGAAGTCGGTTCCA CACCTCTGTCTGCAGTCCCAACAGGGGTCTCGCCCGTGAGCTCCTCGGCTGGATCACCTCCCGCCAGTGGAACTT CGGCCGGAACCCCCTCGGCTCCCAGCGTGACCTCCGCTGTCTCGTCCCCTGCTGGTACTCCCCTCGCCCCTGGAG AGGCCACTACTACTGTCGTTACTTGGGAGACTGTGACTACTTGCCCGGTGACTAACACGGTTACCTCTGGTAGCT CCACTTTCGTGACTACCTCAAGCACCATTTCAACCGTTACTATGACTAGTGTCTCTACGATCTGCACCGACTGCT CCGCTACCGCCACCTCCGTTGCTGGTCAGAGCACTGTTGCCCCGTCTGGTACCCCCGGTGTCTCGATCATTGTCG TTTCCAGCACTGGTTCATCTGATACACCTGGAGCTTCGAGCCTGGTCCCATCTGGAACTTCCGAGGGATCAAGCC CTGTCTCTTCTTCGTCTGCAGAGGCCTCCAGTCCCCTCCCCACCGGCTCCGATGTCACTAGCTTGGTTCCCACCG GCGTGAGCGCTGAGACAACACCTGCTATTCCCCAAGGATCGACTGCCACGGTTGTAACTTATGTAACTGAGACCA CCTGTCCTGTGACTGCCACTGTCACTTCTGGGTCGTCGACTTTTGTCACCACATCCAGCACGGTTTCAACTGTTA CCTTGACCTCGACTTCCAACCTCCCCAGCTCTGTCGCTGCGGGAAGCACCCCGGCTCCCTCTGAGACAGGTGTCG CTGCCACCACTGCTCCCGCTGTCACCAGTGCCAACTCCACACCCACCATTCCCGAGGGTGCCACTACCACCGTTG TGACTTATGTGACCGAGACCACCTGCCCCGTGACCAACACCGTCACCTCGGGCTCCTCCACCTTCGTGACCACAT CCAGCACAGTTTCCACAGTGACCCTCACCTCCGTCGCAACCATCGCGACTACCGCCACCGCTGCCACCGAGAGTC AATCTACATCCGTAGTCCCCAGCGGCGTGTCCCCAGTATCGAGCCCCGCTCCCTCCGCTCCCTGCCCCAACACCG TACCCCAGTGCATCAACACCTGGCTCTCGCTCGCGCCCAAGTGCACATCCAACAGCGACGCCTCCTGCTTCTGCC CCAACAGCGAGTTCACCAGCAAAGTCATCTCCTGCATCCAAGCCTGGGGTGCCTCGAAGTCCGAGATCCAATCCG CCCTCTCCTACTTCACCGGTATCTGCGCCACCTGGGTCCCCCAGAACCCAGGCATCGTAACCGCCATCCCATCAA CAATCACCCTGATCCCGACAGTTGCTCCGTCCGTCCCCGCATCCGCAGCCGGTGTCACCGGCGCCACTGTGACTG CCCCCGCCAGCGTCGTCATCCCCATCACCTCCGCCCCCGCCCTCCCCGTCACCACAATCACCTACTCGACCTACA CCGTCACCGTCCCGCAGGTCAGCTTCGTCACAAACACCGGCTCTACGGCCGGTGCTGTGCCGACCATCGGTCTGG TCCCGGCTGCTCCCAGCGGCACTTCCCCGGCAAACACCGGTGTTGTTCCCGCGCCCGCATCCGCAACATGGGCTA CTTCGAGCGGGTACGCGTACGCCAGTCGCAGCGCCAGTGGAGTCGTCTCGCCCAGCGCGTCTCCGATCTTCAACG CGGCTTCGAGCGTGTCGGTCGCTTCCAGCCTGCTGTTGGCTTCTCTCGCTGCTTTCTTCGGCTTGATGATGTAG