Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g1810.t1
Gene name
Location	scaffold_02:891529..895758
Strand	-
Gene length (bp)	4229
Transcript length (bp)	3942
Coding sequence length (bp)	3942
Protein length (aa)	1314

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00122	E1-E2_ATPase	E1-E2 ATPase	1.6E-17	273	494
PF00702	Hydrolase	haloacid dehalogenase-like hydrolase	4.4E-07	512	772

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.5

Transmembrane Domains

Domain #	Start	End	Length
1	36	58	22
2	73	90	17
3	218	235	17
4	239	258	19
5	429	448	19

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1810.t1 MIARRAANPLEPKIIATMAKLVDDPQIHTASLHNPIPWQLHTYVWPFIIIWPVFFAFYLSPERYDTYIQGQEWTF VFAGSIITIQSLFWLMTKWNIDINTLFTTIRAKSIDTARLIKVVPITNAGSAEICKLINENTGTKKTLSFLFQKR RFLFYPETRTFAPLSYVLDAEPKPALETFQLSEGFTSKAEIDRVYNHYGDNTFDIPVPGFLELFQEHAVAPFFVF QIFCVGLWMLDEYWYYSLFTLFMLVMFESTVVWQRQRTLSEFRGMSIKPYDVWVYRERKWQEITSDKLLPGDLMS VNRTKEDSGVACDILLVEGSVIVNEAMLSGESTPLLKDSVQLRPGGDLIEPEGLDKLSFVHGGTKVLQVTHPNLT ADSDLKNLSNNVTMPPDNGALGVVVKTGFETSQGSLVRTMIYSTERVSANNVEALLFILFLLIFAIAASWYVWQE GVIQDRKRSKLLLDCVLIITSVVPPELPMELSLAVNTSLAALSKYAIFCTEPFRIPFAGRVDIACFDKTGTLTGE DLVVDGIAGLGLGEAGSKVEADGAQTELANPSAAGPNTTLVLASAHALVKLDEGEVVGDPMEKATLEWLGWTLGN NDTLSSKGNTPVVAGRNVESVQIKRRFQFSSVLKRQSTIATITTNDRKTSKKIKSTFVGVKGAPETINTMLVNTP PNYEETYKHFTRNGARVLALAYKYLSSESELSQGRVNNYVREEIESELIFAGFLVLQCPLKDDAIKSVRMLNESS HRVVMITGDNPLTAVHVARKVEIVDREVLILDAPEHDNSGTRIVWRTIDDKLNIDVDPTKPLDPEILKTKDICIT GYALAKFKGQQALPVLLRHTWVYARVSPKQKEDILLGLKDAGYTTLMCGDGTNDVGALKQAHVGVALLNGSPDDL TKIAEHYRTTKMKELYEKQVSMMQRFNQPAPPVPVQIAHLYPPGPSNPNYEKAMERESQRKGAAITAAGGTPEAI PTITSPGAQALQLSNLTPQQQKQQKAQAAAAGLADKLTSSLMEQELDESEPPTIKLGDASVAAPFTSKLANVIAI PNILRQGRCTLVATIQMYKILALNCLISAYSLSVIYLEGIKFGDGQVTISGMLMSVCFLSISRAKSVEGLSKERP QPNIFNVYIIGSVLGQFAIHIVTLIYLSNYVYKHEPRDSNIDLEGEFEPSLLNSAIYLLQLIQQISTFSINYQGR PFRESIRENKGMYWGLIAASGVAFSCATEFIPELNEKLRLVPFTNEFKVTLTVLMIFDYGGCWLIENVLKHLFSD FRPKDIALRRPDQLKREADRKLQEQVEAEAQKELQIKN*
Coding	>Pro_DTO377G3_2|g1810.t1 ATGATAGCGCGTCGAGCGGCGAATCCTCTGGAACCAAAAATTATTGCCACCATGGCAAAGCTCGTGGACGATCCT CAGATCCATACTGCTTCGTTGCATAACCCGATCCCTTGGCAATTACACACATACGTCTGGCCTTTCATAATCATC TGGCCCGTGTTCTTCGCCTTCTACCTCTCCCCCGAGCGTTATGATACATACATTCAGGGACAGGAATGGACCTTC GTGTTCGCGGGGTCTATCATCACAATCCAGTCGCTCTTTTGGTTGATGACCAAGTGGAACATTGATATCAACACT CTATTCACTACCATTCGAGCCAAGTCCATCGATACTGCCCGGCTTATCAAAGTGGTTCCCATCACTAACGCTGGC TCTGCCGAGATCTGCAAATTGATTAATGAGAACACCGGCACGAAGAAGACACTTTCGTTCCTCTTCCAGAAGCGC CGCTTTCTCTTTTACCCTGAGACTCGCACCTTCGCACCCTTGTCTTATGTCCTTGACGCCGAACCAAAGCCCGCC CTCGAGACTTTCCAGCTGAGCGAGGGCTTCACGTCGAAGGCCGAGATTGACCGCGTCTACAACCACTATGGCGAT AACACCTTTGATATCCCGGTTCCCGGTTTCCTTGAACTCTTCCAGGAGCATGCTGTCGCGCCGTTCTTCGTCTTC CAGATTTTCTGTGTTGGATTGTGGATGTTGGATGAATATTGGTACTACTCGCTCTTCACGCTTTTCATGCTCGTT ATGTTTGAGAGTACGGTTGTGTGGCAGCGCCAGAGGACCTTGAGCGAGTTCCGTGGAATGAGCATTAAGCCTTAC GATGTCTGGGTGTATCGTGAACGGAAATGGCAAGAGATCACTAGTGATAAGCTTCTTCCCGGTGACCTCATGTCA GTGAACCGCACCAAGGAGGACAGCGGTGTTGCGTGTGATATTCTTCTGGTCGAAGGCAGTGTCATTGTAAACGAG GCTATGCTTTCTGGCGAGAGCACACCTCTGCTGAAAGACTCTGTCCAGCTCCGTCCTGGCGGTGACTTGATTGAG CCGGAAGGATTGGATAAGCTCTCGTTTGTGCATGGAGGTACCAAGGTCCTTCAAGTTACTCACCCTAATCTCACT GCCGACTCGGACTTGAAGAACTTGTCCAACAACGTTACCATGCCCCCAGACAATGGTGCTTTGGGTGTGGTTGTT AAGACCGGTTTTGAAACTAGCCAGGGTAGCCTCGTCCGAACCATGATCTACTCAACTGAACGTGTCTCTGCCAAC AATGTTGAAGCTCTGTTGTTCATCCTCTTCCTCCTGATTTTCGCAATTGCCGCTTCGTGGTACGTGTGGCAAGAG GGTGTGATCCAGGACCGCAAACGCTCCAAGCTTCTGCTCGACTGTGTCCTCATCATCACTAGTGTTGTTCCTCCC GAATTGCCTATGGAATTGAGCTTGGCCGTAAACACTAGTCTTGCTGCTTTGAGCAAGTATGCCATTTTCTGCACC GAGCCTTTCCGTATCCCTTTCGCTGGTCGTGTTGACATCGCTTGCTTTGACAAGACCGGTACCCTGACTGGAGAG GACCTTGTCGTTGATGGTATTGCTGGACTCGGTTTAGGTGAGGCTGGTTCGAAGGTTGAAGCTGATGGTGCTCAG ACTGAATTGGCCAATCCCTCTGCTGCTGGACCCAACACCACTCTCGTTCTCGCCAGTGCTCACGCATTGGTGAAG CTGGATGAGGGTGAGGTCGTCGGTGACCCTATGGAAAAGGCTACATTGGAATGGCTTGGCTGGACTCTGGGAAAC AACGATACTCTGTCTTCCAAGGGCAACACCCCCGTTGTTGCCGGTCGCAACGTTGAATCTGTTCAAATCAAGAGA AGATTCCAGTTCTCCTCGGTTCTGAAACGCCAGAGTACCATCGCGACCATTACGACCAATGACCGCAAGACTTCC AAGAAGATCAAGTCCACATTCGTGGGTGTCAAGGGTGCCCCAGAGACTATTAACACTATGCTGGTCAACACACCT CCCAACTACGAGGAAACCTACAAGCACTTCACCCGCAATGGTGCCCGTGTGCTGGCTCTTGCCTACAAGTATCTT TCATCTGAATCTGAACTTTCCCAGGGCCGCGTGAACAACTACGTTCGCGAAGAGATCGAATCCGAGCTAATTTTT GCCGGTTTCCTTGTCCTTCAATGTCCCTTGAAGGATGATGCCATTAAATCTGTCCGTATGCTAAATGAGAGCAGC CACCGTGTTGTTATGATCACTGGTGATAACCCATTGACTGCTGTCCATGTCGCCCGCAAGGTTGAGATTGTTGAT CGCGAGGTTCTCATCCTTGATGCCCCCGAGCATGACAACTCTGGAACCAGGATTGTCTGGCGCACCATTGATGAT AAGCTCAATATCGACGTCGACCCCACTAAGCCCCTCGACCCGGAGATCCTGAAGACTAAGGACATCTGTATCACT GGATATGCTCTCGCAAAGTTCAAGGGCCAGCAGGCTCTACCTGTTCTGCTCCGTCACACCTGGGTTTATGCTCGT GTGTCTCCTAAGCAAAAGGAAGACATCCTTCTTGGTCTTAAGGACGCTGGATACACCACTCTGATGTGCGGTGAT GGCACCAACGATGTTGGCGCTCTGAAGCAGGCTCACGTCGGTGTCGCGCTTCTGAACGGCTCGCCAGACGATTTA ACTAAGATCGCTGAACACTATCGGACCACTAAGATGAAGGAGCTGTACGAGAAGCAGGTCAGCATGATGCAAAGA TTCAACCAGCCTGCCCCTCCAGTCCCTGTTCAAATCGCTCACCTGTATCCCCCTGGTCCTTCCAACCCTAACTAC GAGAAAGCCATGGAGCGGGAGTCGCAGCGCAAGGGTGCCGCGATCACCGCTGCTGGTGGAACCCCCGAGGCTATC CCAACCATCACATCTCCTGGCGCTCAGGCCTTGCAGCTATCGAACTTGACCCCCCAGCAGCAGAAACAGCAGAAG GCTCAGGCCGCCGCAGCTGGACTTGCAGACAAGCTTACGTCTTCTTTGATGGAACAGGAGCTGGATGAAAGCGAA CCTCCGACTATCAAGTTGGGTGATGCATCAGTCGCTGCTCCCTTCACCAGCAAGTTGGCCAACGTCATTGCTATC CCGAATATCCTTCGTCAAGGTCGTTGCACCCTGGTTGCGACTATTCAGATGTACAAGATTCTTGCTTTGAACTGC TTGATCAGTGCGTACAGTCTGAGTGTCATCTACTTGGAGGGTATTAAGTTCGGTGATGGACAGGTCACCATCAGC GGTATGCTGATGAGTGTCTGCTTCCTTTCTATTTCCCGCGCCAAGTCTGTCGAGGGTCTGTCTAAGGAGCGCCCG CAGCCGAATATCTTCAACGTCTACATTATTGGATCTGTTCTTGGACAGTTTGCCATCCACATCGTGACTCTGATC TACCTCTCCAACTATGTCTATAAGCACGAGCCGAGAGATTCCAATATTGATCTCGAGGGCGAGTTCGAGCCTTCC CTCCTGAACAGTGCCATCTACCTTTTGCAGTTGATCCAGCAAATCTCCACTTTCTCGATCAACTACCAAGGCCGT CCTTTCCGCGAGTCAATCCGCGAGAACAAGGGCATGTACTGGGGCCTCATCGCCGCCTCGGGTGTTGCATTCTCG TGCGCCACCGAATTCATTCCTGAGCTGAATGAGAAGCTGCGCCTTGTCCCCTTCACCAATGAGTTCAAGGTGACT CTGACCGTGCTGATGATCTTCGACTACGGTGGCTGCTGGTTGATTGAGAACGTTCTCAAGCACCTGTTCAGTGAC TTCCGTCCTAAGGACATTGCTCTTCGTCGTCCTGACCAGCTTAAGCGCGAGGCGGACCGTAAGTTGCAAGAACAA GTGGAGGCAGAGGCTCAGAAGGAGCTGCAAATAAAGAACTAG
Transcript	>Pro_DTO377G3_2|g1810.t1 ATGATAGCGCGTCGAGCGGCGAATCCTCTGGAACCAAAAATTATTGCCACCATGGCAAAGCTCGTGGACGATCCT CAGATCCATACTGCTTCGTTGCATAACCCGATCCCTTGGCAATTACACACATACGTCTGGCCTTTCATAATCATC TGGCCCGTGTTCTTCGCCTTCTACCTCTCCCCCGAGCGTTATGATACATACATTCAGGGACAGGAATGGACCTTC GTGTTCGCGGGGTCTATCATCACAATCCAGTCGCTCTTTTGGTTGATGACCAAGTGGAACATTGATATCAACACT CTATTCACTACCATTCGAGCCAAGTCCATCGATACTGCCCGGCTTATCAAAGTGGTTCCCATCACTAACGCTGGC TCTGCCGAGATCTGCAAATTGATTAATGAGAACACCGGCACGAAGAAGACACTTTCGTTCCTCTTCCAGAAGCGC CGCTTTCTCTTTTACCCTGAGACTCGCACCTTCGCACCCTTGTCTTATGTCCTTGACGCCGAACCAAAGCCCGCC CTCGAGACTTTCCAGCTGAGCGAGGGCTTCACGTCGAAGGCCGAGATTGACCGCGTCTACAACCACTATGGCGAT AACACCTTTGATATCCCGGTTCCCGGTTTCCTTGAACTCTTCCAGGAGCATGCTGTCGCGCCGTTCTTCGTCTTC CAGATTTTCTGTGTTGGATTGTGGATGTTGGATGAATATTGGTACTACTCGCTCTTCACGCTTTTCATGCTCGTT ATGTTTGAGAGTACGGTTGTGTGGCAGCGCCAGAGGACCTTGAGCGAGTTCCGTGGAATGAGCATTAAGCCTTAC GATGTCTGGGTGTATCGTGAACGGAAATGGCAAGAGATCACTAGTGATAAGCTTCTTCCCGGTGACCTCATGTCA GTGAACCGCACCAAGGAGGACAGCGGTGTTGCGTGTGATATTCTTCTGGTCGAAGGCAGTGTCATTGTAAACGAG GCTATGCTTTCTGGCGAGAGCACACCTCTGCTGAAAGACTCTGTCCAGCTCCGTCCTGGCGGTGACTTGATTGAG CCGGAAGGATTGGATAAGCTCTCGTTTGTGCATGGAGGTACCAAGGTCCTTCAAGTTACTCACCCTAATCTCACT GCCGACTCGGACTTGAAGAACTTGTCCAACAACGTTACCATGCCCCCAGACAATGGTGCTTTGGGTGTGGTTGTT AAGACCGGTTTTGAAACTAGCCAGGGTAGCCTCGTCCGAACCATGATCTACTCAACTGAACGTGTCTCTGCCAAC AATGTTGAAGCTCTGTTGTTCATCCTCTTCCTCCTGATTTTCGCAATTGCCGCTTCGTGGTACGTGTGGCAAGAG GGTGTGATCCAGGACCGCAAACGCTCCAAGCTTCTGCTCGACTGTGTCCTCATCATCACTAGTGTTGTTCCTCCC GAATTGCCTATGGAATTGAGCTTGGCCGTAAACACTAGTCTTGCTGCTTTGAGCAAGTATGCCATTTTCTGCACC GAGCCTTTCCGTATCCCTTTCGCTGGTCGTGTTGACATCGCTTGCTTTGACAAGACCGGTACCCTGACTGGAGAG GACCTTGTCGTTGATGGTATTGCTGGACTCGGTTTAGGTGAGGCTGGTTCGAAGGTTGAAGCTGATGGTGCTCAG ACTGAATTGGCCAATCCCTCTGCTGCTGGACCCAACACCACTCTCGTTCTCGCCAGTGCTCACGCATTGGTGAAG CTGGATGAGGGTGAGGTCGTCGGTGACCCTATGGAAAAGGCTACATTGGAATGGCTTGGCTGGACTCTGGGAAAC AACGATACTCTGTCTTCCAAGGGCAACACCCCCGTTGTTGCCGGTCGCAACGTTGAATCTGTTCAAATCAAGAGA AGATTCCAGTTCTCCTCGGTTCTGAAACGCCAGAGTACCATCGCGACCATTACGACCAATGACCGCAAGACTTCC AAGAAGATCAAGTCCACATTCGTGGGTGTCAAGGGTGCCCCAGAGACTATTAACACTATGCTGGTCAACACACCT CCCAACTACGAGGAAACCTACAAGCACTTCACCCGCAATGGTGCCCGTGTGCTGGCTCTTGCCTACAAGTATCTT TCATCTGAATCTGAACTTTCCCAGGGCCGCGTGAACAACTACGTTCGCGAAGAGATCGAATCCGAGCTAATTTTT GCCGGTTTCCTTGTCCTTCAATGTCCCTTGAAGGATGATGCCATTAAATCTGTCCGTATGCTAAATGAGAGCAGC CACCGTGTTGTTATGATCACTGGTGATAACCCATTGACTGCTGTCCATGTCGCCCGCAAGGTTGAGATTGTTGAT CGCGAGGTTCTCATCCTTGATGCCCCCGAGCATGACAACTCTGGAACCAGGATTGTCTGGCGCACCATTGATGAT AAGCTCAATATCGACGTCGACCCCACTAAGCCCCTCGACCCGGAGATCCTGAAGACTAAGGACATCTGTATCACT GGATATGCTCTCGCAAAGTTCAAGGGCCAGCAGGCTCTACCTGTTCTGCTCCGTCACACCTGGGTTTATGCTCGT GTGTCTCCTAAGCAAAAGGAAGACATCCTTCTTGGTCTTAAGGACGCTGGATACACCACTCTGATGTGCGGTGAT GGCACCAACGATGTTGGCGCTCTGAAGCAGGCTCACGTCGGTGTCGCGCTTCTGAACGGCTCGCCAGACGATTTA ACTAAGATCGCTGAACACTATCGGACCACTAAGATGAAGGAGCTGTACGAGAAGCAGGTCAGCATGATGCAAAGA TTCAACCAGCCTGCCCCTCCAGTCCCTGTTCAAATCGCTCACCTGTATCCCCCTGGTCCTTCCAACCCTAACTAC GAGAAAGCCATGGAGCGGGAGTCGCAGCGCAAGGGTGCCGCGATCACCGCTGCTGGTGGAACCCCCGAGGCTATC CCAACCATCACATCTCCTGGCGCTCAGGCCTTGCAGCTATCGAACTTGACCCCCCAGCAGCAGAAACAGCAGAAG GCTCAGGCCGCCGCAGCTGGACTTGCAGACAAGCTTACGTCTTCTTTGATGGAACAGGAGCTGGATGAAAGCGAA CCTCCGACTATCAAGTTGGGTGATGCATCAGTCGCTGCTCCCTTCACCAGCAAGTTGGCCAACGTCATTGCTATC CCGAATATCCTTCGTCAAGGTCGTTGCACCCTGGTTGCGACTATTCAGATGTACAAGATTCTTGCTTTGAACTGC TTGATCAGTGCGTACAGTCTGAGTGTCATCTACTTGGAGGGTATTAAGTTCGGTGATGGACAGGTCACCATCAGC GGTATGCTGATGAGTGTCTGCTTCCTTTCTATTTCCCGCGCCAAGTCTGTCGAGGGTCTGTCTAAGGAGCGCCCG CAGCCGAATATCTTCAACGTCTACATTATTGGATCTGTTCTTGGACAGTTTGCCATCCACATCGTGACTCTGATC TACCTCTCCAACTATGTCTATAAGCACGAGCCGAGAGATTCCAATATTGATCTCGAGGGCGAGTTCGAGCCTTCC CTCCTGAACAGTGCCATCTACCTTTTGCAGTTGATCCAGCAAATCTCCACTTTCTCGATCAACTACCAAGGCCGT CCTTTCCGCGAGTCAATCCGCGAGAACAAGGGCATGTACTGGGGCCTCATCGCCGCCTCGGGTGTTGCATTCTCG TGCGCCACCGAATTCATTCCTGAGCTGAATGAGAAGCTGCGCCTTGTCCCCTTCACCAATGAGTTCAAGGTGACT CTGACCGTGCTGATGATCTTCGACTACGGTGGCTGCTGGTTGATTGAGAACGTTCTCAAGCACCTGTTCAGTGAC TTCCGTCCTAAGGACATTGCTCTTCGTCGTCCTGACCAGCTTAAGCGCGAGGCGGACCGTAAGTTGCAAGAACAA GTGGAGGCAGAGGCTCAGAAGGAGCTGCAAATAAAGAACTAG
Gene	>Pro_DTO377G3_2|g1810.t1 ATGATAGCGCGTCGAGCGGCGAATCCTCTGGAACCAAAAATTGTAAGGTGGAAGGTGGCTTCATCAACAAATCTG GGCATTCCCTCGATTGGATACTATCATTGCTTTCGGAATTCGTATGAGTCTTTAATTTTCAGCTTGTTAGACTCT GACCGCGGTCACTAGATTGCCACCATGTACGTTACCAGAAGCTTCCCCCGATTCTTTGCGGCTACAGCTAACAGT ATACAGGGCAAAGCTCGTGGACGATCCTCAGATCCATACTGCTTCGTTGCATAACCCGATCCCTTGGCAATTACA CACATACGTCTGGCCTTTCATAATCATCTGGCCCGTGTTCTTCGCCTTCTACCTCTCCCCCGAGCGTTATGATAC ATACATTCAGGGACAGGAATGGACCTTCGTGTTCGCGGGGTCTATCATCACAATCCAGTCGCTCTTTTGGTTGAT GACCAAGTGGAACATTGATATCAACACTCTATTCACTACCATTCGAGCCAAGTCCATCGATACTGCCCGGCTTAT CAAAGTGGTTCCCATCACTAACGCTGGCTCTGCCGAGATCTGCAAATTGATTAATGAGAACACCGGCACGAAGAA GACACTTTCGTTCCTCTTCCAGAAGCGCCGCTTTCTCTTTTACCCTGAGACTCGCACCTTCGCACCCTTGTCTTA TGTCCTTGACGCCGAACCAAAGCCCGCCCTCGAGACTTTCCAGCTGAGCGAGGGCTTCACGTCGAAGGCCGAGAT TGACCGCGTCTACAACCACTATGGCGATAACACCTTTGATATCCCGGTTCCCGGTTTCCTTGAACTCTTCCAGGA GCATGCTGTCGCGCCGTTCTTCGTCTTCCAGATTTTCTGTGTTGGATTGTGGATGTTGGATGAATATTGGTACTA CTCGCTCTTCACGCTTTTCATGCTCGTTATGTTTGAGAGTACGGTTGTGTGGCAGCGCCAGAGGACCTTGAGCGA GTTCCGTGGAATGAGCATTAAGCCTTACGATGTCTGGGTGTATCGTGAACGGAAATGGCAAGAGATCACTAGTGA TAAGCTTCTTCCCGGTGACCTCATGTCAGTGAACCGCACCAAGGAGGACAGCGGTGTTGCGTGTGATATTCTTCT GGTCGAAGGCAGTGTCATTGTAAACGAGGCTATGCTTTCTGGCGAGAGCACACCTCTGCTGAAAGACTCTGTCCA GCTCCGTCCTGGCGGTGACTTGATTGAGCCGGAAGGATTGGATAAGCTCTCGTTTGTGCATGGAGGTACCAAGGT CCTTCAAGTTACTCACCCTAATCTCACTGCCGACTCGGACTTGAAGAACTTGTCCAACAACGTTACCATGCCCCC AGACAATGGTGCTTTGGGTGTGGTTGTTAAGACCGGTTTTGAAACTAGCCAGGGTAGCCTCGTCCGAACCATGAT CTACTCAACTGAACGTGTCTCTGCCAACAATGTTGAAGCTCTGTTGTTCATCCTCTTCCTCCTGATTTTCGCAAT TGCCGCTTCGTGGTACGTGTGGCAAGAGGGTGTGATCCAGGACCGCAAACGCTCCAAGCTTCTGCTCGACTGTGT CCTCATCATCACTAGTGTTGTTCCTCCCGAATTGCCTATGGAATTGAGCTTGGCCGTAAACACTAGTCTTGCTGC TTTGAGCAAGTATGCCATTTTCTGCACCGAGCCTTTCCGTATCCCTTTCGCTGGTCGTGTTGACATCGCTTGCTT TGACAAGACCGGTACCCTGACTGGAGAGGACCTTGTCGTTGATGGTATTGCTGGACTCGGTTTAGGTGAGGCTGG TTCGAAGGTTGAAGCTGATGGTGCTCAGACTGAATTGGCCAATCCCTCTGCTGCTGGACCCAACACCACTCTCGT TCTCGCCAGTGCTCACGCATTGGTGAAGCTGGATGAGGGTGAGGTCGTCGGTGACCCTATGGAAAAGGCTACATT GGAATGGCTTGGCTGGACTCTGGGAAACAACGATACTCTGTCTTCCAAGGGCAACACCCCCGTTGTTGCCGGTCG CAACGTTGAATCTGTTCAAATCAAGAGAAGATTCCAGTTCTCCTCGGTTCTGAAACGCCAGAGTACCATCGCGAC CATTACGACCAATGACCGCAAGACTTCCAAGAAGATCAAGTCCACATTCGTGGGTGTCAAGGGTGCCCCAGAGAC TATTAACACTATGCTGGTCAACACACCTCCCAACTACGAGGAAACCTACAAGCACTTCACCCGCAATGGTGCCCG TGTGCTGGCTCTTGCCTACAAGTATCTTTCATCTGAATCTGAACTTTCCCAGGGCCGCGTGAACAACTACGTTCG CGAAGAGATCGAATCCGAGCTAATTTTTGCCGGTTTCCTTGTCCTTCAATGTCCCTTGAAGGATGATGCCATTAA ATCTGTCCGTATGCTAAATGAGAGCAGCCACCGTGTTGTTATGATCACTGGTGATAACCCATTGACTGCTGTCCA TGTCGCCCGCAAGGTTGAGATTGTTGATCGCGAGGTTCTCATCCTTGATGCCCCCGAGCATGACAACTCTGGAAC CAGGATTGTCTGGCGCACCATTGATGATAAGCTCAATATCGACGTCGACCCCACTAAGCCCCTCGACCCGGAGAT CCTGAAGACTAAGGACATCTGTATCACTGGATATGCTCTCGCAAAGTTCAAGGGCCAGCAGGCTCTACCTGTTCT GCTCCGTCACACCTGGGTTTATGCTCGTGTGTCTCCTAAGCAAAAGGAAGACATCCTTCTTGGTCTTAAGGACGC TGGATACACCACTCTGATGTGCGGTGATGGCACCAACGATGTTGGCGCTCTGAAGCAGGCTCACGTCGGTGTCGC GCTTCTGAACGGCTCGCCAGACGATTTAACTAAGATCGCTGAACACTATCGGACCACTAAGATGAAGGAGCTGTA CGAGAAGCAGGTCAGCATGATGCAAAGATTCAACCAGCCTGCCCCTCCAGTCCCTGTTCAAATCGCTCACCTGTA TCCCCCTGGTCCTTCCAACCCTAACTACGAGAAAGCCATGGAGCGGGAGTCGCAGCGCAAGGGTGCCGCGATCAC CGCTGCTGGTGGAACCCCCGAGGCTATCCCAACCATCACATCTCCTGGCGCTCAGGCCTTGCAGCTATCGAACTT GACCCCCCAGCAGCAGAAACAGCAGAAGGCTCAGGCCGCCGCAGCTGGACTTGCAGACAAGCTTACGTCTTCTTT GATGGAACAGGAGCTGGATGAAAGCGAACCTCCGACTATCAAGTTGGGTGATGCATCAGTCGCTGCTCCCTTCAC CAGCAAGTTGGCCAACGTCATTGCTATCCCGAATATCCTTCGTCAAGGTCGTTGCACCCTGGTTGCGACTATTCA GATGTACAAGATTCTTGCTTTGAACTGCTTGATCAGTGCGTACAGTCTGAGTGTCATCTACTTGGAGGGTATTAA GTTCGGTGATGGACAGGTCACCATCAGCGGTATGCTGATGAGTGTCTGCTTCCTTTCTATTTCCCGCGCCAAGGT ATGTCATACTTCTCCGCGTTCACAAATTGCTTTGCTAATGTTTTAATGTGAAGTCTGTCGAGGGTCTGTCTAAGG AGCGCCCGCAGCCGAATATCTTCAACGTCTACATTATTGGATCTGTTCTTGGACAGTTTGCCATCCACATCGTGA CTCTGATCTACCTCTCCAACTATGTCTATAAGCACGAGCCGTACGTTGAACCTCCCTCTGATTTGTCCCACCTCA TAGCTAACACAACCGATAGGAGAGATTCCAATATTGATCTCGAGGGCGAGTTCGAGCCTTCCCTCCTGAACAGTG CCATCTACCTTTTGCAGTTGATCCAGCAAATCTCCACTTTCTCGATCAACTACCAAGGCCGTCCTTTCCGCGAGT CAATCCGCGAGAACAAGGGCATGTACTGGGGCCTCATCGCCGCCTCGGGTGTTGCATTCTCGTGCGCCACCGAAT TCATTCCTGAGCTGAATGAGAAGCTGCGCCTTGTCCCCTTCACCAATGAGTTCAAGGTGACTCTGACCGTGCTGA TGATCTTCGACTACGGTGGCTGCTGGTTGATTGAGAACGTTCTCAAGCACCTGTTCAGTGACTTCCGTCCTAAGG ACATTGCTCTTCGTCGTCCTGACCAGCTTAAGCGCGAGGCGGACCGTAAGTTGCAAGAACAAGTGGAGGCAGAGG CTCAGAAGGAGCTGCAAATAAAGAACTAG