Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g1658.t1
Gene name
Location	scaffold_02:535023..538294
Strand	-
Gene length (bp)	3271
Transcript length (bp)	2883
Coding sequence length (bp)	2883
Protein length (aa)	961

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF01432	Peptidase_M3	Peptidase family M3	2.2E-161	220	712

GO

GO Term	Description	Terminal node
GO:0006508	proteolysis	Yes
GO:0004222	metalloendopeptidase activity	Yes
GO:0008152	metabolic process	No
GO:0071704	organic substance metabolic process	No
GO:0016787	hydrolase activity	No
GO:0003824	catalytic activity	No
GO:0003674	molecular_function	No
GO:0008233	peptidase activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0043170	macromolecule metabolic process	No
GO:0006807	nitrogen compound metabolic process	No
GO:0004175	endopeptidase activity	No
GO:1901564	organonitrogen compound metabolic process	No
GO:0019538	protein metabolic process	No
GO:0044238	primary metabolic process	No
GO:0008150	biological_process	No
GO:0008237	metallopeptidase activity	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
3d_25C	Three days - 25 degrees Celsius	80.54	48.94	112.13
5d_25C	Five days - 25 degrees Celsius	67.30	41.13	93.47
7d_25C	Seven days - 25 degrees Celsius	55.94	34.34	77.53
10d_25C	Ten days - 25 degrees Celsius	56.09	34.41	77.77
7d_15C	Seven days - 15 degrees Celsius	84.93	51.53	118.32
7d_30C	Seven days - 30 degrees Celsius	65.42	39.98	90.86

Differential expression

Label1	Label2	Q-value	Significant difference
3d_25C	5d_25C	0.470774	no
3d_25C	7d_25C	0.083660	no
3d_25C	7d_15C	0.864654	no
3d_25C	7d_30C	0.394684	no
3d_25C	10d_25C	0.089476	no
5d_25C	7d_25C	0.453442	no
5d_25C	7d_15C	0.323260	no
5d_25C	7d_30C	0.935771	no
5d_25C	10d_25C	0.463588	no
7d_25C	7d_15C	0.042216	yes
7d_25C	7d_30C	0.544036	no
7d_25C	10d_25C	0.994202	no
7d_15C	7d_30C	0.255646	no
7d_15C	10d_25C	0.045957	yes
7d_30C	10d_25C	0.552682	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1658.t1 MAPAHLRKPPQAPPVFTATPQSLLADAERLIKSSRAIQDKVVAEVKPEAATFAKVVLPLAQDDNQMGLESHILGF YQAVSTDSKLRDASSKAEELMDEFFIEAVMREDVFNLVDAVLRRNEILDPESRRLLEKEHKDFIRNGLGLPDGPH RLRFKEIKKRLSQLSIEFQKNLNEENGGIWFTPEQLAGVPKDLLDGLKKGEDENAGKLWLSFKYPDLFPTMKYAS DPETRRQVMIANENKCNQNVPLFRESIILRDEAARLIGYPNHAAFRIEDKMAKTPETVNKFLGDLRDRLTAGGKK EIQKLLDLKNATDPNADGRYYLWDHRFYDRLMLEKDYSLDHQLIAEWFPLQTTIQGMLKIFEELFGLEFVEIIGE DRAAIAPTGQGNDIVWHEDVQVFSVWNDEDAGSGFVGYLYLDLFPREGKYGHAANFNLQPGFINKDGTRRFPATA LVCNFTKPQPKKPSLLKHDEVVTLFHELGHGIHDLVSRTIYSRFHGTSTVRDFVEAPSQMLENWCWEPSQLRSLS RHYSTLSPEYLASWKEAQGEAATSQPSERIPDDVIANLIRTKHVNDSLFNLRQLHFGIFDMTVHEPKTHADIEAL PLSATYNRLRHEITQMDGPEVQGAGDEWGHGEATFGHLIGGYDAGYYGYLSSQVYSTDMFYTVFKDDPMNKAAGR RYRYQVLEKGGSQDEMKTLTEFLGRAPRTDAFYKDLGLALAVDTDKRTALPFCNSPQLNSSFSRSSHFRTSAYKT TQSLGLNKCIQSPLCITNIRDQSASAQQLQIPDSYQFKSATTTRNISTLPRRGGEGKDKALILPLERKSSTDADA DADIEADLEEEARTTETEPSSRKTRARHVSNHTTLLLATTIPDRRATIIRREDGIEKRILLRCGRCKVVVGYYLD RLHWASTGDRERERGGARDGEEEGEEERPPAVYLLPGAVVETEKLGGEGVGEREWREWVV*
Coding	>Pro_DTO377G3_2|g1658.t1 ATGGCCCCCGCTCACCTCCGGAAGCCACCCCAGGCCCCGCCTGTCTTTACCGCAACCCCGCAGTCACTTCTAGCT GATGCCGAGCGCTTGATCAAGAGCTCGCGAGCCATTCAGGACAAGGTGGTGGCGGAGGTCAAGCCCGAGGCCGCA ACCTTTGCCAAGGTTGTCCTTCCTCTCGCCCAAGATGACAACCAGATGGGACTAGAGTCACACATCCTGGGCTTC TACCAGGCTGTATCAACAGACTCGAAGCTGCGAGATGCTTCTTCCAAGGCCGAAGAGCTGATGGATGAGTTCTTT ATTGAGGCGGTCATGCGTGAGGATGTCTTCAATTTGGTCGATGCCGTACTGCGCCGCAACGAGATTCTCGATCCG GAGTCACGCCGTCTATTGGAGAAGGAACACAAGGACTTCATCCGTAATGGACTCGGCCTGCCCGATGGCCCTCAT CGGCTCCGCTTCAAGGAGATCAAGAAGCGGCTGAGCCAGCTGAGCATTGAATTCCAGAAGAACCTGAACGAGGAG AACGGCGGCATTTGGTTTACCCCGGAGCAGCTGGCTGGTGTGCCCAAGGACCTTCTGGACGGCCTGAAGAAGGGC GAGGACGAGAACGCCGGCAAGCTCTGGCTGTCGTTCAAGTACCCCGACCTCTTCCCCACCATGAAATATGCCAGC GACCCCGAGACTCGCCGGCAAGTCATGATCGCCAATGAGAACAAGTGCAACCAGAATGTGCCGCTATTCCGGGAA TCCATTATACTCCGTGATGAGGCGGCTCGTCTGATCGGCTATCCCAACCACGCTGCCTTTCGTATCGAGGACAAG ATGGCCAAGACCCCAGAGACCGTTAACAAGTTTTTGGGTGATCTTCGGGACAGACTGACCGCTGGCGGGAAGAAG GAGATACAGAAGTTGCTGGATTTGAAGAACGCCACGGACCCCAATGCTGATGGCCGCTACTACCTGTGGGACCAC CGATTCTATGACCGTCTCATGCTAGAAAAGGACTACTCGCTAGACCACCAGCTTATTGCTGAGTGGTTCCCCTTG CAGACAACCATTCAAGGTATGCTGAAGATTTTCGAAGAGCTGTTCGGTCTGGAGTTTGTTGAGATCATTGGTGAG GACCGGGCAGCCATTGCCCCCACTGGCCAGGGCAATGACATTGTCTGGCACGAGGATGTCCAAGTATTCAGTGTG TGGAACGATGAGGACGCGGGCAGTGGGTTCGTTGGATACCTGTACCTGGACCTGTTCCCTCGCGAGGGCAAATAT GGCCATGCAGCCAACTTCAACCTGCAGCCGGGCTTCATTAATAAGGATGGTACCCGCCGATTCCCTGCCACCGCA TTGGTGTGCAACTTCACCAAGCCCCAGCCCAAGAAGCCTAGTCTGCTGAAGCACGACGAGGTCGTGACCCTCTTC CACGAACTCGGCCACGGCATCCACGACCTGGTGTCCCGAACCATCTACTCCCGCTTCCACGGTACCAGCACAGTG CGCGACTTTGTCGAGGCACCCAGCCAGATGCTGGAGAACTGGTGCTGGGAACCCTCGCAGCTGCGCTCTCTGAGC CGACACTACTCCACCCTCTCCCCAGAGTACCTTGCTAGCTGGAAGGAGGCTCAGGGCGAAGCTGCCACCAGCCAG CCGTCAGAGCGCATCCCGGACGATGTCATTGCCAACCTGATTCGCACCAAGCACGTCAACGACTCCCTATTCAAC CTGCGCCAGCTGCACTTCGGCATCTTTGACATGACCGTCCACGAGCCCAAGACCCACGCCGACATTGAGGCTCTT CCTCTGTCTGCGACATACAACCGTCTCCGCCATGAGATTACCCAGATGGACGGACCGGAAGTACAGGGCGCTGGC GACGAGTGGGGCCACGGCGAGGCGACCTTTGGACATTTGATCGGAGGTTACGACGCTGGATACTACGGATACCTG AGCTCCCAAGTTTACTCCACCGACATGTTCTACACCGTCTTCAAGGACGATCCCATGAACAAGGCTGCTGGCCGT CGCTACCGCTACCAGGTTCTAGAGAAGGGTGGTAGCCAGGATGAGATGAAGACTCTGACCGAGTTCTTAGGCCGT GCGCCTCGGACCGATGCATTCTACAAGGATTTGGGACTGGCGTTAGCTGTAGATACCGATAAGCGCACCGCCTTG CCATTCTGCAATTCTCCGCAACTCAACAGCTCTTTTTCTAGATCGTCTCATTTTAGAACTTCAGCATACAAGACA ACACAGAGTCTCGGATTAAACAAGTGTATCCAATCACCGCTCTGCATCACCAACATAAGAGATCAATCTGCCTCC GCGCAGCAGCTCCAAATTCCCGACTCCTATCAGTTCAAAAGCGCGACAACAACCCGCAACATAAGCACCCTACCG CGGCGCGGCGGCGAAGGAAAAGACAAAGCGCTGATTCTGCCCCTCGAGCGCAAGAGCTCAACAGACGCAGACGCA GATGCGGATATAGAAGCCGACCTCGAAGAAGAAGCCAGGACCACAGAAACAGAACCGTCATCGCGCAAGACAAGA GCAAGGCATGTCTCTAACCACACGACGCTTCTGCTGGCTACTACGATCCCGGACCGGCGGGCGACGATTATCCGG CGCGAAGACGGGATCGAGAAGAGGATTCTGTTGAGGTGTGGGCGGTGCAAGGTTGTTGTGGGGTATTATTTGGAT CGGTTGCATTGGGCGTCTACTGGGGATCGAGAGAGGGAGAGGGGAGGGGCGCGGGATGGGGAGGAGGAGGGGGAG GAGGAGCGGCCGCCGGCTGTTTATCTTCTTCCTGGGGCTGTGGTGGAGACGGAGAAGTTGGGGGGTGAGGGGGTT GGGGAGAGGGAGTGGAGGGAGTGGGTTGTTTAG
Transcript	>Pro_DTO377G3_2|g1658.t1 ATGGCCCCCGCTCACCTCCGGAAGCCACCCCAGGCCCCGCCTGTCTTTACCGCAACCCCGCAGTCACTTCTAGCT GATGCCGAGCGCTTGATCAAGAGCTCGCGAGCCATTCAGGACAAGGTGGTGGCGGAGGTCAAGCCCGAGGCCGCA ACCTTTGCCAAGGTTGTCCTTCCTCTCGCCCAAGATGACAACCAGATGGGACTAGAGTCACACATCCTGGGCTTC TACCAGGCTGTATCAACAGACTCGAAGCTGCGAGATGCTTCTTCCAAGGCCGAAGAGCTGATGGATGAGTTCTTT ATTGAGGCGGTCATGCGTGAGGATGTCTTCAATTTGGTCGATGCCGTACTGCGCCGCAACGAGATTCTCGATCCG GAGTCACGCCGTCTATTGGAGAAGGAACACAAGGACTTCATCCGTAATGGACTCGGCCTGCCCGATGGCCCTCAT CGGCTCCGCTTCAAGGAGATCAAGAAGCGGCTGAGCCAGCTGAGCATTGAATTCCAGAAGAACCTGAACGAGGAG AACGGCGGCATTTGGTTTACCCCGGAGCAGCTGGCTGGTGTGCCCAAGGACCTTCTGGACGGCCTGAAGAAGGGC GAGGACGAGAACGCCGGCAAGCTCTGGCTGTCGTTCAAGTACCCCGACCTCTTCCCCACCATGAAATATGCCAGC GACCCCGAGACTCGCCGGCAAGTCATGATCGCCAATGAGAACAAGTGCAACCAGAATGTGCCGCTATTCCGGGAA TCCATTATACTCCGTGATGAGGCGGCTCGTCTGATCGGCTATCCCAACCACGCTGCCTTTCGTATCGAGGACAAG ATGGCCAAGACCCCAGAGACCGTTAACAAGTTTTTGGGTGATCTTCGGGACAGACTGACCGCTGGCGGGAAGAAG GAGATACAGAAGTTGCTGGATTTGAAGAACGCCACGGACCCCAATGCTGATGGCCGCTACTACCTGTGGGACCAC CGATTCTATGACCGTCTCATGCTAGAAAAGGACTACTCGCTAGACCACCAGCTTATTGCTGAGTGGTTCCCCTTG CAGACAACCATTCAAGGTATGCTGAAGATTTTCGAAGAGCTGTTCGGTCTGGAGTTTGTTGAGATCATTGGTGAG GACCGGGCAGCCATTGCCCCCACTGGCCAGGGCAATGACATTGTCTGGCACGAGGATGTCCAAGTATTCAGTGTG TGGAACGATGAGGACGCGGGCAGTGGGTTCGTTGGATACCTGTACCTGGACCTGTTCCCTCGCGAGGGCAAATAT GGCCATGCAGCCAACTTCAACCTGCAGCCGGGCTTCATTAATAAGGATGGTACCCGCCGATTCCCTGCCACCGCA TTGGTGTGCAACTTCACCAAGCCCCAGCCCAAGAAGCCTAGTCTGCTGAAGCACGACGAGGTCGTGACCCTCTTC CACGAACTCGGCCACGGCATCCACGACCTGGTGTCCCGAACCATCTACTCCCGCTTCCACGGTACCAGCACAGTG CGCGACTTTGTCGAGGCACCCAGCCAGATGCTGGAGAACTGGTGCTGGGAACCCTCGCAGCTGCGCTCTCTGAGC CGACACTACTCCACCCTCTCCCCAGAGTACCTTGCTAGCTGGAAGGAGGCTCAGGGCGAAGCTGCCACCAGCCAG CCGTCAGAGCGCATCCCGGACGATGTCATTGCCAACCTGATTCGCACCAAGCACGTCAACGACTCCCTATTCAAC CTGCGCCAGCTGCACTTCGGCATCTTTGACATGACCGTCCACGAGCCCAAGACCCACGCCGACATTGAGGCTCTT CCTCTGTCTGCGACATACAACCGTCTCCGCCATGAGATTACCCAGATGGACGGACCGGAAGTACAGGGCGCTGGC GACGAGTGGGGCCACGGCGAGGCGACCTTTGGACATTTGATCGGAGGTTACGACGCTGGATACTACGGATACCTG AGCTCCCAAGTTTACTCCACCGACATGTTCTACACCGTCTTCAAGGACGATCCCATGAACAAGGCTGCTGGCCGT CGCTACCGCTACCAGGTTCTAGAGAAGGGTGGTAGCCAGGATGAGATGAAGACTCTGACCGAGTTCTTAGGCCGT GCGCCTCGGACCGATGCATTCTACAAGGATTTGGGACTGGCGTTAGCTGTAGATACCGATAAGCGCACCGCCTTG CCATTCTGCAATTCTCCGCAACTCAACAGCTCTTTTTCTAGATCGTCTCATTTTAGAACTTCAGCATACAAGACA ACACAGAGTCTCGGATTAAACAAGTGTATCCAATCACCGCTCTGCATCACCAACATAAGAGATCAATCTGCCTCC GCGCAGCAGCTCCAAATTCCCGACTCCTATCAGTTCAAAAGCGCGACAACAACCCGCAACATAAGCACCCTACCG CGGCGCGGCGGCGAAGGAAAAGACAAAGCGCTGATTCTGCCCCTCGAGCGCAAGAGCTCAACAGACGCAGACGCA GATGCGGATATAGAAGCCGACCTCGAAGAAGAAGCCAGGACCACAGAAACAGAACCGTCATCGCGCAAGACAAGA GCAAGGCATGTCTCTAACCACACGACGCTTCTGCTGGCTACTACGATCCCGGACCGGCGGGCGACGATTATCCGG CGCGAAGACGGGATCGAGAAGAGGATTCTGTTGAGGTGTGGGCGGTGCAAGGTTGTTGTGGGGTATTATTTGGAT CGGTTGCATTGGGCGTCTACTGGGGATCGAGAGAGGGAGAGGGGAGGGGCGCGGGATGGGGAGGAGGAGGGGGAG GAGGAGCGGCCGCCGGCTGTTTATCTTCTTCCTGGGGCTGTGGTGGAGACGGAGAAGTTGGGGGGTGAGGGGGTT GGGGAGAGGGAGTGGAGGGAGTGGGTTGTTTAG
Gene	>Pro_DTO377G3_2|g1658.t1 ATGGCCCCCGCTCACCTCCGGAAGCCACCCCAGGCCCCGCCTGTCTTTACCGCAACCCCGCAGTCACTTCTAGCT GATGCCGAGCGCTTGATCAAGAGCTCGCGAGCCATTCAGGACAAGGTGGTGGCGGAGGTCAAGCCCGAGGCCGCA ACCTTTGCCAAGGTTGTCCTTCCTCTCGCCCAAGATGACAACCAGATGGGACTAGAGTCACACATCCTGGGCTTC TACCAGGCTGTATCAACAGACTCGAAGCTGCGAGATGCTTCTTCCAAGGCCGAAGAGCTGATGGATGAGTTCTTT ATTGAGGCGGTCATGCGTGAGGATGTCTTCAATTTGGTCGATGCCGTACTGCGCCGCAACGAGATTCTCGATCCG GAGTCACGCCGTCTATTGGAGAAGGAACACAAGGACTTCATCCGTAATGGACTCGGCCTGCCCGATGGCCCTCAT CGGCTCCGCTTCAAGGAGATCAAGAAGCGGCTGAGCCAGCTGAGCATTGAATTCCAGAAGAACCTGAACGAGGAG AACGGCGGCATTTGGTTTACCCCGGAGCAGCTGGCTGGTGTGCCCAAGGACCTTCTGGACGGCCTGAAGAAGGGC GAGGACGAGAACGCCGGCAAGCTCTGGCTGTCGTTCAAGTACCCCGACCTCTTCCCCACCATGAAATATGCCAGC GACCCCGAGACTCGCCGGCAAGTCATGATCGCCAATGAGAACAAGTGCAACCAGAATGTGCCGCTATTCCGGGAA TCCATTATACTCCGTGATGAGGCGGCTCGTCTGATCGGCTATCCCAACCACGCTGCCTTTCGTATCGAGGACAAG ATGGCCAAGACCCCAGAGACCGTTAACAAGTTTTTGGGTGATCTTCGGGACAGACTGACCGCTGGCGGGAAGAAG GAGATACAGAAGTTGCTGGATTTGAAGAACGCCACGGACCCCAATGCTGATGGCCGCTACTACCTGTGGGACCAC CGATTCTATGACCGTCTCATGCTAGAAAAGGACTACTCGCTAGACCACCAGCTTATTGCTGAGTGGTTCCCCTTG CAGACAACCATTCAAGGTATGCTGAAGATTTTCGAAGAGCTGTTCGGTCTGGAGTTTGTTGAGATCATTGGTGAG GACCGGGCAGCCATTGCCCCCACTGGCCAGGGCAATGACATTGTCTGGCACGAGGATGTCCAAGTATTCAGTGTG TGGAACGATGAGGACGCGGGCAGTGGGTTCGTTGGATACCTGTACCTGGACCTGTTCCCTCGCGAGGGCAAATAT GGCCATGCAGCCAACTTCAACCTGCAGCCGGGCTTCATTAATAAGGATGGTACCCGCCGATTCCCTGCCACCGCA TTGGTGTGCAACTTCACCAAGCCCCAGCCCAAGAAGCCTAGTCTGCTGAAGCACGACGAGGTCGTGACCCTCTTC CACGAACTCGGCCACGGCATCCACGACCTGGTGTCCCGAACCATCTACTCCCGCTTCCACGGTACCAGCACAGTG CGCGACTTTGTCGAGGCACCCAGCCAGATGCTGGAGAACTGGTGCTGGGAACCCTCGCAGCTGCGCTCTCTGAGC CGACACTACTCCACCCTCTCCCCAGAGTACCTTGCTAGCTGGAAGGAGGCTCAGGGCGAAGCTGCCACCAGCCAG CCGTCAGAGCGCATCCCGGACGATGTCATTGCCAACCTGATTCGCACCAAGCACGTCAACGACTCCCTATTCAAC CTGCGCCAGCTGCACTTCGGCATCTTTGACATGACCGTCCACGAGCCCAAGACCCACGCCGACATTGAGGCTCTT CCTCTGTCTGCGACATACAACCGTCTCCGCCATGAGATTACCCAGATGGACGGACCGGAAGTACAGGGCGCTGGC GACGAGTGGGGCCACGGCGAGGCGACCTTTGGACATTTGATCGGAGGTTACGACGCTGGATACTACGGATACCTG AGGTAAGTTATAAGTTTGTGTGATTGGTTTCAATGTTCGAATACTGATGATTTCGCTCTGCAGCTCCCAAGTTTA CTCCACCGACATGTTCTACACCGTCTTCAAGGACGATCCCATGAACAAGGCTGCTGGCCGTCGCTACCGCTACCA GGTTCTAGAGAAGGGTGGTAGCCAGGATGAGATGAAGACTCTGACCGAGTTCTTAGGCCGTGCGCCTCGGACCGA TGCATTCTACAAGGATTTGGGACTGGCGTAAAGTGGTGCGTAGCATTTACAGCCATCGGGGCTTATGAACGGCTA TAAACTATACCTATTAAATTATATAGAGCTATCCGAATGCGTATCTTGTGCTCATGAATAACGAGCAGCATGCCA ATAACTCCTCTACTTGAACTGTCTATATCGTAGCTAACAAGTTCCAAGGTTAGCTGTAGATACCGATAAGCGCAC CGCCTTGCCATTCTGCAATTCTCCGCAACTCAACAGCTCTTTTTCTAGATCGTCTCATTTTAGAACTTCAGCATA CAAGACAACACAGAGTCTCGGATTAAACAAGTGTATCCAATCACCGGTAAGTACCTACTAAGCCAGCAGAAAGAT ATTTCCTCATGAACCCCGCGCAAAAGACTAACCAAGACCCCAGCTCTGCATCACCAACATAAGAGATCAATCTGC CTCCGCGCAGCAGCTCCAAATTCCCGACTCCTATCAGTTCAAAAGCGCGAGTCAATAACCAATTCCAAAAATGAC CGACCACCGTCTCCCAATCCAAACCCAACATTGCCGCTTCTGCAACCACCTCCTGCTAGCAACAACCCGCAACAT AAGCACCCTACCGCGGCGCGGCGGCGAAGGAAAAGACAAAGCGCTGATTCTGCCCCTCGAGCGCAAGAGCTCAAC AGACGCAGACGCAGATGCGGATATAGAAGCCGACCTCGAAGAAGAAGCCAGGACCACAGAAACAGAACCGTCATC GCGCAAGACAAGAGCAAGGCATGTCTCTAACCACACGACGCTTCTGCTGGCTACTACGATCCCGGACCGGCGGGC GACGATTATCCGGCGCGAAGACGGGATCGAGAAGAGGATTCTGTTGAGGTGTGGGCGGTGCAAGGTTGTTGTGGG GTATTATTTGGATCGGTTGCATTGGGCGTCTACTGGGGATCGAGAGAGGGAGAGGGGAGGGGCGCGGGATGGGGA GGAGGAGGGGGAGGAGGAGCGGCCGCCGGCTGTTTATCTTCTTCCTGGGGCTGTGGTGGAGACGGAGAAGTTGGG GGGTGAGGGGGTTGGGGAGAGGGAGTGGAGGGAGTGGGTTGTTTAG