Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g1474.t1
Gene name
Location	scaffold_02:61153..64546
Strand	+
Gene length (bp)	3393
Transcript length (bp)	3342
Coding sequence length (bp)	3342
Protein length (aa)	1114

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00617	RasGEF	RasGEF domain	2.9E-51	828	1011
PF00618	RasGEF_N	RasGEF N-terminal motif	2.0E-14	649	741
PF00018	SH3_1	SH3 domain	3.4E-05	47	82

GO

GO Term	Description	Terminal node
GO:0005515	protein binding	Yes
GO:0007264	small GTPase mediated signal transduction	Yes
GO:0005085	guanyl-nucleotide exchange factor activity	Yes
GO:0008150	biological_process	No
GO:0009987	cellular process	No
GO:0005488	binding	No
GO:0065007	biological regulation	No
GO:0007165	signal transduction	No
GO:0051020	GTPase binding	No
GO:0098772	molecular function regulator	No
GO:0019899	enzyme binding	No
GO:0050794	regulation of cellular process	No
GO:0050789	regulation of biological process	No
GO:0003674	molecular_function	No
GO:0035556	intracellular signal transduction	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 31	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1474.t1 MTPPLTPQNAQDTNMDQLEAPRPVFHNYLRAFYPFHPAGNVSPSTVTLPLDQGDIILVHSVHTNGWADGTLLDSG NRGWLPTNYCEAYDQLPMRPLLKALTDFWDIIRGNFGSSLKDFGNQDLMRGPIAGVRFLLEKSECLTRESALVRR FEGLRRIRKALLSDLSSLVKTAKKFQEIANGLPSEDEVEAILDEMLLKAFKIVTRGVRFLDVWNEEVGLGRTIAE MDGPNESSGQYSMPPTPASETFNLGENEGPDRSASRMLESRMDHSRMDMSRSSMRTEMVDPRPASVATKRVSVSH RMSVSGPSTAIVAQNLASERLGTTYDAFLGVLGSFLGFHMQSRSSMELVVTTQQAVEACKQLLNVIEVVCEHGTH RSAFLEQARELMWEKLSELVHAARDVFRPAQMPEDDLFFMVDEGKRLVGAATDCVRAAGNCLAKARLVLEQIGDL ELDPEHFEEERQELSSVASPQDEPQTPVEEERQEMSRLPPPPLQIPSTPALTDATTPSSFQSLPANSPANITAIS SLPNSAILPTHLENISSFSSTDSNYRESHPKSDMSESFGRGITSNGSSFTYNSHARDSEMSGVSQTSTRATSPDI GGSFQGSFKVHSLKESLSYSTLAEENEETEANILEKTFAHELIYKEGSVMGGSLRALIEKLTAHQSTPDAMFVST FYLTFRLFATPLEFAEALAERFDYIGETPHAAGPVRLRVYNIFKGWLESHWRHDRDNTALEFIVDFASTRLMADL PTAGMRLLDLAGKVSSVGGPLVPRLISSMGKTNTSIAQYIHPDTPLPPPILGKKEHHLLKQWKNGEASITILDFD PLELARQLTIKESRIFCSILPEELLNTEWTPKSGSLAVNVRAMSTLSTDLAHLVADSILYLEEPKKRAATIKHWV KIANKCLELNNYDSLMAIICSLNSSMISRLKKTWDIVSQKTKTVLEQLCGIVDVSRNYAVLRQRLQNHVPPCLPF VGTYLTDLTFVDHGNQSLRTLSTHDSEMTVINFDKHMKTARIISELQRFQIPYRLTEVPELQVWMQNEFVRVRSN GEITTQTFYRRSLVLEPREASRSANNLQSQSEPMPSMLDNAKDKFDFLSWTNHPKAKSVPTHG*
Coding	>Pro_DTO377G3_2|g1474.t1 ATGACCCCTCCGTTAACGCCACAAAACGCCCAGGACACAAACATGGATCAATTGGAAGCCCCGAGGCCTGTCTTT CACAACTATCTGCGCGCCTTCTACCCTTTTCACCCGGCTGGCAATGTCTCTCCTTCGACCGTTACACTCCCGCTG GACCAGGGAGATATCATTTTGGTACACTCCGTTCACACCAATGGCTGGGCCGATGGTACATTATTAGATTCTGGG AATCGCGGCTGGTTACCCACGAATTACTGCGAGGCTTACGACCAATTACCCATGCGTCCTTTGTTGAAGGCCTTG ACTGATTTCTGGGATATCATTCGAGGAAACTTCGGGTCATCACTGAAGGACTTTGGAAATCAAGACTTGATGAGA GGCCCTATCGCTGGCGTCCGCTTTCTACTAGAAAAATCAGAATGTCTTACTCGAGAATCCGCTCTGGTAAGGCGA TTTGAGGGACTACGCAGAATTCGAAAGGCTTTGCTATCTGACCTGTCTTCGCTGGTGAAAACTGCGAAAAAGTTC CAGGAAATTGCAAACGGGCTCCCGTCAGAAGACGAGGTTGAGGCCATTCTGGATGAGATGCTTCTCAAGGCTTTC AAGATTGTTACTAGAGGAGTTCGATTCCTCGACGTCTGGAACGAGGAGGTAGGCTTGGGTCGGACTATCGCCGAG ATGGATGGGCCCAACGAAAGCTCAGGCCAGTATAGCATGCCACCGACTCCTGCATCCGAAACTTTCAACTTGGGC GAGAACGAGGGACCTGATCGATCTGCGTCGCGAATGCTGGAATCACGAATGGACCATAGCCGGATGGATATGAGT CGATCATCGATGCGCACGGAGATGGTTGATCCTAGACCGGCCTCCGTCGCTACCAAACGGGTTTCTGTATCCCAC CGCATGTCAGTCTCCGGCCCTTCGACTGCCATCGTTGCCCAGAATCTGGCATCCGAACGCCTGGGAACAACATAT GATGCATTCCTCGGCGTACTTGGCTCATTCCTCGGGTTCCATATGCAGTCCCGCTCCTCGATGGAGTTGGTTGTC ACTACACAGCAGGCTGTCGAGGCATGCAAGCAATTGCTAAACGTCATTGAGGTAGTATGTGAGCATGGTACACAT CGCAGCGCGTTTCTCGAACAGGCACGAGAGTTAATGTGGGAGAAGCTATCTGAGCTCGTTCACGCTGCACGCGAC GTGTTTCGTCCCGCACAAATGCCAGAAGATGATCTATTTTTCATGGTAGATGAAGGAAAACGCCTTGTGGGTGCT GCGACTGACTGTGTCCGAGCAGCTGGAAACTGTTTGGCCAAGGCTCGCCTGGTGCTTGAGCAAATTGGTGACCTT GAGCTTGACCCTGAACACTTCGAAGAGGAAAGACAGGAATTGTCTAGCGTTGCCTCTCCACAAGATGAACCGCAG ACTCCCGTAGAAGAAGAGCGACAGGAGATGTCACGTCTTCCCCCACCTCCTCTTCAGATCCCTAGCACACCTGCT CTCACCGACGCTACAACACCTTCATCCTTTCAGTCTCTTCCTGCAAATTCCCCCGCCAACATCACCGCCATTTCT TCTTTACCTAATTCTGCCATACTCCCCACCCACCTCGAGAACATCTCTTCCTTCTCCTCCACTGACAGTAACTAC CGTGAAAGTCATCCCAAGTCTGATATGAGCGAATCATTCGGACGTGGAATTACAAGCAATGGCAGCAGCTTCACG TATAATAGCCATGCACGTGATTCTGAGATGAGTGGCGTTTCCCAAACCTCGACTCGGGCTACCTCGCCTGATATT GGGGGTAGCTTCCAGGGTAGCTTCAAGGTTCACTCGCTGAAGGAGAGTCTGAGCTACTCCACCCTCGCCGAGGAA AATGAGGAGACTGAGGCCAACATCCTGGAGAAGACTTTCGCACACGAACTTATTTACAAGGAAGGTTCGGTGATG GGCGGGAGTTTGCGTGCTCTTATTGAGAAGCTGACTGCTCATCAATCTACCCCCGATGCCATGTTTGTTTCAACC TTCTACCTCACCTTCCGTCTGTTTGCTACGCCTCTTGAGTTTGCCGAGGCCCTCGCTGAACGCTTCGACTATATT GGTGAGACACCCCACGCCGCCGGACCCGTCCGTCTGCGTGTATACAACATCTTCAAGGGCTGGCTCGAGTCGCAC TGGCGCCACGACCGCGACAACACGGCCCTGGAGTTCATCGTCGACTTCGCAAGCACACGACTTATGGCGGACCTT CCCACTGCTGGTATGAGGTTGCTTGATTTGGCCGGCAAGGTGTCCTCCGTTGGTGGTCCTCTTGTGCCTCGCCTG ATATCTTCCATGGGCAAGACCAACACTTCCATTGCCCAATACATTCACCCCGATACTCCCTTACCCCCTCCCATC CTTGGCAAGAAGGAGCACCACTTGCTCAAGCAATGGAAGAACGGCGAAGCCTCTATAACCATCCTTGACTTCGAC CCACTTGAGCTCGCCCGCCAGCTCACCATTAAGGAGTCACGCATTTTCTGCTCGATCCTTCCCGAAGAACTGCTG AACACGGAATGGACTCCAAAGTCAGGATCGTTGGCTGTGAACGTTCGCGCCATGTCAACTCTCTCGACTGACCTC GCCCACCTCGTTGCTGACTCTATCCTATACCTCGAGGAGCCTAAGAAGCGTGCCGCTACCATCAAGCACTGGGTC AAGATTGCGAACAAATGTCTAGAGTTGAACAACTACGACTCCCTCATGGCGATAATCTGCTCATTGAACTCGTCT ATGATCTCTCGACTGAAGAAGACCTGGGACATCGTATCGCAGAAGACCAAGACTGTCCTCGAGCAGCTCTGCGGT ATCGTGGATGTGTCTCGCAACTACGCAGTACTCCGTCAGCGCCTTCAGAACCACGTCCCTCCTTGCCTTCCATTT GTCGGTACCTACCTGACCGACCTCACCTTCGTCGACCACGGCAACCAATCTCTCCGCACCCTCTCCACCCATGAC AGTGAAATGACTGTCATCAACTTCGACAAGCACATGAAGACAGCCCGTATTATCAGCGAGCTCCAACGGTTCCAG ATCCCCTACCGTCTGACCGAAGTCCCAGAGCTACAGGTCTGGATGCAGAATGAGTTTGTGCGCGTGCGCTCAAAC GGCGAAATCACCACACAAACCTTCTACCGCCGCTCTCTGGTTCTCGAGCCTAGAGAAGCCTCCCGCAGCGCAAAC AACCTTCAGTCCCAGTCCGAGCCCATGCCTTCCATGCTTGACAATGCCAAGGACAAGTTCGACTTCCTCTCATGG ACCAACCATCCCAAGGCGAAGTCCGTCCCGACACACGGATAA
Transcript	>Pro_DTO377G3_2|g1474.t1 ATGACCCCTCCGTTAACGCCACAAAACGCCCAGGACACAAACATGGATCAATTGGAAGCCCCGAGGCCTGTCTTT CACAACTATCTGCGCGCCTTCTACCCTTTTCACCCGGCTGGCAATGTCTCTCCTTCGACCGTTACACTCCCGCTG GACCAGGGAGATATCATTTTGGTACACTCCGTTCACACCAATGGCTGGGCCGATGGTACATTATTAGATTCTGGG AATCGCGGCTGGTTACCCACGAATTACTGCGAGGCTTACGACCAATTACCCATGCGTCCTTTGTTGAAGGCCTTG ACTGATTTCTGGGATATCATTCGAGGAAACTTCGGGTCATCACTGAAGGACTTTGGAAATCAAGACTTGATGAGA GGCCCTATCGCTGGCGTCCGCTTTCTACTAGAAAAATCAGAATGTCTTACTCGAGAATCCGCTCTGGTAAGGCGA TTTGAGGGACTACGCAGAATTCGAAAGGCTTTGCTATCTGACCTGTCTTCGCTGGTGAAAACTGCGAAAAAGTTC CAGGAAATTGCAAACGGGCTCCCGTCAGAAGACGAGGTTGAGGCCATTCTGGATGAGATGCTTCTCAAGGCTTTC AAGATTGTTACTAGAGGAGTTCGATTCCTCGACGTCTGGAACGAGGAGGTAGGCTTGGGTCGGACTATCGCCGAG ATGGATGGGCCCAACGAAAGCTCAGGCCAGTATAGCATGCCACCGACTCCTGCATCCGAAACTTTCAACTTGGGC GAGAACGAGGGACCTGATCGATCTGCGTCGCGAATGCTGGAATCACGAATGGACCATAGCCGGATGGATATGAGT CGATCATCGATGCGCACGGAGATGGTTGATCCTAGACCGGCCTCCGTCGCTACCAAACGGGTTTCTGTATCCCAC CGCATGTCAGTCTCCGGCCCTTCGACTGCCATCGTTGCCCAGAATCTGGCATCCGAACGCCTGGGAACAACATAT GATGCATTCCTCGGCGTACTTGGCTCATTCCTCGGGTTCCATATGCAGTCCCGCTCCTCGATGGAGTTGGTTGTC ACTACACAGCAGGCTGTCGAGGCATGCAAGCAATTGCTAAACGTCATTGAGGTAGTATGTGAGCATGGTACACAT CGCAGCGCGTTTCTCGAACAGGCACGAGAGTTAATGTGGGAGAAGCTATCTGAGCTCGTTCACGCTGCACGCGAC GTGTTTCGTCCCGCACAAATGCCAGAAGATGATCTATTTTTCATGGTAGATGAAGGAAAACGCCTTGTGGGTGCT GCGACTGACTGTGTCCGAGCAGCTGGAAACTGTTTGGCCAAGGCTCGCCTGGTGCTTGAGCAAATTGGTGACCTT GAGCTTGACCCTGAACACTTCGAAGAGGAAAGACAGGAATTGTCTAGCGTTGCCTCTCCACAAGATGAACCGCAG ACTCCCGTAGAAGAAGAGCGACAGGAGATGTCACGTCTTCCCCCACCTCCTCTTCAGATCCCTAGCACACCTGCT CTCACCGACGCTACAACACCTTCATCCTTTCAGTCTCTTCCTGCAAATTCCCCCGCCAACATCACCGCCATTTCT TCTTTACCTAATTCTGCCATACTCCCCACCCACCTCGAGAACATCTCTTCCTTCTCCTCCACTGACAGTAACTAC CGTGAAAGTCATCCCAAGTCTGATATGAGCGAATCATTCGGACGTGGAATTACAAGCAATGGCAGCAGCTTCACG TATAATAGCCATGCACGTGATTCTGAGATGAGTGGCGTTTCCCAAACCTCGACTCGGGCTACCTCGCCTGATATT GGGGGTAGCTTCCAGGGTAGCTTCAAGGTTCACTCGCTGAAGGAGAGTCTGAGCTACTCCACCCTCGCCGAGGAA AATGAGGAGACTGAGGCCAACATCCTGGAGAAGACTTTCGCACACGAACTTATTTACAAGGAAGGTTCGGTGATG GGCGGGAGTTTGCGTGCTCTTATTGAGAAGCTGACTGCTCATCAATCTACCCCCGATGCCATGTTTGTTTCAACC TTCTACCTCACCTTCCGTCTGTTTGCTACGCCTCTTGAGTTTGCCGAGGCCCTCGCTGAACGCTTCGACTATATT GGTGAGACACCCCACGCCGCCGGACCCGTCCGTCTGCGTGTATACAACATCTTCAAGGGCTGGCTCGAGTCGCAC TGGCGCCACGACCGCGACAACACGGCCCTGGAGTTCATCGTCGACTTCGCAAGCACACGACTTATGGCGGACCTT CCCACTGCTGGTATGAGGTTGCTTGATTTGGCCGGCAAGGTGTCCTCCGTTGGTGGTCCTCTTGTGCCTCGCCTG ATATCTTCCATGGGCAAGACCAACACTTCCATTGCCCAATACATTCACCCCGATACTCCCTTACCCCCTCCCATC CTTGGCAAGAAGGAGCACCACTTGCTCAAGCAATGGAAGAACGGCGAAGCCTCTATAACCATCCTTGACTTCGAC CCACTTGAGCTCGCCCGCCAGCTCACCATTAAGGAGTCACGCATTTTCTGCTCGATCCTTCCCGAAGAACTGCTG AACACGGAATGGACTCCAAAGTCAGGATCGTTGGCTGTGAACGTTCGCGCCATGTCAACTCTCTCGACTGACCTC GCCCACCTCGTTGCTGACTCTATCCTATACCTCGAGGAGCCTAAGAAGCGTGCCGCTACCATCAAGCACTGGGTC AAGATTGCGAACAAATGTCTAGAGTTGAACAACTACGACTCCCTCATGGCGATAATCTGCTCATTGAACTCGTCT ATGATCTCTCGACTGAAGAAGACCTGGGACATCGTATCGCAGAAGACCAAGACTGTCCTCGAGCAGCTCTGCGGT ATCGTGGATGTGTCTCGCAACTACGCAGTACTCCGTCAGCGCCTTCAGAACCACGTCCCTCCTTGCCTTCCATTT GTCGGTACCTACCTGACCGACCTCACCTTCGTCGACCACGGCAACCAATCTCTCCGCACCCTCTCCACCCATGAC AGTGAAATGACTGTCATCAACTTCGACAAGCACATGAAGACAGCCCGTATTATCAGCGAGCTCCAACGGTTCCAG ATCCCCTACCGTCTGACCGAAGTCCCAGAGCTACAGGTCTGGATGCAGAATGAGTTTGTGCGCGTGCGCTCAAAC GGCGAAATCACCACACAAACCTTCTACCGCCGCTCTCTGGTTCTCGAGCCTAGAGAAGCCTCCCGCAGCGCAAAC AACCTTCAGTCCCAGTCCGAGCCCATGCCTTCCATGCTTGACAATGCCAAGGACAAGTTCGACTTCCTCTCATGG ACCAACCATCCCAAGGCGAAGTCCGTCCCGACACACGGATAA
Gene	>Pro_DTO377G3_2|g1474.t1 ATGACCCCTCCGTTAACGCCACAAAACGCCCAGGACACAAACATGGATCAATTGGAAGCCCCGAGGCCTGTCTTT CACAACTATCTGCGCGCCTTCTACCCTTTTCACCCGGCTGGCAATGTCTCTCCTTCGACCGTTACACTCCCGCTG GACCAGGGAGATATCATTTTGGTACACTCCGTTCACACCAATGGCTGGGCCGATGGTACATTATTAGATTCTGGG AATCGCGGCTGGTTACCCACGAATTACTGCGAGGCTTACGACCAATTACCCATGCGTCCTTTGTTGAAGGCCTTG ACTGATTTCTGGGATATCATTCGAGGAAACTTCGGGTCATCACTGAAGGACTTTGGAAATCAAGACTTGATGAGA GGCCCTATCGCTGGCGTCCGCTTTCTACTAGTAAGTATGAATTAGAACCGAGAAACAATTACGGGGCTTATCATT CCACAGGAAAAATCAGAATGTCTTACTCGAGAATCCGCTCTGGTAAGGCGATTTGAGGGACTACGCAGAATTCGA AAGGCTTTGCTATCTGACCTGTCTTCGCTGGTGAAAACTGCGAAAAAGTTCCAGGAAATTGCAAACGGGCTCCCG TCAGAAGACGAGGTTGAGGCCATTCTGGATGAGATGCTTCTCAAGGCTTTCAAGATTGTTACTAGAGGAGTTCGA TTCCTCGACGTCTGGAACGAGGAGGTAGGCTTGGGTCGGACTATCGCCGAGATGGATGGGCCCAACGAAAGCTCA GGCCAGTATAGCATGCCACCGACTCCTGCATCCGAAACTTTCAACTTGGGCGAGAACGAGGGACCTGATCGATCT GCGTCGCGAATGCTGGAATCACGAATGGACCATAGCCGGATGGATATGAGTCGATCATCGATGCGCACGGAGATG GTTGATCCTAGACCGGCCTCCGTCGCTACCAAACGGGTTTCTGTATCCCACCGCATGTCAGTCTCCGGCCCTTCG ACTGCCATCGTTGCCCAGAATCTGGCATCCGAACGCCTGGGAACAACATATGATGCATTCCTCGGCGTACTTGGC TCATTCCTCGGGTTCCATATGCAGTCCCGCTCCTCGATGGAGTTGGTTGTCACTACACAGCAGGCTGTCGAGGCA TGCAAGCAATTGCTAAACGTCATTGAGGTAGTATGTGAGCATGGTACACATCGCAGCGCGTTTCTCGAACAGGCA CGAGAGTTAATGTGGGAGAAGCTATCTGAGCTCGTTCACGCTGCACGCGACGTGTTTCGTCCCGCACAAATGCCA GAAGATGATCTATTTTTCATGGTAGATGAAGGAAAACGCCTTGTGGGTGCTGCGACTGACTGTGTCCGAGCAGCT GGAAACTGTTTGGCCAAGGCTCGCCTGGTGCTTGAGCAAATTGGTGACCTTGAGCTTGACCCTGAACACTTCGAA GAGGAAAGACAGGAATTGTCTAGCGTTGCCTCTCCACAAGATGAACCGCAGACTCCCGTAGAAGAAGAGCGACAG GAGATGTCACGTCTTCCCCCACCTCCTCTTCAGATCCCTAGCACACCTGCTCTCACCGACGCTACAACACCTTCA TCCTTTCAGTCTCTTCCTGCAAATTCCCCCGCCAACATCACCGCCATTTCTTCTTTACCTAATTCTGCCATACTC CCCACCCACCTCGAGAACATCTCTTCCTTCTCCTCCACTGACAGTAACTACCGTGAAAGTCATCCCAAGTCTGAT ATGAGCGAATCATTCGGACGTGGAATTACAAGCAATGGCAGCAGCTTCACGTATAATAGCCATGCACGTGATTCT GAGATGAGTGGCGTTTCCCAAACCTCGACTCGGGCTACCTCGCCTGATATTGGGGGTAGCTTCCAGGGTAGCTTC AAGGTTCACTCGCTGAAGGAGAGTCTGAGCTACTCCACCCTCGCCGAGGAAAATGAGGAGACTGAGGCCAACATC CTGGAGAAGACTTTCGCACACGAACTTATTTACAAGGAAGGTTCGGTGATGGGCGGGAGTTTGCGTGCTCTTATT GAGAAGCTGACTGCTCATCAATCTACCCCCGATGCCATGTTTGTTTCAACCTTCTACCTCACCTTCCGTCTGTTT GCTACGCCTCTTGAGTTTGCCGAGGCCCTCGCTGAACGCTTCGACTATATTGGTGAGACACCCCACGCCGCCGGA CCCGTCCGTCTGCGTGTATACAACATCTTCAAGGGCTGGCTCGAGTCGCACTGGCGCCACGACCGCGACAACACG GCCCTGGAGTTCATCGTCGACTTCGCAAGCACACGACTTATGGCGGACCTTCCCACTGCTGGTATGAGGTTGCTT GATTTGGCCGGCAAGGTGTCCTCCGTTGGTGGTCCTCTTGTGCCTCGCCTGATATCTTCCATGGGCAAGACCAAC ACTTCCATTGCCCAATACATTCACCCCGATACTCCCTTACCCCCTCCCATCCTTGGCAAGAAGGAGCACCACTTG CTCAAGCAATGGAAGAACGGCGAAGCCTCTATAACCATCCTTGACTTCGACCCACTTGAGCTCGCCCGCCAGCTC ACCATTAAGGAGTCACGCATTTTCTGCTCGATCCTTCCCGAAGAACTGCTGAACACGGAATGGACTCCAAAGTCA GGATCGTTGGCTGTGAACGTTCGCGCCATGTCAACTCTCTCGACTGACCTCGCCCACCTCGTTGCTGACTCTATC CTATACCTCGAGGAGCCTAAGAAGCGTGCCGCTACCATCAAGCACTGGGTCAAGATTGCGAACAAATGTCTAGAG TTGAACAACTACGACTCCCTCATGGCGATAATCTGCTCATTGAACTCGTCTATGATCTCTCGACTGAAGAAGACC TGGGACATCGTATCGCAGAAGACCAAGACTGTCCTCGAGCAGCTCTGCGGTATCGTGGATGTGTCTCGCAACTAC GCAGTACTCCGTCAGCGCCTTCAGAACCACGTCCCTCCTTGCCTTCCATTTGTCGGTACCTACCTGACCGACCTC ACCTTCGTCGACCACGGCAACCAATCTCTCCGCACCCTCTCCACCCATGACAGTGAAATGACTGTCATCAACTTC GACAAGCACATGAAGACAGCCCGTATTATCAGCGAGCTCCAACGGTTCCAGATCCCCTACCGTCTGACCGAAGTC CCAGAGCTACAGGTCTGGATGCAGAATGAGTTTGTGCGCGTGCGCTCAAACGGCGAAATCACCACACAAACCTTC TACCGCCGCTCTCTGGTTCTCGAGCCTAGAGAAGCCTCCCGCAGCGCAAACAACCTTCAGTCCCAGTCCGAGCCC ATGCCTTCCATGCTTGACAATGCCAAGGACAAGTTCGACTTCCTCTCATGGACCAACCATCCCAAGGCGAAGTCC GTCCCGACACACGGATAA