Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Pro_DTO377G3_2|g1241.t1
Gene name
Location	scaffold_01:3268598..3272551
Strand	+
Gene length (bp)	3953
Transcript length (bp)	3642
Coding sequence length (bp)	3642
Protein length (aa)	1214

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF04053	Coatomer_WDAD	Coatomer WD associated region	3.7E-147	350	778
PF06957	COPI_C	Coatomer (COPI) alpha subunit C-terminus	7.5E-101	851	1208
PF00400	WD40	WD domain, G-beta repeat	5.6E-06	51	85
PF00400	WD40	WD domain, G-beta repeat	4.0E-08	90	127
PF00400	WD40	WD domain, G-beta repeat	2.9E-06	133	169
PF00400	WD40	WD domain, G-beta repeat	4.2E-04	210	242
PF00400	WD40	WD domain, G-beta repeat	3.2E-02	252	287

GO

GO Term	Description	Terminal node
GO:0030117	membrane coat	Yes
GO:0016192	vesicle-mediated transport	Yes
GO:0005198	structural molecule activity	Yes
GO:0030126	COPI vesicle coat	Yes
GO:0005515	protein binding	Yes
GO:0006886	intracellular protein transport	Yes
GO:0030120	vesicle coat	No
GO:0045184	establishment of protein localization	No
GO:0046907	intracellular transport	No
GO:0006810	transport	No
GO:0008150	biological_process	No
GO:0015031	protein transport	No
GO:0005575	cellular_component	No
GO:0051234	establishment of localization	No
GO:0051641	cellular localization	No
GO:0005488	binding	No
GO:0032991	protein-containing complex	No
GO:0071702	organic substance transport	No
GO:0003674	molecular_function	No
GO:0070727	cellular macromolecule localization	No
GO:0051649	establishment of localization in cell	No
GO:0051179	localization	No
GO:0008104	protein localization	No
GO:0071705	nitrogen compound transport	No
GO:0033036	macromolecule localization	No
GO:0098796	membrane protein complex	No
GO:0009987	cellular process	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 39	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1241.t1 MQSSPNMLTKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRGVDFHPTQPLFVSG GDDYKIKVWNYQTRRCLFTLNGHLDYVRTVFFHPELPWILSASDDQTIRIWNWQNRSLICTMTGHNHYVMCAQFH PTEDLIASASLDQSVRIWDISGLRKKHSAPTSVSFEDQMARANPNQADMFGNTDAIVKFVLEGHDRGVNWVSFHP TLPLLVSAGDDRLVKLWRMSDTKAWEVDTCRGHFQNASAALFHPHQDLILSVGEDKTIRAWDLNKRTSVQSFKRD LDRFWVIAAHPEMNLFAAGHDTGVMVFKLERERPASAIYQNQLFYITKDKHVKSYDFSKNVESPPLLSLRKLGSP WVPPRTLSYNPAERAILVTTPADNGTYELIHLPRDGTGAVEPTDVKRGQATSAVFVARNRFAVFSPSTQQVDIKD LSNSTTKTIKPPAGTTDIYFGGTGCLLFITPTHVTLFDIQQKKQLAELAVSGVKYVVWSNDGLYCALLSKHNVTI VTKTLEQVSTLHETIRIKSATWDDAGVLLYSTLNHVKYSLLNGDNGIIRTLDQTVYLVRVKGRNVYALDRNAQPR ILEIDPTEYRFKLALVKRNYDEMLQIIKTSSLVGQSIISYLQKKGYPEIALQFVQDPQTRFDLALECGNLEVANE MARELDRPNFWTRLGAEALAHGNHQIVEMTYQKQRSFDKLSFLYLSTGDQEKLSRMAKIAEHRGDFTSRFQNAIY RGDVEDRIQMFKEVDLYPLAYLTAKSNGLVEEAESILEAVGLTEDQIVLPTLDQPLKVPHPIVPTFNSNWPVKAA GHSSFEKALLGEVGVADEEAGAVGFEIEEEEQEADVARETLDDDEEAVSGWDMGDDVIVEEEIDFVNVESAEAGA GSSEADLWARNSPLAADHVAAGSFDTAMQLLNRQVGAVQFAPLKPRFLEVYKATKTYLPATAGLPPLINYVRRTI DETDSRKMLPIIPRDLETVASVDLQEGYAAMRSNRLEEGVATFKRILHTVLVNTVSSEADVDEAKKIIATAREYI LAMSIELERRTLSTNSPEDLKRSLELSAYFTIPKLEVAHRQLALMAAMKLAFANKNYGSALSFANRMLANGGSAK LLEQAKKIKAQCERNPQDQIDIDFDPFAEFDICAASFTPIYSGSPSVSDPFTGAKYHPQYKGSVDRISEVTEIGA PASGLRLFVPSQF*
Coding	>Pro_DTO377G3_2|g1241.t1 ATGCAGTCCTCCCCAAACATGCTCACCAAGTTTGAGTCCAAATCCTCCAGAGCTAAAGGAATCGCGTTCCATCCC AAACGACCATGGATCCTCGTCTCCCTTCACTCATCCACAATCCAACTGTGGGACTACCGTATGGGAACTCTTATC GACCGATTCGAAGAACACGATGGCCCGGTTCGCGGCGTTGACTTCCACCCAACCCAGCCCCTGTTTGTATCGGGA GGTGACGACTACAAGATCAAGGTCTGGAACTACCAGACTCGGAGGTGCTTGTTCACATTGAATGGCCACTTGGAT TATGTGCGAACAGTTTTCTTCCACCCCGAGCTGCCCTGGATTCTGTCTGCGTCCGACGACCAGACCATCCGAATC TGGAACTGGCAAAATCGGTCACTCATCTGTACGATGACCGGTCACAACCATTATGTTATGTGCGCTCAGTTCCAC CCCACCGAGGATCTCATTGCCTCGGCCTCGTTGGATCAGTCAGTTCGCATTTGGGATATCTCCGGCCTGCGGAAG AAGCACTCGGCCCCAACCTCGGTTTCCTTCGAAGACCAAATGGCAAGAGCCAACCCAAACCAAGCCGATATGTTC GGAAACACCGATGCAATCGTTAAATTTGTGCTGGAAGGTCATGACCGTGGTGTTAACTGGGTCTCGTTCCACCCC ACACTACCCTTGCTCGTGTCAGCCGGTGACGACCGGTTGGTTAAGCTCTGGCGCATGAGTGATACTAAGGCATGG GAAGTCGATACTTGCCGCGGCCATTTCCAGAATGCCTCCGCTGCTCTGTTCCACCCGCACCAAGACCTCATCCTT TCCGTCGGCGAAGATAAGACGATTCGCGCATGGGATCTCAACAAGCGTACATCCGTTCAGTCCTTTAAGCGCGAC CTTGATCGATTCTGGGTTATCGCTGCCCACCCCGAGATGAACCTGTTTGCCGCGGGTCATGACACTGGTGTTATG GTCTTCAAGCTCGAGCGAGAGCGCCCTGCGTCTGCTATCTACCAGAACCAGCTGTTTTACATCACAAAGGATAAG CACGTCAAGTCATATGACTTCAGCAAGAACGTCGAGTCGCCGCCGTTGCTTTCGCTGCGCAAGCTGGGTTCCCCA TGGGTCCCCCCACGTACCCTCTCTTACAATCCCGCTGAGCGTGCTATTTTGGTTACCACGCCCGCCGATAATGGA ACTTATGAACTGATTCATCTCCCCAGAGATGGTACTGGGGCTGTTGAGCCTACAGATGTTAAACGTGGACAGGCT ACTTCGGCAGTCTTCGTCGCCCGCAACCGCTTTGCCGTCTTCAGCCCCTCGACCCAACAGGTCGATATCAAGGAT CTTAGCAACTCCACAACGAAGACAATCAAGCCCCCAGCGGGCACAACCGACATCTACTTTGGTGGTACCGGATGT CTGCTCTTCATCACCCCTACACATGTTACTCTTTTCGACATTCAACAAAAGAAGCAGCTTGCAGAGCTTGCTGTC AGCGGGGTGAAGTATGTGGTGTGGTCTAACGATGGATTGTACTGCGCTTTGCTCAGTAAACACAACGTCACTATC GTGACCAAGACACTCGAGCAGGTTAGCACCTTGCACGAGACTATTCGCATCAAAAGTGCTACCTGGGATGACGCC GGTGTCCTGCTTTACTCCACCCTTAACCATGTGAAGTACTCCCTTCTCAACGGTGACAACGGTATCATCCGCACT CTTGACCAGACTGTATACCTCGTGCGCGTCAAGGGACGCAATGTCTATGCTCTTGACCGCAACGCCCAGCCACGC ATCTTGGAGATTGACCCGACTGAGTATCGTTTCAAGCTTGCCCTTGTGAAGCGAAATTACGACGAAATGCTTCAG ATTATCAAGACCTCGAGTTTGGTTGGCCAGAGCATCATCTCTTACCTGCAGAAGAAGGGTTACCCGGAGATTGCT CTACAATTCGTTCAAGACCCTCAGACTCGCTTTGACCTTGCCCTTGAATGTGGTAATCTCGAGGTCGCCAATGAA ATGGCACGGGAACTCGACCGTCCCAACTTCTGGACCAGACTTGGAGCTGAGGCATTGGCTCATGGTAACCATCAG ATCGTCGAAATGACTTACCAAAAGCAGCGTAGCTTCGACAAGCTCTCTTTCCTCTACCTCTCTACCGGTGACCAG GAGAAGCTTTCTCGTATGGCCAAGATCGCCGAACACCGTGGCGACTTCACCTCTCGTTTCCAAAACGCCATCTAC CGTGGCGACGTTGAGGACCGCATTCAGATGTTCAAGGAAGTGGACTTGTACCCTCTCGCCTATCTTACTGCCAAG TCAAATGGTCTGGTTGAAGAGGCCGAGTCCATTTTGGAGGCTGTTGGTCTCACCGAAGATCAGATTGTCCTACCT ACACTCGATCAACCTCTGAAGGTTCCTCACCCTATTGTACCCACTTTCAATTCCAATTGGCCCGTTAAGGCTGCC GGTCACTCGTCCTTCGAGAAGGCTCTTCTTGGAGAAGTTGGTGTTGCTGATGAGGAGGCTGGCGCTGTTGGATTC GAGATTGAGGAAGAGGAGCAAGAAGCTGATGTCGCCCGGGAAACCCTCGATGATGACGAAGAGGCAGTTTCCGGA TGGGATATGGGTGATGATGTTATTGTTGAGGAAGAAATCGACTTTGTCAATGTGGAAAGCGCCGAAGCTGGCGCC GGCAGTTCTGAGGCTGATTTGTGGGCTCGTAACTCCCCGCTGGCTGCTGATCACGTCGCCGCTGGCTCTTTTGAC ACTGCGATGCAGCTCTTGAACCGTCAAGTTGGTGCCGTTCAGTTCGCTCCTCTCAAGCCTCGCTTCCTCGAAGTT TACAAGGCGACCAAGACCTACCTCCCGGCGACTGCTGGTCTACCGCCTTTGATCAACTACGTGCGCCGGACCATC GACGAGACTGACTCCCGGAAGATGCTTCCCATCATTCCCCGAGACCTAGAGACCGTTGCCAGTGTTGACTTGCAA GAGGGTTATGCCGCTATGCGGTCCAACCGATTGGAGGAGGGCGTGGCAACATTCAAACGTATTCTTCACACTGTT CTCGTTAACACCGTGTCATCCGAAGCCGATGTGGATGAAGCGAAGAAGATCATTGCCACTGCTCGGGAATACATT CTCGCTATGTCGATCGAGCTCGAGCGCCGTACTCTCTCTACCAACTCCCCTGAGGATCTCAAGCGCAGCCTTGAA TTGTCTGCCTACTTCACAATTCCCAAGCTCGAGGTCGCTCACCGACAACTAGCGTTGATGGCTGCCATGAAGTTG GCCTTTGCCAACAAGAACTACGGCTCAGCCTTGAGCTTTGCCAACCGGATGCTGGCTAATGGAGGCTCCGCTAAA CTTTTGGAACAGGCCAAGAAGATCAAAGCTCAATGCGAACGCAATCCTCAAGACCAGATCGACATTGACTTCGAC CCCTTCGCCGAGTTCGATATCTGCGCTGCGTCCTTTACCCCTATCTATAGCGGCTCTCCCAGTGTCTCAGATCCC TTCACCGGCGCCAAATACCATCCCCAATACAAGGGAAGTGTCGACCGGATATCAGAGGTTACGGAGATTGGTGCC CCGGCCAGCGGCCTACGCCTGTTCGTCCCCAGTCAGTTTTAA
Transcript	>Pro_DTO377G3_2|g1241.t1 ATGCAGTCCTCCCCAAACATGCTCACCAAGTTTGAGTCCAAATCCTCCAGAGCTAAAGGAATCGCGTTCCATCCC AAACGACCATGGATCCTCGTCTCCCTTCACTCATCCACAATCCAACTGTGGGACTACCGTATGGGAACTCTTATC GACCGATTCGAAGAACACGATGGCCCGGTTCGCGGCGTTGACTTCCACCCAACCCAGCCCCTGTTTGTATCGGGA GGTGACGACTACAAGATCAAGGTCTGGAACTACCAGACTCGGAGGTGCTTGTTCACATTGAATGGCCACTTGGAT TATGTGCGAACAGTTTTCTTCCACCCCGAGCTGCCCTGGATTCTGTCTGCGTCCGACGACCAGACCATCCGAATC TGGAACTGGCAAAATCGGTCACTCATCTGTACGATGACCGGTCACAACCATTATGTTATGTGCGCTCAGTTCCAC CCCACCGAGGATCTCATTGCCTCGGCCTCGTTGGATCAGTCAGTTCGCATTTGGGATATCTCCGGCCTGCGGAAG AAGCACTCGGCCCCAACCTCGGTTTCCTTCGAAGACCAAATGGCAAGAGCCAACCCAAACCAAGCCGATATGTTC GGAAACACCGATGCAATCGTTAAATTTGTGCTGGAAGGTCATGACCGTGGTGTTAACTGGGTCTCGTTCCACCCC ACACTACCCTTGCTCGTGTCAGCCGGTGACGACCGGTTGGTTAAGCTCTGGCGCATGAGTGATACTAAGGCATGG GAAGTCGATACTTGCCGCGGCCATTTCCAGAATGCCTCCGCTGCTCTGTTCCACCCGCACCAAGACCTCATCCTT TCCGTCGGCGAAGATAAGACGATTCGCGCATGGGATCTCAACAAGCGTACATCCGTTCAGTCCTTTAAGCGCGAC CTTGATCGATTCTGGGTTATCGCTGCCCACCCCGAGATGAACCTGTTTGCCGCGGGTCATGACACTGGTGTTATG GTCTTCAAGCTCGAGCGAGAGCGCCCTGCGTCTGCTATCTACCAGAACCAGCTGTTTTACATCACAAAGGATAAG CACGTCAAGTCATATGACTTCAGCAAGAACGTCGAGTCGCCGCCGTTGCTTTCGCTGCGCAAGCTGGGTTCCCCA TGGGTCCCCCCACGTACCCTCTCTTACAATCCCGCTGAGCGTGCTATTTTGGTTACCACGCCCGCCGATAATGGA ACTTATGAACTGATTCATCTCCCCAGAGATGGTACTGGGGCTGTTGAGCCTACAGATGTTAAACGTGGACAGGCT ACTTCGGCAGTCTTCGTCGCCCGCAACCGCTTTGCCGTCTTCAGCCCCTCGACCCAACAGGTCGATATCAAGGAT CTTAGCAACTCCACAACGAAGACAATCAAGCCCCCAGCGGGCACAACCGACATCTACTTTGGTGGTACCGGATGT CTGCTCTTCATCACCCCTACACATGTTACTCTTTTCGACATTCAACAAAAGAAGCAGCTTGCAGAGCTTGCTGTC AGCGGGGTGAAGTATGTGGTGTGGTCTAACGATGGATTGTACTGCGCTTTGCTCAGTAAACACAACGTCACTATC GTGACCAAGACACTCGAGCAGGTTAGCACCTTGCACGAGACTATTCGCATCAAAAGTGCTACCTGGGATGACGCC GGTGTCCTGCTTTACTCCACCCTTAACCATGTGAAGTACTCCCTTCTCAACGGTGACAACGGTATCATCCGCACT CTTGACCAGACTGTATACCTCGTGCGCGTCAAGGGACGCAATGTCTATGCTCTTGACCGCAACGCCCAGCCACGC ATCTTGGAGATTGACCCGACTGAGTATCGTTTCAAGCTTGCCCTTGTGAAGCGAAATTACGACGAAATGCTTCAG ATTATCAAGACCTCGAGTTTGGTTGGCCAGAGCATCATCTCTTACCTGCAGAAGAAGGGTTACCCGGAGATTGCT CTACAATTCGTTCAAGACCCTCAGACTCGCTTTGACCTTGCCCTTGAATGTGGTAATCTCGAGGTCGCCAATGAA ATGGCACGGGAACTCGACCGTCCCAACTTCTGGACCAGACTTGGAGCTGAGGCATTGGCTCATGGTAACCATCAG ATCGTCGAAATGACTTACCAAAAGCAGCGTAGCTTCGACAAGCTCTCTTTCCTCTACCTCTCTACCGGTGACCAG GAGAAGCTTTCTCGTATGGCCAAGATCGCCGAACACCGTGGCGACTTCACCTCTCGTTTCCAAAACGCCATCTAC CGTGGCGACGTTGAGGACCGCATTCAGATGTTCAAGGAAGTGGACTTGTACCCTCTCGCCTATCTTACTGCCAAG TCAAATGGTCTGGTTGAAGAGGCCGAGTCCATTTTGGAGGCTGTTGGTCTCACCGAAGATCAGATTGTCCTACCT ACACTCGATCAACCTCTGAAGGTTCCTCACCCTATTGTACCCACTTTCAATTCCAATTGGCCCGTTAAGGCTGCC GGTCACTCGTCCTTCGAGAAGGCTCTTCTTGGAGAAGTTGGTGTTGCTGATGAGGAGGCTGGCGCTGTTGGATTC GAGATTGAGGAAGAGGAGCAAGAAGCTGATGTCGCCCGGGAAACCCTCGATGATGACGAAGAGGCAGTTTCCGGA TGGGATATGGGTGATGATGTTATTGTTGAGGAAGAAATCGACTTTGTCAATGTGGAAAGCGCCGAAGCTGGCGCC GGCAGTTCTGAGGCTGATTTGTGGGCTCGTAACTCCCCGCTGGCTGCTGATCACGTCGCCGCTGGCTCTTTTGAC ACTGCGATGCAGCTCTTGAACCGTCAAGTTGGTGCCGTTCAGTTCGCTCCTCTCAAGCCTCGCTTCCTCGAAGTT TACAAGGCGACCAAGACCTACCTCCCGGCGACTGCTGGTCTACCGCCTTTGATCAACTACGTGCGCCGGACCATC GACGAGACTGACTCCCGGAAGATGCTTCCCATCATTCCCCGAGACCTAGAGACCGTTGCCAGTGTTGACTTGCAA GAGGGTTATGCCGCTATGCGGTCCAACCGATTGGAGGAGGGCGTGGCAACATTCAAACGTATTCTTCACACTGTT CTCGTTAACACCGTGTCATCCGAAGCCGATGTGGATGAAGCGAAGAAGATCATTGCCACTGCTCGGGAATACATT CTCGCTATGTCGATCGAGCTCGAGCGCCGTACTCTCTCTACCAACTCCCCTGAGGATCTCAAGCGCAGCCTTGAA TTGTCTGCCTACTTCACAATTCCCAAGCTCGAGGTCGCTCACCGACAACTAGCGTTGATGGCTGCCATGAAGTTG GCCTTTGCCAACAAGAACTACGGCTCAGCCTTGAGCTTTGCCAACCGGATGCTGGCTAATGGAGGCTCCGCTAAA CTTTTGGAACAGGCCAAGAAGATCAAAGCTCAATGCGAACGCAATCCTCAAGACCAGATCGACATTGACTTCGAC CCCTTCGCCGAGTTCGATATCTGCGCTGCGTCCTTTACCCCTATCTATAGCGGCTCTCCCAGTGTCTCAGATCCC TTCACCGGCGCCAAATACCATCCCCAATACAAGGGAAGTGTCGACCGGATATCAGAGGTTACGGAGATTGGTGCC CCGGCCAGCGGCCTACGCCTGTTCGTCCCCAGTCAGTTTTAA
Gene	>Pro_DTO377G3_2|g1241.t1 ATGCAGTCCTCCCCAAACATGCTCACCAAGGTACACCCCCTCGGGCATCTTAATGCGCCATCGAACAATGGGACT CAATTGAAGATGCTAATCATTCTCTCAATTGTTTAGTTTGAGTCCAAATCCTCCAGAGCTAAAGGAATCGCGTTC CATCCCAAACGGTCAGTCAATCCCGCGGAGGGACACCTAACACCTCAAAGTGCTCAATCTGACCACAAAACAGAC CATGGATCCTCGTCTCCCTTCACTCATCCACAATCCAACTGTGGGACTACCGTATGGGAACTCTTATCGACCGAT TCGAAGAACACGATGGCCCGGTTCGCGGCGTTGACTTCCACCCAACCCAGCCCCTGTTTGTATCGGGAGGTGACG ACTACAAGATCAAGGTCTGGAACTACCAGACTCGGAGGTGCTTGTTCACATTGAATGGCCACTTGGATTATGTGC GAACAGTTTTCTTCCACCCCGAGCTGCCCTGGATTCTGTCTGCGTCCGACGACCAGACCATCCGAATCTGGAACT GGCAAAATCGGTCACTCAGTAAGATGCATTGGAGCTACCTGCAATAACATCGACTAACACGTCTACTCTTTTTAG TCTGTACGATGACCGGTCACAACCATTATGTTATGTGCGCTCAGTTCCACCCCACCGAGGATCTCATTGCCTCGG CCTCGTTGGATCAGTCAGTTCGCATTTGGGATATCTCCGGCCTGCGGAAGAAGCACTCGGCCCCAACCTCGGTTT CCTTCGAAGACCAAATGGCAAGAGCCAACCCAAACCAAGCCGATATGTTCGGAAACACCGATGCAATCGTTAAAT TTGTGCTGGAAGGTCATGACCGTGGTGTTAACTGGGTCTCGTTCCACCCCACACTACCCTTGCTCGTGTCAGCCG GTGACGACCGGTTGGTTAAGCTCTGGCGCATGAGTGATACTAAGGCATGGGAAGTCGATACTTGCCGCGGCCATT TCCAGAATGCCTCCGCTGCTCTGTTCCACCCGCACCAAGACCTCATCCTTTCCGTCGGCGAAGATAAGACGATTC GCGCATGGGATCTCAACAAGCGTACATCCGTTCAGTCCTTTAAGCGCGACCTTGATCGATTCTGGGTTATCGCTG CCCACCCCGAGATGAACCTGTTTGCCGCGGGTCATGACACTGGTGTTATGGTCTTCAAGCTCGAGCGAGAGCGCC CTGCGTCTGCTATCTACCAGAACCAGCTGTTTTACATCACAAAGGATAAGCACGTCAAGTCATATGACTTCAGCA AGAACGTCGAGTCGCCGCCGTTGCTTTCGCTGCGCAAGCTGGGTTCCCCATGGGTCCCCCCACGTACCCTCTCTT ACAATCCCGCTGAGCGTGCTATTTTGGTTACCACGCCCGCCGATAATGGAACTTATGAACTGATTCATCTCCCCA GAGATGGTACTGGGGCTGTTGAGCCTACAGATGTTAAACGTGGACAGGCTACTTCGGCAGTCTTCGTCGCCCGCA ACCGCTTTGCCGTCTTCAGCCCCTCGACCCAACAGGTCGATATCAAGGATCTTAGCAACTCCACAACGAAGACAA TCAAGCCCCCAGCGGGCACAACCGACATCTACTTTGGTGGTACCGGATGTCTGCTCTTCATCACCCCTACACATG TTACTCTTTTCGACATTCAACAAAAGAAGCAGCTTGCAGAGCTTGCTGTCAGCGGGGTGAAGTATGTGGTGTGGT CTAACGATGGATTGTACTGCGCTTTGCTCAGTAAACACAACGTCACTATCGTGACCAAGACACTCGAGCAGGTTA GCACCTTGCACGAGACTATTCGCATCAAAAGTGCTACCTGGGATGACGCCGGTGTCCTGCTTTACTCCACCCTTA ACCATGTGAAGTACTCCCTTCTCAACGGTGACAACGGTATCATCCGCACTCTTGACCAGACTGTATACCTCGTGC GCGTCAAGGGACGCAATGTCTATGCTCTTGACCGCAACGCCCAGCCACGCATCTTGGAGATTGACCCGACTGAGT ATCGTTTCAAGCTTGCCCTTGTGAAGCGAAATTACGACGAAATGCTTCAGATTATCAAGACCTCGAGTTTGGTTG GCCAGAGCATCATCTCTTACCTGCAGAAGAAGGGTTACCCGGAGATTGCTCTACAATTCGTTCAAGACCCTCAGA CTCGCTTTGACCTTGCCCTTGAATGTGGTAATCTCGAGGTCGCCAATGAAATGGCACGGGAACTCGACCGTCCCA ACTTCTGGACCAGACTTGGAGCTGAGGCATTGGCTCATGGTAACCATCAGATCGTCGAAATGACTTACCAAAAGC AGCGTAGCTTCGACAAGCTCTCTTTCCTCTACCTCTCTACCGGTGACCAGGAGAAGCTTTCTCGTATGGCCAAGA TCGCCGAACACCGTGGCGACTTCACCTCTCGTTTCCAAAACGCCATCTACCGTGGCGACGTTGAGGACCGCATTC AGATGTTCAAGGAAGTGGACTTGTGTATGTACAACCCTAGTGCCGATTGTTTCTTTCATACTAATTCTCGCAGAC CCTCTCGCCTATCTTACTGCCAAGTCAAATGGTCTGGTTGAAGAGGCCGAGTCCATTTTGGAGGCTGTTGGTCTC ACCGAAGATCAGATTGTCCTACCTACACTCGATCAACCTCTGAAGGTTCCTCACCCTATTGTACCCACTTTCAAT TCCAATTGGCCCGTTAAGGCTGCCGGTCACTCGTCCTTCGAGAAGGCTCTTCTTGGAGAAGTTGGTGTTGCTGAT GAGGAGGCTGGCGCTGTTGGATTCGAGATTGAGGAAGAGGAGCAAGAAGCTGATGTCGCCCGGGAAACCCTCGAT GATGACGAAGAGGCAGTTTCCGGATGGGATATGGGTGATGATGTTATTGTTGAGGAAGAAATCGACTTTGTCAAT GTGGAAAGCGCCGAAGCTGGCGCCGGCAGTTCTGAGGCTGATTTGTGGGCTCGTAACTCCCCGCTGGCTGCTGAT CACGTCGCCGCTGGCTCTTTTGACACTGCGATGCAGCTCTTGAACCGTCAAGTTGGTGCCGTTCAGTTCGCTCCT CTCAAGCCTCGCTTCCTCGAAGTTTACAAGGCGACCAAGACCTACCTCCCGGCGACTGCTGGTCTACCGCCTTTG ATCAACTACGTGCGCCGGACCATCGACGAGACTGACTCCCGGAAGATGCTTCCCATCATTCCCCGAGACCTAGAG ACCGTTGCCAGTGTTGACTTGCAAGAGGGTTATGCCGCTATGCGGTCCAACCGATTGGAGGAGGGCGTGGCAACA TTCAAACGTATTCTTCACACTGTTCTCGTTAACACCGTGTCATCCGAAGCCGATGTGGATGAAGCGAAGAAGATC ATTGCCACTGCTCGGGAATACATTCTCGCTATGTCGATCGAGCTCGAGCGCCGTACTCTCTCTACCAACTCCCCT GAGGATCTCAAGCGCAGCCTTGAATTGTCTGCCTACTTCACAATTCCCAAGCTCGAGGTCGCTCACCGACAACTA GCGTTGATGGCTGCCATGAAGTTGGCCTTTGCCAACAAGAACTACGGCTCAGCCTTGAGCTTTGCCAACCGGATG CTGGCTAATGGAGGCTCCGCTAAACTTTTGGAACAGGTAAGAATTCTTAAAGTTCAATTTTCCACTTATAATATA CCAATGCTAATTATGAAAAACAGGCCAAGAAGATCAAAGCTCAATGCGAACGCAATCCTCAAGACCAGATCGACA TTGACTTCGACCCCTTCGCCGAGTTCGATATCTGCGCTGCGTCCTTTACCCCTATCTATAGCGGCTCTCCCAGTG TCTCAGATCCCTTCACCGGCGCCAAATACCATCCCCAATACAAGGGAAGTGTCGACCGGATATCAGAGGTTACGG AGATTGGTGCCCCGGCCAGCGGCCTACGCCTGTTCGTCCCCAGTCAGTTTTAA