Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280

General Properties

Protein ID	Pro_DTO377G3_2|g1205.t1
Gene name
Location	scaffold_01:3179706..3182756
Strand	+
Gene length (bp)	3050
Transcript length (bp)	2820
Coding sequence length (bp)	2820
Protein length (aa)	940

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF01268	FTHFS	Formate--tetrahydrofolate ligase	1.6E-251	313	939
PF02882	THF_DHG_CYH_C	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	7.3E-66	127	289
PF00763	THF_DHG_CYH	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	5.7E-37	6	122

GO

GO Term	Description	Terminal node
GO:0055114	oxidation-reduction process	Yes
GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Yes
GO:0004329	formate-tetrahydrofolate ligase activity	Yes
GO:0005524	ATP binding	Yes
GO:0030554	adenyl nucleotide binding	No
GO:1901363	heterocyclic compound binding	No
GO:0032555	purine ribonucleotide binding	No
GO:0097159	organic cyclic compound binding	No
GO:0032553	ribonucleotide binding	No
GO:0003824	catalytic activity	No
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0043168	anion binding	No
GO:0016879	ligase activity, forming carbon-nitrogen bonds	No
GO:1901265	nucleoside phosphate binding	No
GO:0017076	purine nucleotide binding	No
GO:0097367	carbohydrate derivative binding	No
GO:0016491	oxidoreductase activity	No
GO:0008152	metabolic process	No
GO:0016874	ligase activity	No
GO:0008150	biological_process	No
GO:0008144	drug binding	No
GO:0003674	molecular_function	No
GO:0000166	nucleotide binding	No
GO:0043167	ion binding	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	No
GO:0005488	binding	No
GO:0036094	small molecule binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 12	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Genome-wide gene expression in conidia of Penicillium roqueforti during growth at various temperatures and for various amounts of time. Published in Punt et al., 2020.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Pro_DTO377G3_2|g1205.t1 MAAAKIDGTAIAKSIRQGLKSEIEQIQVTNPRFKPNLVIFQVGNRSDSSTYVRMKLKAAQEANIICTVINVPESS TELELIQEITKANNDPAVHGILVQLPVPSHMSEHAVTSSVADEKDVDGFGAINIGELAKRGGRPLFTPCTPLAVM ELLKASGVDPAGKEAVVLGRSDIVGSPVSYLLKNADATVTVCHSKTPDIARIVKTADIVVAAIGQTELVKGEWLK PGAVVIDVGINYKPDATKKSGERLVGDVDFESASQVASQITPVPGGVGPMTVAMLLKNVVGATKCYFEKQKDRHV TPLPIRILNPVPSDIAISRAQYPKPITQVATEVGIAPHELEPYGHTKAKISLSVLERLSHRRNGRYILVCGITPT PLGEGKSTTTLGLTQALGAHLNRISFANVRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITAANNL LAAAIETRMFHESTQKDAALYKRLVPASKGKREFKPIMFRRLKKLGIEKTNPDDLTEEEITRFARLDIDPETITW RRVLDVNDRHLRGITVGQAPTEKGLSRETGFDISVASECMAILALSNDLADMRERLGRMVVATSRSGDPVTCDDI GAGGALAALMKDAIKPNLMQSLEGTPVMVHAGPFANISIGASSAIADKLALKLAGTEPDEDHEAKTGFVVTEAGF DFTMGGERFFNIKCRSSGLVPDTVVIVATVRALKVHGGGPEIKPGAPLQEVYRTENVDILRKGCVNLRKHIANAK LYGVPVVVAINKFDTDTEAEIAVIKEEAIAAGAEDAVPANHWAEGGAGAVDLAKAVITASSKEKDFRLLYDLDGT IQERIERIGQAMYGAEKVEFSELAQKKVDAYTKQGFANLPICIAKTQYSLSHDPALKGAPTGFTVPIRDVRLAVG AGYLYALAADIQTIPGLPTAPGYLNVDIDPETGDIDGLF*
Coding	>Pro_DTO377G3_2|g1205.t1 ATGGCTGCCGCGAAGATTGATGGCACTGCCATCGCGAAGAGTATTCGCCAAGGGTTGAAGTCCGAGATCGAGCAG ATTCAAGTGACGAACCCCAGATTCAAGCCAAATCTGGTTATCTTCCAGGTCGGCAATCGGTCGGATTCAAGCACC TATGTGCGCATGAAGCTGAAGGCCGCCCAGGAGGCCAACATCATCTGCACCGTGATCAATGTTCCCGAATCGAGC ACCGAGTTGGAGCTCATCCAAGAGATCACCAAAGCCAACAATGACCCCGCTGTCCACGGTATCCTCGTTCAATTG CCCGTCCCAAGCCACATGTCCGAGCATGCGGTCACGTCGAGTGTTGCAGATGAGAAAGATGTTGATGGTTTCGGC GCAATCAATATCGGCGAGCTGGCGAAGCGAGGCGGTCGCCCGTTGTTCACTCCGTGCACCCCTCTCGCGGTTATG GAACTACTCAAGGCAAGCGGCGTAGACCCCGCCGGTAAGGAGGCAGTGGTACTGGGACGGAGTGACATCGTCGGC AGTCCGGTCAGCTATTTGCTTAAGAACGCCGATGCTACCGTTACTGTCTGCCACTCAAAGACACCGGATATTGCG CGCATTGTCAAGACCGCCGACATTGTTGTAGCGGCCATTGGCCAAACCGAGCTTGTGAAGGGTGAATGGTTGAAG CCCGGTGCTGTAGTTATTGATGTCGGTATCAATTACAAGCCTGATGCGACTAAGAAGTCCGGTGAGCGACTGGTT GGCGACGTGGACTTTGAGTCTGCTTCCCAGGTGGCCTCACAAATCACCCCCGTCCCCGGTGGTGTTGGTCCTATG ACAGTGGCTATGTTGTTGAAGAACGTGGTGGGTGCCACAAAGTGCTACTTCGAGAAACAGAAGGACCGCCACGTC ACTCCTCTTCCCATTCGCATACTAAATCCCGTGCCTTCCGACATTGCTATCTCGCGGGCCCAGTACCCCAAGCCC ATCACCCAGGTTGCCACCGAGGTCGGCATTGCCCCTCATGAGTTGGAGCCCTACGGCCACACCAAGGCCAAGATT AGTCTGAGTGTGCTGGAACGCCTCTCCCATCGCCGCAACGGAAGATACATCTTGGTTTGCGGTATCACACCCACC CCTCTTGGTGAGGGCAAGTCCACTACCACACTAGGTCTCACTCAAGCACTTGGTGCCCACCTGAACCGCATTTCC TTTGCCAACGTCCGACAGCCCAGCCAAGGCCCCACATTCGGCATCAAGGGTGGTGCTGCTGGTGGAGGCTACAGT CAGGTTATTCCTATGGACGAGTTCAATCTCCACCTCACGGGTGACATCCACGCCATCACCGCCGCGAACAACCTT CTCGCTGCGGCTATTGAGACTCGCATGTTCCACGAGTCCACCCAGAAAGATGCAGCTCTCTACAAGCGTCTTGTC CCTGCCAGCAAGGGCAAGCGTGAATTCAAGCCCATCATGTTCCGACGTCTGAAGAAGCTGGGCATTGAGAAGACC AACCCAGACGATCTCACTGAGGAGGAAATCACCCGCTTTGCCCGCCTAGATATCGACCCAGAGACCATCACTTGG CGCCGTGTTCTCGATGTCAATGACCGTCATCTACGTGGTATCACTGTCGGCCAGGCCCCTACCGAGAAGGGCCTG TCTCGTGAGACTGGCTTCGATATCTCCGTCGCTAGTGAGTGCATGGCCATTCTTGCCTTGAGTAACGATTTGGCG GATATGCGTGAGCGACTGGGCCGTATGGTTGTTGCTACTTCTAGAAGCGGCGACCCCGTGACTTGCGACGACATT GGTGCCGGTGGTGCCCTTGCCGCCTTGATGAAGGATGCCATTAAGCCAAATTTGATGCAGAGTTTGGAAGGCACT CCTGTGATGGTGCACGCTGGTCCCTTTGCCAACATCAGTATTGGCGCCAGCTCTGCCATCGCCGATAAGCTTGCC CTGAAGCTTGCCGGTACCGAGCCTGATGAGGACCATGAAGCCAAGACCGGTTTCGTGGTCACCGAGGCTGGCTTC GACTTCACAATGGGTGGTGAGCGCTTCTTTAACATCAAGTGCCGCTCCTCTGGTCTGGTTCCGGACACCGTCGTT ATTGTGGCTACTGTCCGTGCGCTGAAGGTTCACGGCGGCGGCCCCGAGATCAAGCCCGGTGCCCCTCTGCAGGAG GTCTACCGCACCGAGAATGTGGATATTCTCCGCAAGGGTTGTGTTAACCTGCGGAAGCACATTGCTAACGCCAAG CTGTACGGCGTCCCGGTGGTGGTGGCTATCAATAAGTTCGACACCGATACCGAGGCTGAAATTGCTGTCATCAAG GAGGAGGCGATCGCCGCTGGTGCCGAGGATGCCGTCCCTGCCAACCATTGGGCTGAGGGTGGAGCCGGCGCTGTT GATCTGGCCAAGGCTGTCATAACCGCCAGCTCCAAGGAGAAGGACTTCCGGCTCCTCTACGACCTGGATGGTACT ATCCAGGAGCGCATCGAGCGCATCGGCCAGGCCATGTATGGCGCTGAGAAGGTTGAGTTCAGTGAATTGGCTCAG AAGAAGGTCGACGCCTACACCAAGCAAGGATTCGCGAACCTGCCGATCTGTATCGCCAAGACTCAGTACTCACTC AGTCACGACCCAGCCCTCAAGGGTGCCCCCACCGGCTTCACTGTGCCCATTCGGGATGTCAGATTGGCCGTGGGC GCTGGATACCTCTACGCTCTGGCCGCCGATATCCAGACCATTCCCGGACTACCCACTGCCCCCGGCTACCTTAAT GTGGATATCGACCCCGAGACTGGCGATATTGACGGGCTGTTCTAG
Transcript	>Pro_DTO377G3_2|g1205.t1 ATGGCTGCCGCGAAGATTGATGGCACTGCCATCGCGAAGAGTATTCGCCAAGGGTTGAAGTCCGAGATCGAGCAG ATTCAAGTGACGAACCCCAGATTCAAGCCAAATCTGGTTATCTTCCAGGTCGGCAATCGGTCGGATTCAAGCACC TATGTGCGCATGAAGCTGAAGGCCGCCCAGGAGGCCAACATCATCTGCACCGTGATCAATGTTCCCGAATCGAGC ACCGAGTTGGAGCTCATCCAAGAGATCACCAAAGCCAACAATGACCCCGCTGTCCACGGTATCCTCGTTCAATTG CCCGTCCCAAGCCACATGTCCGAGCATGCGGTCACGTCGAGTGTTGCAGATGAGAAAGATGTTGATGGTTTCGGC GCAATCAATATCGGCGAGCTGGCGAAGCGAGGCGGTCGCCCGTTGTTCACTCCGTGCACCCCTCTCGCGGTTATG GAACTACTCAAGGCAAGCGGCGTAGACCCCGCCGGTAAGGAGGCAGTGGTACTGGGACGGAGTGACATCGTCGGC AGTCCGGTCAGCTATTTGCTTAAGAACGCCGATGCTACCGTTACTGTCTGCCACTCAAAGACACCGGATATTGCG CGCATTGTCAAGACCGCCGACATTGTTGTAGCGGCCATTGGCCAAACCGAGCTTGTGAAGGGTGAATGGTTGAAG CCCGGTGCTGTAGTTATTGATGTCGGTATCAATTACAAGCCTGATGCGACTAAGAAGTCCGGTGAGCGACTGGTT GGCGACGTGGACTTTGAGTCTGCTTCCCAGGTGGCCTCACAAATCACCCCCGTCCCCGGTGGTGTTGGTCCTATG ACAGTGGCTATGTTGTTGAAGAACGTGGTGGGTGCCACAAAGTGCTACTTCGAGAAACAGAAGGACCGCCACGTC ACTCCTCTTCCCATTCGCATACTAAATCCCGTGCCTTCCGACATTGCTATCTCGCGGGCCCAGTACCCCAAGCCC ATCACCCAGGTTGCCACCGAGGTCGGCATTGCCCCTCATGAGTTGGAGCCCTACGGCCACACCAAGGCCAAGATT AGTCTGAGTGTGCTGGAACGCCTCTCCCATCGCCGCAACGGAAGATACATCTTGGTTTGCGGTATCACACCCACC CCTCTTGGTGAGGGCAAGTCCACTACCACACTAGGTCTCACTCAAGCACTTGGTGCCCACCTGAACCGCATTTCC TTTGCCAACGTCCGACAGCCCAGCCAAGGCCCCACATTCGGCATCAAGGGTGGTGCTGCTGGTGGAGGCTACAGT CAGGTTATTCCTATGGACGAGTTCAATCTCCACCTCACGGGTGACATCCACGCCATCACCGCCGCGAACAACCTT CTCGCTGCGGCTATTGAGACTCGCATGTTCCACGAGTCCACCCAGAAAGATGCAGCTCTCTACAAGCGTCTTGTC CCTGCCAGCAAGGGCAAGCGTGAATTCAAGCCCATCATGTTCCGACGTCTGAAGAAGCTGGGCATTGAGAAGACC AACCCAGACGATCTCACTGAGGAGGAAATCACCCGCTTTGCCCGCCTAGATATCGACCCAGAGACCATCACTTGG CGCCGTGTTCTCGATGTCAATGACCGTCATCTACGTGGTATCACTGTCGGCCAGGCCCCTACCGAGAAGGGCCTG TCTCGTGAGACTGGCTTCGATATCTCCGTCGCTAGTGAGTGCATGGCCATTCTTGCCTTGAGTAACGATTTGGCG GATATGCGTGAGCGACTGGGCCGTATGGTTGTTGCTACTTCTAGAAGCGGCGACCCCGTGACTTGCGACGACATT GGTGCCGGTGGTGCCCTTGCCGCCTTGATGAAGGATGCCATTAAGCCAAATTTGATGCAGAGTTTGGAAGGCACT CCTGTGATGGTGCACGCTGGTCCCTTTGCCAACATCAGTATTGGCGCCAGCTCTGCCATCGCCGATAAGCTTGCC CTGAAGCTTGCCGGTACCGAGCCTGATGAGGACCATGAAGCCAAGACCGGTTTCGTGGTCACCGAGGCTGGCTTC GACTTCACAATGGGTGGTGAGCGCTTCTTTAACATCAAGTGCCGCTCCTCTGGTCTGGTTCCGGACACCGTCGTT ATTGTGGCTACTGTCCGTGCGCTGAAGGTTCACGGCGGCGGCCCCGAGATCAAGCCCGGTGCCCCTCTGCAGGAG GTCTACCGCACCGAGAATGTGGATATTCTCCGCAAGGGTTGTGTTAACCTGCGGAAGCACATTGCTAACGCCAAG CTGTACGGCGTCCCGGTGGTGGTGGCTATCAATAAGTTCGACACCGATACCGAGGCTGAAATTGCTGTCATCAAG GAGGAGGCGATCGCCGCTGGTGCCGAGGATGCCGTCCCTGCCAACCATTGGGCTGAGGGTGGAGCCGGCGCTGTT GATCTGGCCAAGGCTGTCATAACCGCCAGCTCCAAGGAGAAGGACTTCCGGCTCCTCTACGACCTGGATGGTACT ATCCAGGAGCGCATCGAGCGCATCGGCCAGGCCATGTATGGCGCTGAGAAGGTTGAGTTCAGTGAATTGGCTCAG AAGAAGGTCGACGCCTACACCAAGCAAGGATTCGCGAACCTGCCGATCTGTATCGCCAAGACTCAGTACTCACTC AGTCACGACCCAGCCCTCAAGGGTGCCCCCACCGGCTTCACTGTGCCCATTCGGGATGTCAGATTGGCCGTGGGC GCTGGATACCTCTACGCTCTGGCCGCCGATATCCAGACCATTCCCGGACTACCCACTGCCCCCGGCTACCTTAAT GTGGATATCGACCCCGAGACTGGCGATATTGACGGGCTGTTCTAG
Gene	>Pro_DTO377G3_2|g1205.t1 ATGGCTGCCGCGAAGATTGATGGCACTGCCATCGCGAAGAGTATTCGCCAAGGGTTGAAGTCCGAGATCGAGCAG ATTCAAGTGACGAACCCCAGATTCAAGCCAAATCTGGTTATCTTCCAGGGTAAGCGTGACCCGCTCCGAGCATGA ATACATGTAATGTAGTGTTGAATACTAACATGACGATTCTTATCTAGTCGGCAATCGGTCGGATTCAAGTTGGTT TACCTACGAATAGTATTGAAGATCTTGCGGACTAATTTTACTTAGGCACCTATGTGCGCATGAAGCTGAAGGCCG CCCAGGAGGTATGACTCGTTGTTCGGGATATCCGAGGCATTCTCTGACCTTATTCCTAGGCCAACATCATCTGCA CCGTGATCAATGTTCCCGAATCGAGCACCGAGTTGGAGCTCATCCAAGAGATCACCAAAGCCAACAATGACCCCG CTGTCCACGGTATCCTCGTTCAATTGCCCGTCCCAAGCCACATGTCCGAGCATGCGGTCACGTCGAGTGTTGCAG ATGAGAAAGATGTTGATGGTTTCGGCGCAATCAATATCGGCGAGCTGGCGAAGCGAGGCGGTCGCCCGTTGTTCA CTCCGTGCACCCCTCTCGCGGTTATGGAACTACTCAAGGCAAGCGGCGTAGACCCCGCCGGTAAGGAGGCAGTGG TACTGGGACGGAGTGACATCGTCGGCAGTCCGGTCAGCTATTTGCTTAAGAACGCCGATGCTACCGTTACTGTCT GCCACTCAAAGACACCGGATATTGCGCGCATTGTCAAGACCGCCGACATTGTTGTAGCGGCCATTGGCCAAACCG AGCTTGTGAAGGGTGAATGGTTGAAGCCCGGTGCTGTAGTTATTGATGTCGGTATCAATTACAAGCCTGATGCGA CTAAGAAGTCCGGTGAGCGACTGGTTGGCGACGTGGACTTTGAGTCTGCTTCCCAGGTGGCCTCACAAATCACCC CCGTCCCCGGTGGTGTTGGTCCTATGACAGTGGCTATGTTGTTGAAGAACGTGGTGGGTGCCACAAAGTGCTACT TCGAGAAACAGAAGGACCGCCACGTCACTCCTCTTCCCATTCGCATACTAAATCCCGTGCCTTCCGACATTGCTA TCTCGCGGGCCCAGTACCCCAAGCCCATCACCCAGGTTGCCACCGAGGTCGGCATTGCCCCTCATGAGTTGGAGC CCTACGGCCACACCAAGGCCAAGATTAGTCTGAGTGTGCTGGAACGCCTCTCCCATCGCCGCAACGGAAGATACA TCTTGGTTTGCGGTATCACACCCACCCCTCTTGGTGAGGGCAAGTCCACTACCACACTAGGTCTCACTCAAGCAC TTGGTGCCCACCTGAACCGCATTTCCTTTGCCAACGTCCGACAGCCCAGCCAAGGCCCCACATTCGGCATCAAGG GTGGTGCTGCTGGTGGAGGCTACAGTCAGGTTATTCCTATGGACGAGTTCAATCTCCACCTCACGGGTGACATCC ACGCCATCACCGCCGCGAACAACCTTCTCGCTGCGGCTATTGAGACTCGCATGTTCCACGAGTCCACCCAGAAAG ATGCAGCTCTCTACAAGCGTCTTGTCCCTGCCAGCAAGGGCAAGCGTGAATTCAAGCCCATCATGTTCCGACGTC TGAAGAAGCTGGGCATTGAGAAGACCAACCCAGACGATCTCACTGAGGAGGAAATCACCCGCTTTGCCCGCCTAG ATATCGACCCAGAGACCATCACTTGGCGCCGTGTTCTCGATGTCAATGACCGTCATCTACGTGGTATCACTGTCG GCCAGGCCCCTACCGAGAAGGGCCTGTCTCGTGAGACTGGCTTCGATATCTCCGTCGCTAGTGAGTGCATGGCCA TTCTTGCCTTGAGTAACGATTTGGCGGATATGCGTGAGCGACTGGGCCGTATGGTTGTTGCTACTTCTAGAAGCG GCGACCCCGTGACTTGCGACGACATTGGTGCCGGTGGTGCCCTTGCCGCCTTGATGAAGGATGCCATTAAGCCAA ATTTGATGCAGAGTTTGGAAGGCACTCCTGTGATGGTGCACGCTGGTCCCTTTGCCAACATCAGTATTGGCGCCA GCTCTGCCATCGCCGATAAGCTTGCCCTGAAGCTTGCCGGTACCGAGCCTGATGAGGACCATGAAGCCAAGACCG GTTTCGTGGTCACCGAGGCTGGCTTCGACTTCACAATGGGTGGTGAGCGCTTCTTTAACATCAAGTGCCGCTCCT CTGGTCTGGTTCCGGACACCGTCGTTATTGTGGCTACTGTCCGTGCGCTGAAGGTTCACGGCGGCGGCCCCGAGA TCAAGCCCGGTGCCCCTCTGCAGGAGGTCTACCGCACCGAGAATGTGGATATTCTCCGCAAGGGTTGTGTTAACC TGCGGAAGCACATTGCTAACGCCAAGCTGTACGGCGTCCCGGTGGTGGTGGCTATCAATAAGTTCGACACCGATA CCGAGGCTGAAATTGCTGTCATCAAGGAGGAGGCGATCGCCGCTGGTGCCGAGGATGCCGTCCCTGCCAACCATT GGGCTGAGGGTGGAGCCGGCGCTGTTGATCTGGCCAAGGCTGTCATAACCGCCAGCTCCAAGGAGAAGGACTTCC GGCTCCTCTACGACCTGGATGGTACTATCCAGGAGCGCATCGAGCGCATCGGCCAGGCCATGTATGGCGCTGAGA AGGTTGAGTTCAGTGAATTGGCTCAGAAGAAGGTCGACGCCTACACCAAGCAAGGATTCGCGAACCTGCCGATCT GTATCGCCAAGACTCAGTACTCACTCAGTCACGACCCAGCCCTCAAGGGTGCCCCCACCGGCTTCACTGTGCCCA TTCGGGATGTCAGATTGGCCGTGGGCGCTGGATACCTGTAAGTTTTTATCCCCGCATTTTGTGGGAATTCGTCAC GCTAACATAGCTATAGCTACGCTCTGGCCGCCGATATCCAGACCATTCCCGGACTACCCACTGCCCCCGGCTACC TTAATGTGGATATCGACCCCGAGACTGGCGATATTGACGGGCTGTTCTAG