Fungal Genomics

at Utrecht University

PFAM Domain


General information

PFAM domainPF14765
Short namePS-DH
Long namePolyketide synthase dehydratase
Proteins with at least one of this domain17
Total domain count17
More informationPFAM website

Proteins with this PFAM domain

Note: all PFAM domains are shown for these proteins
Short name Long name E-value Start End Name
protein ID PFAM
Pro_DTO377G3_2|g2030.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 5.0E-68 41 290
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 1.0E-40 299 415
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 6.4E-15 418 515
PF00698 Acyl_transf_1 Acyl transferase domain 1.8E-46 577 878
PF14765 PS-DH Polyketide synthase dehydratase 2.2E-57 966 1280
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 3.4E-14 1985 2089
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 8.9E-16 2027 2160
PF08659 KR KR domain 2.4E-60 2184 2361
PF00106 adh_short short chain dehydrogenase 1.0E-12 2187 2361
PF00550 PP-binding Phosphopantetheine attachment site 2.6E-08 2478 2543
Pro_DTO377G3_2|g2032.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 3.9E-73 9 259
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 1.2E-28 269 388
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 2.2E-14 393 491
PF00698 Acyl_transf_1 Acyl transferase domain 2.3E-38 550 870
PF14765 PS-DH Polyketide synthase dehydratase 5.8E-48 940 1240
PF01209 Ubie_methyltran ubiE/COQ5 methyltransferase family 4.3E-09 1406 1532
PF13489 Methyltransf_23 Methyltransferase domain 1.1E-14 1413 1573
PF13847 Methyltransf_31 Methyltransferase domain 5.0E-13 1414 1528
PF13649 Methyltransf_25 Methyltransferase domain 2.3E-14 1417 1517
PF08241 Methyltransf_11 Methyltransferase domain 8.1E-14 1418 1521
PF08242 Methyltransf_12 Methyltransferase domain 1.9E-18 1418 1519
PF08659 KR KR domain 5.3E-51 2107 2281
PF00106 adh_short short chain dehydrogenase 4.4E-12 2110 2280
PF00668 Condensation Condensation domain 3.4E-67 2608 3038
PF00501 AMP-binding AMP-binding enzyme 2.6E-75 3072 3480
PF00550 PP-binding Phosphopantetheine attachment site 7.5E-10 3608 3673
PF01370 Epimerase NAD dependent epimerase/dehydratase family 8.4E-14 3730 3951
PF01073 3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family 5.7E-08 3731 3917
PF07993 NAD_binding_4 Male sterility protein 1.2E-35 3732 3956
Pro_DTO377G3_2|g319.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 1.7E-68 21 272
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 2.7E-37 281 397
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 1.0E-14 401 489
PF00698 Acyl_transf_1 Acyl transferase domain 4.0E-50 552 868
PF14765 PS-DH Polyketide synthase dehydratase 4.9E-46 935 1251
PF08240 ADH_N Alcohol dehydrogenase GroES-like domain 1.7E-06 1534 1596
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 1.3E-12 1651 1755
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 4.5E-15 1692 1826
PF08659 KR KR domain 7.3E-64 1850 2028
PF00106 adh_short short chain dehydrogenase 6.4E-16 1853 2011
PF13561 adh_short_C2 Enoyl-(Acyl carrier protein) reductase 2.3E-11 1859 2011
PF00550 PP-binding Phosphopantetheine attachment site 5.9E-06 2142 2206
Pro_DTO377G3_2|g3680.t1 PF16073 SAT Starter unit:ACP transacylase in aflatoxin biosynthesis 1.3E-10 86 259
PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 7.4E-76 404 646
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 2.2E-36 654 770
PF00698 Acyl_transf_1 Acyl transferase domain 4.0E-18 981 1199
PF14765 PS-DH Polyketide synthase dehydratase 5.5E-28 1335 1609
PF00550 PP-binding Phosphopantetheine attachment site 5.3E-12 1656 1721
PF18558 HTH_51 Helix-turn-helix domain 6.0E-18 1777 1852
PF02636 Methyltransf_28 Putative S-adenosyl-L-methionine-dependent methyltransferase 1.5E-06 1938 2006
PF13489 Methyltransf_23 Methyltransferase domain 1.2E-11 1939 2112
PF13847 Methyltransf_31 Methyltransferase domain 7.1E-09 1954 2066
PF13649 Methyltransf_25 Methyltransferase domain 4.7E-11 1957 2059
PF08241 Methyltransf_11 Methyltransferase domain 2.4E-09 1958 2062
PF08242 Methyltransf_12 Methyltransferase domain 4.7E-19 1958 2061
PF07859 Abhydrolase_3 alpha/beta hydrolase fold 4.0E-09 2182 2300
PF00326 Peptidase_S9 Prolyl oligopeptidase family 2.8E-07 2394 2483
Pro_DTO377G3_2|g4183.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 3.7E-65 22 271
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 3.7E-33 281 394
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 8.9E-10 399 486
PF00698 Acyl_transf_1 Acyl transferase domain 1.1E-43 620 950
PF14765 PS-DH Polyketide synthase dehydratase 9.1E-63 1014 1332
PF05401 NodS Nodulation protein S (NodS) 2.7E-05 1508 1633
PF13489 Methyltransf_23 Methyltransferase domain 3.9E-10 1516 1685
PF13847 Methyltransf_31 Methyltransferase domain 3.7E-10 1517 1636
PF13649 Methyltransf_25 Methyltransferase domain 5.7E-10 1522 1629
PF08241 Methyltransf_11 Methyltransferase domain 7.5E-08 1523 1633
PF08242 Methyltransf_12 Methyltransferase domain 4.8E-19 1523 1631
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 1.2E-09 2058 2152
PF08659 KR KR domain 1.1E-59 2253 2430
PF00106 adh_short short chain dehydrogenase 7.6E-10 2257 2403
PF00550 PP-binding Phosphopantetheine attachment site 4.1E-06 2550 2612
Pro_DTO377G3_2|g4462.t1 PF16073 SAT Starter unit:ACP transacylase in aflatoxin biosynthesis 5.8E-08 15 165
PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 6.3E-73 388 629
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 4.4E-36 637 753
PF00698 Acyl_transf_1 Acyl transferase domain 4.4E-14 915 1139
PF14765 PS-DH Polyketide synthase dehydratase 1.6E-24 1324 1599
PF00550 PP-binding Phosphopantetheine attachment site 1.1E-12 1657 1721
PF18558 HTH_51 Helix-turn-helix domain 9.0E-20 1784 1863
PF13489 Methyltransf_23 Methyltransferase domain 6.4E-08 1947 2115
PF13847 Methyltransf_31 Methyltransferase domain 3.1E-06 1958 2070
PF13649 Methyltransf_25 Methyltransferase domain 2.3E-10 1962 2062
PF08241 Methyltransf_11 Methyltransferase domain 2.1E-09 1963 2065
PF08242 Methyltransf_12 Methyltransferase domain 1.2E-15 1963 2064
PF07859 Abhydrolase_3 alpha/beta hydrolase fold 2.2E-09 2188 2308
PF00326 Peptidase_S9 Prolyl oligopeptidase family 9.2E-08 2403 2492
PF01738 DLH Dienelactone hydrolase family 3.3E-04 2418 2491
Pro_DTO377G3_2|g4740.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 3.1E-72 3 253
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 9.0E-29 262 383
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 5.9E-17 396 504
PF00698 Acyl_transf_1 Acyl transferase domain 5.2E-46 544 860
PF14765 PS-DH Polyketide synthase dehydratase 5.8E-47 932 1229
PF01209 Ubie_methyltran ubiE/COQ5 methyltransferase family 4.4E-06 1389 1517
PF13489 Methyltransf_23 Methyltransferase domain 4.6E-08 1390 1523
PF13649 Methyltransf_25 Methyltransferase domain 2.0E-10 1407 1507
PF08241 Methyltransf_11 Methyltransferase domain 1.3E-09 1409 1510
PF08242 Methyltransf_12 Methyltransferase domain 1.0E-18 1409 1509
PF08659 KR KR domain 1.1E-47 2093 2267
PF00106 adh_short short chain dehydrogenase 2.9E-09 2097 2248
PF00550 PP-binding Phosphopantetheine attachment site 3.6E-07 2387 2447
PF00668 Condensation Condensation domain 2.7E-51 2548 2973
PF00501 AMP-binding AMP-binding enzyme 1.0E-77 3012 3422
PF00550 PP-binding Phosphopantetheine attachment site 4.8E-10 3539 3604
PF01370 Epimerase NAD dependent epimerase/dehydratase family 3.4E-09 3642 3800
PF07993 NAD_binding_4 Male sterility protein 1.5E-25 3644 3809
Pro_DTO377G3_2|g5789.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 3.4E-64 17 268
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 4.7E-37 278 391
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 3.0E-18 395 512
PF00698 Acyl_transf_1 Acyl transferase domain 1.3E-56 546 873
PF14765 PS-DH Polyketide synthase dehydratase 1.7E-57 930 1227
PF08240 ADH_N Alcohol dehydrogenase GroES-like domain 1.5E-04 1653 1712
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 2.2E-14 1772 1890
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 2.3E-10 1809 1950
PF08659 KR KR domain 8.4E-47 1976 2156
PF00106 adh_short short chain dehydrogenase 9.0E-11 1978 2146
Pro_DTO377G3_2|g6432.t1 PF16073 SAT Starter unit:ACP transacylase in aflatoxin biosynthesis 4.2E-84 8 244
PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 2.5E-79 374 623
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 4.7E-33 631 750
PF00698 Acyl_transf_1 Acyl transferase domain 5.3E-43 910 1212
PF14765 PS-DH Polyketide synthase dehydratase 2.1E-12 1302 1593
PF00550 PP-binding Phosphopantetheine attachment site 9.4E-10 1645 1706
PF00550 PP-binding Phosphopantetheine attachment site 3.2E-12 1764 1827
PF00975 Thioesterase Thioesterase domain 1.2E-21 1881 1986
Pro_DTO377G3_2|g6970.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 1.5E-68 22 272
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 1.5E-37 281 395
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 2.4E-18 399 519
PF00698 Acyl_transf_1 Acyl transferase domain 1.1E-55 547 844
PF14765 PS-DH Polyketide synthase dehydratase 2.1E-53 934 1235
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 2.2E-11 1754 1860
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 2.1E-15 1792 1930
PF08659 KR KR domain 6.5E-51 1955 2132
PF00106 adh_short short chain dehydrogenase 1.3E-06 1957 2114
Pro_DTO377G3_2|g744.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 8.1E-30 14 177
PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 5.1E-14 179 240
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 7.6E-30 249 364
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 4.7E-24 368 482
PF00698 Acyl_transf_1 Acyl transferase domain 2.5E-57 505 828
PF14765 PS-DH Polyketide synthase dehydratase 2.6E-65 876 1156
PF13489 Methyltransf_23 Methyltransferase domain 2.3E-11 1311 1482
PF13847 Methyltransf_31 Methyltransferase domain 3.7E-07 1322 1437
PF13649 Methyltransf_25 Methyltransferase domain 2.7E-09 1326 1429
PF08241 Methyltransf_11 Methyltransferase domain 2.2E-07 1327 1432
PF08242 Methyltransf_12 Methyltransferase domain 3.5E-17 1327 1431
PF08240 ADH_N Alcohol dehydrogenase GroES-like domain 4.6E-07 1717 1777
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 5.7E-15 1836 1942
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 2.1E-12 1877 2011
PF08659 KR KR domain 1.4E-57 2039 2216
PF00106 adh_short short chain dehydrogenase 4.6E-08 2042 2198
PF00550 PP-binding Phosphopantetheine attachment site 1.0E-04 2354 2401
Pro_DTO377G3_2|g7828.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 3.1E-74 39 288
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 2.4E-39 297 414
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 4.5E-16 417 501
PF00698 Acyl_transf_1 Acyl transferase domain 2.1E-60 563 892
PF14765 PS-DH Polyketide synthase dehydratase 3.8E-48 949 1266
PF01209 Ubie_methyltran ubiE/COQ5 methyltransferase family 1.3E-05 1431 1562
PF13489 Methyltransf_23 Methyltransferase domain 3.7E-09 1436 1602
PF13649 Methyltransf_25 Methyltransferase domain 2.3E-11 1442 1548
PF08241 Methyltransf_11 Methyltransferase domain 1.6E-09 1444 1551
PF08242 Methyltransf_12 Methyltransferase domain 4.3E-20 1444 1549
PF08240 ADH_N Alcohol dehydrogenase GroES-like domain 1.9E-05 1858 1914
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 5.5E-13 1975 2103
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 4.1E-10 2013 2150
PF08659 KR KR domain 2.2E-49 2174 2354
PF00106 adh_short short chain dehydrogenase 1.3E-15 2177 2335
PF13561 adh_short_C2 Enoyl-(Acyl carrier protein) reductase 7.4E-07 2183 2334
PF00550 PP-binding Phosphopantetheine attachment site 1.1E-06 2473 2538
Pro_DTO377G3_2|g7919.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 4.9E-65 21 267
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 1.8E-26 276 388
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 2.1E-26 391 507
PF00698 Acyl_transf_1 Acyl transferase domain 7.6E-61 531 850
PF14765 PS-DH Polyketide synthase dehydratase 6.9E-63 900 1179
PF01209 Ubie_methyltran ubiE/COQ5 methyltransferase family 5.7E-05 1348 1480
PF13489 Methyltransf_23 Methyltransferase domain 8.5E-11 1361 1524
PF13847 Methyltransf_31 Methyltransferase domain 2.8E-08 1362 1483
PF13649 Methyltransf_25 Methyltransferase domain 2.1E-10 1367 1471
PF08241 Methyltransf_11 Methyltransferase domain 2.8E-09 1368 1474
PF08242 Methyltransf_12 Methyltransferase domain 2.6E-16 1368 1473
PF08240 ADH_N Alcohol dehydrogenase GroES-like domain 1.3E-04 1763 1820
PF00107 ADH_zinc_N Zinc-binding dehydrogenase 1.5E-14 1864 1960
PF13602 ADH_zinc_N_2 Zinc-binding dehydrogenase 1.5E-14 1904 2039
PF08659 KR KR domain 2.9E-58 2063 2238
PF00106 adh_short short chain dehydrogenase 2.5E-09 2066 2229
PF00550 PP-binding Phosphopantetheine attachment site 3.1E-04 2394 2432
Pro_DTO377G3_2|g8038.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 8.6E-72 24 274
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 3.2E-38 283 400
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 1.4E-14 403 540
PF00698 Acyl_transf_1 Acyl transferase domain 7.5E-44 570 846
PF14765 PS-DH Polyketide synthase dehydratase 9.9E-60 984 1295
PF08241 Methyltransf_11 Methyltransferase domain 8.6E-05 1464 1571
PF08242 Methyltransf_12 Methyltransferase domain 1.7E-07 1464 1570
PF08659 KR KR domain 6.8E-60 2173 2350
PF00106 adh_short short chain dehydrogenase 1.1E-12 2177 2331
PF13561 adh_short_C2 Enoyl-(Acyl carrier protein) reductase 3.3E-08 2182 2321
Pro_DTO377G3_2|g8063.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 8.9E-75 10 260
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 7.0E-30 270 394
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 9.0E-11 413 517
PF00698 Acyl_transf_1 Acyl transferase domain 3.3E-46 557 884
PF14765 PS-DH Polyketide synthase dehydratase 7.5E-54 951 1247
PF13489 Methyltransf_23 Methyltransferase domain 2.1E-10 1418 1580
PF01209 Ubie_methyltran ubiE/COQ5 methyltransferase family 9.2E-05 1419 1537
PF13847 Methyltransf_31 Methyltransferase domain 1.4E-11 1423 1533
PF05401 NodS Nodulation protein S (NodS) 5.1E-05 1424 1546
PF13649 Methyltransf_25 Methyltransferase domain 1.5E-11 1426 1526
PF08241 Methyltransf_11 Methyltransferase domain 6.8E-10 1427 1530
PF08242 Methyltransf_12 Methyltransferase domain 2.5E-13 1427 1528
PF08659 KR KR domain 6.3E-51 2115 2288
PF00106 adh_short short chain dehydrogenase 2.9E-12 2118 2288
PF00550 PP-binding Phosphopantetheine attachment site 7.9E-06 2411 2465
PF00668 Condensation Condensation domain 9.3E-66 2568 3002
PF00501 AMP-binding AMP-binding enzyme 1.2E-74 3029 3439
PF00550 PP-binding Phosphopantetheine attachment site 9.8E-10 3561 3629
PF01370 Epimerase NAD dependent epimerase/dehydratase family 2.0E-11 3672 3860
PF01073 3Beta_HSD 3-beta hydroxysteroid dehydrogenase/isomerase family 2.3E-08 3673 3837
PF07993 NAD_binding_4 Male sterility protein 4.0E-33 3674 3895
Pro_DTO377G3_2|g8219.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 1.6E-85 34 282
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 1.5E-42 290 407
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 3.6E-13 411 529
PF00698 Acyl_transf_1 Acyl transferase domain 2.2E-65 567 881
PF14765 PS-DH Polyketide synthase dehydratase 8.8E-11 926 1197
PF08659 KR KR domain 6.1E-61 1412 1602
PF00550 PP-binding Phosphopantetheine attachment site 1.9E-12 1704 1767
Pro_DTO377G3_2|g8606.t1 PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain 6.6E-75 2 252
PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain 1.2E-36 261 378
PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension 2.2E-20 382 499
PF00698 Acyl_transf_1 Acyl transferase domain 1.7E-48 530 864
PF14765 PS-DH Polyketide synthase dehydratase 2.0E-46 920 1198
PF08659 KR KR domain 7.5E-58 1978 2156
PF00106 adh_short short chain dehydrogenase 8.8E-13 1981 2139
PF13561 adh_short_C2 Enoyl-(Acyl carrier protein) reductase 2.6E-06 1989 2129
PF00550 PP-binding Phosphopantetheine attachment site 4.9E-06 2267 2323

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