Fungal Genomics

at Utrecht University

General Properties

Protein ID	Ophun1\|4909
Gene name
Location	Contig_466:449..4019
Strand	-
Gene length (bp)	3570
Transcript length (bp)	3291
Coding sequence length (bp)	3291
Protein length (aa)	1097

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF18829	Importin_rep_6	Importin repeat 6	6.0E-35	769	879
PF18808	Importin_rep_4	Importin repeat	8.2E-34	275	367
PF18816	Importin_rep_5	Importin repeat	4.6E-23	1011	1062
PF13513	HEAT_EZ	HEAT-like repeat	1.0E-10	383	437
PF02985	HEAT	HEAT repeat	2.6E-03	411	438
PF12460	MMS19_C	RNAPII transcription regulator C-terminal	1.9E-09	449	566

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|O74476\|IMB3_SCHPO	Importin subunit beta-3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sal3 PE=3 SV=1	6	1095	0.0E+00
sp\|P32337\|IMB3_YEAST	Importin subunit beta-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSE1 PE=1 SV=2	1	1096	0.0E+00
sp\|Q8BKC5\|IPO5_MOUSE	Importin-5 OS=Mus musculus GN=Ipo5 PE=1 SV=3	15	1091	0.0E+00
sp\|O00410\|IPO5_HUMAN	Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4	15	1091	0.0E+00
sp\|Q8BIV3\|RNBP6_MOUSE	Ran-binding protein 6 OS=Mus musculus GN=Ranbp6 PE=1 SV=3	11	1071	7.0E-176

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|O74476\|IMB3_SCHPO	Importin subunit beta-3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sal3 PE=3 SV=1	6	1095	0.0E+00
sp\|P32337\|IMB3_YEAST	Importin subunit beta-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSE1 PE=1 SV=2	1	1096	0.0E+00
sp\|Q8BKC5\|IPO5_MOUSE	Importin-5 OS=Mus musculus GN=Ipo5 PE=1 SV=3	15	1091	0.0E+00
sp\|O00410\|IPO5_HUMAN	Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4	15	1091	0.0E+00
sp\|Q8BIV3\|RNBP6_MOUSE	Ran-binding protein 6 OS=Mus musculus GN=Ranbp6 PE=1 SV=3	11	1071	7.0E-176
sp\|O60518\|RNBP6_HUMAN	Ran-binding protein 6 OS=Homo sapiens GN=RANBP6 PE=1 SV=2	11	1071	1.0E-173
sp\|Q54EW3\|IPO5_DICDI	Probable importin-5 homolog OS=Dictyostelium discoideum GN=DDB_G0291650 PE=3 SV=1	12	1015	1.0E-77
sp\|P40069\|IMB4_YEAST	Importin subunit beta-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP123 PE=1 SV=1	12	632	2.0E-20
sp\|Q8VI75\|IPO4_MOUSE	Importin-4 OS=Mus musculus GN=Ipo4 PE=1 SV=1	10	626	2.0E-16
sp\|Q8H0U4\|TNPO1_ARATH	Transportin-1 OS=Arabidopsis thaliana GN=TRN1 PE=1 SV=1	353	571	6.0E-12
sp\|B8ARW2\|TNPO1_ORYSI	Transportin-1 OS=Oryza sativa subsp. indica GN=OsI_18044 PE=2 SV=1	89	571	4.0E-10
sp\|B9FDR3\|TNPO1_ORYSJ	Transportin-1 OS=Oryza sativa subsp. japonica GN=TRN1 PE=3 SV=2	89	571	5.0E-10
sp\|O14089\|IMB2_SCHPO	Importin subunit beta-2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap104 PE=3 SV=1	353	630	1.0E-06
sp\|Q9FJD4\|IMB1_ARATH	Importin subunit beta-1 OS=Arabidopsis thaliana GN=KPNB1 PE=1 SV=1	11	578	3.0E-06

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GO

GO Term	Description	Terminal node
GO:0005515	protein binding	Yes
GO:0003674	molecular_function	No
GO:0005488	binding	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 19	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophun1\|4909 MSLLSPAVHAELTQLLQALQSADNDIRSQAEEHLQKSWTIARPEVLLMGLVEQIQGAEDNATRSFAAVIFRRISS KTRKIESGENVDMFYSTPRNQAAVIRQKLLETLATEEDRAVRNKISDAVAEVARQYADNNDTWPELLGALFQLSQ APEPEKRENAFRVFTTTPSIIERQHEEAVLQAFQKGFKDDAIRVRLAAMEAFAAFFRTISKKVQTKYFPLISDVL NILPPIKESQESEDLSKALLALIDLAESAPKMFKQLFHNLVQFNISVIQDKELDNICRQNALELMATFADYAPSM CRKDASYTNDMVTQCLSLMTDLGEDDDDAAEWLASDDLDQDESDQNHVAGEQAMDRLANKLGGQTILAPTFNWLP RMMTSMAWRDRHAALMAISAISEGCRDLMIGELSQVLDLVVPALQDPHPRVRWAGCNALGQMSTDFAPKMQTDFY DRVLKAIIPVLSSPEARVKSHAAAALVNFCEEAEKSVLEPYLDDLLSQLFQLLQSDKRYVQEQALSTIATIADAA EAAFSKYYNTLMPLLVSVLQNQSEKEFRLLRSKAMECATLIALAVGRERLGADAMTLVNLLANIQTSITDADDPQ AQYLMHCWGRMCRVLGADFMPFLDSVMPPVLELAMAKADIQLLEDDEQAEQIHGEEGWEFVPLKGKMIGIRTSTM DDKHMAIELLLVYAQTLEGSFAPFVPNIMEKIALPGLAFFFHDPTRYISAKLVPYLLNSYKKAFGCPSNELAGLW HLTVDKLLEVLTAEPSIETLAVMYQCFYESMQVVGRDCLTPAYMNRFIDAVHSTIEDFQDRVAQRAEDKEGATAD DVEDEAEETLMAIEDDQTLLSDMNKAFHSIFRNHGAAFLPAWERLMTTYQGFLASSDATQRQWGLCIVDDVLEYC GPESHRYAGYISQPLIDGCRDASPAIRQAAAYGIGVAAHRGGAPWSQFLGGSVPFLFQVTQVPDPRSEDNVYATE NACAALAKILHYNSGSVANVQGVVAQWIDTLPVINDEEAAPYAYAYLAELIDQRHPAVMNHGSKLFLFVAQALEA ETLQGQTATRVAAATKMLLTSASVDPTPLLHQFSQDSQRTIMGYFS*
Coding	>Ophun1\|4909 ATGTCCTTGCTCTCTCCCGCCGTCCACGCCGAGTTGACCCAGCTGCTCCAGGCCCTGCAGTCCGCCGACAATGAC ATTCGCTCTCAGGCCGAGGAGCATCTCCAGAAGAGCTGGACCATCGCTCGCCCCGAGGTCCTGTTGATGGGTCTC GTCGAGCAGATCCAAGGCGCCGAGGACAATGCCACTCGTTCCTTTGCTGCCGTCATATTTCGCCGCATCTCTTCG AAAACGCGCAAGATCGAGTCGGGCGAAAATGTCGACATGTTCTACTCCACACCAAGAAACCAAGCCGCAGTCATC CGTCAGAAGCTTCTCGAGACCCTCGCGACTGAGGAGGACCGTGCCGTTCGCAACAAAATCAGTGACGCCGTTGCC GAGGTCGCGCGGCAGTACGCCGATAACAATGATACTTGGCCTGAGCTTCTTGGCGCTCTTTTCCAGCTCAGTCAA GCGCCCGAACCCGAGAAACGCGAAAACGCCTTCCGCGTCTTCACCACGACGCCCAGTATCATCGAGAGGCAGCAC GAGGAGGCCGTTCTTCAGGCCTTTCAGAAAGGCTTCAAAGACGATGCCATCAGGGTCCGTCTTGCGGCCATGGAA GCCTTTGCGGCCTTCTTCAGGACCATTAGCAAAAAAGTGCAAACTAAATACTTTCCGCTCATCTCAGACGTTCTC AACATCCTACCTCCAATCAAAGAGTCGCAGGAGTCGGAGGATCTAAGCAAGGCACTCTTGGCCCTCATCGATCTC GCCGAGTCTGCGCCCAAAATGTTCAAACAGTTATTCCACAACCTCGTCCAGTTCAACATTTCCGTCATACAGGAC AAGGAACTCGACAACATCTGCAGACAAAACGCCCTCGAGCTCATGGCCACCTTTGCCGACTACGCTCCCTCGATG TGCCGGAAGGACGCCTCTTACACGAATGATATGGTCACGCAGTGTCTGAGCCTGATGACAGACCTCGGCGAGGAC GACGACGACGCCGCAGAGTGGCTCGCATCTGATGACCTTGATCAAGACGAGAGCGACCAAAACCACGTGGCCGGC GAGCAGGCCATGGACCGTCTCGCCAACAAGCTCGGCGGACAGACCATCCTGGCTCCCACCTTCAACTGGCTTCCC CGAATGATGACGTCCATGGCCTGGAGAGACCGGCACGCGGCTCTGATGGCCATCTCGGCCATTTCGGAAGGATGT CGCGACCTCATGATTGGGGAGCTCAGCCAGGTCCTCGATCTAGTCGTCCCGGCCTTGCAGGATCCGCACCCGCGC GTCCGCTGGGCAGGATGCAACGCGCTGGGGCAGATGAGCACCGACTTTGCCCCCAAGATGCAGACTGATTTCTAC GACAGGGTGCTCAAGGCCATTATCCCGGTCCTCAGCTCCCCCGAGGCTCGAGTCAAGTCTCACGCGGCCGCGGCT CTGGTCAACTTTTGCGAGGAGGCAGAAAAGTCGGTCCTGGAGCCGTATCTCGACGACCTCCTGTCCCAACTGTTC CAGCTGCTCCAGAGCGATAAGCGCTACGTCCAGGAGCAGGCCCTGTCGACCATCGCCACCATTGCCGATGCGGCC GAAGCGGCCTTTTCCAAGTACTACAACACCTTGATGCCCCTCCTCGTCAGTGTTCTTCAGAACCAGAGCGAAAAG GAGTTTCGGCTTCTGCGGTCCAAAGCCATGGAATGCGCCACTCTCATCGCTCTGGCTGTCGGGCGGGAGCGGCTC GGCGCCGACGCCATGACGCTCGTCAATCTCCTCGCCAACATACAGACCAGCATCACGGATGCCGACGATCCGCAA GCGCAGTATCTGATGCACTGCTGGGGGCGCATGTGTCGCGTGCTGGGTGCCGACTTCATGCCGTTCCTGGATAGC GTCATGCCCCCTGTTCTCGAACTGGCCATGGCCAAAGCCGACATACAGCTGCTCGAAGACGACGAACAAGCCGAG CAGATCCACGGCGAGGAGGGCTGGGAGTTTGTCCCGCTCAAGGGCAAGATGATTGGCATCCGGACGAGCACCATG GACGACAAGCACATGGCCATCGAGCTCCTGCTTGTCTACGCTCAGACGCTCGAGGGCTCGTTTGCGCCCTTCGTG CCCAACATCATGGAGAAGATTGCGCTTCCCGGCCTCGCCTTCTTCTTCCACGATCCTACCCGTTACATCTCCGCC AAACTGGTCCCCTACCTCTTGAACTCGTACAAGAAGGCATTCGGCTGCCCCTCCAACGAACTTGCCGGTCTGTGG CACTTGACCGTGGACAAGCTGTTGGAGGTCTTGACGGCCGAGCCGTCGATCGAGACGCTGGCCGTCATGTACCAA TGCTTCTACGAGTCCATGCAAGTGGTCGGCAGGGACTGCCTCACCCCCGCGTACATGAACCGCTTCATCGACGCC GTTCATTCCACAATCGAAGACTTCCAGGACAGAGTCGCTCAGCGTGCCGAGGATAAGGAGGGCGCCACGGCCGAC GATGTCGAGGACGAGGCTGAGGAGACGCTGATGGCCATCGAGGACGACCAGACGCTCCTGTCGGATATGAACAAG GCGTTTCACTCCATCTTCCGGAACCACGGCGCGGCTTTCCTACCTGCTTGGGAGCGGCTCATGACGACGTACCAA GGCTTTCTCGCGTCGTCTGACGCGACTCAGCGACAGTGGGGGCTCTGCATCGTGGACGACGTGCTGGAGTACTGC GGACCGGAGAGCCATCGGTATGCCGGCTACATCTCGCAACCCCTGATCGACGGCTGCAGGGACGCATCGCCGGCC ATCAGGCAGGCGGCAGCTTACGGCATCGGCGTCGCGGCTCATCGAGGCGGCGCTCCGTGGTCTCAGTTCCTCGGA GGATCGGTGCCGTTTCTCTTCCAGGTCACGCAGGTGCCTGACCCCCGGAGCGAAGATAACGTCTACGCTACGGAG AATGCGTGCGCTGCTCTGGCCAAGATCTTGCACTACAACTCGGGCAGCGTCGCAAATGTTCAAGGCGTGGTTGCG CAGTGGATAGACACGCTGCCGGTGATCAACGATGAGGAGGCGGCGCCGTACGCCTATGCCTACCTTGCCGAGCTT ATCGATCAACGCCACCCAGCGGTCATGAACCACGGCAGCAAGTTGTTCCTCTTCGTCGCCCAGGCACTCGAAGCC GAGACTCTCCAGGGACAAACAGCGACGAGAGTGGCAGCGGCCACCAAGATGCTCCTCACAAGTGCCAGCGTGGAC CCGACGCCGCTGCTCCACCAGTTTTCTCAAGACTCGCAGCGGACTATCATGGGGTACTTCAGCTAG
Transcript	>Ophun1\|4909 ATGTCCTTGCTCTCTCCCGCCGTCCACGCCGAGTTGACCCAGCTGCTCCAGGCCCTGCAGTCCGCCGACAATGAC ATTCGCTCTCAGGCCGAGGAGCATCTCCAGAAGAGCTGGACCATCGCTCGCCCCGAGGTCCTGTTGATGGGTCTC GTCGAGCAGATCCAAGGCGCCGAGGACAATGCCACTCGTTCCTTTGCTGCCGTCATATTTCGCCGCATCTCTTCG AAAACGCGCAAGATCGAGTCGGGCGAAAATGTCGACATGTTCTACTCCACACCAAGAAACCAAGCCGCAGTCATC CGTCAGAAGCTTCTCGAGACCCTCGCGACTGAGGAGGACCGTGCCGTTCGCAACAAAATCAGTGACGCCGTTGCC GAGGTCGCGCGGCAGTACGCCGATAACAATGATACTTGGCCTGAGCTTCTTGGCGCTCTTTTCCAGCTCAGTCAA GCGCCCGAACCCGAGAAACGCGAAAACGCCTTCCGCGTCTTCACCACGACGCCCAGTATCATCGAGAGGCAGCAC GAGGAGGCCGTTCTTCAGGCCTTTCAGAAAGGCTTCAAAGACGATGCCATCAGGGTCCGTCTTGCGGCCATGGAA GCCTTTGCGGCCTTCTTCAGGACCATTAGCAAAAAAGTGCAAACTAAATACTTTCCGCTCATCTCAGACGTTCTC AACATCCTACCTCCAATCAAAGAGTCGCAGGAGTCGGAGGATCTAAGCAAGGCACTCTTGGCCCTCATCGATCTC GCCGAGTCTGCGCCCAAAATGTTCAAACAGTTATTCCACAACCTCGTCCAGTTCAACATTTCCGTCATACAGGAC AAGGAACTCGACAACATCTGCAGACAAAACGCCCTCGAGCTCATGGCCACCTTTGCCGACTACGCTCCCTCGATG TGCCGGAAGGACGCCTCTTACACGAATGATATGGTCACGCAGTGTCTGAGCCTGATGACAGACCTCGGCGAGGAC GACGACGACGCCGCAGAGTGGCTCGCATCTGATGACCTTGATCAAGACGAGAGCGACCAAAACCACGTGGCCGGC GAGCAGGCCATGGACCGTCTCGCCAACAAGCTCGGCGGACAGACCATCCTGGCTCCCACCTTCAACTGGCTTCCC CGAATGATGACGTCCATGGCCTGGAGAGACCGGCACGCGGCTCTGATGGCCATCTCGGCCATTTCGGAAGGATGT CGCGACCTCATGATTGGGGAGCTCAGCCAGGTCCTCGATCTAGTCGTCCCGGCCTTGCAGGATCCGCACCCGCGC GTCCGCTGGGCAGGATGCAACGCGCTGGGGCAGATGAGCACCGACTTTGCCCCCAAGATGCAGACTGATTTCTAC GACAGGGTGCTCAAGGCCATTATCCCGGTCCTCAGCTCCCCCGAGGCTCGAGTCAAGTCTCACGCGGCCGCGGCT CTGGTCAACTTTTGCGAGGAGGCAGAAAAGTCGGTCCTGGAGCCGTATCTCGACGACCTCCTGTCCCAACTGTTC CAGCTGCTCCAGAGCGATAAGCGCTACGTCCAGGAGCAGGCCCTGTCGACCATCGCCACCATTGCCGATGCGGCC GAAGCGGCCTTTTCCAAGTACTACAACACCTTGATGCCCCTCCTCGTCAGTGTTCTTCAGAACCAGAGCGAAAAG GAGTTTCGGCTTCTGCGGTCCAAAGCCATGGAATGCGCCACTCTCATCGCTCTGGCTGTCGGGCGGGAGCGGCTC GGCGCCGACGCCATGACGCTCGTCAATCTCCTCGCCAACATACAGACCAGCATCACGGATGCCGACGATCCGCAA GCGCAGTATCTGATGCACTGCTGGGGGCGCATGTGTCGCGTGCTGGGTGCCGACTTCATGCCGTTCCTGGATAGC GTCATGCCCCCTGTTCTCGAACTGGCCATGGCCAAAGCCGACATACAGCTGCTCGAAGACGACGAACAAGCCGAG CAGATCCACGGCGAGGAGGGCTGGGAGTTTGTCCCGCTCAAGGGCAAGATGATTGGCATCCGGACGAGCACCATG GACGACAAGCACATGGCCATCGAGCTCCTGCTTGTCTACGCTCAGACGCTCGAGGGCTCGTTTGCGCCCTTCGTG CCCAACATCATGGAGAAGATTGCGCTTCCCGGCCTCGCCTTCTTCTTCCACGATCCTACCCGTTACATCTCCGCC AAACTGGTCCCCTACCTCTTGAACTCGTACAAGAAGGCATTCGGCTGCCCCTCCAACGAACTTGCCGGTCTGTGG CACTTGACCGTGGACAAGCTGTTGGAGGTCTTGACGGCCGAGCCGTCGATCGAGACGCTGGCCGTCATGTACCAA TGCTTCTACGAGTCCATGCAAGTGGTCGGCAGGGACTGCCTCACCCCCGCGTACATGAACCGCTTCATCGACGCC GTTCATTCCACAATCGAAGACTTCCAGGACAGAGTCGCTCAGCGTGCCGAGGATAAGGAGGGCGCCACGGCCGAC GATGTCGAGGACGAGGCTGAGGAGACGCTGATGGCCATCGAGGACGACCAGACGCTCCTGTCGGATATGAACAAG GCGTTTCACTCCATCTTCCGGAACCACGGCGCGGCTTTCCTACCTGCTTGGGAGCGGCTCATGACGACGTACCAA GGCTTTCTCGCGTCGTCTGACGCGACTCAGCGACAGTGGGGGCTCTGCATCGTGGACGACGTGCTGGAGTACTGC GGACCGGAGAGCCATCGGTATGCCGGCTACATCTCGCAACCCCTGATCGACGGCTGCAGGGACGCATCGCCGGCC ATCAGGCAGGCGGCAGCTTACGGCATCGGCGTCGCGGCTCATCGAGGCGGCGCTCCGTGGTCTCAGTTCCTCGGA GGATCGGTGCCGTTTCTCTTCCAGGTCACGCAGGTGCCTGACCCCCGGAGCGAAGATAACGTCTACGCTACGGAG AATGCGTGCGCTGCTCTGGCCAAGATCTTGCACTACAACTCGGGCAGCGTCGCAAATGTTCAAGGCGTGGTTGCG CAGTGGATAGACACGCTGCCGGTGATCAACGATGAGGAGGCGGCGCCGTACGCCTATGCCTACCTTGCCGAGCTT ATCGATCAACGCCACCCAGCGGTCATGAACCACGGCAGCAAGTTGTTCCTCTTCGTCGCCCAGGCACTCGAAGCC GAGACTCTCCAGGGACAAACAGCGACGAGAGTGGCAGCGGCCACCAAGATGCTCCTCACAAGTGCCAGCGTGGAC CCGACGCCGCTGCTCCACCAGTTTTCTCAAGACTCGCAGCGGACTATCATGGGGTACTTCAGCTAG
Gene	>Ophun1\|4909 ATGTCCTTGCTCTCTCCCGCCGTCCACGCCGAGTTGACCCAGCTGCTCCAGGCCCTGCAGTCCGCCGACAATGAC ATTCGCTCTCAGGCCGAGGAGCATCTCCAGAAGAGCTGGACCATCGCTCGCCCCGAGGTCCTGTTGATGGGTCTC GTCGAGCAGATCCAAGGCGCCGAGGACAATGCCGTGAGTCCAGTCCTGCCTCCCTTCCTATGCGATATCTCTCTG GCTGACGCGTCGACTCTCCTAGACTCGTTCCTTTGCTGCCGTCATATTTCGCCGCATCTCTTCGAAAACGCGCAA GATCGAGTCGGGCGAAAATGTCGACATGTTCTACTCCACACCAAGAAACCAAGCCGCAGTCATCCGTCAGAAGCT TCTCGAGACCCTCGCGACTGAGGAGGACCGTGCCGTTCGCAACAAAATCAGTGACGCCGTTGCCGAGGTCGCGCG GCAGTACGCCGATAACAGTCAGTTCGCCCCGTCATTCTTCTCTCCATCGGGCCTCTCTAATTCTCAGTCTAGATG ATACTTGGCCTGAGCTTCTTGGCGCTCTTTTCCAGCTCAGTCAAGCGCCCGAACCCGAGAAACGCGAAAACGCCT TCCGCGTCTTCACCACGACGCCCAGTATCATCGAGAGGCAGCACGAGGAGGCCGTTCTTCAGGCCTTTCAGAAAG GCTTCAAAGACGATGCCATCAGGGTAGGTTCATCCTCTGGATGCGGTCCGTGGCACGCTAAACAACTTGCCCAGG TCCGTCTTGCGGCCATGGAAGCCTTTGCGGCCTTCTTCAGGACCATTAGCAAAAAAGTGCAAACTAAATACTTTC CGCTCATCTCAGACGTTCTCAACATCCTACCTCCAATCAAAGAGTCGCAGGAGTCGGAGGATCTAAGCAAGGCAC TCTTGGCCCTCATCGATCTCGCCGAGTCTGCGCCCAAAATGTTCAAACAGTTATTCCACAACCTCGTCCAGTTCA ACATTTCCGTCATACAGGACAAGGAACTCGACAACATCTGCAGACAAAACGCCCTCGAGCTCATGGCCACCTTTG CCGACTACGCTCCCTCGATGTGCCGGAAGGACGCCTCTTACACGAATGATATGGTCACGCAGTGTCTGAGCCTGA TGACAGACCTCGGCGAGGACGACGACGACGCCGCAGAGTGGCTCGCATCTGATGACGTGAGTTACGGGTCCAGTT TGTCCGTTGTCCAAGATGACCACTGACACGCATCACCAGCTTGATCAAGACGAGAGCGACCAAAACCACGTGGCC GGCGAGCAGGCCATGGACCGTCTCGCCAACAAGCTCGGCGGACAGACCATCCTGGCTCCCACCTTCAACTGGCTT CCCCGAATGATGACGTCCATGGCCTGGAGAGACCGGCACGCGGCTCTGATGGCCATCTCGGCCATTTCGGAAGGA TGTCGCGACCTCATGATTGGGGAGCTCAGCCAGGTCCTCGATCTAGTCGTCCCGGCCTTGCAGGATCCGCACCCG CGCGTCCGCTGGGCAGGATGCAACGCGCTGGGGCAGATGAGCACCGACTTTGCCCCCAAGATGCAGACTGATTTC TACGACAGGGTGCTCAAGGCCATTATCCCGGTCCTCAGCTCCCCCGAGGCTCGAGTCAAGTCTCACGCGGCCGCG GCTCTGGTCAACTTTTGCGAGGAGGCAGAAAAGTCGGTCCTGGAGCCGTATCTCGACGACCTCCTGTCCCAACTG TTCCAGCTGCTCCAGAGCGATAAGCGCTACGTCCAGGAGCAGGCCCTGTCGACCATCGCCACCATTGCCGATGCG GCCGAAGCGGCCTTTTCCAAGTACTACAACACCTTGATGCCCCTCCTCGTCAGTGTTCTTCAGAACCAGAGCGAA AAGGAGTTTCGGCTTCTGCGGTCCAAAGCCATGGAATGCGCCACTCTCATCGCTCTGGCTGTCGGGCGGGAGCGG CTCGGCGCCGACGCCATGACGCTCGTCAATCTCCTCGCCAACATACAGACCAGCATCACGGATGCCGACGATCCG CAAGCGCAGTATCTGATGCACTGCTGGGGGCGCATGTGTCGCGTGCTGGGTGCCGACTTCATGCCGTTCCTGGAT AGCGTCATGCCCCCTGTTCTCGAACTGGCCATGGCCAAAGCCGACATACAGCTGCTCGAAGACGACGAACAAGCC GAGCAGATCCACGGCGAGGAGGGCTGGGAGTTTGTCCCGCTCAAGGGCAAGATGATTGGCATCCGGACGAGCACC ATGGACGACAAGCACATGGCCATCGAGCTCCTGCTTGTCTACGCTCAGACGCTCGAGGGCTCGTTTGCGCCCTTC GTGCCCAACATCATGGAGAAGATTGCGCTTCCCGGCCTCGCCTTCTTCTTCCACGATCCTACCCGTTACATCTCC GCCAAACTGGTCCCCTACCTCTTGAACTCGTACAAGAAGGCATTCGGCTGCCCCTCCAACGAACTTGCCGGTCTG TGGCACTTGACCGTGGACAAGCTGTTGGAGGTCTTGACGGCCGAGCCGTCGATCGAGACGCTGGCCGTCATGTAC CAATGCTTCTACGAGTCCATGCAAGTGGTCGGCAGGGACTGCCTCACCCCCGCGTACATGAACCGCTTCATCGAC GCCGTTCATTCCACAATCGAAGACTTCCAGGACAGAGTCGCTCAGCGTGCCGAGGATAAGGAGGGCGCCACGGCC GACGATGTCGAGGACGAGGCTGAGGAGACGCTGATGGCCATCGAGGACGACCAGACGCTCCTGTCGGATATGAAC AAGGCGTTTCACTCCATCTTCCGGAACCACGGCGCGGCTTTCCTACCTGCTTGGGAGCGGCTCATGACGACGTAC CAAGGCTTTCTCGCGTCGTCTGACGCGACTCAGCGACAGTGGGGGCTCTGCATCGTGGACGACGTGCTGGAGTAC TGCGGACCGGAGAGCCATCGGTATGCCGGCTACATCTCGCAACCCCTGATCGACGGCTGCAGGGACGCATCGCCG GCCATCAGGCAGGCGGCAGCTTACGGCATCGGCGTCGCGGCTCATCGAGGCGGCGCTCCGTGGTCTCAGTTCCTC GGAGGATCGGTGCCGTTTCTCTTCCAGGTCACGCAGGTGCCTGACCCCCGGAGCGAAGATAACGTCTACGCTACG GAGAATGCGTGCGCTGCTCTGGCCAAGATCTTGCACTACAACTCGGGCAGCGTCGCAAATGTTCAAGGCGTGGTT GCGCAGTGGATAGACACGCTGCCGGTGATCAACGATGAGGAGGCGGCGCCGTACGCCTATGCCTACCTTGCCGAG CTTATCGATCAGTAAGTATTGCGAAACTGTCGGAAGAGAAGCATACTGACTCGTGCCATCAGACGCCACCCAGCG GTCATGAACCACGGCAGCAAGTTGTTCCTCTTCGTCGCCCAGGCACTCGAAGCCGAGACTCTCCAGGGACAAACA GCGACGAGAGTGGCAGCGGCCACCAAGATGCTCCTCACAAGTGCCAGCGTGGACCCGACGCCGCTGCTCCACCAG TTTTCTCAAGACTCGCAGCGGACTATCATGGGGTACTTCAGCTAG

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