Fungal Genomics

at Utrecht University

General Properties

Protein ID	Ophun1\|3731
Gene name
Location	Contig_334:15758..19465
Strand	+
Gene length (bp)	3707
Transcript length (bp)	3597
Coding sequence length (bp)	3597
Protein length (aa)	1199

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00168	C2	C2 domain	4.8E-15	482	582
PF00168	C2	C2 domain	2.1E-08	668	798

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9USG8\|MU190_SCHPO	Meiotically up-regulated gene 190 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug190 PE=1 SV=1	10	1198	0.0E+00
sp\|Q9UT00\|YKH3_SCHPO	Uncharacterized protein PYUK71.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAPYUK71.03c PE=1 SV=1	239	859	6.0E-18
sp\|Q12466\|TCB1_YEAST	Tricalbin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB1 PE=1 SV=1	239	820	7.0E-15
sp\|P48231\|TCB2_YEAST	Tricalbin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB2 PE=1 SV=1	223	625	2.0E-11
sp\|Q9SKR2\|SYT1_ARATH	Synaptotagmin-1 OS=Arabidopsis thaliana GN=SYT1 PE=1 SV=2	188	587	4.0E-10

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9USG8\|MU190_SCHPO	Meiotically up-regulated gene 190 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug190 PE=1 SV=1	10	1198	0.0E+00
sp\|Q9UT00\|YKH3_SCHPO	Uncharacterized protein PYUK71.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAPYUK71.03c PE=1 SV=1	239	859	6.0E-18
sp\|Q12466\|TCB1_YEAST	Tricalbin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB1 PE=1 SV=1	239	820	7.0E-15
sp\|P48231\|TCB2_YEAST	Tricalbin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB2 PE=1 SV=1	223	625	2.0E-11
sp\|Q9SKR2\|SYT1_ARATH	Synaptotagmin-1 OS=Arabidopsis thaliana GN=SYT1 PE=1 SV=2	188	587	4.0E-10
sp\|Q9BSJ8\|ESYT1_HUMAN	Extended synaptotagmin-1 OS=Homo sapiens GN=ESYT1 PE=1 SV=1	188	542	2.0E-09
sp\|O14065\|YC31_SCHPO	Uncharacterized protein C962.01 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC962.01 PE=2 SV=3	239	560	1.0E-08
sp\|Q5RAG2\|ESYT1_PONAB	Extended synaptotagmin-1 OS=Pongo abelii GN=ESYT1 PE=2 SV=2	188	542	2.0E-08
sp\|Q3U7R1\|ESYT1_MOUSE	Extended synaptotagmin-1 OS=Mus musculus GN=Esyt1 PE=1 SV=2	188	542	5.0E-08
sp\|Q7XA06\|SYT3_ARATH	Synaptotagmin-3 OS=Arabidopsis thaliana GN=SYT3 PE=2 SV=1	239	585	7.0E-08
sp\|A0FGR9\|ESYT3_HUMAN	Extended synaptotagmin-3 OS=Homo sapiens GN=ESYT3 PE=1 SV=1	386	576	4.0E-07
sp\|Q8L706\|SYT5_ARATH	Synaptotagmin-5 OS=Arabidopsis thaliana GN=SYT5 PE=2 SV=1	369	799	5.0E-07

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 63	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	187	209	22
2	365	387	22

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophun1\|3731 MDVTEHVLPSGQHYSGRNRVPNIQQFAQQLDLEKRQRDAEIEAELRQNAEAREHHAAEKSKRDHTRTVRDPVTGK DVAISDAHADYKEAVDEPQLSVPNENLGRPTTVRVSSQQSGEDYRRAQDITAPPAPVQEGSTSDVPISSEKTSIL FYKTPSVSYEPMFVALERKATVLCFGIFIAIVFVGKLFGGRLLGLIPLAICVCSGVFLWAQDLVRQGRDVEWSSE QQRGETATANLIPESVEWMNTAIGLVWSLINPEMFASAADTLEDVMVASVPGVIENVRVADISQGSNPIRILSMR ALPDSHVQDIKQEIHQQNEKTMDPNELAAVEQAGSFYNMEVSIAYHAKPSGEDITSKAKNMGMQLIFYLGIKGLF GVPLPVWVELIGLVATARVRLQLTPDPPFLKTLTVTLMGVPKVQAGCTPMIEKGVNILNLPLISNFVNWAIRTAA AMYVAPKSLTLDMSKMLSGDDIKKETQALGVIFIRIHKATGLSKQDHTGSRGGGSDPYITVSWSKFSKPQFCTRV IQDDLNPVFEETCGLLVTSDLIKADEQLSMELWDSDRSSADDVVGKVQLSIQKLIQHPGKMFPQVSHLCGVKADS SMPGHLHWEVGFFGKTQFRKALRTDGRDVTLPKELADKPELQDQRGSIDSKEEDAVVHTPPDPLWPSGILSVVVH QIVGLELANIKGSNGKRKGREYEPARPEAGEVKEEQSRKLPSSYCTVLINDNLVYKTRIKAVSSQPIFNAGTEKF IRDWRSCIATIAVRDSRNRQHDPIIGVVPLQLSDVLRTSSQLTRWYPLDGGIGFGRIRISILFRSVELRLPPPQL GWDIGTFEFTSDSITTTGYAPSQSVKLKLRTGGSSATVKKNMSTREETGMTFDISGGEDGKRMRLPVRHRYRCPI FIEFYSSSSRKPDAYAALWLLELSDGEEEDFEVPIFTCSNGLRLSQNYITQDNYREIPDMKIEEVGRVRFRGRFS PGTDSDHMKFVSDNDSRETIETWEACYAEGVRQEEVKAEVPPVVMELHDKSLTHGRDVLAQADEEDKQRWLAKDG TDWSGAFGKDPRDLMANNADGDGDSEARDDAAGEYDDSSDSDPDLGIEQHPSATGDTTENGRPSAESRGESESSS SSTHDGSGSKNPLTLYKTYTARNRDLHRKHRGLMQWRPMRNVQFAKDEAKFALRKVKNLGGLGGRQPDVETEV*
Coding	>Ophun1\|3731 ATGGACGTCACGGAACATGTCCTGCCCTCGGGCCAGCACTACAGCGGCCGCAACCGCGTCCCCAACATCCAGCAG TTCGCCCAGCAGCTCGACTTGGAGAAGCGCCAGCGAGATGCAGAGATTGAGGCTGAGCTACGTCAGAATGCCGAG GCGCGGGAGCATCATGCTGCGGAGAAGAGCAAGAGGGATCATACGCGCACCGTCCGCGATCCCGTTACGGGGAAG GATGTTGCCATTAGCGATGCTCACGCTGACTACAAGGAGGCTGTCGACGAGCCTCAATTATCCGTCCCCAATGAG AATCTCGGCAGGCCGACGACGGTGAGGGTCTCGTCGCAGCAGTCGGGCGAGGACTACCGTCGTGCTCAAGATATC ACGGCACCGCCCGCTCCGGTCCAGGAAGGATCTACGTCCGACGTCCCCATTAGCAGCGAGAAGACGTCGATTCTG TTCTACAAGACGCCGTCGGTCAGCTACGAGCCCATGTTTGTAGCTCTCGAGCGCAAGGCCACGGTTCTCTGCTTT GGCATTTTCATTGCCATCGTCTTCGTCGGCAAGTTGTTTGGTGGGAGGCTCCTTGGACTCATCCCCTTGGCCATC TGCGTCTGCTCGGGCGTTTTTCTTTGGGCTCAGGATCTCGTCCGTCAGGGCAGGGATGTTGAGTGGTCGAGCGAG CAGCAACGCGGTGAGACGGCTACCGCGAACCTGATTCCCGAGTCTGTCGAGTGGATGAACACGGCCATTGGGCTG GTCTGGAGCCTAATCAATCCCGAGATGTTCGCCTCTGCCGCCGACACACTGGAGGATGTCATGGTTGCCTCGGTC CCGGGTGTCATTGAAAACGTTCGCGTTGCCGACATTTCTCAGGGAAGCAACCCTATCAGGATCCTCAGCATGAGA GCTCTGCCAGACTCTCACGTGCAAGACATCAAGCAGGAGATTCACCAACAAAACGAAAAGACCATGGATCCCAAT GAATTGGCCGCTGTCGAGCAGGCCGGCTCCTTTTACAACATGGAGGTTTCCATCGCCTACCACGCCAAACCGTCG GGCGAGGACATCACGTCCAAAGCCAAGAACATGGGCATGCAGCTCATCTTTTACCTCGGCATCAAGGGTCTCTTC GGTGTGCCGCTGCCCGTCTGGGTCGAGCTGATAGGTCTCGTGGCGACGGCCCGCGTGCGACTGCAGCTGACGCCA GATCCGCCCTTTCTCAAGACTCTCACCGTCACCCTCATGGGCGTCCCCAAGGTGCAGGCCGGCTGTACGCCCATG ATTGAAAAGGGCGTCAACATCCTGAACCTGCCGCTCATATCCAACTTTGTGAACTGGGCCATCCGCACGGCCGCG GCCATGTACGTGGCGCCCAAGAGCTTGACGTTGGATATGAGCAAGATGCTTTCGGGTGACGACATTAAGAAGGAG ACGCAAGCCCTGGGCGTCATCTTCATCCGAATCCACAAGGCGACGGGTCTCAGCAAGCAGGATCACACTGGCAGC CGCGGCGGTGGCTCGGATCCCTACATCACGGTCAGCTGGAGCAAATTCTCCAAGCCTCAGTTCTGCACACGCGTC ATTCAAGACGACCTGAACCCTGTCTTTGAGGAGACTTGCGGTCTATTGGTCACGAGCGACCTCATCAAGGCCGAC GAGCAGCTCTCGATGGAGCTCTGGGACAGCGATCGTTCGTCCGCCGACGACGTCGTGGGCAAGGTCCAGCTCAGC ATCCAGAAGCTCATTCAGCATCCGGGCAAGATGTTCCCTCAGGTCTCTCACCTCTGCGGCGTCAAGGCCGACAGC AGCATGCCCGGTCATCTCCACTGGGAGGTGGGCTTCTTCGGCAAGACGCAGTTCCGCAAGGCGCTGAGGACCGAC GGCCGCGACGTCACCCTGCCCAAGGAGCTGGCTGACAAGCCCGAGCTCCAGGACCAGAGGGGTAGCATCGACAGC AAGGAAGAGGACGCCGTCGTCCACACGCCGCCCGACCCTCTGTGGCCGTCGGGCATCCTCAGCGTCGTCGTCCAC CAGATCGTCGGCCTCGAGCTCGCCAACATCAAGGGCTCCAACGGGAAGCGCAAGGGCAGGGAGTACGAGCCGGCG CGGCCTGAGGCGGGCGAGGTCAAGGAGGAGCAGAGCCGGAAGCTGCCGAGCTCATACTGCACAGTCCTGATCAAT GATAACCTGGTGTACAAGACGCGCATCAAGGCGGTTTCGTCGCAGCCCATCTTCAACGCCGGGACGGAAAAGTTC ATCCGCGACTGGAGATCCTGCATCGCCACCATTGCCGTGCGCGACTCGCGGAACAGGCAGCACGATCCCATCATC GGCGTCGTGCCTCTGCAGCTGTCCGACGTGCTGCGGACGAGCAGCCAGTTGACGCGGTGGTATCCTCTTGACGGC GGCATCGGCTTCGGCCGGATCCGAATCTCCATCCTCTTCCGCTCCGTCGAGCTCCGACTGCCGCCGCCGCAGCTC GGCTGGGATATCGGGACGTTTGAATTCACGTCCGACAGCATCACCACGACGGGATACGCGCCGTCTCAGAGCGTC AAGTTGAAGCTGCGTACGGGCGGATCGTCGGCGACGGTCAAGAAGAATATGTCGACCAGGGAGGAGACGGGGATG ACATTCGACATCAGCGGTGGGGAGGACGGTAAGCGGATGCGACTCCCCGTTCGTCACCGGTATCGATGCCCCATC TTCATCGAGTTTTACTCGTCGAGCAGCCGCAAGCCAGACGCCTACGCTGCCCTGTGGCTGTTGGAGCTCAGCGAC GGGGAAGAGGAGGACTTTGAAGTGCCCATCTTTACCTGCAGCAACGGTCTGCGCCTCTCGCAGAATTACATCACC CAAGACAACTACCGGGAGATTCCCGACATGAAGATTGAAGAGGTCGGTCGCGTCCGGTTCCGCGGCCGTTTCTCA CCCGGCACCGACTCGGACCACATGAAATTTGTCAGCGACAACGATTCCCGAGAGACGATTGAGACGTGGGAGGCG TGCTATGCCGAGGGCGTGCGGCAGGAAGAGGTCAAGGCGGAGGTGCCTCCGGTGGTGATGGAATTGCACGACAAG TCGTTGACGCACGGCCGAGACGTGCTCGCCCAGGCGGACGAAGAAGACAAGCAGCGATGGCTGGCCAAGGACGGC ACGGACTGGAGCGGCGCCTTTGGCAAGGACCCCAGGGACCTGATGGCGAACAACGCGGATGGGGACGGCGACAGC GAAGCGCGGGACGACGCAGCGGGAGAATACGACGACAGCAGCGACAGCGATCCGGACCTCGGCATCGAGCAGCAC CCGAGCGCGACGGGAGATACGACGGAGAATGGCCGACCGTCTGCGGAATCGAGGGGAGAATCGGAGTCTTCGTCT TCGTCTACGCACGACGGCAGCGGGAGCAAGAACCCGTTAACCTTGTACAAGACGTACACGGCACGGAACCGAGAC CTGCATCGCAAGCACCGCGGGTTGATGCAGTGGCGGCCGATGCGCAACGTGCAGTTTGCCAAGGACGAGGCCAAG TTTGCGCTGCGCAAGGTGAAGAATTTGGGGGGGCTGGGAGGGAGGCAGCCGGATGTTGAGACGGAGGTTTAG
Transcript	>Ophun1\|3731 ATGGACGTCACGGAACATGTCCTGCCCTCGGGCCAGCACTACAGCGGCCGCAACCGCGTCCCCAACATCCAGCAG TTCGCCCAGCAGCTCGACTTGGAGAAGCGCCAGCGAGATGCAGAGATTGAGGCTGAGCTACGTCAGAATGCCGAG GCGCGGGAGCATCATGCTGCGGAGAAGAGCAAGAGGGATCATACGCGCACCGTCCGCGATCCCGTTACGGGGAAG GATGTTGCCATTAGCGATGCTCACGCTGACTACAAGGAGGCTGTCGACGAGCCTCAATTATCCGTCCCCAATGAG AATCTCGGCAGGCCGACGACGGTGAGGGTCTCGTCGCAGCAGTCGGGCGAGGACTACCGTCGTGCTCAAGATATC ACGGCACCGCCCGCTCCGGTCCAGGAAGGATCTACGTCCGACGTCCCCATTAGCAGCGAGAAGACGTCGATTCTG TTCTACAAGACGCCGTCGGTCAGCTACGAGCCCATGTTTGTAGCTCTCGAGCGCAAGGCCACGGTTCTCTGCTTT GGCATTTTCATTGCCATCGTCTTCGTCGGCAAGTTGTTTGGTGGGAGGCTCCTTGGACTCATCCCCTTGGCCATC TGCGTCTGCTCGGGCGTTTTTCTTTGGGCTCAGGATCTCGTCCGTCAGGGCAGGGATGTTGAGTGGTCGAGCGAG CAGCAACGCGGTGAGACGGCTACCGCGAACCTGATTCCCGAGTCTGTCGAGTGGATGAACACGGCCATTGGGCTG GTCTGGAGCCTAATCAATCCCGAGATGTTCGCCTCTGCCGCCGACACACTGGAGGATGTCATGGTTGCCTCGGTC CCGGGTGTCATTGAAAACGTTCGCGTTGCCGACATTTCTCAGGGAAGCAACCCTATCAGGATCCTCAGCATGAGA GCTCTGCCAGACTCTCACGTGCAAGACATCAAGCAGGAGATTCACCAACAAAACGAAAAGACCATGGATCCCAAT GAATTGGCCGCTGTCGAGCAGGCCGGCTCCTTTTACAACATGGAGGTTTCCATCGCCTACCACGCCAAACCGTCG GGCGAGGACATCACGTCCAAAGCCAAGAACATGGGCATGCAGCTCATCTTTTACCTCGGCATCAAGGGTCTCTTC GGTGTGCCGCTGCCCGTCTGGGTCGAGCTGATAGGTCTCGTGGCGACGGCCCGCGTGCGACTGCAGCTGACGCCA GATCCGCCCTTTCTCAAGACTCTCACCGTCACCCTCATGGGCGTCCCCAAGGTGCAGGCCGGCTGTACGCCCATG ATTGAAAAGGGCGTCAACATCCTGAACCTGCCGCTCATATCCAACTTTGTGAACTGGGCCATCCGCACGGCCGCG GCCATGTACGTGGCGCCCAAGAGCTTGACGTTGGATATGAGCAAGATGCTTTCGGGTGACGACATTAAGAAGGAG ACGCAAGCCCTGGGCGTCATCTTCATCCGAATCCACAAGGCGACGGGTCTCAGCAAGCAGGATCACACTGGCAGC CGCGGCGGTGGCTCGGATCCCTACATCACGGTCAGCTGGAGCAAATTCTCCAAGCCTCAGTTCTGCACACGCGTC ATTCAAGACGACCTGAACCCTGTCTTTGAGGAGACTTGCGGTCTATTGGTCACGAGCGACCTCATCAAGGCCGAC GAGCAGCTCTCGATGGAGCTCTGGGACAGCGATCGTTCGTCCGCCGACGACGTCGTGGGCAAGGTCCAGCTCAGC ATCCAGAAGCTCATTCAGCATCCGGGCAAGATGTTCCCTCAGGTCTCTCACCTCTGCGGCGTCAAGGCCGACAGC AGCATGCCCGGTCATCTCCACTGGGAGGTGGGCTTCTTCGGCAAGACGCAGTTCCGCAAGGCGCTGAGGACCGAC GGCCGCGACGTCACCCTGCCCAAGGAGCTGGCTGACAAGCCCGAGCTCCAGGACCAGAGGGGTAGCATCGACAGC AAGGAAGAGGACGCCGTCGTCCACACGCCGCCCGACCCTCTGTGGCCGTCGGGCATCCTCAGCGTCGTCGTCCAC CAGATCGTCGGCCTCGAGCTCGCCAACATCAAGGGCTCCAACGGGAAGCGCAAGGGCAGGGAGTACGAGCCGGCG CGGCCTGAGGCGGGCGAGGTCAAGGAGGAGCAGAGCCGGAAGCTGCCGAGCTCATACTGCACAGTCCTGATCAAT GATAACCTGGTGTACAAGACGCGCATCAAGGCGGTTTCGTCGCAGCCCATCTTCAACGCCGGGACGGAAAAGTTC ATCCGCGACTGGAGATCCTGCATCGCCACCATTGCCGTGCGCGACTCGCGGAACAGGCAGCACGATCCCATCATC GGCGTCGTGCCTCTGCAGCTGTCCGACGTGCTGCGGACGAGCAGCCAGTTGACGCGGTGGTATCCTCTTGACGGC GGCATCGGCTTCGGCCGGATCCGAATCTCCATCCTCTTCCGCTCCGTCGAGCTCCGACTGCCGCCGCCGCAGCTC GGCTGGGATATCGGGACGTTTGAATTCACGTCCGACAGCATCACCACGACGGGATACGCGCCGTCTCAGAGCGTC AAGTTGAAGCTGCGTACGGGCGGATCGTCGGCGACGGTCAAGAAGAATATGTCGACCAGGGAGGAGACGGGGATG ACATTCGACATCAGCGGTGGGGAGGACGGTAAGCGGATGCGACTCCCCGTTCGTCACCGGTATCGATGCCCCATC TTCATCGAGTTTTACTCGTCGAGCAGCCGCAAGCCAGACGCCTACGCTGCCCTGTGGCTGTTGGAGCTCAGCGAC GGGGAAGAGGAGGACTTTGAAGTGCCCATCTTTACCTGCAGCAACGGTCTGCGCCTCTCGCAGAATTACATCACC CAAGACAACTACCGGGAGATTCCCGACATGAAGATTGAAGAGGTCGGTCGCGTCCGGTTCCGCGGCCGTTTCTCA CCCGGCACCGACTCGGACCACATGAAATTTGTCAGCGACAACGATTCCCGAGAGACGATTGAGACGTGGGAGGCG TGCTATGCCGAGGGCGTGCGGCAGGAAGAGGTCAAGGCGGAGGTGCCTCCGGTGGTGATGGAATTGCACGACAAG TCGTTGACGCACGGCCGAGACGTGCTCGCCCAGGCGGACGAAGAAGACAAGCAGCGATGGCTGGCCAAGGACGGC ACGGACTGGAGCGGCGCCTTTGGCAAGGACCCCAGGGACCTGATGGCGAACAACGCGGATGGGGACGGCGACAGC GAAGCGCGGGACGACGCAGCGGGAGAATACGACGACAGCAGCGACAGCGATCCGGACCTCGGCATCGAGCAGCAC CCGAGCGCGACGGGAGATACGACGGAGAATGGCCGACCGTCTGCGGAATCGAGGGGAGAATCGGAGTCTTCGTCT TCGTCTACGCACGACGGCAGCGGGAGCAAGAACCCGTTAACCTTGTACAAGACGTACACGGCACGGAACCGAGAC CTGCATCGCAAGCACCGCGGGTTGATGCAGTGGCGGCCGATGCGCAACGTGCAGTTTGCCAAGGACGAGGCCAAG TTTGCGCTGCGCAAGGTGAAGAATTTGGGGGGGCTGGGAGGGAGGCAGCCGGATGTTGAGACGGAGGTTTAG
Gene	>Ophun1\|3731 ATGGACGTCACGGAACATGTCCTGCCCTCGGGCCAGCACTACAGCGGCCGCAACCGCGTCCCCAACATCCAGCAG TTCGCCCAGCAGCTCGACTTGGAGAAGCGCCAGCGAGATGCAGAGATTGAGGCTGAGCTACGTCAGAATGCCGAG GCGCGGGAGCATCATGCTGCGGAGAAGAGCAAGAGGGATCATACGCGCACCGTCCGCGATCCCGTTACGGGGAAG GATGTTGCCATTAGCGATGCTCACGCTGACTACAAGGAGGCTGTCGACGAGCCTCAAGTGCGTGCTCCTTTGCCT CTCTCATCGTCTTGTTTGAAGCTGACGACTGTCTTTAGTTATCCGTCCCCAATGAGAATCTCGGCAGGCCGACGA CGGTGAGGGTCTCGTCGCAGCAGTCGGGCGAGGACTACCGTCGTGCTCAAGATATCACGGCACCGCCCGCTCCGG TCCAGGAAGGATCTACGTCCGACGTCCCCATTAGCAGCGAGAAGACGTCGATTCTGTTCTACAAGACGCCGTCGG TCAGCTACGAGCCCATGTTTGTAGCTCTCGAGCGCAAGGCCACGGTTCTCTGCTTTGGCATTTTCATTGCCATCG TCTTCGTCGGCAAGTTGTTTGGTGGGAGGCTCCTTGGACTCATCCCCTTGGCCATCTGCGTCTGCTCGGGCGTTT TTCTTTGGGCTCAGGATCTCGTCCGTCAGGGCAGGGATGTTGAGTGGTCGAGCGAGCAGCAACGCGGTGAGACGG CTACCGCGAACCTGATTCCCGAGTCTGTCGAGTGGATGAACACGGCCATTGGGCTGGTCTGGAGCCTAATCAATC CCGAGATGTTCGCCTCTGCCGCCGACACGTGAGTCTTGCTCTTTGTTCGTGGCTGAGGATGAGAGCGCTGACTGG CTAGCAGACTGGAGGATGTCATGGTTGCCTCGGTCCCGGGTGTCATTGAAAACGTTCGCGTTGCCGACATTTCTC AGGGAAGCAACCCTATCAGGATCCTCAGCATGAGAGCTCTGCCAGACTCTCACGTGCAAGACATCAAGCAGGAGA TTCACCAACAAAACGAAAAGACCATGGATCCCAATGAATTGGCCGCTGTCGAGCAGGCCGGCTCCTTTTACAACA TGGAGGTTTCCATCGCCTACCACGCCAAACCGTCGGGCGAGGACATCACGTCCAAAGCCAAGAACATGGGCATGC AGCTCATCTTTTACCTCGGCATCAAGGGTCTCTTCGGTGTGCCGCTGCCCGTCTGGGTCGAGCTGATAGGTCTCG TGGCGACGGCCCGCGTGCGACTGCAGCTGACGCCAGATCCGCCCTTTCTCAAGACTCTCACCGTCACCCTCATGG GCGTCCCCAAGGTGCAGGCCGGCTGTACGCCCATGATTGAAAAGGGCGTCAACATCCTGAACCTGCCGCTCATAT CCAACTTTGTGAACTGGGCCATCCGCACGGCCGCGGCCATGTACGTGGCGCCCAAGAGCTTGACGTTGGATATGA GCAAGATGCTTTCGGGTGACGACATTAAGAAGGAGACGCAAGCCCTGGGCGTCATCTTCATCCGAATCCACAAGG CGACGGGTCTCAGCAAGCAGGATCACACTGGCAGCCGCGGCGGTGGCTCGGATCCCTACATCACGGTCAGCTGGA GCAAATTCTCCAAGCCTCAGTTCTGCACACGCGTCATTCAAGACGACCTGAACCCTGTCTTTGAGGAGACTTGCG GTCTATTGGTCACGAGCGACCTCATCAAGGCCGACGAGCAGCTCTCGATGGAGCTCTGGGACAGCGATCGTTCGT CCGCCGACGACGTCGTGGGCAAGGTCCAGCTCAGCATCCAGAAGCTCATTCAGCATCCGGGCAAGATGTTCCCTC AGGTCTCTCACCTCTGCGGCGTCAAGGCCGACAGCAGCATGCCCGGTCATCTCCACTGGGAGGTGGGCTTCTTCG GCAAGACGCAGTTCCGCAAGGCGCTGAGGACCGACGGCCGCGACGTCACCCTGCCCAAGGAGCTGGCTGACAAGC CCGAGCTCCAGGACCAGAGGGGTAGCATCGACAGCAAGGAAGAGGACGCCGTCGTCCACACGCCGCCCGACCCTC TGTGGCCGTCGGGCATCCTCAGCGTCGTCGTCCACCAGATCGTCGGCCTCGAGCTCGCCAACATCAAGGGCTCCA ACGGGAAGCGCAAGGGCAGGGAGTACGAGCCGGCGCGGCCTGAGGCGGGCGAGGTCAAGGAGGAGCAGAGCCGGA AGCTGCCGAGCTCATACTGCACAGTCCTGATCAATGATAACCTGGTGTACAAGACGCGCATCAAGGCGGTTTCGT CGCAGCCCATCTTCAACGCCGGGACGGAAAAGTTCATCCGCGACTGGAGATCCTGCATCGCCACCATTGCCGTGC GCGACTCGCGGAACAGGCAGCACGATCCCATCATCGGCGTCGTGCCTCTGCAGCTGTCCGACGTGCTGCGGACGA GCAGCCAGTTGACGCGGTGGTATCCTCTTGACGGCGGCATCGGCTTCGGCCGGATCCGAATCTCCATCCTCTTCC GCTCCGTCGAGCTCCGACTGCCGCCGCCGCAGCTCGGCTGGGATATCGGGACGTTTGAATTCACGTCCGACAGCA TCACCACGACGGGATACGCGCCGTCTCAGAGCGTCAAGTTGAAGCTGCGTACGGGCGGATCGTCGGCGACGGTCA AGAAGAATATGTCGACCAGGGAGGAGACGGGGATGACATTCGACATCAGCGGTGGGGAGGACGGTAAGCGGATGC GACTCCCCGTTCGTCACCGGTATCGATGCCCCATCTTCATCGAGTTTTACTCGTCGAGCAGCCGCAAGCCAGACG CCTACGCTGCCCTGTGGCTGTTGGAGCTCAGCGACGGGGAAGAGGAGGACTTTGAAGTGCCCATCTTTACCTGCA GCAACGGTCTGCGCCTCTCGCAGAATTACATCACCCAAGACAACTACCGGGAGATTCCCGACATGAAGATTGAAG AGGTCGGTCGCGTCCGGTTCCGCGGCCGTTTCTCACCCGGCACCGACTCGGACCACATGAAATTTGTCAGCGACA ACGATTCCCGAGAGACGATTGAGACGTGGGAGGCGTGCTATGCCGAGGGCGTGCGGCAGGAAGAGGTCAAGGCGG AGGTGCCTCCGGTGGTGATGGAATTGCACGACAAGTCGTTGACGCACGGCCGAGACGTGCTCGCCCAGGCGGACG AAGAAGACAAGCAGCGATGGCTGGCCAAGGACGGCACGGACTGGAGCGGCGCCTTTGGCAAGGACCCCAGGGACC TGATGGCGAACAACGCGGATGGGGACGGCGACAGCGAAGCGCGGGACGACGCAGCGGGAGAATACGACGACAGCA GCGACAGCGATCCGGACCTCGGCATCGAGCAGCACCCGAGCGCGACGGGAGATACGACGGAGAATGGCCGACCGT CTGCGGAATCGAGGGGAGAATCGGAGTCTTCGTCTTCGTCTACGCACGACGGCAGCGGGAGCAAGAACCCGTTAA CCTTGTACAAGACGTACACGGCACGGAACCGAGACCTGCATCGCAAGCACCGCGGGTTGATGCAGTGGCGGCCGA TGCGCAACGTGCAGTTTGCCAAGGACGAGGCCAAGTTTGCGCTGCGCAAGGTGAAGAATTTGGGGGGGCTGGGAG GGAGGCAGCCGGATGTTGAGACGGAGGTTTAG

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