Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophun1|3106
Gene name
Location	Contig_277:58..4955
Strand	-
Gene length (bp)	4897
Transcript length (bp)	3468
Coding sequence length (bp)	3468
Protein length (aa)	1156

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00790	VHS	VHS domain	8.3E-21	757	891
PF00069	Pkinase	Protein kinase domain	6.8E-19	380	661

Swissprot hits

GO

GO Term	Description	Terminal node
GO:0035091	phosphatidylinositol binding	Yes
GO:0005524	ATP binding	Yes
GO:0004672	protein kinase activity	Yes
GO:0006468	protein phosphorylation	Yes
GO:0043130	ubiquitin binding	Yes
GO:0019538	protein metabolic process	No
GO:0044237	cellular metabolic process	No
GO:0030554	adenyl nucleotide binding	No
GO:0043170	macromolecule metabolic process	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0016740	transferase activity	No
GO:0016301	kinase activity	No
GO:0006796	phosphate-containing compound metabolic process	No
GO:0097159	organic cyclic compound binding	No
GO:0008152	metabolic process	No
GO:0016772	transferase activity, transferring phosphorus-containing groups	No
GO:0005543	phospholipid binding	No
GO:0097367	carbohydrate derivative binding	No
GO:0003824	catalytic activity	No
GO:0009987	cellular process	No
GO:0036094	small molecule binding	No
GO:1901363	heterocyclic compound binding	No
GO:0032555	purine ribonucleotide binding	No
GO:0017076	purine nucleotide binding	No
GO:0008289	lipid binding	No
GO:0006807	nitrogen compound metabolic process	No
GO:0000166	nucleotide binding	No
GO:0071704	organic substance metabolic process	No
GO:0044238	primary metabolic process	No
GO:0005488	binding	No
GO:0008150	biological_process	No
GO:0043168	anion binding	No
GO:1901265	nucleoside phosphate binding	No
GO:1901564	organonitrogen compound metabolic process	No
GO:0032182	ubiquitin-like protein binding	No
GO:0016773	phosphotransferase activity, alcohol group as acceptor	No
GO:0003674	molecular_function	No
GO:0032553	ribonucleotide binding	No
GO:0005515	protein binding	No
GO:0006793	phosphorus metabolic process	No
GO:0016310	phosphorylation	No
GO:0036211	protein modification process	No
GO:0043167	ion binding	No
GO:0043412	macromolecule modification	No
GO:0035639	purine ribonucleoside triphosphate binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophun1|3106 MPHPGQETAHDANDIHLERLLKLTDHVADVFTQILSHQRDLPYRVLDSLDKQAARFKCWRIVAGLSTSSHHGQAL AVARLDDAPAMRGALIAALEYLCLQLGAGERQKFGRWPAEDTETCSSNSRDRVLSMDAINRVESTITTLHQLSIS NRRTALLTSTDLLVQLYQSDNEDPVAELSIRLLSKRVWSAFSASYFIPDDALHTVIDVASTERVLAAASPERHST KTAACARTVCQDADSAGLRRVFAVLVLLRSISALDAFIHLSLTDGRLPLLPNDAVWIELIEAVDGDTVHRFAELQ WLVLAPRLIRHHDTETYCLDRSAIVPCLEAQVIPKFGGDPDSTQPGHEHRQPIILQCSPVWKVKIHAGHIAASHK RDTPYFAFKQQQGLSEREALGEIANLRELRYLGRPQEHIIELLDSFFYKDDFYLVFDWAEDNLMQYWQRNGEPKL TKGLLRWASSQISGLTQGLAAIHDELMGFHGDITSHNVLRFTGTDTSSPYGTLKLSDFGLAQFPGRCHQSGSSSE RFYDLHCDPTYQSPECQPPESPNDMPMNVTQKSDIWPLGCVYLNFVTWLVCGWTGLEQFSHQRLDEHESDMQVDS FFKIEDETRPRPVLKTSVSRRMDQFKSIESQPMFTHDLVDVIRDNMLQVNPRKRLSSRALCDWLLELHDKCQNTQ RGPEDDEATLVSSPRVTQAIKVRYVRRSSLKLFLNELFPECPVKMSHIDDMWIVTLPRKLTEPSCFCNDIARPPS MFSQKKPYSAITVTIENLTSESYSVDSFSGIPDLVEVIKLQATGPTEAARAIRKKLKYGNVHRQLRALVILDGLI QNAGSNFQRTFADEPLLERLRVCGTSGLSDAAVRNKATELFREWSQYANTPGLERVARLYRELPKRKVTVTQDKS KVIRETENPFGDDDEPEPDRGSRAGPEPTSSARSSQHADQDKKKKKKDIKPRFGSSRRSFSLEAEKESIKSVIAE ASIESTNLMNSLQSINRERQRISENRGAVQHFDACKQLRRRILRYIHLVDSEQWLGSLLHANDELVHALMSFEQL DRSIDADSDSDDELAEQAHLYRMNTGTHRSTANPATSSARTLELAGLTLNPSPKPAPPPVPRAPQPAHGPRVDQL KMPKQEEDDDPFSDNNVVGTPPLEREEPRW*
Coding	>Ophun1|3106 ATGCCTCATCCCGGACAAGAAACAGCTCACGATGCCAACGACATCCACCTCGAGCGCCTCCTAAAGCTGACCGAC CACGTGGCCGACGTGTTTACCCAGATTCTGAGCCATCAGAGAGACCTGCCATACCGTGTCTTGGATTCCCTCGAC AAGCAAGCTGCCAGGTTCAAGTGCTGGAGGATCGTCGCCGGCCTCTCGACATCTTCCCACCATGGCCAGGCTCTC GCCGTGGCTCGCCTTGATGATGCTCCCGCCATGAGGGGCGCCCTAATTGCTGCTCTAGAGTACCTGTGTCTTCAG TTGGGTGCCGGTGAGCGTCAGAAGTTCGGACGCTGGCCCGCAGAAGACACCGAGACATGCTCTAGCAACAGCAGA GATCGAGTCTTGTCCATGGACGCCATAAACCGAGTCGAGTCGACCATTACAACGCTCCATCAACTTTCTATTTCC AACAGGCGGACTGCTCTTCTGACCTCCACCGACCTCCTCGTTCAGTTATATCAGTCGGACAATGAAGACCCCGTG GCTGAGCTGTCCATCAGGTTGCTGTCCAAGCGAGTCTGGTCGGCCTTTAGTGCCAGCTACTTCATCCCAGACGAT GCCCTGCACACCGTCATAGACGTGGCCAGCACGGAAAGGGTCCTAGCTGCGGCGTCTCCGGAGCGCCATAGCACC AAGACAGCAGCTTGTGCGAGGACTGTTTGTCAAGATGCCGACTCCGCCGGACTGCGCCGAGTCTTTGCGGTTCTG GTACTGCTACGCAGCATCAGCGCTCTCGACGCCTTTATCCACCTCTCGCTGACTGACGGTCGTCTACCACTGCTA CCAAACGATGCCGTATGGATAGAGTTGATAGAAGCTGTTGATGGTGATACGGTTCATCGATTCGCCGAACTCCAA TGGCTGGTTCTTGCACCACGACTCATCAGGCATCATGACACCGAAACCTACTGCTTGGATCGCTCAGCTATAGTT CCTTGCCTGGAGGCTCAGGTTATACCGAAGTTTGGTGGGGATCCAGACTCAACGCAGCCAGGCCACGAACATAGA CAGCCCATCATCCTTCAGTGCAGTCCCGTGTGGAAGGTCAAGATTCATGCTGGCCACATAGCAGCGTCCCATAAG AGGGATACCCCGTACTTTGCCTTCAAGCAACAACAAGGCTTGTCGGAACGGGAGGCCTTGGGGGAGATTGCCAAC CTGAGAGAACTGCGATATCTCGGTCGTCCGCAAGAGCACATCATCGAGCTGCTAGACTCCTTCTTCTACAAGGAT GACTTCTATCTAGTGTTTGACTGGGCAGAAGACAACCTGATGCAGTATTGGCAGCGAAATGGTGAGCCCAAGTTG ACCAAGGGGTTGCTGAGATGGGCCAGCTCGCAGATATCTGGACTTACTCAGGGCCTTGCGGCGATTCACGACGAG CTGATGGGCTTCCACGGAGACATCACGTCACACAACGTCCTCAGATTCACCGGAACAGACACCTCAAGTCCCTAC GGCACCCTCAAACTGTCAGACTTTGGACTGGCACAGTTCCCTGGACGTTGCCACCAATCGGGCTCCTCCAGCGAG CGATTCTACGATCTGCATTGCGACCCGACCTACCAGTCTCCGGAGTGTCAACCGCCGGAGAGCCCGAACGATATG CCCATGAACGTCACTCAGAAGTCCGACATCTGGCCCCTTGGCTGCGTCTACCTCAACTTCGTGACGTGGCTGGTC TGTGGCTGGACTGGGTTGGAGCAGTTTTCCCATCAACGACTGGACGAGCATGAATCGGACATGCAAGTCGACTCT TTCTTCAAAATCGAGGATGAAACACGCCCGCGCCCCGTTCTGAAAACCTCGGTCAGCCGGAGAATGGATCAGTTC AAGAGTATCGAGTCCCAGCCAATGTTTACCCATGATCTGGTCGACGTCATACGGGACAATATGCTCCAGGTGAAC CCACGGAAACGCCTCTCTTCTCGAGCCTTATGTGATTGGCTTCTGGAGTTGCATGACAAGTGCCAGAATACGCAG CGAGGCCCGGAAGATGATGAAGCGACGCTGGTCTCCTCCCCGCGGGTCACGCAGGCTATTAAAGTGAGATATGTC AGGCGAAGTTCGCTGAAATTGTTTCTCAACGAGTTGTTTCCCGAATGCCCCGTCAAGATGAGCCACATTGACGAC ATGTGGATAGTTACCCTGCCGAGGAAACTCACCGAGCCCTCGTGCTTCTGCAACGACATCGCACGGCCGCCCAGC ATGTTCTCTCAGAAGAAACCGTACTCGGCCATTACCGTCACCATCGAGAATCTCACCAGCGAATCCTACAGCGTC GACAGCTTCAGCGGCATCCCTGACCTGGTCGAGGTCATCAAGCTCCAGGCCACGGGCCCTACAGAGGCGGCGCGG GCCATCCGCAAGAAGCTCAAGTACGGCAATGTCCACCGCCAGCTCCGCGCCCTCGTCATTCTCGACGGGCTCATC CAGAATGCCGGATCCAACTTCCAGCGCACCTTTGCCGACGAGCCCCTGCTCGAGCGGCTCAGGGTGTGCGGCACT TCGGGCCTTTCCGACGCAGCCGTCAGGAACAAGGCCACGGAGCTTTTCCGGGAGTGGTCGCAATACGCCAACACT CCCGGGCTGGAGCGCGTCGCCCGGCTTTACAGGGAACTTCCCAAGAGAAAGGTGACGGTCACGCAAGATAAATCA AAGGTCATACGCGAGACCGAGAACCCGTTTGGAGACGACGATGAACCCGAGCCAGACCGTGGTTCACGAGCTGGG CCGGAACCGACCTCGTCAGCCAGGTCCAGCCAACACGCCGACCAGGACAAGAAGAAGAAGAAAAAGGACATCAAG CCCAGGTTTGGGAGCAGCCGCAGATCGTTTAGCCTCGAGGCGGAAAAGGAGTCGATCAAGTCCGTAATCGCCGAA GCGTCCATCGAGTCGACCAACCTGATGAACTCGCTCCAGAGCATCAACCGCGAGCGCCAGCGCATTTCGGAGAAC CGGGGGGCTGTGCAGCACTTTGACGCGTGCAAGCAGCTCCGGCGAAGGATCCTCCGCTACATCCACCTGGTTGAC AGCGAGCAATGGCTCGGCAGCCTGCTTCACGCCAACGACGAGCTCGTGCATGCCCTCATGTCGTTTGAGCAGCTG GACCGGTCCATCGATGCCGATAGCGACTCGGACGACGAGCTGGCCGAGCAAGCTCACCTCTATCGAATGAACACG GGCACGCACAGGAGCACAGCCAACCCGGCGACATCGAGTGCCCGCACCCTGGAACTGGCCGGTCTCACCCTCAAC CCTTCTCCCAAGCCGGCCCCGCCTCCAGTTCCTCGGGCGCCACAGCCGGCTCATGGGCCGCGCGTTGATCAGCTC AAGATGCCCAAGCAGGAAGAGGACGACGACCCTTTCAGCGACAACAACGTGGTAGGGACGCCACCGCTCGAGCGA GAGGAGCCCCGCTGGTAG
Transcript	>Ophun1|3106 ATGCCTCATCCCGGACAAGAAACAGCTCACGATGCCAACGACATCCACCTCGAGCGCCTCCTAAAGCTGACCGAC CACGTGGCCGACGTGTTTACCCAGATTCTGAGCCATCAGAGAGACCTGCCATACCGTGTCTTGGATTCCCTCGAC AAGCAAGCTGCCAGGTTCAAGTGCTGGAGGATCGTCGCCGGCCTCTCGACATCTTCCCACCATGGCCAGGCTCTC GCCGTGGCTCGCCTTGATGATGCTCCCGCCATGAGGGGCGCCCTAATTGCTGCTCTAGAGTACCTGTGTCTTCAG TTGGGTGCCGGTGAGCGTCAGAAGTTCGGACGCTGGCCCGCAGAAGACACCGAGACATGCTCTAGCAACAGCAGA GATCGAGTCTTGTCCATGGACGCCATAAACCGAGTCGAGTCGACCATTACAACGCTCCATCAACTTTCTATTTCC AACAGGCGGACTGCTCTTCTGACCTCCACCGACCTCCTCGTTCAGTTATATCAGTCGGACAATGAAGACCCCGTG GCTGAGCTGTCCATCAGGTTGCTGTCCAAGCGAGTCTGGTCGGCCTTTAGTGCCAGCTACTTCATCCCAGACGAT GCCCTGCACACCGTCATAGACGTGGCCAGCACGGAAAGGGTCCTAGCTGCGGCGTCTCCGGAGCGCCATAGCACC AAGACAGCAGCTTGTGCGAGGACTGTTTGTCAAGATGCCGACTCCGCCGGACTGCGCCGAGTCTTTGCGGTTCTG GTACTGCTACGCAGCATCAGCGCTCTCGACGCCTTTATCCACCTCTCGCTGACTGACGGTCGTCTACCACTGCTA CCAAACGATGCCGTATGGATAGAGTTGATAGAAGCTGTTGATGGTGATACGGTTCATCGATTCGCCGAACTCCAA TGGCTGGTTCTTGCACCACGACTCATCAGGCATCATGACACCGAAACCTACTGCTTGGATCGCTCAGCTATAGTT CCTTGCCTGGAGGCTCAGGTTATACCGAAGTTTGGTGGGGATCCAGACTCAACGCAGCCAGGCCACGAACATAGA CAGCCCATCATCCTTCAGTGCAGTCCCGTGTGGAAGGTCAAGATTCATGCTGGCCACATAGCAGCGTCCCATAAG AGGGATACCCCGTACTTTGCCTTCAAGCAACAACAAGGCTTGTCGGAACGGGAGGCCTTGGGGGAGATTGCCAAC CTGAGAGAACTGCGATATCTCGGTCGTCCGCAAGAGCACATCATCGAGCTGCTAGACTCCTTCTTCTACAAGGAT GACTTCTATCTAGTGTTTGACTGGGCAGAAGACAACCTGATGCAGTATTGGCAGCGAAATGGTGAGCCCAAGTTG ACCAAGGGGTTGCTGAGATGGGCCAGCTCGCAGATATCTGGACTTACTCAGGGCCTTGCGGCGATTCACGACGAG CTGATGGGCTTCCACGGAGACATCACGTCACACAACGTCCTCAGATTCACCGGAACAGACACCTCAAGTCCCTAC GGCACCCTCAAACTGTCAGACTTTGGACTGGCACAGTTCCCTGGACGTTGCCACCAATCGGGCTCCTCCAGCGAG CGATTCTACGATCTGCATTGCGACCCGACCTACCAGTCTCCGGAGTGTCAACCGCCGGAGAGCCCGAACGATATG CCCATGAACGTCACTCAGAAGTCCGACATCTGGCCCCTTGGCTGCGTCTACCTCAACTTCGTGACGTGGCTGGTC TGTGGCTGGACTGGGTTGGAGCAGTTTTCCCATCAACGACTGGACGAGCATGAATCGGACATGCAAGTCGACTCT TTCTTCAAAATCGAGGATGAAACACGCCCGCGCCCCGTTCTGAAAACCTCGGTCAGCCGGAGAATGGATCAGTTC AAGAGTATCGAGTCCCAGCCAATGTTTACCCATGATCTGGTCGACGTCATACGGGACAATATGCTCCAGGTGAAC CCACGGAAACGCCTCTCTTCTCGAGCCTTATGTGATTGGCTTCTGGAGTTGCATGACAAGTGCCAGAATACGCAG CGAGGCCCGGAAGATGATGAAGCGACGCTGGTCTCCTCCCCGCGGGTCACGCAGGCTATTAAAGTGAGATATGTC AGGCGAAGTTCGCTGAAATTGTTTCTCAACGAGTTGTTTCCCGAATGCCCCGTCAAGATGAGCCACATTGACGAC ATGTGGATAGTTACCCTGCCGAGGAAACTCACCGAGCCCTCGTGCTTCTGCAACGACATCGCACGGCCGCCCAGC ATGTTCTCTCAGAAGAAACCGTACTCGGCCATTACCGTCACCATCGAGAATCTCACCAGCGAATCCTACAGCGTC GACAGCTTCAGCGGCATCCCTGACCTGGTCGAGGTCATCAAGCTCCAGGCCACGGGCCCTACAGAGGCGGCGCGG GCCATCCGCAAGAAGCTCAAGTACGGCAATGTCCACCGCCAGCTCCGCGCCCTCGTCATTCTCGACGGGCTCATC CAGAATGCCGGATCCAACTTCCAGCGCACCTTTGCCGACGAGCCCCTGCTCGAGCGGCTCAGGGTGTGCGGCACT TCGGGCCTTTCCGACGCAGCCGTCAGGAACAAGGCCACGGAGCTTTTCCGGGAGTGGTCGCAATACGCCAACACT CCCGGGCTGGAGCGCGTCGCCCGGCTTTACAGGGAACTTCCCAAGAGAAAGGTGACGGTCACGCAAGATAAATCA AAGGTCATACGCGAGACCGAGAACCCGTTTGGAGACGACGATGAACCCGAGCCAGACCGTGGTTCACGAGCTGGG CCGGAACCGACCTCGTCAGCCAGGTCCAGCCAACACGCCGACCAGGACAAGAAGAAGAAGAAAAAGGACATCAAG CCCAGGTTTGGGAGCAGCCGCAGATCGTTTAGCCTCGAGGCGGAAAAGGAGTCGATCAAGTCCGTAATCGCCGAA GCGTCCATCGAGTCGACCAACCTGATGAACTCGCTCCAGAGCATCAACCGCGAGCGCCAGCGCATTTCGGAGAAC CGGGGGGCTGTGCAGCACTTTGACGCGTGCAAGCAGCTCCGGCGAAGGATCCTCCGCTACATCCACCTGGTTGAC AGCGAGCAATGGCTCGGCAGCCTGCTTCACGCCAACGACGAGCTCGTGCATGCCCTCATGTCGTTTGAGCAGCTG GACCGGTCCATCGATGCCGATAGCGACTCGGACGACGAGCTGGCCGAGCAAGCTCACCTCTATCGAATGAACACG GGCACGCACAGGAGCACAGCCAACCCGGCGACATCGAGTGCCCGCACCCTGGAACTGGCCGGTCTCACCCTCAAC CCTTCTCCCAAGCCGGCCCCGCCTCCAGTTCCTCGGGCGCCACAGCCGGCTCATGGGCCGCGCGTTGATCAGCTC AAGATGCCCAAGCAGGAAGAGGACGACGACCCTTTCAGCGACAACAACGTGGTAGGGACGCCACCGCTCGAGCGA GAGGAGCCCCGCTGGTAG
Gene	>Ophun1|3106 ATGCCTCATCCCGGACAAGAAACAGCTCACGATGCCAACGACATCCACCTCGAGCGCCTCCTAAAGCTGACCGAC CACGTGGCCGACGTGTTTACCCAGATTCTGAGCCATCAGAGAGACCTGCCATACCGTGTCTTGGATTCCCTCGAC AAGCAAGCTGCCAGGTTCAAGTGCTGGAGGATCGTCGCCGGCCTCTCGACATCTTCCCACCATGGCCAGGCTCTC GCCGTGGCTCGCCTTGATGATGCTCCCGCCATGAGGGGCGCCCTAATTGCTGCTCTAGAGTACCTGTGTCTTCAG TTGGGTGCCGGTGAGCGTCAGAAGTTCGGACGCTGGCCCGCAGAAGACACCGAGACATGCTCTAGCAACAGCAGA GATCGAGTCTTGTCCATGGACGCCATAAACCGAGTCGAGTCGACCATTACAACGCTCCATCAACTTTCTATTTCC AACAGGCGGACTGCTCTTCTGACCTCCACCGACCTCCTCGTTCAGTTATATCAGTCGGACAATGAAGACCCCGTG GCTGAGCTGTCCATCAGGTTGCTGTCCAAGCGAGTCTGGTCGGCCTTTAGTGCCAGCTACTTCATCCCAGACGAT GCCCTGCACACCGTCATAGACGTGGCCAGCACGGAAAGGGTCCTAGCTGCGGCGTCTCCGGAGCGCCATAGCACC AAGACAGCAGCTTGTGCGAGGACTGTTTGTCAAGATGCCGACTCCGCCGGACTGCGCCGAGTCTTTGCGGTTCTG GTACTGCTACGCAGCATCAGCGCTCTCGACGCCTTTATCCACCTCTCGCTGACTGACGGTCGTCTACCACTGCTA CCAAACGATGCCGTATGGATAGAGTTGATAGAAGCTGTTGATGGTGATACGGTTCATCGATTCGCCGAACTCCAA TGGCTGGTTCTTGCACCACGACTCATCAGGCATCATGACACCGAAACCTACTGCTTGGATCGCTCAGCTATAGTT CCTTGCCTGGAGGCTCAGGTTATACCGAAGTTTGGTGGGGATCCAGACTCAACGCAGCCAGGCCACGAACATAGA CAGCCCATCATCCTTCAGTGCAGTCCCGTGTGGAAGGTCAAGATTCATGCTGGCCACATAGCAGCGTCCCATAAG AGGGTTCGTGCCACCTTGAGGATGAAGGAAGTGAATTTGCTAAAGTCAGGCAGGATACCCCGTACTTTGCCTTCA AGCAACAACAAGGCTTGTCGGAACGGGAGGCCTTGGGGGAGATTGCCAACCTGAGAGAACTGCGATATCTCGGTC GTCCGCAAGAGCACATCATCGAGCTGCTAGACTCCTTCTTCTACAAGGATGACTTCTATCTAGTGTTTGACTGGG CAGAAGACAACCTGATGCAGTATTGGCAGCGAAATGGTGAGCCCAAGTTGACCAAGGGGTTGCTGAGATGGGCCA GCTCGCAGATATCTGGACTTACTCAGGGCCTTGCGGCGATTCACGACGAGCTGATGGGCTTCCACGGAGACATCA CGTCACACAACGTCCTCAGATTCACCGGAACAGACACCTCAAGTCCCTACGGCACCCTCAAACTGTCAGACTTTG GACTGGCACAGTTCCCTGGACGTTGCCACCAATCGGGCTCCTCCAGCGAGCGATTCTACGATCTGCATTGCGACC CGACCTACCAGTCTCCGGAGTGTCAACCGCCGGAGAGCCCGAACGATATGCCCATGAACGTCACTCAGAAGTCCG ACATCTGGCCCCTTGGCTGCGTCTACCTCAACTTCGTGACGTGGCTGGTCTGTGGCTGGACTGGGTTGGAGCAGT TTTCCCATCAACGACTGGACGAGCATGAATCGGACATGCAAGTCGACTCTTTCTTCAAAATCGAGGATGAAACAC GCCCGCGCCCCGTTCTGAAAACCTCGGTCAGCCGGAGAATGGATCAGTTCAAGAGTATCGAGTCCCAGCCAATGT TTACCCATGATCTGGTCGACGTCATACGGGACAATATGCTCCAGGTGAACCCACGGAAACGCCTCTCTTCTCGAG CCTTATGTGATTGGCTTCTGGAGTTGCATGACAAGTGCCAGAATACGCAGCGAGGCCCGGAAGATGATGAAGCGA CGCTGGTCTCCTCCCCGCGGGTCACGCAGGCTATTAAAGTGAGATATGTCAGGCGAAGTTCGCTGAAATTGTTTC TCAACGAGTTGTTTCCCGAATGCCCCGTCAAGATGAGCCACATTGACGACATGTGGATAGTTACCCTGCCGAGGA AACTCACCGAGGTAAGTTACACAGCTCGTTTGAAGCCGTTGACGCTGAGGCTTAGAGCAGGCCGACATTGAGCAT CTACGAGAAGAGTATGCAGATGGGTAGAACTCACCATGGGTCTTGTCTAAGGATGAGTTGCGGTCATGATCTTGA TGAGTCGAGATCCCGCTAGATACTTTACAAGCAGCCATCTTGCCGTAAACGGTGATTGCGGCTACCAGGAATTAC ACGTCCTGACGGTGGTGAATGAATCCCTTGAGAGGCTGGATGACGTGGACTTTTGTGAAAGTGACTGGCAATCTG CACTCGTCTATCGTTGAAAGAGCCGTGCCAAGATGCCGGCTAGTGCAGCTATTTTTGTCGGAAATCACCGTCTAT GTGTTCGTACACTTGCTGGCGAGAATTGACTGATAAAGGGAGAGGCGATCAAGGATCCATAGCGAGGCCGATGTC GTGACGATGGGATCTTGTCTTTGCACGTGACTGACGTGCCCAATTCAATTCGACTCCACGCTACCCTAGAGTCGG ACGGGTGCGGAAACCATCGAGATGGCGTCAGACATGGATTGCGTTTCACGTGGTGCAGGGGCATTGATTGTGGGC AGGCTTCTCGAACTTCTCGTATTGTGATTCGGTTACACAGCCGTCATTGTTTCTCTTTGTCATTGATCATTGTTG TCGTTTCCGTAGATGCATCATGTGTCTTGTTCCCGGAAGACGCGAACGAAGCCGCTCTCCGACGCGAGCGAGGGT CTGCCATTCCTACCTACGGGGCGCAGCCTGATGGATGATTCCAGCTTTGTAGAGGTGACGTGAGGCGCTGTTTGG TGTTTGGCCTGCCTGCCTGCCCCTCCTGTATTTTCGTAGGTGCACACGTAACGGGTCGCACCACAGACGCGCCTC GGGCCGTCTTGATTCCTTTCTGCTTCCCTAGTTCTGCTCCTCCTCATCCTCCTCCTCATCCTCATTCTCCTCATC CTCATTCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCTCTACCTACCTTCATCATCCCACCAGCTCAGCCTC GCTCGAGCCTCCTCCGCACGCCGCTCCGTCCGCCTCGTTCCCGCCCGGACCAGACCGACGTTACCGTCCGGGGCA GCTTGGAGCCTGAGCCTGAGCCTTGGGCCGACGGGAGCTCTGACGTCCAAGATAGCCCTCGTGCTTCTGCAACGA CATCGCACGGCCGCCCAGCATGTTCTCTCAGGTACGCAGACTCTTCTCGTCGCCCTGCATCCGGTCTCACTCCTC TTGCTAGAAGAAACCGTACTCGGCCATTACCGTCACCATCGAGAATCTCACCAGCGAATCCTACAGCGTCGACAG CTTCAGCGGCATCCCTGACCTGGTCGAGGTCATCAAGCTCCAGGCCACGGGCCCTACAGAGGCGGCGCGGGCCAT CCGCAAGAAGCTCAAGTACGGCAATGTCCACCGCCAGCTCCGCGCCCTCGTCATTCTCGACGGGCTCATCCAGAA TGCCGGATCCAACTTCCAGCGCACCTTTGCCGACGAGCCCCTGCTCGAGCGGCTCAGGGTGTGCGGCACTTCGGG CCTTTCCGACGCAGCCGTCAGGAACAAGGCCACGGAGCTTTTCCGGGAGTGGTCGCAATACGCCAACACTCCCGG GCTGGAGCGCGTCGCCCGGCTTTACAGGGTGAGCGCCTCTGCGTCTATCTGGGTGACGTCTATCTGATGGTGGAG CTAGGAACTTCCCAAGAGAAAGGTGACGGTCACGCAAGATAAATCAAAGGTCATACGCGAGACCGAGAACCCGTT TGGAGACGACGATGAACCCGAGCCAGACCGTGGTTCACGAGCTGGGCCGGAACCGACCTCGTCAGCCAGGTCCAG CCAACACGCCGACCAGGACAAGAAGAAGAAGAAAAAGGACATCAAGCCCAGGTTTGGGAGCAGCCGCAGATCGTT TAGCCTCGAGGCGGAAAAGGAGTCGATCAAGTCCGTAATCGCCGAAGCGTCCATCGAGTCGACCAACCTGATGAA CTCGCTCCAGAGCATCAACCGCGAGCGCCAGCGCATTTCGGAGAACCGGGGGGCTGTGCAGCACTTTGACGCGTG CAAGCAGCTCCGGCGAAGGATCCTCCGCTACGTAAGGCCCCGAATGTTGTTGCTCCGTGCGATTGTTGACTCCGG ATGGACAGATCCACCTGGTTGACAGCGAGCAATGGCTCGGCAGCCTGCTTCACGCCAACGACGAGCTCGTGCATG CCCTCATGTCGTTTGAGCAGCTGGACCGGTCCATCGATGCCGATAGCGACTCGGACGACGAGCTGGCCGAGCAAG CTCACCTCTATCGAAGTAGGCTTCTACGTATCCGGCCCCTCCTGTCATGCTGCTGACACGGGGGATTCTAGTGAA CACGGGCACGCACAGGAGCACAGCCAACCCGGCGACATCGAGTGCCCGCACCCTGGAACTGGCCGGTCTCACCCT CAACCCTTCTCCCAAGCCGGCCCCGCCTCCAGTTCCTCGGGCGCCACAGCCGGCTCATGGGCCGCGCGTTGATCA GCTCAAGATGCCCAAGCAGGAAGAGGACGACGACCCTTTCAGCGACAACAACGTGGTAGGGACGCCACCGCTCGA GCGAGAGGAGCCCCGCTGGTAG