Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophun1|2824
Gene name
Location	Contig_250:19305..23445
Strand	+
Gene length (bp)	4140
Transcript length (bp)	3234
Coding sequence length (bp)	3234
Protein length (aa)	1078

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF08214	HAT_KAT11	Histone acetylation protein	9.5E-96	10	319
PF01425	Amidase	Amidase	3.5E-09	696	796

Swissprot hits

GO

GO Term	Description	Terminal node
GO:0004402	histone acetyltransferase activity	Yes
GO:0006355	regulation of transcription, DNA-templated	Yes
GO:0016573	histone acetylation	Yes
GO:0034212	peptide N-acetyltransferase activity	No
GO:0031323	regulation of cellular metabolic process	No
GO:0019222	regulation of metabolic process	No
GO:0043170	macromolecule metabolic process	No
GO:0016410	N-acyltransferase activity	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0016740	transferase activity	No
GO:0044238	primary metabolic process	No
GO:2001141	regulation of RNA biosynthetic process	No
GO:0010468	regulation of gene expression	No
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	No
GO:0016746	acyltransferase activity	No
GO:0008080	N-acetyltransferase activity	No
GO:0060255	regulation of macromolecule metabolic process	No
GO:0018393	internal peptidyl-lysine acetylation	No
GO:0018193	peptidyl-amino acid modification	No
GO:0009889	regulation of biosynthetic process	No
GO:0018394	peptidyl-lysine acetylation	No
GO:0018205	peptidyl-lysine modification	No
GO:0008152	metabolic process	No
GO:0016407	acetyltransferase activity	No
GO:0003824	catalytic activity	No
GO:0006475	internal protein amino acid acetylation	No
GO:0031326	regulation of cellular biosynthetic process	No
GO:1903506	regulation of nucleic acid-templated transcription	No
GO:0050789	regulation of biological process	No
GO:0010556	regulation of macromolecule biosynthetic process	No
GO:0006807	nitrogen compound metabolic process	No
GO:0061733	peptide-lysine-N-acetyltransferase activity	No
GO:0080090	regulation of primary metabolic process	No
GO:0065007	biological regulation	No
GO:0051171	regulation of nitrogen compound metabolic process	No
GO:0071704	organic substance metabolic process	No
GO:0043543	protein acylation	No
GO:0051252	regulation of RNA metabolic process	No
GO:0050794	regulation of cellular process	No
GO:0008150	biological_process	No
GO:0006473	protein acetylation	No
GO:1901564	organonitrogen compound metabolic process	No
GO:0016570	histone modification	No
GO:0003674	molecular_function	No
GO:0036211	protein modification process	No
GO:0043412	macromolecule modification	No
GO:0019538	protein metabolic process	No
GO:0019219	regulation of nucleobase-containing compound metabolic process	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 12	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophun1|2824 MSDSSSSGSLRSRLAAVLPKDHRFDLFHLSTPPVKTDALCSAPPNERPDRTYCEKHFLAVSVAAPKNVLILGLEL FVYTTAYATTLFVSKADSTGCLSLLGLPKSGLSPSREICTAFIAYLVENRRRSGIQLVVSLFARAQGQYLFPGSV KHDGKHVLDDRGLVKWWCRVLDPLLDHIQSKTWARSQGYLVIPGLESVEARAFLPRMRSETGSEWLIGHPLERIS HYGREFDWVPPRCLIPRFPDDPKSRFRDELDEEAAKSGLMRNLGSWKSVKTLDTFWEVMGFRQECSSGRMTGFIW VVFDDEIAAQLNDARPQTPTRQPIGSRGIPKTTPKKLRQSVGHGSPRALTDDQQQDRDKTKKKRQRLKGAIRARQ PRIKTTRRNYFADMPSTSKYYFWPSQGRGERIVDEGDYKRIIDLLLHLDFATPDKAAGSSRRWIDEAGIGVSWGL EVTGPWRTKIGSNKEGKSVWSVGVGSARVSRLKILNQGQFRTSHHPLFAMAQPATVKSLVTCIIAGTHYLIHPQK LGTIQETIKPDALLPVTLLDTQEIFDGVDDTLRKFQSRDDVFAPDFGFILVEKPGANSSKVAHAASHSRELYSLH DDARGTAAMAADGHDESKLAVKGLAGLPSGPYFLQGPNLHQAWRLYDDTAGAFAMGVVPENVTTQETSFRAVSSL SDSGLHRSIAVPSRLYYDRISEAKPLNGLRIAISDSMALKGVSTSLSSRAWLALNPSPADTTAALAQRLIDLGAV IVGKTKSSQFASGLAWVDEHAPWSPRGDGYQRVFGGAAGAGAAIASYQWLAEALAIDGIDGLGETHALFSLRTTP GTIALNGTQISSRSYDTVGLMGRTMAGLSRIASSILTPTDSEKKLSLPGRLVFPLDMASTNISEEHQKLAKLFQR ALEKVTGHRPDTVNLTAAWDTSPPAEARGKSLHEYITHPAFRSFCYEFFNEYDGFKKEYQDSFKQPPYAEATTRY RWAPMPPGRLTPELLSWILRAPQVMVPFAQLPYESTISQRKEYHAVYGSVMGPAGGDLSALYLVREALDTARWRN VVDTGPLAFPQDYTPPDVNLLRTDLKV*
Coding	>Ophun1|2824 ATGTCGGACTCCTCTTCCTCGGGCAGTCTGCGCTCGAGGCTCGCTGCCGTGTTGCCCAAAGACCACCGCTTCGAT CTCTTCCATCTGTCGACACCCCCAGTCAAGACGGATGCCCTCTGCTCAGCGCCACCGAACGAGCGCCCAGACCGC ACGTACTGCGAGAAGCACTTCCTCGCCGTCTCCGTGGCGGCGCCTAAGAATGTCCTCATCCTCGGCCTCGAGCTC TTTGTCTACACCACGGCATATGCCACCACCCTCTTCGTGTCCAAGGCCGACTCGACCGGCTGCCTTAGCCTCCTG GGTCTTCCGAAGAGTGGGCTGAGCCCTTCACGCGAGATTTGCACCGCGTTCATTGCCTATCTGGTGGAGAACAGG CGACGCAGTGGCATACAGCTCGTCGTCAGCCTCTTTGCTCGCGCCCAAGGCCAATACCTCTTCCCCGGGAGCGTC AAGCACGACGGTAAGCATGTGCTCGACGACCGCGGTCTCGTCAAGTGGTGGTGTCGCGTCCTTGATCCACTGCTG GACCATATCCAGTCCAAGACTTGGGCGCGTAGCCAGGGCTACCTAGTCATACCCGGACTCGAATCTGTCGAAGCT CGCGCCTTTCTTCCTAGAATGCGCTCCGAAACCGGCTCTGAATGGCTCATTGGCCATCCCCTGGAGCGGATATCT CACTACGGACGAGAATTCGACTGGGTGCCGCCGCGATGCCTCATTCCCCGATTCCCCGACGATCCCAAGTCTCGG TTCCGCGACGAGCTAGACGAAGAGGCGGCCAAGTCTGGCTTGATGCGGAATTTGGGGAGTTGGAAGAGTGTCAAG ACGCTGGATACATTTTGGGAAGTCATGGGCTTTCGTCAGGAGTGCTCGAGTGGAAGAATGACGGGGTTTATCTGG GTGGTCTTTGATGATGAAATCGCCGCCCAGCTCAACGATGCAAGACCACAAACACCAACCCGACAGCCTATCGGG TCCCGCGGCATTCCCAAGACAACGCCCAAAAAGCTGCGTCAGTCCGTTGGTCATGGAAGTCCGCGGGCGTTAACC GACGATCAGCAGCAGGACAGGGACAAGACCAAGAAGAAGAGGCAAAGGTTAAAGGGCGCGATAAGAGCACGACAG CCGCGCATCAAGACGACAAGGCGCAACTATTTCGCCGACATGCCATCAACAAGCAAGTACTACTTTTGGCCGTCG CAGGGCCGAGGCGAGCGTATAGTCGACGAGGGAGACTATAAGCGCATCATCGACCTGCTTTTGCACCTCGACTTT GCAACGCCAGACAAGGCCGCCGGCAGCTCCAGGCGCTGGATCGATGAGGCAGGGATAGGCGTGTCGTGGGGCTTG GAAGTGACGGGGCCATGGCGGACCAAGATCGGCTCTAACAAGGAGGGGAAATCCGTGTGGTCGGTCGGAGTCGGA TCTGCCCGCGTGTCTCGGCTGAAGATTCTGAACCAAGGGCAATTCCGCACCAGCCATCATCCTCTCTTCGCCATG GCCCAGCCGGCTACTGTCAAATCGCTGGTGACGTGCATCATCGCAGGCACTCACTATCTCATCCATCCTCAGAAA CTGGGCACCATCCAGGAAACAATCAAGCCGGATGCTCTCCTCCCCGTCACGCTGCTGGACACGCAAGAGATCTTT GATGGCGTCGACGACACGCTGCGCAAGTTCCAGAGCCGCGATGACGTATTCGCCCCGGACTTTGGCTTCATCCTG GTCGAGAAGCCTGGCGCCAACTCGAGCAAGGTAGCCCACGCCGCATCGCACAGCAGAGAGCTATACAGCCTCCAC GACGACGCCCGCGGCACAGCTGCCATGGCGGCTGACGGCCATGACGAATCCAAACTCGCAGTGAAGGGCTTGGCC GGGCTGCCGTCTGGCCCATACTTTCTTCAAGGTCCGAACCTGCACCAGGCTTGGCGGCTGTACGATGACACGGCC GGTGCCTTCGCCATGGGTGTCGTTCCGGAGAACGTGACGACGCAGGAGACGAGCTTCCGCGCCGTCAGCTCGCTC TCCGACTCGGGCCTCCATAGATCTATAGCCGTGCCGTCGCGGCTGTATTACGACCGCATCAGCGAGGCTAAACCC CTGAACGGGCTACGAATTGCTATTTCCGATAGCATGGCCCTCAAGGGCGTTTCCACGAGTCTTTCGAGCCGAGCC TGGCTGGCCCTCAACCCATCTCCCGCGGACACCACGGCAGCACTGGCTCAGCGGCTGATTGACTTGGGAGCCGTC ATCGTCGGCAAGACCAAGTCGTCCCAGTTCGCCTCGGGGCTTGCATGGGTCGACGAACATGCACCTTGGAGTCCG CGGGGAGATGGATATCAGCGCGTGTTTGGGGGTGCAGCCGGCGCTGGGGCAGCAATTGCCTCTTACCAGTGGCTC GCAGAGGCTCTTGCAATTGATGGTATCGACGGCCTGGGTGAAACTCATGCTCTCTTCTCTCTGCGCACTACACCT GGTACCATTGCCCTGAATGGAACACAGATCAGCTCCAGATCCTATGACACTGTCGGCTTAATGGGGAGGACCATG GCCGGGCTATCTCGAATCGCCTCATCTATCTTAACTCCTACGGACAGCGAGAAGAAGCTGTCTCTGCCAGGACGA CTCGTGTTTCCCTTGGATATGGCCAGCACTAACATCAGCGAAGAACACCAGAAGCTGGCAAAGCTGTTTCAAAGG GCACTGGAGAAGGTAACTGGCCACCGGCCCGACACCGTCAACTTGACAGCAGCGTGGGACACGAGCCCTCCAGCA GAGGCCAGGGGAAAGTCTCTGCATGAATACATCACTCATCCCGCGTTTCGTTCTTTCTGCTACGAATTTTTCAAC GAATATGACGGCTTCAAAAAAGAATACCAGGACAGCTTCAAGCAGCCGCCCTATGCTGAGGCGACGACGCGATAC AGGTGGGCACCAATGCCGCCAGGACGACTCACGCCCGAGCTGCTCTCGTGGATTCTACGAGCACCCCAGGTCATG GTTCCCTTCGCCCAACTTCCGTACGAGTCCACGATCAGCCAGAGAAAGGAGTATCACGCTGTTTACGGTTCTGTC ATGGGGCCAGCAGGCGGCGATTTGTCCGCACTCTACCTCGTCCGGGAGGCGCTGGATACAGCTCGCTGGCGCAAT GTTGTAGACACGGGCCCCTTAGCGTTTCCTCAGGACTACACGCCCCCGGATGTAAATCTACTACGCACAGACTTG AAGGTATAA
Transcript	>Ophun1|2824 ATGTCGGACTCCTCTTCCTCGGGCAGTCTGCGCTCGAGGCTCGCTGCCGTGTTGCCCAAAGACCACCGCTTCGAT CTCTTCCATCTGTCGACACCCCCAGTCAAGACGGATGCCCTCTGCTCAGCGCCACCGAACGAGCGCCCAGACCGC ACGTACTGCGAGAAGCACTTCCTCGCCGTCTCCGTGGCGGCGCCTAAGAATGTCCTCATCCTCGGCCTCGAGCTC TTTGTCTACACCACGGCATATGCCACCACCCTCTTCGTGTCCAAGGCCGACTCGACCGGCTGCCTTAGCCTCCTG GGTCTTCCGAAGAGTGGGCTGAGCCCTTCACGCGAGATTTGCACCGCGTTCATTGCCTATCTGGTGGAGAACAGG CGACGCAGTGGCATACAGCTCGTCGTCAGCCTCTTTGCTCGCGCCCAAGGCCAATACCTCTTCCCCGGGAGCGTC AAGCACGACGGTAAGCATGTGCTCGACGACCGCGGTCTCGTCAAGTGGTGGTGTCGCGTCCTTGATCCACTGCTG GACCATATCCAGTCCAAGACTTGGGCGCGTAGCCAGGGCTACCTAGTCATACCCGGACTCGAATCTGTCGAAGCT CGCGCCTTTCTTCCTAGAATGCGCTCCGAAACCGGCTCTGAATGGCTCATTGGCCATCCCCTGGAGCGGATATCT CACTACGGACGAGAATTCGACTGGGTGCCGCCGCGATGCCTCATTCCCCGATTCCCCGACGATCCCAAGTCTCGG TTCCGCGACGAGCTAGACGAAGAGGCGGCCAAGTCTGGCTTGATGCGGAATTTGGGGAGTTGGAAGAGTGTCAAG ACGCTGGATACATTTTGGGAAGTCATGGGCTTTCGTCAGGAGTGCTCGAGTGGAAGAATGACGGGGTTTATCTGG GTGGTCTTTGATGATGAAATCGCCGCCCAGCTCAACGATGCAAGACCACAAACACCAACCCGACAGCCTATCGGG TCCCGCGGCATTCCCAAGACAACGCCCAAAAAGCTGCGTCAGTCCGTTGGTCATGGAAGTCCGCGGGCGTTAACC GACGATCAGCAGCAGGACAGGGACAAGACCAAGAAGAAGAGGCAAAGGTTAAAGGGCGCGATAAGAGCACGACAG CCGCGCATCAAGACGACAAGGCGCAACTATTTCGCCGACATGCCATCAACAAGCAAGTACTACTTTTGGCCGTCG CAGGGCCGAGGCGAGCGTATAGTCGACGAGGGAGACTATAAGCGCATCATCGACCTGCTTTTGCACCTCGACTTT GCAACGCCAGACAAGGCCGCCGGCAGCTCCAGGCGCTGGATCGATGAGGCAGGGATAGGCGTGTCGTGGGGCTTG GAAGTGACGGGGCCATGGCGGACCAAGATCGGCTCTAACAAGGAGGGGAAATCCGTGTGGTCGGTCGGAGTCGGA TCTGCCCGCGTGTCTCGGCTGAAGATTCTGAACCAAGGGCAATTCCGCACCAGCCATCATCCTCTCTTCGCCATG GCCCAGCCGGCTACTGTCAAATCGCTGGTGACGTGCATCATCGCAGGCACTCACTATCTCATCCATCCTCAGAAA CTGGGCACCATCCAGGAAACAATCAAGCCGGATGCTCTCCTCCCCGTCACGCTGCTGGACACGCAAGAGATCTTT GATGGCGTCGACGACACGCTGCGCAAGTTCCAGAGCCGCGATGACGTATTCGCCCCGGACTTTGGCTTCATCCTG GTCGAGAAGCCTGGCGCCAACTCGAGCAAGGTAGCCCACGCCGCATCGCACAGCAGAGAGCTATACAGCCTCCAC GACGACGCCCGCGGCACAGCTGCCATGGCGGCTGACGGCCATGACGAATCCAAACTCGCAGTGAAGGGCTTGGCC GGGCTGCCGTCTGGCCCATACTTTCTTCAAGGTCCGAACCTGCACCAGGCTTGGCGGCTGTACGATGACACGGCC GGTGCCTTCGCCATGGGTGTCGTTCCGGAGAACGTGACGACGCAGGAGACGAGCTTCCGCGCCGTCAGCTCGCTC TCCGACTCGGGCCTCCATAGATCTATAGCCGTGCCGTCGCGGCTGTATTACGACCGCATCAGCGAGGCTAAACCC CTGAACGGGCTACGAATTGCTATTTCCGATAGCATGGCCCTCAAGGGCGTTTCCACGAGTCTTTCGAGCCGAGCC TGGCTGGCCCTCAACCCATCTCCCGCGGACACCACGGCAGCACTGGCTCAGCGGCTGATTGACTTGGGAGCCGTC ATCGTCGGCAAGACCAAGTCGTCCCAGTTCGCCTCGGGGCTTGCATGGGTCGACGAACATGCACCTTGGAGTCCG CGGGGAGATGGATATCAGCGCGTGTTTGGGGGTGCAGCCGGCGCTGGGGCAGCAATTGCCTCTTACCAGTGGCTC GCAGAGGCTCTTGCAATTGATGGTATCGACGGCCTGGGTGAAACTCATGCTCTCTTCTCTCTGCGCACTACACCT GGTACCATTGCCCTGAATGGAACACAGATCAGCTCCAGATCCTATGACACTGTCGGCTTAATGGGGAGGACCATG GCCGGGCTATCTCGAATCGCCTCATCTATCTTAACTCCTACGGACAGCGAGAAGAAGCTGTCTCTGCCAGGACGA CTCGTGTTTCCCTTGGATATGGCCAGCACTAACATCAGCGAAGAACACCAGAAGCTGGCAAAGCTGTTTCAAAGG GCACTGGAGAAGGTAACTGGCCACCGGCCCGACACCGTCAACTTGACAGCAGCGTGGGACACGAGCCCTCCAGCA GAGGCCAGGGGAAAGTCTCTGCATGAATACATCACTCATCCCGCGTTTCGTTCTTTCTGCTACGAATTTTTCAAC GAATATGACGGCTTCAAAAAAGAATACCAGGACAGCTTCAAGCAGCCGCCCTATGCTGAGGCGACGACGCGATAC AGGTGGGCACCAATGCCGCCAGGACGACTCACGCCCGAGCTGCTCTCGTGGATTCTACGAGCACCCCAGGTCATG GTTCCCTTCGCCCAACTTCCGTACGAGTCCACGATCAGCCAGAGAAAGGAGTATCACGCTGTTTACGGTTCTGTC ATGGGGCCAGCAGGCGGCGATTTGTCCGCACTCTACCTCGTCCGGGAGGCGCTGGATACAGCTCGCTGGCGCAAT GTTGTAGACACGGGCCCCTTAGCGTTTCCTCAGGACTACACGCCCCCGGATGTAAATCTACTACGCACAGACTTG AAGGTATAA
Gene	>Ophun1|2824 ATGTCGGACTCCTCTTCCTCGGGCAGTCTGCGCTCGAGGCTCGCTGCCGTGTTGCCCAAAGACCACCGCTTCGAT CTCTTCCATCTGTCGACACCCCCAGTCAAGACGGATGCCCTCTGCTCAGCGCCACCGAACGAGCGCCCAGACCGC ACGTACTGCGAGAAGCACTTCCTCGCCGTCTCCGTGGCGGCGCCTAAGAATGTCCTCATCCTCGGCCTCGAGCTC TTTGTCTACACCACGGCATATGCCACCACCCTCTTCGTGTCCAAGGCCGACTCGACCGGCTGCCTTAGCCTCCTG GGTCTTCCGAAGAGTGGGCTGAGCCCTTCACGCGAGATTTGCACCGCGTTCATTGCCTATCTGGTGGAGAACAGG CGACGCAGTGGCATACAGCTCGTCGTCAGCCTCTTTGCTCGCGCCCAAGGCCAATACCTCTTCCCCGGGAGCGTC AAGCACGACGGTAAGCATGTGCTCGACGACCGCGGTCTCGTCAAGTGGTGGTGTCGCGTCCTTGATCCACTGCTG GACCATATCCAGTCCAAGACTTGGGCGCGTAGCCAGGGCTACCTAGTCATACCCGGACTCGAATCTGTCGAAGCT CGCGCCTTTCTTCCTAGAATGCGCTCCGAAACCGGCTCTGAATGGCTCATTGGCCATCCCCTGGAGCGGATATCT CACTACGGACGAGAATTCGACTGGGTGCCGCCGCGATGCCTCATTCCCCGATTCCCCGACGATCCCAAGTCTCGG TTCCGCGACGAGCTAGACGAAGAGGCGGCCAAGTCTGGCTTGATGCGGAATTTGGGGAGTTGGAAGAGTGTCAAG ACGCTGGATACATTTTGGGAAGTCATGGGCTTTCGTCAGGAGTGCTCGAGTGGAAGAATGACGGGGTTTATCTGG GTGGTCTTTGATGATGAAATCGCCGCCCAGCTCAACGATGCAAGACCACAAACACCAACCCGACAGCCTATCGGG TCCCGCGGCATTCCCAAGACAACGCCCAAAAAGCTGCGTCAGTCCGTTGGTCATGGAAGTCCGCGGGCGTTAACC GACGATCAGCAGCAGGACAGGGACAAGACCAAGAAGAAGAGGCAAAGGTTAAAGGGCGCGATAAGAGCACGACAG CCGCGCATCAAGACGACAAGGCGCAACTATTTCGCCGACATGCCATCAACAAGCAAGTACTACTTTTGGCCGTCG CAGGGCCGAGGCGAGCGTATAGTCGACGAGGGAGACTATAAGCGCATCATCGACCTGCTTTTGCACCTCGACTTT GCAACGCCAGACAAGGCCGCCGGCAGCTCCAGGCGCTGGATCGATGAGGCAGGGATAGGCGTGTCGTGGGGCTTG GAAGTGACGGGGTTGAGAGAGTTGCCACCGGCGACGGAAGCTCCAAGCGACGAGGTTCAGAAAAGGGAACGAGTT AATAACCTATCTGGGCTTGTCAAGAGAAAGAGATGACTATGACAAGCTATCATGAGGCCAGTGGTGGTGATGTAG CACCAATGTTTGGTTTGGTAGGATTGGATTGAACATTTGTACGAATACAACGGTCGAGACCGAAGTCGGGGGTCT TCGGCCGGTGCCCAGGCCAATCTGCATCGCGGACACGAGCGTCGTAACCATGAGACAGGCCATGGCGGACCAAGA TCGGCTCTAACAAGGAGGGGAAATCCGTGTGGTCGGTCGGAGTCGGATCTGCCCGCGTGTCTCGGCTGAAGATTC TGAACCAAGGGCAATTCCGCACCAGCCATCATCCTCTCTTCGCCATGGCCCAGCCGGCTACTGTCAAATCGCTGG TGACGTGCATCATCGCAGGCACTCACTATCTCATCCATCCTCAGAAACTGGTACGAAGTCGGTCAACCCCCTGTA GCGACCCCTGCTGACGGTGCCGTCTCTTTTCAGGGCACCATCCAGGAAACAATCAAGCCGGATGCTCTCCTCCCC GTCACGCTGCTGGACACGCAAGAGATCTTTGATGGCGTCGACGACACGCTGCGCAAGTTCCAGAGCCGCGATGAC GTATTCGCCCCGGACTTTGGCTTCATCCTGGTCGAGAAGCCTGGCGCCAACTCGAGCAAGGTAGCCCACGCCGCA TCGCACAGCAGAGAGCTATACAGCCTCCACGACGACGCCCGCGGCACAGCTGCCATGGCGGCTGACGGCCATGAC GAATCCAAACTCGCAGTGAAGGGCTTGGCCGGGCTGCCGTCTGGCCCATACTTTCTTCAAGGTCCGAACCTGCAC CAGGCTTGGCGGCTGTACGATGACACGGCCGGTGCCTTCGCCATGGGTGTCGTTCCGGAGAACGTGACGACGCAG GAGACGAGGTATGGATACACCTTCCGAGCGTTTAGCCATGACCCTCGGACGCTCAGATGGCTCGCCCAGCTTCCG CGCCGTCAGCTCGCTCTCCGACTCGGGCCTCCATAGATCTATAGCCGTGCCGTCGCGGCTGTATTACGACCGCAT CAGCGAGGCTAAACCCCTGAACGGGCTACGAATTGCTATTTCCGATAGCATGGCCCTCAAGGGCGTTTCCACGAG TCTTTCGAGCCGAGCCTGGCTGGCCCTCAACCCATCTCCCGCGGACACCACGGCAGCACTGGCTCAGCGGCTGAT TGACTTGGGAGCCGTCATCGTCGGCAAGACCAAGTCGTCCCAGTTCGCCTCGGGGCTTGCATGGGTCGACGAACA TGCACCTTGGAGTCCGCGGGGAGATGGATATCAGCGCGTGTTTGGGGGTGCAGCCGGCGCTGGGGCAGCAATTGC CTCTTACCAGTGGCTCGCAGAGGCTCTTGCAATTGATGGTCAGCCAGATGTCGGGTCAGGTTCGACTACACCGCT GACCCAGAACAGGTATCGACGGCCTGGGTGAAACTCATGCTCTCTTCTCTCTGCGCACTACACCTGGTACCATTG CCCTGAATGGAACACAGATCAGCTCCAGGTGAGCCCTGGCTGCACTATTTTGCTCTCGCCATCCTGACGAGTGAC AGATCCTATGACACTGTCGGCTTAATGGGGAGGACCATGGCCGGGCTATCTCGAATCGCCTCATCTATCTTAACT CCTACGGACAGCGAGAAGAAGCTGTCTCTGCCAGGACGACTCGTGTTTCCCTTGGATATGGCCAGCACTAACATC AGCGAAGAACACCAGAAGCTGGCAAAGCTGTTTCAAAGGGCACTGGAGAAGGTAACTGGCCACCGGCCCGACACC GTCAACTTGACAGCAGCGTGGGACACGAGCCCTCCAGCAGAGGCCAGGGGAAAGTCTCTGCATGAATACATCACT CATGTTAGCGTTGAATCCTGCCAAGATTCATACCCTCGCTGACTGATAAATACATAGCCCGCGTTTCGTTCTTTC TGCTACGAATTTTTCAACGAATATGACGGCTTCAAAAAAGAATACCAGGACAGCTTCAAGCAGCCGCCCTATGCT GAGGCGACGACGCGATACAGGTGGTAAGCTAAGCCAACTCCCTTCAGCACGACAGCTATCGATGACTTGGACATT TTAGGGAAACTGGCAAGACTGTGTCAAAACAGGAATACGAAACGAACCAGGAGCAACTCGCTGTATTTCGCAAAT GGTTCGAGAGCAACATCTCGGCCCAGAACAACTCTACCGATAGCTGGACGGCCGTAGTCGTGCCTGCTATGAGTG AGAGACCTAGCTACAGAGACGAGGCGGCACCGTCAGTCATCCATCACCAGATAGACTGCCCTCTTCTCATGACCA AAACATTCCAGCTGACGCCTGATACTGCCAGGGCACCAATGCCGCCAGGACGACTCACGCCCGAGCTGCTCTCGT GGATTCTACGAGCACCCCAGGTCATGGTTCCCTGTAAGCCAACGAATGAATCCATCGTGGCTGCCACAAGTGCTT ACAGGTGTCACAGTCGCCCAACTTCCGTACGAGTCCACGATCAGCCAGAGAAAGGAGTATCACGCTGTTTACGGT TCTGTCATGGGGCCAGCAGGCGGCGATTTGTCCGCACTCTACCTCGTCCGGGAGGCGCTGGATACAGCTCGCTGG CGCAATGTTGTAGACACGGGCCCCTTAGCGTTTCCTCAGGACTACACGCCCCCGGATGTAAATCTACTACGCACA GACTTGAAGGTATAA