© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Ophun1|2650 |
| Gene name | |
| Location | Contig_237:13914..17522 |
| Strand | - |
| Gene length (bp) | 3608 |
| Transcript length (bp) | 3321 |
| Coding sequence length (bp) | 3321 |
| Protein length (aa) | 1107 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF13513 | HEAT_EZ | HEAT-like repeat | 1.0E-07 | 359 | 407 |
| PF02985 | HEAT | HEAT repeat | 2.8E-03 | 386 | 414 |
| PF03810 | IBN_N | Importin-beta N-terminal domain | 1.4E-05 | 30 | 89 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O60100|IMB4_SCHPO | Probable importin subunit beta-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap123 PE=3 SV=1 | 6 | 1103 | 2.0E-166 |
| sp|P40069|IMB4_YEAST | Importin subunit beta-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP123 PE=1 SV=1 | 1 | 1078 | 9.0E-125 |
| sp|Q8TEX9|IPO4_HUMAN | Importin-4 OS=Homo sapiens GN=IPO4 PE=1 SV=2 | 16 | 1064 | 4.0E-43 |
| sp|Q8VI75|IPO4_MOUSE | Importin-4 OS=Mus musculus GN=Ipo4 PE=1 SV=1 | 1 | 626 | 1.0E-29 |
| sp|O74476|IMB3_SCHPO | Importin subunit beta-3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sal3 PE=3 SV=1 | 6 | 605 | 3.0E-21 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O60100|IMB4_SCHPO | Probable importin subunit beta-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap123 PE=3 SV=1 | 6 | 1103 | 2.0E-166 |
| sp|P40069|IMB4_YEAST | Importin subunit beta-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP123 PE=1 SV=1 | 1 | 1078 | 9.0E-125 |
| sp|Q8TEX9|IPO4_HUMAN | Importin-4 OS=Homo sapiens GN=IPO4 PE=1 SV=2 | 16 | 1064 | 4.0E-43 |
| sp|Q8VI75|IPO4_MOUSE | Importin-4 OS=Mus musculus GN=Ipo4 PE=1 SV=1 | 1 | 626 | 1.0E-29 |
| sp|O74476|IMB3_SCHPO | Importin subunit beta-3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sal3 PE=3 SV=1 | 6 | 605 | 3.0E-21 |
| sp|O00410|IPO5_HUMAN | Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4 | 21 | 1048 | 2.0E-17 |
| sp|Q8BKC5|IPO5_MOUSE | Importin-5 OS=Mus musculus GN=Ipo5 PE=1 SV=3 | 21 | 1048 | 1.0E-16 |
| sp|Q8BIV3|RNBP6_MOUSE | Ran-binding protein 6 OS=Mus musculus GN=Ranbp6 PE=1 SV=3 | 2 | 602 | 4.0E-13 |
| sp|P32337|IMB3_YEAST | Importin subunit beta-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSE1 PE=1 SV=2 | 63 | 565 | 4.0E-10 |
| sp|Q8VI75|IPO4_MOUSE | Importin-4 OS=Mus musculus GN=Ipo4 PE=1 SV=1 | 790 | 1075 | 2.0E-09 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0006886 | intracellular protein transport | Yes |
| GO:0031267 | small GTPase binding | Yes |
| GO:0005515 | protein binding | Yes |
| GO:0019899 | enzyme binding | No |
| GO:0006810 | transport | No |
| GO:0009987 | cellular process | No |
| GO:0008104 | protein localization | No |
| GO:0046907 | intracellular transport | No |
| GO:0051234 | establishment of localization | No |
| GO:0051649 | establishment of localization in cell | No |
| GO:0071705 | nitrogen compound transport | No |
| GO:0033036 | macromolecule localization | No |
| GO:0051179 | localization | No |
| GO:0071702 | organic substance transport | No |
| GO:0070727 | cellular macromolecule localization | No |
| GO:0015031 | protein transport | No |
| GO:0003674 | molecular_function | No |
| GO:0045184 | establishment of protein localization | No |
| GO:0005488 | binding | No |
| GO:0008150 | biological_process | No |
| GO:0051020 | GTPase binding | No |
| GO:0051641 | cellular localization | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 51 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Ophun1|2650 MDKDRLVQLLQASQVPNTEQVKAVTADLQKNFYSQPESLLLLIEVTLTHADGALRQLAAVQALRLVSKHWKPTPE DKKALARSHLLDGTLKETSLSIRHSMARLLAGIVGIDLELGQGDDFLKQLLPLNNSDNVVAREVGSFILFSMLED DPTHFSGYIPQLLQLFRSRIKDPDSKEVQINIVQAISAMLLILDPEENPEGLATMQSFMPDLVNILKVAVEVGDD EGYRTVFEVFHSFLAYDPALLSVHLHDLLQFMIDLAANADAEEDARTQALGFLIQCVRYRRMKIQGMKDMGAQLM VKAMQIVGSLDADDDDEDLSPARTAISLINTLASELPPRQVVVPLLDQFPSYATSSHPGLRMASVLALGNAAEGA PDFVSTQLQPLLPTILNLLCDSDGQVRHAALVGLIHLAEEMADEMASKHEEIISAVLNNLEAAAQGPSDKQKVSI IRSACGALDTFGDGVDTKIMAQFGPSLIGPMVKLLDHDDFGVKAAAASAIGAIASSMGNAFEPYFKGVMEALAKF VMLKDDDDAMNLRSSTCDSLGRIAMSVGADAFQPYVMDLMKASEEALSLDNPRLKETSFILWSNLSKVYREQFNH FLDGVFKGIFASLELEETELEIPDVDPSLLADGAIFGGKRVKLKSADDMATAIDEGEWDDLDSMEDLGAVTAVAL EQEIALEVLGDVVTNCCNSANLETYAEKVIEKVQPFAGHSYEGCRKTAISTLWRTYARVFQVWESSTGVKWQPGM PPNPLPPPSIVSMADMLYKTTTTMWSEDSERRLTQTRNAVAEKTSVVTDINRNVAATLRACGPAVLAGGQEMLSE VVSVVGSIITRSHPCQQDLGEEEEERDIDGGSSEYDWLVIDTAMDVVIGLAAALGASFGELWKIFDKPILKLVSS SEELHRSTAVGTIAEVTKFAGEGISPYTESLGQALGRRLTDPDPLTKSNAAYAMGLLVLKSNETSKTVPLFPQLW EKLEPLLTTKEVRTTDNVAGCLARMMMKHSDKDFVSQALPAVVDVLPLTEDYEENEPIFQCIYSLYERGNDTVER LTPQLIGIFEKVLSPPEEQLEAETREVLRTTVQTIYKAKPELLSAHPGLLQLMGAH* |
| Coding | >Ophun1|2650 ATGGATAAGGACAGGCTCGTGCAGCTGCTACAGGCCAGCCAAGTTCCCAACACTGAGCAGGTCAAGGCCGTGACG GCAGACCTCCAGAAGAACTTCTACTCGCAGCCCGAGTCGCTTCTGCTGCTCATCGAAGTCACACTGACCCACGCA GATGGCGCTCTTCGACAGCTCGCCGCCGTTCAGGCCCTCCGCCTCGTCAGCAAGCACTGGAAGCCGACGCCGGAG GACAAGAAAGCCTTGGCCCGCTCTCACCTCCTCGACGGCACTCTCAAGGAAACGTCGCTGAGCATCCGTCACTCC ATGGCCCGTCTCTTGGCCGGCATCGTCGGCATCGACCTGGAGCTCGGACAGGGCGACGACTTTCTCAAACAGCTG CTGCCCCTCAACAACAGCGACAATGTCGTCGCCCGCGAAGTCGGCTCCTTCATCCTCTTCTCCATGCTCGAGGAT GATCCCACCCATTTCAGTGGCTACATCCCTCAGCTGCTCCAGCTCTTCCGTTCCCGCATCAAGGATCCTGACAGT AAGGAAGTGCAGATCAACATCGTCCAGGCCATCAGTGCCATGCTTCTCATCCTCGATCCCGAAGAGAATCCAGAG GGCCTCGCCACCATGCAGAGCTTCATGCCGGATCTCGTCAACATTCTCAAGGTTGCCGTCGAGGTCGGTGACGAC GAGGGCTACAGGACCGTCTTTGAAGTCTTCCATTCTTTTCTCGCCTACGACCCGGCCCTGCTGTCTGTCCATTTG CACGACCTCTTGCAGTTCATGATTGATCTAGCCGCCAACGCAGATGCCGAGGAGGACGCCCGCACCCAGGCCCTC GGCTTCCTCATCCAGTGTGTGCGCTACCGCCGCATGAAGATCCAAGGCATGAAGGACATGGGCGCCCAGCTCATG GTCAAGGCCATGCAGATCGTTGGTTCGCTCGATGCCGACGACGATGATGAGGACCTGTCGCCCGCTCGCACCGCC ATCAGTCTCATCAACACGCTGGCCAGCGAGCTACCTCCCCGTCAGGTCGTCGTACCGCTGCTCGACCAGTTCCCG TCGTACGCGACCAGCTCTCACCCCGGCTTGCGTATGGCCTCCGTGCTGGCCCTCGGCAACGCCGCCGAGGGTGCC CCCGACTTCGTCTCGACTCAGCTGCAGCCACTCTTGCCCACCATTTTGAACCTTCTCTGCGATTCCGACGGTCAA GTCCGTCACGCCGCCCTCGTTGGTCTCATCCACCTAGCCGAGGAAATGGCCGACGAGATGGCCTCCAAGCACGAG GAGATCATCTCTGCCGTTCTCAACAACCTCGAGGCCGCCGCCCAGGGCCCGTCGGATAAGCAAAAGGTCAGCATC ATTCGCAGCGCCTGTGGTGCCTTAGATACCTTTGGCGACGGCGTCGACACCAAGATCATGGCCCAGTTCGGTCCC AGCCTCATTGGGCCCATGGTCAAGCTCCTCGACCACGACGACTTTGGGGTCAAGGCTGCGGCTGCCTCTGCCATT GGCGCCATTGCGTCGTCGATGGGCAACGCTTTCGAGCCCTACTTCAAGGGAGTCATGGAAGCCCTCGCCAAGTTT GTCATGCTCAAGGACGACGACGATGCCATGAATTTGCGGAGCTCGACCTGCGACAGCCTGGGTCGCATCGCCATG TCGGTCGGTGCCGATGCATTCCAGCCATACGTAATGGATCTCATGAAGGCGAGCGAAGAGGCCCTCTCCCTCGAC AATCCAAGGCTCAAGGAGACGAGCTTCATCCTCTGGTCCAACCTGTCCAAGGTGTACCGCGAGCAGTTCAACCAT TTCCTCGATGGTGTCTTCAAGGGCATCTTTGCCTCCCTCGAACTCGAGGAGACTGAGCTGGAGATCCCCGACGTC GACCCTAGCCTGCTGGCCGACGGCGCCATCTTCGGTGGCAAGCGAGTCAAGCTAAAGTCGGCAGACGACATGGCC ACGGCCATCGACGAAGGTGAATGGGACGACCTCGATAGCATGGAGGATCTCGGCGCCGTCACCGCCGTCGCCCTG GAACAAGAGATAGCGCTCGAGGTTCTGGGCGATGTCGTCACCAACTGCTGCAACAGCGCCAACCTCGAGACGTAT GCCGAAAAGGTCATCGAAAAGGTGCAACCCTTTGCCGGACACAGCTACGAGGGCTGCCGCAAGACGGCCATCTCC ACCCTCTGGCGCACCTACGCCCGTGTCTTTCAGGTGTGGGAGAGCAGCACGGGCGTCAAGTGGCAGCCTGGCATG CCCCCCAACCCGTTGCCCCCGCCGTCCATCGTCAGCATGGCAGACATGCTATACAAGACGACGACGACTATGTGG AGCGAGGACAGTGAAAGGCGACTCACTCAGACGCGAAACGCGGTTGCTGAGAAAACGTCGGTCGTTACAGACATC AATCGCAACGTCGCCGCCACACTGAGAGCCTGTGGTCCGGCTGTGCTGGCTGGAGGCCAGGAAATGCTATCAGAG GTGGTTTCTGTCGTCGGCAGCATCATCACCCGGTCGCATCCCTGCCAGCAAGACTTGGGAGAGGAAGAAGAGGAG CGTGATATCGACGGCGGATCGTCGGAATATGACTGGCTCGTCATCGATACCGCCATGGACGTGGTCATTGGTCTC GCCGCGGCTCTGGGCGCTTCATTTGGCGAGCTGTGGAAGATCTTTGACAAGCCCATCCTGAAGCTGGTCAGCTCT TCCGAGGAGCTGCACCGGTCCACGGCCGTCGGCACCATTGCCGAGGTGACCAAGTTTGCGGGCGAGGGCATCTCG CCCTATACCGAGTCGCTGGGCCAAGCATTGGGCCGTCGTCTTACGGACCCCGACCCTCTTACCAAGTCGAACGCG GCCTACGCCATGGGCCTCTTGGTCTTAAAGTCGAACGAGACCAGCAAGACTGTGCCCCTCTTCCCGCAGCTCTGG GAGAAGCTGGAGCCGCTGCTGACGACAAAGGAGGTGCGCACGACGGACAACGTCGCTGGCTGCCTTGCGCGTATG ATGATGAAGCACTCGGACAAGGACTTTGTCTCTCAAGCGCTCCCTGCCGTCGTCGACGTGCTCCCCCTGACGGAG GACTACGAAGAGAACGAGCCCATCTTCCAGTGCATATACAGCCTCTACGAGCGAGGCAACGATACGGTCGAGCGA CTGACGCCGCAGCTGATTGGCATCTTCGAAAAGGTCTTGAGTCCGCCCGAGGAGCAGCTGGAAGCGGAGACGCGC GAGGTGCTGCGTACGACGGTGCAGACCATCTACAAGGCGAAGCCGGAGCTGCTGTCGGCTCATCCGGGGCTGCTG CAGCTGATGGGTGCTCACTAG |
| Transcript | >Ophun1|2650 ATGGATAAGGACAGGCTCGTGCAGCTGCTACAGGCCAGCCAAGTTCCCAACACTGAGCAGGTCAAGGCCGTGACG GCAGACCTCCAGAAGAACTTCTACTCGCAGCCCGAGTCGCTTCTGCTGCTCATCGAAGTCACACTGACCCACGCA GATGGCGCTCTTCGACAGCTCGCCGCCGTTCAGGCCCTCCGCCTCGTCAGCAAGCACTGGAAGCCGACGCCGGAG GACAAGAAAGCCTTGGCCCGCTCTCACCTCCTCGACGGCACTCTCAAGGAAACGTCGCTGAGCATCCGTCACTCC ATGGCCCGTCTCTTGGCCGGCATCGTCGGCATCGACCTGGAGCTCGGACAGGGCGACGACTTTCTCAAACAGCTG CTGCCCCTCAACAACAGCGACAATGTCGTCGCCCGCGAAGTCGGCTCCTTCATCCTCTTCTCCATGCTCGAGGAT GATCCCACCCATTTCAGTGGCTACATCCCTCAGCTGCTCCAGCTCTTCCGTTCCCGCATCAAGGATCCTGACAGT AAGGAAGTGCAGATCAACATCGTCCAGGCCATCAGTGCCATGCTTCTCATCCTCGATCCCGAAGAGAATCCAGAG GGCCTCGCCACCATGCAGAGCTTCATGCCGGATCTCGTCAACATTCTCAAGGTTGCCGTCGAGGTCGGTGACGAC GAGGGCTACAGGACCGTCTTTGAAGTCTTCCATTCTTTTCTCGCCTACGACCCGGCCCTGCTGTCTGTCCATTTG CACGACCTCTTGCAGTTCATGATTGATCTAGCCGCCAACGCAGATGCCGAGGAGGACGCCCGCACCCAGGCCCTC GGCTTCCTCATCCAGTGTGTGCGCTACCGCCGCATGAAGATCCAAGGCATGAAGGACATGGGCGCCCAGCTCATG GTCAAGGCCATGCAGATCGTTGGTTCGCTCGATGCCGACGACGATGATGAGGACCTGTCGCCCGCTCGCACCGCC ATCAGTCTCATCAACACGCTGGCCAGCGAGCTACCTCCCCGTCAGGTCGTCGTACCGCTGCTCGACCAGTTCCCG TCGTACGCGACCAGCTCTCACCCCGGCTTGCGTATGGCCTCCGTGCTGGCCCTCGGCAACGCCGCCGAGGGTGCC CCCGACTTCGTCTCGACTCAGCTGCAGCCACTCTTGCCCACCATTTTGAACCTTCTCTGCGATTCCGACGGTCAA GTCCGTCACGCCGCCCTCGTTGGTCTCATCCACCTAGCCGAGGAAATGGCCGACGAGATGGCCTCCAAGCACGAG GAGATCATCTCTGCCGTTCTCAACAACCTCGAGGCCGCCGCCCAGGGCCCGTCGGATAAGCAAAAGGTCAGCATC ATTCGCAGCGCCTGTGGTGCCTTAGATACCTTTGGCGACGGCGTCGACACCAAGATCATGGCCCAGTTCGGTCCC AGCCTCATTGGGCCCATGGTCAAGCTCCTCGACCACGACGACTTTGGGGTCAAGGCTGCGGCTGCCTCTGCCATT GGCGCCATTGCGTCGTCGATGGGCAACGCTTTCGAGCCCTACTTCAAGGGAGTCATGGAAGCCCTCGCCAAGTTT GTCATGCTCAAGGACGACGACGATGCCATGAATTTGCGGAGCTCGACCTGCGACAGCCTGGGTCGCATCGCCATG TCGGTCGGTGCCGATGCATTCCAGCCATACGTAATGGATCTCATGAAGGCGAGCGAAGAGGCCCTCTCCCTCGAC AATCCAAGGCTCAAGGAGACGAGCTTCATCCTCTGGTCCAACCTGTCCAAGGTGTACCGCGAGCAGTTCAACCAT TTCCTCGATGGTGTCTTCAAGGGCATCTTTGCCTCCCTCGAACTCGAGGAGACTGAGCTGGAGATCCCCGACGTC GACCCTAGCCTGCTGGCCGACGGCGCCATCTTCGGTGGCAAGCGAGTCAAGCTAAAGTCGGCAGACGACATGGCC ACGGCCATCGACGAAGGTGAATGGGACGACCTCGATAGCATGGAGGATCTCGGCGCCGTCACCGCCGTCGCCCTG GAACAAGAGATAGCGCTCGAGGTTCTGGGCGATGTCGTCACCAACTGCTGCAACAGCGCCAACCTCGAGACGTAT GCCGAAAAGGTCATCGAAAAGGTGCAACCCTTTGCCGGACACAGCTACGAGGGCTGCCGCAAGACGGCCATCTCC ACCCTCTGGCGCACCTACGCCCGTGTCTTTCAGGTGTGGGAGAGCAGCACGGGCGTCAAGTGGCAGCCTGGCATG CCCCCCAACCCGTTGCCCCCGCCGTCCATCGTCAGCATGGCAGACATGCTATACAAGACGACGACGACTATGTGG AGCGAGGACAGTGAAAGGCGACTCACTCAGACGCGAAACGCGGTTGCTGAGAAAACGTCGGTCGTTACAGACATC AATCGCAACGTCGCCGCCACACTGAGAGCCTGTGGTCCGGCTGTGCTGGCTGGAGGCCAGGAAATGCTATCAGAG GTGGTTTCTGTCGTCGGCAGCATCATCACCCGGTCGCATCCCTGCCAGCAAGACTTGGGAGAGGAAGAAGAGGAG CGTGATATCGACGGCGGATCGTCGGAATATGACTGGCTCGTCATCGATACCGCCATGGACGTGGTCATTGGTCTC GCCGCGGCTCTGGGCGCTTCATTTGGCGAGCTGTGGAAGATCTTTGACAAGCCCATCCTGAAGCTGGTCAGCTCT TCCGAGGAGCTGCACCGGTCCACGGCCGTCGGCACCATTGCCGAGGTGACCAAGTTTGCGGGCGAGGGCATCTCG CCCTATACCGAGTCGCTGGGCCAAGCATTGGGCCGTCGTCTTACGGACCCCGACCCTCTTACCAAGTCGAACGCG GCCTACGCCATGGGCCTCTTGGTCTTAAAGTCGAACGAGACCAGCAAGACTGTGCCCCTCTTCCCGCAGCTCTGG GAGAAGCTGGAGCCGCTGCTGACGACAAAGGAGGTGCGCACGACGGACAACGTCGCTGGCTGCCTTGCGCGTATG ATGATGAAGCACTCGGACAAGGACTTTGTCTCTCAAGCGCTCCCTGCCGTCGTCGACGTGCTCCCCCTGACGGAG GACTACGAAGAGAACGAGCCCATCTTCCAGTGCATATACAGCCTCTACGAGCGAGGCAACGATACGGTCGAGCGA CTGACGCCGCAGCTGATTGGCATCTTCGAAAAGGTCTTGAGTCCGCCCGAGGAGCAGCTGGAAGCGGAGACGCGC GAGGTGCTGCGTACGACGGTGCAGACCATCTACAAGGCGAAGCCGGAGCTGCTGTCGGCTCATCCGGGGCTGCTG CAGCTGATGGGTGCTCACTAG |
| Gene | >Ophun1|2650 ATGGATAAGGACAGGCTCGTGCAGCTGCTACAGGCCAGCCAAGTTCGTGAGTCGCCGCTTCCCCCTTCCGCTATT CCGTCTCTTGCCTGACCTGACCTATTCGTACTCTAGCCAACACTGAGCAGGTCAAGGCCGTGACGGCAGACCTCC AGAAGAACTTCTACTCGCAGCCCGAGTCGCTTCTGCTGCTCATCGAAGTCACACTGACCCACGCAGATGGCGCTC TTCGACAGCTCGCCGCCGTTCAGGCCCTCCGCCTCGTCAGCAAGCACTGGAAGCCGACGCCGGAGGACAAGAAAG CCTTGGCCCGCTCTCACCTCCTCGACGGCACTCTCAAGGAAACGTCGCTGAGCATCCGTCACTCCATGGCCCGTC TCTTGGCCGGCATCGTCGGCATCGACCTGGAGCTCGGACAGGGCGACGACTTTCTCAAACAGCTGCTGCCCCTCA ACAACAGCGACAATGTCGTCGCCCGCGAAGTCGGCTCCTTCATCCTCTTCTCCATGCTCGAGGATGATCCCACCC ATTTCAGTGGCTACATCCCTCAGCTGCTCCAGCTCTTCCGTTCCCGCATCAAGGATCCTGACAGTAAGGAAGTGC AGATCAACATCGTCCAGGCCATCAGTGCCATGCTTCTCATCCTCGATCCCGAAGAGAATCCAGAGGGCCTCGCCA CCATGCAGAGCTTCATGCCGGATCTCGTCAACATTCTCAAGGTTGCCGTCGAGGTCGGTGACGACGAGGGCTACA GGACCGTCTTTGAAGTCTTCCATTCTTTTCTCGCCTACGACCCGGCCCTGCTGTCTGTCCATTTGCACGACCTCT TGCAGTTCATGATTGATCTAGCCGCCAACGCAGATGCCGAGGAGGACGCCCGCACCCAGGCCCTCGGCTTCCTCA TCCAGTGTGTGCGCTACCGCCGCATGAAGATCCAAGGCATGAAGGACATGGGCGCCCAGCTCATGGTCAAGGCCA TGCAGATCGTTGGTTCGCTCGATGCCGACGACGATGATGAGGACCTGTCGCCCGCTCGCACCGCCATCAGTCTCA TCAACACGCTGGCCAGCGAGCTACCTCCCCGTCAGGTCGTCGTACCGCTGCTCGACCAGTTCCCGTCGTACGCGA CCAGCTCTCACCCCGGCTTGCGTATGGCCTCCGTGCTGGCCCTCGGCAACGCCGCCGAGGGTGCCCCCGACTTCG TCTCGACTCAGCTGCAGCCACTCTTGCCCACCATTTTGAACCTTCTCTGCGATTCCGACGGTCAAGTCCGTCACG CCGCCCTCGTTGGTCTCATCCACCTAGCCGAGGAAATGGCCGACGAGATGGCCTCCAAGCACGAGGAGATCATCT CTGCCGTTCTCAACAACCTCGAGGCCGCCGCCCAGGGCCCGTCGGATAAGCAAAAGGTCAGCATCATTCGCAGCG CCTGTGGTGCCTTAGATACCTTTGGCGACGGCGTCGACACCAAGATCATGGCCCAGTTCGGTCCCAGCCTCATTG GGCCCATGGTCAAGCTCCTCGACCACGACGACTTTGGGGTCAAGGCTGCGGCTGCCTCTGCCATTGGCGCCATTG CGTCGTCGATGGGCAACGCTTTCGAGCCCTACTTCAAGGGAGTCATGGAAGCCCTCGCCAAGTTTGTCATGCTCA AGGACGACGACGATGCCATGAATTTGCGGAGCTCGACCTGCGACAGCCTGGGTCGCATCGCCATGTCGGTCGGTG CCGATGCATTCCAGCCATACGTAATGGATCTCATGAAGGCGAGCGAAGAGGCCCTCTCCCTCGACAATCCAAGGC TCAAGGAGACGAGCTTCATCCTCTGGTCCAACCTGTCCAAGGTGTACCGCGAGCAGTTCAACCATTTCCTCGATG GTGTCTTCAAGGGCATCTTTGCCTCCCTCGAACTCGAGGAGACTGAGCTGGAGATCCCCGACGTCGACCCTAGCC TGCTGGCCGACGGCGCCATCTTCGGTGGCAAGCGAGTCAAGCTAAAGTCGGCAGACGACATGGCCACGGCCATCG ACGAAGGTGAATGGGACGACCTCGATAGCATGGAGGATCTCGGCGCCGTCACCGCCGTCGCCCTGGAACAAGAGA TAGCGCTCGAGGTTCTGGGCGATGTCGTCACCAACTGCTGCAACAGCGCCAACCTCGAGACGTATGCCGAAAAGG TCATCGAAAAGGTGCAACCCTTTGCCGGACACAGCTACGAGGGCTGCCGCAAGACGGCCATCTCCACCCTCTGGC GCACCTACGCCCGTGTCTTTCAGGTGTGGGAGAGCAGCACGGGCGTCAAGTGGCAGCCTGGCATGCCCCCCAACC CGTTGCCCCCGCCGTCCATCGTCAGCATGGCAGACATGCTATACAAGACGACGACGACTATGTGGAGCGAGGACA GTGAAAGGCGAGTGATTGAGCGCTTTCTCCCTTCTTTCTCTTGCATGATGAGACGTTATCGTTATACCCAGCTCA CTCAGACGCGAAACGCGGTTGCTGAGAAAACGTGATTTATCTAACTCCTGACTTTGCTTGCTTCGTTGACCTTCC ATTGCCGCCTCGTGCCTTTTGACATAACCGACGCAATGCTGACGGATTTGCTATTCACAGGTCGGTCGTTACAGA CATCAATCGCAACGTCGCCGCCACACTGAGAGCCTGTGGTCCGGCTGTGCTGGCTGGAGGCCAGGAAATGCTATC AGAGGTGGTTTCTGTCGTCGGCAGCATCATCACCCGGTCGCATCCCTGCCAGCAAGACTTGGGAGAGGAAGAAGA GGAGCGTGATATCGACGGCGGATCGTCGGAATATGACTGGCTCGTCATCGATACCGCCATGGACGTGGTCATTGG TCTCGCCGCGGCTCTGGGCGCTTCATTTGGCGAGCTGTGGAAGATCTTTGACAAGCCCATCCTGAAGCTGGTCAG CTCTTCCGAGGAGCTGCACCGGTCCACGGCCGTCGGCACCATTGCCGAGGTGACCAAGTTTGCGGGCGAGGGCAT CTCGCCCTATACCGAGTCGCTGGGCCAAGCATTGGGCCGTCGTCTTACGGACCCCGACCCTCTTACCAAGTCGAA CGCGGCCTACGCCATGGGCCTCTTGGTCTTAAAGTCGAACGAGACCAGCAAGACTGTGCCCCTCTTCCCGCAGCT CTGGGAGAAGCTGGAGCCGCTGCTGACGACAAAGGAGGTGCGCACGACGGACAACGTCGCTGGCTGCCTTGCGCG TATGATGATGAAGCACTCGGACAAGGACTTTGTCTCTCAAGCGCTCCCTGCCGTCGTCGACGTGCTCCCCCTGAC GGAGGACTACGAAGAGAACGAGCCCATCTTCCAGTGCATATACAGCCTCTGTAAGTCTCGCCAGTTCTTTCTCGG TTTGTTGTCTCGGGCTGACAGGGCAAATGGCAGACGAGCGAGGCAACGATACGGTCGAGCGACTGACGCCGCAGC TGATTGGCATCTTCGAAAAGGTCTTGAGTCCGCCCGAGGAGCAGCTGGAAGCGGAGACGCGCGAGGTGCTGCGTA CGACGGTGCAGACCATCTACAAGGCGAAGCCGGAGCTGCTGTCGGCTCATCCGGGGCTGCTGCAGCTGATGGGTG CTCACTAG |