Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophun1|2006
Gene name
Location	Contig_192:11208..14950
Strand	+
Gene length (bp)	3742
Transcript length (bp)	3672
Coding sequence length (bp)	3672
Protein length (aa)	1224

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF07989	Cnn_1N	Centrosomin N-terminal motif 1	5.6E-27	179	250
PF10495	PACT_coil_coil	Pericentrin-AKAP-450 domain of centrosomal targeting protein	3.3E-22	1116	1202

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|O94488|MBO1_SCHPO	Microtubule organizer protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mbo1 PE=1 SV=1	113	248	6.0E-09
sp|O60039|APSB_EMENI	Anucleate primary sterigmata protein B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=apsB PE=4 SV=2	178	252	6.0E-08
sp|Q8K389|CK5P2_MOUSE	CDK5 regulatory subunit-associated protein 2 OS=Mus musculus GN=Cdk5rap2 PE=1 SV=3	125	253	8.0E-07
sp|Q19UN5|CK5P2_PANTR	CDK5 regulatory subunit-associated protein 2 OS=Pan troglodytes GN=CDK5RAP2 PE=2 SV=1	140	253	6.0E-06

GO

GO Term	Description	Terminal node
GO:0005815	microtubule organizing center	Yes
GO:0110165	cellular anatomical entity	No
GO:0005575	cellular_component	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 18	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophun1|2006 MVQPGFGGALDTPRTVADVTFLSRPPDLADVSQEATFQSPARDGNNLLHQMGAGRRGIDFRTPRKQRAQPLADRR NLPLSVGGAEFTPLLKSATRNSARRLGKENAVVTVGSPALERIDEVEVTPIPRGDTSVYRSQSFIDNAALPQVDS SSVASTPLAMPSRRSGKDRGPLQDGNQLSLREQENVIDRIEKENFGLKLKIHFLEDALRKAGPGYSEAALKENTE LKVDKVTMQRELHRYKKQLTSAERDLENYRQQMLELQDRAKRKQPDDSQRAQLQKLQKTLQEREADLDELQRQVD RGHHHHQTELDTLKDTVEDLEAELREKDRAITSREDELEEVREKLEEAEERTRDLQRQAVDSARQEDLDEAKETI RRLELDKRRLEEKAGDNEVKLETAVAQRDRAEQELQTLREGLADKSMVSKNLSRQLQDRIDRLQEELDRSGDEYA GLEKELARANNENGELRASLTALRQDRQSDSVRVEELEAELLAVGDERDELQVRFDAAEEDCGALRLEAERLEKK VQKLEAKLAQEREKALQAERDLRNQFEGEMARLNDDISDLQAQVREKDNLYDNDSDKWETQRRTLESERDRAADK AAGLQRTIDRLRQAEGSLTDKESKLKAAMESESERHRSETAMLNRQMDDVKGALEARQALLTSLRGELSSVREEL RQTQIDYQTQVNKVVALEDEVEVLQTGSHDSEATRREIDKLRAQLSEIQRQQRKISPMPATESTAHLTSQLSEAT RQLERASKDKQRLQEQVAALDADVITARTSQAEAEAERDELEQQLTRAKAHDHDSNERLGLRTAKAKLDGEVRRL KEENKSLASQHAALEMSLEHELDKAAAAEDALREQISQLQAQLRQSSSSETHELAAARRSVRELERRVADYQMQL AAGQGDDGNDDVNGGRDSSQLSIIRKDLSASRQKELDLLQRESTHRDQIRSLKRQITDLEQRLHEKQVSHLVTHN HHHHQEEDSHQQDLLQRLTDAQDQRQVLEELLDEARATAAQHQQDLDHNRLQQHRLAEDAQLQESIVQRLVEHEA VLRRKLERARSERAAYRLSAEKLQRDVRLLRDSPASSPAPDGDDAHVVANKERRGLVLQMQWMQARWEREAVLRS DAAFAKTFLQLELNVAQACNKAQLRELDDIRARFRSSKPLPLPLPVNPRRPSPQMRLRATLHAVRFVARVRIAAR EWGRQEVLRLRLVDAYREDRRRR*
Coding	>Ophun1|2006 ATGGTCCAGCCAGGGTTTGGCGGTGCGCTCGACACGCCGCGGACCGTCGCCGACGTGACCTTTCTCAGCCGTCCG CCAGACCTGGCTGATGTCTCCCAGGAGGCAACCTTTCAGTCTCCCGCCCGCGATGGCAACAACCTGCTTCACCAG ATGGGCGCCGGCCGCCGCGGCATCGACTTCCGGACACCTCGCAAACAGCGAGCTCAGCCGCTGGCCGACCGGCGG AACCTACCGCTCAGCGTCGGAGGCGCCGAGTTCACGCCCCTGCTCAAATCGGCGACGAGGAACAGCGCACGCCGG CTCGGTAAGGAGAATGCCGTCGTCACCGTTGGCTCGCCGGCCCTCGAGCGTATCGACGAGGTCGAAGTGACGCCT ATTCCCCGGGGGGACACGTCCGTATACCGCAGCCAGTCCTTCATCGACAACGCGGCACTGCCTCAGGTGGACAGC AGCAGCGTTGCCTCGACTCCTCTTGCGATGCCGTCGCGTCGGAGCGGCAAGGATAGGGGTCCTCTGCAAGACGGG AACCAGCTGTCGTTACGCGAACAGGAAAACGTCATCGATCGGATAGAAAAGGAAAATTTCGGTCTCAAGCTCAAG ATACACTTCCTCGAGGATGCCCTGCGCAAGGCTGGTCCTGGATACAGCGAGGCGGCTCTCAAGGAGAACACGGAG CTCAAGGTGGACAAGGTGACGATGCAGAGGGAGCTTCACCGCTACAAGAAGCAACTCACGTCGGCCGAGCGCGAT CTCGAAAACTACCGTCAGCAGATGCTCGAGCTCCAAGACAGGGCCAAGCGCAAGCAGCCGGACGATTCCCAGCGC GCCCAACTACAGAAGCTGCAGAAGACACTGCAAGAGCGCGAGGCTGACCTTGACGAGCTGCAGCGCCAGGTCGAC AGGGGCCACCATCATCACCAGACGGAGCTCGACACACTCAAGGATACCGTCGAGGATCTCGAGGCCGAGCTCAGA GAAAAGGATCGGGCCATCACCAGCCGCGAGGACGAGCTCGAAGAAGTCCGAGAGAAGCTGGAGGAAGCCGAGGAG AGGACTAGGGACTTGCAGCGACAGGCCGTCGACAGCGCTCGCCAGGAGGATCTCGATGAGGCCAAGGAGACGATT CGACGCCTCGAACTGGACAAGCGCCGACTCGAGGAAAAGGCTGGCGACAACGAGGTCAAGCTCGAGACAGCCGTG GCTCAGAGAGACCGAGCCGAACAGGAGCTGCAGACGCTGCGAGAAGGTCTGGCCGACAAGTCCATGGTCAGCAAG AACCTGTCGCGCCAGCTCCAAGATCGAATCGATCGGCTGCAGGAAGAGCTGGACCGGAGCGGCGACGAGTACGCC GGCCTAGAGAAGGAGCTCGCTCGTGCCAACAACGAGAACGGCGAGCTCCGAGCCAGCCTGACGGCGCTCCGACAA GACAGGCAATCCGACTCGGTCCGGGTGGAGGAGCTCGAGGCCGAGTTACTGGCCGTGGGCGACGAGAGGGACGAG CTGCAGGTGCGCTTCGATGCTGCCGAAGAGGACTGCGGCGCGCTCCGTCTCGAGGCCGAGCGGTTGGAGAAGAAG GTGCAGAAGCTGGAGGCGAAGCTGGCTCAGGAGCGGGAGAAGGCACTTCAGGCGGAGAGAGACTTGCGGAACCAG TTCGAGGGCGAGATGGCGCGTCTCAACGATGACATCTCGGACCTTCAAGCCCAAGTTCGAGAAAAGGACAATCTG TACGACAACGACAGCGACAAGTGGGAGACGCAACGGCGGACGCTCGAGTCGGAACGGGACCGAGCCGCAGACAAG GCAGCCGGTCTTCAGCGGACCATCGACCGGCTACGCCAGGCCGAGGGCAGCCTGACGGACAAGGAGTCGAAGCTC AAGGCGGCCATGGAGAGCGAGAGCGAACGGCACCGCAGCGAGACAGCCATGCTGAACCGACAGATGGACGACGTC AAAGGTGCGCTCGAGGCGCGACAAGCGCTGCTGACCAGCCTCCGCGGCGAGCTATCGTCGGTGCGTGAGGAGTTG CGGCAGACGCAGATCGACTATCAGACGCAGGTCAACAAGGTCGTCGCCCTGGAAGACGAAGTCGAGGTGCTGCAG ACGGGCAGCCATGATTCCGAAGCGACCCGACGCGAGATCGACAAGCTCCGCGCCCAGCTGAGCGAGATCCAGCGA CAGCAGAGAAAGATCAGTCCCATGCCAGCCACCGAGTCGACAGCCCACTTGACGAGCCAGCTATCCGAAGCAACC CGCCAGCTGGAGAGGGCCTCCAAGGACAAGCAGAGGCTACAAGAGCAGGTAGCAGCTCTCGACGCAGACGTCATC ACGGCGCGCACCTCGCAAGCCGAAGCCGAGGCCGAAAGAGACGAGCTCGAGCAGCAGCTCACGCGGGCCAAGGCG CACGACCACGACAGCAACGAGCGATTGGGCCTCCGTACCGCAAAGGCCAAGCTCGACGGCGAGGTCCGAAGGCTC AAGGAGGAGAACAAGAGTCTGGCGTCGCAACACGCCGCTCTCGAGATGTCGCTTGAGCACGAGCTCGACAAGGCG GCCGCAGCAGAGGACGCGTTGCGCGAGCAAATCTCCCAGCTACAGGCCCAGCTGCGACAGTCATCTTCGTCCGAG ACGCACGAGTTGGCGGCGGCGCGTCGCTCGGTTCGCGAACTGGAGCGGCGCGTGGCGGATTATCAGATGCAACTC GCTGCTGGTCAAGGTGACGATGGCAACGATGACGTCAACGGCGGTCGCGATAGCAGCCAGCTATCTATCATCCGA AAAGACCTCTCAGCCTCGCGACAGAAGGAACTCGACCTCCTGCAACGCGAATCAACCCACCGCGACCAAATCAGA AGCCTCAAAAGGCAAATCACCGATCTCGAACAGCGCCTCCACGAAAAACAAGTCTCCCACCTCGTCACCCACAAC CACCACCACCACCAAGAAGAAGACTCCCATCAACAAGACCTCCTCCAACGCCTAACCGACGCCCAAGACCAGCGC CAAGTCCTAGAAGAACTCCTCGACGAAGCCCGCGCAACCGCCGCCCAACACCAACAAGACCTCGACCACAACCGC CTCCAGCAACATCGCCTCGCCGAGGACGCCCAGCTGCAGGAGAGCATCGTTCAGCGTCTGGTGGAGCATGAGGCT GTGCTGAGGAGGAAGCTTGAGCGCGCTCGCAGCGAGAGGGCTGCCTATCGCTTGAGTGCTGAGAAGCTTCAGCGT GATGTTCGACTGCTCCGCGACTCTCCAGCTTCTTCCCCGGCTCCGGATGGCGATGACGCTCATGTCGTGGCCAAC AAGGAGAGACGAGGCCTCGTCCTGCAAATGCAATGGATGCAGGCCCGCTGGGAGAGAGAAGCCGTCTTAAGATCC GACGCCGCCTTCGCAAAGACCTTCCTGCAACTCGAGCTCAACGTCGCCCAAGCCTGCAACAAGGCCCAACTCCGC GAACTCGACGACATCCGCGCCCGCTTCCGCTCCAGCAAGCCCCTTCCCCTCCCCCTCCCCGTCAACCCCCGCCGT CCTTCTCCGCAGATGCGCCTCCGAGCCACGCTCCACGCCGTCCGCTTCGTCGCCCGCGTCCGCATCGCCGCCCGC GAATGGGGCCGTCAAGAGGTTCTTCGTCTTCGCCTCGTCGACGCCTACCGCGAGGATAGGCGCCGTCGATGA
Transcript	>Ophun1|2006 ATGGTCCAGCCAGGGTTTGGCGGTGCGCTCGACACGCCGCGGACCGTCGCCGACGTGACCTTTCTCAGCCGTCCG CCAGACCTGGCTGATGTCTCCCAGGAGGCAACCTTTCAGTCTCCCGCCCGCGATGGCAACAACCTGCTTCACCAG ATGGGCGCCGGCCGCCGCGGCATCGACTTCCGGACACCTCGCAAACAGCGAGCTCAGCCGCTGGCCGACCGGCGG AACCTACCGCTCAGCGTCGGAGGCGCCGAGTTCACGCCCCTGCTCAAATCGGCGACGAGGAACAGCGCACGCCGG CTCGGTAAGGAGAATGCCGTCGTCACCGTTGGCTCGCCGGCCCTCGAGCGTATCGACGAGGTCGAAGTGACGCCT ATTCCCCGGGGGGACACGTCCGTATACCGCAGCCAGTCCTTCATCGACAACGCGGCACTGCCTCAGGTGGACAGC AGCAGCGTTGCCTCGACTCCTCTTGCGATGCCGTCGCGTCGGAGCGGCAAGGATAGGGGTCCTCTGCAAGACGGG AACCAGCTGTCGTTACGCGAACAGGAAAACGTCATCGATCGGATAGAAAAGGAAAATTTCGGTCTCAAGCTCAAG ATACACTTCCTCGAGGATGCCCTGCGCAAGGCTGGTCCTGGATACAGCGAGGCGGCTCTCAAGGAGAACACGGAG CTCAAGGTGGACAAGGTGACGATGCAGAGGGAGCTTCACCGCTACAAGAAGCAACTCACGTCGGCCGAGCGCGAT CTCGAAAACTACCGTCAGCAGATGCTCGAGCTCCAAGACAGGGCCAAGCGCAAGCAGCCGGACGATTCCCAGCGC GCCCAACTACAGAAGCTGCAGAAGACACTGCAAGAGCGCGAGGCTGACCTTGACGAGCTGCAGCGCCAGGTCGAC AGGGGCCACCATCATCACCAGACGGAGCTCGACACACTCAAGGATACCGTCGAGGATCTCGAGGCCGAGCTCAGA GAAAAGGATCGGGCCATCACCAGCCGCGAGGACGAGCTCGAAGAAGTCCGAGAGAAGCTGGAGGAAGCCGAGGAG AGGACTAGGGACTTGCAGCGACAGGCCGTCGACAGCGCTCGCCAGGAGGATCTCGATGAGGCCAAGGAGACGATT CGACGCCTCGAACTGGACAAGCGCCGACTCGAGGAAAAGGCTGGCGACAACGAGGTCAAGCTCGAGACAGCCGTG GCTCAGAGAGACCGAGCCGAACAGGAGCTGCAGACGCTGCGAGAAGGTCTGGCCGACAAGTCCATGGTCAGCAAG AACCTGTCGCGCCAGCTCCAAGATCGAATCGATCGGCTGCAGGAAGAGCTGGACCGGAGCGGCGACGAGTACGCC GGCCTAGAGAAGGAGCTCGCTCGTGCCAACAACGAGAACGGCGAGCTCCGAGCCAGCCTGACGGCGCTCCGACAA GACAGGCAATCCGACTCGGTCCGGGTGGAGGAGCTCGAGGCCGAGTTACTGGCCGTGGGCGACGAGAGGGACGAG CTGCAGGTGCGCTTCGATGCTGCCGAAGAGGACTGCGGCGCGCTCCGTCTCGAGGCCGAGCGGTTGGAGAAGAAG GTGCAGAAGCTGGAGGCGAAGCTGGCTCAGGAGCGGGAGAAGGCACTTCAGGCGGAGAGAGACTTGCGGAACCAG TTCGAGGGCGAGATGGCGCGTCTCAACGATGACATCTCGGACCTTCAAGCCCAAGTTCGAGAAAAGGACAATCTG TACGACAACGACAGCGACAAGTGGGAGACGCAACGGCGGACGCTCGAGTCGGAACGGGACCGAGCCGCAGACAAG GCAGCCGGTCTTCAGCGGACCATCGACCGGCTACGCCAGGCCGAGGGCAGCCTGACGGACAAGGAGTCGAAGCTC AAGGCGGCCATGGAGAGCGAGAGCGAACGGCACCGCAGCGAGACAGCCATGCTGAACCGACAGATGGACGACGTC AAAGGTGCGCTCGAGGCGCGACAAGCGCTGCTGACCAGCCTCCGCGGCGAGCTATCGTCGGTGCGTGAGGAGTTG CGGCAGACGCAGATCGACTATCAGACGCAGGTCAACAAGGTCGTCGCCCTGGAAGACGAAGTCGAGGTGCTGCAG ACGGGCAGCCATGATTCCGAAGCGACCCGACGCGAGATCGACAAGCTCCGCGCCCAGCTGAGCGAGATCCAGCGA CAGCAGAGAAAGATCAGTCCCATGCCAGCCACCGAGTCGACAGCCCACTTGACGAGCCAGCTATCCGAAGCAACC CGCCAGCTGGAGAGGGCCTCCAAGGACAAGCAGAGGCTACAAGAGCAGGTAGCAGCTCTCGACGCAGACGTCATC ACGGCGCGCACCTCGCAAGCCGAAGCCGAGGCCGAAAGAGACGAGCTCGAGCAGCAGCTCACGCGGGCCAAGGCG CACGACCACGACAGCAACGAGCGATTGGGCCTCCGTACCGCAAAGGCCAAGCTCGACGGCGAGGTCCGAAGGCTC AAGGAGGAGAACAAGAGTCTGGCGTCGCAACACGCCGCTCTCGAGATGTCGCTTGAGCACGAGCTCGACAAGGCG GCCGCAGCAGAGGACGCGTTGCGCGAGCAAATCTCCCAGCTACAGGCCCAGCTGCGACAGTCATCTTCGTCCGAG ACGCACGAGTTGGCGGCGGCGCGTCGCTCGGTTCGCGAACTGGAGCGGCGCGTGGCGGATTATCAGATGCAACTC GCTGCTGGTCAAGGTGACGATGGCAACGATGACGTCAACGGCGGTCGCGATAGCAGCCAGCTATCTATCATCCGA AAAGACCTCTCAGCCTCGCGACAGAAGGAACTCGACCTCCTGCAACGCGAATCAACCCACCGCGACCAAATCAGA AGCCTCAAAAGGCAAATCACCGATCTCGAACAGCGCCTCCACGAAAAACAAGTCTCCCACCTCGTCACCCACAAC CACCACCACCACCAAGAAGAAGACTCCCATCAACAAGACCTCCTCCAACGCCTAACCGACGCCCAAGACCAGCGC CAAGTCCTAGAAGAACTCCTCGACGAAGCCCGCGCAACCGCCGCCCAACACCAACAAGACCTCGACCACAACCGC CTCCAGCAACATCGCCTCGCCGAGGACGCCCAGCTGCAGGAGAGCATCGTTCAGCGTCTGGTGGAGCATGAGGCT GTGCTGAGGAGGAAGCTTGAGCGCGCTCGCAGCGAGAGGGCTGCCTATCGCTTGAGTGCTGAGAAGCTTCAGCGT GATGTTCGACTGCTCCGCGACTCTCCAGCTTCTTCCCCGGCTCCGGATGGCGATGACGCTCATGTCGTGGCCAAC AAGGAGAGACGAGGCCTCGTCCTGCAAATGCAATGGATGCAGGCCCGCTGGGAGAGAGAAGCCGTCTTAAGATCC GACGCCGCCTTCGCAAAGACCTTCCTGCAACTCGAGCTCAACGTCGCCCAAGCCTGCAACAAGGCCCAACTCCGC GAACTCGACGACATCCGCGCCCGCTTCCGCTCCAGCAAGCCCCTTCCCCTCCCCCTCCCCGTCAACCCCCGCCGT CCTTCTCCGCAGATGCGCCTCCGAGCCACGCTCCACGCCGTCCGCTTCGTCGCCCGCGTCCGCATCGCCGCCCGC GAATGGGGCCGTCAAGAGGTTCTTCGTCTTCGCCTCGTCGACGCCTACCGCGAGGATAGGCGCCGTCGATGA
Gene	>Ophun1|2006 ATGGTCCAGCCAGGGTTTGGCGGTGCGCTCGACACGCCGCGGACCGTCGCCGACGTGACCTTTCTCAGCCGTCCG CCAGACCTGGCTGATGTCTCCCAGGAGGCAACCTTTCAGTCTCCCGCCCGCGATGGCAACAACCTGCTTCACCAG ATGGGCGCCGGCCGCCGCGGCATCGACTTCCGGACACCTCGCAAACAGCGAGCTCAGCCGCTGGCCGACCGGCGG AACCTACCGCTCAGCGTCGGAGGCGCCGAGTTCACGCCCCTGCTCAAATCGGCGACGAGGAACAGCGCACGCCGG CTCGGTAAGGAGAATGCCGTCGTCACCGTTGGCTCGCCGGCCCTCGAGCGTATCGACGAGGTCGAAGTGACGCCT ATTCCCCGGGGGGACACGTCCGTATACCGCAGCCAGTCCTTCATCGACAACGCGGCACTGCCTCAGGTGGACAGC AGCAGCGTTGCCTCGACTCCTCTTGCGATGCCGTCGCGTCGGAGCGGCAAGGATAGGGGTCCTCTGCAAGACGGG AACCAGCTGTCGTTACGCGAACAGGAAAACGTCATCGATCGGATAGAAAAGGAAAATTTCGGTCTCAAGCTCAAG ATACACTTCCTCGAGGATGCCCTGCGCAAGGCTGGTCCTGGATACAGCGAGGCGGCTCTCAAGGAGAACACGGAG CTCAAGGTGGACAAGGTGACGATGCAGAGGGAGCTTCACCGCTACAAGAAGCAACTCACGTCGGCCGAGCGCGAT CTCGAAAACTACCGTCAGCAGATGCTCGAGCTCCAAGACAGGGCCAAGCGCAAGCAGCCGGACGATTCCCAGCGC GCCCAACTACAGAAGCTGCAGAAGACACTGCAAGAGCGCGAGGCTGACCTTGACGAGCTGCAGCGCCAGGTCGAC AGGGGCCACCATCATCACCAGACGGAGCTCGACACACTCAAGGATACCGTCGAGGATCTCGAGGCCGAGCTCAGA GAAAAGGATCGGGCCATCACCAGCCGCGAGGACGAGCTCGAAGAAGTCCGAGAGAAGCTGGAGGAAGCCGAGGAG AGGACTAGGGACTTGCAGCGACAGGCCGTCGACAGCGCTCGCCAGGAGGATCTCGATGAGGCCAAGGAGACGATT CGACGCCTCGAACTGGACAAGCGCCGACTCGAGGAAAAGGCTGGCGACAACGAGGTCAAGCTCGAGACAGCCGTG GCTCAGAGAGACCGAGCCGAACAGGAGCTGCAGACGCTGCGAGAAGGTCTGGCCGACAAGTCCATGGTCAGCAAG AACCTGTCGCGCCAGCTCCAAGATCGAATCGATCGGCTGCAGGAAGAGCTGGACCGGAGCGGCGACGAGTACGCC GGCCTAGAGAAGGAGCTCGCTCGTGCCAACAACGAGAACGGCGAGCTCCGAGCCAGCCTGACGGCGCTCCGACAA GACAGGCAATCCGACTCGGTCCGGGTGGAGGAGCTCGAGGCCGAGTTACTGGCCGTGGGCGACGAGAGGGACGAG CTGCAGGTGCGCTTCGATGCTGCCGAAGAGGACTGCGGCGCGCTCCGTCTCGAGGCCGAGCGGTTGGAGAAGAAG GTGCAGAAGCTGGAGGCGAAGCTGGCTCAGGAGCGGGAGAAGGCACTTCAGGCGGAGAGAGACTTGCGGAACCAG TTCGAGGGCGAGATGGCGCGTCTCAACGATGACATCTCGGACCTTCAAGCCCAAGTTCGAGAAAAGGACAATCTG TACGACAACGACAGCGACAAGTGGGAGACGCAACGGCGGACGCTCGAGTCGGAACGGGACCGAGCCGCAGACAAG GCAGCCGGTCTTCAGCGGACCATCGACCGGCTACGCCAGGCCGAGGGCAGCCTGACGGACAAGGAGTCGAAGCTC AAGGCGGCCATGGAGAGCGAGAGCGAACGGCACCGCAGCGAGACAGCCATGCTGAACCGACAGATGGACGACGTC AAAGGTGCGCTCGAGGCGCGACAAGCGCTGCTGACCAGCCTCCGCGGCGAGCTATCGTCGGTGCGTGAGGAGTTG CGGCAGACGCAGATCGACTATCAGACGCAGGTCAACAAGGTCGTCGCCCTGGAAGACGAAGTCGAGGTGCTGCAG ACGGGCAGCCATGATTCCGAAGCGACCCGACGCGAGATCGACAAGCTCCGCGCCCAGCTGAGCGAGATCCAGCGA CAGCAGAGAAAGATCAGTCCCATGCCAGCCACCGAGTCGACAGCCCACTTGACGAGCCAGCTATCCGAAGCAACC CGCCAGCTGGAGAGGGCCTCCAAGGACAAGCAGAGGCTACAAGAGCAGGTAGCAGCTCTCGACGCAGACGTCATC ACGGCGCGCACCTCGCAAGCCGAAGCCGAGGCCGAAAGAGACGAGCTCGAGCAGCAGCTCACGCGGGCCAAGGCG CACGACCACGACAGCAACGAGCGATTGGGCCTCCGTACCGCAAAGGCCAAGCTCGACGGCGAGGTCCGAAGGCTC AAGGAGGAGAACAAGAGTCTGGCGTCGCAACACGCCGCTCTCGAGATGTCGCTTGAGCACGAGCTCGACAAGGCG GCCGCAGCAGAGGACGCGTTGCGCGAGCAAATCTCCCAGCTACAGGCCCAGCTGCGACAGTCATCTTCGTCCGAG ACGCACGAGTTGGCGGCGGCGCGTCGCTCGGTTCGCGAACTGGAGCGGCGCGTGGCGGATTATCAGATGCAACTC GCTGCTGGTCAAGGTGACGATGGCAACGATGACGTCAACGGCGGTCGCGATAGCAGCCAGCTATCTATCATCCGA AAAGACCTCTCAGCCTCGCGACAGAAGGAACTCGACCTCCTGCAACGCGAATCAACCCACCGCGACCAAATCAGA AGCCTCAAAAGGCAAATCACCGATCTCGAACAGCGCCTCCACGAAAAACAAGTCTCCCACCTCGTCACCCACAAC CACCACCACCACCAAGAAGAAGACTCCCATCAACAAGACCTCCTCCAACGCCTAACCGACGCCCAAGACCAGCGC CAAGTCCTAGAAGAACTCCTCGACGAAGCCCGCGCAACCGCCGCCCAACACCAACAAGACCTCGACCACAACCGC CTCCAGCAACATCGCCTCGCCGAGGACGCCCAGCTGCAGGAGAGCATCGTTCAGCGTCTGGTGGAGCATGAGGCT GTGCTGAGGAGGAAGCTTGAGCGCGCTCGCAGCGAGAGGGCTGCCTATCGCTTGAGTGCTGAGAAGCTTCAGCGT GATGTTCGACTGCTCCGCGACTCTCCAGCTTCTTCCCCGGCTCCGGATGGCGATGACGCTCATGTCGTGGCCAAC AAGGAGAGACGAGGCCTCGTCCTGCAAATGCAATGGATGCAGGCCCGCTGGGAGAGAGAAGCCGTCTTAAGATCC GACGCCGCCTTCGCAAAGACCTTCCTGCAACTCGAGCTCAACGTCGCCCAAGCCTGGTTAGTCTCCCCCCCCCCT ATTCTTCTATCTTCCCCCCTCCCCCCCTTTTCACCTCTAACTCTTCACCAGCAACAAGGCCCAACTCCGCGAACT CGACGACATCCGCGCCCGCTTCCGCTCCAGCAAGCCCCTTCCCCTCCCCCTCCCCGTCAACCCCCGCCGTCCTTC TCCGCAGATGCGCCTCCGAGCCACGCTCCACGCCGTCCGCTTCGTCGCCCGCGTCCGCATCGCCGCCCGCGAATG GGGCCGTCAAGAGGTTCTTCGTCTTCGCCTCGTCGACGCCTACCGCGAGGATAGGCGCCGTCGATGA