Fungal Genomics

at Utrecht University

General Properties

Protein ID	Ophun1\|199
Gene name
Location	Contig_1036:423..4588
Strand	+
Gene length (bp)	4165
Transcript length (bp)	3594
Coding sequence length (bp)	3594
Protein length (aa)	1198

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF02537	CRCB	CrcB-like protein, Camphor Resistance (CrcB)	3.0E-19	102	204
PF14737	DUF4470	Domain of unknown function (DUF4470)	3.6E-14	326	422
PF01753	zf-MYND	MYND finger	3.6E-05	261	295

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9UTS8\|YI7B_SCHPO	UPF0695 membrane protein C977.11/PB8B6.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC977.11 PE=3 SV=1	21	212	3.0E-12
sp\|Q3SK07\|CRCB_THIDA	Putative fluoride ion transporter CrcB OS=Thiobacillus denitrificans (strain ATCC 25259) GN=crcB PE=3 SV=1	108	185	3.0E-07
sp\|Q08913\|YO390_YEAST	UPF0695 membrane protein YOR390W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YOR390W PE=3 SV=1	63	184	8.0E-07
sp\|Q08991\|YP279_YEAST	UPF0695 membrane protein YPL279C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPL279C PE=3 SV=1	63	184	1.0E-06
sp\|Q93TE2\|CRCB_PSEYM	Putative fluoride ion transporter CrcB OS=Pseudomonas syringae pv. maculicola GN=crcB PE=3 SV=1	99	190	1.0E-06

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9UTS8\|YI7B_SCHPO	UPF0695 membrane protein C977.11/PB8B6.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC977.11 PE=3 SV=1	21	212	3.0E-12
sp\|Q3SK07\|CRCB_THIDA	Putative fluoride ion transporter CrcB OS=Thiobacillus denitrificans (strain ATCC 25259) GN=crcB PE=3 SV=1	108	185	3.0E-07
sp\|Q08913\|YO390_YEAST	UPF0695 membrane protein YOR390W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YOR390W PE=3 SV=1	63	184	8.0E-07
sp\|Q08991\|YP279_YEAST	UPF0695 membrane protein YPL279C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPL279C PE=3 SV=1	63	184	1.0E-06
sp\|Q93TE2\|CRCB_PSEYM	Putative fluoride ion transporter CrcB OS=Pseudomonas syringae pv. maculicola GN=crcB PE=3 SV=1	99	190	1.0E-06
sp\|Q9FC37\|CRCB2_STRCO	Putative fluoride ion transporter CrcB 2 OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) GN=crcB2 PE=3 SV=1	129	207	1.0E-06
sp\|B4EBU8\|CRCB_BURCJ	Putative fluoride ion transporter CrcB OS=Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) GN=crcB PE=3 SV=1	101	185	4.0E-06

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GO

GO Term	Description	Terminal node
GO:0016021	integral component of membrane	Yes
GO:0110165	cellular anatomical entity	No
GO:0031224	intrinsic component of membrane	No
GO:0005575	cellular_component	No

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 55	0.5

Transmembrane Domains

Domain #	Start	End	Length
1	27	49	22
2	76	95	19
3	100	122	22
4	129	148	19
5	163	185	22
6	198	217	19

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophun1\|199 MTDDLYWPVTAEVRIPGQGGRSSGRDFMALVAVVIVTVSLSLSGLFIGAHLALATERIPPSLPQPATRRFIDPAG VFLGWGGWLASILLCALLPHRSWRGILFALVFAPLGTLLRFRLALWLNGARPSFPLGTFTANMVGTAVLGMAWDL EHVPIGGVVGCQVLMGVGDGFCGCLTTVSTWVAELSGLGQSRPASHTLGASLAIIIVIPVIMIIEYTDRTPAPAS VPSIMITPPITDLTKPLRAMPRPICAAETEHKGELCGAEPRLICPYCYIFAYCSSSCRRRHWKESHHKECQKAID MALPDGWTVDNPVALGDWLSSQKTYWHNYPATDVLRLDKTEGAWFESSLNMLFYGAAGIRHLIYSVANMVDTARP QLNVVVDEHHFSHYLRSFLALHLLAANGFDPVDNAEAVIHMWYSSLLPRRIHDHIRAVVRANTDGFFDSKKELKK GKLSLLTWGTGHQLFEAAMTQRDFDVICDFFDDTSTQIRLDEACRFVDRNKDIEPVEGLLARMDRSRCLSLLKWR EDGLFLPYTYSRHEFDMLNPIIYSKNWPFQKGVSSEPLTEWPMEILDFDCGPATEDMYGKAYFYLHDLFVRFQGR LADMSVRIRVAGRAIVDIDPRLYFLPWGDLHDRIEVGETWDTAPLTATVFASRFLRPTQHNPFATALMMTKESLN RPCVVTETEAAQENAKLLKKTGLALDQLAPPVKNVTDDPKMTARRALALVLWRDWDKFSDAFLESPTHFGFNSIS FSTSESKSAILVDESIIRLKPKLKSKPNPNPRSIVEEGFLGLHMQRQNTITQRFPNRVVHKAADVPCVDEFERWM SWASVKPQRWLEWKRVGDEADCDFDEWMLWVSLTVKHLADEIELILAQSLLEDPIDRVWMSKVGSTGETTLWGPR ETGTSEKLEGRFWDEVRAGVARGDIKWVPIVRVDCDYGDGGLDQIKKDEKGKGKAGEEESSGGSDGDLEEGEMVE VDEQGELSFASQLGKGKAKEVDIGKPLEIKKSVETSNPFEDPPPGYTEMNEQTRALEPESSRPAEEDTVQTSKPK KKKKNKKKKKKKSKGKGQASGQPADEHSDFTSANTDDSDAMDADTETLSGDELVRFLMQKLEKGMADTEERIMEA EKGNRLSLHMVGQIKALRTKDRNADDWGLKAMEAEMTRMRDVANRQLVASRQKMQRIGDSLKRLCGVDGGAL*
Coding	>Ophun1\|199 ATGACGGATGATCTCTACTGGCCTGTCACTGCCGAGGTGCGTATCCCTGGTCAAGGCGGTCGGAGCAGCGGACGG GATTTTATGGCGCTGGTGGCTGTTGTCATCGTCACCGTTTCTCTCTCACTGTCTGGTCTATTCATCGGTGCGCAT CTGGCTTTGGCGACGGAGAGGATTCCACCATCGTTACCTCAGCCGGCGACGAGGCGCTTCATCGACCCAGCTGGC GTCTTCCTCGGTTGGGGAGGCTGGCTAGCATCCATCCTCCTCTGCGCCCTCCTCCCCCACCGCTCATGGCGAGGC ATCCTCTTCGCCCTCGTCTTCGCGCCTCTAGGAACCCTCCTACGCTTCCGCCTAGCCCTCTGGCTCAACGGAGCC CGTCCATCCTTCCCGCTCGGCACCTTCACGGCTAACATGGTGGGTACGGCGGTGCTGGGCATGGCGTGGGATCTC GAGCACGTGCCCATCGGGGGCGTTGTCGGATGTCAGGTGCTGATGGGCGTTGGCGATGGTTTCTGCGGCTGCTTG ACGACGGTTTCGACTTGGGTTGCTGAGTTGAGTGGTCTCGGCCAGTCTCGGCCAGCATCTCATACTCTCGGCGCC TCACTGGCCATCATCATCGTCATCCCAGTCATCATGATCATAGAATACACCGATAGGACACCGGCGCCGGCGTCG GTGCCATCCATCATGATTACCCCCCCGATCACGGACTTGACGAAACCGCTCAGGGCCATGCCTCGTCCGATATGC GCCGCCGAAACAGAACACAAGGGGGAACTCTGCGGCGCCGAGCCTCGCCTCATATGCCCCTACTGCTACATCTTT GCGTACTGCTCTTCTAGCTGCAGACGGCGTCACTGGAAGGAGTCCCATCATAAGGAGTGCCAGAAGGCCATCGAC ATGGCGCTGCCGGATGGATGGACCGTCGACAATCCTGTTGCCTTGGGCGACTGGCTCTCTTCGCAAAAGACGTAT TGGCACAACTATCCGGCCACCGACGTTCTGCGGCTGGATAAAACAGAGGGCGCGTGGTTCGAGTCTAGCCTCAAC ATGCTCTTCTATGGGGCTGCGGGCATACGCCATCTGATCTACAGCGTCGCCAACATGGTCGATACAGCCAGGCCT CAGCTGAATGTCGTCGTCGACGAGCACCATTTCTCTCATTATCTACGCTCTTTTCTGGCCCTACACCTTCTCGCG GCCAACGGCTTCGACCCTGTGGACAACGCCGAGGCCGTCATCCACATGTGGTATTCGTCACTGCTGCCCAGGCGG ATCCATGATCACATTCGAGCCGTGGTCAGGGCCAACACGGACGGCTTCTTCGACAGCAAAAAGGAGCTGAAAAAG GGGAAATTGTCGTTGCTGACTTGGGGCACTGGCCATCAGTTGTTCGAGGCGGCCATGACCCAGAGAGACTTTGAC GTTATCTGCGACTTTTTTGACGATACGTCGACTCAAATCCGTCTTGATGAAGCCTGCCGCTTCGTGGACAGGAAC AAAGACATCGAGCCTGTTGAAGGACTGCTGGCTCGGATGGATCGTTCTCGCTGTCTTAGCCTGCTCAAATGGCGT GAAGACGGCCTATTTCTGCCCTACACCTATTCTCGCCATGAGTTTGATATGCTCAACCCTATCATTTACAGCAAA AACTGGCCTTTTCAGAAAGGCGTATCGTCTGAGCCCCTGACGGAGTGGCCCATGGAGATTCTCGACTTCGACTGT GGTCCTGCCACGGAAGACATGTACGGCAAGGCCTACTTTTACCTTCACGATCTCTTTGTGCGCTTTCAAGGCAGG CTGGCCGACATGTCCGTGCGGATACGGGTGGCAGGGAGGGCCATTGTCGACATCGATCCCAGGCTGTACTTTCTG CCCTGGGGGGATCTTCACGACCGCATCGAGGTTGGCGAGACGTGGGATACGGCACCCTTGACGGCCACCGTCTTC GCGTCTCGATTCCTGCGACCGACTCAGCACAACCCATTCGCGACGGCATTGATGATGACGAAAGAGTCGTTGAAT AGGCCTTGTGTCGTTACCGAGACAGAAGCGGCGCAGGAGAACGCCAAGCTGCTCAAAAAGACGGGTCTGGCTCTC GATCAGCTGGCGCCGCCTGTCAAGAATGTCACGGATGATCCCAAAATGACGGCTCGTCGTGCCCTTGCCCTCGTG CTGTGGCGCGACTGGGACAAGTTCTCAGACGCCTTTCTCGAATCGCCTACTCACTTTGGCTTCAACTCCATATCC TTCTCGACGTCCGAGTCCAAGTCAGCCATCCTCGTCGATGAAAGCATTATCCGCCTGAAGCCGAAGCTCAAGTCG AAGCCGAATCCGAACCCGCGCAGCATCGTCGAGGAGGGCTTCCTTGGCCTGCACATGCAAAGGCAGAATACCATC ACTCAACGCTTCCCGAACCGAGTCGTCCACAAGGCTGCGGACGTGCCTTGCGTCGACGAGTTTGAACGTTGGATG AGCTGGGCGAGTGTCAAGCCTCAGCGATGGCTGGAGTGGAAGCGCGTTGGGGACGAGGCTGACTGCGACTTTGAC GAATGGATGCTTTGGGTTTCGCTTACTGTCAAGCACTTGGCGGACGAGATCGAGTTGATCCTGGCTCAGAGCTTG CTCGAAGACCCGATTGATCGTGTTTGGATGAGCAAGGTAGGGTCCACGGGCGAGACGACGCTTTGGGGTCCGAGG GAGACCGGCACGTCGGAGAAGCTTGAGGGTCGGTTCTGGGACGAGGTCAGGGCGGGGGTTGCGAGGGGGGATATC AAATGGGTGCCTATTGTCCGAGTTGACTGTGACTATGGTGATGGTGGTCTTGATCAGATCAAGAAGGACGAGAAG GGCAAGGGCAAGGCTGGGGAAGAAGAGTCGTCTGGGGGGAGTGATGGAGATTTGGAGGAGGGGGAGATGGTCGAG GTCGACGAGCAGGGAGAGCTGTCTTTTGCCAGTCAGTTGGGAAAGGGGAAGGCGAAGGAGGTTGACATCGGCAAG CCGCTCGAGATCAAAAAGTCGGTTGAGACCAGCAACCCATTCGAAGATCCGCCTCCCGGCTACACCGAAATGAAC GAGCAGACAAGGGCACTCGAGCCGGAATCCAGCAGGCCAGCCGAGGAAGACACCGTCCAGACCAGCAAGCCGAAG AAGAAGAAGAAGAACAAAAAGAAGAAGAAGAAGAAGTCCAAGGGAAAAGGCCAGGCGTCTGGTCAGCCAGCCGAC GAGCACTCGGACTTTACTTCAGCGAATACCGACGACAGTGATGCCATGGACGCGGACACAGAGACGCTGTCTGGA GACGAACTCGTCCGTTTCCTGATGCAGAAGCTGGAGAAGGGCATGGCGGATACGGAGGAGAGGATCATGGAGGCG GAGAAGGGGAACCGTCTGAGTTTGCACATGGTCGGGCAGATCAAGGCGCTGAGGACGAAGGATCGGAATGCTGAC GATTGGGGGCTGAAGGCCATGGAGGCGGAGATGACGCGGATGAGGGACGTTGCGAATAGGCAGCTCGTGGCGTCG CGGCAGAAGATGCAGAGGATTGGGGATTCGTTGAAGAGATTATGCGGAGTGGATGGAGGAGCTTTGTAG
Transcript	>Ophun1\|199 ATGACGGATGATCTCTACTGGCCTGTCACTGCCGAGGTGCGTATCCCTGGTCAAGGCGGTCGGAGCAGCGGACGG GATTTTATGGCGCTGGTGGCTGTTGTCATCGTCACCGTTTCTCTCTCACTGTCTGGTCTATTCATCGGTGCGCAT CTGGCTTTGGCGACGGAGAGGATTCCACCATCGTTACCTCAGCCGGCGACGAGGCGCTTCATCGACCCAGCTGGC GTCTTCCTCGGTTGGGGAGGCTGGCTAGCATCCATCCTCCTCTGCGCCCTCCTCCCCCACCGCTCATGGCGAGGC ATCCTCTTCGCCCTCGTCTTCGCGCCTCTAGGAACCCTCCTACGCTTCCGCCTAGCCCTCTGGCTCAACGGAGCC CGTCCATCCTTCCCGCTCGGCACCTTCACGGCTAACATGGTGGGTACGGCGGTGCTGGGCATGGCGTGGGATCTC GAGCACGTGCCCATCGGGGGCGTTGTCGGATGTCAGGTGCTGATGGGCGTTGGCGATGGTTTCTGCGGCTGCTTG ACGACGGTTTCGACTTGGGTTGCTGAGTTGAGTGGTCTCGGCCAGTCTCGGCCAGCATCTCATACTCTCGGCGCC TCACTGGCCATCATCATCGTCATCCCAGTCATCATGATCATAGAATACACCGATAGGACACCGGCGCCGGCGTCG GTGCCATCCATCATGATTACCCCCCCGATCACGGACTTGACGAAACCGCTCAGGGCCATGCCTCGTCCGATATGC GCCGCCGAAACAGAACACAAGGGGGAACTCTGCGGCGCCGAGCCTCGCCTCATATGCCCCTACTGCTACATCTTT GCGTACTGCTCTTCTAGCTGCAGACGGCGTCACTGGAAGGAGTCCCATCATAAGGAGTGCCAGAAGGCCATCGAC ATGGCGCTGCCGGATGGATGGACCGTCGACAATCCTGTTGCCTTGGGCGACTGGCTCTCTTCGCAAAAGACGTAT TGGCACAACTATCCGGCCACCGACGTTCTGCGGCTGGATAAAACAGAGGGCGCGTGGTTCGAGTCTAGCCTCAAC ATGCTCTTCTATGGGGCTGCGGGCATACGCCATCTGATCTACAGCGTCGCCAACATGGTCGATACAGCCAGGCCT CAGCTGAATGTCGTCGTCGACGAGCACCATTTCTCTCATTATCTACGCTCTTTTCTGGCCCTACACCTTCTCGCG GCCAACGGCTTCGACCCTGTGGACAACGCCGAGGCCGTCATCCACATGTGGTATTCGTCACTGCTGCCCAGGCGG ATCCATGATCACATTCGAGCCGTGGTCAGGGCCAACACGGACGGCTTCTTCGACAGCAAAAAGGAGCTGAAAAAG GGGAAATTGTCGTTGCTGACTTGGGGCACTGGCCATCAGTTGTTCGAGGCGGCCATGACCCAGAGAGACTTTGAC GTTATCTGCGACTTTTTTGACGATACGTCGACTCAAATCCGTCTTGATGAAGCCTGCCGCTTCGTGGACAGGAAC AAAGACATCGAGCCTGTTGAAGGACTGCTGGCTCGGATGGATCGTTCTCGCTGTCTTAGCCTGCTCAAATGGCGT GAAGACGGCCTATTTCTGCCCTACACCTATTCTCGCCATGAGTTTGATATGCTCAACCCTATCATTTACAGCAAA AACTGGCCTTTTCAGAAAGGCGTATCGTCTGAGCCCCTGACGGAGTGGCCCATGGAGATTCTCGACTTCGACTGT GGTCCTGCCACGGAAGACATGTACGGCAAGGCCTACTTTTACCTTCACGATCTCTTTGTGCGCTTTCAAGGCAGG CTGGCCGACATGTCCGTGCGGATACGGGTGGCAGGGAGGGCCATTGTCGACATCGATCCCAGGCTGTACTTTCTG CCCTGGGGGGATCTTCACGACCGCATCGAGGTTGGCGAGACGTGGGATACGGCACCCTTGACGGCCACCGTCTTC GCGTCTCGATTCCTGCGACCGACTCAGCACAACCCATTCGCGACGGCATTGATGATGACGAAAGAGTCGTTGAAT AGGCCTTGTGTCGTTACCGAGACAGAAGCGGCGCAGGAGAACGCCAAGCTGCTCAAAAAGACGGGTCTGGCTCTC GATCAGCTGGCGCCGCCTGTCAAGAATGTCACGGATGATCCCAAAATGACGGCTCGTCGTGCCCTTGCCCTCGTG CTGTGGCGCGACTGGGACAAGTTCTCAGACGCCTTTCTCGAATCGCCTACTCACTTTGGCTTCAACTCCATATCC TTCTCGACGTCCGAGTCCAAGTCAGCCATCCTCGTCGATGAAAGCATTATCCGCCTGAAGCCGAAGCTCAAGTCG AAGCCGAATCCGAACCCGCGCAGCATCGTCGAGGAGGGCTTCCTTGGCCTGCACATGCAAAGGCAGAATACCATC ACTCAACGCTTCCCGAACCGAGTCGTCCACAAGGCTGCGGACGTGCCTTGCGTCGACGAGTTTGAACGTTGGATG AGCTGGGCGAGTGTCAAGCCTCAGCGATGGCTGGAGTGGAAGCGCGTTGGGGACGAGGCTGACTGCGACTTTGAC GAATGGATGCTTTGGGTTTCGCTTACTGTCAAGCACTTGGCGGACGAGATCGAGTTGATCCTGGCTCAGAGCTTG CTCGAAGACCCGATTGATCGTGTTTGGATGAGCAAGGTAGGGTCCACGGGCGAGACGACGCTTTGGGGTCCGAGG GAGACCGGCACGTCGGAGAAGCTTGAGGGTCGGTTCTGGGACGAGGTCAGGGCGGGGGTTGCGAGGGGGGATATC AAATGGGTGCCTATTGTCCGAGTTGACTGTGACTATGGTGATGGTGGTCTTGATCAGATCAAGAAGGACGAGAAG GGCAAGGGCAAGGCTGGGGAAGAAGAGTCGTCTGGGGGGAGTGATGGAGATTTGGAGGAGGGGGAGATGGTCGAG GTCGACGAGCAGGGAGAGCTGTCTTTTGCCAGTCAGTTGGGAAAGGGGAAGGCGAAGGAGGTTGACATCGGCAAG CCGCTCGAGATCAAAAAGTCGGTTGAGACCAGCAACCCATTCGAAGATCCGCCTCCCGGCTACACCGAAATGAAC GAGCAGACAAGGGCACTCGAGCCGGAATCCAGCAGGCCAGCCGAGGAAGACACCGTCCAGACCAGCAAGCCGAAG AAGAAGAAGAAGAACAAAAAGAAGAAGAAGAAGAAGTCCAAGGGAAAAGGCCAGGCGTCTGGTCAGCCAGCCGAC GAGCACTCGGACTTTACTTCAGCGAATACCGACGACAGTGATGCCATGGACGCGGACACAGAGACGCTGTCTGGA GACGAACTCGTCCGTTTCCTGATGCAGAAGCTGGAGAAGGGCATGGCGGATACGGAGGAGAGGATCATGGAGGCG GAGAAGGGGAACCGTCTGAGTTTGCACATGGTCGGGCAGATCAAGGCGCTGAGGACGAAGGATCGGAATGCTGAC GATTGGGGGCTGAAGGCCATGGAGGCGGAGATGACGCGGATGAGGGACGTTGCGAATAGGCAGCTCGTGGCGTCG CGGCAGAAGATGCAGAGGATTGGGGATTCGTTGAAGAGATTATGCGGAGTGGATGGAGGAGCTTTGTAG
Gene	>Ophun1\|199 ATGACGGATGATCTCTACTGGCCTGTCACTGCCGAGGTGCGTATCCCTGGTCAAGGCGGTCGGAGCAGCGGACGG GATTTTATGGCGCTGGTGGCTGTTGTCATCGTCACCGTTTCTCTCTCACTGTCTGGTCTATTCATCGGTGCGCAT CTGGCTTTGGCGACGGAGAGGATTCCACCATCGTTACCTCAGCCGGCGACGAGGCGCTTCATCGACCCAGCTGGC GTCTTCCTCGGTTGGGGAGGCTGGCTAGCATCCATCCTCCTCTGCGCCCTCCTCCCCCACCGCTCATGGCGAGGC ATCCTCTTCGCCCTCGTCTTCGCGCCTCTAGGAACCCTCCTACGCTTCCGCCTAGCCCTCTGGCTCAACGGAGCC CGTCCATCCTTCCCGCTCGGCACCTTCACGGCTAACATGGTGGGTACGGCGGTGCTGGGCATGGCGTGGGATCTC GAGCACGTGCCCATCGGGGGCGTTGTCGGATGTCAGGTGCTGATGGGCGTTGGCGATGGTTTCTGCGGCTGCTTG ACGACGGTTTCGACTTGGGTTGCTGAGTTGAGTGGGTTGAGGAGGAGGCATGCTTGGGTTTATGGGGGGGGGAGT GTTGTTGTTGCTTTTGCGCTGTTGGTGCTCATCATGGGGGGGTTGCGATGGACTCGGGGGTTTGCGATGATGGAG TGTCATTAGGGGAAGGGAAGGGGAGGGGGAGGTGGAAGAAGAGGAAGAAGACGATGGAGAGCTCGGTGCCTGCCT CTCTCTGGGCTTGTCTCGTCTCTTCCACCCCCTTCCTCGTCGCCTCTCTTTCTTTCTAACGGATTGCCTCGGATT TGGCCTCAGTCTCGGCCAGTCTCGGCCAGCATCTCATACTCTCGGCGCCTCACTGGCCATCATCATCGTCATCCC AGTCATCATGATCATAGAATACACCGATAGGACACCGGCGCCGGCGTCGGTGCCATCCATCATGATTACCCCCCC GATCACGGACTTGACGAAACCGCTCAGGGCCATGCCTCGTCCGATATGCGCCGCCGAAACAGAACACAAGGGGGA ACTCTGCGGCGCCGAGCCTCGCCTCATATGCCCCTACTGCTACATCTTTGCGGTGAGGCGGAATCCCGCTGTGCG AGATCATGATGGGATCGCTGACGGGTCTTCTCTTCACGCAGTACTGCTCTTCTAGCTGCAGACGGCGTCACTGGA AGGAGTCCCATCATAAGGAGTGCCAGAAGGCCATCGACATGGCGCTGCCGGATGGATGGACCGTCGACAATCCTG TTGCCTTGGGCGACTGGCTCTCTTCGCAAAAGACGTATTGGCACAACTATCCGGCCACCGACGTTCTGCGGCTGG ATAAAACAGAGGGCGCGTGGTTCGAGTCTAGCCTCAACATGCTCTTCTATGGGGGTTCGTCTGAGCCCTTCACTC CGTCTGCTTGGCTGTCGATGCAATGACTGACTGATGTTCTCAGCTGCGGGCATACGCCATCTGATCTACAGCGTC GCCAACATGGTCGATACAGCCAGGCCTCAGCTGAATGTCGTCGTCGACGAGCACCATTTCTCTCATTATCTACGC TCTTTTCTGGCCCTACACCTTCTCGCGGCCAACGGCTTCGACCCTGTGGACAACGCCGAGGCCGTCATCCACATG TGGTATTCGTCACTGCTGCCCAGGCGGATCCATGATCACATTCGAGCCGTGGTCAGGGCCAACACGGACGGCTTC TTCGACAGCAAAAAGGAGCTGAAAAAGGGGAAATTGTCGTTGCTGACTTGGGGCACTGGCCATCAGTTGTTCGAG GCGGCCATGACCCAGAGAGACTTTGACGTTATCTGCGACTTTTTTGACGATACGTCGACTCAAATCCGTCTTGAT GAAGCCTGCCGCTTCGTGGACAGGAACAAAGACATCGAGCCTGTTGAAGGACTGCTGGCTCGGATGGATCGTTCT CGCTGTCTTAGCCTGCTCAAATGGCGTGAAGACGGCCTATTTCTGCCCTACACCTATTCTCGCCATGAGTTTGAT ATGCTCAACCCGTGAGAAGGACCTCGTTGTTTCTTGTTAGTCTTGGATGCTGACGACCGAGGCAGTATCATTTAC AGCAAAAACTGGCCTTTTCAGAAAGGCGTATCGTCTGAGCCCCTGACGGAGTGGCCCATGGAGATTCTCGACTTC GACTGTGGTCCTGCCACGGAAGACATGTACGGCAAGGCCTACTTTTACCTTCACGATCTCTTTGTGCGCTTTCAA GGCAGGCTGGCCGACATGTCCGTGCGGATACGGGTGGCAGGGAGGGCCATTGTCGACATCGATCCCAGGCTGTAC TTTCTGCCCTGGGGGGATCTTCACGACCGCATCGAGGTGAGCAACTGATCCATCTTTTCTCTTTCTGTGCTGGGC TCATTCTATATATACAGGTTGGCGAGACGTGGGATACGGCACCCTTGACGGCCACCGTCTTCGCGTCTCGATTCC TGCGACCGACTCAGCACAACCCATTCGCGACGGCATTGATGATGACGAAAGAGTCGTTGAATAGGCCTTGTGTCG TTACCGAGACAGAAGCGGCGCAGGAGAACGCCAAGCTGCTCAAAAAGACGGGTCTGGCTCTCGATCAGCTGGCGC CGCCTGTCAAGAATGTCACGGATGATCCCAAAATGACGGCTCGTCGTGCCCTTGCCCTCGTGCTGTGGCGCGACT GGGACAAGTTCTCAGACGCCTTTCTCGAATCGCCTACTCACTTTGGCTTCAACTCCATATCCTTCTCGACGTCCG AGTCCAAGTCAGCCATCCTCGTCGATGAAAGCATTATCCGCCTGAAGCCGAAGCTCAAGTCGAAGCCGAATCCGA ACCCGCGCAGCATCGTCGAGGAGGGCTTCCTTGGCCTGCACATGCAAAGGCAGAATACCATCACTCAACGCTTCC CGAACCGAGTCGTCCACAAGGCTGCGGACGTGCCTTGCGTCGACGAGTTTGAACGTTGGATGAGCTGGGCGAGTG TCAAGCCTCAGCGATGGCTGGAGTGGAAGCGCGTTGGGGACGAGGCTGACTGCGACTTTGACGAATGGATGCTTT GGGTTTCGCTTACTGTCAAGCACTTGGCGGACGAGATCGAGTTGATCCTGGCTCAGAGCTTGCTCGAAGACCCGA TTGATCGTGTTTGGATGAGCAAGGTAGGGTCCACGGGCGAGACGACGCTTTGGGGTCCGAGGGAGACCGGCACGT CGGAGAAGCTTGAGGGTCGGTTCTGGGACGAGGTCAGGGCGGGGGTTGCGAGGGGGGATATCAAATGGGTGCCTA TTGTCCGAGTTGACTGTGACTATGGTGATGGTGGTCTTGATCAGATCAAGAAGGACGAGAAGGGCAAGGGCAAGG CTGGGGAAGAAGAGTCGTCTGGGGGGAGTGATGGAGATTTGGAGGAGGGGGAGATGGTCGAGGTCGACGAGCAGG GAGAGCTGTCTTTTGCCAGTCAGTTGGGAAAGGGGAAGGCGAAGGAGGTTGACATCGGCAAGCCGCTCGAGATCA AAAAGTCGGTTGAGACCAGCAACCCATTCGAAGATCCGCCTCCCGGCTACACCGAAATGAACGAGCAGACAAGGG CACTCGAGCCGGAATCCAGCAGGCCAGCCGAGGAAGACACCGTCCAGACCAGCAAGCCGAAGAAGAAGAAGAAGA ACAAAAAGAAGAAGAAGAAGAAGTCCAAGGGAAAAGGCCAGGCGTCTGGTCAGCCAGCCGACGAGCACTCGGACT TTACTTCAGCGAATACCGACGACAGTGATGCCATGGACGCGGACACAGAGACGCTGTCTGGAGACGAACTCGTCC GTTTCCTGATGCAGAAGCTGGAGAAGGGCATGGCGGATACGGAGGAGAGGATCATGGAGGCGGAGAAGGGGAACC GTCTGAGTTTGCACATGGTCGGGCAGATCAAGGCGCTGAGGACGAAGGATCGGAATGCTGACGATTGGGGGCTGA AGGCCATGGAGGCGGAGATGACGCGGATGAGGGACGTTGCGAATAGGCAGCTCGTGGCGTCGCGGCAGAAGATGC AGAGGATTGGGGATTCGTTGAAGAGTGTGAGCAAGGTGGAGATGATGGCGGCGCTCAAGGAGTTGGCTGAGGAAG AGGGGGAGGATTATGCGGAGTGGATGGAGGAGCTTTGTAG

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