Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophio5|7070
Gene name
Location	scaffold_656:5960..9516
Strand	-
Gene length (bp)	3556
Transcript length (bp)	3039
Coding sequence length (bp)	3036
Protein length (aa)	1012

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF06032	DUF917	Protein of unknown function (DUF917)	2.2E-117	623	990
PF05378	Hydant_A_N	Hydantoinase/oxoprolinase N-terminal region	6.7E-25	5	183
PF01968	Hydantoinase_A	Hydantoinase/oxoprolinase	1.7E-17	205	392

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|Q01262|HYUA_PSESN	Hydantoin utilization protein A OS=Pseudomonas sp. (strain NS671) GN=hyuA PE=3 SV=1	6	393	8.0E-13

GO

GO Term	Description	Terminal node
GO:0016787	hydrolase activity	Yes
GO:0003824	catalytic activity	No
GO:0003674	molecular_function	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 35	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
SC16a	Pure fungal culture	24.80	13.42	36.18
CcL	In ants, during behavior modification	17.74	9.35	26.13
CcD	In ants, recently dead	15.84	8.21	23.47

Differential expression

Label1	Label2	Q-value	Significant difference
SC16a	CcL	0.158083	no
SC16a	CcD	0.045635	yes
CcL	CcD	0.676078	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophio5|7070 MSSYRIGVDVGGTNTDAAILDISALDQPGRGVLASHKTLTTADITSGIEAAIRAVLADSGVDQDHVLSVTIGTTH FINALVEADARRLDRVAVIRLCGPFTRQLPPFSGFPVGLRRIIEGGLHYIDGGLEMNGREIAPLDPHQIRRVAAE IVAAGISAVALVGVFSPLDHDGIHEERCRELLLREAPGLRVVCSRSIGSTGLLERENATILNAAILRTARHVKRG FRRAMGRLRLRCPLFLSQNDGTLIDADVAAELPIKTFASGPTNSMTGAAFLAGIDRAAPAADAEGPQVLVVDIGG TTTDICALLPSGFPRQAPGFVDVGGVRTAFSMPEVLSVGLGGGSKVVVTPDPHRPGFDLVSVGPASVGHRLREEA RVFGGSTLTATDAIAAAGGNDLGDAALVADVPRTTIDLACQDIRHKLETIIDRMRVSAAPVHVLLVGGGAILVRE ELAGVDKCIRPVHQGAANAVGAAIAKVSGEVDSLEILGRRQEREIIDAACSRAVDLAVEKGASRDDVRVVEINKT PLQYMSQETIRIQVRAVGKLAIPVGPAPSRSSAGDAEPPVTGEADDDRDEDDDDDNDDAPKVSIPDALEPTTKPT LGVDLATYRPDVRAGVWYVSEIDLELIATGCGVLGTGGGGPTYYEYLKCLNSRRGPGGDKMRIISAQSLADDDVV CFGAWYGSPSVINERIPGGNEIAAAIDAVNLIKGNDSFAALCLDEIGGGNGMCALPNCVRYDCPVIDGDAMGRAY PTLYHTSFCVYGYSMTPCTVTDAAGNVVVATKTDNPFRLETLIRTASVEMGLSCASSPNPLPASAVKAHGVPNTI SQAWYLGRAVHMARRSKANYVDAIFSVCDGKLLFTGKITDVHRYIGGGYTMGAVLLAPLSDEERESPANASRQQV PTDKHMIIPFQNEYLYAAHCDALGSEPSREVVCTVPSLISILGQDGEAIGSQDLRYGLRVNVIALPAHPLWRTPE ALKVGGPEGFGLNMPEVGVETCEEFKGARSVIDEFRE
Coding	>Ophio5|7070 ATGTCGTCATACCGGATCGGCGTCGACGTCGGCGGCACCAACACGGATGCCGCCATCCTTGACATCAGCGCCCTC GACCAGCCCGGACGCGGCGTGTTGGCCTCACACAAGACCTTGACGACGGCCGACATTACCAGCGGCATCGAGGCC GCGATCCGGGCCGTATTGGCGGACTCGGGCGTCGACCAGGACCACGTCCTCAGCGTCACCATCGGCACGACACAC TTTATCAACGCCCTGGTCGAGGCCGATGCCCGCCGGCTCGATCGCGTGGCCGTCATCCGACTCTGCGGGCCCTTT ACGCGCCAGCTGCCTCCCTTTTCCGGCTTCCCGGTTGGCCTCAGACGGATCATTGAGGGCGGCCTTCACTACATC GATGGCGGGCTGGAGATGAACGGCCGGGAGATCGCACCTCTGGACCCGCATCAGATCCGGCGCGTGGCCGCAGAG ATAGTGGCCGCCGGCATCTCCGCCGTCGCCCTCGTAGGCGTCTTCTCGCCCCTGGACCACGACGGCATCCACGAG GAGCGGTGCCGTGAGCTGCTTCTGCGAGAGGCGCCCGGTCTACGCGTCGTCTGCTCTCGTAGCATCGGCTCAACC GGCCTCCTGGAGCGTGAGAACGCGACGATTCTGAACGCGGCCATCCTTCGCACCGCCCGTCACGTCAAGCGTGGC TTCAGACGCGCCATGGGCCGTCTCCGTCTGCGTTGTCCCTTGTTTCTGTCGCAGAATGACGGCACGCTCATCGAC GCCGACGTCGCCGCCGAGCTGCCCATCAAGACTTTTGCCAGCGGGCCGACCAACAGTATGACGGGCGCCGCCTTT CTAGCCGGCATCGACCGCGCTGCCCCCGCTGCCGACGCCGAGGGCCCCCAGGTGCTGGTGGTGGACATTGGCGGC ACTACGACGGACATCTGCGCCCTGCTACCCTCGGGCTTCCCCCGTCAGGCACCGGGCTTCGTCGACGTCGGCGGG GTCCGGACCGCTTTTTCTATGCCCGAGGTCCTCTCCGTCGGTCTCGGCGGCGGAAGCAAAGTGGTCGTGACGCCG GACCCACACCGGCCCGGCTTCGACCTCGTCTCCGTCGGCCCGGCCTCGGTCGGCCACCGGCTCCGGGAGGAGGCC CGCGTCTTCGGCGGATCGACGCTGACGGCAACCGACGCCATCGCGGCCGCCGGCGGCAATGACCTCGGCGACGCC GCCCTCGTCGCCGACGTACCCCGGACCACCATTGACCTCGCCTGCCAAGACATACGGCACAAGCTCGAGACCATC ATCGACCGTATGAGGGTCTCTGCCGCGCCTGTCCACGTGCTACTCGTCGGTGGCGGCGCCATCCTCGTCAGGGAA GAGCTGGCCGGTGTGGACAAGTGCATCCGTCCCGTTCATCAGGGCGCGGCCAACGCCGTCGGAGCGGCCATCGCA AAGGTCTCGGGCGAGGTCGATAGTCTCGAGATTTTGGGCCGTAGGCAAGAGAGGGAGATTATCGACGCTGCCTGC AGCCGTGCTGTCGACCTGGCCGTCGAAAAGGGCGCCAGCCGTGACGACGTACGAGTCGTCGAGATCAATAAGACG CCTCTTCAGTACATGTCGCAGGAGACGATCCGCATCCAGGTCCGCGCCGTCGGTAAGCTCGCCATCCCGGTCGGC CCTGCTCCGAGCCGGTCAAGTGCTGGAGATGCGGAGCCTCCGGTGACGGGCGAGGCCGACGACGACCGAGACGAA GATGATGATGACGACAACGACGACGCACCCAAGGTCAGCATCCCCGACGCCCTAGAACCAACCACCAAGCCGACG CTCGGCGTGGACCTGGCCACATACCGGCCGGACGTCCGTGCCGGCGTCTGGTACGTGTCCGAGATCGATCTTGAG CTCATCGCCACCGGCTGCGGCGTCCTCGGCACCGGCGGCGGCGGCCCGACTTACTACGAGTATCTCAAGTGTCTC AACAGCCGTCGCGGACCGGGCGGTGACAAGATGAGGATCATCTCGGCCCAGTCGCTCGCCGACGACGACGTCGTC TGCTTCGGCGCCTGGTACGGCAGTCCGAGCGTCATCAACGAGCGTATCCCGGGCGGCAACGAGATCGCCGCTGCC ATCGACGCCGTTAATCTCATCAAGGGGAACGACTCCTTTGCCGCTCTCTGCCTCGACGAGATCGGAGGCGGCAAC GGCATGTGTGCCTTGCCCAATTGCGTACGCTACGACTGCCCCGTAATCGACGGCGATGCCATGGGACGAGCCTAT CCAACCCTGTACCACACCAGCTTCTGCGTCTACGGCTACAGCATGACGCCTTGTACCGTCACAGATGCCGCCGGC AACGTCGTCGTGGCTACCAAAACCGATAACCCCTTCCGCCTCGAGACGCTCATCCGAACGGCATCCGTCGAGATG GGCTTGTCGTGCGCATCGAGTCCTAATCCGCTTCCAGCATCGGCCGTCAAGGCGCATGGCGTGCCAAACACCATA TCGCAGGCCTGGTATCTGGGCCGAGCTGTGCACATGGCCAGGCGTAGTAAGGCGAACTATGTAGATGCCATTTTC AGCGTCTGCGACGGAAAGCTGCTCTTCACGGGGAAGATCACCGACGTCCACCGCTATATCGGCGGCGGGTATACC ATGGGCGCCGTCCTGCTCGCCCCTCTGAGTGACGAGGAGCGCGAATCGCCAGCCAACGCCAGCCGCCAACAAGTC CCAACAGACAAGCACATGATCATTCCGTTCCAGAACGAGTATCTGTACGCCGCTCACTGCGATGCACTGGGATCC GAGCCGTCGAGGGAGGTCGTATGCACCGTCCCGAGTCTCATCTCCATCTTGGGCCAAGACGGCGAGGCCATTGGA TCTCAAGACTTGCGGTACGGTCTCCGCGTCAACGTCATCGCCCTGCCGGCGCATCCGCTATGGCGAACTCCGGAA GCACTGAAGGTAGGTGGCCCGGAGGGCTTCGGCTTGAACATGCCCGAAGTCGGTGTCGAGACGTGCGAAGAGTTT AAGGGGGCAAGGAGCGTCATAGACGAATTTAGGGAG
Transcript	>Ophio5|7070 ATGTCGTCATACCGGATCGGCGTCGACGTCGGCGGCACCAACACGGATGCCGCCATCCTTGACATCAGCGCCCTC GACCAGCCCGGACGCGGCGTGTTGGCCTCACACAAGACCTTGACGACGGCCGACATTACCAGCGGCATCGAGGCC GCGATCCGGGCCGTATTGGCGGACTCGGGCGTCGACCAGGACCACGTCCTCAGCGTCACCATCGGCACGACACAC TTTATCAACGCCCTGGTCGAGGCCGATGCCCGCCGGCTCGATCGCGTGGCCGTCATCCGACTCTGCGGGCCCTTT ACGCGCCAGCTGCCTCCCTTTTCCGGCTTCCCGGTTGGCCTCAGACGGATCATTGAGGGCGGCCTTCACTACATC GATGGCGGGCTGGAGATGAACGGCCGGGAGATCGCACCTCTGGACCCGCATCAGATCCGGCGCGTGGCCGCAGAG ATAGTGGCCGCCGGCATCTCCGCCGTCGCCCTCGTAGGCGTCTTCTCGCCCCTGGACCACGACGGCATCCACGAG GAGCGGTGCCGTGAGCTGCTTCTGCGAGAGGCGCCCGGTCTACGCGTCGTCTGCTCTCGTAGCATCGGCTCAACC GGCCTCCTGGAGCGTGAGAACGCGACGATTCTGAACGCGGCCATCCTTCGCACCGCCCGTCACGTCAAGCGTGGC TTCAGACGCGCCATGGGCCGTCTCCGTCTGCGTTGTCCCTTGTTTCTGTCGCAGAATGACGGCACGCTCATCGAC GCCGACGTCGCCGCCGAGCTGCCCATCAAGACTTTTGCCAGCGGGCCGACCAACAGTATGACGGGCGCCGCCTTT CTAGCCGGCATCGACCGCGCTGCCCCCGCTGCCGACGCCGAGGGCCCCCAGGTGCTGGTGGTGGACATTGGCGGC ACTACGACGGACATCTGCGCCCTGCTACCCTCGGGCTTCCCCCGTCAGGCACCGGGCTTCGTCGACGTCGGCGGG GTCCGGACCGCTTTTTCTATGCCCGAGGTCCTCTCCGTCGGTCTCGGCGGCGGAAGCAAAGTGGTCGTGACGCCG GACCCACACCGGCCCGGCTTCGACCTCGTCTCCGTCGGCCCGGCCTCGGTCGGCCACCGGCTCCGGGAGGAGGCC CGCGTCTTCGGCGGATCGACGCTGACGGCAACCGACGCCATCGCGGCCGCCGGCGGCAATGACCTCGGCGACGCC GCCCTCGTCGCCGACGTACCCCGGACCACCATTGACCTCGCCTGCCAAGACATACGGCACAAGCTCGAGACCATC ATCGACCGTATGAGGGTCTCTGCCGCGCCTGTCCACGTGCTACTCGTCGGTGGCGGCGCCATCCTCGTCAGGGAA GAGCTGGCCGGTGTGGACAAGTGCATCCGTCCCGTTCATCAGGGCGCGGCCAACGCCGTCGGAGCGGCCATCGCA AAGGTCTCGGGCGAGGTCGATAGTCTCGAGATTTTGGGCCGTAGGCAAGAGAGGGAGATTATCGACGCTGCCTGC AGCCGTGCTGTCGACCTGGCCGTCGAAAAGGGCGCCAGCCGTGACGACGTACGAGTCGTCGAGATCAATAAGACG CCTCTTCAGTACATGTCGCAGGAGACGATCCGCATCCAGGTCCGCGCCGTCGGTAAGCTCGCCATCCCGGTCGGC CCTGCTCCGAGCCGGTCAAGTGCTGGAGATGCGGAGCCTCCGGTGACGGGCGAGGCCGACGACGACCGAGACGAA GATGATGATGACGACAACGACGACGCACCCAAGGTCAGCATCCCCGACGCCCTAGAACCAACCACCAAGCCGACG CTCGGCGTGGACCTGGCCACATACCGGCCGGACGTCCGTGCCGGCGTCTGGTACGTGTCCGAGATCGATCTTGAG CTCATCGCCACCGGCTGCGGCGTCCTCGGCACCGGCGGCGGCGGCCCGACTTACTACGAGTATCTCAAGTGTCTC AACAGCCGTCGCGGACCGGGCGGTGACAAGATGAGGATCATCTCGGCCCAGTCGCTCGCCGACGACGACGTCGTC TGCTTCGGCGCCTGGTACGGCAGTCCGAGCGTCATCAACGAGCGTATCCCGGGCGGCAACGAGATCGCCGCTGCC ATCGACGCCGTTAATCTCATCAAGGGGAACGACTCCTTTGCCGCTCTCTGCCTCGACGAGATCGGAGGCGGCAAC GGCATGTGTGCCTTGCCCAATTGCGTACGCTACGACTGCCCCGTAATCGACGGCGATGCCATGGGACGAGCCTAT CCAACCCTGTACCACACCAGCTTCTGCGTCTACGGCTACAGCATGACGCCTTGTACCGTCACAGATGCCGCCGGC AACGTCGTCGTGGCTACCAAAACCGATAACCCCTTCCGCCTCGAGACGCTCATCCGAACGGCATCCGTCGAGATG GGCTTGTCGTGCGCATCGAGTCCTAATCCGCTTCCAGCATCGGCCGTCAAGGCGCATGGCGTGCCAAACACCATA TCGCAGGCCTGGTATCTGGGCCGAGCTGTGCACATGGCCAGGCGTAGTAAGGCGAACTATGTAGATGCCATTTTC AGCGTCTGCGACGGAAAGCTGCTCTTCACGGGGAAGATCACCGACGTCCACCGCTATATCGGCGGCGGGTATACC ATGGGCGCCGTCCTGCTCGCCCCTCTGAGTGACGAGGAGCGCGAATCGCCAGCCAACGCCAGCCGCCAACAAGTC CCAACAGACAAGCACATGATCATTCCGTTCCAGAACGAGTATCTGTACGCCGCTCACTGCGATGCACTGGGATCC GAGCCGTCGAGGGAGGTCGTATGCACCGTCCCGAGTCTCATCTCCATCTTGGGCCAAGACGGCGAGGCCATTGGA TCTCAAGACTTGCGGTACGGTCTCCGCGTCAACGTCATCGCCCTGCCGGCGCATCCGCTATGGCGAACTCCGGAA GCACTGAAGGTAGGTGGCCCGGAGGGCTTCGGCTTGAACATGCCCGAAGTCGGTGTCGAGACGTGCGAAGAGTTT AAGGGGGCAAGGAGCGTCATAGACGAATTTAGGGAGTAA
Gene	>Ophio5|7070 ATGTCGTCATACCGGATCGGCGTCGACGTCGGCGGCACCAACACGGATGCCGCCATCCTTGACATCAGCGCCCTC GACCAGCCCGGACGCGGCGTGTTGGCCTCACACAAGACCTTGACGACGGCCGACATTACCAGCGGCATCGAGGCC GCGATCCGGGCCGTATTGGCGGACTCGGGCGTCGACCAGGACCACGTCCTCAGCGTCACCATCGGCACGACACAC TTTATCAACGCCCTGGTCGAGGCCGATGCCCGCCGGCTCGATCGCGTGGCCGTCATCCGACTCTGCGGGCCCTTT ACGCGCCAGCTGCCTCCCTTTTCCGGCTTCCCGGTTGGCCTCAGACGGATCATTGAGGGCGGCCTTCACTACATC GATGGCGGGCTGGAGATGAACGGCCGGGAGATCGCACCTCTGGACCCGCATCAGATCCGGCGCGTGGCCGCAGAG ATAGTGGCCGCCGGCATCTCCGCCGTCGCCCTCGTAGGCGTCTTCTCGCCCCTGGACCACGACGGCATCCACGAG GAGCGGTGCCGTGAGCTGCTTCTGCGAGAGGCGCCCGGTCTACGCGTCGTCTGCTCTCGTAGCATCGGCTCAACC GGCCTCCTGGAGCGTGAGAACGCGACGATTCTGAACGCGGCCATCCTTCGCACCGCCCGTCACGTCAAGCGTGGC TTCAGACGCGCCATGGGCCGTCTCCGTCTGCGTTGTCCCTTGTTTCTGTCGCAGAATGACGGCACGCTCATCGAC GCCGACGTCGCCGCCGAGCTGCCCATCAAGACTTTTGCCAGCGGGCCGACCAACAGTATGACGGGCGCCGCCTTT CTAGCCGGCATCGACCGCGCTGCCCCCGCTGCCGACGCCGAGGGCCCCCAGGTGCTGGTGGTGGACATTGGCGGC ACTACGACGGACATCTGCGCCCTGCTACCCTCGGGCTTCCCCCGTCAGGCACCGGGCTTCGTCGACGTCGGCGGG GTCCGGACCGCTTTTTCTATGCCCGAGGTCCTCTCCGTCGGTCTCGGCGGCGGAAGCAAAGTGGTCGTGACGCCG GACCCACACCGGCCCGGCTTCGACCTCGTCTCCGTCGGCCCGGCCTCGGTCGGCCACCGGCTCCGGGAGGAGGCC CGCGTCTTCGGCGGATCGACGCTGACGGCAACCGACGCCATCGCGGCCGCCGGCGGCAATGACCTCGGCGACGCC GCCCTCGTCGCCGACGTACCCCGGACCACCATTGACCTCGCCTGCCAAGACATACGGCACAAGCTCGAGACCATC ATCGACCGTATGAGGGTCTCTGCCGCGCCTGTCCACGTGCTACTCGTCGGTGGCGGCGCCATCCTCGTCAGGGAA GAGCTGGCCGGTGTGGACAAGTGCATCCGTCCCGTTCATCAGGGCGCGGCCAACGCCGTCGGAGCGGCCATCGCA AAGGTCTCGGGCGAGGTCGATAGTCTCGAGATTTTGGGCCGTAGGCAAGAGAGGGAGATTATCGACGCTGCCTGC AGCCGTGCTGTCGACCTGGCCGTCGAAAAGGGCGCCAGCCGTGACGACGTACGAGTCGTCGAGATCAATAAGACG CCTCTTCAGTACATGTCGCAGGAGACGATCCGCATCCAGGTCCGCGCCGTCGGTAAGCTCGCCATCCCGGTCGGC CCTGCTCCGAGCCGGTCAAGTGCTGGAGATGCGGAGCCTCCGGTGACGGGCGAGGCCGACGACGACCGAGACGAA GATGATGATGACGACAACGACGACGCACCCAAGGTCAGCATCCCCGACGCCCTAGAACCAACCACCAAGCCGACG CTCGGCGTGGACCTGGCCACATACCGGCCGGACGTCCGTGCCGGCGTCTGGTACGTGTCCGAGATCGATCTTGAG CTCATCGCCACCGGCTGCGGCGTCCTCGGCACCGGCGGCGGCGGCCCGACTTACTACGAGTATCTCAAGTGTCTC AACAGCCGTCGCGGACCGGGCGGTGACAAGATGAGGATCATCTCGGCCCAGTCGCTCGCCGACGACGACGTCGTC TGCTTCGGCGCCTGGTACGGCAGTCCGAGCGTCATCAACGAGCGTATCCCGGGCGGCAACGAGATCGCCGCTGCC ATCGACGCCGTTAATCTCATCAAGGGGAACGACTCCTTTGCCGCTCTCTGCCTCGACGAGATGTACGTCTTGAGT TTTTTTACCCCAGCTTTTGGCATCCTGAGCCCCTGACCCCCCTAACTGACTCGGCCAACCCCCATCCCAGCGGAG GCGGCAACGGCATGTGTGCCTTGCCCAATTGCGTACGCTACGACTGCCCCGTAATCGACGGCGATGCCATGGGAC GAGCCTATCCAACCCTGTACCACAGTGAGTCCTTGGCCTTATCCGAGCCCGTCTAGGCTTTTCTCCCTGACGTCG AGAAGCCAGCTTCTGCGTCTACGGCTACAGCATGACGCCTTGTACCGTCACAGATGCCGCCGGCAACGTCGTCGT GGCTACCGTGCGTTTCCCTTCCCCCCCCCCCTTTCTCTACATGGCTCCAAGCAAACAGCCGGCTGATGCAAAAGG CAGAAAACCGATAACCCCTTCCGCCTCGAGACGCTCATCCGAACGGCATCCGTCGAGATGGGCTTGTCGTGCGCA TCGAGTCCTAATCCGCTTCCAGCATCGGCCGTCAAGGCGCATGGCGTGCCAAACACCATATCGCAGGCCTGGTAT CTGGGCCGAGCTGTGCACATGGCCAGGCGTAGTAAGGCGAACTATGTAGATGCCATTGTAAGTGCTCGTCTGTAT CTGTCTCTTCTTGTTCTCTTTGCTCTTTATCAAGTGCTCGTCACTGCCTAATCCTCTTCGTCTTCCTCCGTCTTC GCATTCTTCGATTTCTTACTCAGTTTCCTCCTTCCCCTGATTTTCCTTTCCGTTTATATGCATTCCTTAGTTCTT CCTGGACCTTGTTTCTTCTCTGTGCATTCCCCCCCCCCCCTTTTTATGCCTTCTTTCTTTCTTCCTTGTTTTTCT CTTTCCATCTCTTTCCGACTCCATTTCTGTGTTATTTCTTCCCCTCCACCGCTGACTCGAGTAGTTCAGCGTCTG CGACGGAAAGCTGCTCTTCACGGGGAAGATCACCGACGTCCACCGCTATATCGGCGGCGGGTATACCATGGGCGC CGTCCTGCTCGCCCCTCTGAGTGACGAGGAGCGCGAATCGCCAGCCAACGCCAGCCGCCAACAAGTCCCAACAGA CAAGCACATGATCATTCCGTTCCAGAACGAGTATCTGTACGCCGCTCACTGCGATGCACTGGGATCCGAGCCGTC GAGGGAGGTCGTATGCACCGTCCCGAGTCTCATCTCCATCTTGGGCCAAGACGGCGAGGCCATTGGATCTCAAGA CTTGCGGTACGGTCTCCGCGTCAACGTCATCGCCCTGCCGGCGCATCCGCTATGGCGAACTCCGGAAGCACTGAA GGTAGGTGGCCCGGAGGGCTTCGGCTTGAACATGCCCGAAGTCGGTGTCGAGACGTGCGAAGAGTTTAAGGGGGC AAGGAGCGTCATAGACGAATTTAGGGAGTAA