Fungal Genomics

at Utrecht University

General Properties

Protein ID	Ophio5\|7035
Gene name
Location	scaffold_65:36618..39295
Strand	-
Gene length (bp)	2677
Transcript length (bp)	2259
Coding sequence length (bp)	2256
Protein length (aa)	752

Overview

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF04055	Radical_SAM	Radical SAM superfamily	1.5E-23	412	592
PF08608	Wyosine_form	Wyosine base formation	1.5E-23	597	665

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|O59761\|TYW1_SCHPO	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tyw1 PE=3 SV=1	20	731	0.0E+00
sp\|Q08960\|TYW1_YEAST	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TYW1 PE=1 SV=1	99	747	0.0E+00
sp\|Q08C92\|TYW1_DANRE	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Danio rerio GN=tyw1 PE=2 SV=1	79	735	1.0E-142
sp\|Q8RXN5\|TYW1_ARATH	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Arabidopsis thaliana GN=TYW1 PE=2 SV=1	184	745	3.0E-142
sp\|Q2KHP8\|TYW1_XENLA	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Xenopus laevis GN=tyw1 PE=2 SV=1	310	735	4.0E-142

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|O59761\|TYW1_SCHPO	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tyw1 PE=3 SV=1	20	731	0.0E+00
sp\|Q08960\|TYW1_YEAST	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TYW1 PE=1 SV=1	99	747	0.0E+00
sp\|Q08C92\|TYW1_DANRE	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Danio rerio GN=tyw1 PE=2 SV=1	79	735	1.0E-142
sp\|Q8RXN5\|TYW1_ARATH	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Arabidopsis thaliana GN=TYW1 PE=2 SV=1	184	745	3.0E-142
sp\|Q2KHP8\|TYW1_XENLA	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Xenopus laevis GN=tyw1 PE=2 SV=1	310	735	4.0E-142
sp\|Q8BJM7\|TYW1_MOUSE	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Mus musculus GN=Tyw1 PE=1 SV=1	68	735	6.0E-142
sp\|Q5REF9\|TYW1_PONAB	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Pongo abelii GN=TYW1 PE=2 SV=1	142	735	1.0E-140
sp\|Q9NV66\|TYW1_HUMAN	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Homo sapiens GN=TYW1 PE=2 SV=2	363	735	2.0E-140
sp\|Q8H8N3\|TYW1_ORYSJ	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Oryza sativa subsp. japonica GN=TYW1 PE=2 SV=1	184	730	1.0E-134
sp\|Q6NUM6\|TYW1B_HUMAN	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Homo sapiens GN=TYW1B PE=2 SV=3	404	735	6.0E-110
sp\|Q9V1F9\|TYW1_PYRAB	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=taw1 PE=1 SV=1	366	664	3.0E-54
sp\|O59412\|TYW1_PYRHO	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) GN=taw1 PE=1 SV=1	366	664	7.0E-54
sp\|Q57705\|TYW1_METJA	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) GN=taw1 PE=1 SV=1	353	614	2.0E-41

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GO

GO Term	Description	Terminal node
GO:0051536	iron-sulfur cluster binding	Yes
GO:0003824	catalytic activity	Yes
GO:0051540	metal cluster binding	No
GO:0005488	binding	No
GO:0003674	molecular_function	No

Deeploc

[Help with interpreting the results of Deeploc 2.0]

Localizations	Signals	Cytoplasm	Nucleus	Extracellular	Cell membrane	Mitochondrion	Plastid	Endoplasmic reticulum	Lysosome vacuole	Golgi apparatus	Peroxisome
Endoplasmic reticulum	Signal peptide	0.1561	0.3336	0.0552	0.1394	0.4296	0.0349	0.82	0.2036	0.3609	0.291

SignalP

(None)

Transmembrane Domains

(None)

Transcription Factor Class

(None)

CAZymes

(None)

Secondary Metabolism

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

Click here for more information

Orthologs

Orthofinder run ID	4
Orthogroup	4420
Change Orthofinder run

Species	Protein ID
Ophiocordyceps australis 1348a (Ghana)	OphauG2\|5422
Ophiocordyceps australis map64 (Brazil)	OphauB2\|3883
Ophiocordyceps camponoti-floridani	Ophcf2\|04125
Ophiocordyceps camponoti-rufipedis	Ophun1\|4034
Ophiocordyceps kimflemingae	Ophio5\|7035 (this protein)
Ophiocordyceps subramaniannii	Hirsu2\|9150

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus Download genbank file of locus (reverse complement) The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophio5\|7035 MEALGWHPYLLTIDDVVDLWHAHRTSLILGTVAVLVAIRLFLRRHDDDVELVALPDVYRDEAALSEKTNSGPRRI KGGAVKKAAVKREADVVTAMPPVKLIVFFSSVTDTTTKLALDYRADLAAATDQLARETGRPFLIPEVYDLAEIDL DDFFIAPPMSPAEAGLFYLFLIPSYNVDSINDTLLQHLRETHHDFRIDTAPLASLLGYSVFGYGDREGWPDEAQG FCFQAIELDKCMSKLTGRKRAYPVGMGDVKRHHAQRFAEWAAGVRDVVVDVARTGHLGLGVRGSGNAVESDDDDG GDDGQTLDQGVVLGDVEDLGNMVRAGGSTTKVKPPLAVDFTTYGQQMPVVKEMVPRGSPTYAALTKQGYSIVGTH SGVKICRWTKSALRGRGSCYKYSLYGINSHQCMETTPSLSCSNKCVFCWRHGTNPVGTTWRWVVDPPDLILRGVK EGHYSKIRMMRGVPGVRAERYAEALRIRHCALSLVGEPIFYPHIDEFLALLHAERISSFLVCNAQHPDQLAALKA VTQLYVSIDASNRESLRKIDRPLHRDFWERFQRCLDILREKRFRHRTVFRLTLVKGFNVDEEVEGYARLVERGLP CFVEVKGVTYCGTSTSANAGISMSNVPFYWEVCDFVRALNSRLADLGLGYGIAAEHAHSCCVLLASERFRVGGVW HTHIDYDRFFDLLEERGPDGDWTPEDYMGAPTPEWALWGNGGFDPRDQRVDRKGRSMEVTVVRERPPEPEPGEGE RT
Coding	>Ophio5\|7035 ATGGAGGCCCTGGGCTGGCATCCGTATTTGTTAACCATCGACGACGTCGTCGACCTCTGGCACGCCCATCGCACG TCCCTCATCCTCGGCACTGTCGCTGTTCTCGTCGCTATACGACTGTTCCTGCGCCGTCACGATGACGACGTGGAG CTCGTTGCGCTGCCTGACGTCTACCGCGACGAGGCTGCGCTGTCTGAAAAGACTAACAGCGGCCCACGGAGAATC AAAGGCGGCGCCGTGAAGAAGGCGGCGGTCAAACGAGAAGCCGACGTCGTCACCGCGATGCCGCCTGTCAAGCTC ATCGTCTTCTTTTCCTCTGTGACGGACACGACTACCAAGTTGGCGCTCGACTATCGGGCTGACTTGGCTGCGGCT ACGGACCAGCTTGCGCGTGAGACGGGACGACCGTTTCTGATACCCGAGGTGTACGACCTTGCTGAGATAGACCTT GACGATTTCTTCATTGCTCCGCCCATGTCTCCCGCTGAGGCCGGTCTATTCTACCTCTTCTTGATTCCGAGCTAC AATGTCGATAGCATCAACGACACTCTCCTGCAACATCTGCGCGAGACGCACCACGACTTTCGTATCGACACGGCG CCTCTCGCCTCGCTTCTGGGCTATTCTGTCTTTGGCTACGGCGACAGGGAGGGTTGGCCGGACGAGGCTCAGGGC TTCTGCTTCCAGGCCATCGAGCTGGACAAGTGCATGTCCAAGCTGACGGGCCGCAAGCGCGCGTATCCCGTGGGA ATGGGCGACGTGAAGAGGCATCATGCCCAGCGGTTCGCTGAGTGGGCTGCCGGTGTTCGGGACGTTGTCGTCGAT GTCGCCCGGACGGGACACCTGGGTCTCGGCGTGCGCGGAAGCGGCAATGCCGTTGAGAGCGACGATGACGATGGT GGCGATGACGGCCAAACGCTTGATCAAGGGGTGGTGCTGGGTGATGTCGAGGATCTGGGCAACATGGTCCGCGCG GGCGGCAGCACGACAAAGGTCAAGCCGCCCCTGGCCGTCGATTTCACCACATATGGCCAGCAGATGCCCGTCGTC AAAGAAATGGTTCCTCGCGGCTCACCCACGTACGCCGCTCTCACCAAACAGGGCTACTCCATCGTCGGCACACAC TCGGGCGTCAAGATCTGCCGATGGACCAAGTCTGCGCTCCGTGGCCGCGGCAGCTGCTACAAGTACTCGCTCTAC GGCATCAACTCGCACCAGTGCATGGAGACGACGCCTTCGCTCTCGTGCTCCAACAAGTGCGTCTTCTGCTGGCGG CACGGCACCAACCCAGTCGGCACGACGTGGCGCTGGGTCGTCGATCCGCCTGACTTGATCCTCCGTGGCGTCAAG GAGGGTCACTATAGCAAGATTCGCATGATGCGTGGCGTGCCAGGCGTGCGCGCTGAGCGGTACGCTGAGGCGTTA CGCATTCGACACTGCGCGCTGTCGCTGGTCGGAGAGCCCATCTTTTACCCTCACATCGACGAGTTTCTCGCCCTG CTGCACGCAGAGCGCATCTCGTCCTTCCTCGTCTGCAATGCCCAGCATCCCGATCAGCTGGCCGCTCTCAAGGCC GTCACGCAGCTGTACGTGTCCATTGACGCGTCCAACCGCGAGTCTCTGCGCAAGATCGACAGGCCGCTCCACCGC GACTTCTGGGAACGCTTCCAGCGGTGTCTGGACATCTTGCGCGAGAAGCGTTTCCGTCACCGCACCGTCTTTCGA CTCACCCTCGTCAAGGGCTTCAACGTTGACGAGGAGGTCGAGGGATATGCCCGTCTGGTGGAACGCGGACTGCCC TGCTTCGTCGAGGTCAAGGGCGTAACCTACTGCGGCACGTCGACGTCGGCCAATGCCGGCATATCCATGTCCAAC GTGCCCTTTTACTGGGAGGTGTGCGACTTCGTCCGCGCCCTGAACTCTCGCCTCGCAGACCTGGGCTTGGGCTAC GGCATCGCAGCCGAGCATGCTCACAGCTGCTGCGTTCTGCTCGCCAGTGAACGGTTCCGCGTCGGCGGCGTGTGG CACACGCACATCGACTACGATCGTTTCTTTGACCTGCTCGAGGAAAGGGGGCCGGATGGGGATTGGACGCCCGAG GATTACATGGGTGCGCCGACGCCCGAGTGGGCGCTGTGGGGGAACGGCGGCTTTGATCCTCGCGATCAGAGGGTA GACCGCAAGGGGCGGAGCATGGAGGTGACGGTCGTTCGGGAGCGGCCACCGGAGCCGGAGCCGGGCGAGGGAGAG AGGACG
Transcript	>Ophio5\|7035 ATGGAGGCCCTGGGCTGGCATCCGTATTTGTTAACCATCGACGACGTCGTCGACCTCTGGCACGCCCATCGCACG TCCCTCATCCTCGGCACTGTCGCTGTTCTCGTCGCTATACGACTGTTCCTGCGCCGTCACGATGACGACGTGGAG CTCGTTGCGCTGCCTGACGTCTACCGCGACGAGGCTGCGCTGTCTGAAAAGACTAACAGCGGCCCACGGAGAATC AAAGGCGGCGCCGTGAAGAAGGCGGCGGTCAAACGAGAAGCCGACGTCGTCACCGCGATGCCGCCTGTCAAGCTC ATCGTCTTCTTTTCCTCTGTGACGGACACGACTACCAAGTTGGCGCTCGACTATCGGGCTGACTTGGCTGCGGCT ACGGACCAGCTTGCGCGTGAGACGGGACGACCGTTTCTGATACCCGAGGTGTACGACCTTGCTGAGATAGACCTT GACGATTTCTTCATTGCTCCGCCCATGTCTCCCGCTGAGGCCGGTCTATTCTACCTCTTCTTGATTCCGAGCTAC AATGTCGATAGCATCAACGACACTCTCCTGCAACATCTGCGCGAGACGCACCACGACTTTCGTATCGACACGGCG CCTCTCGCCTCGCTTCTGGGCTATTCTGTCTTTGGCTACGGCGACAGGGAGGGTTGGCCGGACGAGGCTCAGGGC TTCTGCTTCCAGGCCATCGAGCTGGACAAGTGCATGTCCAAGCTGACGGGCCGCAAGCGCGCGTATCCCGTGGGA ATGGGCGACGTGAAGAGGCATCATGCCCAGCGGTTCGCTGAGTGGGCTGCCGGTGTTCGGGACGTTGTCGTCGAT GTCGCCCGGACGGGACACCTGGGTCTCGGCGTGCGCGGAAGCGGCAATGCCGTTGAGAGCGACGATGACGATGGT GGCGATGACGGCCAAACGCTTGATCAAGGGGTGGTGCTGGGTGATGTCGAGGATCTGGGCAACATGGTCCGCGCG GGCGGCAGCACGACAAAGGTCAAGCCGCCCCTGGCCGTCGATTTCACCACATATGGCCAGCAGATGCCCGTCGTC AAAGAAATGGTTCCTCGCGGCTCACCCACGTACGCCGCTCTCACCAAACAGGGCTACTCCATCGTCGGCACACAC TCGGGCGTCAAGATCTGCCGATGGACCAAGTCTGCGCTCCGTGGCCGCGGCAGCTGCTACAAGTACTCGCTCTAC GGCATCAACTCGCACCAGTGCATGGAGACGACGCCTTCGCTCTCGTGCTCCAACAAGTGCGTCTTCTGCTGGCGG CACGGCACCAACCCAGTCGGCACGACGTGGCGCTGGGTCGTCGATCCGCCTGACTTGATCCTCCGTGGCGTCAAG GAGGGTCACTATAGCAAGATTCGCATGATGCGTGGCGTGCCAGGCGTGCGCGCTGAGCGGTACGCTGAGGCGTTA CGCATTCGACACTGCGCGCTGTCGCTGGTCGGAGAGCCCATCTTTTACCCTCACATCGACGAGTTTCTCGCCCTG CTGCACGCAGAGCGCATCTCGTCCTTCCTCGTCTGCAATGCCCAGCATCCCGATCAGCTGGCCGCTCTCAAGGCC GTCACGCAGCTGTACGTGTCCATTGACGCGTCCAACCGCGAGTCTCTGCGCAAGATCGACAGGCCGCTCCACCGC GACTTCTGGGAACGCTTCCAGCGGTGTCTGGACATCTTGCGCGAGAAGCGTTTCCGTCACCGCACCGTCTTTCGA CTCACCCTCGTCAAGGGCTTCAACGTTGACGAGGAGGTCGAGGGATATGCCCGTCTGGTGGAACGCGGACTGCCC TGCTTCGTCGAGGTCAAGGGCGTAACCTACTGCGGCACGTCGACGTCGGCCAATGCCGGCATATCCATGTCCAAC GTGCCCTTTTACTGGGAGGTGTGCGACTTCGTCCGCGCCCTGAACTCTCGCCTCGCAGACCTGGGCTTGGGCTAC GGCATCGCAGCCGAGCATGCTCACAGCTGCTGCGTTCTGCTCGCCAGTGAACGGTTCCGCGTCGGCGGCGTGTGG CACACGCACATCGACTACGATCGTTTCTTTGACCTGCTCGAGGAAAGGGGGCCGGATGGGGATTGGACGCCCGAG GATTACATGGGTGCGCCGACGCCCGAGTGGGCGCTGTGGGGGAACGGCGGCTTTGATCCTCGCGATCAGAGGGTA GACCGCAAGGGGCGGAGCATGGAGGTGACGGTCGTTCGGGAGCGGCCACCGGAGCCGGAGCCGGGCGAGGGAGAG AGGACGTAG
Gene	>Ophio5\|7035 ATGGAGGCCCTGGGCTGGCATCCGTATTTGTTAACCATCGACGGTGCGGTGAGAACAAGGTGGAGGAGCTGGATT GGATGGATGATGTATAGATAGGCACTCTAGTGAGCCTCTAGTATATAAATGGTTTCTATTCGAGTATAGTCGGGT ATTTATTTATTAAGGGAAAGGCTTTAAGGGGGCAATTATCGTATATCCTCTTCTAGGATCTTCTCCTTCTCTTAG TGGTTATATGTATATAAGCGATAATTCGGTGGGGGTGGTTATGGCCGCTTGCTTTTTTCGACGAGCAAAGCTAGA CGGCAGATGCTCATAGATCCTCACCACGTCCGGCTCGCCTCAGCCAGACCGCCCGGAATGGAGGCCCTGGGCTGG CATCCGTATTTGTTAACCATCGACGGTGCGCAGCCCCAACCCGTCTCCTCTCTCTCACCCGTCGGAGCTGACTCA TGCGACGCCAGACGTCGTCGACCTCTGGCACGCCCATCGCACGTCCCTCATCCTCGGCACTGTCGCTGTTCTCGT CGCTATACGACTGTTCCTGCGCCGTCACGATGACGACGTGGAGCTCGTTGCGCTGCCTGACGTCTACCGCGACGA GGCTGCGCTGTCTGAAAAGACTAACAGCGGCCCACGGAGAATCAAAGGCGGCGCCGTGAAGAAGGCGGCGGTCAA ACGAGAAGCCGACGTCGTCACCGCGATGCCGCCTGTCAAGCTCATCGTCTTCTTTTCCTCTGTGACGGACACGAC TACCAAGTTGGCGCTCGACTATCGGGCTGACTTGGCTGCGGCTACGGACCAGCTTGCGCGTGAGACGGGACGACC GTTTCTGATACCCGAGGTGTACGACCTTGCTGAGATAGACCTTGACGATTTCTTCATTGCTCCGCCCATGTCTCC CGCTGAGGCCGGTCTATTCTACCTCTTCTTGATTCCGAGCTACAATGTCGATAGCATCAACGACACTCTCCTGCA ACATCTGCGCGAGACGCACCACGACTTTCGTATCGACACGGCGCCTCTCGCCTCGCTTCTGGGCTATTCTGTCTT TGGCTACGGCGACAGGGAGGGTTGGCCGGACGAGGCTCAGGGCTTCTGCTTCCAGGCCATCGAGCTGGACAAGTG CATGTCCAAGCTGACGGGCCGCAAGCGCGCGTATCCCGTGGGAATGGGCGACGTGAAGAGGCATCATGCCCAGCG GTTCGCTGAGTGGGCTGCCGGTGTTCGGGACGTTGTCGTCGATGTCGCCCGGACGGGACACCTGGGTCTCGGCGT GCGCGGAAGCGGCAATGCCGTTGAGAGCGACGATGACGATGGTGGCGATGACGGCCAAACGCTTGATCAAGGGGT GGTGCTGGGTGATGTCGAGGATCTGGGCAACATGGTCCGCGCGGGCGGCAGCACGACAAAGGTCAAGCCGCCCCT GGCCGTCGATTTCACCACATATGGCCAGCAGATGCCCGTCGTCAAAGAAATGGTTCCTCGCGGCTCACCCACGTA CGCCGCTCTCACCAAACAGGGCTACTCCATCGTCGGCACACACTCGGGCGTCAAGATCTGCCGATGGACCAAGTC TGCGCTCCGTGGCCGCGGCAGCTGCTACAAGTACTCGCTCTACGGCATCAACTCGCACCAGTGCATGGAGACGAC GCCTTCGCTCTCGTGCTCCAACAAGTGCGTCTTCTGCTGGCGGCACGGCACCAACCCAGTCGGCACGACGTGGCG CTGGGTCGTCGATCCGCCTGACTTGATCCTCCGTGGCGTCAAGGAGGGTCACTATAGCAAGATTCGCATGATGCG TGGCGTGCCAGGCGTGCGCGCTGAGCGGTACGCTGAGGCGTTACGCATTCGACACTGCGCGCTGTCGCTGGTCGG AGAGCCCATCTTTTACCCTCACATCGACGAGTTTCTCGCCCTGCTGCACGCAGAGCGCATCTCGTCCTTCCTCGT CTGCAATGCCCAGCATCCCGATCAGCTGGCCGCTCTCAAGGCCGTCACGCAGCTGTACGTGTCCATTGACGCGTC CAACCGCGAGTCTCTGCGCAAGATCGACAGGCCGCTCCACCGCGACTTCTGGGAACGCTTCCAGCGGTGTCTGGA CATCTTGCGCGAGAAGCGTTTCCGTCACCGCACCGTCTTTCGACTCACCCTCGTCAAGGGCTTCAACGTTGACGA GGAGGTCGAGGGATATGCCCGTCTGGTGGAACGCGGACTGCCCTGCTTCGTCGAGGTCAAGGGCGTAACCTACTG CGGCACGTCGACGTCGGCCAATGCCGGCATATCCATGTCCAACGTGCCCTTTTACTGGGAGGTGTGCGACTTCGT CCGCGCCCTGAACTCTCGCCTCGCAGACCTGGGCTTGGGCTACGGCATCGCAGCCGAGCATGCTCACAGCTGCTG CGTTCTGCTCGCCAGTGAACGGTTCCGCGTCGGCGGCGTGTGGCACACGCACATCGACTACGATCGTTTCTTTGA CCTGCTCGAGGAAAGGGGGCCGGATGGGGATTGGACGCCCGAGGATTACATGGGTGCGCCGACGCCCGAGTGGGC GCTGTGGGGGAACGGCGGCTTTGATCCTCGCGATCAGAGGGTAGACCGCAAGGGGCGGAGCATGGAGGTGACGGT CGTTCGGGAGCGGCCACCGGAGCCGGAGCCGGGCGAGGGAGAGAGGACGTAG

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