Fungal Genomics

at Utrecht University

General Properties

Protein ID	Ophio5\|6417
Gene name
Location	scaffold_56:34622..38452
Strand	-
Gene length (bp)	3830
Transcript length (bp)	3561
Coding sequence length (bp)	3558
Protein length (aa)	1186

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF14500	MMS19_N	Dos2-interacting transcription regulator of RNA-Pol-II	1.1E-48	69	326
PF12460	MMS19_C	RNAPII transcription regulator C-terminal	1.1E-09	881	1093

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|E1BP36\|MMS19_BOVIN	MMS19 nucleotide excision repair protein homolog OS=Bos taurus GN=MMS19 PE=2 SV=3	7	355	5.0E-15
sp\|Q96T76\|MMS19_HUMAN	MMS19 nucleotide excision repair protein homolog OS=Homo sapiens GN=MMS19 PE=1 SV=2	58	355	1.0E-13
sp\|E7FBU4\|MMS19_DANRE	MMS19 nucleotide excision repair protein homolog OS=Danio rerio GN=mms19 PE=3 SV=1	71	355	5.0E-13
sp\|Q9D071\|MMS19_MOUSE	MMS19 nucleotide excision repair protein homolog OS=Mus musculus GN=Mms19 PE=1 SV=1	71	355	2.0E-12
sp\|Q0V9L1\|MMS19_XENTR	MMS19 nucleotide excision repair protein homolog OS=Xenopus tropicalis GN=mms19 PE=2 SV=2	67	423	8.0E-12

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|E1BP36\|MMS19_BOVIN	MMS19 nucleotide excision repair protein homolog OS=Bos taurus GN=MMS19 PE=2 SV=3	7	355	5.0E-15
sp\|Q96T76\|MMS19_HUMAN	MMS19 nucleotide excision repair protein homolog OS=Homo sapiens GN=MMS19 PE=1 SV=2	58	355	1.0E-13
sp\|E7FBU4\|MMS19_DANRE	MMS19 nucleotide excision repair protein homolog OS=Danio rerio GN=mms19 PE=3 SV=1	71	355	5.0E-13
sp\|Q9D071\|MMS19_MOUSE	MMS19 nucleotide excision repair protein homolog OS=Mus musculus GN=Mms19 PE=1 SV=1	71	355	2.0E-12
sp\|Q0V9L1\|MMS19_XENTR	MMS19 nucleotide excision repair protein homolog OS=Xenopus tropicalis GN=mms19 PE=2 SV=2	67	423	8.0E-12
sp\|Q6DCF2\|MMS19_XENLA	MMS19 nucleotide excision repair protein homolog OS=Xenopus laevis GN=mms19 PE=2 SV=1	67	423	1.0E-11
sp\|Q54J88\|MMS19_DICDI	MMS19 nucleotide excision repair protein homolog OS=Dictyostelium discoideum GN=mms19 PE=3 SV=2	187	419	2.0E-10
sp\|P40469\|MET18_YEAST	DNA repair/transcription protein MET18/MMS19 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET18 PE=1 SV=1	135	326	7.0E-07

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 19	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

Click here for more information

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophio5\|6417 MADFRQLALDFILEDDEATLTNIARRAASEIESASLGSNPVARWVEAVQPWMPGSDDDAMRDDGDIPDWTTRAKA LEFLSRTLLLLDQGLLKPSQVNLLVAFFGAMFDVDHKAGIMASATALSRIVTMKSFQPSSGRSIIQMVCALKDDF PRQVAKTRLAIYRLLRSIITDAAVARDLESGGGDGAFMCRLLHLCQNERDPECLMVWLDTLRFFAAEYSSSEAVL DDVYGAFKAYFPITVPRASQSGLTPEELKLQLRRCFSSNGRLAPQTLPFLLEKLDQGDGVTVNVKIDILRTLRAC LEEYAHPQQSVAPFAGRVWDSLKYEVRNGDVEDTVWATLEVLKALTTRLEGDALREFALTVTRECVDDLSSQAYA AAAGRLLISVLSADARAFALMASPAVTHIKENLRHPKSSTHKLDLLKILRILLETRLLLADMQMPDPERQDFGAT DSVFRPLYGDVYRGLVEATDGADASYDVKVTTEAVQGVGALVCQRLSRAAATDEQRTADLLLPQEICAQICDALF SLAARSWELQSPQAASYELINESIKALRRATEAYPLGFQPLMERGLATIRNSYASAVAESVSTIQRVSSVVAFVG CSGLKPSLAHAMRCFLALTCALTWELSAAMDDKRDNRLWCALVAGIETAVHYFKDAFTDVSLEDPLQRPHEDESP SPALWLATIMTRYPLLSSIDSADTPSALDIDTLAIPKVDSAFALRDDFLLVSLVICRHLYRRVTKPLETQGEEAM ALGLGDDFTGADPEVTYRYLSMLSDLASFIVGEMGRSGCPSPQIEAYFLTLFRHDSIALPPVGAVQPPGSWRWLA TGPLSVLSWGILRSMPPVGVARLYDIGVAQRMLLDGTSSAFHGDHAADGLPVTRAILSVLANKYKLETVDGVMTA IEQDAQSALKQAAMGSSPEDQRQGLDQALTIFTLAGSLARRSTGHRTRALLDLLRPAPEDHTAGYRLARGLELVV APQTFLTDSVGSVQRPLWMQKVYVDLVKPMMGAATGTSSVEARSRSIQTNYGIAVLAMVKHMRYPVYEEDSSTII RIAISTAQKLGIGPDTRAALQVINSVLGEAPEVVQDHLGSLISICTSVFTSEPPTTQTDDESPTTQTDDESPEET QAGCAKLALEMVGRLPQTLESRHLLAHAPAVRRQLAAACGHRVRDLRRLARLARTAWADLK
Coding	>Ophio5\|6417 ATGGCCGACTTCCGCCAGCTCGCCCTCGATTTCATCCTGGAGGACGACGAGGCGACGTTGACGAACATCGCCCGC CGCGCGGCATCAGAGATCGAATCTGCCTCCTTGGGCTCCAATCCTGTCGCTCGCTGGGTTGAGGCTGTCCAGCCG TGGATGCCGGGGAGCGACGATGATGCTATGCGCGATGATGGAGATATTCCGGACTGGACCACACGCGCCAAGGCT TTGGAGTTTCTCTCTCGTACCCTGCTTCTCCTAGACCAGGGCCTTTTGAAGCCGAGTCAAGTCAACCTCCTCGTC GCCTTCTTCGGCGCCATGTTCGATGTCGACCACAAGGCCGGCATCATGGCCTCCGCCACGGCCCTTTCGCGCATC GTCACTATGAAGTCATTTCAGCCGTCGAGTGGCCGCAGCATTATCCAGATGGTGTGTGCTCTCAAGGATGACTTT CCTCGTCAAGTGGCAAAGACGCGTTTGGCAATTTACCGTCTTCTTCGTTCCATCATTACCGATGCCGCCGTTGCC CGCGACCTCGAATCCGGCGGGGGTGATGGGGCTTTCATGTGCCGTCTGCTTCATCTCTGCCAGAACGAGAGGGAT CCGGAATGCCTGATGGTGTGGCTCGATACTCTACGCTTCTTCGCGGCCGAATATTCTTCTTCGGAAGCAGTCCTG GACGACGTTTACGGAGCCTTCAAGGCCTACTTTCCCATCACCGTGCCTCGCGCGTCCCAGAGTGGTTTGACGCCC GAGGAGCTCAAGCTTCAATTGCGGCGATGCTTCTCTTCTAACGGCCGTTTGGCTCCTCAAACTTTGCCCTTTCTG CTGGAGAAGCTGGATCAGGGGGACGGTGTGACTGTCAATGTCAAGATTGATATTCTTCGCACACTGAGGGCCTGC CTTGAGGAATACGCTCATCCCCAGCAGTCGGTCGCGCCATTCGCTGGCAGAGTGTGGGATAGCCTCAAGTACGAG GTGCGCAATGGCGACGTTGAGGATACCGTTTGGGCCACTCTCGAGGTGCTCAAGGCGCTCACCACGAGGTTGGAA GGCGACGCGCTGCGAGAGTTCGCCCTGACCGTCACCCGCGAGTGCGTTGACGACCTCTCAAGCCAGGCCTACGCT GCCGCTGCTGGAAGGTTGCTCATCAGTGTATTGAGCGCAGATGCACGTGCCTTTGCTCTCATGGCTTCGCCGGCC GTAACGCACATCAAAGAAAACCTGCGGCATCCCAAGTCGTCGACGCATAAGCTCGATTTGCTCAAGATTCTGCGC ATCCTTCTCGAGACGAGACTGCTCCTCGCAGATATGCAGATGCCAGACCCGGAGAGGCAAGACTTTGGAGCCACA GACTCCGTCTTCCGGCCGCTCTACGGCGACGTCTATCGAGGTCTGGTCGAGGCGACGGATGGAGCAGACGCTTCC TACGACGTTAAAGTGACGACCGAAGCTGTTCAGGGCGTGGGCGCGCTCGTCTGCCAGCGGTTATCGAGGGCGGCG GCCACCGATGAGCAGCGCACCGCAGATCTGCTACTCCCTCAAGAGATATGTGCTCAGATCTGCGACGCGCTCTTC TCCCTTGCAGCCCGGTCCTGGGAGTTGCAGTCGCCGCAGGCCGCATCTTACGAGCTCATCAACGAGAGTATCAAG GCGCTACGACGGGCCACTGAGGCTTATCCTCTGGGCTTCCAGCCATTGATGGAGAGAGGTCTGGCAACGATTCGG AACAGCTACGCCAGCGCCGTCGCCGAGTCTGTCTCTACAATCCAAAGGGTGTCGTCTGTCGTCGCCTTTGTGGGA TGCTCAGGGCTGAAGCCGTCTCTGGCGCACGCCATGAGATGCTTCCTGGCTCTCACATGTGCTTTGACTTGGGAG CTTTCGGCGGCAATGGACGACAAGCGAGATAATCGCCTGTGGTGTGCGTTAGTGGCCGGTATCGAGACGGCCGTT CACTACTTTAAAGATGCCTTTACCGACGTGAGCTTAGAGGATCCCTTACAAAGGCCGCACGAAGACGAGTCGCCG TCGCCGGCCCTTTGGCTGGCAACCATCATGACGAGATACCCCCTATTGAGCTCGATAGATAGCGCCGACACGCCA TCAGCTCTTGACATCGACACGCTGGCGATTCCCAAAGTCGACTCTGCCTTTGCGCTTCGTGACGATTTTCTGCTC GTCAGTCTCGTCATATGCCGCCACCTTTACCGCAGGGTCACAAAGCCGTTGGAGACGCAAGGCGAGGAGGCTATG GCCCTCGGCCTTGGGGATGACTTTACCGGCGCTGACCCGGAAGTTACATATCGCTATCTTTCTATGCTGTCTGAC CTCGCCAGTTTCATCGTGGGAGAGATGGGTCGATCTGGGTGTCCATCGCCGCAGATTGAAGCCTATTTCCTGACT CTATTCCGCCATGACAGCATTGCTCTCCCGCCGGTAGGAGCTGTACAACCTCCTGGCTCGTGGCGCTGGCTGGCT ACGGGACCTTTGAGTGTGCTATCTTGGGGCATTCTTAGGTCTATGCCTCCGGTCGGGGTTGCGCGACTGTACGAT ATTGGTGTCGCTCAGCGAATGCTGCTTGACGGCACCTCGTCTGCTTTCCATGGTGACCACGCTGCGGACGGCCTG CCCGTTACGAGGGCCATTCTATCTGTCCTGGCCAACAAGTACAAGCTCGAGACGGTAGATGGCGTGATGACGGCC ATCGAGCAAGACGCCCAGAGCGCCCTGAAGCAGGCGGCGATGGGATCTAGTCCAGAAGACCAACGACAGGGGCTG GACCAAGCCCTGACCATCTTTACGCTCGCGGGCAGCCTGGCACGGCGGTCTACCGGCCACCGAACACGGGCCTTG CTGGATCTGCTACGGCCGGCGCCCGAAGATCACACGGCGGGCTATCGTCTGGCGAGGGGATTGGAGCTGGTCGTT GCACCCCAGACGTTCCTTACAGACAGCGTCGGATCCGTCCAACGGCCTCTCTGGATGCAGAAAGTCTACGTCGAC CTCGTCAAGCCCATGATGGGTGCCGCCACGGGCACCTCCTCCGTCGAGGCACGGAGCCGGTCGATACAGACAAAC TACGGCATTGCCGTGCTGGCCATGGTCAAGCACATGCGCTACCCCGTCTACGAGGAGGACTCCAGCACCATCATA CGCATAGCCATCTCTACGGCACAGAAACTAGGCATCGGTCCCGACACGAGAGCTGCACTTCAGGTGATCAACAGC GTGCTAGGCGAGGCCCCGGAGGTCGTACAGGATCACCTCGGGAGCCTCATCTCCATCTGCACTAGCGTCTTCACC AGCGAGCCGCCGACGACGCAGACCGACGACGAGTCGCCGACGACGCAAACCGACGACGAGTCGCCGGAAGAGACG CAGGCTGGCTGTGCCAAGCTGGCTCTTGAGATGGTCGGCCGCCTGCCGCAGACGCTGGAGTCGAGACATCTCTTG GCCCATGCGCCTGCGGTGCGGCGACAGCTGGCTGCCGCGTGTGGACACAGGGTTCGGGACCTGAGGAGGTTGGCG CGGCTTGCGCGGACGGCCTGGGCGGACTTGAAG
Transcript	>Ophio5\|6417 ATGGCCGACTTCCGCCAGCTCGCCCTCGATTTCATCCTGGAGGACGACGAGGCGACGTTGACGAACATCGCCCGC CGCGCGGCATCAGAGATCGAATCTGCCTCCTTGGGCTCCAATCCTGTCGCTCGCTGGGTTGAGGCTGTCCAGCCG TGGATGCCGGGGAGCGACGATGATGCTATGCGCGATGATGGAGATATTCCGGACTGGACCACACGCGCCAAGGCT TTGGAGTTTCTCTCTCGTACCCTGCTTCTCCTAGACCAGGGCCTTTTGAAGCCGAGTCAAGTCAACCTCCTCGTC GCCTTCTTCGGCGCCATGTTCGATGTCGACCACAAGGCCGGCATCATGGCCTCCGCCACGGCCCTTTCGCGCATC GTCACTATGAAGTCATTTCAGCCGTCGAGTGGCCGCAGCATTATCCAGATGGTGTGTGCTCTCAAGGATGACTTT CCTCGTCAAGTGGCAAAGACGCGTTTGGCAATTTACCGTCTTCTTCGTTCCATCATTACCGATGCCGCCGTTGCC CGCGACCTCGAATCCGGCGGGGGTGATGGGGCTTTCATGTGCCGTCTGCTTCATCTCTGCCAGAACGAGAGGGAT CCGGAATGCCTGATGGTGTGGCTCGATACTCTACGCTTCTTCGCGGCCGAATATTCTTCTTCGGAAGCAGTCCTG GACGACGTTTACGGAGCCTTCAAGGCCTACTTTCCCATCACCGTGCCTCGCGCGTCCCAGAGTGGTTTGACGCCC GAGGAGCTCAAGCTTCAATTGCGGCGATGCTTCTCTTCTAACGGCCGTTTGGCTCCTCAAACTTTGCCCTTTCTG CTGGAGAAGCTGGATCAGGGGGACGGTGTGACTGTCAATGTCAAGATTGATATTCTTCGCACACTGAGGGCCTGC CTTGAGGAATACGCTCATCCCCAGCAGTCGGTCGCGCCATTCGCTGGCAGAGTGTGGGATAGCCTCAAGTACGAG GTGCGCAATGGCGACGTTGAGGATACCGTTTGGGCCACTCTCGAGGTGCTCAAGGCGCTCACCACGAGGTTGGAA GGCGACGCGCTGCGAGAGTTCGCCCTGACCGTCACCCGCGAGTGCGTTGACGACCTCTCAAGCCAGGCCTACGCT GCCGCTGCTGGAAGGTTGCTCATCAGTGTATTGAGCGCAGATGCACGTGCCTTTGCTCTCATGGCTTCGCCGGCC GTAACGCACATCAAAGAAAACCTGCGGCATCCCAAGTCGTCGACGCATAAGCTCGATTTGCTCAAGATTCTGCGC ATCCTTCTCGAGACGAGACTGCTCCTCGCAGATATGCAGATGCCAGACCCGGAGAGGCAAGACTTTGGAGCCACA GACTCCGTCTTCCGGCCGCTCTACGGCGACGTCTATCGAGGTCTGGTCGAGGCGACGGATGGAGCAGACGCTTCC TACGACGTTAAAGTGACGACCGAAGCTGTTCAGGGCGTGGGCGCGCTCGTCTGCCAGCGGTTATCGAGGGCGGCG GCCACCGATGAGCAGCGCACCGCAGATCTGCTACTCCCTCAAGAGATATGTGCTCAGATCTGCGACGCGCTCTTC TCCCTTGCAGCCCGGTCCTGGGAGTTGCAGTCGCCGCAGGCCGCATCTTACGAGCTCATCAACGAGAGTATCAAG GCGCTACGACGGGCCACTGAGGCTTATCCTCTGGGCTTCCAGCCATTGATGGAGAGAGGTCTGGCAACGATTCGG AACAGCTACGCCAGCGCCGTCGCCGAGTCTGTCTCTACAATCCAAAGGGTGTCGTCTGTCGTCGCCTTTGTGGGA TGCTCAGGGCTGAAGCCGTCTCTGGCGCACGCCATGAGATGCTTCCTGGCTCTCACATGTGCTTTGACTTGGGAG CTTTCGGCGGCAATGGACGACAAGCGAGATAATCGCCTGTGGTGTGCGTTAGTGGCCGGTATCGAGACGGCCGTT CACTACTTTAAAGATGCCTTTACCGACGTGAGCTTAGAGGATCCCTTACAAAGGCCGCACGAAGACGAGTCGCCG TCGCCGGCCCTTTGGCTGGCAACCATCATGACGAGATACCCCCTATTGAGCTCGATAGATAGCGCCGACACGCCA TCAGCTCTTGACATCGACACGCTGGCGATTCCCAAAGTCGACTCTGCCTTTGCGCTTCGTGACGATTTTCTGCTC GTCAGTCTCGTCATATGCCGCCACCTTTACCGCAGGGTCACAAAGCCGTTGGAGACGCAAGGCGAGGAGGCTATG GCCCTCGGCCTTGGGGATGACTTTACCGGCGCTGACCCGGAAGTTACATATCGCTATCTTTCTATGCTGTCTGAC CTCGCCAGTTTCATCGTGGGAGAGATGGGTCGATCTGGGTGTCCATCGCCGCAGATTGAAGCCTATTTCCTGACT CTATTCCGCCATGACAGCATTGCTCTCCCGCCGGTAGGAGCTGTACAACCTCCTGGCTCGTGGCGCTGGCTGGCT ACGGGACCTTTGAGTGTGCTATCTTGGGGCATTCTTAGGTCTATGCCTCCGGTCGGGGTTGCGCGACTGTACGAT ATTGGTGTCGCTCAGCGAATGCTGCTTGACGGCACCTCGTCTGCTTTCCATGGTGACCACGCTGCGGACGGCCTG CCCGTTACGAGGGCCATTCTATCTGTCCTGGCCAACAAGTACAAGCTCGAGACGGTAGATGGCGTGATGACGGCC ATCGAGCAAGACGCCCAGAGCGCCCTGAAGCAGGCGGCGATGGGATCTAGTCCAGAAGACCAACGACAGGGGCTG GACCAAGCCCTGACCATCTTTACGCTCGCGGGCAGCCTGGCACGGCGGTCTACCGGCCACCGAACACGGGCCTTG CTGGATCTGCTACGGCCGGCGCCCGAAGATCACACGGCGGGCTATCGTCTGGCGAGGGGATTGGAGCTGGTCGTT GCACCCCAGACGTTCCTTACAGACAGCGTCGGATCCGTCCAACGGCCTCTCTGGATGCAGAAAGTCTACGTCGAC CTCGTCAAGCCCATGATGGGTGCCGCCACGGGCACCTCCTCCGTCGAGGCACGGAGCCGGTCGATACAGACAAAC TACGGCATTGCCGTGCTGGCCATGGTCAAGCACATGCGCTACCCCGTCTACGAGGAGGACTCCAGCACCATCATA CGCATAGCCATCTCTACGGCACAGAAACTAGGCATCGGTCCCGACACGAGAGCTGCACTTCAGGTGATCAACAGC GTGCTAGGCGAGGCCCCGGAGGTCGTACAGGATCACCTCGGGAGCCTCATCTCCATCTGCACTAGCGTCTTCACC AGCGAGCCGCCGACGACGCAGACCGACGACGAGTCGCCGACGACGCAAACCGACGACGAGTCGCCGGAAGAGACG CAGGCTGGCTGTGCCAAGCTGGCTCTTGAGATGGTCGGCCGCCTGCCGCAGACGCTGGAGTCGAGACATCTCTTG GCCCATGCGCCTGCGGTGCGGCGACAGCTGGCTGCCGCGTGTGGACACAGGGTTCGGGACCTGAGGAGGTTGGCG CGGCTTGCGCGGACGGCCTGGGCGGACTTGAAGTGA
Gene	>Ophio5\|6417 ATGGCCGACTTCCGCCAGCTCGCCCTCGATTTCATCCTGGAGGACGACGAGGCGACGTTGACGAACATCGCCCGC CGCGCGGCATCAGGTCGGCTTCTTCCTCGGTCGCAGTCGATGATTGATGCTTATATATTATCCAGAGATCGAATC TGCCTCCTTGGGCTCCAATCCTGTCGCTCGCTGGGTTGAGGCTGTCCAGCCGTGGATGCCGGGGAGCGACGATGA TGCTATGCGCGATGATGGAGATATTCCGGACTGGACCACACGCGCCAAGGGTAACCTTCTGTATCGCGTCCGCGC TCCGTCACATCTTTCTGACCCGCCCTAGCTTTGGAGTTTCTCTCTCGTACCCTGCTTCTCCTAGACCAGGGCCTT TTGAAGCCGAGTCAAGGTATGTCGAGTCTGGTTCACTTACCAGTCATCAGCCTAATCGCCATAGTCAACCTCCTC GTCGCCTTCTTCGGCGCCATGTTCGATGTCGACCACAAGGCCGGCATCATGGCCTCCGCCACGGCCCTTTCGCGC ATCGTCACTATGAAGTCATTTCAGCCGTCGAGTGGCCGCAGCATTATCCAGATGGTGTGTGCTCTCAAGGATGAC TTTCCTCGTCAAGTGGCAAAGACGCGTTTGGCAATTTACCGTCTTCTTCGTTCCATCATTACCGATGCCGCCGTT GCCCGCGACCTCGAATCCGGCGGGGGTGATGGGGCTTTCATGTGCCGTCTGCTTCATCTCTGCCAGAACGAGAGG GATCCGGAATGCCTGATGGTGTGGCTCGATACTCTACGCTTCTTCGCGGCCGAATATTCTTCTTCGGAAGCAGTC CTGGACGACGTTTACGGAGCCTTCAAGGCCTACTTTCCCATCACCGTGCCTCGCGCGTCCCAGAGTGGTTTGACG CCCGAGGAGCTCAAGCTTCAATTGCGGCGATGCTTCTCTTCTAACGGCCGTTTGGCTCCTCAAACTTTGCCCTTT CTGCTGGAGAAGCTGGATCAGGGGGACGGTGTGACTGTCAATGTCAAGGTATGCCAATCGTCCGACGTAGCCATT TGACCCCCTTCTCACACCTTCCAGATTGATATTCTTCGCACACTGAGGGCCTGCCTTGAGGAATACGCTCATCCC CAGCAGTCGGTCGCGCCATTCGCTGGCAGAGTGTGGGATAGCCTCAAGTACGAGGTGCGCAATGGCGACGTTGAG GATACCGTTTGGGCCACTCTCGAGGTGCTCAAGGCGCTCACCACGAGGTTGGAAGGCGACGCGCTGCGAGAGTTC GCCCTGACCGTCACCCGCGAGTGCGTTGACGACCTCTCAAGCCAGGCCTACGCTGCCGCTGCTGGAAGGTTGCTC ATCAGTGTATTGAGCGCAGATGCACGTGCCTTTGCTCTCATGGCTTCGCCGGCCGTAACGCACATCAAAGAAAAC CTGCGGCATCCCAAGTCGTCGACGCATAAGCTCGATTTGCTCAAGATTCTGCGCATCCTTCTCGAGACGAGACTG CTCCTCGCAGATATGCAGATGCCAGACCCGGAGAGGCAAGACTTTGGAGCCACAGACTCCGTCTTCCGGCCGCTC TACGGCGACGTCTATCGAGGTCTGGTCGAGGCGACGGATGGAGCAGACGCTTCCTACGACGTTAAAGTGACGACC GAAGCTGTTCAGGGCGTGGGCGCGCTCGTCTGCCAGCGGTTATCGAGGGCGGCGGCCACCGATGAGCAGCGCACC GCAGATCTGCTACTCCCTCAAGAGATATGTGCTCAGATCTGCGACGCGCTCTTCTCCCTTGCAGCCCGGTCCTGG GAGTTGCAGTCGCCGCAGGCCGCATCTTACGAGCTCATCAACGAGAGTATCAAGGCGCTACGACGGGCCACTGAG GCTTATCCTCTGGGCTTCCAGCCATTGATGGAGAGAGGTCTGGCAACGATTCGGAACAGCTACGCCAGCGCCGTC GCCGAGTCTGTCTCTACAATCCAAAGGGTGTCGTCTGTCGTCGCCTTTGTGGGATGCTCAGGGCTGAAGCCGTCT CTGGCGCACGCCATGAGATGCTTCCTGGCTCTCACATGTGCTTTGACTTGGGAGCTTTCGGCGGCAATGGACGAC AAGCGAGATAATCGCCTGTGGTGTGCGTTAGTGGCCGGTATCGAGACGGCCGTTCACTACTTTAAAGATGCCTTT ACCGACGTGAGCTTAGAGGATCCCTTACAAAGGCCGCACGAAGACGAGTCGCCGTCGCCGGCCCTTTGGCTGGCA ACCATCATGACGAGATACCCCCTATTGAGCTCGATAGATAGCGCCGACACGCCATCAGCTCTTGACATCGACACG CTGGCGATTCCCAAAGTCGACTCTGCCTTTGCGCTTCGTGACGATTTTCTGCTCGTCAGTCTCGTCATATGCCGC CACCTTTACCGCAGGGTCACAAAGCCGTTGGAGACGCAAGGCGAGGAGGCTATGGCCCTCGGCCTTGGGGATGAC TTTACCGGCGCTGACCCGGAAGTTACATATCGCTATCTTTCTATGCTGTCTGACCTCGCCAGTTTCATCGTGGGA GAGATGGGTCGATCTGGGTGTCCATCGCCGCAGATTGAAGCCTATTTCCTGACTCTATTCCGCCATGACAGCATT GCTCTCCCGCCGGTAGGAGCTGTACAACCTCCTGGCTCGTGGCGCTGGCTGGCTACGGGACCTTTGAGTGTGCTA TCTTGGGGCATTCTTAGGTCTATGCCTCCGGTCGGGGTTGCGCGACTGGTGAGCAATAAATCGCATCTCCAGAGC GTATCTAAAACAGGCAAATGCTGACACAGAGTCGCCAGTACGATATTGGTGTCGCTCAGCGAATGCTGCTTGACG GCACCTCGTCTGCTTTCCATGGTGACCACGCTGCGGACGGCCTGCCCGTTACGAGGGCCATTCTATCTGTCCTGG CCAACAAGTACAAGCTCGAGACGGTAGATGGCGTGATGACGGCCATCGAGCAAGACGCCCAGAGCGCCCTGAAGC AGGCGGCGATGGGATCTAGTCCAGAAGACCAACGACAGGGGCTGGACCAAGCCCTGACCATCTTTACGCTCGCGG GCAGCCTGGCACGGCGGTCTACCGGCCACCGAACACGGGCCTTGCTGGATCTGCTACGGCCGGCGCCCGAAGATC ACACGGCGGGCTATCGTCTGGCGAGGGGATTGGAGCTGGTCGTTGCACCCCAGACGTTCCTTACAGACAGCGTCG GATCCGTCCAACGGCCTCTCTGGATGCAGAAAGTCTACGTCGACCTCGTCAAGCCCATGATGGGTGCCGCCACGG GCACCTCCTCCGTCGAGGCACGGAGCCGGTCGATACAGACAAACTACGGCATTGCCGTGCTGGCCATGGTCAAGC ACATGCGCTACCCCGTCTACGAGGAGGACTCCAGCACCATCATACGCATAGCCATCTCTACGGCACAGAAACTAG GCATCGGTCCCGACACGAGAGCTGCACTTCAGGTGATCAACAGCGTGCTAGGCGAGGCCCCGGAGGTCGTACAGG ATCACCTCGGGAGCCTCATCTCCATCTGCACTAGCGTCTTCACCAGCGAGCCGCCGACGACGCAGACCGACGACG AGTCGCCGACGACGCAAACCGACGACGAGTCGCCGGAAGAGACGCAGGCTGGCTGTGCCAAGCTGGCTCTTGAGA TGGTCGGCCGCCTGCCGCAGACGCTGGAGTCGAGACATCTCTTGGCCCATGCGCCTGCGGTGCGGCGACAGCTGG CTGCCGCGTGTGGACACAGGGTTCGGGACCTGAGGAGGTTGGCGCGGCTTGCGCGGACGGCCTGGGCGGACTTGA AGTGA

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