© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Ophio5|557 |
| Gene name | |
| Location | scaffold_114:38566..41572 |
| Strand | + |
| Gene length (bp) | 3006 |
| Transcript length (bp) | 2613 |
| Coding sequence length (bp) | 2610 |
| Protein length (aa) | 870 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF02366 | PMT | Dolichyl-phosphate-mannose-protein mannosyltransferase | 4.4E-84 | 151 | 399 |
| PF16192 | PMT_4TMC | C-terminal four TMM region of protein-O-mannosyltransferase | 1.3E-67 | 635 | 862 |
| PF02815 | MIR | MIR domain | 1.8E-20 | 446 | 600 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P46971|PMT4_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT4 PE=1 SV=1 | 105 | 870 | 0.0E+00 |
| sp|O42933|PMT4_SCHPO | Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ogm4 PE=3 SV=1 | 117 | 862 | 0.0E+00 |
| sp|Q59X23|PMT4_CANAL | Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT4 PE=2 SV=1 | 117 | 870 | 0.0E+00 |
| sp|Q9Y6A1|POMT1_HUMAN | Protein O-mannosyl-transferase 1 OS=Homo sapiens GN=POMT1 PE=1 SV=3 | 147 | 763 | 1.0E-112 |
| sp|Q99PR0|POMT1_RAT | Protein O-mannosyl-transferase 1 OS=Rattus norvegicus GN=Pomt1 PE=2 SV=1 | 147 | 763 | 1.0E-107 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P46971|PMT4_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT4 PE=1 SV=1 | 105 | 870 | 0.0E+00 |
| sp|O42933|PMT4_SCHPO | Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ogm4 PE=3 SV=1 | 117 | 862 | 0.0E+00 |
| sp|Q59X23|PMT4_CANAL | Dolichyl-phosphate-mannose--protein mannosyltransferase 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT4 PE=2 SV=1 | 117 | 870 | 0.0E+00 |
| sp|Q9Y6A1|POMT1_HUMAN | Protein O-mannosyl-transferase 1 OS=Homo sapiens GN=POMT1 PE=1 SV=3 | 147 | 763 | 1.0E-112 |
| sp|Q99PR0|POMT1_RAT | Protein O-mannosyl-transferase 1 OS=Rattus norvegicus GN=Pomt1 PE=2 SV=1 | 147 | 763 | 1.0E-107 |
| sp|O74189|PMT1_CANAL | Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT1 PE=2 SV=1 | 152 | 780 | 7.0E-105 |
| sp|Q8R2R1|POMT1_MOUSE | Protein O-mannosyl-transferase 1 OS=Mus musculus GN=Pomt1 PE=1 SV=1 | 162 | 763 | 7.0E-104 |
| sp|Q2LZ62|POMT1_DROPS | Protein O-mannosyltransferase 1 OS=Drosophila pseudoobscura pseudoobscura GN=rt PE=3 SV=2 | 154 | 861 | 5.0E-102 |
| sp|Q29IL2|POMT2_DROPS | Protein O-mannosyl-transferase 2 OS=Drosophila pseudoobscura pseudoobscura GN=tw PE=3 SV=1 | 112 | 781 | 6.0E-101 |
| sp|P33775|PMT1_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT1 PE=1 SV=1 | 133 | 782 | 2.0E-100 |
| sp|Q9UKY4|POMT2_HUMAN | Protein O-mannosyl-transferase 2 OS=Homo sapiens GN=POMT2 PE=1 SV=2 | 98 | 850 | 9.0E-100 |
| sp|Q8BGQ4|POMT2_MOUSE | Protein O-mannosyl-transferase 2 OS=Mus musculus GN=Pomt2 PE=1 SV=1 | 88 | 774 | 9.0E-100 |
| sp|Q9W5D4|POMT2_DROME | Protein O-mannosyl-transferase 2 OS=Drosophila melanogaster GN=tw PE=2 SV=1 | 113 | 779 | 4.0E-97 |
| sp|Q9VTK2|POMT1_DROME | Protein O-mannosyltransferase 1 OS=Drosophila melanogaster GN=rt PE=2 SV=2 | 123 | 861 | 5.0E-97 |
| sp|Q9C100|PMT2_SCHPO | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ogm2 PE=3 SV=1 | 101 | 777 | 1.0E-92 |
| sp|P52867|PMT5_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT5 PE=1 SV=1 | 122 | 780 | 6.0E-92 |
| sp|P31382|PMT2_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT2 PE=1 SV=2 | 101 | 772 | 1.0E-90 |
| sp|Q5ACU3|PMT5_CANAL | Dolichyl-phosphate-mannose--protein mannosyltransferase 5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT5 PE=2 SV=1 | 135 | 763 | 8.0E-83 |
| sp|P42934|PMT6_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT6 PE=1 SV=1 | 103 | 783 | 2.0E-82 |
| sp|Q5ADM9|PMT2_CANAL | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT2 PE=1 SV=1 | 120 | 787 | 3.0E-82 |
| sp|P47190|PMT3_YEAST | Dolichyl-phosphate-mannose--protein mannosyltransferase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT3 PE=1 SV=2 | 150 | 763 | 4.0E-82 |
| sp|Q5A688|PMT6_CANAL | Dolichyl-phosphate-mannose--protein mannosyltransferase 6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PMT6 PE=2 SV=1 | 146 | 780 | 5.0E-68 |
| sp|O13898|PMT1_SCHPO | Dolichyl-phosphate-mannose--protein mannosyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ogm1 PE=1 SV=1 | 147 | 763 | 4.0E-58 |
| sp|Q93ZE8|SDF2_ARATH | Stromal cell-derived factor 2-like protein OS=Arabidopsis thaliana GN=SDF2 PE=1 SV=1 | 425 | 612 | 7.0E-10 |
| sp|Q06644|PMT7_YEAST | Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PMT7 PE=1 SV=1 | 149 | 595 | 2.0E-07 |
| sp|Q8NRZ6|PMT_CORGL | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) GN=pmt PE=3 SV=1 | 151 | 397 | 5.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0006493 | protein O-linked glycosylation | Yes |
| GO:0000030 | mannosyltransferase activity | Yes |
| GO:0016020 | membrane | Yes |
| GO:0016740 | transferase activity | No |
| GO:0043170 | macromolecule metabolic process | No |
| GO:0008150 | biological_process | No |
| GO:1901564 | organonitrogen compound metabolic process | No |
| GO:0006486 | protein glycosylation | No |
| GO:0044238 | primary metabolic process | No |
| GO:0043412 | macromolecule modification | No |
| GO:0070085 | glycosylation | No |
| GO:0008152 | metabolic process | No |
| GO:0003674 | molecular_function | No |
| GO:0016758 | hexosyltransferase activity | No |
| GO:0043413 | macromolecule glycosylation | No |
| GO:0071704 | organic substance metabolic process | No |
| GO:0110165 | cellular anatomical entity | No |
| GO:0019538 | protein metabolic process | No |
| GO:0005575 | cellular_component | No |
| GO:0036211 | protein modification process | No |
| GO:0016757 | glycosyltransferase activity | No |
| GO:0006807 | nitrogen compound metabolic process | No |
| GO:0003824 | catalytic activity | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 22 | 0.45 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 145 | 164 | 19 |
| 2 | 189 | 211 | 22 |
| 3 | 232 | 254 | 22 |
| 4 | 258 | 275 | 17 |
| 5 | 282 | 304 | 22 |
| 6 | 334 | 356 | 22 |
| 7 | 377 | 399 | 22 |
| 8 | 691 | 710 | 19 |
| 9 | 730 | 752 | 22 |
| 10 | 757 | 779 | 22 |
| 11 | 820 | 842 | 22 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Ophio5|557 MGHRRVSFISSTPALATDARGSKAGTSGHACSLTIAHQLPRAAPVGPAAKEPRGQRPEAAHSAIPAWQYRRLHPV TLFPLSAVVSLDFLRRVIMPSSPPPQGGLRHRNVGFKKPGDSPRQALEEELDKLSKVTIRKTVAEGERGHAVSLV LITLLAFITRFWGISHPNEVVFDEVHFGKFASYYLERTYFFDVHPPFAKLLFAFMGWLVGYDGHFHFENIGDSYI ANQVPYVAFRALPAILGALTVSVTYLIMWESGYSIPACIIAAGLVLLDNAHIGQTRLILLDATLVFAMACSLLCY IKFYKLRHQPFSRKWWKWLILTGFALSCDISTKYVGLFAFVTIGSAVAIDLWDLLNIKRPGGAISLVEFGKHFAA RAFGLIFLPFLFYLFWFQVHFAVLSRSGPGDDFMTPQFQETLSDNVMLAQSIDINYYDAITIRHKETKTYLHSHD DRYPLRYDDGRVSSQGQQVTGYPHNDTNNYWQILPLDDNKELDKRVKNHHLVRLRHMATDKMLLSHDVASPYYPT NQEFTCVSLEEAYGSRANDTVFEIRIEHGKDNQDFKSVASHFKLIHNPSKVAMWTHTKPLPEWGHRQQEINGNKN IAPSSNVWFVEEVPSLTAEDKRRDKPEREVKTMPFISKWLELQRAMFYHNNKLTSSHPYASHPYQWPFLFRGVSF WTHGETRQQIYFVGNLVGWWLASGVLCVFAGIILADQVSLRRGVDSLDHRTRSRLYNSTGFFWLAWATHYFPFFL MGRQLFLHHYLPAHLASCLVTGALVEFVFTSEHTEPEDRERHRAVKGGKKTVEGPKRHITARERLAGQSMAGIWI ASIVIVFVATASWYFFLPLTYGYPGLSIEQVLQRKWLGFDLHFAK |
| Coding | >Ophio5|557 ATGGGACACAGACGCGTCTCCTTTATTAGCTCGACGCCTGCGTTGGCCACGGATGCTCGCGGCTCGAAGGCGGGA ACATCTGGACACGCCTGCAGCTTGACGATTGCCCACCAGCTCCCACGGGCAGCTCCAGTGGGTCCAGCCGCCAAG GAGCCCCGCGGACAGCGCCCAGAGGCCGCCCACAGCGCCATTCCCGCCTGGCAATATAGGCGGTTACATCCTGTT ACTCTCTTCCCTTTGTCCGCAGTCGTGTCGCTTGATTTCTTGCGTCGCGTGATTATGCCTTCCAGCCCGCCGCCG CAGGGTGGCCTGCGGCATCGAAACGTCGGGTTCAAGAAGCCTGGTGACTCGCCCCGCCAGGCTCTCGAGGAGGAG CTCGACAAGCTTTCCAAGGTCACGATACGCAAGACGGTCGCAGAAGGCGAGCGCGGACATGCCGTCTCTCTCGTC CTCATCACCCTGCTAGCCTTTATCACCCGCTTCTGGGGCATCAGTCACCCCAATGAAGTCGTGTTCGACGAGGTG CATTTCGGAAAGTTTGCCTCGTACTACCTCGAACGCACCTACTTTTTCGACGTTCACCCGCCCTTCGCGAAGCTG TTGTTTGCCTTTATGGGATGGCTCGTCGGCTACGATGGGCATTTTCACTTCGAGAACATCGGTGACTCGTACATC GCCAACCAAGTCCCCTACGTGGCTTTTCGGGCTCTTCCCGCCATCCTTGGCGCCCTCACCGTGTCGGTCACGTAT CTCATCATGTGGGAGTCTGGCTACAGCATCCCCGCCTGCATCATAGCCGCGGGATTGGTTCTGTTGGATAATGCT CACATTGGCCAGACTCGTCTCATCCTCCTCGACGCGACCCTCGTTTTCGCCATGGCCTGTAGCCTTCTGTGCTAC ATCAAGTTCTACAAGCTGCGCCACCAGCCATTCAGCAGGAAGTGGTGGAAGTGGCTGATCCTGACCGGCTTCGCC CTTTCCTGCGACATATCCACAAAGTACGTGGGATTGTTCGCCTTTGTCACCATCGGGTCCGCAGTGGCTATCGAC CTCTGGGACCTGCTGAACATCAAGAGGCCTGGAGGTGCCATCAGTCTCGTCGAGTTTGGCAAGCATTTCGCGGCT CGCGCGTTCGGTCTCATCTTCCTACCCTTCCTCTTCTACCTGTTCTGGTTCCAGGTCCACTTCGCCGTCCTGTCA CGCTCGGGCCCCGGCGACGACTTTATGACACCCCAGTTCCAGGAAACGCTGAGTGACAACGTCATGTTGGCGCAG TCCATCGACATCAATTACTACGACGCCATCACCATCAGGCACAAGGAGACCAAGACCTATCTCCACAGCCACGAC GACCGCTACCCCCTGAGGTACGATGACGGCCGTGTTTCCAGTCAGGGTCAGCAGGTGACCGGTTACCCCCACAAC GACACCAACAACTATTGGCAAATTCTTCCTCTGGACGACAACAAGGAGCTTGACAAGAGGGTCAAGAACCATCAC CTGGTGCGGCTCAGGCACATGGCCACCGACAAGATGCTCCTTTCCCACGACGTTGCGTCTCCTTACTATCCCACC AACCAGGAGTTCACTTGCGTATCGCTCGAGGAAGCGTACGGCAGTCGCGCCAACGACACCGTCTTCGAGATCCGC ATCGAGCATGGCAAGGACAACCAGGACTTCAAATCCGTCGCCAGCCACTTTAAGCTGATTCACAACCCGAGCAAG GTCGCCATGTGGACTCACACCAAGCCCCTTCCCGAGTGGGGGCACCGGCAACAGGAGATTAATGGCAACAAAAAC ATCGCCCCAAGCTCCAACGTCTGGTTTGTCGAGGAGGTTCCCTCGCTTACTGCCGAGGACAAGCGACGCGACAAG CCGGAGCGCGAGGTCAAGACGATGCCCTTCATAAGCAAGTGGCTCGAGCTACAGAGGGCCATGTTCTATCACAAC AACAAGCTGACAAGCAGCCACCCCTATGCCAGTCACCCATACCAGTGGCCTTTTCTCTTCCGCGGCGTGAGCTTC TGGACCCATGGTGAAACCCGTCAGCAGATCTACTTCGTCGGCAACCTGGTGGGCTGGTGGCTCGCCAGCGGCGTC CTGTGCGTCTTCGCTGGCATCATCCTTGCCGATCAGGTGTCTCTGAGGCGTGGAGTGGATTCTCTGGATCATCGC ACTCGCTCCCGGCTCTACAATTCGACGGGCTTCTTCTGGTTGGCATGGGCCACGCACTACTTCCCCTTCTTCCTG ATGGGCCGACAGCTCTTCCTGCACCACTACCTTCCGGCGCATCTGGCCTCGTGTCTGGTCACGGGCGCGCTTGTC GAATTTGTCTTCACCTCGGAACACACCGAGCCTGAAGACAGAGAGCGCCACCGGGCCGTCAAAGGCGGGAAGAAG ACGGTCGAGGGGCCAAAGCGGCACATTACTGCTCGCGAGAGGCTCGCTGGCCAGAGCATGGCGGGCATCTGGATC GCGAGCATCGTGATAGTGTTTGTGGCTACAGCGAGTTGGTATTTCTTCCTGCCCCTGACCTACGGCTATCCCGGG TTGTCGATCGAGCAAGTCTTGCAGCGCAAATGGCTGGGTTTCGACCTTCATTTCGCCAAG |
| Transcript | >Ophio5|557 ATGGGACACAGACGCGTCTCCTTTATTAGCTCGACGCCTGCGTTGGCCACGGATGCTCGCGGCTCGAAGGCGGGA ACATCTGGACACGCCTGCAGCTTGACGATTGCCCACCAGCTCCCACGGGCAGCTCCAGTGGGTCCAGCCGCCAAG GAGCCCCGCGGACAGCGCCCAGAGGCCGCCCACAGCGCCATTCCCGCCTGGCAATATAGGCGGTTACATCCTGTT ACTCTCTTCCCTTTGTCCGCAGTCGTGTCGCTTGATTTCTTGCGTCGCGTGATTATGCCTTCCAGCCCGCCGCCG CAGGGTGGCCTGCGGCATCGAAACGTCGGGTTCAAGAAGCCTGGTGACTCGCCCCGCCAGGCTCTCGAGGAGGAG CTCGACAAGCTTTCCAAGGTCACGATACGCAAGACGGTCGCAGAAGGCGAGCGCGGACATGCCGTCTCTCTCGTC CTCATCACCCTGCTAGCCTTTATCACCCGCTTCTGGGGCATCAGTCACCCCAATGAAGTCGTGTTCGACGAGGTG CATTTCGGAAAGTTTGCCTCGTACTACCTCGAACGCACCTACTTTTTCGACGTTCACCCGCCCTTCGCGAAGCTG TTGTTTGCCTTTATGGGATGGCTCGTCGGCTACGATGGGCATTTTCACTTCGAGAACATCGGTGACTCGTACATC GCCAACCAAGTCCCCTACGTGGCTTTTCGGGCTCTTCCCGCCATCCTTGGCGCCCTCACCGTGTCGGTCACGTAT CTCATCATGTGGGAGTCTGGCTACAGCATCCCCGCCTGCATCATAGCCGCGGGATTGGTTCTGTTGGATAATGCT CACATTGGCCAGACTCGTCTCATCCTCCTCGACGCGACCCTCGTTTTCGCCATGGCCTGTAGCCTTCTGTGCTAC ATCAAGTTCTACAAGCTGCGCCACCAGCCATTCAGCAGGAAGTGGTGGAAGTGGCTGATCCTGACCGGCTTCGCC CTTTCCTGCGACATATCCACAAAGTACGTGGGATTGTTCGCCTTTGTCACCATCGGGTCCGCAGTGGCTATCGAC CTCTGGGACCTGCTGAACATCAAGAGGCCTGGAGGTGCCATCAGTCTCGTCGAGTTTGGCAAGCATTTCGCGGCT CGCGCGTTCGGTCTCATCTTCCTACCCTTCCTCTTCTACCTGTTCTGGTTCCAGGTCCACTTCGCCGTCCTGTCA CGCTCGGGCCCCGGCGACGACTTTATGACACCCCAGTTCCAGGAAACGCTGAGTGACAACGTCATGTTGGCGCAG TCCATCGACATCAATTACTACGACGCCATCACCATCAGGCACAAGGAGACCAAGACCTATCTCCACAGCCACGAC GACCGCTACCCCCTGAGGTACGATGACGGCCGTGTTTCCAGTCAGGGTCAGCAGGTGACCGGTTACCCCCACAAC GACACCAACAACTATTGGCAAATTCTTCCTCTGGACGACAACAAGGAGCTTGACAAGAGGGTCAAGAACCATCAC CTGGTGCGGCTCAGGCACATGGCCACCGACAAGATGCTCCTTTCCCACGACGTTGCGTCTCCTTACTATCCCACC AACCAGGAGTTCACTTGCGTATCGCTCGAGGAAGCGTACGGCAGTCGCGCCAACGACACCGTCTTCGAGATCCGC ATCGAGCATGGCAAGGACAACCAGGACTTCAAATCCGTCGCCAGCCACTTTAAGCTGATTCACAACCCGAGCAAG GTCGCCATGTGGACTCACACCAAGCCCCTTCCCGAGTGGGGGCACCGGCAACAGGAGATTAATGGCAACAAAAAC ATCGCCCCAAGCTCCAACGTCTGGTTTGTCGAGGAGGTTCCCTCGCTTACTGCCGAGGACAAGCGACGCGACAAG CCGGAGCGCGAGGTCAAGACGATGCCCTTCATAAGCAAGTGGCTCGAGCTACAGAGGGCCATGTTCTATCACAAC AACAAGCTGACAAGCAGCCACCCCTATGCCAGTCACCCATACCAGTGGCCTTTTCTCTTCCGCGGCGTGAGCTTC TGGACCCATGGTGAAACCCGTCAGCAGATCTACTTCGTCGGCAACCTGGTGGGCTGGTGGCTCGCCAGCGGCGTC CTGTGCGTCTTCGCTGGCATCATCCTTGCCGATCAGGTGTCTCTGAGGCGTGGAGTGGATTCTCTGGATCATCGC ACTCGCTCCCGGCTCTACAATTCGACGGGCTTCTTCTGGTTGGCATGGGCCACGCACTACTTCCCCTTCTTCCTG ATGGGCCGACAGCTCTTCCTGCACCACTACCTTCCGGCGCATCTGGCCTCGTGTCTGGTCACGGGCGCGCTTGTC GAATTTGTCTTCACCTCGGAACACACCGAGCCTGAAGACAGAGAGCGCCACCGGGCCGTCAAAGGCGGGAAGAAG ACGGTCGAGGGGCCAAAGCGGCACATTACTGCTCGCGAGAGGCTCGCTGGCCAGAGCATGGCGGGCATCTGGATC GCGAGCATCGTGATAGTGTTTGTGGCTACAGCGAGTTGGTATTTCTTCCTGCCCCTGACCTACGGCTATCCCGGG TTGTCGATCGAGCAAGTCTTGCAGCGCAAATGGCTGGGTTTCGACCTTCATTTCGCCAAGTGA |
| Gene | >Ophio5|557 ATGGGACACAGACGCGTCTCCTTTATTAGCTCGACGCCTGCGTTGGCCACGGATGCTCGCGGCTCGAAGGCGGGA ACATCTGGACACGCCTGCAGCTTGACGATTGCCCACCAGCTCCCACGGGCAGCTCCAGTGGGTCCAGCCGCCAAG GAGCCCCGCGGACAGCGCCCAGAGGCCGCCCACAGCGCCATTCCCGCCTGGCAATATAGGCGGGTAGTTCCAATT TTTTTTTTTCACCCCTACCCGCAGCGCACCAACGGTGACATTGACTGAATCAATATCAATCCCATCCGTTTCCCA TCTTCTAACCGTCAAAGTTACATCCTGTTACTCTCTTCCCTTTGTCCGCAGTCGTGTCGCTTGATTTCTTGCGTC GCGTGGTAAGTGAACTTGTCTTCCCTCTCCACTCCCCCCTTTTTGCCCCTTGTCCTAATCGCGTGGCTTCAATTC TCCGCTCCCCAAAGCTTCCCTGTCCCCTCCCCCGGGGGATCACTTCTCTCCCTCGTTCCCTTCCTTCGACTTCTC AAGACGACTGTTGACACGTCAATCACGCCGCATCTCTAGATTATGCCTTCCAGCCCGCCGCCGCAGGGTGGCCTG CGGCATCGAAACGTCGGGTTCAAGAAGCCTGGTGACTCGCCCCGCCAGGCTCTCGAGGAGGAGCTCGACAAGCTT TCCAAGGTCACGATACGCAAGACGGTCGCAGAAGGCGAGCGCGGACATGCCGTCTCTCTCGTCCTCATCACCCTG CTAGCCTTTATCACCCGCTTCTGGGGCATCAGTCACCCCAATGAAGTCGTGTTCGACGAGGTGCATTTCGGAAAG GTGCGTCTCCAAGCCCGTCGCGTGCCTCCAGCTGCTGACTTGGGACTCGTCTGCAGTTTGCCTCGTACTACCTCG AACGCACCTACTTTTTCGACGTTCACCCGCCCTTCGCGAAGCTGTTGTTTGCCTTTATGGGATGGCTCGTCGGCT ACGATGGGCATTTTCACTTCGAGAACATCGGTGACTCGTACATCGCCAACCAAGTCCCCTACGTGGCTTTTCGGG CTCTTCCCGCCATCCTTGGCGCCCTCACCGTGTCGGTCACGTATCTCATCATGTGGGAGTCTGGCTACAGCATCC CCGCCTGCATCATAGCCGCGGGATTGGTTCTGTTGGATAATGCTCACATTGGCCAGACTCGTCTCATCCTCCTCG ACGCGACCCTCGTTTTCGCCATGGCCTGTAGCCTTCTGTGCTACATCAAGTTCTACAAGCTGCGCCACCAGCCAT TCAGCAGGAAGTGGTGGAAGTGGCTGATCCTGACCGGCTTCGCCCTTTCCTGCGACATATCCACAAAGTACGTGG GATTGTTCGCCTTTGTCACCATCGGGTCCGCAGTGGCTATCGACCTCTGGGACCTGCTGAACATCAAGAGGCCTG GAGGTGCCATCAGTCTCGTCGAGTTTGGCAAGCATTTCGCGGCTCGCGCGTTCGGTCTCATCTTCCTACCCTTCC TCTTCTACCTGTTCTGGTTCCAGGTCCACTTCGCCGTCCTGTCACGCTCGGGCCCCGGCGACGACTTTATGACAC CCCAGTTCCAGGAAACGCTGAGTGACAACGTCATGTTGGCGCAGTCCATCGACATCAATTACTACGACGCCATCA CCATCAGGCACAAGGAGACCAAGACCTATCTCCACAGCCACGACGACCGCTACCCCCTGAGGTACGATGACGGCC GTGTTTCCAGTCAGGGTCAGCAGGTGACCGGTTACCCCCACAACGACACCAACAACTATTGGCAAATTCTTCCTC TGGACGACAACAAGGAGCTTGACAAGAGGGTCAAGAACCATCACCTGGTGCGGCTCAGGCACATGGCCACCGACA AGATGCTCCTTTCCCACGACGTTGCGTCTCCTTACTATCCCACCAACCAGGAGTTCACTTGCGTATCGCTCGAGG AAGCGTACGGCAGTCGCGCCAACGACACCGTCTTCGAGATCCGCATCGAGCATGGCAAGGACAACCAGGACTTCA AATCCGTCGCCAGCCACTTTAAGCTGATTCACAACCCGAGCAAGGTCGCCATGTGGACTCACACCAAGCCCCTTC CCGAGTGGGGGCACCGGCAACAGGAGATTAATGGCAACAAAAACATCGCCCCAAGCTCCAACGTCTGGTTTGTCG AGGAGGTTCCCTCGCTTACTGCCGAGGACAAGCGACGCGACAAGCCGGAGCGCGAGGTCAAGACGATGCCCTTCA TAAGCAAGTGGCTCGAGCTACAGAGGGCCATGTTCTATCACAACAACAAGCTGACAAGCAGCCACCCCTATGCCA GTCACCCATACCAGTGGCCTTTTCTCTTCCGCGGCGTGAGCTTCTGGACCCATGGTGAAACCCGTCAGCAGATCT ACTTCGTCGGCAACCTGGTGGGCTGGTGGCTCGCCAGCGGCGTCCTGTGCGTCTTCGCTGGCATCATCCTTGCCG ATCAGGTGTCTCTGAGGCGTGGAGTGGATTCTCTGGATCATCGTGAGTGCTCCAGCCCATTTCCCCCGACGGTAA ACTAATGTCGGCACAGGCACTCGCTCCCGGCTCTACAATTCGACGGGCTTCTTCTGGTTGGCATGGGCCACGCAC TACTTCCCCTTCTTCCTGATGGGCCGACAGCTCTTCCTGCACCACTACCTTCCGGCGCATCTGGCCTCGTGTCTG GTCACGGGCGCGCTTGTCGAATTTGTCTTCACCTCGGAACACACCGAGCCTGAAGACAGAGAGCGCCACCGGGCC GTCAAAGGCGGGAAGAAGACGGTCGAGGGGCCAAAGCGGCACATTACTGCTCGCGAGAGGCTCGCTGGCCAGAGC ATGGCGGGCATCTGGATCGCGAGCATCGTGATAGTGTTTGTGGCTACAGCGAGTTGGTATTTCTTCCTGCCCCTG ACCTACGGCTATCCCGGGTTGTCGATCGAGCAAGTCTTGCAGCGCAAATGGCTGGGTTTCGACCTTCATTTCGCC AAGTGA |