Fungal Genomics

at Utrecht University

General Properties

Protein IDOphio5|5340
Gene name
Locationscaffold_434:3346..7179
Strand+
Gene length (bp)3833
Transcript length (bp)3168
Coding sequence length (bp)3165
Protein length (aa) 1055

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PFAM Domains

PFAM Domain ID Short name Long name E-value Start End
PF12349 Sterol-sensing Sterol-sensing domain of SREBP cleavage-activation 7.0E-35 266 407
PF02460 Patched Patched family 2.9E-12 252 401

Swissprot hits

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Swissprot ID Swissprot Description Start End E-value
sp|A2RRU4|SCAP_RAT Sterol regulatory element-binding protein cleavage-activating protein OS=Rattus norvegicus GN=Scap PE=2 SV=1 220 408 2.0E-18
sp|P97260|SCAP_CRIGR Sterol regulatory element-binding protein cleavage-activating protein OS=Cricetulus griseus GN=SCAP PE=1 SV=1 220 408 2.0E-18
sp|Q6GQT6|SCAP_MOUSE Sterol regulatory element-binding protein cleavage-activating protein OS=Mus musculus GN=Scap PE=1 SV=1 220 408 3.0E-18
sp|Q5MNU5|SCAP_PIG Sterol regulatory element-binding protein cleavage-activating protein OS=Sus scrofa GN=SCAP PE=2 SV=2 220 408 4.0E-18
sp|A0JPH4|SCAP_XENLA Sterol regulatory element-binding protein cleavage-activating protein OS=Xenopus laevis GN=scap PE=2 SV=1 221 428 5.0E-18
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Swissprot ID Swissprot Description Start End E-value
sp|A2RRU4|SCAP_RAT Sterol regulatory element-binding protein cleavage-activating protein OS=Rattus norvegicus GN=Scap PE=2 SV=1 220 408 2.0E-18
sp|P97260|SCAP_CRIGR Sterol regulatory element-binding protein cleavage-activating protein OS=Cricetulus griseus GN=SCAP PE=1 SV=1 220 408 2.0E-18
sp|Q6GQT6|SCAP_MOUSE Sterol regulatory element-binding protein cleavage-activating protein OS=Mus musculus GN=Scap PE=1 SV=1 220 408 3.0E-18
sp|Q5MNU5|SCAP_PIG Sterol regulatory element-binding protein cleavage-activating protein OS=Sus scrofa GN=SCAP PE=2 SV=2 220 408 4.0E-18
sp|A0JPH4|SCAP_XENLA Sterol regulatory element-binding protein cleavage-activating protein OS=Xenopus laevis GN=scap PE=2 SV=1 221 428 5.0E-18
sp|Q12770|SCAP_HUMAN Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP PE=1 SV=4 220 408 5.0E-18
sp|O43043|SCAP_SCHPO Sterol regulatory element-binding protein cleavage-activating protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=scp1 PE=1 SV=1 245 684 6.0E-18
sp|A6QM06|SCAP_BOVIN Sterol regulatory element-binding protein cleavage-activating protein OS=Bos taurus GN=SCAP PE=2 SV=1 220 408 7.0E-18
sp|Q0EEE2|PTHD3_MOUSE Patched domain-containing protein 3 OS=Mus musculus GN=Ptchd3 PE=1 SV=1 192 403 8.0E-09
sp|P56941|NPC1_PIG Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1 173 405 5.0E-08
sp|O15118|NPC1_HUMAN Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2 238 405 2.0E-07
sp|O35604|NPC1_MOUSE Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=2 238 405 9.0E-07
sp|O35595|PTC2_MOUSE Protein patched homolog 2 OS=Mus musculus GN=Ptch2 PE=2 SV=2 192 403 4.0E-06
sp|Q3KNS1|PTHD3_HUMAN Patched domain-containing protein 3 OS=Homo sapiens GN=PTCHD3 PE=1 SV=3 198 403 9.0E-06
sp|Q13635|PTC1_HUMAN Protein patched homolog 1 OS=Homo sapiens GN=PTCH1 PE=1 SV=2 238 405 9.0E-06
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GO

GO Term Description Terminal node
GO:0016021 integral component of membrane Yes
GO:0110165 cellular anatomical entity No
GO:0005575 cellular_component No
GO:0031224 intrinsic component of membrane No

SignalP

[Help with interpreting these statistics]
SignalP signal predicted Location
(based on Ymax)		 D score
(significance: > 0.45)
No 1 - 18 0.5

Transmembrane Domains

Domain # Start End Length
1 39 61 22
2 132 151 19
3 242 259 17
4 274 296 22
5 308 330 22
6 345 367 22
7 374 396 22
8 446 465 19
9 568 590 22

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

Expression values

Label Description Expression (RPKM) Confidence interval (low) Confidence interval (high)
SC16a Pure fungal culture 99.18 48.78 149.59
CcL In ants, during behavior modification 31.41 17.08 45.75
CcD In ants, recently dead 51.01 27.19 74.84

Differential expression

Label1 Label2 Q-value Significant difference
SC16a CcL 0.000286 yes
SC16a CcD 0.004639 yes
CcL CcD 0.027948 yes

Sequences

Type of sequenceSequence
Locus Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein >Ophio5|5340
MIWYLLYPLRGTTEAPALPSSHPLYNAFARYGRYAARHVVATLLVSAAVATVLVYPIPFLFTSDFVNGASNLPRH
VWTVAQPLLYNTAAEPDIIMRSIWVHASYMQALNTELLVSALNLQDDLLGITKNFSPASARLLVLSFAFTVLGLL
SKNQSTFANVTLRHSIVFSGKRFEERRLLAADSLVITLLHLRDSPVGRRWESRILELPQKVGNTWNIYPPDGRAA
SSQLYEFQFRPISMQDIASLALAYGLTLVYFLTSLSKLRAVKSKVGLIVTVLAQIVFSIMSSFTVCAVFNVDLSR
IPRAAYPLVVLAMSLEHIFRLINAVILTPLEDIVSNRIGQAFAETAPTAMFSTLQNVIILAGLSRLVSAGVSGFC
VFAAIAIVFDFFYLSTFFLAVLSVDVRRMELGDALAKASMRHNRNKPDTGVSRRWWWDPVLQGRIAMSTRIAGTI
VMVGFVLIAQWHFFSDEGSFRKLVRFYRDLDRDQGPGHSRSSLLDSVHQARSPTSWLRIQDHETAREVINIIKPS
SYSYVARVYDPIVFVLKNSDRVPHSKEPALLPAVYDFVNHELVRFVVVVVVVIAALRLLTSFLLWEDENLNDQHE
PDELPRLSVRSLARGHLMDVVLLTTSADGHVVSAGLDNTIRAWSIHGVGTSYVIAKGDESEMAVFPVVAMAIDDD
SKWLALLSRPKRSACSRVSFWDLQSRAWGSSIQADNRRHRPVALLFDPSAPSHQPRALVVQQDGSLSELLSGEKK
ERQFVSMFPPHLTCARLLARKEGGPQPIILAVSRQGEVHMAARDQGVWRSRRLAIGGLGEPGAHSIQVVAPLNLF
VVAAGDRAHLIDGKDGGVLQTLRTAAMLPRPLRCAYKRHPSSQLESMGLASFTLGYVEADSRDCILQTYMPPEDC
DAIYLQTPCEAWSSNWCTWESARETRKRVADPGVWEMVSDGSAVGIRFSAPGGKGLQMSGLRNRYGKRVPEPDPL
EGWQVWMESLPGCRPEESESRRLIKDGEQAGHLLVTEVGPKSRVGLNSVAFAFGDMIKLVVVGAQVIGGCECGGR
DGTGD
Coding >Ophio5|5340
ATGATCTGGTATCTTCTATACCCGCTGCGAGGAACCACGGAGGCGCCTGCGCTCCCCTCCTCGCATCCTCTGTAC
AACGCCTTTGCTCGCTATGGCCGCTACGCTGCCCGTCACGTCGTCGCGACGCTCCTCGTCTCTGCTGCCGTGGCC
ACCGTTCTCGTTTATCCCATTCCTTTCCTCTTCACTAGCGACTTCGTCAACGGCGCTTCCAACTTGCCGCGTCAT
GTCTGGACCGTCGCACAGCCACTTCTGTACAACACCGCCGCGGAGCCAGACATCATCATGCGCTCCATCTGGGTG
CATGCTAGCTATATGCAGGCTTTGAACACCGAGCTACTAGTCTCGGCCCTCAACCTCCAGGACGACCTCCTCGGC
ATCACCAAGAACTTTAGCCCCGCAAGTGCCCGGCTCTTGGTTCTTTCATTCGCCTTTACTGTATTGGGGCTGCTC
TCGAAGAATCAGTCTACGTTTGCCAATGTCACTCTTCGCCACTCCATCGTCTTCAGCGGCAAACGTTTCGAGGAA
CGCCGCTTACTGGCCGCTGATTCCCTCGTCATCACCCTGCTACATCTTCGCGACTCCCCCGTCGGTCGACGGTGG
GAGAGTCGAATACTCGAGCTGCCGCAAAAGGTAGGAAACACGTGGAATATATATCCGCCAGACGGACGGGCCGCT
TCCAGTCAACTCTACGAGTTCCAGTTTCGACCCATCTCCATGCAGGACATAGCTAGCCTCGCCCTTGCCTATGGT
CTCACCCTGGTCTACTTTCTCACAAGCTTGTCCAAGCTGAGGGCTGTCAAGTCTAAAGTCGGTCTCATTGTCACA
GTCCTGGCTCAGATTGTCTTCTCCATCATGTCCAGCTTTACGGTTTGCGCCGTCTTCAACGTCGACCTCTCCCGC
ATCCCGAGGGCAGCGTACCCCCTAGTTGTTCTGGCTATGAGCCTGGAGCACATTTTTAGACTTATCAACGCAGTC
ATTCTCACACCGTTGGAAGACATTGTGAGCAATAGGATAGGCCAAGCCTTCGCCGAAACTGCCCCGACGGCCATG
TTCAGCACCCTGCAAAACGTCATCATTCTGGCGGGCCTCTCCCGTCTGGTTTCTGCCGGGGTGTCGGGATTCTGC
GTATTTGCCGCCATTGCGATCGTATTTGATTTCTTCTACCTCAGCACCTTCTTCTTGGCCGTCTTGAGCGTCGAC
GTCCGCCGGATGGAGCTTGGTGACGCACTGGCCAAAGCCTCGATGCGGCACAATCGTAACAAGCCCGACACGGGT
GTCAGCCGACGCTGGTGGTGGGACCCGGTCTTACAAGGAAGGATCGCAATGTCGACTCGCATCGCTGGCACCATC
GTCATGGTCGGCTTCGTACTCATCGCGCAGTGGCACTTTTTCAGCGACGAGGGCTCATTCAGAAAACTTGTGCGG
TTCTACAGGGACTTGGACCGGGACCAGGGTCCCGGCCACTCGAGGTCGTCCTTGCTCGACAGTGTCCACCAAGCA
AGGAGCCCCACGTCTTGGCTGCGCATACAGGATCACGAAACAGCCCGTGAGGTCATCAACATCATCAAGCCGTCG
TCATACAGCTACGTTGCCCGCGTCTACGATCCGATTGTCTTTGTGTTGAAAAACTCGGACCGCGTGCCGCACAGT
AAAGAGCCTGCCCTGCTACCGGCAGTGTACGATTTCGTCAATCACGAATTGGTCCGCTTCGTTGTCGTCGTCGTC
GTCGTCATTGCGGCTCTCCGTTTGCTGACCAGCTTCCTACTGTGGGAGGACGAGAATCTCAATGACCAACACGAG
CCAGATGAGCTTCCGCGGCTTTCCGTCAGGTCCCTGGCCAGGGGCCACCTCATGGATGTCGTGTTACTGACAACG
TCCGCGGATGGTCATGTCGTGTCCGCCGGGCTTGACAACACGATTCGAGCATGGTCGATACACGGCGTAGGAACG
AGCTACGTGATCGCAAAAGGCGACGAATCGGAAATGGCCGTGTTTCCGGTGGTGGCAATGGCGATTGACGACGAT
TCAAAGTGGCTCGCCTTGTTGTCGAGGCCGAAAAGGAGTGCCTGCTCCAGGGTCAGCTTCTGGGACCTGCAGAGC
AGAGCTTGGGGTTCGTCGATCCAGGCCGACAACCGCCGACACAGGCCGGTGGCTCTCTTGTTTGACCCCAGCGCG
CCCAGCCACCAGCCGAGGGCGCTTGTCGTCCAGCAGGACGGCTCGTTGAGTGAGTTGTTGTCGGGCGAGAAGAAG
GAGCGGCAATTTGTTTCCATGTTTCCTCCGCATCTGACATGCGCCCGCCTGCTGGCCAGAAAGGAAGGCGGTCCG
CAGCCGATCATCTTGGCAGTATCGCGGCAGGGCGAGGTCCACATGGCTGCTCGAGATCAGGGAGTCTGGCGATCT
CGACGACTCGCGATCGGGGGCCTGGGAGAGCCCGGCGCTCATTCGATACAGGTCGTGGCTCCGTTGAATCTGTTC
GTCGTGGCGGCAGGCGACCGTGCTCATCTTATCGACGGCAAAGATGGTGGCGTGCTGCAAACGCTACGAACAGCA
GCGATGCTACCACGGCCTCTGAGATGCGCATACAAACGCCACCCTTCTTCGCAGCTCGAGTCGATGGGTTTGGCG
TCCTTCACTCTTGGTTACGTGGAGGCCGATTCCCGGGATTGCATCCTGCAGACGTACATGCCACCGGAAGATTGT
GACGCTATTTACTTGCAGACGCCGTGCGAGGCTTGGAGCAGCAACTGGTGCACGTGGGAGTCGGCAAGGGAGACG
CGAAAGCGCGTAGCGGACCCGGGTGTGTGGGAGATGGTTTCTGACGGCAGCGCAGTGGGAATACGGTTTAGTGCT
CCTGGTGGCAAGGGATTACAGATGTCGGGTTTGCGGAATCGGTACGGCAAAAGGGTTCCAGAGCCAGACCCGCTC
GAGGGCTGGCAGGTCTGGATGGAGTCGTTACCGGGTTGTCGGCCTGAAGAGAGCGAAAGTCGCCGTCTGATCAAG
GACGGTGAGCAAGCCGGGCACCTACTGGTAACGGAGGTGGGGCCGAAATCGAGAGTTGGGCTGAACTCGGTCGCG
TTTGCGTTTGGCGACATGATCAAGCTCGTCGTCGTCGGGGCACAGGTTATAGGTGGTTGCGAATGTGGTGGCAGG
GACGGGACGGGGGAT
Transcript >Ophio5|5340
ATGATCTGGTATCTTCTATACCCGCTGCGAGGAACCACGGAGGCGCCTGCGCTCCCCTCCTCGCATCCTCTGTAC
AACGCCTTTGCTCGCTATGGCCGCTACGCTGCCCGTCACGTCGTCGCGACGCTCCTCGTCTCTGCTGCCGTGGCC
ACCGTTCTCGTTTATCCCATTCCTTTCCTCTTCACTAGCGACTTCGTCAACGGCGCTTCCAACTTGCCGCGTCAT
GTCTGGACCGTCGCACAGCCACTTCTGTACAACACCGCCGCGGAGCCAGACATCATCATGCGCTCCATCTGGGTG
CATGCTAGCTATATGCAGGCTTTGAACACCGAGCTACTAGTCTCGGCCCTCAACCTCCAGGACGACCTCCTCGGC
ATCACCAAGAACTTTAGCCCCGCAAGTGCCCGGCTCTTGGTTCTTTCATTCGCCTTTACTGTATTGGGGCTGCTC
TCGAAGAATCAGTCTACGTTTGCCAATGTCACTCTTCGCCACTCCATCGTCTTCAGCGGCAAACGTTTCGAGGAA
CGCCGCTTACTGGCCGCTGATTCCCTCGTCATCACCCTGCTACATCTTCGCGACTCCCCCGTCGGTCGACGGTGG
GAGAGTCGAATACTCGAGCTGCCGCAAAAGGTAGGAAACACGTGGAATATATATCCGCCAGACGGACGGGCCGCT
TCCAGTCAACTCTACGAGTTCCAGTTTCGACCCATCTCCATGCAGGACATAGCTAGCCTCGCCCTTGCCTATGGT
CTCACCCTGGTCTACTTTCTCACAAGCTTGTCCAAGCTGAGGGCTGTCAAGTCTAAAGTCGGTCTCATTGTCACA
GTCCTGGCTCAGATTGTCTTCTCCATCATGTCCAGCTTTACGGTTTGCGCCGTCTTCAACGTCGACCTCTCCCGC
ATCCCGAGGGCAGCGTACCCCCTAGTTGTTCTGGCTATGAGCCTGGAGCACATTTTTAGACTTATCAACGCAGTC
ATTCTCACACCGTTGGAAGACATTGTGAGCAATAGGATAGGCCAAGCCTTCGCCGAAACTGCCCCGACGGCCATG
TTCAGCACCCTGCAAAACGTCATCATTCTGGCGGGCCTCTCCCGTCTGGTTTCTGCCGGGGTGTCGGGATTCTGC
GTATTTGCCGCCATTGCGATCGTATTTGATTTCTTCTACCTCAGCACCTTCTTCTTGGCCGTCTTGAGCGTCGAC
GTCCGCCGGATGGAGCTTGGTGACGCACTGGCCAAAGCCTCGATGCGGCACAATCGTAACAAGCCCGACACGGGT
GTCAGCCGACGCTGGTGGTGGGACCCGGTCTTACAAGGAAGGATCGCAATGTCGACTCGCATCGCTGGCACCATC
GTCATGGTCGGCTTCGTACTCATCGCGCAGTGGCACTTTTTCAGCGACGAGGGCTCATTCAGAAAACTTGTGCGG
TTCTACAGGGACTTGGACCGGGACCAGGGTCCCGGCCACTCGAGGTCGTCCTTGCTCGACAGTGTCCACCAAGCA
AGGAGCCCCACGTCTTGGCTGCGCATACAGGATCACGAAACAGCCCGTGAGGTCATCAACATCATCAAGCCGTCG
TCATACAGCTACGTTGCCCGCGTCTACGATCCGATTGTCTTTGTGTTGAAAAACTCGGACCGCGTGCCGCACAGT
AAAGAGCCTGCCCTGCTACCGGCAGTGTACGATTTCGTCAATCACGAATTGGTCCGCTTCGTTGTCGTCGTCGTC
GTCGTCATTGCGGCTCTCCGTTTGCTGACCAGCTTCCTACTGTGGGAGGACGAGAATCTCAATGACCAACACGAG
CCAGATGAGCTTCCGCGGCTTTCCGTCAGGTCCCTGGCCAGGGGCCACCTCATGGATGTCGTGTTACTGACAACG
TCCGCGGATGGTCATGTCGTGTCCGCCGGGCTTGACAACACGATTCGAGCATGGTCGATACACGGCGTAGGAACG
AGCTACGTGATCGCAAAAGGCGACGAATCGGAAATGGCCGTGTTTCCGGTGGTGGCAATGGCGATTGACGACGAT
TCAAAGTGGCTCGCCTTGTTGTCGAGGCCGAAAAGGAGTGCCTGCTCCAGGGTCAGCTTCTGGGACCTGCAGAGC
AGAGCTTGGGGTTCGTCGATCCAGGCCGACAACCGCCGACACAGGCCGGTGGCTCTCTTGTTTGACCCCAGCGCG
CCCAGCCACCAGCCGAGGGCGCTTGTCGTCCAGCAGGACGGCTCGTTGAGTGAGTTGTTGTCGGGCGAGAAGAAG
GAGCGGCAATTTGTTTCCATGTTTCCTCCGCATCTGACATGCGCCCGCCTGCTGGCCAGAAAGGAAGGCGGTCCG
CAGCCGATCATCTTGGCAGTATCGCGGCAGGGCGAGGTCCACATGGCTGCTCGAGATCAGGGAGTCTGGCGATCT
CGACGACTCGCGATCGGGGGCCTGGGAGAGCCCGGCGCTCATTCGATACAGGTCGTGGCTCCGTTGAATCTGTTC
GTCGTGGCGGCAGGCGACCGTGCTCATCTTATCGACGGCAAAGATGGTGGCGTGCTGCAAACGCTACGAACAGCA
GCGATGCTACCACGGCCTCTGAGATGCGCATACAAACGCCACCCTTCTTCGCAGCTCGAGTCGATGGGTTTGGCG
TCCTTCACTCTTGGTTACGTGGAGGCCGATTCCCGGGATTGCATCCTGCAGACGTACATGCCACCGGAAGATTGT
GACGCTATTTACTTGCAGACGCCGTGCGAGGCTTGGAGCAGCAACTGGTGCACGTGGGAGTCGGCAAGGGAGACG
CGAAAGCGCGTAGCGGACCCGGGTGTGTGGGAGATGGTTTCTGACGGCAGCGCAGTGGGAATACGGTTTAGTGCT
CCTGGTGGCAAGGGATTACAGATGTCGGGTTTGCGGAATCGGTACGGCAAAAGGGTTCCAGAGCCAGACCCGCTC
GAGGGCTGGCAGGTCTGGATGGAGTCGTTACCGGGTTGTCGGCCTGAAGAGAGCGAAAGTCGCCGTCTGATCAAG
GACGGTGAGCAAGCCGGGCACCTACTGGTAACGGAGGTGGGGCCGAAATCGAGAGTTGGGCTGAACTCGGTCGCG
TTTGCGTTTGGCGACATGATCAAGCTCGTCGTCGTCGGGGCACAGGTTATAGGTGGTTGCGAATGTGGTGGCAGG
GACGGGACGGGGGATTGA
Gene >Ophio5|5340
ATGATCTGGTATCTTCTATACCCGCTGCGAGGGTGAGCAGTGACTCTTTTTGCTCTCTGCCCTGTATCCTATTCC
CGAGTCTTGGGGAGCAGCCGTATTTTTGCCCTGGTCCGGAGCTAACTTTCTACCGTGTTTCCAGAACCACGGAGG
CGCCTGCGCTCCCCTCCTCGCATCCTCTGTACAACGCCTTTGCTCGCTATGGCCGCTACGCTGCCCGTCACGTCG
TCGCGACGCTCCTCGTCTCTGCTGCCGTGGCCACCGTTCTCGTTTATCCCATTCCTTTCCTCTTCACTAGCGACT
TCGTCAACGGCGCTTCCAACTTGCCGCGTCATGTCTGGACCGTCGCACAGCCACTTCTGTACAACACCGCCGCGG
AGCCAGACATCATCATGCGCTCCATCTGGGTGCATGCTAGCTATATGCAGGCTTTGAACACCGAGCTACTAGTCT
CGGCCCTCAACCTCCAGGACGACCTCCTCGGCATCACCAAGAACTTTAGCCCCGCAAGTGCCCGGCGTACGCCTC
CTTGGACCGACTTACCCAACGAGGATTTGTCGTTGAGCCAGCGAGATGCAATTCATGTCGCTAATGGTCTGACTT
CGCAGTCTTGGTTCTTTCATTCGCCTTTACTGTATTGGGGCTGCTCTCGTGAGCGCATCTTGGCCGACGACGATA
TCCTCTCAACCGTCAATAATAGGAAGAATCAGTCTACGTTTGCCAATGTCACTCTTCGCCACTCCATCGTCTTCA
GCGGCAAACGTTTCGAGGAACGCCGCTTACTGGCCGCTGATTCCCTCGTCATCACCCTGCTACATCTTCGCGACT
CCCCCGTCGGTCGACGGTGGGAGAGTCGAATACTCGAGCTGCCGCAAAAGGTAGGAAACACGTGGAATATATATC
CGCCAGACGGACGGGCCGCTTCCAGTCAACTCTACGAGTTCCAGTTTCGACCCATCTCCATGCAGGACATAGCTA
GCCTCGCCCTTGCCTATGGTCTCACCCTGGTCTACTTTCTCACAAGCTTGTCCAAGCTGAGGGCTGTCAAGTCTA
AAGTCGGTCTCATTGTCACAGTCCTGGCTCAGATTGTCTTCTCCATCATGTCCAGCTTTACGGTTTGCGCCGTCT
TCAACGTCGACCTCTCCCGCATCCCGAGGGCAGCGTACCCCCTAGTTGTTCTGGCTATGAGCCTGGAGCACATTT
TTAGACTTATCAACGCAGTCATTCTCACACCGTTGGAAGACATTGTGAGCAATAGGATAGGCCAAGCCTTCGCCG
AAACTGCCCCGACGGCCATGTTCAGCACCCTGCAAAACGTCATCATTCTGGCGGGCCTCTCCCGTCTGGTTTCTG
CCGGGGTGTCGGGATTCTGCGTATTTGCCGCCATTGCGATCGTATTTGATTTCTTCTACCTCAGCACCTTCTTCT
TGGCCGTCTTGAGCGTCGACGTCCGCCGGATGGAGCTTGGTGACGCACTGGCCAAAGCCTCGATGCGGCACAATC
GTAACAAGCCCGACACGGGTGTCAGCCGACGCTGGTGGTGGGACCCGGTCTTACAAGGAAGGATCGCAATGTCGA
CTCGCATCGCTGGCACCATCGTCATGGTCGGCTTCGTACTCATCGCGCAGTGGCACTTTTTCAGCGACGAGGGCT
CATTCAGAAAACTTGTGCGGTTCTACAGGGACTTGGACCGGGACCAGGGTCCCGGCCACTCGAGGTCGTCCTTGC
TCGACAGTGTCCACCAAGCAAGGAGCCCCACGTCTTGGCTGCGCATACAGGATCACGAAACAGCCCGTGAGGTCA
TCAACATCATCAAGCCGTCGTCATACAGCTACGTTGCCCGCGTCTACGATCCGATTGTCTTTGTGTTGAAAAACT
CGGACCGCGTGCCGCACAGTAAAGAGCCTGCCCTGCTACCGGCAGTGTACGATTTCGTCAATCACGAATTGGTCC
GCTTCGTTGTCGTCGTCGTCGTCGTCATTGCGGCTCTCCGTTTGCTGACCAGCTTCCTACTGTGGGAGGACGAGA
ATCTCAATGACCAACACGAGCCAGATGAGCTTCCGCGGCTTTCCGTCAGGTCCCTGGCCAGGGGCCACCTCATGG
ATGTCGTGTTACTGACAACGTCCGCGGATGGTCATGTCGTGTCCGCCGGGCTTGACAACACGATTCGAGCATGGT
CGATACACGGCGTAGGAACGAGCTACGTGATCGCAAAAGGCGACGAATCGGAAATGGCCGTGTTTCCGGTGGTGG
CAATGGCGATTGACGACGATTCAAAGTGGCTCGCCTTGTTGTCGAGGCCGAAAAGGAGTGCCTGCTCCAGGGTCA
GCTTCTGGGACCTGCAGAGCAGAGCTTGGGGTTCGTCGATCCAGGCCGACAACCGCCGACACAGGCCGGTGGCTC
TCTTGTTTGACCCCAGCGCGCCCAGCCACCAGCCGAGGGCGCTTGTCGTCCAGCAGGACGGCTCGTTGAGTGAGT
TGTTGTCGGGCGAGAAGAAGGAGCGGCAATTTGTTTCCATGTTTCCTCCGCATCTGACATGCGCCCGCCTGCTGG
CCAGAAAGGGTAAAATGACACCAATTGGGCTCTCGAGCCATGTCCCAAAAAACTTGTTGGCTGCAGAGTGCGCTG
ATCATCATGTCATCTCTCTAGAAGGCGGTCCGCAGCCGATCATCTTGGCAGTATCGCGGCAGGGCGAGGTCCACA
TGGCTGCTCGAGATCAGGGAGTCTGGCGATCTCGACGACTCGCGATCGGGGGCCTGGGAGAGCCCGGCGCTCATT
CGATACAGGTCGTGGCTCCGTTGAATCTGTTCGTCGTGGCGGCAGGCGACCGTGCTCATCTTATCGACGGCAAAG
ATGGTGGCGTGCTGCAAACGCTACGAACAGCAGCGATGCTACCACGGCCTCTGAGATGCGCATACAAACGCCACC
CTTCTTCGCAGCTCGAGTCGATGGGTTTGGCGTCCTTCACTCTTGGTTACGTGGAGGCCGATTCCCGGGATTGCA
TCCTGCAGACGTACATGCCACCGGAAGATTGTGACGCTATTTACTTGCAGACGCCGTGCGAGGCTTGGAGCAGCA
ACTGGTGCACGTGGGAGTCGGCAAGGGAGACGCGAAAGCGCGTAGCGGACCCGGGTGTGTGGGAGATGGTTTCTG
ACGGCAGCGCAGTGGGAATACGGTTTAGTGCTCCTGGTGGCAAGGGATTACAGATGTCGGGTTTGCGGAATCGGT
ACGGCAAAAGGGTTCCAGAGCCAGACCCGCTCGAGGGCTGGCAGGTCTGGATGGAGTCGTTACCGGGTTGTCGGC
CTGAAGAGAGCGAAAGTCGCCGTCTGATCAAGGACGGTGAGCAAGCCGGGCACCTACTGGTAACGGAGGTGGGGC
CGAAATCGAGAGTTGGGCTGAACTCGGTCGCGTTTGCGTTTGGCGACATGATCAAGCTCGTCGTCGTCGGGGCAC
AGGTGCGTCTCAAGGGGAGGTCCGAGGGCCAGGCTGGCGAGGCGTTGATGAGCGCTGGGAGCAGACGGCGGAGGC
CAGGATCCGTCTTGAGGGGGCGAGCTGCGTCCCGAGGCTAGGTAGGTCTGGCTGGTAGCATGTGTGCGAAGGAGA
CGGCAATTGGACCGGCATCAAGGTTATAGGTAAGCTCTGCGTGACAGTGACGCTGTAAAGCATGGCTACCTACAC
CTACCTACCTACCTACCTACCTATATGGCCTGTATGCCCATGTCGTCCTGATTCGTCATGACTTGTTGAAGATTA
CAAGATGGTCAACGGACCAACCTGACTGACAACCATGCATAGGTGGTTGCGAATGTGGTGGCAGGGACGGGACGG
GGGATTGA

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