Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophio5|5200
Gene name
Location	scaffold_42:19690..23293
Strand	-
Gene length (bp)	3603
Transcript length (bp)	3228
Coding sequence length (bp)	3225
Protein length (aa)	1075

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00069	Pkinase	Protein kinase domain	1.1E-16	244	459
PF07714	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	2.1E-08	205	391

Swissprot hits

GO

GO Term	Description	Terminal node
GO:0005524	ATP binding	Yes
GO:0004672	protein kinase activity	Yes
GO:0006468	protein phosphorylation	Yes
GO:0043412	macromolecule modification	No
GO:0071704	organic substance metabolic process	No
GO:0032555	purine ribonucleotide binding	No
GO:0006793	phosphorus metabolic process	No
GO:0016740	transferase activity	No
GO:0003674	molecular_function	No
GO:0044237	cellular metabolic process	No
GO:0008152	metabolic process	No
GO:0043167	ion binding	No
GO:0140096	catalytic activity, acting on a protein	No
GO:0016310	phosphorylation	No
GO:0044238	primary metabolic process	No
GO:0006796	phosphate-containing compound metabolic process	No
GO:1901564	organonitrogen compound metabolic process	No
GO:0043168	anion binding	No
GO:0008150	biological_process	No
GO:0043170	macromolecule metabolic process	No
GO:0000166	nucleotide binding	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0003824	catalytic activity	No
GO:0006807	nitrogen compound metabolic process	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0016772	transferase activity, transferring phosphorus-containing groups	No
GO:0036094	small molecule binding	No
GO:0016301	kinase activity	No
GO:0097159	organic cyclic compound binding	No
GO:0097367	carbohydrate derivative binding	No
GO:1901265	nucleoside phosphate binding	No
GO:0032553	ribonucleotide binding	No
GO:0036211	protein modification process	No
GO:0016773	phosphotransferase activity, alcohol group as acceptor	No
GO:0019538	protein metabolic process	No
GO:1901363	heterocyclic compound binding	No
GO:0017076	purine nucleotide binding	No
GO:0030554	adenyl nucleotide binding	No
GO:0009987	cellular process	No
GO:0005488	binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophio5|5200 MPPNSSRFPQDLISRFYQPRRDQHGDQQLASPRLAMAPDDYHRTGNDLYHQLWQRLEKRDDETLRFAARGTSSQV LDDDALQRFVRSLDLRDPPLTEALFAQRIKERQLLDFLATLIFAACGVEAARTFTTKLAAASVWPVRDRLGEAIG TLPANRRQLEELFGSTVDADKFLSKQAYFCTVVLRKREEVYVRNGDFQRLPYLQEKPLGCGSFGSVFKVTIAAGH FCDGHSDMGFGYNTEPIEMARKDYITSDAFRAKDEYQVMKKILSSPTRKCDNIVESLGCLQIGSRYSLFMPLAIC DLHDYILENHRAKPRTRRAKADIVRCAAGLASGLHFLHEEIMTPDFERLVCYHMDLTPSNILIFREDKGDGLQNV WKLSDFGMSRVKIRRDSRGGNVKEKDFNNLFVRRVKPRDPSASATLNLRGEGTYLAPESIAATPLMQASSDVWSL GCVVSVIFTYLEEGGDGVERYQDGRVQHRKADGYDRFFLRGTKFKKSQVHPLVKSWHTELIGKATKRDANEGEAL AYVLRSLESDVLQVDHGSRWRAKSVKEMLETAFKLYRGLGEGLVSTDHRLPTPPNPLANVFRKVEPSSGAEVCAW LVSPSDDFKGCVVSPDAAHVVYWTDITIFLYTSQALNHAIGEVLTPSAEFTLNETDCFWKSVCMSRSRLIAYTTG CNHCYLFNLEGGTAVDANLGDWCRTVLQLPEVHRLAISPNGSKLVCVAQHEDGGSEPGSLFHASVPDLFRMPRGG RAPDTSRGPDTTTASGGWRKLALEWLAAEVVHLSVSDTNDIDLVVRPEPTARSPEHKIPIMHVSLNEATIDTLNI QSLGYDSSSTGSFFTAFCPFRYEATCAVVTREKRFHIQKFAGMDVSRELQKDIPNYRVRRLLMGLYGDNRLFALG TTSASHRMLLLEIQVPQPDTDMEVRQVAQLPGLSYDDDFSVMLSDDGDDERRLFCLEAGTQVKPGSEVKPVTTDA NVNSWQQQQQLDRRAILAAVSTKHLIHVEEARKSHGFGVSMIVSSRLLGMVPKAPQKLPSHVQVILEKTFSWAHP NPYRDDSKTVRVTVLHYNVSYIASV
Coding	>Ophio5|5200 ATGCCGCCCAACAGCAGCCGTTTCCCCCAAGACCTAATCTCTCGCTTCTACCAACCAAGACGAGACCAGCACGGA GACCAGCAACTGGCCTCGCCACGGCTGGCAATGGCGCCAGACGACTATCACCGGACTGGTAATGACCTCTACCAT CAGCTCTGGCAGAGGTTGGAAAAAAGAGACGATGAGACGCTTCGGTTCGCAGCTCGAGGAACCAGCAGCCAGGTG CTAGACGACGACGCGCTGCAGCGCTTCGTACGAAGTCTTGACCTGCGTGATCCCCCTCTCACCGAGGCACTGTTC GCCCAGAGGATCAAGGAACGACAGCTGTTGGACTTCCTGGCGACGCTCATCTTCGCAGCCTGCGGCGTAGAGGCA GCAAGGACCTTTACCACCAAGCTCGCGGCGGCTTCTGTCTGGCCAGTGCGAGACAGGCTCGGAGAGGCCATCGGC ACGCTGCCGGCCAATCGCCGACAGCTGGAGGAGTTATTCGGCAGCACGGTCGACGCCGACAAGTTCCTATCCAAG CAGGCCTACTTCTGCACTGTGGTACTGCGCAAGAGAGAGGAGGTTTACGTCCGAAATGGCGACTTTCAGCGGCTA CCATATCTGCAGGAGAAGCCGCTGGGGTGTGGCTCGTTTGGCAGCGTCTTCAAGGTGACCATCGCGGCCGGCCAC TTCTGCGACGGCCACTCAGACATGGGCTTTGGCTACAATACGGAGCCCATAGAAATGGCGCGGAAAGACTACATT ACGTCGGATGCCTTCCGGGCCAAGGACGAATACCAGGTCATGAAGAAGATTCTTAGCTCGCCGACGCGCAAGTGC GATAACATTGTCGAGAGCCTCGGTTGCCTCCAGATCGGATCTAGATATAGCCTCTTTATGCCGCTGGCTATCTGC GACCTACACGACTACATCCTAGAGAACCATCGTGCTAAGCCACGGACCAGGCGGGCCAAAGCAGACATTGTGCGG TGTGCTGCGGGGCTCGCCAGCGGCCTTCACTTTCTGCACGAGGAGATAATGACGCCGGACTTTGAGCGGCTCGTC TGCTATCACATGGACCTCACCCCTAGCAACATTCTCATCTTCCGCGAGGACAAGGGAGACGGGCTGCAGAACGTG TGGAAACTCAGCGACTTCGGCATGTCTCGCGTCAAGATCCGACGCGACTCGCGAGGAGGCAACGTCAAGGAGAAA GACTTTAATAACCTGTTTGTCCGGCGGGTGAAGCCCCGAGATCCGTCCGCCTCGGCCACTCTGAACCTGCGCGGA GAAGGCACCTACTTGGCGCCTGAGTCCATCGCGGCCACTCCTTTGATGCAAGCAAGCAGCGACGTGTGGTCCTTG GGCTGCGTCGTGAGCGTCATCTTCACCTACCTGGAAGAGGGCGGCGATGGAGTGGAGCGCTACCAGGATGGCCGC GTGCAGCATCGCAAGGCAGACGGCTACGATCGCTTCTTCCTGCGTGGAACGAAGTTCAAAAAGAGCCAAGTCCAT CCGCTGGTCAAATCGTGGCATACAGAGCTCATTGGCAAGGCGACGAAGCGAGATGCCAATGAGGGCGAAGCCTTG GCCTACGTGTTGAGGAGTCTGGAATCTGACGTGCTCCAGGTGGACCACGGCAGCAGATGGCGCGCAAAAAGCGTA AAGGAAATGCTCGAGACGGCTTTTAAGTTGTATCGAGGCCTGGGCGAAGGCCTGGTTTCGACGGACCACAGGCTG CCAACGCCTCCCAACCCCCTGGCCAACGTCTTCCGAAAAGTCGAGCCCTCGTCGGGAGCAGAGGTCTGCGCGTGG CTCGTGTCACCGTCGGATGACTTCAAGGGTTGTGTGGTCTCCCCTGACGCAGCACACGTCGTCTACTGGACCGAC ATTACGATTTTTCTTTACACGTCACAGGCACTAAATCACGCAATTGGCGAAGTGCTGACGCCGTCGGCCGAATTT ACGCTCAACGAGACGGATTGCTTTTGGAAAAGCGTCTGCATGAGTCGAAGCCGTCTCATAGCTTACACGACGGGT TGCAACCACTGTTATCTGTTCAACCTCGAAGGCGGGACGGCCGTCGACGCCAACCTGGGCGACTGGTGCAGGACG GTGTTACAGCTGCCGGAGGTGCACCGCCTGGCCATTTCTCCCAACGGCTCGAAGCTGGTGTGTGTGGCGCAGCAC GAGGATGGGGGCAGTGAGCCAGGCTCACTGTTCCACGCCTCCGTGCCGGATCTGTTTCGAATGCCACGAGGCGGA CGGGCTCCGGATACAAGCCGAGGGCCGGACACCACGACGGCGTCTGGTGGCTGGAGGAAGCTGGCGCTCGAGTGG TTGGCAGCCGAAGTCGTCCATCTGTCCGTGTCTGACACCAACGACATCGATCTGGTGGTTCGGCCCGAGCCGACG GCCCGCAGCCCGGAGCACAAGATCCCCATCATGCACGTTTCGCTCAACGAGGCCACCATCGACACGCTTAACATC CAGTCGCTGGGCTACGACAGCAGCAGCACCGGCAGCTTCTTCACGGCCTTTTGCCCCTTCCGGTACGAAGCCACC TGCGCCGTGGTGACTCGCGAGAAACGATTCCACATACAAAAATTTGCCGGAATGGACGTCAGTCGCGAGTTGCAA AAGGACATTCCCAACTATCGCGTGCGCAGGCTCCTGATGGGCTTGTACGGCGACAATCGGCTATTTGCGCTGGGC ACGACATCGGCCAGCCATCGCATGCTGCTGCTTGAGATTCAGGTTCCGCAGCCCGATACGGACATGGAGGTACGG CAGGTGGCCCAGCTGCCTGGCCTATCCTACGATGACGACTTTTCCGTGATGCTGTCGGACGACGGTGATGACGAA CGGAGGCTCTTTTGCCTTGAAGCCGGGACCCAAGTCAAGCCTGGAAGTGAAGTAAAGCCAGTGACTACGGACGCA AACGTCAACAGCTGGCAGCAGCAGCAGCAGCTCGACCGGAGGGCGATACTTGCAGCCGTTTCAACGAAACACCTA ATTCATGTCGAAGAGGCTCGAAAGAGTCACGGATTCGGAGTCTCAATGATCGTTTCGTCCCGACTTCTTGGCATG GTCCCAAAGGCTCCGCAGAAGCTGCCTAGTCACGTCCAAGTAATATTGGAGAAGACCTTTTCTTGGGCCCATCCG AATCCCTACCGTGACGACTCTAAGACTGTCCGCGTTACTGTGCTGCATTACAACGTTTCGTATATTGCTTCTGTT
Transcript	>Ophio5|5200 ATGCCGCCCAACAGCAGCCGTTTCCCCCAAGACCTAATCTCTCGCTTCTACCAACCAAGACGAGACCAGCACGGA GACCAGCAACTGGCCTCGCCACGGCTGGCAATGGCGCCAGACGACTATCACCGGACTGGTAATGACCTCTACCAT CAGCTCTGGCAGAGGTTGGAAAAAAGAGACGATGAGACGCTTCGGTTCGCAGCTCGAGGAACCAGCAGCCAGGTG CTAGACGACGACGCGCTGCAGCGCTTCGTACGAAGTCTTGACCTGCGTGATCCCCCTCTCACCGAGGCACTGTTC GCCCAGAGGATCAAGGAACGACAGCTGTTGGACTTCCTGGCGACGCTCATCTTCGCAGCCTGCGGCGTAGAGGCA GCAAGGACCTTTACCACCAAGCTCGCGGCGGCTTCTGTCTGGCCAGTGCGAGACAGGCTCGGAGAGGCCATCGGC ACGCTGCCGGCCAATCGCCGACAGCTGGAGGAGTTATTCGGCAGCACGGTCGACGCCGACAAGTTCCTATCCAAG CAGGCCTACTTCTGCACTGTGGTACTGCGCAAGAGAGAGGAGGTTTACGTCCGAAATGGCGACTTTCAGCGGCTA CCATATCTGCAGGAGAAGCCGCTGGGGTGTGGCTCGTTTGGCAGCGTCTTCAAGGTGACCATCGCGGCCGGCCAC TTCTGCGACGGCCACTCAGACATGGGCTTTGGCTACAATACGGAGCCCATAGAAATGGCGCGGAAAGACTACATT ACGTCGGATGCCTTCCGGGCCAAGGACGAATACCAGGTCATGAAGAAGATTCTTAGCTCGCCGACGCGCAAGTGC GATAACATTGTCGAGAGCCTCGGTTGCCTCCAGATCGGATCTAGATATAGCCTCTTTATGCCGCTGGCTATCTGC GACCTACACGACTACATCCTAGAGAACCATCGTGCTAAGCCACGGACCAGGCGGGCCAAAGCAGACATTGTGCGG TGTGCTGCGGGGCTCGCCAGCGGCCTTCACTTTCTGCACGAGGAGATAATGACGCCGGACTTTGAGCGGCTCGTC TGCTATCACATGGACCTCACCCCTAGCAACATTCTCATCTTCCGCGAGGACAAGGGAGACGGGCTGCAGAACGTG TGGAAACTCAGCGACTTCGGCATGTCTCGCGTCAAGATCCGACGCGACTCGCGAGGAGGCAACGTCAAGGAGAAA GACTTTAATAACCTGTTTGTCCGGCGGGTGAAGCCCCGAGATCCGTCCGCCTCGGCCACTCTGAACCTGCGCGGA GAAGGCACCTACTTGGCGCCTGAGTCCATCGCGGCCACTCCTTTGATGCAAGCAAGCAGCGACGTGTGGTCCTTG GGCTGCGTCGTGAGCGTCATCTTCACCTACCTGGAAGAGGGCGGCGATGGAGTGGAGCGCTACCAGGATGGCCGC GTGCAGCATCGCAAGGCAGACGGCTACGATCGCTTCTTCCTGCGTGGAACGAAGTTCAAAAAGAGCCAAGTCCAT CCGCTGGTCAAATCGTGGCATACAGAGCTCATTGGCAAGGCGACGAAGCGAGATGCCAATGAGGGCGAAGCCTTG GCCTACGTGTTGAGGAGTCTGGAATCTGACGTGCTCCAGGTGGACCACGGCAGCAGATGGCGCGCAAAAAGCGTA AAGGAAATGCTCGAGACGGCTTTTAAGTTGTATCGAGGCCTGGGCGAAGGCCTGGTTTCGACGGACCACAGGCTG CCAACGCCTCCCAACCCCCTGGCCAACGTCTTCCGAAAAGTCGAGCCCTCGTCGGGAGCAGAGGTCTGCGCGTGG CTCGTGTCACCGTCGGATGACTTCAAGGGTTGTGTGGTCTCCCCTGACGCAGCACACGTCGTCTACTGGACCGAC ATTACGATTTTTCTTTACACGTCACAGGCACTAAATCACGCAATTGGCGAAGTGCTGACGCCGTCGGCCGAATTT ACGCTCAACGAGACGGATTGCTTTTGGAAAAGCGTCTGCATGAGTCGAAGCCGTCTCATAGCTTACACGACGGGT TGCAACCACTGTTATCTGTTCAACCTCGAAGGCGGGACGGCCGTCGACGCCAACCTGGGCGACTGGTGCAGGACG GTGTTACAGCTGCCGGAGGTGCACCGCCTGGCCATTTCTCCCAACGGCTCGAAGCTGGTGTGTGTGGCGCAGCAC GAGGATGGGGGCAGTGAGCCAGGCTCACTGTTCCACGCCTCCGTGCCGGATCTGTTTCGAATGCCACGAGGCGGA CGGGCTCCGGATACAAGCCGAGGGCCGGACACCACGACGGCGTCTGGTGGCTGGAGGAAGCTGGCGCTCGAGTGG TTGGCAGCCGAAGTCGTCCATCTGTCCGTGTCTGACACCAACGACATCGATCTGGTGGTTCGGCCCGAGCCGACG GCCCGCAGCCCGGAGCACAAGATCCCCATCATGCACGTTTCGCTCAACGAGGCCACCATCGACACGCTTAACATC CAGTCGCTGGGCTACGACAGCAGCAGCACCGGCAGCTTCTTCACGGCCTTTTGCCCCTTCCGGTACGAAGCCACC TGCGCCGTGGTGACTCGCGAGAAACGATTCCACATACAAAAATTTGCCGGAATGGACGTCAGTCGCGAGTTGCAA AAGGACATTCCCAACTATCGCGTGCGCAGGCTCCTGATGGGCTTGTACGGCGACAATCGGCTATTTGCGCTGGGC ACGACATCGGCCAGCCATCGCATGCTGCTGCTTGAGATTCAGGTTCCGCAGCCCGATACGGACATGGAGGTACGG CAGGTGGCCCAGCTGCCTGGCCTATCCTACGATGACGACTTTTCCGTGATGCTGTCGGACGACGGTGATGACGAA CGGAGGCTCTTTTGCCTTGAAGCCGGGACCCAAGTCAAGCCTGGAAGTGAAGTAAAGCCAGTGACTACGGACGCA AACGTCAACAGCTGGCAGCAGCAGCAGCAGCTCGACCGGAGGGCGATACTTGCAGCCGTTTCAACGAAACACCTA ATTCATGTCGAAGAGGCTCGAAAGAGTCACGGATTCGGAGTCTCAATGATCGTTTCGTCCCGACTTCTTGGCATG GTCCCAAAGGCTCCGCAGAAGCTGCCTAGTCACGTCCAAGTAATATTGGAGAAGACCTTTTCTTGGGCCCATCCG AATCCCTACCGTGACGACTCTAAGACTGTCCGCGTTACTGTGCTGCATTACAACGTTTCGTATATTGCTTCTGTT TAG
Gene	>Ophio5|5200 ATGCCGCCCAACAGCAGCCGTTTCCCCCAAGACCTAATCTCTCGCTTCTACCAACCAAGACGAGACCAGCACGGA GACCAGCAACTGGCCTCGCCACGGCTGGCAATGGCGCCAGACGACTATCACCGGACTGGTAATGACCTCTACCAT CAGCTCTGGCAGAGGTTGGAAAAAAGAGACGATGAGACGCTTCGGTTCGCAGCTCGAGGAACCAGCAGCCAGGTG CTAGACGACGACGCGCTGCAGCGCTTCGTACGAAGTCTTGACCTGCGTGATCCCCCTCTCACCGAGGCACTGTTC GCCCAGAGGATCAAGGAACGACAGCTGTTGGACTTCCTGGCGACGCTCATCTTCGCAGCCTGCGGCGTAGAGGCA GCAAGGACCTTTACCACCAAGCTCGCGGCGGCTTCTGTCTGGCCAGTGCGAGACAGGCTCGGAGAGGCCATCGGC ACGCTGCCGGCCAATCGCCGACAGCTGGAGGAGTTATTCGGCAGCACGGTCGACGCCGACAAGTTCCTATCCAAG CAGGCCTACTTCTGCACTGTGGTACTGCGCAAGAGAGAGGAGGTTTACGTCCGAAATGGCGACTTTCAGCGGCTA CCATATCTGCAGGAGAAGCCGCTGGGGTGTGGCTCGTTTGGCAGCGTCTTCAAGGTGACCATCGCGGCCGGCCAC TTCTGCGACGGCCACTCAGACATGGGCTTTGGCTACAATACGGAGCCCATAGAAATGGCGCGGAAAGACTACATT ACGTCGGATGCCTTCCGGGCCAAGGACGAATACCAGGTCATGAAGAAGATTCTTAGCTCGCCGACGCGCAAGTGC GATAACATTGTCGAGAGCCTCGGTTGCCTCCAGATCGGATCTAGATATAGCCTCTTTATGCCGCTGGCTATCTGC GACCTACACGACTACATCCTAGAGAACCATCGTGCTAAGCCACGGACCAGGCGGGCCAAAGCAGACATTGTGCGG TGTGCTGCGGGGCTCGCCAGCGGCCTTCACTTTCTGCACGAGGAGATAATGACGCCGGACTTTGAGCGGCTCGTC TGCTATCACATGGACCTCACCCCTAGCAACATTCTCATCTTCCGCGAGGACAAGGGAGACGGGCTGCAGAACGTG TGGAAACTCAGCGACTTCGGCATGTCTCGCGTCAAGATCCGACGCGACTCGCGAGGAGGCAACGTCAAGGAGAAA GACTTTAATAACCTGTTTGTCCGGCGGGTGAAGCCCCGAGATCCGTCCGCCTCGGCCACTCTGAACCTGCGCGGA GAAGGCACCTACTTGGCGCCTGAGTCCATCGCGGCCACTCCTTTGATGCAAGCAAGCAGCGACGTGTGGTCCTTG GGCTGCGTCGTGAGCGTCATCTTCACCTACCTGGAAGAGGGCGGCGATGGAGTGGAGCGCTACCAGGATGGCCGC GTGCAGCATCGCAAGGCAGACGGCTACGATCGCTTCTTCCTGCGTGGAACGAAGTTCAAAAAGAGCCAAGTCCAT CCGCTGGTCAAATCGTGGCATACAGAGCTCATTGGCAAGGCGACGAAGCGAGATGCCAATGAGGGCGAAGCCTTG GCCTACGTGTTGAGGAGTCTGGAATCTGACGTGCTCCAGGTGGACCACGGCAGCAGATGGCGCGCAAAAAGCGTA AAGGAAATGCTCGAGACGGCTTTTAAGTTGTATCGAGGCCTGGGCGAAGGCCTGGTTTCGACGGACCACAGGCTG CCAACGCCTCCCAACCCCCTGGCCAACGTCTTCCGAAAGTGAGCATGACCCCTTGGCTGCCTGTTGTTCAGAGGC TGACCCTGCTGTCTTGAAAGAGTCGAGCCCTCGTCGGGAGCAGAGGTCTGCGCGTGGCTCGTGTCACCGTCGGAT GACTTCAAGGGTTGTGTGGTCTCCCCTGACGCAGCACACGTCGTCTACTGGACCGACATTACGATTTTTCTTTAC ACGTCACAGGCACTAAATCACGCAATTGGCGAAGTGCTGACGCCGTCGGCCGAATTTACGCTCAACGAGACGGAT TGCTTTTGGAAAAGCGTCTGCATGAGTCGAAGCCGTCTCATAGCTTACACGACGGGTTGCAACCACGTGCGTACC TCTAAACAGGGTCGTGGCCTCTCCAGCTGACGCTCGCAGTGTTATCTGTTCAACCTCGAAGGCGGGACGGCCGTC GACGCCAACCTGGGCGACTGGTGCAGGACGGTGTTACAGCTGCCGGAGGTGCACCGCCTGGCCATTTCTCCCAAC GGCTCGAAGCTGGTGTGTGTGGCGCAGCACGAGGATGGGGGCAGTGAGCCAGGCTCACTGTTCCACGCCTCCGTG CCGGATCTGTTTCGAATGCCACGAGGCGGACGGGCTCCGGATACAAGCCGAGGGCCGGACACCACGACGGCGTCT GGTGGCTGGAGGAAGCTGGCGCTCGAGTGGTTGGCAGCCGAAGTCGTCCATCTGTCCGTGTCTGACACCAACGAC ATCGATCTGGTGGTTCGGCCCGAGCCGACGGCCCGCAGCCCGGAGCACAAGATCCCCATCATGCACGTTTCGCTC AACGAGGCCACCATCGACACGCTTAACATCCAGTCGCTGGTAGGTCTTGTCTCTCTAAACGAAGGATCCGTCATT CCTAAGCCTCGGCAGGGCTACGACAGCAGCAGCACCGGCAGCTTCTTCACGGCCTTTTGCCCCTTCCGGTACGAA GCCACCTGCGCCGTGGTGACTCGCGAGAAACGATTCCACATACAAAAATTTGCCGGAATGGACGTCAGTCGCGAG TTGCAAAAGGACATTCCCAACTATCGCGTGCGCAGGCTCCTGATGGGCTTGTACGGCGACAATCGGCTATTTGCG CTGGGCACGACATCGGCCAGCCATCGCATGCTGCTGCTTGAGATTCAGGTTCCGCAGCCCGATACGGACATGGAG GTACGGCAGGTGGCCCAGCTGCCTGGCCTATCCTACGATGACGACTTTTCCGTGATGCTGTCGGACGACGGTGAT GACGAGTATATTCTGGTGGCGGCCTTGACGCGGAACATCTACAGGGTGCCAATTCTTAAGACGGAGGCTCTTTTG CCTTGAAGCCGGGACCCAAGTCAAGGTGAGTTGGTGTCCGTATGTGCGATGATGGCTCGGTTTTTGACACTTGAA CTCAGCCTGGAAGTGAAGTAAAGCCAGTGACTACGGACGCAAACGTCAACAGCTGGCAGCAGCAGCAGCAGCTCG ACCGGAGGGCGATACTTGCAGCCGTTTCAACGAAACGTGATAGTTCCGACTTTTTCTCAGGGCTGGTGTCAACAC ACAGGACTTGTAGACCTAATTCATGTCGAAGTACGGTCTCTTGCTTGTGACGAAAATCTGTTCCGAGAGGCTCAC AGGGCATATCAGGAGGCTCGAAAGAGTCACGGATTCGGAGTCTCAATGATCGTTTCGTCCCGACTTCTTGGCATG GTCCCAAAGGCTCCGCAGAAGCTGCCTAGTCACGTCCAAGTAATATTGGAGAAGACCTTTTCTTGGGCCCATCCG AATCCCTACCGTGACGACTCTAAGACTGTCCGCGTTACTGTGCTGCATTACAACGTTTCGTATATTGCTTCTGTT TAG