© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Ophio5|5024 |
| Gene name | |
| Location | scaffold_401:14429..18143 |
| Strand | + |
| Gene length (bp) | 3714 |
| Transcript length (bp) | 3162 |
| Coding sequence length (bp) | 3159 |
| Protein length (aa) | 1053 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF07651 | ANTH | ANTH domain | 2.1E-79 | 15 | 275 |
| PF01608 | I_LWEQ | I/LWEQ domain | 3.8E-58 | 902 | 1051 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q9P6L5|SLA2_SCHPO | Endocytosis protein end4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=end4 PE=1 SV=2 | 1 | 1051 | 0.0E+00 |
| sp|P33338|SLA2_YEAST | Protein SLA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLA2 PE=1 SV=5 | 10 | 275 | 8.0E-94 |
| sp|O00291|HIP1_HUMAN | Huntingtin-interacting protein 1 OS=Homo sapiens GN=HIP1 PE=1 SV=5 | 18 | 1051 | 8.0E-86 |
| sp|Q9JKY5|HIP1R_MOUSE | Huntingtin-interacting protein 1-related protein OS=Mus musculus GN=Hip1r PE=1 SV=2 | 13 | 1050 | 1.0E-85 |
| sp|P33338|SLA2_YEAST | Protein SLA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLA2 PE=1 SV=5 | 640 | 1050 | 5.0E-70 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q9P6L5|SLA2_SCHPO | Endocytosis protein end4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=end4 PE=1 SV=2 | 1 | 1051 | 0.0E+00 |
| sp|P33338|SLA2_YEAST | Protein SLA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLA2 PE=1 SV=5 | 10 | 275 | 8.0E-94 |
| sp|O00291|HIP1_HUMAN | Huntingtin-interacting protein 1 OS=Homo sapiens GN=HIP1 PE=1 SV=5 | 18 | 1051 | 8.0E-86 |
| sp|Q9JKY5|HIP1R_MOUSE | Huntingtin-interacting protein 1-related protein OS=Mus musculus GN=Hip1r PE=1 SV=2 | 13 | 1050 | 1.0E-85 |
| sp|P33338|SLA2_YEAST | Protein SLA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLA2 PE=1 SV=5 | 640 | 1050 | 5.0E-70 |
| sp|O75146|HIP1R_HUMAN | Huntingtin-interacting protein 1-related protein OS=Homo sapiens GN=HIP1R PE=1 SV=2 | 383 | 1050 | 2.0E-53 |
| sp|Q8VD75|HIP1_MOUSE | Huntingtin-interacting protein 1 OS=Mus musculus GN=Hip1 PE=1 SV=2 | 745 | 1051 | 9.0E-41 |
| sp|Q02328|SLAP2_CAEEL | Huntington interacting protein related 1 OS=Caenorhabditis elegans GN=hipr-1 PE=3 SV=3 | 814 | 1051 | 2.0E-35 |
| sp|Q54K81|TALB_DICDI | Talin-B OS=Dictyostelium discoideum GN=talB PE=2 SV=1 | 856 | 1052 | 2.0E-25 |
| sp|P0CE95|TALA1_DICDI | Talin-A OS=Dictyostelium discoideum GN=talA PE=1 SV=1 | 638 | 1053 | 9.0E-24 |
| sp|Q02328|SLAP2_CAEEL | Huntington interacting protein related 1 OS=Caenorhabditis elegans GN=hipr-1 PE=3 SV=3 | 19 | 440 | 2.0E-23 |
| sp|Q9Y4G6|TLN2_HUMAN | Talin-2 OS=Homo sapiens GN=TLN2 PE=1 SV=4 | 841 | 1051 | 3.0E-21 |
| sp|P26039|TLN1_MOUSE | Talin-1 OS=Mus musculus GN=Tln1 PE=1 SV=2 | 841 | 1051 | 5.0E-20 |
| sp|Q9Y490|TLN1_HUMAN | Talin-1 OS=Homo sapiens GN=TLN1 PE=1 SV=3 | 841 | 1051 | 1.0E-19 |
| sp|P54939|TLN1_CHICK | Talin-1 OS=Gallus gallus GN=TLN1 PE=1 SV=2 | 841 | 1051 | 9.0E-19 |
| sp|Q71LX4|TLN2_MOUSE | Talin-2 OS=Mus musculus GN=Tln2 PE=1 SV=3 | 841 | 982 | 5.0E-16 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0005543 | phospholipid binding | Yes |
| GO:0003779 | actin binding | Yes |
| GO:0008092 | cytoskeletal protein binding | No |
| GO:0005488 | binding | No |
| GO:0005515 | protein binding | No |
| GO:0003674 | molecular_function | No |
| GO:0008289 | lipid binding | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 64 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Ophio5|5024 MAATRTQQHTKTDQELAISIKKATNGEELSPKRKHVRACIVYTWDHRSAQAFWTGIKVQPILADEVQTFKALITI HKVLQEGHPSAIKDAMSNRSWIDGLNRSINGEGIRGYGPLIREYVYYLLAKLSFHQQHPEFNGTFEYEEYLSLKA INDPNEGYETITDLMVLQDKIEQFQKLIFSHFRNVGNNECRISALVPLVQESYGIYKFITSMLRAMYQMTGDEEA LDPLRQRYDAQHYRLVKFYYECSNLRYLTSLITIPKLPQEPPNLLAVDDTAPALPARPRQEIERQPTPPSEPKSE EPGEISEFWKNELDRQNREYEEQQRVLEQRQQAALMAQQQAQMQAQREFDDQQRRLMEQQQREQEALLAQQAQWQ TQGRLAELERENLNARAQYERDQLMLQQYDQRVKALEGELGQIQGSFGQQMASRDEQIRALQEQVNTWRTKYEAL AKLYSQLRHEHLDLLQKFKAVQLKAASAQEAIDRRERLEREIKTKNLELANMIRERDRALHDKDRLSGSNKDEVE RLKRELRMAQERADNVERSKGNELSTMLAKYNREMSDLEEALRNKSRALEEAQARTRDGNSDLEQLLRDKEEELE VYKTGMDQTLMELSELKLSQGDTDTALDGQIDALIMSSLEKITDMMDSVLQSGVSRVDDALYELDSSMQAGNQNA SPSYVLSQIEKASASAMEFATAFNNFIADGPNSEHGEVIKAVSVFSGAVADLCSNTKGLTRLATDDGKTDALMGG ARQSATATVHFFRSLQSFRLTGLEALQKTDVVINSNNEVQMRLQKLSKLVEGFAPGFGKLTHSKGDLGDLVDSEL SKAAAAIEAATARLAKMKNKPREGDGVSTYELRVHDSILDAATAMTSAIAELIRAATVTQQEIVQAGRGSSSRTA FYKKNNRWTEGLISAAKAVASSTNRLIETADGVLSGRNSPEQLIVASNDVAASTAQLVAASRVKAGFMSKSQERL EQASKAVGAACRALVRQVQAMIRERGQDDEQVDYTKLGAHEFKVREMEQQVEILQLENSLASARHRLGEMRKISY QED |
| Coding | >Ophio5|5024 ATGGCGGCAACGCGCACTCAGCAACATACAAAAACCGATCAAGAGCTTGCCATCAGCATCAAAAAGGCTACCAAC GGCGAAGAGCTGTCTCCCAAGCGCAAGCATGTACGCGCCTGTATCGTTTATACATGGGACCACAGGTCTGCTCAG GCCTTCTGGACTGGAATCAAGGTGCAGCCTATTCTCGCCGACGAGGTCCAGACCTTCAAGGCCCTCATCACCATC CACAAGGTGCTCCAAGAGGGCCACCCGTCGGCTATTAAGGATGCCATGTCCAACCGCAGCTGGATTGACGGCCTC AACCGGTCCATCAACGGCGAGGGCATTCGCGGATACGGGCCCTTGATTCGAGAATACGTCTACTACCTACTCGCG AAGCTCTCCTTCCACCAGCAGCACCCCGAGTTCAACGGCACTTTCGAGTACGAGGAATACCTGAGTCTCAAGGCC ATCAACGATCCCAACGAGGGCTATGAAACCATCACCGACCTCATGGTCTTACAGGATAAGATTGAACAGTTTCAG AAGCTCATCTTTTCGCACTTTAGAAACGTCGGTAACAACGAGTGTCGCATCTCCGCTCTCGTGCCGCTGGTGCAG GAGAGTTACGGCATCTACAAGTTCATCACCAGCATGCTGAGGGCCATGTACCAGATGACGGGCGACGAAGAAGCG CTGGACCCCCTACGTCAACGATACGACGCCCAGCACTATCGCCTCGTCAAGTTCTACTACGAATGCTCCAACCTC CGCTACCTCACCAGCCTCATCACCATCCCCAAGCTGCCGCAGGAGCCGCCGAACCTGCTGGCGGTCGACGACACG GCCCCGGCACTGCCAGCCCGGCCCAGGCAGGAGATTGAGCGTCAGCCGACGCCTCCTTCGGAGCCCAAGTCGGAG GAGCCCGGGGAGATTTCGGAATTTTGGAAGAACGAGCTGGACCGGCAGAACCGCGAGTACGAGGAACAGCAGCGG GTGCTGGAGCAGAGGCAACAGGCGGCGCTGATGGCGCAGCAGCAGGCGCAGATGCAGGCGCAGCGCGAGTTCGAC GACCAGCAACGGCGGCTGATGGAGCAGCAGCAGCGGGAACAAGAGGCGTTGCTGGCACAGCAGGCGCAGTGGCAG ACGCAGGGCCGGCTGGCGGAGCTGGAGCGGGAGAACCTCAATGCGCGGGCGCAGTACGAGCGCGACCAGCTGATG CTGCAGCAGTACGACCAGCGGGTCAAGGCTCTCGAGGGCGAGCTGGGCCAGATCCAGGGCAGCTTCGGGCAGCAG ATGGCGAGCCGGGACGAGCAGATCCGGGCGCTCCAGGAGCAGGTCAACACGTGGAGGACAAAGTACGAGGCGCTG GCCAAGCTGTACTCGCAGCTGCGGCACGAGCACCTGGACCTGCTGCAAAAGTTCAAGGCGGTGCAGCTCAAGGCG GCGAGCGCGCAGGAGGCCATCGACCGGCGCGAGCGGCTCGAGCGCGAGATCAAGACGAAGAACCTGGAGCTGGCC AACATGATACGCGAGAGGGACCGGGCGCTTCACGACAAGGACCGGCTCAGCGGGAGCAACAAGGACGAGGTGGAG CGGCTCAAGCGCGAGCTGCGGATGGCGCAGGAGCGGGCGGACAATGTAGAGCGCAGCAAGGGCAACGAGCTGTCG ACGATGCTGGCCAAGTACAACCGAGAAATGAGCGACCTGGAGGAGGCGCTGCGGAACAAGTCGCGAGCGCTCGAG GAGGCGCAGGCGCGGACGCGGGACGGCAACTCGGACCTGGAACAGCTGTTGCGCGACAAGGAGGAGGAGCTCGAG GTGTACAAGACGGGCATGGACCAGACGCTGATGGAGCTGAGCGAGCTCAAGCTGAGCCAGGGCGACACGGACACG GCGCTGGACGGGCAGATTGACGCCCTCATCATGTCGAGCCTGGAGAAGATCACGGACATGATGGACTCGGTGCTG CAGTCGGGCGTCTCGCGCGTCGACGACGCCCTGTACGAGCTGGACTCGTCGATGCAGGCGGGCAACCAGAACGCG TCGCCGTCGTACGTGCTGTCGCAGATTGAGAAGGCGTCGGCGAGCGCCATGGAGTTTGCGACGGCCTTTAACAAC TTCATCGCCGACGGGCCCAACAGCGAGCACGGCGAGGTGATCAAGGCCGTCAGCGTCTTCTCGGGCGCCGTGGCG GACCTCTGCAGCAACACCAAGGGCCTGACGCGACTGGCGACGGACGACGGCAAGACGGACGCCCTCATGGGCGGC GCGCGGCAGTCGGCCACGGCGACGGTCCACTTCTTCCGCAGCCTACAGAGCTTCCGGCTGACGGGCTTGGAGGCG CTGCAGAAGACGGACGTGGTGATCAACAGCAACAACGAGGTGCAGATGCGACTGCAGAAGCTCAGCAAGCTGGTC GAGGGCTTCGCGCCGGGCTTCGGCAAGCTGACGCACAGCAAGGGCGACCTGGGCGACCTGGTCGACTCGGAGCTG AGCAAGGCGGCGGCCGCCATCGAGGCGGCGACGGCGAGGCTGGCCAAGATGAAGAACAAGCCGCGCGAGGGCGAC GGGGTGTCGACGTACGAGCTGCGCGTGCACGACTCCATCCTGGACGCGGCCACGGCCATGACGAGCGCCATCGCC GAGCTGATACGGGCCGCGACGGTGACGCAGCAGGAGATTGTCCAGGCCGGACGCGGATCCTCGTCGCGGACGGCC TTTTACAAGAAGAACAACCGATGGACCGAGGGCCTGATCTCGGCGGCCAAGGCGGTGGCCTCTTCGACCAACAGG CTGATCGAGACGGCCGACGGGGTGCTCTCGGGCCGGAACAGCCCGGAGCAGCTGATTGTGGCGTCCAACGACGTG GCGGCGTCGACGGCTCAGCTGGTGGCGGCCAGCCGCGTCAAGGCCGGCTTCATGTCCAAGAGCCAGGAGAGGTTG GAGCAGGCGAGCAAGGCGGTGGGTGCCGCGTGCCGGGCGCTGGTGCGCCAGGTGCAAGCCATGATACGCGAACGG GGCCAGGACGACGAGCAAGTCGATTACACGAAGCTGGGGGCGCATGAGTTCAAGGTGAGGGAGATGGAGCAGCAG GTCGAGATCTTGCAGCTGGAGAACTCGCTGGCGTCGGCGCGTCACCGACTGGGAGAGATGCGCAAGATTTCCTAC CAAGAAGAC |
| Transcript | >Ophio5|5024 ATGGCGGCAACGCGCACTCAGCAACATACAAAAACCGATCAAGAGCTTGCCATCAGCATCAAAAAGGCTACCAAC GGCGAAGAGCTGTCTCCCAAGCGCAAGCATGTACGCGCCTGTATCGTTTATACATGGGACCACAGGTCTGCTCAG GCCTTCTGGACTGGAATCAAGGTGCAGCCTATTCTCGCCGACGAGGTCCAGACCTTCAAGGCCCTCATCACCATC CACAAGGTGCTCCAAGAGGGCCACCCGTCGGCTATTAAGGATGCCATGTCCAACCGCAGCTGGATTGACGGCCTC AACCGGTCCATCAACGGCGAGGGCATTCGCGGATACGGGCCCTTGATTCGAGAATACGTCTACTACCTACTCGCG AAGCTCTCCTTCCACCAGCAGCACCCCGAGTTCAACGGCACTTTCGAGTACGAGGAATACCTGAGTCTCAAGGCC ATCAACGATCCCAACGAGGGCTATGAAACCATCACCGACCTCATGGTCTTACAGGATAAGATTGAACAGTTTCAG AAGCTCATCTTTTCGCACTTTAGAAACGTCGGTAACAACGAGTGTCGCATCTCCGCTCTCGTGCCGCTGGTGCAG GAGAGTTACGGCATCTACAAGTTCATCACCAGCATGCTGAGGGCCATGTACCAGATGACGGGCGACGAAGAAGCG CTGGACCCCCTACGTCAACGATACGACGCCCAGCACTATCGCCTCGTCAAGTTCTACTACGAATGCTCCAACCTC CGCTACCTCACCAGCCTCATCACCATCCCCAAGCTGCCGCAGGAGCCGCCGAACCTGCTGGCGGTCGACGACACG GCCCCGGCACTGCCAGCCCGGCCCAGGCAGGAGATTGAGCGTCAGCCGACGCCTCCTTCGGAGCCCAAGTCGGAG GAGCCCGGGGAGATTTCGGAATTTTGGAAGAACGAGCTGGACCGGCAGAACCGCGAGTACGAGGAACAGCAGCGG GTGCTGGAGCAGAGGCAACAGGCGGCGCTGATGGCGCAGCAGCAGGCGCAGATGCAGGCGCAGCGCGAGTTCGAC GACCAGCAACGGCGGCTGATGGAGCAGCAGCAGCGGGAACAAGAGGCGTTGCTGGCACAGCAGGCGCAGTGGCAG ACGCAGGGCCGGCTGGCGGAGCTGGAGCGGGAGAACCTCAATGCGCGGGCGCAGTACGAGCGCGACCAGCTGATG CTGCAGCAGTACGACCAGCGGGTCAAGGCTCTCGAGGGCGAGCTGGGCCAGATCCAGGGCAGCTTCGGGCAGCAG ATGGCGAGCCGGGACGAGCAGATCCGGGCGCTCCAGGAGCAGGTCAACACGTGGAGGACAAAGTACGAGGCGCTG GCCAAGCTGTACTCGCAGCTGCGGCACGAGCACCTGGACCTGCTGCAAAAGTTCAAGGCGGTGCAGCTCAAGGCG GCGAGCGCGCAGGAGGCCATCGACCGGCGCGAGCGGCTCGAGCGCGAGATCAAGACGAAGAACCTGGAGCTGGCC AACATGATACGCGAGAGGGACCGGGCGCTTCACGACAAGGACCGGCTCAGCGGGAGCAACAAGGACGAGGTGGAG CGGCTCAAGCGCGAGCTGCGGATGGCGCAGGAGCGGGCGGACAATGTAGAGCGCAGCAAGGGCAACGAGCTGTCG ACGATGCTGGCCAAGTACAACCGAGAAATGAGCGACCTGGAGGAGGCGCTGCGGAACAAGTCGCGAGCGCTCGAG GAGGCGCAGGCGCGGACGCGGGACGGCAACTCGGACCTGGAACAGCTGTTGCGCGACAAGGAGGAGGAGCTCGAG GTGTACAAGACGGGCATGGACCAGACGCTGATGGAGCTGAGCGAGCTCAAGCTGAGCCAGGGCGACACGGACACG GCGCTGGACGGGCAGATTGACGCCCTCATCATGTCGAGCCTGGAGAAGATCACGGACATGATGGACTCGGTGCTG CAGTCGGGCGTCTCGCGCGTCGACGACGCCCTGTACGAGCTGGACTCGTCGATGCAGGCGGGCAACCAGAACGCG TCGCCGTCGTACGTGCTGTCGCAGATTGAGAAGGCGTCGGCGAGCGCCATGGAGTTTGCGACGGCCTTTAACAAC TTCATCGCCGACGGGCCCAACAGCGAGCACGGCGAGGTGATCAAGGCCGTCAGCGTCTTCTCGGGCGCCGTGGCG GACCTCTGCAGCAACACCAAGGGCCTGACGCGACTGGCGACGGACGACGGCAAGACGGACGCCCTCATGGGCGGC GCGCGGCAGTCGGCCACGGCGACGGTCCACTTCTTCCGCAGCCTACAGAGCTTCCGGCTGACGGGCTTGGAGGCG CTGCAGAAGACGGACGTGGTGATCAACAGCAACAACGAGGTGCAGATGCGACTGCAGAAGCTCAGCAAGCTGGTC GAGGGCTTCGCGCCGGGCTTCGGCAAGCTGACGCACAGCAAGGGCGACCTGGGCGACCTGGTCGACTCGGAGCTG AGCAAGGCGGCGGCCGCCATCGAGGCGGCGACGGCGAGGCTGGCCAAGATGAAGAACAAGCCGCGCGAGGGCGAC GGGGTGTCGACGTACGAGCTGCGCGTGCACGACTCCATCCTGGACGCGGCCACGGCCATGACGAGCGCCATCGCC GAGCTGATACGGGCCGCGACGGTGACGCAGCAGGAGATTGTCCAGGCCGGACGCGGATCCTCGTCGCGGACGGCC TTTTACAAGAAGAACAACCGATGGACCGAGGGCCTGATCTCGGCGGCCAAGGCGGTGGCCTCTTCGACCAACAGG CTGATCGAGACGGCCGACGGGGTGCTCTCGGGCCGGAACAGCCCGGAGCAGCTGATTGTGGCGTCCAACGACGTG GCGGCGTCGACGGCTCAGCTGGTGGCGGCCAGCCGCGTCAAGGCCGGCTTCATGTCCAAGAGCCAGGAGAGGTTG GAGCAGGCGAGCAAGGCGGTGGGTGCCGCGTGCCGGGCGCTGGTGCGCCAGGTGCAAGCCATGATACGCGAACGG GGCCAGGACGACGAGCAAGTCGATTACACGAAGCTGGGGGCGCATGAGTTCAAGGTGAGGGAGATGGAGCAGCAG GTCGAGATCTTGCAGCTGGAGAACTCGCTGGCGTCGGCGCGTCACCGACTGGGAGAGATGCGCAAGATTTCCTAC CAAGAAGACTAG |
| Gene | >Ophio5|5024 ATGGCGGCAACGCGCACTCAGCAACATACAAAGTTGGTCTGACGCAGTAATAGCATTATGTGATTTCCGCTGACT CGGCTCACGCGCGCAGAACCGATCAAGAGCTTGCCATCAGCATCAAAAAGGCTACCAACGGCGAAGAGCTGTCTC CCAAGCGCAAGCATGTACGCGCCTGTATCGTTTATACATGGGACCACAGGTCTGCTCAGGCCTTCTGGACTGGAA TCAAGGTGTACGTGCGCGCGTCTTCAACGTCGAGTGATAGCTACAAGGCTCATCAGCCGCGCATAGGCAGCCTAT TCTCGCCGACGAGGTCCAGACCTTCAAGGCCCTCATCACCATCCACAAGGTGCTCCAAGAGGGCCACCCGTCGGC TATTAAGGATGCCATGTCCAACCGCAGCTGGATTGACGGCCTCAACCGGTCCATCAACGGCGAGGGCATTCGCGG ATACGGGCCCTTGATTCGAGAATACGTCTACTACCTACTCGCGAAGCTCTCCTTCCACCAGCAGCACCCCGAGTT CAACGGCACTTTCGAGTACGAGGAATACCTGAGTCTCAAGGCCATCAACGATCCCAACGAGGGCTATGAAACCAT CACCGACCTCATGGTCTTACAGGATAAGATTGAACAGTTTCAGAAGCTCATCTTTTCGCACTTTAGAAACGTCGG TAACAACGAGTGTCGCATCTCCGCTCTCGTGCCGCTGGTGCAGGAGAGTTACGGCATCTACAAGTTCATCACCAG CATGCTGAGGGCCATGTACCAGAGTAAGCGACTCGGCGAGGATCTGTACAGGGCGAGGCGACAAGGCTGACTAGG TGCTGCAGTGACGGGCGACGAAGAAGCGCTGGACCCCCTACGTCAACGATACGACGCCCAGCACTATCGCCTCGT CAAGTTCTACTACGAATGCTCCAACCTCCGCTACCTCACCAGCCTCATCACCATCCCCAAGCTGCCGCAGGAGCC GCCGAACCTGCTGGCGGTCGACGACACGGCCCCGGCACTGCCAGCCCGGCCCAGGCAGGAGATTGAGCGTCAGCC GACGCCTCCTTCGGAGCCCAAGTCGGAGGAGCCCGGGGAGATTTCGGAATTTTGGAAGAACGAGCTGGACCGGCA GAACCGCGAGTACGAGGAACAGCAGCGGGTGCTGGAGCAGAGGCAACAGGCGGCGCTGATGGCGCAGCAGCAGGC GCAGATGCAGGCGCAGCGCGAGTTCGACGACCAGCAACGGCGGCTGATGGAGCAGCAGCAGCGGGAACAAGAGGC GTTGCTGGCACAGCAGGCGCAGTGGCAGACGCAGGGCCGGCTGGCGGAGCTGGAGCGGGAGAACCTCAATGCGCG GGCGCAGTACGAGCGCGACCAGCTGATGCTGCAGCAGTACGACCAGCGGGTCAAGGCTCTCGAGGGCGAGCTGGG CCAGATCCAGGGCAGCTTCGGGCAGCAGATGGCGAGCCGGGACGAGCAGATCCGGGCGCTCCAGGAGCAGGTCAA CACGTGGAGGACAAAGTACGAGGCGCTGGCCAAGCTGTACTCGCAGCTGCGGCACGAGCACCTGGACCTGCTGCA AAAGTTCAAGGCGGTGCAGCTCAAGGCGGCGAGCGCGCAGGAGGCCATCGACCGGCGCGAGCGGCTCGAGCGCGA GATCAAGACGAAGAACCTGGAGCTGGCCAACATGATACGCGAGAGGGACCGGGCGCTTCACGACAAGGACCGGCT CAGCGGGAGCAACAAGGACGAGGTGGAGCGGCTCAAGCGCGAGCTGCGGATGGCGCAGGAGCGGGCGGACAATGT AGAGCGCAGCAAGGGCAACGAGCTGTCGACGATGCTGGCCAAGTACAACCGAGAAATGAGCGACCTGGAGGAGGC GCTGCGGAACAAGTCGCGAGCGCTCGAGGAGGCGCAGGCGCGGACGCGGGACGGCAACTCGGACCTGGAACAGCT GTTGCGCGACAAGGAGGAGGAGCTCGAGGTGTACAAGACGGGCATGGACCAGACGCTGATGGAGCTGAGCGAGCT CAAGCTGAGCCAGGGCGACACGGACACGGCGCTGGACGGGCAGATTGACGCCCTCATCATGTCGAGCCTGGAGAA GATCACGGACATGATGGACTCGGTGCTGCAGTCGGGCGTCTCGCGCGTCGACGACGCCCTGTACGAGCTGGACTC GTCGATGCAGGCGGGCAACCAGAACGCGTCGCCGTCGTACGTGCTGTCGCAGATTGAGAAGGCGTCGGCGAGCGC CATGGAGTTTGCGACGGCCTTTAACAACTTCATCGCCGACGGGCCCAACAGCGAGCACGGCGAGGTGATCAAGGC CGTCAGCGTCTTCTCGGGCGCCGTGGCGGACCTCTGCAGCAACACCAAGGGCCTGACGCGACTGGCGACGGACGA CGGCAAGACGGACGCCCTCATGGGCGGCGCGCGGCAGTCGGCCACGGCGACGGTCCACTTCTTCCGCAGCCTACA GAGCTTCCGGCTGACGGGCTTGGAGGCGCTGCAGAAGACGGACGTGGTGATCAACAGCAACAACGAGGTGCAGAT GCGACTGCAGAAGCTCAGCAAGCTGGTCGAGGGCTTCGCGCCGGGCTTCGGCAAGCTGACGCACAGCAAGGGCGA CCTGGGCGACCTGGTCGACTCGGAGCTGAGCAAGGCGGCGGCCGCCATCGAGGCGGCGACGGCGAGGCTGGCCAA GATGAAGAACAAGCCGCGCGAGGGCGACGGGGTGTCGACGTACGAGCTGCGCGTGCACGACTCCATCCTGGACGC GGCCACGGCCATGACGAGCGCCATCGCCGAGCTGATACGGGCCGCGACGGTGACGCAGCAGGAGATTGTCCAGGC CGGACGCGGATCCTCGTCGCGGACGGCCTTTTACAAGAAGAACAACCGATGGACCGAGGGCCTGATCTCGGCGGC CAAGGCGGTGGCCTCTTCGACCAACAGGCTGATCGAGACGGCCGACGGGGTGCTCTCGGGCCGGAACAGCCCGGA GCAGCTGATTGTGGCGTCCAACGACGTGGCGGCGTCGACGGCTCAGCTGGTGGCGGCCAGCCGCGTCAAGGCCGG CTTCATGTCCAAGAGCCAGGAGAGGTTGGAGCAGGCGAGCAAGGCGGTGGGTGCCGCGTGCCGGGCGCTGGTGCG CCAGGTGCAAGCCATGATACGCGAACGGGGCCAGGACGACGAGCAAGTCGATTACACGAAGCTGGGGGCGCATGA GTTCAAGGTGAGGGAGATGGAGCAGCAGGTGAGTTTTTTTTTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNGTTCCCTTTTCCTCTTTTCTTTTTTTTTGTTTCATCTGGTTTCATTTCTGTCCTTGAGCATTTTCCACCTG TATTGCTCCGCTTACCCCCTCCCTCCCCTTGTTTTACCCCTTTTTACGGTGTTGGTTGTCCTGTTCATGTCAGGG GTCTGTCGAGTGACCGGGGAAGATGATGGGGGCATTTCCAGGCGGGCGAAAAGGGGAAAAGACGACCGTTCTTTG TGTTTTTTTTTTCTTTCCCGATCCGTCACTTGGTTTGCGAGCAGATGACCTTTTTTTTTCCCTTTGACGGTTGTT TTCCTTTGTGCTGACGATGCCCCGCAGGTCGAGATCTTGCAGCTGGAGAACTCGCTGGCGTCGGCGCGTCACCGA CTGGGAGAGATGCGCAAGATTTCCTACCAAGAAGACTAG |